-
1
-
-
0033517302
-
The effect of spironolactone on morbidity and mortality in patients with severe heart failure
-
Pitt B, Zannad F, Remme WJ, et al. The effect of spironolactone on morbidity and mortality in patients with severe heart failure. N Engl J Med. 1999;341:709-717.
-
(1999)
N Engl J Med
, vol.341
, pp. 709-717
-
-
Pitt, B.1
Zannad, F.2
Remme, W.J.3
-
2
-
-
35848931662
-
Long-term cardiac effects of adrenalectomy or mineralocorticoid antagonists in patients with primary aldosteronism
-
Catena C, Colussi G, Lapenna R, et al. Long-term cardiac effects of adrenalectomy or mineralocorticoid antagonists in patients with primary aldosteronism. Hypertension. 2007;50:911-918.
-
(2007)
Hypertension
, vol.50
, pp. 911-918
-
-
Catena, C.1
Colussi, G.2
Lapenna, R.3
-
3
-
-
0036841807
-
Aldosteroneinduced inflammation in the rat heart: Role of oxidative stress
-
Sun Y, Zhang J, Lu L, Chen SS, Quinn MT, Weber KT. Aldosteroneinduced inflammation in the rat heart: role of oxidative stress. Am J Pathol. 2002;161:1773-1781.
-
(2002)
Am J Pathol
, vol.161
, pp. 1773-1781
-
-
Sun, Y.1
Zhang, J.2
Lu, L.3
Chen, S.S.4
Quinn, M.T.5
Weber, K.T.6
-
4
-
-
0037373553
-
Early inflammatory responses in experimental cardiac hypertrophy and fibrosis: Effects of 11 ô-hydroxysteroid dehydrogenase inactivation
-
Young MJ, Moussa L, Dilley R, Funder JW. Early inflammatory responses in experimental cardiac hypertrophy and fibrosis: effects of 11 ô-hydroxysteroid dehydrogenase inactivation. Endocrinology. 2003;144:1121-1125.
-
(2003)
Endocrinology
, vol.144
, pp. 1121-1125
-
-
Young, M.J.1
Moussa, L.2
Dilley, R.3
Funder, J.W.4
-
5
-
-
84896824490
-
CCL2-dependent macrophage recruitment is critical for mineralocorticoid receptor-mediated cardiac fibrosis, inflammation, and blood pressure responses in male mice
-
Shen JZ, Morgan J, Tesch GH, Fuller PJ, Young MJ. CCL2-dependent macrophage recruitment is critical for mineralocorticoid receptor-mediated cardiac fibrosis, inflammation, and blood pressure responses in male mice. Endocrinology. 2014;155:1057-1066.
-
(2014)
Endocrinology
, vol.155
, pp. 1057-1066
-
-
Shen, J.Z.1
Morgan, J.2
Tesch, G.H.3
Fuller, P.J.4
Young, M.J.5
-
6
-
-
70349257487
-
Deletion of mineralocorticoid receptors from macrophages protects against deoxycorticosterone/salt-induced cardiac fibrosis and increased blood pressure
-
Rickard AJ, Morgan J, Tesch G, Funder JW, Fuller PJ, Young MJ. Deletion of mineralocorticoid receptors from macrophages protects against deoxycorticosterone/salt-induced cardiac fibrosis and increased blood pressure. Hypertension. 2009;54:537-543.
-
(2009)
Hypertension
, vol.54
, pp. 537-543
-
-
Rickard, A.J.1
Morgan, J.2
Tesch, G.3
Funder, J.W.4
Fuller, P.J.5
Young, M.J.6
-
7
-
-
77956388193
-
Myeloid mineralocorticoid receptor controls macrophage polarization and cardiovascular hypertrophy and remodeling in mice
-
Usher MG, Duan SZ, Ivaschenko CY, et al. Myeloid mineralocorticoid receptor controls macrophage polarization and cardiovascular hypertrophy and remodeling in mice. J Clin Invest. 2010;120: 3350-3364.
-
(2010)
J Clin Invest
, vol.120
, pp. 3350-3364
-
-
Usher, M.G.1
Duan, S.Z.2
Ivaschenko, C.Y.3
-
8
-
-
84897086339
-
Spironolactone decreases DOCA-salt-induced organ damage by blocking the activation of T helper 17 and the downregulation of regulatory T lymphocytes
-
Amador CA, Barrientos V, Pena J, et al. Spironolactone decreases DOCA-salt-induced organ damage by blocking the activation of T helper 17 and the downregulation of regulatory T lymphocytes. Hypertension. 2014;63:797-803.
-
(2014)
Hypertension
, vol.63
, pp. 797-803
-
-
Amador, C.A.1
Barrientos, V.2
Pena, J.3
-
9
-
-
84929688304
-
Mineralocorticoid receptor blockade prevents Western diet-induced diastolic dysfunction in female mice
-
Bostick B, Habibi J, DeMarco VG, et al. Mineralocorticoid receptor blockade prevents Western diet-induced diastolic dysfunction in female mice. Am J Physiol Heart Circ Physiol. 2015;308:H1126-H1135.
-
(2015)
Am J Physiol Heart Circ Physiol
, vol.308
, pp. H1126-H1135
-
-
Bostick, B.1
Habibi, J.2
DeMarco, V.G.3
-
10
-
-
73949146218
-
Aldosterone promotes autoimmune damage by enhancing Th17-mediated immunity
-
Herrada AA, Contreras FJ, Marini NP, et al. Aldosterone promotes autoimmune damage by enhancing Th17-mediated immunity. J Immunol. 2010;184:191-202.
-
(2010)
J Immunol
, vol.184
, pp. 191-202
-
-
Herrada, A.A.1
Contreras, F.J.2
Marini, N.P.3
-
11
-
-
38549136572
-
Macrophage activation by endogenous danger signals
-
Zhang X, Mosser DM. Macrophage activation by endogenous danger signals. J Pathol. 2008;214:161-178.
-
(2008)
J Pathol
, vol.214
, pp. 161-178
-
-
Zhang, X.1
Mosser, D.M.2
-
12
-
-
77956976681
-
Macrophage plasticity and interaction with lymphocyte subsets: Cancer as a paradigm
-
Biswas SK, Mantovani A. Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm. Nat Immunol. 2010;11:889-896.
-
(2010)
Nat Immunol
, vol.11
, pp. 889-896
-
-
Biswas, S.K.1
Mantovani, A.2
-
13
-
-
84860997131
-
An abundant tissue macrophage population in the adult murine heart with a distinct alternatively-activated macrophage profile
-
Pinto AR, Paolicelli R, Salimova E, et al. An abundant tissue macrophage population in the adult murine heart with a distinct alternatively-activated macrophage profile. PLoS One. 2012;7: e36814.
-
(2012)
PLoS One
, vol.7
, pp. e36814
-
-
Pinto, A.R.1
Paolicelli, R.2
Salimova, E.3
-
14
-
-
84860439438
-
Reciprocal interaction between macrophages and T cells stimulates IFN-γ and MCP-1 production in Ang II-induced cardiac inflammation and fibrosis
-
Han YL, Li YL, Jia LX, et al. Reciprocal interaction between macrophages and T cells stimulates IFN-γ and MCP-1 production in Ang II-induced cardiac inflammation and fibrosis. PLoS One. 2012; 7:e35506.
-
(2012)
PLoS One
, vol.7
, pp. e35506
-
-
Han, Y.L.1
Li, Y.L.2
Jia, L.X.3
-
15
-
-
0033177995
-
Conditional gene targeting in macrophages and granulocytes using LysMcre mice
-
Clausen BE, Burkhardt C, Reith W, Renkawitz R, Forster I. Conditional gene targeting in macrophages and granulocytes using LysMcre mice. Transgenic Res. 1999;8:265-277.
-
(1999)
Transgenic Res
, vol.8
, pp. 265-277
-
-
Clausen, B.E.1
Burkhardt, C.2
Reith, W.3
Renkawitz, R.4
Forster, I.5
-
16
-
-
84870250634
-
Cardiomyocyte mineralocorticoid receptors are essential for deoxycorticosterone/salt-mediated inflammation and cardiac fibrosis
-
Rickard AJ, Morgan J, Bienvenu LA, et al. Cardiomyocyte mineralocorticoid receptors are essential for deoxycorticosterone/salt-mediated inflammation and cardiac fibrosis. Hypertension. 2012;60: 1443-1450.
-
(2012)
Hypertension
, vol.60
, pp. 1443-1450
-
-
Rickard, A.J.1
Morgan, J.2
Bienvenu, L.A.3
-
17
-
-
12144285372
-
Is aldosterone synthesized within the rat brain?
-
Gomez-Sanchez EP, Ahmad N, Romero DG, Gomez-Sanchez CE. Is aldosterone synthesized within the rat brain? Am J Physiol Endocrinol Metab. 2005;288(2):E342-E346.
-
(2005)
Am J Physiol Endocrinol Metab
, vol.288
, Issue.2
, pp. E342-E346
-
-
Gomez-Sanchez, E.P.1
Ahmad, N.2
Romero, D.G.3
Gomez-Sanchez, C.E.4
-
18
-
-
84862737919
-
Macrophage mineralocorticoid receptor signaling plays a key role in aldosterone-independent cardiac fibrosis
-
Bienvenu LA, Morgan J, Rickard AJ, et al. Macrophage mineralocorticoid receptor signaling plays a key role in aldosterone-independent cardiac fibrosis. Endocrinology. 2012;153:3416-3425.
-
(2012)
Endocrinology
, vol.153
, pp. 3416-3425
-
-
Bienvenu, L.A.1
Morgan, J.2
Rickard, A.J.3
-
19
-
-
0029911694
-
Metalloelastase is required for macrophage-mediated proteolysis and matrix invasion in mice
-
Shipley JM, Wesselschmidt RL, Kobayashi DK, Ley TJ, Shapiro SD. Metalloelastase is required for macrophage-mediated proteolysis and matrix invasion in mice. Proc Natl Acad Sci USA. 1996;93: 3942-3946.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 3942-3946
-
-
Shipley, J.M.1
Wesselschmidt, R.L.2
Kobayashi, D.K.3
Ley, T.J.4
Shapiro, S.D.5
-
20
-
-
34147099468
-
Transforming growth factor (TGF)-β1 stimulates pulmonary fibrosis and inflammation via a Bax-dependent, Bid-activated pathway that involves matrix metalloproteinase-12
-
Kang H-R, Cho SJ, Lee CG, Homer RJ, Elias JA. Transforming growth factor (TGF)-β1 stimulates pulmonary fibrosis and inflammation via a Bax-dependent, Bid-activated pathway that involves matrix metalloproteinase-12. J Biol Chem. 2007;282: 7723-7732.
-
(2007)
J Biol Chem
, vol.282
, pp. 7723-7732
-
-
Kang, H.-R.1
Cho, S.J.2
Lee, C.G.3
Homer, R.J.4
Elias, J.A.5
-
21
-
-
77951627980
-
Matrix metalloproteinase 12-deficiency augments extracellular matrix degrading metalloproteinases and attenuates IL-13-dependent fibrosis
-
Madala SK, Pesce JT, Ramalingam TR, et al. Matrix metalloproteinase 12-deficiency augments extracellular matrix degrading metalloproteinases and attenuates IL-13-dependent fibrosis. J Immunol. 2010;184:3955-3963.
-
(2010)
J Immunol
, vol.184
, pp. 3955-3963
-
-
Madala, S.K.1
Pesce, J.T.2
Ramalingam, T.R.3
-
22
-
-
84864535402
-
Classical macrophage activation up-regulates several matrix metalloproteinases through mitogen activated protein kinases and nuclear factor-ΚB
-
Huang W-C, Sala-Newby GB, Susana A, Johnson JL, Newby AC. Classical macrophage activation up-regulates several matrix metalloproteinases through mitogen activated protein kinases and nuclear factor-ΚB. PLoS One. 2012;7:e42507.
-
(2012)
PLoS One
, vol.7
, pp. e42507
-
-
Huang, W.-C.1
Sala-Newby, G.B.2
Susana, A.3
Johnson, J.L.4
Newby, A.C.5
-
23
-
-
0034682848
-
Transforming growth factor-β1 inhibits cytokine-mediated induction of human metalloelastase in macrophages
-
Feinberg MW, Jain MK, Werner F, et al. Transforming growth factor-β1 inhibits cytokine-mediated induction of human metalloelastase in macrophages. J Biol Chem. 2000;275:25766-25773.
-
(2000)
J Biol Chem
, vol.275
, pp. 25766-25773
-
-
Feinberg, M.W.1
Jain, M.K.2
Werner, F.3
-
24
-
-
84907841720
-
MMP-12 deficiency attenuates angiotensin II-induced vascular injury, M2 macrophage accumulation, and skin and heart fibrosis
-
Stawski L, Haines P, Fine A, Rudnicka L, Trojanowska M. MMP-12 deficiency attenuates angiotensin II-induced vascular injury, M2 macrophage accumulation, and skin and heart fibrosis. PLoS One. 2014;9:e109763.
-
(2014)
PLoS One
, vol.9
, pp. e109763
-
-
Stawski, L.1
Haines, P.2
Fine, A.3
Rudnicka, L.4
Trojanowska, M.5
-
25
-
-
63449084230
-
Blockade of the c-Jun amino terminal kinase prevents crescent formation and halts established anti-GBM glomerulonephritis in the rat
-
Ma FY, Flanc RS, Tesch GH, Bennett BL, Friedman GC, Nikolic-Paterson DJ. Blockade of the c-Jun amino terminal kinase prevents crescent formation and halts established anti-GBM glomerulonephritis in the rat. Lab Invest. 2009;89:470-484.
-
(2009)
Lab Invest
, vol.89
, pp. 470-484
-
-
Ma, F.Y.1
Flanc, R.S.2
Tesch, G.H.3
Bennett, B.L.4
Friedman, G.C.5
Nikolic-Paterson, D.J.6
-
26
-
-
84948674383
-
ERK signaling is essential for macrophage development
-
Richardson ET, Shukla S, Nagy N, et al. ERK signaling is essential for macrophage development. PLoS One. 2015;10:e0140064.
-
(2015)
PLoS One
, vol.10
, pp. e0140064
-
-
Richardson, E.T.1
Shukla, S.2
Nagy, N.3
-
27
-
-
84872142459
-
JNK expression by macrophages promotes obesity-induced insulin resistance and inflammation
-
Han MS, Jung DY, Morel C, et al. JNK expression by macrophages promotes obesity-induced insulin resistance and inflammation. Science. 2013;339:218-222.
-
(2013)
Science
, vol.339
, pp. 218-222
-
-
Han, M.S.1
Jung, D.Y.2
Morel, C.3
-
28
-
-
84869861374
-
Aldosterone induces kidney fibroblast proliferation via activation of growth factor receptors and PI3K/MAPK signalling
-
Huang LL, Nikolic-Paterson DJ, Ma FY, Tesch GH. Aldosterone induces kidney fibroblast proliferation via activation of growth factor receptors and PI3K/MAPK signalling. Nephron Exp Nephrol. 2012;120:e115- e122.
-
(2012)
Nephron Exp Nephrol
, vol.120
, pp. e115-e122
-
-
Huang, L.L.1
Nikolic-Paterson, D.J.2
Ma, F.Y.3
Tesch, G.H.4
-
29
-
-
20044387192
-
Macrophage galactose-type C-type lectins as novel markers for alternatively activated macrophages elicited by parasitic infections and allergic airway inflammation
-
Raes G, Brys L, Dahal BK, et al. Macrophage galactose-type C-type lectins as novel markers for alternatively activated macrophages elicited by parasitic infections and allergic airway inflammation. J Leukoc Biol. 2005;77:321-327.
-
(2005)
J Leukoc Biol
, vol.77
, pp. 321-327
-
-
Raes, G.1
Brys, L.2
Dahal, B.K.3
-
30
-
-
0032526864
-
Interferon-inducible T cell α chemoattractant (I-TAC): A novel non-ELR CXC chemokine with potent activity on activated T cells through selective high affinity binding to CXCR3
-
Cole KE, Strick CA, Paradis TJ, et al. Interferon-inducible T cell α chemoattractant (I-TAC): a novel non-ELR CXC chemokine with potent activity on activated T cells through selective high affinity binding to CXCR3. J Exp Med. 1998;187:2009-2021.
-
(1998)
J Exp Med
, vol.187
, pp. 2009-2021
-
-
Cole, K.E.1
Strick, C.A.2
Paradis, T.J.3
-
31
-
-
79952091851
-
CXCR3 in T cell function
-
Groom JR, Luster AD. CXCR3 in T cell function. Exp Cell Res. 2011;317:620-631.
-
(2011)
Exp Cell Res
, vol.317
, pp. 620-631
-
-
Groom, J.R.1
Luster, A.D.2
-
32
-
-
34948825774
-
Role of the T cell in the genesis of angiotensin II-induced hypertension and vascular dysfunction
-
Guzik TJ, Hoch NE, Brown KA, et al. Role of the T cell in the genesis of angiotensin II-induced hypertension and vascular dysfunction. J Exp Med. 2007;204:2449-2460.
-
(2007)
J Exp Med
, vol.204
, pp. 2449-2460
-
-
Guzik, T.J.1
Hoch, N.E.2
Brown, K.A.3
-
33
-
-
74949108521
-
Interleukin 17 promotes angiotensin II-induced hypertension and vascular dysfunction
-
Madhur MS, Lob HE, McCann LA, et al. Interleukin 17 promotes angiotensin II-induced hypertension and vascular dysfunction. Hypertension. 2010;55:500-507.
-
(2010)
Hypertension
, vol.55
, pp. 500-507
-
-
Madhur, M.S.1
Lob, H.E.2
McCann, L.A.3
-
34
-
-
79955565441
-
Fibrosis is regulated by Th2 and Th17 responses and by dynamic interactions between fibroblasts and macrophages
-
Barron L, Wynn TA. Fibrosis is regulated by Th2 and Th17 responses and by dynamic interactions between fibroblasts and macrophages. Am J Physiol Gastrointest Liver Physiol. 2011;300: G723-G728.
-
(2011)
Am J Physiol Gastrointest Liver Physiol
, vol.300
, pp. G723-G728
-
-
Barron, L.1
Wynn, T.A.2
-
35
-
-
32644432669
-
Direct effects of aldosterone on cardiomyocytes in the presence of normal and elevated extracellular sodium
-
Yamamuro M, Yoshimura M, Nakayama M, et al. Direct effects of aldosterone on cardiomyocytes in the presence of normal and elevated extracellular sodium. Endocrinology. 2006;147:1314-1321.
-
(2006)
Endocrinology
, vol.147
, pp. 1314-1321
-
-
Yamamuro, M.1
Yoshimura, M.2
Nakayama, M.3
-
36
-
-
84880730419
-
Long-term control of arterial hypertension and regression of left ventricular hypertrophy with treatment of primary aldosteronism
-
Rossi GP, Cesari M, Cuspidi C, et al. Long-term control of arterial hypertension and regression of left ventricular hypertrophy with treatment of primary aldosteronism. Hypertension. 2013; 62:62-69.
-
(2013)
Hypertension
, vol.62
, pp. 62-69
-
-
Rossi, G.P.1
Cesari, M.2
Cuspidi, C.3
|