Mineralocorticoid receptor-mediated DNA damage in kidneys of DOCA-salt hypertensive rats

FASEB Journal

Volumn 25, Issue 3, 2011, Pages 968-978

  Schupp, Nicole ^a   Kolkhof, Peter ^b   Queisser, Nina ^a   Gärtner, Sabine ^a   Schmid, Ursula ^a   Kretschmer, Axel ^b   Hartmann, Elke ^b   Oli, Rajaraman G ^a   Schäfer, Stefan ^b,c   Stopper, Helga ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b BAYER PHARMA AG   (Germany)

^c SYNTHON BV   (Netherlands)

Author keywords

8 oxodG; Double strand breaks; Hypertension; Oxidative DNA damage; Oxidative stress

Indexed keywords

8 HYDROXYGUANINE; DEOXYCORTICOSTERONE ACETATE; DNA BASE; MINERALOCORTICOID RECEPTOR; MONOCYTE CHEMOTACTIC PROTEIN 1; SPIRONOLACTONE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BLOOD PRESSURE; CELL PROLIFERATION; DNA DAMAGE; DOUBLE STRANDED DNA BREAK; HYPERTENSION; IC 50; IMMUNOHISTOCHEMISTRY; KIDNEY FAILURE; LIQUID CHROMATOGRAPHY; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; TANDEM MASS SPECTROMETRY;

ALDOSTERONE ANTAGONISTS; ANIMALS; APOPTOSIS; BLOOD PRESSURE; CELL DIVISION; DESOXYCORTICOSTERONE; DISEASE MODELS, ANIMAL; DNA BREAKS, DOUBLE-STRANDED; DNA DAMAGE; GUANINE; HYPERTENSION, RENAL; KIDNEY; MALE; MINERALOCORTICOIDS; NEPHRECTOMY; NEPHRITIS; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, MINERALOCORTICOID; SPIRONOLACTONE;

RATTUS;

EID: 79954571357     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.10-173286     Document Type: Article

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