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Volumn 11, Issue 4, 2016, Pages

Safety of eplerenone for kidney-transplant recipients with impaired renal function and receiving cyclosporine A

Author keywords

[No Author keywords available]

Indexed keywords

BICARBONATE; CYCLOSPORIN A; EPLERENONE; POTASSIUM; RESIN; CYCLOSPORIN; IMMUNOSUPPRESSIVE AGENT; MINERALOCORTICOID ANTAGONIST; SPIRONOLACTONE;

EID: 84978903960     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0153635     Document Type: Article
Times cited : (21)

References (51)
  • 1
    • 84885960929 scopus 로고    scopus 로고
    • Maintenance immunosuppression in renal transplantation
    • Epub 2013/06/05. PMID: 23731524
    • Menon MC, Murphy B. Maintenance immunosuppression in renal transplantation. Current opinion in pharmacology. 2013; 13(4):662-71. Epub 2013/06/05. doi: 10.1016/j.coph.2013.05.004 PMID: 23731524.
    • (2013) Current opinion in pharmacology , vol.13 , Issue.4 , pp. 662-671
    • Menon, M.C.1    Murphy, B.2
  • 2
    • 0344666767 scopus 로고    scopus 로고
    • The natural history of chronic allograft nephropathy
    • Epub 2003/12/12. PMID: 14668458
    • Nankivell BJ, Borrows RJ, Fung CL, O'Connell PJ, Allen RD, Chapman JR. The natural history of chronic allograft nephropathy. N Engl J Med. 2003; 349(24):2326-33. Epub 2003/12/12. doi: 10.1056/ NEJMoa020009349/24/2326 [pii]. PMID: 14668458.
    • (2003) N Engl J Med , vol.349 , Issue.24 , pp. 2326-2333
    • Nankivell, B.J.1    Borrows, R.J.2    Fung, C.L.3    O'Connell, P.J.4    Allen, R.D.5    Chapman, J.R.6
  • 3
    • 65549166679 scopus 로고    scopus 로고
    • Calcineurin inhibitor nephrotoxicity
    • 4/2/481 Epub 2009/02/17. PMID: 19218475
    • Naesens M, Kuypers DR, Sarwal M. Calcineurin inhibitor nephrotoxicity. Clin J Am Soc Nephrol. 2009; 4(2):481-508. Epub 2009/02/17. doi: 4/2/481 [pii] doi: 10.2215/CJN.04800908 PMID: 19218475.
    • (2009) Clin J Am Soc Nephrol , vol.4 , Issue.2 , pp. 481-508
    • Naesens, M.1    Kuypers, D.R.2    Sarwal, M.3
  • 4
    • 0023370667 scopus 로고
    • Cyclosporine-induced acute renal dysfunction in the rat. Evidence of arteriolar vasoconstriction with preservation of tubular function
    • Epub 1987/07/01. PMID: 3603674
    • English J, Evan A, Houghton DC, Bennett WM. Cyclosporine-induced acute renal dysfunction in the rat. Evidence of arteriolar vasoconstriction with preservation of tubular function. Transplantation. 1987; 44(1):135-41. Epub 1987/07/01. PMID: 3603674.
    • (1987) Transplantation , vol.44 , Issue.1 , pp. 135-141
    • English, J.1    Evan, A.2    Houghton, D.C.3    Bennett, W.M.4
  • 5
    • 78650399880 scopus 로고    scopus 로고
    • Eplerenone in patients with systolic heart failure and mild symptoms
    • Epub 2010/11/16 PMID: 21073363
    • Zannad F, McMurray JJ, Krum H, van Veldhuisen DJ, Swedberg K, Shi H, et al. Eplerenone in patients with systolic heart failure and mild symptoms. N Engl J Med. 2011; 364(1):11-21. Epub 2010/11/16. doi: 10.1056/NEJMoa1009492 PMID: 21073363.
    • (2011) N Engl J Med , vol.364 , Issue.1 , pp. 11-21
    • Zannad, F.1    McMurray, J.J.2    Krum, H.3    Van Veldhuisen, D.J.4    Swedberg, K.5    Shi, H.6
  • 6
    • 0037417252 scopus 로고    scopus 로고
    • Eplerenone, a selective aldosterone blocker, in patients with left ventricular dysfunction after myocardial infarction
    • Epub 2003/04/02. NEJMoa030207 [pii]. PMID: 12668699
    • Pitt B, Remme W, Zannad F, Neaton J, Martinez F, Roniker B, et al. Eplerenone, a selective aldosterone blocker, in patients with left ventricular dysfunction after myocardial infarction. N Engl J Med. 2003; 348(14):1309-21. Epub 2003/04/02. doi: 10.1056/NEJMoa030207 NEJMoa030207 [pii]. PMID: 12668699.
    • (2003) N Engl J Med , vol.348 , Issue.14 , pp. 1309-1321
    • Pitt, B.1    Remme, W.2    Zannad, F.3    Neaton, J.4    Martinez, F.5    Roniker, B.6
  • 7
    • 77954434421 scopus 로고    scopus 로고
    • The endothelial mineralocorticoid receptor regulates vasoconstrictor tone and blood pressure
    • Epub 2010/03/20. doi: fj.09-147926 [pii] PMID: 20299606
    • Nguyen Dinh Cat A, Griol-Charhbili V, Loufrani L, Labat C, Benjamin L, Farman N, et al. The endothelial mineralocorticoid receptor regulates vasoconstrictor tone and blood pressure. FASEB J. 2010; 24 (7):2454-63. Epub 2010/03/20. doi: fj.09-147926 [pii] doi: 10.1096/fj.09-147926 PMID: 20299606.
    • (2010) FASEB J , vol.24 , Issue.7 , pp. 2454-2463
    • Nguyen Dinh Cat, A.1    Griol-Charhbili, V.2    Loufrani, L.3    Labat, C.4    Benjamin, L.5    Farman, N.6
  • 8
    • 84868662652 scopus 로고    scopus 로고
    • Direct regulation of blood pressure by smooth muscle cell mineralocorticoid receptors
    • Epub 2012/08/28. PMID: 22922412; PubMed Central PMCID: PMC3491085
    • McCurley A, Pires PW, Bender SB, Aronovitz M, Zhao MJ, Metzger D, et al. Direct regulation of blood pressure by smooth muscle cell mineralocorticoid receptors. Nature medicine. 2012; 18(9):1429-33. Epub 2012/08/28. doi: 10.1038/nm.2891 PMID: 22922412; PubMed Central PMCID: PMC3491085.
    • (2012) Nature medicine , vol.18 , Issue.9 , pp. 1429-1433
    • McCurley, A.1    Pires, P.W.2    Bender, S.B.3    Aronovitz, M.4    Zhao, M.J.5    Metzger, D.6
  • 9
    • 6444245944 scopus 로고    scopus 로고
    • Therapeutic benefit of spironolactone in experimental chronic cyclosporine A nephrotoxicity
    • Epub 2002/ 12/11. doi: kid707 [pii] PMID: 12472767
    • Feria I, Pichardo I, Juarez P, Ramirez V, Gonzalez MA, Uribe N, et al. Therapeutic benefit of spironolactone in experimental chronic cyclosporine A nephrotoxicity. Kidney Int. 2003; 63(1):43-52. Epub 2002/ 12/11. doi: kid707 [pii] doi: 10.1046/j.1523-1755.2003.00707.x PMID: 12472767.
    • (2003) Kidney Int , vol.63 , Issue.1 , pp. 43-52
    • Feria, I.1    Pichardo, I.2    Juarez, P.3    Ramirez, V.4    Gonzalez, M.A.5    Uribe, N.6
  • 10
    • 26844546641 scopus 로고    scopus 로고
    • Renocortical mRNA expression of vasoactive factors during spironolactone protective effect in chronic cyclosporine nephrotoxicity
    • Epub 2005/07/07. doi: 00166.2005 [pii] PMID: 15998842
    • Perez-Rojas JM, Derive S, Blanco JA, Cruz C, Martinez de la Maza L, Gamba G, et al. Renocortical mRNA expression of vasoactive factors during spironolactone protective effect in chronic cyclosporine nephrotoxicity. Am J Physiol Renal Physiol. 2005; 289(5):F1020-30. Epub 2005/07/07. doi: 00166.2005 [pii] doi: 10.1152/ajprenal.00166.2005 PMID: 15998842.
    • (2005) Am J Physiol Renal Physiol , vol.289 , Issue.5 , pp. F1020-F1030
    • Perez-Rojas, J.M.1    Derive, S.2    Blanco, J.A.3    Cruz, C.4    De La Martinez Maza, L.5    Gamba, G.6
  • 11
    • 58549092050 scopus 로고    scopus 로고
    • Inhibition of mineralocorticoid receptors with eplerenone alleviates short-term cyclosporin A nephrotoxicity in conscious rats
    • gfn204 Epub 2008/04/22. PMID: 18424460
    • Nielsen FT, Jensen BL, Marcussen N, Skott O, Bie P. Inhibition of mineralocorticoid receptors with eplerenone alleviates short-term cyclosporin A nephrotoxicity in conscious rats. Nephrol Dial Transplant. 2008; 23(9):2777-83. Epub 2008/04/22. doi: gfn204 [pii] doi: 10.1093/ndt/gfn204 PMID: 18424460.
    • (2008) Nephrol Dial Transplant , vol.23 , Issue.9 , pp. 2777-2783
    • Nielsen, F.T.1    Jensen, B.L.2    Marcussen, N.3    Skott, O.4    Bie, P.5
  • 12
    • 84930915402 scopus 로고    scopus 로고
    • Inhibition of local aldosterone by eplerenone reduces renal structural damage in a novel model of chronic cyclosporine A nephrotoxicity
    • Epub 2014/12/17. PMID: 25500744
    • Sun QL, Li M, Rui HL, Chen YP. Inhibition of local aldosterone by eplerenone reduces renal structural damage in a novel model of chronic cyclosporine A nephrotoxicity. Journal of the renin-angiotensinaldosterone system: JRAAS. 2015; 16(2):301-10. Epub 2014/12/17. doi: 10.1177/1470320314561248 PMID: 25500744.
    • (2015) Journal of the Renin-Angiotensinaldosterone System: JRAAS , vol.16 , Issue.2 , pp. 301-310
    • Sun, Q.L.1    Li, M.2    Rui, H.L.3    Chen, Y.P.4
  • 13
    • 84942683836 scopus 로고    scopus 로고
    • Deletion of mineralocorticoid receptors in smooth muscle cells blunts renal vascular resistance following acute cyclosporine administration
    • Epub 2015/10/01. PMID: 26422501
    • Amador CA, Bertocchio JP, Andre-Gregoire G, Placier S, Duong Van Huyen JP, El Moghrabi S, et al. Deletion of mineralocorticoid receptors in smooth muscle cells blunts renal vascular resistance following acute cyclosporine administration. Kidney Int. 2015. Epub 2015/10/01. doi: 10.1038/ki.2015.312 PMID: 26422501.
    • (2015) Kidney Int
    • Amador, C.A.1    Bertocchio, J.P.2    Andre-Gregoire, G.3    Placier, S.4    Van Duong Huyen, J.P.5    El Moghrabi, S.6
  • 14
    • 84896109810 scopus 로고    scopus 로고
    • Incidence, determinants, and prognostic significance of hyperkalemia and worsening renal function in patients with heart failure receiving the mineralocorticoid receptor antagonist eplerenone or placebo in addition to optimal medical therapy: Results from the eplerenone in mild patients hospitalization and survival study in heart failure (EMPHASIS-HF)
    • Epub 2013/12/04. PMID: 24297687
    • Rossignol P, Dobre D, McMurray JJ, Swedberg K, Krum H, van Veldhuisen DJ, et al. Incidence, determinants, and prognostic significance of hyperkalemia and worsening renal function in patients with heart failure receiving the mineralocorticoid receptor antagonist eplerenone or placebo in addition to optimal medical therapy: results from the Eplerenone in Mild Patients Hospitalization and Survival Study in Heart Failure (EMPHASIS-HF). Circulation Heart failure. 2014; 7(1):51-8. Epub 2013/12/04. doi: 10.1161/CIRCHEARTFAILURE.113.000792 PMID: 24297687.
    • (2014) Circulation Heart failure , vol.7 , Issue.1 , pp. 51-58
    • Rossignol, P.1    Dobre, D.2    McMurray, J.J.3    Swedberg, K.4    Krum, H.5    Van Veldhuisen, D.J.6
  • 15
    • 84856997580 scopus 로고    scopus 로고
    • The safety and tolerability of spironolactone in patients with mild to moderate chronic kidney disease
    • Epub 2011/09/29. PMID: 21950312; PubMed Central PMCID: PMC3370349
    • Edwards NC, Steeds RP, Chue CD, Stewart PM, Ferro CJ, Townend JN. The safety and tolerability of spironolactone in patients with mild to moderate chronic kidney disease. British journal of clinical pharmacology. 2012; 73(3):447-54. Epub 2011/09/29. doi: 10.1111/j.1365-2125.2011.04102.x PMID: 21950312; PubMed Central PMCID: PMC3370349.
    • (2012) British Journal of Clinical Pharmacology , vol.73 , Issue.3 , pp. 447-454
    • Edwards, N.C.1    Steeds, R.P.2    Chue, C.D.3    Stewart, P.M.4    Ferro, C.J.5    Townend, J.N.6
  • 16
    • 77958533631 scopus 로고    scopus 로고
    • Addition of spironolactone to dual blockade of renin angiotensin system dramatically reduces severe proteinuria in renal transplant patients: An uncontrolled pilot study at 6 months
    • Epub 2010/10/26. S0041-1345(10)01224-8 [pii] PMID: 20970564
    • Gonzalez Monte E, Andres A, Polanco N, Toribio MJ, Santana R, Gutierrez Martinez E, et al. Addition of spironolactone to dual blockade of renin angiotensin system dramatically reduces severe proteinuria in renal transplant patients: an uncontrolled pilot study at 6 months. Transplant Proc. 2010; 42 (8):2899-901. Epub 2010/10/26. doi: S0041-1345(10)01224-8 [pii] doi: 10.1016/j.transproceed.2010. 08.024 PMID: 20970564.
    • (2010) Transplant Proc. , vol.42 , Issue.8 , pp. 2899-2901
    • Gonzalez Monte, E.1    Andres, A.2    Polanco, N.3    Toribio, M.J.4    Santana, R.5    Gutierrez Martinez, E.6
  • 17
    • 0024536437 scopus 로고
    • Optimal two-stage designs for phase II clinical trials
    • PMID: 2702835
    • Simon R. Optimal two-stage designs for phase II clinical trials. Control Clin Trials. 1989; 10(1):1-10. PMID: 2702835.
    • (1989) Control Clin Trials , vol.10 , Issue.1 , pp. 1-10
    • Simon, R.1
  • 19
    • 0033517302 scopus 로고    scopus 로고
    • The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study Investigators
    • Epub 1999/09/02. PMID: 10471456
    • Pitt B, Zannad F, Remme WJ, Cody R, Castaigne A, Perez A, et al. The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study Investigators. N Engl J Med. 1999; 341(10):709-17. Epub 1999/09/02. PMID: 10471456.
    • (1999) N Engl J Med , vol.341 , Issue.10 , pp. 709-717
    • Pitt, B.1    Zannad, F.2    Remme, W.J.3    Cody, R.4    Castaigne, A.5    Perez, A.6
  • 20
    • 3442886513 scopus 로고    scopus 로고
    • Rates of hyperkalemia after publication of the Randomized Aldactone Evaluation Study
    • Epub 2004/08/06. PMID: 15295047
    • Juurlink DN, Mamdani MM, Lee DS, Kopp A, Austin PC, Laupacis A, et al. Rates of hyperkalemia after publication of the Randomized Aldactone Evaluation Study. N Engl J Med. 2004; 351(6):543-51. Epub 2004/08/06. doi: 10.1056/NEJMoa040135351/6/543 [pii]. PMID: 15295047.
    • (2004) N Engl J Med , vol.351 , Issue.6 , pp. 543-551
    • Juurlink, D.N.1    Mamdani, M.M.2    Lee, D.S.3    Kopp, A.4    Austin, P.C.5    Laupacis, A.6
  • 21
    • 84869840351 scopus 로고    scopus 로고
    • Associations between aldosterone antagonist therapy and risks of mortality and readmission among patients with heart failure and reduced ejection fraction
    • Epub 2012/11/29. PMID: 23188026
    • Hernandez AF, Mi X, Hammill BG, Hammill SC, Heidenreich PA, Masoudi FA, et al. Associations between aldosterone antagonist therapy and risks of mortality and readmission among patients with heart failure and reduced ejection fraction. Jama. 2012; 308(20):2097-107. Epub 2012/11/29. doi: 10. 1001/jama.2012.14795 PMID: 23188026.
    • (2012) Jama , vol.308 , Issue.20 , pp. 2097-2107
    • Hernandez, A.F.1    Mi, X.2    Hammill, B.G.3    Hammill, S.C.4    Heidenreich, P.A.5    Masoudi, F.A.6
  • 22
    • 84907389177 scopus 로고    scopus 로고
    • Incidence, predictors, and outcomes related to hypo- and hyperkalemia in patients with severe heart failure treated with a mineralocorticoid receptor antagonist
    • Epub 2014/05/09. PMID: 24812304
    • Vardeny O, Claggett B, Anand I, Rossignol P, Desai AS, Zannad F, et al. Incidence, predictors, and outcomes related to hypo- and hyperkalemia in patients with severe heart failure treated with a mineralocorticoid receptor antagonist. Circulation Heart failure. 2014; 7(4):573-9. Epub 2014/05/09. doi: 10. 1161/CIRCHEARTFAILURE.114.001104 PMID: 24812304.
    • (2014) Circulation Heart failure , vol.7 , Issue.4 , pp. 573-579
    • Vardeny, O.1    Claggett, B.2    Anand, I.3    Rossignol, P.4    Desai, A.S.5    Zannad, F.6
  • 23
    • 0029964782 scopus 로고    scopus 로고
    • Frequency of hyperkalemia in recipients of simultaneous pancreas and kidney transplants with bladder drainage
    • Epub 1996/10/27. PMID: 8900321
    • Kaplan B, Wang Z, Abecassis MM, Fryer JP, Stuart FP, Kaufman DB. Frequency of hyperkalemia in recipients of simultaneous pancreas and kidney transplants with bladder drainage. Transplantation. 1996; 62(8):1174-5. Epub 1996/10/27. PMID: 8900321.
    • (1996) Transplantation , vol.62 , Issue.8 , pp. 1174-1175
    • Kaplan, B.1    Wang, Z.2    Abecassis, M.M.3    Fryer, J.P.4    Stuart, F.P.5    Kaufman, D.B.6
  • 24
    • 44449102631 scopus 로고    scopus 로고
    • ACE-inhibitor or AT2-antagonist therapy of renal transplant recipients is associated with an increase in serum potassium concentrations
    • Epub 2008/02/01. PMID: 18234845
    • Mitterbauer C, Heinze G, Kainz A, Kramar R, Horl WH, Oberbauer R. ACE-inhibitor or AT2-antagonist therapy of renal transplant recipients is associated with an increase in serum potassium concentrations. Nephrol Dial Transplant. 2008; 23(5):1742-6. Epub 2008/02/01. doi: 10.1093/ndt/gfm864 PMID: 18234845.
    • (2008) Nephrol Dial Transplant , vol.23 , Issue.5 , pp. 1742-1746
    • Mitterbauer, C.1    Heinze, G.2    Kainz, A.3    Kramar, R.4    Horl, W.H.5    Oberbauer, R.6
  • 25
    • 2442703936 scopus 로고    scopus 로고
    • Cyclosporine A attenuates the natriuretic action of loop diuretics by inhibition of renal COX-2 expression
    • Epub 2004/05/20. PMID: 15149320
    • Hocherl K, Kees F, Kramer BK, Kurtz A. Cyclosporine A attenuates the natriuretic action of loop diuretics by inhibition of renal COX-2 expression. Kidney Int. 2004; 65(6):2071-80. Epub 2004/05/20. doi: 10. 1111/j.1523-1755.2004.00627.x PMID: 15149320 .
    • (2004) Kidney Int , vol.65 , Issue.6 , pp. 2071-2080
    • Hocherl, K.1    Kees, F.2    Kramer, B.K.3    Kurtz, A.4
  • 26
    • 80052633099 scopus 로고    scopus 로고
    • Cyclosporine metabolic side effects: Association with the WNK4 system
    • Epub 2011/03/26. PMID: 21434893
    • Melnikov S, Mayan H, Uchida S, Holtzman EJ, Farfel Z. Cyclosporine metabolic side effects: association with the WNK4 system. European journal of clinical investigation. 2011; 41(10):1113-20. Epub 2011/03/26. doi: 10.1111/j.1365-2362.2011.02517.x PMID: 21434893.
    • (2011) European journal of clinical investigation , vol.41 , Issue.10 , pp. 1113-1120
    • Melnikov, S.1    Mayan, H.2    Uchida, S.3    Holtzman, E.J.4    Farfel, Z.5
  • 27
    • 80053966270 scopus 로고    scopus 로고
    • The calcineurin inhibitor tacrolimus activates the renal sodium chloride cotransporter to cause hypertension
    • Epub 2011/10/04. PMID: 21963515; PubMed Central PMCID: PMC3192268
    • Hoorn EJ, Walsh SB, McCormick JA, Furstenberg A, Yang CL, Roeschel T, et al. The calcineurin inhibitor tacrolimus activates the renal sodium chloride cotransporter to cause hypertension. Nature medicine. 2011; 17(10):1304-9. Epub 2011/10/04. doi: 10.1038/nm.2497 PMID: 21963515; PubMed Central PMCID: PMC3192268.
    • (2011) Nature medicine , vol.17 , Issue.10 , pp. 1304-1309
    • Hoorn, E.J.1    Walsh, S.B.2    McCormick, J.A.3    Furstenberg, A.4    Yang, C.L.5    Roeschel, T.6
  • 28
    • 41549128429 scopus 로고    scopus 로고
    • K restriction inhibits protein phosphatase 2B (PP2B) and suppression of PP2B decreases ROMK channel activity in the CCD
    • Epub 2008/01/11. PMID: 18184875; PubMed Central PMCID: PMC2734475
    • Zhang Y, Lin DH, Wang ZJ, Jin Y, Yang B, Wang WH. K restriction inhibits protein phosphatase 2B (PP2B) and suppression of PP2B decreases ROMK channel activity in the CCD. American journal of physiology Cell physiology. 2008; 294(3):C765-73. Epub 2008/01/11. doi: 10.1152/ajpcell.00528.2007 PMID: 18184875; PubMed Central PMCID: PMC2734475.
    • (2008) American Journal of Physiology Cell Physiology , vol.294 , Issue.3 , pp. C765-C773
    • Zhang, Y.1    Lin, D.H.2    Wang, Z.J.3    Jin, Y.4    Yang, B.5    Wang, W.H.6
  • 29
    • 33847663254 scopus 로고    scopus 로고
    • Renal tubular acidosis after kidney transplantation-incidence, risk factors and clinical implications
    • Epub 2007/01/11. PMID: 17210594
    • Keven K, Ozturk R, Sengul S, Kutlay S, Ergun I, Erturk S, et al. Renal tubular acidosis after kidney transplantation-incidence, risk factors and clinical implications. Nephrol Dial Transplant. 2007; 22 (3):906-10. Epub 2007/01/11. doi: 10.1093/ndt/gfl714 PMID: 17210594.
    • (2007) Nephrol Dial Transplant , vol.22 , Issue.3 , pp. 906-910
    • Keven, K.1    Ozturk, R.2    Sengul, S.3    Kutlay, S.4    Ergun, I.5    Erturk, S.6
  • 30
    • 0022574662 scopus 로고
    • Hyperchloremic metabolic acidosis with high serum potassium in renal transplant recipients: A cyclosporine A associated side effect
    • Epub 1986/05/01. PMID: 3521998
    • Stahl RA, Kanz L, Maier B, Schollmeyer P. Hyperchloremic metabolic acidosis with high serum potassium in renal transplant recipients: a cyclosporine A associated side effect. Clinical nephrology. 1986; 25(5):245-8. Epub 1986/05/01. PMID: 3521998.
    • (1986) Clinical nephrology , vol.25 , Issue.5 , pp. 245-248
    • Stahl, R.A.1    Kanz, L.2    Maier, B.3    Schollmeyer, P.4
  • 31
    • 0025741287 scopus 로고
    • Influence of ciclosporin A on renal tubular function after kidney transplantation
    • Epub 1991/01/01. PMID: 1658670
    • Heering P, Grabensee B. Influence of ciclosporin A on renal tubular function after kidney transplantation. Nephron. 1991; 59(1):66-70. Epub 1991/01/01. PMID: 1658670.
    • (1991) Nephron , vol.59 , Issue.1 , pp. 66-70
    • Heering, P.1    Grabensee, B.2
  • 32
    • 0027222930 scopus 로고
    • Nephron segment-specific inhibition of Na+/K(+)-ATPase activity by cyclosporin A
    • Epub 1993/01/01. PMID: 8381891
    • Tumlin JA, Sands JM. Nephron segment-specific inhibition of Na+/K(+)-ATPase activity by cyclosporin A. Kidney Int. 1993; 43(1):246-51. Epub 1993/01/01. PMID: 8381891.
    • (1993) Kidney Int. , vol.43 , Issue.1 , pp. 246-251
    • Tumlin, J.A.1    Sands, J.M.2
  • 33
    • 0033728851 scopus 로고    scopus 로고
    • Acid-base and endocrine effects of aldosterone and angiotensin II inhibition in metabolic acidosis in human patients
    • Epub 2000/11/18. PMID: 11079465
    • Henger A, Tutt P, Riesen WF, Hulter HN, Krapf R. Acid-base and endocrine effects of aldosterone and angiotensin II inhibition in metabolic acidosis in human patients. J Lab Clin Med. 2000; 136(5):379-89. Epub 2000/11/18. doi: 10.1067/mlc.2000.110371 PMID: 11079465.
    • (2000) J Lab Clin Med , vol.136 , Issue.5 , pp. 379-389
    • Henger, A.1    Tutt, P.2    Riesen, W.F.3    Hulter, H.N.4    Krapf, R.5
  • 34
    • 84924047041 scopus 로고    scopus 로고
    • Current status of bicarbonate in CKD
    • Epub 2014/08/26. PMID: 25150154; PubMed Central PMCID: PMC4341479
    • Dobre M, Rahman M, Hostetter TH. Current status of bicarbonate in CKD. J Am Soc Nephrol. 2015; 26 (3):515-23. Epub 2014/08/26. doi: 10.1681/ASN.2014020205 PMID: 25150154; PubMed Central PMCID: PMC4341479.
    • (2015) J Am Soc Nephrol , vol.26 , Issue.3 , pp. 515-523
    • Dobre, M.1    Rahman, M.2    Hostetter, T.H.3
  • 35
    • 58149485463 scopus 로고    scopus 로고
    • Timing of onset of CKDrelated metabolic complications
    • Epub 2008/11/14. PMID: 19005010; PubMed Central PMCID: PMC2615728
    • Moranne O, Froissart M, Rossert J, Gauci C, Boffa JJ, Haymann JP, et al. Timing of onset of CKDrelated metabolic complications. J Am Soc Nephrol. 2009; 20(1):164-71. Epub 2008/11/14. doi: 10. 1681/ASN.2008020159 PMID: 19005010; PubMed Central PMCID: PMC2615728.
    • (2009) J Am Soc Nephrol , vol.20 , Issue.1 , pp. 164-171
    • Moranne, O.1    Froissart, M.2    Rossert, J.3    Gauci, C.4    Boffa, J.J.5    Haymann, J.P.6
  • 36
    • 65649142017 scopus 로고    scopus 로고
    • A new equation to estimate glomerular filtration rate
    • Epub 2009/05/06. PMID: 19414839; PubMed Central PMCID: PMC2763564
    • Levey AS, Stevens LA, Schmid CH, Zhang YL, Castro AF 3rd, Feldman HI, et al. A new equation to estimate glomerular filtration rate. Ann Intern Med. 2009; 150(9):604-12. Epub 2009/05/06. PMID: 19414839; PubMed Central PMCID: PMC2763564.
    • (2009) Ann Intern Med , vol.150 , Issue.9 , pp. 604-612
    • Levey, A.S.1    Stevens, L.A.2    Schmid, C.H.3    Zhang, Y.L.4    Castro, A.F.5    Feldman, H.I.6
  • 37
    • 84893720936 scopus 로고    scopus 로고
    • Converging indications of aldosterone antagonists (spironolactone and eplerenone): A narrative review of safety profiles
    • Epub 2014/01/11. PMID: 24407447
    • Danjuma MI, Mukherjee I, Makaronidis J, Osula S. Converging indications of aldosterone antagonists (spironolactone and eplerenone): a narrative review of safety profiles. Current hypertension reports. 2014; 16(2):414. Epub 2014/01/11. doi: 10.1007/s11906-013-0414-8 PMID: 24407447.
    • (2014) Current Hypertension Reports , vol.16 , Issue.2 , pp. 414
    • Danjuma, M.I.1    Mukherjee, I.2    Makaronidis, J.3    Osula, S.4
  • 38
    • 84896122288 scopus 로고    scopus 로고
    • Guideline concordance of testing for hyperkalemia and kidney dysfunction during initiation of mineralocorticoid receptor antagonist therapy in patients with heart failure
    • Epub 2013/11
    • Allen LA, Shetterly SM, Peterson PN, Gurwitz JH, Smith DH, Brand DW, et al. Guideline concordance of testing for hyperkalemia and kidney dysfunction during initiation of mineralocorticoid receptor antagonist therapy in patients with heart failure. Circulation Heart failure. 2014; 7(1):43-50. Epub 2013/11/
    • (2014) Circulation Heart failure , vol.7 , Issue.1 , pp. 43-50
    • Allen, L.A.1    Shetterly, S.M.2    Peterson, P.N.3    Gurwitz, J.H.4    Smith, D.H.5    Brand, D.W.6
  • 39
    • 84926189066 scopus 로고    scopus 로고
    • The relationship between estimated sodium and potassium excretion and subsequent renal outcomes
    • Epub 2014/06/12. PMID: 24918156
    • Smyth A, Dunkler D, Gao P, Teo KK, Yusuf S, O'Donnell MJ, et al. The relationship between estimated sodium and potassium excretion and subsequent renal outcomes. Kidney Int. 2014; 86(6):1205-12. Epub 2014/06/12. doi: 10.1038/ki.2014.214 PMID: 24918156.
    • (2014) Kidney Int. , vol.86 , Issue.6 , pp. 1205-1212
    • Smyth, A.1    Dunkler, D.2    Gao, P.3    Teo, K.K.4    Yusuf, S.5    O'Donnell, M.J.6
  • 40
    • 69749100645 scopus 로고    scopus 로고
    • Predictors of hyperkalemia risk following hypertension control with aldosterone blockade
    • Epub 2009/09/10. PMID: 19738369
    • Khosla N, Kalaitzidis R, Bakris GL. Predictors of hyperkalemia risk following hypertension control with aldosterone blockade. American journal of nephrology. 2009; 30(5):418-24. Epub 2009/09/10. doi: 10. 1159/000237742 PMID: 19738369.
    • (2009) American Journal of Nephrology , vol.30 , Issue.5 , pp. 418-424
    • Khosla, N.1    Kalaitzidis, R.2    Bakris, G.L.3
  • 41
    • 84869417804 scopus 로고    scopus 로고
    • Mineralocorticoid receptor antagonists for heart failure with reduced ejection fraction: Integrating evidence into clinical practice
    • Epub 2012/09/04. PMID: 22942339
    • Zannad F, Gattis Stough W, Rossignol P, Bauersachs J, McMurray JJ, Swedberg K, et al. Mineralocorticoid receptor antagonists for heart failure with reduced ejection fraction: integrating evidence into clinical practice. European heart journal. 2012; 33(22):2782-95. Epub 2012/09/04. doi: 10.1093/eurheartj/ ehs257 PMID: 22942339.
    • (2012) European Heart Journal , vol.33 , Issue.22 , pp. 2782-2795
    • Zannad, F.1    Gattis Stough, W.2    Rossignol, P.3    Bauersachs, J.4    McMurray, J.J.5    Swedberg, K.6
  • 42
    • 79955622277 scopus 로고    scopus 로고
    • Mineralocorticoid receptor activation and blockade: An emerging paradigm in chronic kidney disease
    • Epub 2011/03/18. PMID: 21412221
    • Bertocchio JP, Warnock DG, Jaisser F. Mineralocorticoid receptor activation and blockade: an emerging paradigm in chronic kidney disease. Kidney Int. 2011; 79(10):1051-60. Epub 2011/03/18. doi: 10. 1038/ki.2011.48 PMID: 21412221.
    • (2011) Kidney Int. , vol.79 , Issue.10 , pp. 1051-1060
    • Bertocchio, J.P.1    Warnock, D.G.2    Jaisser, F.3
  • 43
    • 0031819895 scopus 로고    scopus 로고
    • Urinary protein excretion rate is the best independent predictor of ESRF in non-diabetic proteinuric chronic nephropathies
    • Gruppo Italiano di Studi Epidemiologici in Nefrologia (GISEN) Epub 1998/05/09
    • PMID: 9573535Ruggenenti P, Perna A, Mosconi L, Pisoni R, Remuzzi G. Urinary protein excretion rate is the best independent predictor of ESRF in non-diabetic proteinuric chronic nephropathies. "Gruppo Italiano di Studi Epidemiologici in Nefrologia" (GISEN). Kidney Int. 1998; 53(5):1209-16. Epub 1998/05/09. doi: 10. 1046/j.1523-1755.1998.00874.x PMID: 9573535.
    • (1998) Kidney Int , vol.53 , Issue.5 , pp. 1209-1216
    • Ruggenenti, P.1    Perna, A.2    Mosconi, L.3    Pisoni, R.4    Remuzzi, G.5
  • 44
    • 34548029979 scopus 로고    scopus 로고
    • New insights into the pathophysiology of cyclosporine nephrotoxicity: A role of aldosterone
    • Epub 2007/04/13. doi: 00072.2007 [pii] 10.1152/ajprenal.000722007 PMID: 17429034
    • Bobadilla NA, Gamba G. New insights into the pathophysiology of cyclosporine nephrotoxicity: a role of aldosterone. Am J Physiol Renal Physiol. 2007; 293(1):F2-9. Epub 2007/04/13. doi: 00072.2007 [pii] doi: 10.1152/ajprenal.00072.2007 PMID: 17429034.
    • (2007) Am J Physiol Renal Physiol , vol.293 , Issue.1 , pp. F2-F9
    • Bobadilla, N.A.1    Gamba, G.2
  • 45
    • 84894456986 scopus 로고    scopus 로고
    • Smooth muscle cell mineralocorticoid receptors are mandatory for aldosterone-salt to induce vascular stiffness
    • Epub 2013/12/04. PMID: 24296280
    • Galmiche G, Pizard A, Gueret A, El Moghrabi S, Ouvrard-Pascaud A, Berger S, et al. Smooth muscle cell mineralocorticoid receptors are mandatory for aldosterone-salt to induce vascular stiffness. Hypertension. 2014; 63(3):520-6. Epub 2013/12/04. doi: 10.1161/HYPERTENSIONAHA.113.01967 PMID: 24296280.
    • (2014) Hypertension , vol.63 , Issue.3 , pp. 520-526
    • Galmiche, G.1    Pizard, A.2    Gueret, A.3    El Moghrabi, S.4    Ouvrard-Pascaud, A.5    Berger, S.6
  • 46
    • 84893842735 scopus 로고    scopus 로고
    • Spironolactone reduces cardiovascular and cerebrovascular morbidity and mortality in hemodialysis patients
    • Epub 2013/11/05. PMID: 24184249
    • Matsumoto Y, Mori Y, Kageyama S, Arihara K, Sugiyama T, Ohmura H, et al. Spironolactone reduces cardiovascular and cerebrovascular morbidity and mortality in hemodialysis patients. Journal of the American College of Cardiology. 2014; 63(6):528-36. Epub 2013/11/05. doi: 10.1016/j.jacc.2013.09. 056 PMID: 24184249.
    • (2014) Journal of the American College of Cardiology , vol.63 , Issue.6 , pp. 528-536
    • Matsumoto, Y.1    Mori, Y.2    Kageyama, S.3    Arihara, K.4    Sugiyama, T.5    Ohmura, H.6
  • 47
    • 80054975039 scopus 로고    scopus 로고
    • Eplerenone survival benefits in heart failure patients post-myocardial infarction are independent from its diuretic and potassium-sparing effects
    • nsights from an EPHESUS (Eplerenone Post-Acute Myocardial Infarction Heart Failure Efficacy and Survival Study) substudy. Epub 2011/10/29. PMID: 22032706
    • Rossignol P, Menard J, Fay R, Gustafsson F, Pitt B, Zannad F. Eplerenone survival benefits in heart failure patients post-myocardial infarction are independent from its diuretic and potassium-sparing effects. Insights from an EPHESUS (Eplerenone Post-Acute Myocardial Infarction Heart Failure Efficacy and Survival Study) substudy. Journal of the American College of Cardiology. 2011; 58(19):1958-66. Epub 2011/10/29. doi: 10.1016/j.jacc.2011.04.049 PMID: 22032706.
    • (2011) Journal of the American College of Cardiology , vol.58 , Issue.19 , pp. 1958-1966
    • Rossignol, P.1    Menard, J.2    Fay, R.3    Gustafsson, F.4    Pitt, B.5    Zannad, F.6
  • 48
    • 0030587794 scopus 로고    scopus 로고
    • Effectiveness of spironolactone added to an angiotensin-converting enzyme inhibitor and a loop diuretic for severe chronic congestive heart failure (the Randomized Aldactone Evaluation Study [RALES])
    • RALES Epub 1996/10/15. PMID: 8888663
    • RALES. Effectiveness of spironolactone added to an angiotensin-converting enzyme inhibitor and a loop diuretic for severe chronic congestive heart failure (the Randomized Aldactone Evaluation Study [RALES]). The American journal of cardiology. 1996; 78(8):902-7. Epub 1996/10/15. PMID: 8888663.
    • (1996) The American Journal of Cardiology , vol.78 , Issue.8 , pp. 902-907
  • 49
    • 0035997359 scopus 로고    scopus 로고
    • Eplerenone, a selective aldosterone blocker, in mild-to-moderate hypertension
    • Epub 2002/08/06. PMID: 12160194
    • Weinberger MH, Roniker B, Krause SL, Weiss RJ. Eplerenone, a selective aldosterone blocker, in mild-to-moderate hypertension. Am J Hypertens. 2002; 15(8):709-16. Epub 2002/08/06. PMID: 12160194.
    • (2002) Am J Hypertens , vol.15 , Issue.8 , pp. 709-716
    • Weinberger, M.H.1    Roniker, B.2    Krause, S.L.3    Weiss, R.J.4
  • 50
    • 84906557574 scopus 로고    scopus 로고
    • Long-term effects of spironolactone in peritoneal dialysis patients
    • Epub 2013/12/18. PMID: 24335969; PubMed Central PMCID: PMC4005296
    • Ito Y, Mizuno M, Suzuki Y, Tamai H, Hiramatsu T, Ohashi H, et al. Long-term effects of spironolactone in peritoneal dialysis patients. J Am Soc Nephrol. 2014; 25(5):1094-102. Epub 2013/12/18. doi: 10. 1681/ASN.2013030273 PMID: 24335969; PubMed Central PMCID: PMC4005296.
    • (2014) J Am Soc Nephrol , vol.25 , Issue.5 , pp. 1094-1102
    • Ito, Y.1    Mizuno, M.2    Suzuki, Y.3    Tamai, H.4    Hiramatsu, T.5    Ohashi, H.6
  • 51
    • 84920982556 scopus 로고    scopus 로고
    • Patiromer in patients with kidney disease and hyperkalemia receiving RAAS inhibitors
    • Epub 2014/11/22. PMID: 25415805
    • Weir MR, Bakris GL, Bushinsky DA, Mayo MR, Garza D, Stasiv Y, et al. Patiromer in patients with kidney disease and hyperkalemia receiving RAAS inhibitors. N Engl J Med. 2015; 372(3):211-21. Epub 2014/11/22. doi: 10.1056/NEJMoa1410853 PMID: 25415805.
    • (2015) N Engl J Med , vol.372 , Issue.3 , pp. 211-221
    • Weir, M.R.1    Bakris, G.L.2    Bushinsky, D.A.3    Mayo, M.R.4    Garza, D.5    Stasiv, Y.6


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