Pretreatment with mineralocorticoid receptor blocker reduces intestinal injury induced by ischemia and reperfusion: Involvement of inhibition of inflammatory response, oxidative stress, nuclear factor κb, and inducible nitric oxide synthase

Journal of Surgical Research

Volumn 191, Issue 2, 2014, Pages 350-361

  Ozacmak, Hale Sayan ^a   Ozacmak, Veysel Haktan ^a   Barut, Figen ^a   Arasli, Mehmet ^a   Ucan, Bulent Hamdi ^a  

^a ZONGULDAK KARAELMAS UNIVERSITY   (Turkey)

Author keywords

Caspase 3; Cytokines; iNOS; Intestinal ischemia reperfusion; Mineralocorticoid receptor blocker; NF B; Spironolactone

Indexed keywords

CASPASE 3; GAMMA INTERFERON; GLUTATHIONE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1ALPHA; INTERLEUKIN 4; MALONALDEHYDE; MINERALOCORTICOID RECEPTOR; MONOCYTE CHEMOTACTIC PROTEIN 1; MYELOPEROXIDASE; SPIRONOLACTONE; TUMOR NECROSIS FACTOR ALPHA; CYTOKINE; MINERALOCORTICOID ANTAGONIST; NOS2 PROTEIN, RAT;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVITY; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; INTESTINE INJURY; MALE; NONHUMAN; OXIDATIVE STRESS; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; RAT; REPERFUSION INJURY; ANIMAL; BLOOD; INFLAMMATION; INOS; INTESTINAL ISCHEMIA REPERFUSION; METABOLISM; MINERALOCORTICOID RECEPTOR BLOCKER; NEUTROPHIL CHEMOTAXIS; NF-ΚB; PHYSIOLOGY; WISTAR RAT;

CASPASE-3; CYTOKINES; INOS; INTESTINAL ISCHEMIA REPERFUSION; MINERALOCORTICOID RECEPTOR BLOCKER; NF-ΚB; SPIRONOLACTONE;

ANIMALS; GLUTATHIONE; INFLAMMATION; MALE; MINERALOCORTICOID RECEPTOR ANTAGONISTS; NEUTROPHIL INFILTRATION; NF-KAPPA B; NITRIC OXIDE SYNTHASE TYPE II; OXIDATIVE STRESS; RATS; RATS, WISTAR; REPERFUSION INJURY; SPIRONOLACTONE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84908246474     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2014.04.040     Document Type: Article

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