Spironolactone suppresses inflammation and prevents L-NAME-induced renal injury in rats

Kidney International

Volumn 75, Issue 2, 2009, Pages 147-155

  Ikeda, Hirofumi ^a   Tsuruya, Kazuhiko ^a   Toyonaga, Jiro ^a   Masutani, Kohsuke ^a   Hayashida, Hideko ^a   Hirakata, Hideki ^a   Iida, Mitsuo ^a  

^a KYUSHU UNIVERSITY   (Japan)

Author keywords

Aldosterone; Interstitial fibrosis; Nitric oxide; Osteopontin; Renin angiotensin system

Indexed keywords

ALDOSTERONE; ALPHA SMOOTH MUSCLE ACTIN; CREATININE; HYDRALAZINE; N(G) NITROARGININE METHYL ESTER; OSTEOPONTIN; SPIRONOLACTONE; TRANSFORMING GROWTH FACTOR BETA1;

ALDOSTERONE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DRUG EFFECT; FIBROSING ALVEOLITIS; GLOMERULOSCLEROSIS; HISTOPATHOLOGY; KIDNEY INJURY; MALE; NEPHRITIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SYSTOLIC BLOOD PRESSURE; URINARY EXCRETION;

ANIMALS; FIBROSIS; HEMODYNAMICS; INFLAMMATION; KIDNEY DISEASES; MALE; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; OSTEOPONTIN; PROTECTIVE AGENTS; RATS; RATS, WISTAR; RECEPTORS, ALDOSTERONE; RNA, MESSENGER; SPIRONOLACTONE;

EID: 58149145611     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/ki.2008.507     Document Type: Article

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