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Volumn 293, Issue 1, 2007, Pages

Renal ischemia-reperfusion injury is prevented by the mineralocorticoid receptor blocker spironolactone

Author keywords

Apoptosis; Endothelial nitric oxide synthase; Lipoperoxidation

Indexed keywords

MINERALOCORTICOID RECEPTOR; SPIRONOLACTONE; ALDOSTERONE; ALDOSTERONE ANTAGONIST; CATALASE; GLUTATHIONE PEROXIDASE; MALONALDEHYDE; RNA; SUPEROXIDE DISMUTASE;

EID: 34548012161     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00077.2007     Document Type: Article
Times cited : (122)

References (51)
  • 3
    • 18844387606 scopus 로고    scopus 로고
    • Aldosterone and end-organ damage
    • Brown NJ. Aldosterone and end-organ damage. Curr Opin Nephrol Hypertens 14: 235-241, 2005.
    • (2005) Curr Opin Nephrol Hypertens , vol.14 , pp. 235-241
    • Brown, N.J.1
  • 4
    • 33746558934 scopus 로고    scopus 로고
    • Double-blind, placebo-controlled study on the effect of the aldosterone receptor antagonist spironolactone in patients who have persistent proteinuria and are on long-term angiotensin-converting enzyme inhibitor therapy, with or without an angiotensin II receptor blocker
    • Chrysostomou A, Pedagogos E, MacGregor L, Becker GJ. Double-blind, placebo-controlled study on the effect of the aldosterone receptor antagonist spironolactone in patients who have persistent proteinuria and are on long-term angiotensin-converting enzyme inhibitor therapy, with or without an angiotensin II receptor blocker. Clin J Am Soc Nephrol 1: 256-262, 2006.
    • (2006) Clin J Am Soc Nephrol , vol.1 , pp. 256-262
    • Chrysostomou, A.1    Pedagogos, E.2    MacGregor, L.3    Becker, G.J.4
  • 5
    • 0035922443 scopus 로고    scopus 로고
    • Spironolactone in addition to ACE inhibition to reduce proteinuria in patients with chronic renal disease
    • Chrysostomou A, Becker G. Spironolactone in addition to ACE inhibition to reduce proteinuria in patients with chronic renal disease. N Engl J Med 345: 925-926, 2001.
    • (2001) N Engl J Med , vol.345 , pp. 925-926
    • Chrysostomou, A.1    Becker, G.2
  • 7
    • 0023370667 scopus 로고
    • Cyclosporine-induced acute renal dysfunction in the rat. Evidence of arteriolar vasoconstriction with preservation of tubular function
    • English J, Evan A, Houghton DC, Bennett WM. Cyclosporine-induced acute renal dysfunction in the rat. Evidence of arteriolar vasoconstriction with preservation of tubular function. Transplantation 44: 135-141, 1987.
    • (1987) Transplantation , vol.44 , pp. 135-141
    • English, J.1    Evan, A.2    Houghton, D.C.3    Bennett, W.M.4
  • 10
    • 3242806045 scopus 로고    scopus 로고
    • Inflammatory cells in ischemic acute renal failure
    • Friedewald JJ, Rabb H. Inflammatory cells in ischemic acute renal failure. Kidney Int 66: 486-491, 2004.
    • (2004) Kidney Int , vol.66 , pp. 486-491
    • Friedewald, J.J.1    Rabb, H.2
  • 11
    • 3142634795 scopus 로고    scopus 로고
    • NO bioavailability, endothelial dysfunction, and acute renal failure: New insights into pathophysiology
    • Goligorsky MS, Brodsky SV, Noiri E. NO bioavailability, endothelial dysfunction, and acute renal failure: new insights into pathophysiology. Semin Nephrol 24: 316-323, 2004.
    • (2004) Semin Nephrol , vol.24 , pp. 316-323
    • Goligorsky, M.S.1    Brodsky, S.V.2    Noiri, E.3
  • 14
    • 77049290688 scopus 로고
    • Turbidimetric determination of proteins with sulfosalicylic and trichloroacetic acid
    • Henry RJ, Sobel C, Segalove M. Turbidimetric determination of proteins with sulfosalicylic and trichloroacetic acid. Proc Soc Exp Biol Med 92: 748-751, 1956.
    • (1956) Proc Soc Exp Biol Med , vol.92 , pp. 748-751
    • Henry, R.J.1    Sobel, C.2    Segalove, M.3
  • 15
    • 3042845741 scopus 로고    scopus 로고
    • Aldosterone in the development and progression of renal injury
    • Hollenberg NK. Aldosterone in the development and progression of renal injury. Kidney Int 66: 1-9, 2004.
    • (2004) Kidney Int , vol.66 , pp. 1-9
    • Hollenberg, N.K.1
  • 16
    • 0042320418 scopus 로고    scopus 로고
    • Aldosterone in chronic kidney and cardiac disease
    • Hostetter TH, Ibrahim HN. Aldosterone in chronic kidney and cardiac disease. J Am Soc Nephrol 14: 2395-2401, 2003.
    • (2003) J Am Soc Nephrol , vol.14 , pp. 2395-2401
    • Hostetter, T.H.1    Ibrahim, H.N.2
  • 17
    • 3242793421 scopus 로고    scopus 로고
    • The role of mitochondria in ischemia/reperfusion injury in organ transplantation
    • Jassem W, Heaton ND. The role of mitochondria in ischemia/reperfusion injury in organ transplantation. Kidney Int 66: 514-517, 2004.
    • (2004) Kidney Int , vol.66 , pp. 514-517
    • Jassem, W.1    Heaton, N.D.2
  • 18
    • 0034879042 scopus 로고    scopus 로고
    • alpha-MSH decreases apoptosis in ischaemic acute renal failure in rats: Possible mechanism of this beneficial effect
    • Jo SK, Yun SY, Chang KH, Cha DR, Cho WY, Kim HK, Won NH. alpha-MSH decreases apoptosis in ischaemic acute renal failure in rats: possible mechanism of this beneficial effect. Nephrol Dial Transplant 16: 1583-1591, 2001.
    • (2001) Nephrol Dial Transplant , vol.16 , pp. 1583-1591
    • Jo, S.K.1    Yun, S.Y.2    Chang, K.H.3    Cha, D.R.4    Cho, W.Y.5    Kim, H.K.6    Won, N.H.7
  • 19
    • 21244458789 scopus 로고    scopus 로고
    • Effect of aldosterone and mineralocorticoid receptor blockade on vascular inflammation
    • Joffe HV, Adler GK. Effect of aldosterone and mineralocorticoid receptor blockade on vascular inflammation. Heart Fail Rev 10: 31-37, 2005.
    • (2005) Heart Fail Rev , vol.10 , pp. 31-37
    • Joffe, H.V.1    Adler, G.K.2
  • 20
    • 3242744482 scopus 로고    scopus 로고
    • Apoptotic pathways in ischemic acute renal failure
    • Kaushal GP, Basnakian AG, Shah SV. Apoptotic pathways in ischemic acute renal failure. Kidney Int 66: 500-506, 2004.
    • (2004) Kidney Int , vol.66 , pp. 500-506
    • Kaushal, G.P.1    Basnakian, A.G.2    Shah, S.V.3
  • 21
    • 33644834056 scopus 로고    scopus 로고
    • Acute renal failure: Much more than a kidney disease
    • Kelly KJ. Acute renal failure: much more than a kidney disease. Semin Nephrol 26: 105-113, 2006.
    • (2006) Semin Nephrol , vol.26 , pp. 105-113
    • Kelly, K.J.1
  • 22
    • 0033977753 scopus 로고    scopus 로고
    • Acute renal failure in the new millennium: Time to consider combination therapy
    • Kelly KJ, Molitoris BA. Acute renal failure in the new millennium: time to consider combination therapy. Semin Nephrol 20: 4-19, 2000.
    • (2000) Semin Nephrol , vol.20 , pp. 4-19
    • Kelly, K.J.1    Molitoris, B.A.2
  • 25
    • 0023154140 scopus 로고
    • The influence of enalapril or spironolactone on experimental cyclosporin nephrotoxicity
    • McAuley FT, Whiting PH, Thomson AW, Simpson JG. The influence of enalapril or spironolactone on experimental cyclosporin nephrotoxicity. Biochem Pharmacol 36: 699-703, 1987.
    • (1987) Biochem Pharmacol , vol.36 , pp. 699-703
    • McAuley, F.T.1    Whiting, P.H.2    Thomson, A.W.3    Simpson, J.G.4
  • 27
    • 3242776230 scopus 로고    scopus 로고
    • Endothelial injury and dysfunction: Role in the extension phase of acute renal failure
    • Molitoris BA, Sutton TA. Endothelial injury and dysfunction: role in the extension phase of acute renal failure. Kidney Int 66: 496-499, 2004.
    • (2004) Kidney Int , vol.66 , pp. 496-499
    • Molitoris, B.A.1    Sutton, T.A.2
  • 30
    • 31544466805 scopus 로고    scopus 로고
    • Molecular mechanisms and therapeutic strategies of chronic renal injury: Renoprotective effects of aldosterone blockade
    • Nishiyama A, Abe Y. Molecular mechanisms and therapeutic strategies of chronic renal injury: renoprotective effects of aldosterone blockade. J Pharmacol Sci 100: 9-16, 2006.
    • (2006) J Pharmacol Sci , vol.100 , pp. 9-16
    • Nishiyama, A.1    Abe, Y.2
  • 34
    • 0033517302 scopus 로고    scopus 로고
    • The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study Investigators
    • Pitt B, Zannad F, Remme WJ, Cody R, Castaigne A, Perez A, Palensky J, Wittes J. The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study Investigators. N Engl J Med 341: 709-717, 1999.
    • (1999) N Engl J Med , vol.341 , pp. 709-717
    • Pitt, B.1    Zannad, F.2    Remme, W.J.3    Cody, R.4    Castaigne, A.5    Perez, A.6    Palensky, J.7    Wittes, J.8
  • 35
    • 0032588244 scopus 로고    scopus 로고
    • Angiotensin AT1 receptor subtype as a cardiac target of aldosterone: Role in aldosterone-salt-induced fibrosis
    • Robert V, Heymes C, Silvestre JS, Sabri A, Swynghedauw B, Delcayre C. Angiotensin AT1 receptor subtype as a cardiac target of aldosterone: role in aldosterone-salt-induced fibrosis. Hypertension 33: 981-986, 1999.
    • (1999) Hypertension , vol.33 , pp. 981-986
    • Robert, V.1    Heymes, C.2    Silvestre, J.S.3    Sabri, A.4    Swynghedauw, B.5    Delcayre, C.6
  • 36
    • 0031600240 scopus 로고    scopus 로고
    • Mineralocorticoid blockade reduces vascular injury in stroke-prone hypertensive rats
    • Rocha R, Chander PN, Khanna K, Zuckerman A, Stier CT Jr. Mineralocorticoid blockade reduces vascular injury in stroke-prone hypertensive rats. Hypertension 31: 451-458, 1998.
    • (1998) Hypertension , vol.31 , pp. 451-458
    • Rocha, R.1    Chander, P.N.2    Khanna, K.3    Zuckerman, A.4    Stier Jr., C.T.5
  • 37
    • 0032921738 scopus 로고    scopus 로고
    • Role of aldosterone in renal vascular injury in stroke-prone hypertensive rats
    • Rocha R, Chander PN, Zuckerman A, Stier CT Jr. Role of aldosterone in renal vascular injury in stroke-prone hypertensive rats. Hypertension 33: 232-237, 1999.
    • (1999) Hypertension , vol.33 , pp. 232-237
    • Rocha, R.1    Chander, P.N.2    Zuckerman, A.3    Stier Jr, C.T.4
  • 38
    • 0033745021 scopus 로고    scopus 로고
    • Stier CT Jr, Kifor I, Ochoa-Maya MR, Rennke HG, Williams GH, Adler GK. Aldosterone: A mediator of myocardial necrosis and renal arteriopathy
    • Rocha R, Stier CT Jr, Kifor I, Ochoa-Maya MR, Rennke HG, Williams GH, Adler GK. Aldosterone: a mediator of myocardial necrosis and renal arteriopathy. Endocrinology 141: 3871-3878, 2000.
    • (2000) Endocrinology , vol.141 , pp. 3871-3878
    • Rocha, R.1
  • 39
    • 25444434147 scopus 로고    scopus 로고
    • Aldosterone stimulates matrix metalloproteinases and reactive oxygen species in adult rat ventricular cardiomyocytes
    • Rude MK, Duhaney TA, Kuster GM, Judge S, Heo J, Colucci WS, Siwik DA, Sam F. Aldosterone stimulates matrix metalloproteinases and reactive oxygen species in adult rat ventricular cardiomyocytes. Hypertension 46: 555-561, 2005.
    • (2005) Hypertension , vol.46 , pp. 555-561
    • Rude, M.K.1    Duhaney, T.A.2    Kuster, G.M.3    Judge, S.4    Heo, J.5    Colucci, W.S.6    Siwik, D.A.7    Sam, F.8
  • 41
    • 3242811296 scopus 로고    scopus 로고
    • Acute renal failure: Definitions, diagnosis, pathogenesis, and therapy
    • Schrier RW, Wang W, Poole B, Mitra A. Acute renal failure: definitions, diagnosis, pathogenesis, and therapy. J Clin Invest 114: 5-14, 2004.
    • (2004) J Clin Invest , vol.114 , pp. 5-14
    • Schrier, R.W.1    Wang, W.2    Poole, B.3    Mitra, A.4
  • 42
    • 3042730959 scopus 로고    scopus 로고
    • eNOS at a glance
    • Sessa WC. eNOS at a glance. J Cell Sci 117: 2427-2429, 2004.
    • (2004) J Cell Sci , vol.117 , pp. 2427-2429
    • Sessa, W.C.1
  • 43
    • 18044380084 scopus 로고    scopus 로고
    • Protective effect of catechin on ischemia-reperfusion-induced renal injury in rats
    • Singh D, Chander V, Chopra K. Protective effect of catechin on ischemia-reperfusion-induced renal injury in rats. Pharmacol Rep 57: 70-76, 2005.
    • (2005) Pharmacol Rep , vol.57 , pp. 70-76
    • Singh, D.1    Chander, V.2    Chopra, K.3
  • 44
    • 4544374648 scopus 로고    scopus 로고
    • Prevention of renal fibrosis by spironolactone in mice with complete unilateral ureteral obstruction
    • Trachtman H, Weiser AC, Valderrama E, Morgado M, Palmer LS. Prevention of renal fibrosis by spironolactone in mice with complete unilateral ureteral obstruction. J Urol 172: 1590-1594, 2004.
    • (2004) J Urol , vol.172 , pp. 1590-1594
    • Trachtman, H.1    Weiser, A.C.2    Valderrama, E.3    Morgado, M.4    Palmer, L.S.5
  • 45
    • 0030999877 scopus 로고    scopus 로고
    • Aldosterone and dexamethasone stimulate calcineurin activity through a transcription-independent mechanism involving steroid receptor- associated heat shock proteins
    • Tumlin JA, Lea JP, Swanson CE, Smith CL, Edge SS, Someren JS. Aldosterone and dexamethasone stimulate calcineurin activity through a transcription-independent mechanism involving steroid receptor- associated heat shock proteins. J Clin Invest 99: 1217-1223, 1997.
    • (1997) J Clin Invest , vol.99 , pp. 1217-1223
    • Tumlin, J.A.1    Lea, J.P.2    Swanson, C.E.3    Smith, C.L.4    Edge, S.S.5    Someren, J.S.6
  • 47
    • 0036791717 scopus 로고    scopus 로고
    • Spironolactone improves angiotensin-induced vascular changes and oxidative stress
    • Virdis A, Neves MF, Amiri F, Viel E, Touyz RM, Schiffrin EL. Spironolactone improves angiotensin-induced vascular changes and oxidative stress. Hypertension 40: 504-510, 2002.
    • (2002) Hypertension , vol.40 , pp. 504-510
    • Virdis, A.1    Neves, M.F.2    Amiri, F.3    Viel, E.4    Touyz, R.M.5    Schiffrin, E.L.6
  • 49
    • 0017115137 scopus 로고
    • A note on the practical aspects of the assay of N-acetyl-beta-glucosaminidase in human urine
    • Wellwood JM, Price RG, Ellis BG, Thompson AE. A note on the practical aspects of the assay of N-acetyl-beta-glucosaminidase in human urine. Clin Chim Acta 69: 85-91, 1976.
    • (1976) Clin Chim Acta , vol.69 , pp. 85-91
    • Wellwood, J.M.1    Price, R.G.2    Ellis, B.G.3    Thompson, A.E.4
  • 51
    • 11844286344 scopus 로고    scopus 로고
    • Endothelial nitric oxide contributes to the renal protective effects of ischemic preconditioning
    • Yamasowa H, Shimizu S, Inoue T, Takaoka M, Matsumura Y. Endothelial nitric oxide contributes to the renal protective effects of ischemic preconditioning. J Pharmacol Exp Ther 312: 153-159, 2005.
    • (2005) J Pharmacol Exp Ther , vol.312 , pp. 153-159
    • Yamasowa, H.1    Shimizu, S.2    Inoue, T.3    Takaoka, M.4    Matsumura, Y.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.