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Volumn 136, Issue 4, 2017, Pages 328-338

The Inhibitory Effect of Eplerenone on Cell Proliferation in the Contralateral Kidneys of Rats with Unilateral Ureteral Obstruction

Author keywords

Aldosterone; Contralateral kidney; Fibrosis; Inflammation; Mineralocorticoid receptor; Proliferation

Indexed keywords

ALDOSTERONE; COLLAGEN; CYCLINE; EPLERENONE; MESSENGER RNA; MINERALOCORTICOID RECEPTOR; SERUM AND GLUCOCORTICOID REGULATED KINASE 1; ACTIN; IMMEDIATE EARLY PROTEIN; MINERALOCORTICOID ANTAGONIST; PROTEIN SERINE THREONINE KINASE; SERUM-GLUCOCORTICOID REGULATED KINASE; SMOOTH MUSCLE ACTIN, RAT; SPIRONOLACTONE; TUMOR NECROSIS FACTOR;

EID: 85018466087     PISSN: 16608151     EISSN: 22353186     Source Type: Journal    
DOI: 10.1159/000473702     Document Type: Article
Times cited : (19)

References (26)
  • 1
    • 84875620959 scopus 로고    scopus 로고
    • Mechanisms of compensatory renal growth
    • Cleper R: Mechanisms of compensatory renal growth. Pediatr Endocrinol Rev 2012; 10: 152-163.
    • (2012) Pediatr Endocrinol Rev , vol.10 , pp. 152-163
    • Cleper, R.1
  • 2
    • 84943637573 scopus 로고    scopus 로고
    • The fate of nephrons in congenital obstructive nephropathy: Adult recovery is limited by nephron number despite early release of obstruction
    • Sergio M, Galarreta CI, Thornhill BA, Forbes MS, Chevalier RL: The fate of nephrons in congenital obstructive nephropathy: Adult recovery is limited by nephron number despite early release of obstruction. J Urol 2015; 194: 1463-1472.
    • (2015) J Urol , vol.194 , pp. 1463-1472
    • Sergio, M.1    Galarreta, C.I.2    Thornhill, B.A.3    Forbes, M.S.4    Chevalier, R.L.5
  • 3
    • 0021222444 scopus 로고
    • Contralateral renal hyperplasia and increased renal function after relief of chronic unilateral ureteral obstruction
    • Castle WN, Mcdougal WS: Contralateral renal hyperplasia and increased renal function after relief of chronic unilateral ureteral obstruction. J Urol 1984; 132: 1016-1020.
    • (1984) J Urol , vol.132 , pp. 1016-1020
    • Castle, W.N.1    McDougal, W.S.2
  • 4
    • 0015258645 scopus 로고
    • Compensatory hypertrophy of the contralateral kidney after unilateral ureteral ligation
    • Dicker SE, Shirley DG: Compensatory hypertrophy of the contralateral kidney after unilateral ureteral ligation. J Physiol 1972; 220: 199-210.
    • (1972) J Physiol , vol.220 , pp. 199-210
    • Dicker, S.E.1    Shirley, D.G.2
  • 6
    • 84941996305 scopus 로고    scopus 로고
    • The renal effects of mineralocorticoid receptor antagonists
    • Bianchi S, Batini V, Bigazzi R: The renal effects of mineralocorticoid receptor antagonists. Int J Cardiol 2015; 200: 20-24.
    • (2015) Int J Cardiol , vol.200 , pp. 20-24
    • Bianchi, S.1    Batini, V.2    Bigazzi, R.3
  • 7
    • 4544374648 scopus 로고    scopus 로고
    • Prevention of renal fibrosis by spironolactone in mice with complete unilateral ureteral obstruction
    • Trachtman H, Weiser AC, Valderrama E, Morgado M, Palmer LS: Prevention of renal fibrosis by spironolactone in mice with complete unilateral ureteral obstruction. J Urol 2004; 172(4 pt 2):1590-1594.
    • (2004) J Urol , vol.172 , Issue.4 , pp. 1590-1594
    • Trachtman, H.1    Weiser, A.C.2    Valderrama, E.3    Morgado, M.4    Palmer, L.S.5
  • 8
    • 84891130376 scopus 로고    scopus 로고
    • Eplerenone-mediated aldosterone blockade prevents renal fibrosis by reducing renal inflammation, interstitial cell proliferation and oxidative stress
    • Chen H, Sun F, Zhong X, Shao Y, Yoshimura A, Liu Y: Eplerenone-mediated aldosterone blockade prevents renal fibrosis by reducing renal inflammation, interstitial cell proliferation and oxidative stress. Kidney Blood Press Res 2013; 37: 557-566.
    • (2013) Kidney Blood Press Res , vol.37 , pp. 557-566
    • Chen, H.1    Sun, F.2    Zhong, X.3    Shao, Y.4    Yoshimura, A.5    Liu, Y.6
  • 9
    • 84951743062 scopus 로고    scopus 로고
    • Therapeutic targeting of aldosterone: A novel approach to the treatment of glomerular disease
    • Brem AS, Gong R: Therapeutic targeting of aldosterone: A novel approach to the treatment of glomerular disease. Clin Sci (Lond) 2015; 128: 527-535.
    • (2015) Clin Sci (Lond) , vol.128 , pp. 527-535
    • Brem, A.S.1    Gong, R.2
  • 10
    • 84925445398 scopus 로고    scopus 로고
    • Urinary candidate biomarker discovery in a rat unilateral ureteral obstruction model
    • Yuan Y, Zhang F, Wu J, Shao C, Gao Y: Urinary candidate biomarker discovery in a rat unilateral ureteral obstruction model. Sci Rep 2015; 5: 9314.
    • (2015) Sci Rep , vol.5 , pp. 9314
    • Yuan, Y.1    Zhang, F.2    Wu, J.3    Shao, C.4    Gao, Y.5
  • 11
    • 84960961240 scopus 로고    scopus 로고
    • Inhibition of spleen tyrosine kinase (syk) suppresses renal fibrosis through anti-inflammatory effects and down regulation of the MAPK-p38 pathway
    • Chen KH, Hsu HH, Yang HY, Tian YC, Ko YC, Yang CW, Hung CC: Inhibition of spleen tyrosine kinase (syk) suppresses renal fibrosis through anti-inflammatory effects and down regulation of the MAPK-p38 pathway. Int J Biochem Cell Biol 2016; 74: 135-144.
    • (2016) Int J Biochem Cell Biol , vol.74 , pp. 135-144
    • Chen, K.H.1    Hsu, H.H.2    Yang, H.Y.3    Tian, Y.C.4    Ko, Y.C.5    Yang, C.W.6    Hung, C.C.7
  • 12
    • 85018193591 scopus 로고    scopus 로고
    • Salvianolic acid A as a multifunctional agent ameliorates doxorubicin-induced nephropathy in rats
    • Fan HY, Yang MY, Qi D, et al: Salvianolic acid A as a multifunctional agent ameliorates doxorubicin-induced nephropathy in rats. Sci Rep 2015; 5: 12273.
    • (2015) Sci Rep , vol.5 , pp. 12273
    • Fan, H.Y.1    Yang, M.Y.2    Qi, D.3
  • 13
    • 0029791507 scopus 로고    scopus 로고
    • Renal hemodynamic response to ureteral obstruction during converting enzyme inhibition
    • Frokiaer J, Djurhuus JC, Nielsen M, Pedersen EB: Renal hemodynamic response to ureteral obstruction during converting enzyme inhibition. Urol Res 1996; 24: 217-227.
    • (1996) Urol Res , vol.24 , pp. 217-227
    • Frokiaer, J.1    Djurhuus, J.C.2    Nielsen, M.3    Pedersen, E.B.4
  • 14
    • 84894593599 scopus 로고    scopus 로고
    • Molecular mechanisms of epithelial-mesenchymal transition
    • Lamouille S, Xu J, Derynck R: Molecular mechanisms of epithelial-mesenchymal transition. Nat Rev Mol Cell Biol 2014; 15: 178-196.
    • (2014) Nat Rev Mol Cell Biol , vol.15 , pp. 178-196
    • Lamouille, S.1    Xu, J.2    Derynck, R.3
  • 15
    • 84938505204 scopus 로고    scopus 로고
    • Aldosterone-induced cardiomyocyte growth, and fibroblast migration and proliferation are mediated by TRAF3IP2
    • Somanna NK, Yariswamy M, Garagliano JM, et al: Aldosterone-induced cardiomyocyte growth, and fibroblast migration and proliferation are mediated by TRAF3IP2. Cell Signal 2015; 27: 1928-1938.
    • (2015) Cell Signal , vol.27 , pp. 1928-1938
    • Somanna, N.K.1    Yariswamy, M.2    Garagliano, J.M.3
  • 16
    • 84880687429 scopus 로고    scopus 로고
    • Rho kinase pathway is likely responsible for the profibrotic actions of aldosterone in renal epithelial cells via inducing epithelial-mesenchymal transition and extracellular matrix excretion
    • Wei J, Li Z, Ma C, et al: Rho kinase pathway is likely responsible for the profibrotic actions of aldosterone in renal epithelial cells via inducing epithelial-mesenchymal transition and extracellular matrix excretion. Cell Biol Int 2013; 37: 725-730.
    • (2013) Cell Biol Int , vol.37 , pp. 725-730
    • Wei, J.1    Li, Z.2    Ma, C.3
  • 17
    • 84933529443 scopus 로고    scopus 로고
    • Anti-albuminuric effect of the aldosterone blocker eplerenone in non-diabetic hypertensive patients with albuminuria: A double-blind, randomised, placebo-controlled trial
    • Ando K, Ohtsu H, Uchida S, et al: Anti-albuminuric effect of the aldosterone blocker eplerenone in non-diabetic hypertensive patients with albuminuria: A double-blind, randomised, placebo-controlled trial. Lancet Diabetes Endocrinol 2014; 2: 944-953.
    • (2014) Lancet Diabetes Endocrinol , vol.2 , pp. 944-953
    • Ando, K.1    Ohtsu, H.2    Uchida, S.3
  • 18
    • 84906092409 scopus 로고    scopus 로고
    • Mechanism of salt-sensitive hypertension: Focus on adrenal and sympathetic nervous systems
    • Fujita T: Mechanism of salt-sensitive hypertension: Focus on adrenal and sympathetic nervous systems. J Am Soc Nephrol 2014; 25: 1148-1155.
    • (2014) J Am Soc Nephrol , vol.25 , pp. 1148-1155
    • Fujita, T.1
  • 20
    • 84930836819 scopus 로고    scopus 로고
    • SGK1 inhibits cellular apoptosis and promotes proliferation via the MEK/ERK/p53 pathway in colitis
    • Bai JA, Xu GF, Yan LJ, Zeng WW, Ji QQ, Wu JD, Tang QY: SGK1 inhibits cellular apoptosis and promotes proliferation via the MEK/ERK/p53 pathway in colitis. World J Gastroenterol 2015; 21: 6180-6193.
    • (2015) World J Gastroenterol , vol.21 , pp. 6180-6193
    • Bai, J.A.1    Xu, G.F.2    Yan, L.J.3    Zeng, W.W.4    Ji, Q.Q.5    Wu, J.D.6    Tang, Q.Y.7
  • 21
    • 84994860289 scopus 로고    scopus 로고
    • Epidermal growth factor receptor signaling mediates aldosterone-induced profibrotic responses in kidney
    • Sheng L, Yang M, Ding W, et al: Epidermal growth factor receptor signaling mediates aldosterone-induced profibrotic responses in kidney. Exp Cell Res 2016; 346: 99-110.
    • (2016) Exp Cell Res , vol.346 , pp. 99-110
    • Sheng, L.1    Yang, M.2    Ding, W.3
  • 22
    • 0033392921 scopus 로고    scopus 로고
    • Cyclin kinase inhibitor p21CIP1/WAF1 limits interstitial cell proliferation following ureteric obstruction
    • Hughes J, Brown P, Shankland SJ: Cyclin kinase inhibitor p21CIP1/WAF1 limits interstitial cell proliferation following ureteric obstruction. Am J Physiol 1999; 277(6 pt 2): F948-F956.
    • (1999) Am J Physiol , vol.277 , Issue.6 , pp. F948-F956
    • Hughes, J.1    Brown, P.2    Shankland, S.J.3
  • 23
    • 0025740728 scopus 로고
    • Disturbance in sodium regulating hormones in chronic obstructive uropathy
    • Clarke NW, Jones DA, Tames F, Laing I, George NJ: Disturbance in sodium regulating hormones in chronic obstructive uropathy. Br J Urol 1991; 68: 118-121.
    • (1991) Br J Urol , vol.68 , pp. 118-121
    • Clarke, N.W.1    Jones, D.A.2    Tames, F.3    Laing, I.4    George, N.J.5
  • 24
    • 34548040691 scopus 로고    scopus 로고
    • Altered expression of epithelial sodium channel in rats with bilateral or unilateral ureteral obstruction
    • Li C, Wang W, Norregaard R, Knepper MA, Nielsen S, Frokiaer J: Altered expression of epithelial sodium channel in rats with bilateral or unilateral ureteral obstruction. Am J Physiol Renal Physiol 2007; 293:F333-F341.
    • (2007) Am J Physiol Renal Physiol , vol.293 , pp. F333-F341
    • Li, C.1    Wang, W.2    Norregaard, R.3    Knepper, M.A.4    Nielsen, S.5    Frokiaer, J.6
  • 25
    • 85017435757 scopus 로고    scopus 로고
    • Effects of exendin-4 on the intrarenal renin-angiotensin system and interstitial fibrosis in unilateral ureteral obstruction mice: Exendin-4 and unilateral ureteral obstruction
    • 1470320316677918
    • Le Y, Zheng Z, Xue J, et al: Effects of exendin-4 on the intrarenal renin-angiotensin system and interstitial fibrosis in unilateral ureteral obstruction mice: Exendin-4 and unilateral ureteral obstruction. J Renin Angiotensin Aldosterone Syst 2016;-pii:1470320316677918.
    • (2016) J Renin Angiotensin Aldosterone Syst
    • Le, Y.1    Zheng, Z.2    Xue, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.