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Volumn 17, Issue 1, 2016, Pages

Effect of mineralocorticoid receptor antagonists on proteinuria and progression of chronic kidney disease: A systematic review and meta-analysis

(17)  Currie, Gemma a   Taylor, Alison H M a   Fujita, Toshiro b   Ohtsu, Hiroshi c   Lindhardt, Morten d   Rossing, Peter d,e,f   Boesby, Lene f   Edwards, Nicola C g   Ferro, Charles J g   Townend, Jonathan N g   Van Den Meiracker, Anton H h   Saklayen, Mohammad G i   Oveisi, Sonia j   Jardine, Alan G a   Delles, Christian a   Preiss, David J k   Mark, Patrick B a  


Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN; EPLERENONE; MINERALOCORTICOID ANTAGONIST; POTASSIUM; SPIRONOLACTONE; ANGIOTENSIN RECEPTOR ANTAGONIST; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR;

EID: 84992176768     PISSN: None     EISSN: 14712369     Source Type: Journal    
DOI: 10.1186/s12882-016-0337-0     Document Type: Review
Times cited : (137)

References (57)
  • 1
    • 0037228105 scopus 로고    scopus 로고
    • Prevalence of chronic kidney disease and decreased kidney function in the adult US population: Third National Health and Nutrition Examination Survey
    • 12500213
    • Coresh J, Astor BC, Greene T, Eknoyan G, Levey AS. Prevalence of chronic kidney disease and decreased kidney function in the adult US population: Third National Health and Nutrition Examination Survey. Am J Kidney Dis. 2003;41:1-12.
    • (2003) Am J Kidney Dis , vol.41 , pp. 1-12
    • Coresh, J.1    Astor, B.C.2    Greene, T.3    Eknoyan, G.4    Levey, A.S.5
  • 3
    • 4644221457 scopus 로고    scopus 로고
    • Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization
    • 1:CAS:528:DC%2BD2cXnvFSgtr8%3D 15385656
    • Go AS, Chertow GM, Fan D, McCulloch CE, Hsu CY. Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization. N Engl J Med. 2004;351:1296-305.
    • (2004) N Engl J Med , vol.351 , pp. 1296-1305
    • Go, A.S.1    Chertow, G.M.2    Fan, D.3    McCulloch, C.E.4    Hsu, C.Y.5
  • 4
    • 34047124964 scopus 로고    scopus 로고
    • Kidney disease and cardiovascular risk
    • 1:CAS:528:DC%2BD2sXisV2jsbw%3D 17081079
    • Tonelli M, Pfeffer MA. Kidney disease and cardiovascular risk. Annu Rev Med. 2007;58:123-39.
    • (2007) Annu Rev Med , vol.58 , pp. 123-139
    • Tonelli, M.1    Pfeffer, M.A.2
  • 5
    • 35848968871 scopus 로고    scopus 로고
    • Prevalence of chronic kidney disease in the United States
    • 1:CAS:528:DC%2BD2sXht1yjsLnM 17986697
    • Coresh J, Selvin E, Stevens LA, Manzi J, Kusek JW, Eggers P, et al. Prevalence of chronic kidney disease in the United States. JAMA. 2007;298:2038-47.
    • (2007) JAMA , vol.298 , pp. 2038-2047
    • Coresh, J.1    Selvin, E.2    Stevens, L.A.3    Manzi, J.4    Kusek, J.W.5    Eggers, P.6
  • 6
    • 34648825832 scopus 로고    scopus 로고
    • End-stage renal disease and economic incentives: The International Study of Health Care Organization and Financing (ISHCOF)
    • 17653860
    • Dor A, Pauly MV, Eichleay MA, Held PJ. End-stage renal disease and economic incentives: the International Study of Health Care Organization and Financing (ISHCOF). Int J Health Care Finance Econ. 2007;7:73-111.
    • (2007) Int J Health Care Finance Econ , vol.7 , pp. 73-111
    • Dor, A.1    Pauly, M.V.2    Eichleay, M.A.3    Held, P.J.4
  • 7
    • 84862580467 scopus 로고    scopus 로고
    • Urinary corticosteroid excretion predicts left ventricular mass and proteinuria in chronic kidney disease
    • 1:CAS:528:DC%2BC38Xhs1WqurrJ
    • McQuarrie EP, Freel EM, Mark PB, Fraser R, Patel RK, Dargie HG, et al. Urinary corticosteroid excretion predicts left ventricular mass and proteinuria in chronic kidney disease. Clin Sci (Lond). 2012;123:285-94.
    • (2012) Clin Sci (Lond) , vol.123 , pp. 285-294
    • McQuarrie, E.P.1    Freel, E.M.2    Mark, P.B.3    Fraser, R.4    Patel, R.K.5    Dargie, H.G.6
  • 8
    • 0035922441 scopus 로고    scopus 로고
    • Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy
    • 1:CAS:528:DC%2BD3MXntlelsLk%3D 11565518
    • Brenner BM, Cooper ME, de ZD, Keane WF, Mitch WE, Parving HH, et al. Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy. N Engl J Med. 2001;345:861-9.
    • (2001) N Engl J Med , vol.345 , pp. 861-869
    • Brenner, B.M.1    Cooper, M.E.2    De, Z.D.3    Keane, W.F.4    Mitch, W.E.5    Parving, H.H.6
  • 9
    • 0035902622 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme inhibitors and progression of nondiabetic renal disease. A meta-analysis of patient-level data
    • 1:CAS:528:DC%2BD3MXlslSlsrY%3D 11453706
    • Jafar TH, Schmid CH, Landa M, Giatras I, Toto R, Remuzzi G, et al. Angiotensin-converting enzyme inhibitors and progression of nondiabetic renal disease. A meta-analysis of patient-level data. Ann Intern Med. 2001;135:73-87.
    • (2001) Ann Intern Med , vol.135 , pp. 73-87
    • Jafar, T.H.1    Schmid, C.H.2    Landa, M.3    Giatras, I.4    Toto, R.5    Remuzzi, G.6
  • 10
    • 0141789624 scopus 로고    scopus 로고
    • Progression of chronic kidney disease: The role of blood pressure control, proteinuria, and angiotensin-converting enzyme inhibition: A patient-level meta-analysis
    • 1:CAS:528:DC%2BD3sXnt12kurs%3D 12965979
    • Jafar TH, Stark PC, Schmid CH, Landa M, Maschio G, de Jong PE, et al. Progression of chronic kidney disease: the role of blood pressure control, proteinuria, and angiotensin-converting enzyme inhibition: a patient-level meta-analysis. Ann Intern Med. 2003;139:244-52.
    • (2003) Ann Intern Med , vol.139 , pp. 244-252
    • Jafar, T.H.1    Stark, P.C.2    Schmid, C.H.3    Landa, M.4    Maschio, G.5    De Jong, P.E.6
  • 11
    • 84878598114 scopus 로고    scopus 로고
    • KDIGO 2012 clinical practice guideline for evaluation and management of chronic kidney disease
    • KDIGO
    • KDIGO. KDIGO 2012 clinical practice guideline for evaluation and management of chronic kidney disease. Kidney International Supplements. 2013;3:73-90.
    • (2013) Kidney International Supplements , vol.3 , pp. 73-90
  • 13
    • 42749099562 scopus 로고    scopus 로고
    • Angiotensin converting ensyme inhibitors and angiotensin II receptor antagonists for preventing the progression of diabetic kidney disease
    • 20-10-2014
    • Strippoli GF, Bonifati C, Craig M, Navaneethan SD, Craig JC. Angiotensin converting ensyme inhibitors and angiotensin II receptor antagonists for preventing the progression of diabetic kidney disease. Cochrane Database of Systematic Reviews Issue 4. 2014. 20-10-2014
    • (2014) Cochrane Database of Systematic Reviews , Issue.4
    • Strippoli, G.F.1    Bonifati, C.2    Craig, M.3    Navaneethan, S.D.4    Craig, J.C.5
  • 14
    • 0030604561 scopus 로고    scopus 로고
    • Randomised placebo-controlled trial of effect of ramipril on decline in glomerular filtration rate and risk of terminal renal failure in proteinuric, non-diabetic nephropathy
    • The GISEN Group (Gruppo Italiano di Studi Epidemiologici in Nefrologia)
    • Randomised placebo-controlled trial of effect of ramipril on decline in glomerular filtration rate and risk of terminal renal failure in proteinuric, non-diabetic nephropathy. The GISEN Group (Gruppo Italiano di Studi Epidemiologici in Nefrologia). Lancet. 1997;349:1857-63
    • (1997) Lancet. , vol.349 , pp. 1857-1863
  • 15
    • 66149131479 scopus 로고    scopus 로고
    • Aldosterone antagonists for preventing the progression of chronic kidney disease: A systematic review and meta-analysis
    • 1:CAS:528:DC%2BD1MXktFKis78%3D 19261819 2653663
    • Navaneethan SD, Nigwekar SU, Sehgal AR, Strippoli GF. Aldosterone antagonists for preventing the progression of chronic kidney disease: a systematic review and meta-analysis. Clin J Am Soc Nephrol. 2009;4:542-51.
    • (2009) Clin J Am Soc Nephrol , vol.4 , pp. 542-551
    • Navaneethan, S.D.1    Nigwekar, S.U.2    Sehgal, A.R.3    Strippoli, G.F.4
  • 17
    • 73549091271 scopus 로고    scopus 로고
    • Hyperkalemia risk in chronic kidney disease: Deterrent to the use of aldosterone receptor antagonism or not
    • 1:CAS:528:DC%2BD1MXls1Sktrk%3D 19307465
    • Sica DA. Hyperkalemia risk in chronic kidney disease: deterrent to the use of aldosterone receptor antagonism or not. Hypertension. 2009;53:749-50.
    • (2009) Hypertension , vol.53 , pp. 749-750
    • Sica, D.A.1
  • 18
    • 60549113949 scopus 로고    scopus 로고
    • Hyperkalemia as a constraint to therapy with combination Renin-Angiotensin system blockade: The elephant in the room
    • Epstein M. Hyperkalemia as a constraint to therapy with combination Renin-Angiotensin system blockade: the elephant in the room. J Clin Hypertens (Greenwich). 2009;11:55-60.
    • (2009) J Clin Hypertens (Greenwich) , vol.11 , pp. 55-60
    • Epstein, M.1
  • 19
    • 72049093965 scopus 로고    scopus 로고
    • Mechanisms of impaired potassium handling with dual renin-angiotensin-aldosterone blockade in chronic kidney disease
    • 1:CAS:528:DC%2BD1MXksFeitrk%3D 19307466
    • Preston RA, Afshartous D, Garg D, Medrano S, Alonso AB, Rodriguez R. Mechanisms of impaired potassium handling with dual renin-angiotensin-aldosterone blockade in chronic kidney disease. Hypertension. 2009;53:754-60.
    • (2009) Hypertension , vol.53 , pp. 754-760
    • Preston, R.A.1    Afshartous, D.2    Garg, D.3    Medrano, S.4    Alonso, A.B.5    Rodriguez, R.6
  • 20
    • 84950323726 scopus 로고    scopus 로고
    • Cardiovascular actions of mineralocorticoid receptor antagonists in patients with chronic kidney disease: A systematic review and meta-analysis
    • 1:CAS:528:DC%2BC28Xns1Gqsb8%3D 25784710
    • Ng K, Arnold J, Sharif A, Gill P, Townend J, Ferro C. Cardiovascular actions of mineralocorticoid receptor antagonists in patients with chronic kidney disease: a systematic review and meta-analysis. J Renin Angiotensin Aldosterone Syst. 2015;16:599-613.
    • (2015) J Renin Angiotensin Aldosterone Syst , vol.16 , pp. 599-613
    • Ng, K.1    Arnold, J.2    Sharif, A.3    Gill, P.4    Townend, J.5    Ferro, C.6
  • 22
    • 72049109463 scopus 로고    scopus 로고
    • Addition of angiotensin receptor blockade or mineralocorticoid antagonism to maximal angiotensin-converting enzyme inhibition in diabetic nephropathy
    • 1:CAS:528:DC%2BD1MXhs1Witb3P 19926893 2794224
    • Mehdi UF, Adams-Huet B, Raskin P, Vega GL, Toto RD. Addition of angiotensin receptor blockade or mineralocorticoid antagonism to maximal angiotensin-converting enzyme inhibition in diabetic nephropathy. J Am Soc Nephrol. 2009;20:2641-50.
    • (2009) J Am Soc Nephrol , vol.20 , pp. 2641-2650
    • Mehdi, U.F.1    Adams-Huet, B.2    Raskin, P.3    Vega, G.L.4    Toto, R.D.5
  • 23
    • 67651048925 scopus 로고    scopus 로고
    • Effect of spironolactone on left ventricular mass and aortic stiffness in early-stage chronic kidney disease: A randomized controlled trial
    • 1:CAS:528:DC%2BD1MXhtFaisLfP 19643310
    • Edwards NC, Steeds RP, Stewart PM, Ferro CJ, Townend JN. Effect of spironolactone on left ventricular mass and aortic stiffness in early-stage chronic kidney disease: a randomized controlled trial. J Am Coll Cardiol. 2009;54:505-12.
    • (2009) J Am Coll Cardiol , vol.54 , pp. 505-512
    • Edwards, N.C.1    Steeds, R.P.2    Stewart, P.M.3    Ferro, C.J.4    Townend, J.N.5
  • 24
    • 79952220553 scopus 로고    scopus 로고
    • Efficacy of low dose spironolactone in chronic kidney disease with resistant hypertension
    • 21196617
    • Abolghasmi R, Taziki O. Efficacy of low dose spironolactone in chronic kidney disease with resistant hypertension. Saudi J Kidney Dis Transpl. 2011;22:75-8.
    • (2011) Saudi J Kidney Dis Transpl , vol.22 , pp. 75-78
    • Abolghasmi, R.1    Taziki, O.2
  • 25
    • 71049132261 scopus 로고    scopus 로고
    • Antifibrotic effects of aldosterone receptor blocker (spironolactone) in patients with chronic kidney disease
    • 1:CAS:528:DC%2BD1MXhsVClu7vJ 19925284
    • Guney I, Selcuk NY, Altintepe L, Atalay H, Basarali MK, Buyukbas S. Antifibrotic effects of aldosterone receptor blocker (spironolactone) in patients with chronic kidney disease. Ren Fail. 2009;31:779-84.
    • (2009) Ren Fail , vol.31 , pp. 779-784
    • Guney, I.1    Selcuk, N.Y.2    Altintepe, L.3    Atalay, H.4    Basarali, M.K.5    Buyukbas, S.6
  • 26
    • 84864023693 scopus 로고    scopus 로고
    • Spironolactone diminishes urinary albumin excretion in patients with type 1 diabetes and microalbuminuria: A randomized placebo-controlled crossover study
    • 1:STN:280:DC%2BC38vgvFKitA%3D%3D 22268920
    • Nielsen S, Perrson F, Frandsen E, Sugaya T, Hess G, Zdunek D, et al. Spironolactone diminishes urinary albumin excretion in patients with type 1 diabetes and microalbuminuria: a randomized placebo-controlled crossover study. Diabet Med. 2012;29:e184-90.
    • (2012) Diabet Med , vol.29 , pp. e184-e190
    • Nielsen, S.1    Perrson, F.2    Frandsen, E.3    Sugaya, T.4    Hess, G.5    Zdunek, D.6
  • 27
    • 84878982045 scopus 로고    scopus 로고
    • Effects of additive therapy with spironolactone on albuminuria in diabetes mellitus: A pilot randomized clinical trial
    • 1:CAS:528:DC%2BC3sXpt1Churo%3D 24009953 3755820
    • Ziaee A, Abbas VA, Oveisi S, Javadi A, Hashemipour S, Kazemifar AM. Effects of additive therapy with spironolactone on albuminuria in diabetes mellitus: a pilot randomized clinical trial. Caspian J Intern Med. 2013;4:648-53.
    • (2013) Caspian J Intern Med , vol.4 , pp. 648-653
    • Ziaee, A.1    Abbas, V.A.2    Oveisi, S.3    Javadi, A.4    Hashemipour, S.5    Kazemifar, A.M.6
  • 28
    • 84933529443 scopus 로고    scopus 로고
    • Anti-albuminuric effect of the aldosterone blocker eplerenone in non-diabetic hypertensive patients with albuminuria: A double-blind, randomised, placebo-controlled trial
    • 1:CAS:528:DC%2BC2MXksF2gt7c%3D 25466242
    • Ando K, Ohtsu H, Uchida S, Kaname S, Arakawa Y, Fujita T. Anti-albuminuric effect of the aldosterone blocker eplerenone in non-diabetic hypertensive patients with albuminuria: a double-blind, randomised, placebo-controlled trial. Lancet Diabetes Endocrinol. 2014;2:944-53.
    • (2014) Lancet Diabetes Endocrinol , vol.2 , pp. 944-953
    • Ando, K.1    Ohtsu, H.2    Uchida, S.3    Kaname, S.4    Arakawa, Y.5    Fujita, T.6
  • 29
    • 80455145142 scopus 로고    scopus 로고
    • Moderate antiproteinuric effect of add-on aldosterone blockade with eplerenone in non-diabetic chronic kidney disease. A randomized cross-over study
    • 1:CAS:528:DC%2BC3MXhsFaqu7zL 22073219 3208556
    • Boesby L, Elung-Jensen T, Klausen TW, Strandgaard S, Kamper AL. Moderate antiproteinuric effect of add-on aldosterone blockade with eplerenone in non-diabetic chronic kidney disease. A randomized cross-over study. PLoS One. 2011;6:e26904.
    • (2011) PLoS One , vol.6 , pp. e26904
    • Boesby, L.1    Elung-Jensen, T.2    Klausen, T.W.3    Strandgaard, S.4    Kamper, A.L.5
  • 30
    • 84877969830 scopus 로고    scopus 로고
    • Eplerenone attenuates pulse wave reflection in chronic kidney disease stage 3-4-a randomized controlled study
    • 1:CAS:528:DC%2BC3sXovVKgsro%3D 23704994 3660355
    • Boesby L, Elung-Jensen T, Strandgaard S, Kamper AL. Eplerenone attenuates pulse wave reflection in chronic kidney disease stage 3-4-a randomized controlled study. PLoS One. 2013;8:e64549.
    • (2013) PLoS One , vol.8 , pp. e64549
    • Boesby, L.1    Elung-Jensen, T.2    Strandgaard, S.3    Kamper, A.L.4
  • 31
    • 84870757645 scopus 로고    scopus 로고
    • The enhanced renin-angiotensin-aldosteron system pharmacological blockade-which is the best?
    • 1:CAS:528:DC%2BC3sXktF2rsr8%3D 23235363
    • Tylicki L, Lizakowski S, Rutkowski P, Renke M, Sulikowska B, Heleniak Z, et al. The enhanced renin-angiotensin-aldosteron system pharmacological blockade-which is the best? Kidney Blood Press Res. 2012;36:335-43.
    • (2012) Kidney Blood Press Res , vol.36 , pp. 335-343
    • Tylicki, L.1    Lizakowski, S.2    Rutkowski, P.3    Renke, M.4    Sulikowska, B.5    Heleniak, Z.6
  • 32
    • 84862697216 scopus 로고    scopus 로고
    • A prospective double-blind randomized placebo-controlled clinical trial to evaluate the safety and efficacy of spironolactone in patients with advanced congestive heart failure on continuous ambulatory peritoneal dialysis
    • 22569436
    • Taheri S, Mortazavi M, Pourmoghadas A, Seyrafian S, Alipour Z, Karimi S. A prospective double-blind randomized placebo-controlled clinical trial to evaluate the safety and efficacy of spironolactone in patients with advanced congestive heart failure on continuous ambulatory peritoneal dialysis. Saudi J Kidney Dis Transpl. 2012;23:507-12.
    • (2012) Saudi J Kidney Dis Transpl , vol.23 , pp. 507-512
    • Taheri, S.1    Mortazavi, M.2    Pourmoghadas, A.3    Seyrafian, S.4    Alipour, Z.5    Karimi, S.6
  • 33
    • 77955728969 scopus 로고    scopus 로고
    • A randomized, double-blind, placebo-controlled trial of spironolactone on carotid intima-media thickness in nondiabetic hemodialysis patients
    • 1:CAS:528:DC%2BC3cXhtFCru7nJ 20522535 2924413
    • Vukusich A, Kunstmann S, Varela C, Gainza D, Bravo S, Sepulveda D, et al. A randomized, double-blind, placebo-controlled trial of spironolactone on carotid intima-media thickness in nondiabetic hemodialysis patients. Clin J Am Soc Nephrol. 2010;5:1380-7.
    • (2010) Clin J Am Soc Nephrol , vol.5 , pp. 1380-1387
    • Vukusich, A.1    Kunstmann, S.2    Varela, C.3    Gainza, D.4    Bravo, S.5    Sepulveda, D.6
  • 34
    • 84888417195 scopus 로고    scopus 로고
    • Effect of spironolactone combined with angiotensin converting enzyme inhibitors and/or angiotensin II receptor blockers on chronic glomerular disease
    • 1:CAS:528:DC%2BC3sXhvFOms7zM 24255685 3829763
    • Wang W, Li L, Zhou Z, Gao J, Sun Y. Effect of spironolactone combined with angiotensin converting enzyme inhibitors and/or angiotensin II receptor blockers on chronic glomerular disease. Experimental and Therapeutic Medicine. 2013;6:1527-31.
    • (2013) Experimental and Therapeutic Medicine , vol.6 , pp. 1527-1531
    • Wang, W.1    Li, L.2    Zhou, Z.3    Gao, J.4    Sun, Y.5
  • 35
    • 84859001212 scopus 로고    scopus 로고
    • The Cochrane Collaboration's tool for assessing risk of bias in randomised trials
    • 22008217 3196245
    • Higgins JP, Altman DG, Gotzsche PC, Juni P, Moher D, Oxman AD, et al. The Cochrane Collaboration's tool for assessing risk of bias in randomised trials. BMJ. 2011;343:d5928.
    • (2011) BMJ , vol.343 , pp. d5928
    • Higgins, J.P.1    Altman, D.G.2    Gotzsche, P.C.3    Juni, P.4    Moher, D.5    Oxman, A.D.6
  • 36
    • 33845302661 scopus 로고    scopus 로고
    • Long-term effects of spironolactone on proteinuria and kidney function in patients with chronic kidney disease
    • 1:CAS:528:DC%2BD28Xht1Kju7bL 17035949
    • Bianchi S, Bigazzi R, Campese VM. Long-term effects of spironolactone on proteinuria and kidney function in patients with chronic kidney disease. Kidney Int. 2006;70:2116-23.
    • (2006) Kidney Int , vol.70 , pp. 2116-2123
    • Bianchi, S.1    Bigazzi, R.2    Campese, V.M.3
  • 37
    • 33746558934 scopus 로고    scopus 로고
    • Double-blind, placebo-controlled study on the effect of the aldosterone receptor antagonist spironolactone in patients who have persistent proteinuria and are on long-term angiotensin-converting enzyme inhibitor therapy, with or without an angiotensin II receptor blocker
    • 1:CAS:528:DC%2BD28Xjs1GrtLk%3D 17699214
    • Chrysostomou A, Pedagogos E, MacGregor L, Becker GJ. Double-blind, placebo-controlled study on the effect of the aldosterone receptor antagonist spironolactone in patients who have persistent proteinuria and are on long-term angiotensin-converting enzyme inhibitor therapy, with or without an angiotensin II receptor blocker. Clin J Am Soc Nephrol. 2006;1:256-62.
    • (2006) Clin J Am Soc Nephrol , vol.1 , pp. 256-262
    • Chrysostomou, A.1    Pedagogos, E.2    MacGregor, L.3    Becker, G.J.4
  • 38
    • 33750331264 scopus 로고    scopus 로고
    • Selective aldosterone blockade with eplerenone reduces albuminuria in patients with type 2 diabetes
    • 1:CAS:528:DC%2BD28XpvFOqsLk%3D 17699311
    • Epstein M, Williams GH, Weinberger M, Lewin A, Krause S, Mukherjee R, et al. Selective aldosterone blockade with eplerenone reduces albuminuria in patients with type 2 diabetes. Clin J Am Soc Nephrol. 2006;1:940-51.
    • (2006) Clin J Am Soc Nephrol , vol.1 , pp. 940-951
    • Epstein, M.1    Williams, G.H.2    Weinberger, M.3    Lewin, A.4    Krause, S.5    Mukherjee, R.6
  • 39
    • 24144495285 scopus 로고    scopus 로고
    • Beneficial effects of adding spironolactone to recommended antihypertensive treatment in diabetic nephropathy: A randomized, double-masked, cross-over study
    • 1:CAS:528:DC%2BD2MXhtVGntrzO 16123474
    • Rossing K, Schjoedt KJ, Smidt UM, Boomsma F, Parving HH. Beneficial effects of adding spironolactone to recommended antihypertensive treatment in diabetic nephropathy: a randomized, double-masked, cross-over study. Diabetes Care. 2005;28:2106-12.
    • (2005) Diabetes Care , vol.28 , pp. 2106-2112
    • Rossing, K.1    Schjoedt, K.J.2    Smidt, U.M.3    Boomsma, F.4    Parving, H.H.5
  • 40
    • 32844467281 scopus 로고    scopus 로고
    • Beneficial impact of spironolactone in diabetic nephropathy
    • 1:CAS:528:DC%2BD28XhslWjuw%3D%3D 16316360
    • Schjoedt KJ, Rossing K, Juhl TR, Boomsma F, Rossing P, Tarnow L, et al. Beneficial impact of spironolactone in diabetic nephropathy. Kidney Int. 2005;68:2829-36.
    • (2005) Kidney Int , vol.68 , pp. 2829-2836
    • Schjoedt, K.J.1    Rossing, K.2    Juhl, T.R.3    Boomsma, F.4    Rossing, P.5    Tarnow, L.6
  • 41
    • 49749125234 scopus 로고    scopus 로고
    • Triple pharmacological blockade of the renin-angiotensin-aldosterone system in nondiabetic CKD: An open-label crossover randomized controlled trial
    • 1:CAS:528:DC%2BD1cXhtFOrt7zO 18423812
    • Tylicki L, Rutkowski P, Renke M, Larczynski W, Aleksandrowicz E, Lysiak-Szydlowska W, et al. Triple pharmacological blockade of the renin-angiotensin-aldosterone system in nondiabetic CKD: an open-label crossover randomized controlled trial. Am J Kidney Dis. 2008;52:486-93.
    • (2008) Am J Kidney Dis , vol.52 , pp. 486-493
    • Tylicki, L.1    Rutkowski, P.2    Renke, M.3    Larczynski, W.4    Aleksandrowicz, E.5    Lysiak-Szydlowska, W.6
  • 42
    • 33750274950 scopus 로고    scopus 로고
    • Spironolactone in type 2 diabetic nephropathy: Effects on proteinuria, blood pressure and renal function
    • 17053552
    • Van Den Meiracker AH, Baggen RG, Pauli S, Lindemans A, Vulto AG, Poldermans D, et al. Spironolactone in type 2 diabetic nephropathy: Effects on proteinuria, blood pressure and renal function. J Hypertens. 2006;24:2285-92.
    • (2006) J Hypertens , vol.24 , pp. 2285-2292
    • Van Den Meiracker, A.H.1    Baggen, R.G.2    Pauli, S.3    Lindemans, A.4    Vulto, A.G.5    Poldermans, D.6
  • 43
    • 58149125532 scopus 로고    scopus 로고
    • Effects of additive therapy with spironolactone on proteinuria in diabetic patients already on ACE inhibitor or ARB therapy: Results of a randomized, placebo-controlled, double-blind, crossover trial
    • 1:CAS:528:DC%2BD1cXltl2htrw%3D 18382267
    • Saklayen MG, Gyebi LK, Tasosa J, Yap J. Effects of additive therapy with spironolactone on proteinuria in diabetic patients already on ACE inhibitor or ARB therapy: results of a randomized, placebo-controlled, double-blind, crossover trial. J Investig Med. 2008;56:714-9.
    • (2008) J Investig Med , vol.56 , pp. 714-719
    • Saklayen, M.G.1    Gyebi, L.K.2    Tasosa, J.3    Yap, J.4
  • 44
    • 42049107348 scopus 로고    scopus 로고
    • Telmisartan, ramipril or both in aptients at high risk for vascular events
    • The ONTARGET Investigators
    • The ONTARGET Investigators. Telmisartan, ramipril or both in aptients at high risk for vascular events. N Engl J Med. 2008;358:1547-59.
    • (2008) N Engl J Med , vol.358 , pp. 1547-1559
  • 45
    • 84887467090 scopus 로고    scopus 로고
    • Combined angiotensin inhibition for the treatment of diabetic nephropathy
    • 1:CAS:528:DC%2BC3sXhvVams73E 24206457
    • Fried LF, Emanuele N, Zhang JH, Brophy M, Conner TA, Duckworth W, et al. Combined angiotensin inhibition for the treatment of diabetic nephropathy. N Engl J Med. 2013;369:1892-903.
    • (2013) N Engl J Med , vol.369 , pp. 1892-1903
    • Fried, L.F.1    Emanuele, N.2    Zhang, J.H.3    Brophy, M.4    Conner, T.A.5    Duckworth, W.6
  • 46
    • 79953836889 scopus 로고    scopus 로고
    • Current strategies to achieve further cardiac and renal protection through enhanced renin-angiotensin-aldosterone system inhibition
    • 1:CAS:528:DC%2BC3MXmsVCntro%3D 21241234
    • Alfie J, Aparicio LS, Waisman GD. Current strategies to achieve further cardiac and renal protection through enhanced renin-angiotensin-aldosterone system inhibition. Rev Recent Clin Trials. 2011;6:134-46.
    • (2011) Rev Recent Clin Trials , vol.6 , pp. 134-146
    • Alfie, J.1    Aparicio, L.S.2    Waisman, G.D.3
  • 47
    • 12144252958 scopus 로고    scopus 로고
    • Aldosterone escape during blockade of the renin-angiotensin-aldosterone system in diabetic nephropathy is associated with enhanced decline in glomerular filtration rate
    • 1:CAS:528:DC%2BD2cXhtVOqs7vJ 15551047
    • Schjoedt KJ, Andersen S, Rossing P, Tarnow L, Parving HH. Aldosterone escape during blockade of the renin-angiotensin-aldosterone system in diabetic nephropathy is associated with enhanced decline in glomerular filtration rate. Diabetologia. 2004;47:1936-9.
    • (2004) Diabetologia , vol.47 , pp. 1936-1939
    • Schjoedt, K.J.1    Andersen, S.2    Rossing, P.3    Tarnow, L.4    Parving, H.H.5
  • 48
    • 83455237403 scopus 로고    scopus 로고
    • Microalbuminuria breakthrough under chronic renin-angiotensin-aldosterone system suppression
    • 1:CAS:528:DC%2BC3MXhs1WksrfJ 22080225
    • Cerezo C, Ruilope LM, Segura J, Garcia-Donaire JA, de la Cruz JJ, Banegas JR, et al. Microalbuminuria breakthrough under chronic renin-angiotensin-aldosterone system suppression. J Hypertens. 2012;30:204-9.
    • (2012) J Hypertens , vol.30 , pp. 204-209
    • Cerezo, C.1    Ruilope, L.M.2    Segura, J.3    Garcia-Donaire, J.A.4    De La Cruz, J.J.5    Banegas, J.R.6
  • 49
    • 31544448314 scopus 로고    scopus 로고
    • Regression of existing glomerulosclerosis by inhibition of aldosterone
    • 1:CAS:528:DC%2BD2MXht1Cnsr3M 16192423
    • Aldigier JC, Kanjanbuch T, Ma LJ, Brown NJ, Fogo AB. Regression of existing glomerulosclerosis by inhibition of aldosterone. J Am Soc Nephrol. 2005;16:3306-14.
    • (2005) J Am Soc Nephrol , vol.16 , pp. 3306-3314
    • Aldigier, J.C.1    Kanjanbuch, T.2    Ma, L.J.3    Brown, N.J.4    Fogo, A.B.5
  • 50
    • 84938947090 scopus 로고    scopus 로고
    • Drug-Induced Reduction in Albuminuria Is Associated with Subsequent Renoprotection: A Meta-Analysis
    • Lambers-Heerspink HJ, et al. Drug-Induced Reduction in Albuminuria Is Associated with Subsequent Renoprotection: A Meta-Analysis. J Am Soc Nephrol. 2015;26(8):2055-64.
    • (2015) J Am Soc Nephrol. , vol.26 , Issue.8 , pp. 2055-2064
    • Lambers-Heerspink, H.J.1
  • 51
    • 4344621497 scopus 로고    scopus 로고
    • Albuminuria, a therapeutic target for cardiovascular protection in type 2 diabetic patients with nephropathy
    • de ZD, Remuzzi G, Parving HH, Keane WF, Zhang Z, Shahinfar S, et al. Albuminuria, a therapeutic target for cardiovascular protection in type 2 diabetic patients with nephropathy. Circulation. 2004;110:921-7.
    • (2004) Circulation , vol.110 , pp. 921-927
    • De, Z.D.1    Remuzzi, G.2    Parving, H.H.3    Keane, W.F.4    Zhang, Z.5    Shahinfar, S.6
  • 52
    • 84900310067 scopus 로고    scopus 로고
    • Benefits of Aldosterone Receptor Antagonism in Chronic Kidney Disease (BARACK D) trial-a multi-centre, prospective, randomised, open, blinded end-point
    • 24886488 4113231 36-month study of 2,616 patients within primary care with stage 3b chronic kidney disease to compare the efficacy of spironolactone 25 mg once daily in addition to routine care on mortality and cardiovascular outcomes versus routine care alone: Study protocol for a randomized controlled trial
    • Hill NR, Lasserson D, Thompson B, Perera-Salazar R, Wolstenholme J, Bower P, et al. Benefits of Aldosterone Receptor Antagonism in Chronic Kidney Disease (BARACK D) trial-a multi-centre, prospective, randomised, open, blinded end-point, 36-month study of 2,616 patients within primary care with stage 3b chronic kidney disease to compare the efficacy of spironolactone 25 mg once daily in addition to routine care on mortality and cardiovascular outcomes versus routine care alone: study protocol for a randomized controlled trial. Trials. 2014;15:160.
    • (2014) Trials , vol.15 , pp. 160
    • Hill, N.R.1    Lasserson, D.2    Thompson, B.3    Perera-Salazar, R.4    Wolstenholme, J.5    Bower, P.6
  • 53
    • 77953291706 scopus 로고    scopus 로고
    • Association of estimated glomerular filtration rate and albuminuria with all-cause and cardiovascular mortality in general population cohorts: A collaborative meta-analysis
    • 20483451 3993088
    • Matsushita K, van d V, Astor BC, Woodward M, Levey AS, de Jong PE, et al. Association of estimated glomerular filtration rate and albuminuria with all-cause and cardiovascular mortality in general population cohorts: a collaborative meta-analysis. Lancet. 2010;375:2073-81.
    • (2010) Lancet , vol.375 , pp. 2073-2081
    • Matsushita, K.1    Van d, V.2    Astor, B.C.3    Woodward, M.4    Levey, A.S.5    De Jong, P.E.6
  • 54
    • 79953787215 scopus 로고    scopus 로고
    • Increased serum potassium affects renal outcomes: A post hoc analysis of the Reduction of Endpoints in NIDDM with the Angiotensin II Antagonist Losartan (RENAAL) trial
    • 1:CAS:528:DC%2BC3cXhsFWqtLvF 20882268
    • Miao Y, Dobre D, Heerspink HJ, Brenner BM, Cooper ME, Parving HH, et al. Increased serum potassium affects renal outcomes: a post hoc analysis of the Reduction of Endpoints in NIDDM with the Angiotensin II Antagonist Losartan (RENAAL) trial. Diabetologia. 2011;54:44-50.
    • (2011) Diabetologia , vol.54 , pp. 44-50
    • Miao, Y.1    Dobre, D.2    Heerspink, H.J.3    Brenner, B.M.4    Cooper, M.E.5    Parving, H.H.6
  • 55
    • 84940729269 scopus 로고    scopus 로고
    • Effect of finerenone on albuminuria in patients with diabetic nephropathy: A randomized clinical trial
    • 1:CAS:528:DC%2BC28XkslKntQ%3D%3D 26325557
    • Bakris GL, Agarwal R, Chan JC, Cooper ME, Gansevoort RT, Haller H, et al. Effect of finerenone on albuminuria in patients with diabetic nephropathy: a randomized clinical trial. JAMA. 2015;314:884-94.
    • (2015) JAMA , vol.314 , pp. 884-894
    • Bakris, G.L.1    Agarwal, R.2    Chan, J.C.3    Cooper, M.E.4    Gansevoort, R.T.5    Haller, H.6
  • 56
    • 84920982556 scopus 로고    scopus 로고
    • Patiromer in patients with kidney disease and hyperkalemia receiving RAAS inhibitors
    • 25415805
    • Weir MR, Bakris GL, Bushinsky DA, Mayo MR, Garza D, Stasiv Y, et al. Patiromer in patients with kidney disease and hyperkalemia receiving RAAS inhibitors. N Engl J Med. 2015;372:211-21.
    • (2015) N Engl J Med , vol.372 , pp. 211-221
    • Weir, M.R.1    Bakris, G.L.2    Bushinsky, D.A.3    Mayo, M.R.4    Garza, D.5    Stasiv, Y.6


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