Addition of spironolactone to dual blockade of renin angiotensin system dramatically reduces severe proteinuria in renal transplant patients: An uncontrolled pilot study at 6 months

Transplantation Proceedings

Volumn 42, Issue 8, 2010, Pages 2899-2901

  Gonzalez Monte, E ^a   Andres, A ^a   Polanco, N ^a   Toribio, M J ^a   Santana, R ^a   Gutierrez Martinez E ^a   Gonzalez, J ^a   Ramirez, E ^a   Hernandez, A ^a   Morales, E ^a   Praga, M ^a   Morales, J M ^a  

^a HOSPITAL UNIVERSITARIO 12 DE OCTUBRE   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN RECEPTOR ANTAGONIST; CREATININE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; SPIRONOLACTONE;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CREATININE BLOOD LEVEL; DISEASE SEVERITY; FEMALE; GLOMERULUS FILTRATION RATE; GRAFT RECIPIENT; HUMAN; HYPERKALEMIA; KIDNEY FUNCTION; KIDNEY TRANSPLANTATION; MALE; PILOT STUDY; PRIORITY JOURNAL; PROTEINURIA; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; TREATMENT INDICATION;

ADULT; ALDOSTERONE ANTAGONISTS; ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; COMBINED MODALITY THERAPY; FEMALE; FOLLOW-UP STUDIES; HUMANS; KIDNEY TRANSPLANTATION; MALE; MIDDLE AGED; PILOT PROJECTS; PROTEINURIA; RENIN-ANGIOTENSIN SYSTEM; SPIRONOLACTONE;

EID: 77958533631     PISSN: 00411345     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.transproceed.2010.08.024     Document Type: Article

References (5)

1. J.I. Roodnat, P.G. Mulder, and J. Rischen-Vos Proteinuria after renal transplantation affects not only graft survival but also patient survival Transplantation 72 2001 438
2. G. Fernandez-Fresnedo, J.J. Plaza, and J. Sánchez-Plumed Proteinuria: a new marker of long-term graft and patient survival in kidney transplantation Nephrol Dial Transplant 19 2004 47
3. S. Hiremath, D. Fergusson, and S. Doucette Renin angiotensin system blockade in kidney transplantation: a systematic review of the evidence Am J Transplant 7 2007 2350
4. A. Chrysostomou, E. Pedagogos, and L. MacGregor Double-blind, placebo-controlled study on the effect of the aldosterone receptor antagonist spironolactone in patients who have persistent proteinuria and are on long-term angiotensin-converting enzyme inhibitor therapy, with or without an angiotensin II receptor blocker Clin J Am Soc Nephrol 1 2006 256
5. S. Bianchi, R. Bigazzi, and V.M. Campese Long-term effects of spironolactone on proteinuria and kidney function in patients with chronic kidney disease Kidney Int 70 2006 2051