메뉴 건너뛰기




Volumn 27, Issue 3, 2012, Pages 906-912

Long-term mineralocorticoid receptor blockade ameliorates progression of experimental diabetic renal disease

Author keywords

Albuminuria; Aldosterone; Diabetic nephropathy; Fibrosis

Indexed keywords

ALDOSTERONE RECEPTOR; COLLAGEN TYPE 4; CYCLINE; EPLERENONE; GLUCOSE; MINERALOCORTICOID RECEPTOR; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84860531024     PISSN: 09310509     EISSN: 14602385     Source Type: Journal    
DOI: 10.1093/ndt/gfr495     Document Type: Article
Times cited : (27)

References (37)
  • 1
    • 39049189516 scopus 로고    scopus 로고
    • End-stage renal disease in diabetic persons: Is the pandemic subsiding?
    • Friedman AL, Friedman EA, Eggers P. End-stage renal disease in diabetic persons: Is the pandemic subsiding? Kidney Int 2006; 70: 51-54
    • (2006) Kidney Int , vol.70 , pp. 51-54
    • Friedman, A.L.1    Friedman, E.A.2    Eggers, P.3
  • 3
    • 49649085000 scopus 로고    scopus 로고
    • The aggravating mechanisms of aldosterone on kidney fibrosis
    • Remuzzi G, Cattaneo D, Perico N. The aggravating mechanisms of aldosterone on kidney fibrosis. J AmSoc Nephrol 2008; 19: 1459-1462
    • (2008) J AmSoc Nephrol , vol.19 , pp. 1459-1462
    • Remuzzi, G.1    Cattaneo, D.2    Perico, N.3
  • 4
    • 24144495285 scopus 로고    scopus 로고
    • Beneficial effects of adding spironolactone to recommended antihypertensive treatment in diabetic nephropathy: A randomized, double-masked, cross-over study
    • Rossing K, Schjoedt KJ, Smidt UM et al. Beneficial effects of adding spironolactone to recommended antihypertensive treatment in diabetic nephropathy: a randomized, double-masked, cross-over study. Diabetes Care 2005; 28: 2106-2112
    • (2005) Diabetes Care , vol.28 , pp. 2106-2112
    • Rossing, K.1    Schjoedt, K.J.2    Smidt, U.M.3
  • 5
    • 58149125532 scopus 로고    scopus 로고
    • Effects of additive therapy with spironolactone on proteinuria in diabetic patients already on ACE inhibitor or ARB therapy: Results of a randomized, placebo-controlled, double-blind, crossover trial
    • Saklayen MG, Gyebi LK, Tasosa J et al. Effects of additive therapy with spironolactone on proteinuria in diabetic patients already on ACE inhibitor or ARB therapy: results of a randomized, placebo-controlled, double-blind, crossover trial. J Investig Med 2008; 56: 714-719
    • (2008) J Investig Med , vol.56 , pp. 714-719
    • Saklayen, M.G.1    Gyebi, L.K.2    Tasosa, J.3
  • 6
    • 0037222490 scopus 로고    scopus 로고
    • Effectiveness of aldosterone blockade in patients with diabetic nephropathy
    • Sato A, Hayashi K, NaruseMet al. Effectiveness of aldosterone blockade in patients with diabetic nephropathy. Hypertension 2003; 41: 64-68
    • (2003) Hypertension , vol.41 , pp. 64-68
    • Sato, A.1    Hayashi, K.2    Naruse, M.3
  • 7
    • 33746566456 scopus 로고    scopus 로고
    • Beneficial impact of spironolactone on nephrotic range albuminuria in diabetic nephropathy
    • Schjoedt KJ, Rossing K, Juhl TR et al. Beneficial impact of spironolactone on nephrotic range albuminuria in diabetic nephropathy. Kidney Int 2006; 70: 536-542
    • (2006) Kidney Int , vol.70 , pp. 536-542
    • Schjoedt, K.J.1    Rossing, K.2    Juhl, T.R.3
  • 8
    • 33750274950 scopus 로고    scopus 로고
    • Spironolactone in type 2 diabetic nephropathy: Effects on proteinuria, blood pressure and renal function
    • van den Meiracker AH, Baggen RG, Pauli S et al. Spironolactone in type 2 diabetic nephropathy: Effects on proteinuria, blood pressure and renal function. J Hypertens 2006; 24: 2285-2292
    • (2006) J Hypertens , vol.24 , pp. 2285-2292
    • Van Den, M.A.H.1    Baggen, R.G.2    Pauli, S.3
  • 9
    • 4644245230 scopus 로고    scopus 로고
    • Spironolactone prevents early renal injury in streptozotocin-induced diabetic rats
    • Fujisawa G, Okada K, Muto S et al. Spironolactone prevents early renal injury in streptozotocin-induced diabetic rats. Kidney Int 2004; 66: 1493-1502
    • (2004) Kidney Int , vol.66 , pp. 1493-1502
    • Fujisawa, G.1    Okada, K.2    Muto, S.3
  • 10
    • 40649118728 scopus 로고    scopus 로고
    • Spironolactone versus eplerenone for the treatment of idiopathic hyperaldosteronism
    • Karagiannis A, Tziomalos K, Papageorgiou A et al. Spironolactone versus eplerenone for the treatment of idiopathic hyperaldosteronism. Expert Opin Pharmacother 2008; 9: 509-515
    • (2008) Expert Opin Pharmacother , vol.9 , pp. 509-515
    • Karagiannis, A.1    Tziomalos, K.2    Papageorgiou, A.3
  • 11
    • 0026507324 scopus 로고
    • Antihypertensive therapy in a model combining spontaneous hypertension with diabetes
    • Cooper ME, Rumble JR, Allen TJ et al. Antihypertensive therapy in a model combining spontaneous hypertension with diabetes. Kidney Int 1992; 41: 898-903
    • (1992) Kidney Int , vol.41 , pp. 898-903
    • Cooper, M.E.1    Rumble, J.R.2    Allen, T.J.3
  • 12
    • 4043179872 scopus 로고    scopus 로고
    • Additive effects of combined valsartan and spironolactone on cardiac aldosterone escape in spontaneously hypertensive rats
    • Liang YH, Wang JM, Zhou Y et al. Additive effects of combined valsartan and spironolactone on cardiac aldosterone escape in spontaneously hypertensive rats. Life Sci 2004; 75: 1871-1878
    • (2004) Life Sci , vol.75 , pp. 1871-1878
    • Liang, Y.H.1    Wang, J.M.2    Zhou, Y.3
  • 13
    • 33749354007 scopus 로고    scopus 로고
    • Novel effect of mineralocorticoid receptor antagonism to reduce proinflammatory cytokines and hypothalamic activation in rats with ischemia-induced heart failure
    • Kang YM, Zhang ZH, Johnson RF et al. Novel effect of mineralocorticoid receptor antagonism to reduce proinflammatory cytokines and hypothalamic activation in rats with ischemia-induced heart failure. Circ Res 2006; 99: 758-766
    • (2006) Circ Res , vol.99 , pp. 758-766
    • Kang, Y.M.1    Zh, Z.2    Johnson, R.F.3
  • 14
    • 33846453635 scopus 로고    scopus 로고
    • Endogenous relaxin is a naturally occurring modulator of experimental renal tubulointerstitial fibrosis
    • Hewitson TD, Mookerjee I, Masterson R et al. Endogenous relaxin is a naturally occurring modulator of experimental renal tubulointerstitial fibrosis. Endocrinology 2007; 148: 660-669
    • (2007) Endocrinology , vol.148 , pp. 660-669
    • Hewitson, T.D.1    Mookerjee, I.2    Masterson, R.3
  • 15
    • 0036185828 scopus 로고    scopus 로고
    • Effects of low-dose and early versus late perindopril treatment on the progression of severe diabetic nephropathy in (mREN-2)27 rats
    • Mifsud SA, Skinner SL, Cooper ME et al. Effects of low-dose and early versus late perindopril treatment on the progression of severe diabetic nephropathy in (mREN-2)27 rats. J Am Soc Nephrol 2002; 13: 684-692
    • (2002) J Am Soc Nephrol , vol.13 , pp. 684-692
    • Mifsud, S.A.1    Skinner, S.L.2    Cooper, M.E.3
  • 16
    • 0031948169 scopus 로고    scopus 로고
    • Evolution of tubulointerstitial fibrosis in experimental renal infection and scarring
    • Hewitson TD, Darby IA, Bisucci T et al. Evolution of tubulointerstitial fibrosis in experimental renal infection and scarring. J Am Soc Nephrol 1998; 9: 632-642
    • (1998) J Am Soc Nephrol , vol.9 , pp. 632-642
    • Hewitson, T.D.1    Darby, I.A.2    Bisucci, T.3
  • 17
    • 0025215307 scopus 로고
    • Mechanism of activation of latent transforming growth factor beta1 by plasmin
    • Lyons RM, Gentry LE, Purchio AF et al. Mechanism of activation of latent transforming growth factor beta1 by plasmin. J Cell Biol 1990; 110: 1361-1367
    • (1990) J Cell Biol , vol.110 , pp. 1361-1367
    • Lyons, R.M.1    Gentry, L.E.2    Purchio, A.F.3
  • 18
    • 34547828145 scopus 로고    scopus 로고
    • Desmin as a marker of proteinuria in early stages of membranous nephropathy in elderly patients
    • Maruyama M, Sugiyama H, Sada K et al. Desmin as a marker of proteinuria in early stages of membranous nephropathy in elderly patients. Clin Nephrol 2007; 68: 73-80
    • (2007) Clin Nephrol , vol.68 , pp. 73-80
    • Maruyama, M.1    Sugiyama, H.2    Sada, K.3
  • 19
    • 11844291920 scopus 로고    scopus 로고
    • Diabetic nephropathy: Diagnosis, prevention, and treatment
    • Gross JL, de Azevedo MJ, Silveiro SP et al. Diabetic nephropathy: diagnosis, prevention, and treatment. Diabetes Care 2005; 28: 164-176
    • (2005) Diabetes Care , vol.28 , pp. 164-176
    • Gross, J.L.1    De Azevedo, M.J.2    Silveiro, S.P.3
  • 21
    • 0036244244 scopus 로고    scopus 로고
    • Treatment of heart failure in patients with diabetes: Clinical update
    • Bell DS. Treatment of heart failure in patients with diabetes: clinical update. Ethn Dis 2002; 12: S1-S8
    • (2002) Ethn Dis , vol.12
    • Bell, D.S.1
  • 22
    • 0027517659 scopus 로고
    • The effect of angiotensinconverting- enzyme inhibition on diabetic nephropathy
    • Lewis EJ, Hunsicker LG, Bain RP et al. The effect of angiotensinconverting- enzyme inhibition on diabetic nephropathy. N Engl J Med 1993; 329: 977-986
    • (1993) N Engl J Med , vol.329 , pp. 977-986
    • Lewis, E.J.1    Hunsicker, L.G.2    Bain, R.P.3
  • 23
    • 20144369870 scopus 로고    scopus 로고
    • Spironolactone in combination with cilazaprilameliorates proteinuria and renal interstitial fibrosis in rats with anti-Thy-1 irreversible nephritis
    • Asai M, Monkawa T, Marumo T et al. Spironolactone in combination with cilazaprilameliorates proteinuria and renal interstitial fibrosis in rats with anti-Thy-1 irreversible nephritis. Hypertens Res 2004; 27: 971-978
    • (2004) Hypertens Res , vol.27 , pp. 971-978
    • Asai, M.1    Monkawa, T.2    Marumo, T.3
  • 24
    • 33847203614 scopus 로고    scopus 로고
    • Effect of combining ACE inhibition with aldosterone blockade on proteinuria and renal damage in experimental nephrosis
    • Kramer AB, van der Meulen EF, Hamming I et al. Effect of combining ACE inhibition with aldosterone blockade on proteinuria and renal damage in experimental nephrosis. Kidney Int 2007; 71: 417-424
    • (2007) Kidney Int , vol.71 , pp. 417-424
    • Kramer, A.B.1    Van Der Meulen, E.F.2    Hamming, I.3
  • 25
    • 33846443625 scopus 로고    scopus 로고
    • Podocyte as the target for aldosterone: Roles of oxidative stress and Sgk1
    • Shibata S, Nagase M, Yoshida S et al. Podocyte as the target for aldosterone: roles of oxidative stress and Sgk1. Hypertension 2007; 49: 355-364
    • (2007) Hypertension , vol.49 , pp. 355-364
    • Shibata, S.1    Nagase, M.2    Yoshida, S.3
  • 26
    • 0034946204 scopus 로고    scopus 로고
    • Reversal of cardiac and renal fibrosis by pirfenidone and spironolactone in streptozotocin-diabetic rats
    • Miric G, Dallemagne C, Endre Z et al. Reversal of cardiac and renal fibrosis by pirfenidone and spironolactone in streptozotocin-diabetic rats. Br J Pharmacol 2001; 133: 687-694
    • (2001) Br J Pharmacol , vol.133 , pp. 687-694
    • Miric, G.1    Dallemagne, C.2    Endre, Z.3
  • 27
    • 0025008945 scopus 로고
    • MHC class II, antigen presentation and tumor necrosis factor in renal tubular epithelial cells
    • Wuthrich RP, Glimcher LH, Yui MA et al. MHC class II, antigen presentation and tumor necrosis factor in renal tubular epithelial cells. Kidney Int 1990; 37: 783-792
    • (1990) Kidney Int , vol.37 , pp. 783-792
    • Wuthrich, R.P.1    Glimcher, L.H.2    Yui, M.A.3
  • 28
    • 58049209809 scopus 로고    scopus 로고
    • Effect of eplerenone, enalapril and their combination treatment on diabetic nephropathy in type II diabetic rats
    • Kang YS, Ko GJ, Lee MH et al. Effect of eplerenone, enalapril and their combination treatment on diabetic nephropathy in type II diabetic rats. Nephrol Dial Transplant 2009; 24: 73-84
    • (2009) Nephrol Dial Transplant , vol.24 , pp. 73-84
    • Kang, Y.S.1    Ko, G.J.2    Lee, M.H.3
  • 29
    • 77049094652 scopus 로고    scopus 로고
    • Prevention of diabetic kidney disease: Negative clinical trials with renin-angiotensin system inhibitors
    • Nelson RG, Tuttle KR. Prevention of diabetic kidney disease: negative clinical trials with renin-angiotensin system inhibitors. Am J Kidney Dis 2010; 55: 426-430
    • (2010) Am J Kidney Dis , vol.55 , pp. 426-430
    • Nelson, R.G.1    Tuttle, K.R.2
  • 30
    • 33846211917 scopus 로고    scopus 로고
    • Long-term mineralocorticoid receptor blockade reduces fibrosis and improves cardiac performance and coronary hemodynamics in elderly SHR
    • Susic D, Varagic J, Ahn J et al. Long-term mineralocorticoid receptor blockade reduces fibrosis and improves cardiac performance and coronary hemodynamics in elderly SHR. Am J Physiol Heart Circ Physiol 2007; 292: H175-H179
    • (2007) Am J Physiol Heart Circ Physiol , vol.292
    • Susic, D.1    Varagic, J.2    Ahn, J.3
  • 31
    • 0041318968 scopus 로고    scopus 로고
    • Nongenomic vascular action of aldosterone in the glomerular microcirculation
    • Arima S, Kohagura K, Xu HL et al. Nongenomic vascular action of aldosterone in the glomerular microcirculation. J Am Soc Nephrol 2003; 14: 2255-2263
    • (2003) J Am Soc Nephrol , vol.14 , pp. 2255-2263
    • Arima, S.1    Kohagura, K.2    Xu, H.L.3
  • 32
    • 20144365498 scopus 로고    scopus 로고
    • Involvement of aldosterone and mineralocorticoid receptors in rat mesangial cell proliferation and deformability
    • Nishiyama A, Yao L, Fan Y et al. Involvement of aldosterone and mineralocorticoid receptors in rat mesangial cell proliferation and deformability. Hypertension 2005; 45: 710-716
    • (2005) Hypertension , vol.45 , pp. 710-716
    • Nishiyama, A.1    Yao, L.2    Fan, Y.3
  • 33
    • 31544477239 scopus 로고    scopus 로고
    • Aldosterone stimulates collagen gene expression and synthesis via activation of ERK1/2 in rat renal fibroblasts
    • Nagai Y, Miyata K, Sun GP et al. Aldosterone stimulates collagen gene expression and synthesis via activation of ERK1/2 in rat renal fibroblasts. Hypertension 2005; 46: 1039-1045
    • (2005) Hypertension , vol.46 , pp. 1039-1045
    • Nagai, Y.1    Miyata, K.2    Sun, G.P.3
  • 34
    • 33751236177 scopus 로고    scopus 로고
    • Mineralocorticoid receptor antagonist reduces renal injury in rodent models of types 1 and 2 diabetes mellitus
    • Guo C, Martinez-Vasquez D, Mendez GP et al. Mineralocorticoid receptor antagonist reduces renal injury in rodent models of types 1 and 2 diabetes mellitus. Endocrinology 2006; 147: 5363-5373
    • (2006) Endocrinology , vol.147 , pp. 5363-5373
    • Guo, C.1    Martinez-Vasquez, D.2    Mendez, G.P.3
  • 35
    • 12144286297 scopus 로고    scopus 로고
    • Possible contributions of reactive oxygen species and mitogen-activated protein kinase to renal injury in aldosterone/salt-induced hypertensive rats
    • Nishiyama A, Yao L, Nagai Y et al. Possible contributions of reactive oxygen species and mitogen-activated protein kinase to renal injury in aldosterone/salt-induced hypertensive rats. Hypertension 2004; 43: 841-848
    • (2004) Hypertension , vol.43 , pp. 841-848
    • Nishiyama, A.1    Yao, L.2    Nagai, Y.3
  • 36
    • 77149130935 scopus 로고    scopus 로고
    • Involvement of mineralocorticoid receptor in high glucose-induced big mitogen-activated protein kinase 1 activation and mesangial cell proliferation
    • Liu G, Miyata K, Hitomi H et al. Involvement of mineralocorticoid receptor in high glucose-induced big mitogen-activated protein kinase 1 activation and mesangial cell proliferation. J Hypertens 2010; 28: 536-542
    • (2010) J Hypertens , vol.28 , pp. 536-542
    • Liu, G.1    Miyata, K.2    Hitomi, H.3
  • 37
    • 36349013809 scopus 로고    scopus 로고
    • Beneficial effects of spironolactone on glomerular injury in streptozotocin-induced diabetic rats
    • Yuan J, Jia R, Bao Y. Beneficial effects of spironolactone on glomerular injury in streptozotocin-induced diabetic rats. J Renin Angiotensin Aldosterone Syst 2007; 8: 118-126
    • (2007) J Renin Angiotensin Aldosterone Syst , vol.8 , pp. 118-126
    • Yuan, J.1    Jia, R.2    Bao, Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.