-
1
-
-
84855357959
-
Taste receptor signalling – from tongues to lungs
-
Kinnamon, S.C., Taste receptor signalling – from tongues to lungs. Acta Physiol (Oxf) 204 (2012), 158–168.
-
(2012)
Acta Physiol (Oxf)
, vol.204
, pp. 158-168
-
-
Kinnamon, S.C.1
-
2
-
-
84955326758
-
Bitter taste bodyguards
-
Lee, R.J., Cohen, N.A., Bitter taste bodyguards. Sci Am 314 (2016), 38–43.
-
(2016)
Sci Am
, vol.314
, pp. 38-43
-
-
Lee, R.J.1
Cohen, N.A.2
-
3
-
-
84920647529
-
Taste receptors in innate immunity
-
Lee, R.J., Cohen, N.A., Taste receptors in innate immunity. Cell Mol Life Sci 72 (2015), 217–236.
-
(2015)
Cell Mol Life Sci
, vol.72
, pp. 217-236
-
-
Lee, R.J.1
Cohen, N.A.2
-
4
-
-
84870314938
-
Extraoral bitter taste receptors as mediators of off-target drug effects
-
Clark, A.A., Liggett, S.B., Munger, S.D., Extraoral bitter taste receptors as mediators of off-target drug effects. FASEB J 26 (2012), 4827–4831.
-
(2012)
FASEB J
, vol.26
, pp. 4827-4831
-
-
Clark, A.A.1
Liggett, S.B.2
Munger, S.D.3
-
5
-
-
84961891821
-
Bitter taste receptors: novel insights into the biochemistry and pharmacology
-
Jaggupilli, A., Howard, R., Upadhyaya, J.D., Bhullar, R.P., Chelikani, P., Bitter taste receptors: novel insights into the biochemistry and pharmacology. Int J Biochem Cell Biol 77 (2016), 184–196.
-
(2016)
Int J Biochem Cell Biol
, vol.77
, pp. 184-196
-
-
Jaggupilli, A.1
Howard, R.2
Upadhyaya, J.D.3
Bhullar, R.P.4
Chelikani, P.5
-
6
-
-
84899503308
-
The bitter pill: clinical drugs that activate the human bitter taste receptor TAS2R14
-
Levit, A., Nowak, S., Peters, M., et al. The bitter pill: clinical drugs that activate the human bitter taste receptor TAS2R14. FASEB J 28 (2014), 1181–1197.
-
(2014)
FASEB J
, vol.28
, pp. 1181-1197
-
-
Levit, A.1
Nowak, S.2
Peters, M.3
-
7
-
-
84882909947
-
The bad taste of medicines: overview of basic research on bitter taste
-
Mennella, J.A., Spector, A.C., Reed, D.R., Coldwell, S.E., The bad taste of medicines: overview of basic research on bitter taste. Clin Ther 35 (2013), 1225–1246.
-
(2013)
Clin Ther
, vol.35
, pp. 1225-1246
-
-
Mennella, J.A.1
Spector, A.C.2
Reed, D.R.3
Coldwell, S.E.4
-
8
-
-
84880681249
-
Taste perception: from the tongue to the testis
-
Li, F., Taste perception: from the tongue to the testis. Mol Hum Reprod 19 (2013), 349–360.
-
(2013)
Mol Hum Reprod
, vol.19
, pp. 349-360
-
-
Li, F.1
-
9
-
-
84975726301
-
Sweet taste-sensing receptors expressed in pancreatic β-cells: sweet molecules act as biased agonists
-
Kojima, I., Nakagawa, Y., Ohtsu, Y., Medina, A., Nagasawa, M., Sweet taste-sensing receptors expressed in pancreatic β-cells: sweet molecules act as biased agonists. Endocrinol Metab (Seoul) 29 (2014), 12–19.
-
(2014)
Endocrinol Metab (Seoul)
, vol.29
, pp. 12-19
-
-
Kojima, I.1
Nakagawa, Y.2
Ohtsu, Y.3
Medina, A.4
Nagasawa, M.5
-
10
-
-
84906832000
-
Expression of the glucose-sensing receptor T1R3 in pancreatic islet: changes in the expression levels in various nutritional and metabolic states
-
Medina, A., Nakagawa, Y., Ma, J., et al. Expression of the glucose-sensing receptor T1R3 in pancreatic islet: changes in the expression levels in various nutritional and metabolic states. Endocr J 61 (2014), 797–805.
-
(2014)
Endocr J
, vol.61
, pp. 797-805
-
-
Medina, A.1
Nakagawa, Y.2
Ma, J.3
-
11
-
-
84886993360
-
Multimodal function of the sweet taste receptor expressed in pancreatic β-cells: generation of diverse patterns of intracellular signals by sweet agonists
-
Nakagawa, Y., Nagasawa, M., Mogami, H., Lohse, M., Ninomiya, Y., Kojima, I., Multimodal function of the sweet taste receptor expressed in pancreatic β-cells: generation of diverse patterns of intracellular signals by sweet agonists. Endocr J 60 (2013), 1191–1206.
-
(2013)
Endocr J
, vol.60
, pp. 1191-1206
-
-
Nakagawa, Y.1
Nagasawa, M.2
Mogami, H.3
Lohse, M.4
Ninomiya, Y.5
Kojima, I.6
-
12
-
-
84857426294
-
Sweet taste receptor signaling in beta cells mediates fructose-induced potentiation of glucose-stimulated insulin secretion
-
Kyriazis, G.A., Soundarapandian, M.M., Tyrberg, B., Sweet taste receptor signaling in beta cells mediates fructose-induced potentiation of glucose-stimulated insulin secretion. Proc Natl Acad Sci U S A 109 (2012), E524–E532.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. E524-E532
-
-
Kyriazis, G.A.1
Soundarapandian, M.M.2
Tyrberg, B.3
-
13
-
-
84903823461
-
Gut sweet taste receptors and their role in metabolism
-
Meyer-Gerspach, A.C., Wölnerhanssen, B., Beglinger, C., Gut sweet taste receptors and their role in metabolism. Front Horm Res 42 (2014), 123–133.
-
(2014)
Front Horm Res
, vol.42
, pp. 123-133
-
-
Meyer-Gerspach, A.C.1
Wölnerhanssen, B.2
Beglinger, C.3
-
14
-
-
70349560878
-
Taste signaling elements expressed in gut enteroendocrine cells regulate nutrient-responsive secretion of gut hormones
-
Kokrashvili, Z., Mosinger, B., Margolskee, R.F., Taste signaling elements expressed in gut enteroendocrine cells regulate nutrient-responsive secretion of gut hormones. Am J Clin Nutr 90 (2009), 822S–825S.
-
(2009)
Am J Clin Nutr
, vol.90
, pp. 822S-825S
-
-
Kokrashvili, Z.1
Mosinger, B.2
Margolskee, R.F.3
-
15
-
-
14644415512
-
Expression of sweet taste receptors of the T1R family in the intestinal tract and enteroendocrine cells
-
Dyer, J., Salmon, K.S., Zibrik, L., Shirazi-Beechey, S.P., Expression of sweet taste receptors of the T1R family in the intestinal tract and enteroendocrine cells. Biochem Soc Trans 33 (2005), 302–305.
-
(2005)
Biochem Soc Trans
, vol.33
, pp. 302-305
-
-
Dyer, J.1
Salmon, K.S.2
Zibrik, L.3
Shirazi-Beechey, S.P.4
-
16
-
-
84871129066
-
Functional characterization of bitter-taste receptors expressed in mammalian testis
-
Xu, J., Cao, J., Iguchi, N., Riethmacher, D., Huang, L., Functional characterization of bitter-taste receptors expressed in mammalian testis. Mol Hum Reprod 19 (2013), 17–28.
-
(2013)
Mol Hum Reprod
, vol.19
, pp. 17-28
-
-
Xu, J.1
Cao, J.2
Iguchi, N.3
Riethmacher, D.4
Huang, L.5
-
17
-
-
84880656949
-
Genetic loss or pharmacological blockade of testes-expressed taste genes causes male sterility
-
Mosinger, B., Redding, K.M., Parker, M.R., et al. Genetic loss or pharmacological blockade of testes-expressed taste genes causes male sterility. Proc Natl Acad Sci U S A 110 (2013), 12319–12324.
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, pp. 12319-12324
-
-
Mosinger, B.1
Redding, K.M.2
Parker, M.R.3
-
18
-
-
84861754565
-
Depletion of bitter taste transduction leads to massive spermatid loss in transgenic mice
-
Li, F., Zhou, M., Depletion of bitter taste transduction leads to massive spermatid loss in transgenic mice. Mol Hum Reprod 18 (2012), 289–297.
-
(2012)
Mol Hum Reprod
, vol.18
, pp. 289-297
-
-
Li, F.1
Zhou, M.2
-
19
-
-
84903746597
-
Genetics of taste receptors
-
Bachmanov, A.A., Bosak, N.P., Lin, C., et al. Genetics of taste receptors. Curr Pharm Des 20 (2014), 2669–2683.
-
(2014)
Curr Pharm Des
, vol.20
, pp. 2669-2683
-
-
Bachmanov, A.A.1
Bosak, N.P.2
Lin, C.3
-
20
-
-
33645799951
-
Teaching resources. Sensory systems: taste perception
-
Margolskee, R.F., Teaching resources. Sensory systems: taste perception. Sci STKE, 2005, 2005, tr20.
-
(2005)
Sci STKE
, vol.2005
, pp. tr20
-
-
Margolskee, R.F.1
-
21
-
-
57049179732
-
Involvement of T1R3 in calcium-magnesium taste
-
Tordoff, M.G., Shao, H., Alarcón, L.K., et al. Involvement of T1R3 in calcium-magnesium taste. Physiol Genomics 34 (2008), 338–348.
-
(2008)
Physiol Genomics
, vol.34
, pp. 338-348
-
-
Tordoff, M.G.1
Shao, H.2
Alarcón, L.K.3
-
22
-
-
84896491736
-
2+ signaling in human taste bud cells mediates differential responses to fatty acids and is altered in obese mice
-
2+ signaling in human taste bud cells mediates differential responses to fatty acids and is altered in obese mice. Gastroenterology 146 (2014), 995–1005.
-
(2014)
Gastroenterology
, vol.146
, pp. 995-1005
-
-
Ozdener, M.H.1
Subramaniam, S.2
Sundaresan, S.3
-
23
-
-
77954134133
-
Taste preference for fatty acids is mediated by GPR40 and GPR120
-
Cartoni, C., Yasumatsu, K., Ohkuri, T., et al. Taste preference for fatty acids is mediated by GPR40 and GPR120. J Neurosci 30 (2010), 8376–8382.
-
(2010)
J Neurosci
, vol.30
, pp. 8376-8382
-
-
Cartoni, C.1
Yasumatsu, K.2
Ohkuri, T.3
-
24
-
-
60549103018
-
Oro-sensory perception of dietary lipids: new insights into the fat taste transduction
-
Khan, N.A., Besnard, P., Oro-sensory perception of dietary lipids: new insights into the fat taste transduction. Biochim Biophys Acta 1791 (2009), 149–155.
-
(2009)
Biochim Biophys Acta
, vol.1791
, pp. 149-155
-
-
Khan, N.A.1
Besnard, P.2
-
25
-
-
35148868260
-
Fat and carbohydrate preferences in mice: the contribution of alpha-gustducin and Trpm5 taste-signaling proteins
-
Sclafani, A., Zukerman, S., Glendinning, J.I., Margolskee, R.F., Fat and carbohydrate preferences in mice: the contribution of alpha-gustducin and Trpm5 taste-signaling proteins. Am J Physiol Regul Integr Comp Physiol 293 (2007), R1504–R1513.
-
(2007)
Am J Physiol Regul Integr Comp Physiol
, vol.293
, pp. R1504-R1513
-
-
Sclafani, A.1
Zukerman, S.2
Glendinning, J.I.3
Margolskee, R.F.4
-
26
-
-
27644533906
-
CD36 involvement in orosensory detection of dietary lipids, spontaneous fat preference, and digestive secretions
-
Laugerette, F., Passilly-Degrace, P., Patris, B., et al. CD36 involvement in orosensory detection of dietary lipids, spontaneous fat preference, and digestive secretions. J Clin Invest 115 (2005), 3177–3184.
-
(2005)
J Clin Invest
, vol.115
, pp. 3177-3184
-
-
Laugerette, F.1
Passilly-Degrace, P.2
Patris, B.3
-
27
-
-
84874359134
-
High salt recruits aversive taste pathways
-
Oka, Y., Butnaru, M., von Buchholtz, L., Ryba, N.J., Zuker, C.S., High salt recruits aversive taste pathways. Nature 494 (2013), 472–475.
-
(2013)
Nature
, vol.494
, pp. 472-475
-
-
Oka, Y.1
Butnaru, M.2
von Buchholtz, L.3
Ryba, N.J.4
Zuker, C.S.5
-
28
-
-
77956165390
-
GPR120 is an omega-3 fatty acid receptor mediating potent anti-inflammatory and insulin-sensitizing effects
-
Oh, D.Y., Talukdar, S., Bae, E.J., et al. GPR120 is an omega-3 fatty acid receptor mediating potent anti-inflammatory and insulin-sensitizing effects. Cell. 142 (2010), 687–698.
-
(2010)
Cell.
, vol.142
, pp. 687-698
-
-
Oh, D.Y.1
Talukdar, S.2
Bae, E.J.3
-
29
-
-
84875635849
-
Oral and extra-oral taste perception
-
Yamamoto, K., Ishimaru, Y., Oral and extra-oral taste perception. Semin Cell Dev Biol 24 (2013), 240–246.
-
(2013)
Semin Cell Dev Biol
, vol.24
, pp. 240-246
-
-
Yamamoto, K.1
Ishimaru, Y.2
-
30
-
-
84903696086
-
Taste transductions in taste receptor cells: basic tastes and moreover
-
Iwata, S., Yoshida, R., Ninomiya, Y., Taste transductions in taste receptor cells: basic tastes and moreover. Curr Pharm Des 20 (2014), 2684–2692.
-
(2014)
Curr Pharm Des
, vol.20
, pp. 2684-2692
-
-
Iwata, S.1
Yoshida, R.2
Ninomiya, Y.3
-
31
-
-
84920874768
-
Role of the bitter taste receptor T2R38 in upper respiratory infection and chronic rhinosinusitis
-
Lee, R.J., Cohen, N.A., Role of the bitter taste receptor T2R38 in upper respiratory infection and chronic rhinosinusitis. Curr Opin Allergy Clin Immunol 15 (2015), 14–20.
-
(2015)
Curr Opin Allergy Clin Immunol
, vol.15
, pp. 14-20
-
-
Lee, R.J.1
Cohen, N.A.2
-
32
-
-
84914153160
-
Bitter and sweet taste receptors in the respiratory epithelium in health and disease
-
Lee, R.J., Cohen, N.A., Bitter and sweet taste receptors in the respiratory epithelium in health and disease. J Mol Med (Berl) 92 (2014), 1235–1244.
-
(2014)
J Mol Med (Berl)
, vol.92
, pp. 1235-1244
-
-
Lee, R.J.1
Cohen, N.A.2
-
33
-
-
4043143509
-
The sweet and the bitter of mammalian taste
-
Scott, K., The sweet and the bitter of mammalian taste. Curr Opin Neurobiol 14 (2004), 423–427.
-
(2004)
Curr Opin Neurobiol
, vol.14
, pp. 423-427
-
-
Scott, K.1
-
34
-
-
0035839040
-
Mammalian sweet taste receptors
-
Nelson, G., Hoon, M.A., Chandrashekar, J., Zhang, Y., Ryba, N.J., Zuker, C.S., Mammalian sweet taste receptors. Cell 106 (2001), 381–390.
-
(2001)
Cell
, vol.106
, pp. 381-390
-
-
Nelson, G.1
Hoon, M.A.2
Chandrashekar, J.3
Zhang, Y.4
Ryba, N.J.5
Zuker, C.S.6
-
35
-
-
84896899700
-
Glucose promotes its own metabolism by acting on the cell-surface glucose-sensing receptor T1R3
-
Nakagawa, Y., Ohtsu, Y., Nagasawa, M., Shibata, H., Kojima, I., Glucose promotes its own metabolism by acting on the cell-surface glucose-sensing receptor T1R3. Endocr J 61 (2014), 119–131.
-
(2014)
Endocr J
, vol.61
, pp. 119-131
-
-
Nakagawa, Y.1
Ohtsu, Y.2
Nagasawa, M.3
Shibata, H.4
Kojima, I.5
-
36
-
-
84872392828
-
A novel regulatory function of sweet taste-sensing receptor in adipogenic differentiation of 3T3-L1 cells
-
Masubuchi, Y., Nakagawa, Y., Ma, J., et al. A novel regulatory function of sweet taste-sensing receptor in adipogenic differentiation of 3T3-L1 cells. PLoS One, 8, 2013, e54500.
-
(2013)
PLoS One
, vol.8
, pp. e54500
-
-
Masubuchi, Y.1
Nakagawa, Y.2
Ma, J.3
-
37
-
-
84893051272
-
Diet shapes the evolution of the vertebrate bitter taste receptor gene repertoire
-
Li, D., Zhang, J., Diet shapes the evolution of the vertebrate bitter taste receptor gene repertoire. Mol Biol Evol 31 (2014), 303–309.
-
(2014)
Mol Biol Evol
, vol.31
, pp. 303-309
-
-
Li, D.1
Zhang, J.2
-
38
-
-
84978401133
-
Comprehensive analysis of mouse bitter taste receptors reveals different molecular receptive ranges for orthologous receptors in mice and humans
-
Lossow, K., Hübner, S., Roudnitzky, N., et al. Comprehensive analysis of mouse bitter taste receptors reveals different molecular receptive ranges for orthologous receptors in mice and humans. J Biol Chem 291 (2016), 15358–15377.
-
(2016)
J Biol Chem
, vol.291
, pp. 15358-15377
-
-
Lossow, K.1
Hübner, S.2
Roudnitzky, N.3
-
39
-
-
77950114281
-
The molecular receptive ranges of human TAS2R bitter taste receptors
-
Meyerhof, W., Batram, C., Kuhn, C., et al. The molecular receptive ranges of human TAS2R bitter taste receptors. Chem Senses 35 (2010), 157–170.
-
(2010)
Chem Senses
, vol.35
, pp. 157-170
-
-
Meyerhof, W.1
Batram, C.2
Kuhn, C.3
-
40
-
-
84895487775
-
Peripheral coding of taste
-
Liman, E.R., Zhang, Y.V., Montell, C., Peripheral coding of taste. Neuron 81 (2014), 984–1000.
-
(2014)
Neuron
, vol.81
, pp. 984-1000
-
-
Liman, E.R.1
Zhang, Y.V.2
Montell, C.3
-
41
-
-
84954561117
-
Intestinal epithelial tuft cells initiate type 2 mucosal immunity to helminth parasites
-
Gerbe, F., Sidot, E., Smyth, D.J., et al. Intestinal epithelial tuft cells initiate type 2 mucosal immunity to helminth parasites. Nature 529 (2016), 226–230.
-
(2016)
Nature
, vol.529
, pp. 226-230
-
-
Gerbe, F.1
Sidot, E.2
Smyth, D.J.3
-
42
-
-
84958767810
-
Tuft cells, taste-chemosensory cells, orchestrate parasite type 2 immunity in the gut
-
Howitt, M.R., Lavoie, S., Michaud, M., et al. Tuft cells, taste-chemosensory cells, orchestrate parasite type 2 immunity in the gut. Science 351 (2016), 1329–1333.
-
(2016)
Science
, vol.351
, pp. 1329-1333
-
-
Howitt, M.R.1
Lavoie, S.2
Michaud, M.3
-
43
-
-
84879700974
-
Solitary chemosensory cells and bitter taste receptor signaling in human sinonasal mucosa
-
Barham, H.P., Cooper, S.E., Anderson, C.B., et al. Solitary chemosensory cells and bitter taste receptor signaling in human sinonasal mucosa. Int Forum Allergy Rhinol 3 (2013), 450–457.
-
(2013)
Int Forum Allergy Rhinol
, vol.3
, pp. 450-457
-
-
Barham, H.P.1
Cooper, S.E.2
Anderson, C.B.3
-
44
-
-
78651282172
-
Expression of taste receptors in solitary chemosensory cells of rodent airways
-
Tizzano, M., Cristofoletti, M., Sbarbati, A., Finger, T.E., Expression of taste receptors in solitary chemosensory cells of rodent airways. BMC Pulm Med, 11, 2011, 3.
-
(2011)
BMC Pulm Med
, vol.11
, pp. 3
-
-
Tizzano, M.1
Cristofoletti, M.2
Sbarbati, A.3
Finger, T.E.4
-
45
-
-
85028923546
-
Bacterial D-amino acids suppress sinonasal innate immunity through sweet taste receptors in solitary chemosensory cells
-
Lee, R.J., Hariri, B.M., McMahon, D.B., et al. Bacterial D-amino acids suppress sinonasal innate immunity through sweet taste receptors in solitary chemosensory cells. Sci Signal, 10, 2017.
-
(2017)
Sci Signal
, vol.10
-
-
Lee, R.J.1
Hariri, B.M.2
McMahon, D.B.3
-
46
-
-
84896770768
-
Bitter and sweet taste receptors regulate human upper respiratory innate immunity
-
Lee, R.J., Kofonow, J.M., Rosen, P.L., et al. Bitter and sweet taste receptors regulate human upper respiratory innate immunity. J Clin Invest 124 (2014), 1393–1405.
-
(2014)
J Clin Invest
, vol.124
, pp. 1393-1405
-
-
Lee, R.J.1
Kofonow, J.M.2
Rosen, P.L.3
-
47
-
-
84859450268
-
Major taste loss in carnivorous mammals
-
Jiang, P., Josue, J., Li, X., et al. Major taste loss in carnivorous mammals. Proc Natl Acad Sci U S A 109 (2012), 4956–4961.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 4956-4961
-
-
Jiang, P.1
Josue, J.2
Li, X.3
-
48
-
-
17844382462
-
Genetic and environmental determinants of bitter perception and sweet preferences
-
Mennella, J.A., Pepino, M.Y., Reed, D.R., Genetic and environmental determinants of bitter perception and sweet preferences. Pediatrics 115 (2005), e216–e222.
-
(2005)
Pediatrics
, vol.115
, pp. e216-e222
-
-
Mennella, J.A.1
Pepino, M.Y.2
Reed, D.R.3
-
49
-
-
13944250257
-
The molecular basis of individual differences in phenylthiocarbamide and propylthiouracil bitterness perception
-
Bufe, B., Breslin, P.A., Kuhn, C., et al. The molecular basis of individual differences in phenylthiocarbamide and propylthiouracil bitterness perception. Curr Biol 15 (2005), 322–327.
-
(2005)
Curr Biol
, vol.15
, pp. 322-327
-
-
Bufe, B.1
Breslin, P.A.2
Kuhn, C.3
-
50
-
-
84864246506
-
3D structure prediction of TAS2R38 bitter receptors bound to agonists phenylthiocarbamide (PTC) and 6-n-propylthiouracil (PROP)
-
Tan, J., Abrol, R., Trzaskowski, B., Goddard, W.A., 3D structure prediction of TAS2R38 bitter receptors bound to agonists phenylthiocarbamide (PTC) and 6-n-propylthiouracil (PROP). J Chem Inf Model 52 (2012), 1875–1885.
-
(2012)
J Chem Inf Model
, vol.52
, pp. 1875-1885
-
-
Tan, J.1
Abrol, R.2
Trzaskowski, B.3
Goddard, W.A.4
-
51
-
-
77957871915
-
Insights into the binding of phenylthiocarbamide (PTC) agonist to its target human TAS2R38 bitter receptor
-
Biarnés, X., Marchiori, A., Giorgetti, A., et al. Insights into the binding of phenylthiocarbamide (PTC) agonist to its target human TAS2R38 bitter receptor. PLoS One, 5, 2010, e12394.
-
(2010)
PLoS One
, vol.5
, pp. e12394
-
-
Biarnés, X.1
Marchiori, A.2
Giorgetti, A.3
-
52
-
-
33749240615
-
Modeling the human PTC bitter-taste receptor interactions with bitter tastants
-
Floriano, W.B., Hall, S., Vaidehi, N., Kim, U., Drayna, D., Goddard, W.A., Modeling the human PTC bitter-taste receptor interactions with bitter tastants. J Mol Model 12 (2006), 931–941.
-
(2006)
J Mol Model
, vol.12
, pp. 931-941
-
-
Floriano, W.B.1
Hall, S.2
Vaidehi, N.3
Kim, U.4
Drayna, D.5
Goddard, W.A.6
-
53
-
-
84884872511
-
Human bitter perception correlates with bitter receptor messenger RNA expression in taste cells
-
Lipchock, S.V., Mennella, J.A., Spielman, A.I., Reed, D.R., Human bitter perception correlates with bitter receptor messenger RNA expression in taste cells. Am J Clin Nutr 98 (2013), 1136–1143.
-
(2013)
Am J Clin Nutr
, vol.98
, pp. 1136-1143
-
-
Lipchock, S.V.1
Mennella, J.A.2
Spielman, A.I.3
Reed, D.R.4
-
54
-
-
84966356381
-
Global diversity in the TAS2R38 bitter taste receptor: revisiting a classic evolutionary PROPosal
-
Risso, D.S., Mezzavilla, M., Pagani, L., et al. Global diversity in the TAS2R38 bitter taste receptor: revisiting a classic evolutionary PROPosal. Sci Rep, 6, 2016, 25506.
-
(2016)
Sci Rep
, vol.6
, pp. 25506
-
-
Risso, D.S.1
Mezzavilla, M.2
Pagani, L.3
-
55
-
-
84995799664
-
A review of the associations between single nucleotide polymorphisms in taste receptors, eating behaviors, and health
-
Chamoun, E., Mutch, D.M., Allen-Vercoe, E., et al. A review of the associations between single nucleotide polymorphisms in taste receptors, eating behaviors, and health. Crit Rev Food Sci Nutr 58 (2018), 194–207.
-
(2018)
Crit Rev Food Sci Nutr
, vol.58
, pp. 194-207
-
-
Chamoun, E.1
Mutch, D.M.2
Allen-Vercoe, E.3
-
56
-
-
84958982886
-
Sweet taste receptor TAS1R2 polymorphism (Val191Val) is associated with a higher carbohydrate intake and hypertriglyceridemia among the population of west Mexico
-
Ramos-Lopez, O., Panduro, A., Martinez-Lopez, E., Roman, S., Sweet taste receptor TAS1R2 polymorphism (Val191Val) is associated with a higher carbohydrate intake and hypertriglyceridemia among the population of west Mexico. Nutrients, 8, 2016, 101.
-
(2016)
Nutrients
, vol.8
, pp. 101
-
-
Ramos-Lopez, O.1
Panduro, A.2
Martinez-Lopez, E.3
Roman, S.4
-
57
-
-
65249129179
-
Sweet taste receptor expressed in pancreatic beta-cells activates the calcium and cyclic AMP signaling systems and stimulates insulin secretion
-
Nakagawa, Y., Nagasawa, M., Yamada, S., et al. Sweet taste receptor expressed in pancreatic beta-cells activates the calcium and cyclic AMP signaling systems and stimulates insulin secretion. PLoS One, 4, 2009, e5106.
-
(2009)
PLoS One
, vol.4
, pp. e5106
-
-
Nakagawa, Y.1
Nagasawa, M.2
Yamada, S.3
-
58
-
-
0032213167
-
Effects of artificial sweeteners on insulin release and cationic fluxes in rat pancreatic islets
-
Malaisse, W.J., Vanonderbergen, A., Louchami, K., Jijakli, H., Malaisse-Lagae, F., Effects of artificial sweeteners on insulin release and cationic fluxes in rat pancreatic islets. Cell Signal 10 (1998), 727–733.
-
(1998)
Cell Signal
, vol.10
, pp. 727-733
-
-
Malaisse, W.J.1
Vanonderbergen, A.2
Louchami, K.3
Jijakli, H.4
Malaisse-Lagae, F.5
-
59
-
-
84886820170
-
Glucose sensing mechanisms in hypothalamic cell models: glucose inhibition of AgRP synthesis and secretion
-
Chalmers, J.A., Jang, J.J., Belsham, D.D., Glucose sensing mechanisms in hypothalamic cell models: glucose inhibition of AgRP synthesis and secretion. Mol Cell Endocrinol 382 (2014), 262–270.
-
(2014)
Mol Cell Endocrinol
, vol.382
, pp. 262-270
-
-
Chalmers, J.A.1
Jang, J.J.2
Belsham, D.D.3
-
60
-
-
84865770759
-
Neuronal expression of bitter taste receptors and downstream signaling molecules in the rat brainstem
-
Dehkordi, O., Rose, J.E., Fatemi, M., et al. Neuronal expression of bitter taste receptors and downstream signaling molecules in the rat brainstem. Brain Res 1475 (2012), 1–10.
-
(2012)
Brain Res
, vol.1475
, pp. 1-10
-
-
Dehkordi, O.1
Rose, J.E.2
Fatemi, M.3
-
61
-
-
65649131584
-
Contribution of the T1r3 taste receptor to the response properties of central gustatory neurons
-
Lemon, C.H., Margolskee, R.F., Contribution of the T1r3 taste receptor to the response properties of central gustatory neurons. J Neurophysiol 101 (2009), 2459–2471.
-
(2009)
J Neurophysiol
, vol.101
, pp. 2459-2471
-
-
Lemon, C.H.1
Margolskee, R.F.2
-
62
-
-
72449180982
-
Sweet taste signaling functions as a hypothalamic glucose sensor
-
Ren, X., Zhou, L., Terwilliger, R., Newton, S.S., de Araujo, I.E., Sweet taste signaling functions as a hypothalamic glucose sensor. Front Integr Neurosci, 3, 2009, 12.
-
(2009)
Front Integr Neurosci
, vol.3
, pp. 12
-
-
Ren, X.1
Zhou, L.2
Terwilliger, R.3
Newton, S.S.4
de Araujo, I.E.5
-
63
-
-
85023615613
-
Altered learning, memory, and social behavior in type 1 taste receptor subunit 3 knock-out mice are associated with neuronal dysfunction
-
Martin, B., Wang, R., Cong, W.N., et al. Altered learning, memory, and social behavior in type 1 taste receptor subunit 3 knock-out mice are associated with neuronal dysfunction. J Biol Chem 292 (2017), 11508–11530.
-
(2017)
J Biol Chem
, vol.292
, pp. 11508-11530
-
-
Martin, B.1
Wang, R.2
Cong, W.N.3
-
64
-
-
69549084858
-
Motile cilia of human airway epithelia are chemosensory
-
Shah, A.S., Ben-Shahar, Y., Moninger, T.O., Kline, J.N., Welsh, M.J., Motile cilia of human airway epithelia are chemosensory. Science 325 (2009), 1131–1134.
-
(2009)
Science
, vol.325
, pp. 1131-1134
-
-
Shah, A.S.1
Ben-Shahar, Y.2
Moninger, T.O.3
Kline, J.N.4
Welsh, M.J.5
-
65
-
-
84907058830
-
Mouse nasal epithelial innate immune responses to Pseudomonas aeruginosa quorum-sensing molecules require taste signaling components
-
Lee, R.J., Chen, B., Redding, K.M., Margolskee, R.F., Cohen, N.A., Mouse nasal epithelial innate immune responses to Pseudomonas aeruginosa quorum-sensing molecules require taste signaling components. Innate Immun 20 (2014), 606–617.
-
(2014)
Innate Immun
, vol.20
, pp. 606-617
-
-
Lee, R.J.1
Chen, B.2
Redding, K.M.3
Margolskee, R.F.4
Cohen, N.A.5
-
66
-
-
84883441174
-
The emerging role of the bitter taste receptor T2R38 in upper respiratory infection and chronic rhinosinusitis
-
Lee, R.J., Cohen, N.A., The emerging role of the bitter taste receptor T2R38 in upper respiratory infection and chronic rhinosinusitis. Am J Rhinol Allergy 27 (2013), 283–286.
-
(2013)
Am J Rhinol Allergy
, vol.27
, pp. 283-286
-
-
Lee, R.J.1
Cohen, N.A.2
-
67
-
-
84868610108
-
T2R38 taste receptor polymorphisms underlie susceptibility to upper respiratory infection
-
Lee, R.J., Xiong, G., Kofonow, J.M., et al. T2R38 taste receptor polymorphisms underlie susceptibility to upper respiratory infection. J Clin Invest 122 (2012), 4145–4159.
-
(2012)
J Clin Invest
, vol.122
, pp. 4145-4159
-
-
Lee, R.J.1
Xiong, G.2
Kofonow, J.M.3
-
68
-
-
0036194724
-
Mucus clearance as a primary innate defense mechanism for mammalian airways
-
Knowles, M.R., Boucher, R.C., Mucus clearance as a primary innate defense mechanism for mammalian airways. J Clin Invest 109 (2002), 571–577.
-
(2002)
J Clin Invest
, vol.109
, pp. 571-577
-
-
Knowles, M.R.1
Boucher, R.C.2
-
69
-
-
85040201361
-
Protease-activated receptor 2 activates airway apical membrane chloride permeability and increases ciliary beating
-
McMahon, D.B., Workman, A.D., Kohanski, M.A., et al. Protease-activated receptor 2 activates airway apical membrane chloride permeability and increases ciliary beating. FASEB J 32 (2018), 155–167.
-
(2018)
FASEB J
, vol.32
, pp. 155-167
-
-
McMahon, D.B.1
Workman, A.D.2
Kohanski, M.A.3
-
70
-
-
84986880488
-
New insights into upper airway innate immunity
-
Hariri, B.M., Cohen, N.A., New insights into upper airway innate immunity. Am J Rhinol Allergy 30 (2016), 319–323.
-
(2016)
Am J Rhinol Allergy
, vol.30
, pp. 319-323
-
-
Hariri, B.M.1
Cohen, N.A.2
-
71
-
-
33748923448
-
Sinonasal mucociliary clearance in health and disease
-
Cohen, N.A., Sinonasal mucociliary clearance in health and disease. Ann Otol Rhinol Laryngol Suppl 196 (2006), 20–26.
-
(2006)
Ann Otol Rhinol Laryngol Suppl
, vol.196
, pp. 20-26
-
-
Cohen, N.A.1
-
72
-
-
33947367829
-
Regulation of mammalian ciliary beating
-
Salathe, M., Regulation of mammalian ciliary beating. Annu Rev Physiol 69 (2007), 401–422.
-
(2007)
Annu Rev Physiol
, vol.69
, pp. 401-422
-
-
Salathe, M.1
-
73
-
-
84863403706
-
Proteomic analysis of mammalian primary cilia
-
Ishikawa, H., Thompson, J., Yates, J.R., Marshall, W.F., Proteomic analysis of mammalian primary cilia. Curr Biol 22 (2012), 414–419.
-
(2012)
Curr Biol
, vol.22
, pp. 414-419
-
-
Ishikawa, H.1
Thompson, J.2
Yates, J.R.3
Marshall, W.F.4
-
74
-
-
85015781860
-
Nitric oxide production is stimulated by bitter taste receptors ubiquitously expressed in the sinonasal cavity
-
Yan, C.H., Hahn, S., McMahon, D., et al. Nitric oxide production is stimulated by bitter taste receptors ubiquitously expressed in the sinonasal cavity. Am J Rhinol Allergy 31 (2017), 85–92.
-
(2017)
Am J Rhinol Allergy
, vol.31
, pp. 85-92
-
-
Yan, C.H.1
Hahn, S.2
McMahon, D.3
-
75
-
-
85019593482
-
Flavones modulate respiratory epithelial innate immunity: anti-inflammatory effects and activation of the T2R14 receptor
-
Hariri, B.M., McMahon, D.B., Chen, B., et al. Flavones modulate respiratory epithelial innate immunity: anti-inflammatory effects and activation of the T2R14 receptor. J Biol Chem 292 (2017), 8484–8497.
-
(2017)
J Biol Chem
, vol.292
, pp. 8484-8497
-
-
Hariri, B.M.1
McMahon, D.B.2
Chen, B.3
-
76
-
-
0030739789
-
Nitric oxide and antimicrobial activity of reactive oxygen intermediates
-
Marcinkiewicz, J., Nitric oxide and antimicrobial activity of reactive oxygen intermediates. Immunopharmacology 37 (1997), 35–41.
-
(1997)
Immunopharmacology
, vol.37
, pp. 35-41
-
-
Marcinkiewicz, J.1
-
77
-
-
0031570501
-
Perspectives series: host/pathogen interactions. Mechanisms of nitric oxide-related antimicrobial activity
-
Fang, F.C., Perspectives series: host/pathogen interactions. Mechanisms of nitric oxide-related antimicrobial activity. J Clin Invest 99 (1997), 2818–2825.
-
(1997)
J Clin Invest
, vol.99
, pp. 2818-2825
-
-
Fang, F.C.1
-
78
-
-
85031700434
-
Plant flavones enhance antimicrobial activity of respiratory epithelial cell secretions against Pseudomonas aeruginosa
-
Hariri, B.M., McMahon, D.B., Chen, B., et al. Plant flavones enhance antimicrobial activity of respiratory epithelial cell secretions against Pseudomonas aeruginosa. PLoS One, 12, 2017, e0185203.
-
(2017)
PLoS One
, vol.12
, pp. e0185203
-
-
Hariri, B.M.1
McMahon, D.B.2
Chen, B.3
-
79
-
-
84979710925
-
In vitro effects of anthocyanidins on sinonasal epithelial nitric oxide production and bacterial physiology
-
Hariri, B.M., Payne, S.J., Chen, B., et al. In vitro effects of anthocyanidins on sinonasal epithelial nitric oxide production and bacterial physiology. Am J Rhinol Allergy 30 (2016), 261–268.
-
(2016)
Am J Rhinol Allergy
, vol.30
, pp. 261-268
-
-
Hariri, B.M.1
Payne, S.J.2
Chen, B.3
-
80
-
-
85019868984
-
Relative susceptibility of airway organisms to antimicrobial effects of nitric oxide
-
Workman, A.D., Carey, R.M., Kohanski, M.A., et al. Relative susceptibility of airway organisms to antimicrobial effects of nitric oxide. Int Forum Allergy Rhinol 7 (2017), 770–776.
-
(2017)
Int Forum Allergy Rhinol
, vol.7
, pp. 770-776
-
-
Workman, A.D.1
Carey, R.M.2
Kohanski, M.A.3
-
81
-
-
84866617309
-
Quorum sensing: how bacteria can coordinate activity and synchronize their response to external signals
-
Li, Z., Nair, S.K., Quorum sensing: how bacteria can coordinate activity and synchronize their response to external signals. Protein Sci 21 (2012), 1403–1417.
-
(2012)
Protein Sci
, vol.21
, pp. 1403-1417
-
-
Li, Z.1
Nair, S.K.2
-
82
-
-
80051626877
-
Innate immunity in the respiratory epithelium
-
Parker, D., Prince, A., Innate immunity in the respiratory epithelium. Am J Respir Cell Mol Biol 45 (2011), 189–201.
-
(2011)
Am J Respir Cell Mol Biol
, vol.45
, pp. 189-201
-
-
Parker, D.1
Prince, A.2
-
83
-
-
84896740586
-
Host-microbial interactions in patients with chronic rhinosinusitis
-
Hamilos, D.L., Host-microbial interactions in patients with chronic rhinosinusitis. J Allergy Clin Immunol 133 (2014), 640–653.
-
(2014)
J Allergy Clin Immunol
, vol.133
, pp. 640-653
-
-
Hamilos, D.L.1
-
84
-
-
84951973395
-
Chronic rhinosinusitis pathogenesis
-
Stevens, W.W., Lee, R.J., Schleimer, R.P., Cohen, N.A., Chronic rhinosinusitis pathogenesis. J Allergy Clin Immunol 136 (2015), 1442–1453.
-
(2015)
J Allergy Clin Immunol
, vol.136
, pp. 1442-1453
-
-
Stevens, W.W.1
Lee, R.J.2
Schleimer, R.P.3
Cohen, N.A.4
-
85
-
-
26444491047
-
Resistance to antibiotics: are we in the post-antibiotic era
-
Alanis, A.J., Resistance to antibiotics: are we in the post-antibiotic era. Arch Med Res 36 (2005), 697–705.
-
(2005)
Arch Med Res
, vol.36
, pp. 697-705
-
-
Alanis, A.J.1
-
86
-
-
0037024691
-
National Ambulatory Medical Care Survey: 2000 summary
-
Cherry, D.K., Woodwell, D.A., National Ambulatory Medical Care Survey: 2000 summary. Adv Data, 2002, 1–32.
-
(2002)
Adv Data
, pp. 1-32
-
-
Cherry, D.K.1
Woodwell, D.A.2
-
87
-
-
0037019117
-
National Hospital Ambulatory Medical Care Survey: 2000 outpatient department summary
-
Ly, N., McCaig, L.F., National Hospital Ambulatory Medical Care Survey: 2000 outpatient department summary. Adv Data, 2002, 1–27.
-
(2002)
Adv Data
, pp. 1-27
-
-
Ly, N.1
McCaig, L.F.2
-
88
-
-
0033017152
-
Healthcare expenditures for sinusitis in 1996: contributions of asthma, rhinitis, and other airway disorders
-
Ray, N.F., Baraniuk, J.N., Thamer, M., et al. Healthcare expenditures for sinusitis in 1996: contributions of asthma, rhinitis, and other airway disorders. J Allergy Clin Immunol 103 (1999), 408–414.
-
(1999)
J Allergy Clin Immunol
, vol.103
, pp. 408-414
-
-
Ray, N.F.1
Baraniuk, J.N.2
Thamer, M.3
-
89
-
-
84858815725
-
Recurrent acute rhinosinusitis: epidemiology and health care cost burden
-
Bhattacharyya, N., Grebner, J., Martinson, N.G., Recurrent acute rhinosinusitis: epidemiology and health care cost burden. Otolaryngol Head Neck Surg 146 (2012), 307–312.
-
(2012)
Otolaryngol Head Neck Surg
, vol.146
, pp. 307-312
-
-
Bhattacharyya, N.1
Grebner, J.2
Martinson, N.G.3
-
90
-
-
84882967387
-
Antibiotic resistance: a “dark side” of biofilm-associated chronic infections
-
Marcinkiewicz, J., Strus, M., Pasich, E., Antibiotic resistance: a “dark side” of biofilm-associated chronic infections. Pol Arch Med Wewn 123 (2013), 309–313.
-
(2013)
Pol Arch Med Wewn
, vol.123
, pp. 309-313
-
-
Marcinkiewicz, J.1
Strus, M.2
Pasich, E.3
-
91
-
-
84890962955
-
Chronic rhinosinusitis and antibiotics: the good, the bad, and the ugly
-
Kennedy, J.L., Borish, L., Chronic rhinosinusitis and antibiotics: the good, the bad, and the ugly. Am J Rhinol Allergy 27 (2013), 467–472.
-
(2013)
Am J Rhinol Allergy
, vol.27
, pp. 467-472
-
-
Kennedy, J.L.1
Borish, L.2
-
92
-
-
84878251319
-
Chapter 4: chronic rhinosinusitis
-
Settipane, R.A., Peters, A.T., Chandra, R., Chapter 4: chronic rhinosinusitis. Am J Rhinol Allergy 27:suppl 1 (2013), S11–S15.
-
(2013)
Am J Rhinol Allergy
, vol.27
, pp. S11-S15
-
-
Settipane, R.A.1
Peters, A.T.2
Chandra, R.3
-
93
-
-
84858678454
-
Bacteriology and antibiotic resistance in chronic rhinosinusitis
-
Manes, R.P., Batra, P.S., Bacteriology and antibiotic resistance in chronic rhinosinusitis. Facial Plast Surg Clin North Am 20 (2012), 87–91.
-
(2012)
Facial Plast Surg Clin North Am
, vol.20
, pp. 87-91
-
-
Manes, R.P.1
Batra, P.S.2
-
94
-
-
84856377975
-
Bacterial pattern in chronic sinusitis and cystic fibrosis
-
Godoy, J.M., Godoy, A.N., Ribalta, G., Largo, I., Bacterial pattern in chronic sinusitis and cystic fibrosis. Otolaryngol Head Neck Surg 145 (2011), 673–676.
-
(2011)
Otolaryngol Head Neck Surg
, vol.145
, pp. 673-676
-
-
Godoy, J.M.1
Godoy, A.N.2
Ribalta, G.3
Largo, I.4
-
95
-
-
49849095285
-
Assessment of trends in antimicrobial resistance in chronic rhinosinusitis
-
Bhattacharyya, N., Kepnes, L.J., Assessment of trends in antimicrobial resistance in chronic rhinosinusitis. Ann Otol Rhinol Laryngol 117 (2008), 448–452.
-
(2008)
Ann Otol Rhinol Laryngol
, vol.117
, pp. 448-452
-
-
Bhattacharyya, N.1
Kepnes, L.J.2
-
96
-
-
4344592126
-
The microbiology and antimicrobial resistance patterns in chronic rhinosinusitis
-
Kingdom, T.T., Swain, R.E., The microbiology and antimicrobial resistance patterns in chronic rhinosinusitis. Am J Otolaryngol 25 (2004), 323–328.
-
(2004)
Am J Otolaryngol
, vol.25
, pp. 323-328
-
-
Kingdom, T.T.1
Swain, R.E.2
-
97
-
-
0022503120
-
Possible mechanisms of reduction of nasal mucociliary clearance in chronic sinusitis
-
Majima, Y., Sakakura, Y., Matsubara, T., Miyoshi, Y., Possible mechanisms of reduction of nasal mucociliary clearance in chronic sinusitis. Clin Otolaryngol Allied Sci 11 (1986), 55–60.
-
(1986)
Clin Otolaryngol Allied Sci
, vol.11
, pp. 55-60
-
-
Majima, Y.1
Sakakura, Y.2
Matsubara, T.3
Miyoshi, Y.4
-
98
-
-
0031855106
-
Human nasal ciliary-beat frequency in normal and chronic sinusitis subjects
-
Braverman, I., Wright, E.D., Wang, C.G., Eidelman, D., Frenkiel, S., Human nasal ciliary-beat frequency in normal and chronic sinusitis subjects. J Otolaryngol 27 (1998), 145–152.
-
(1998)
J Otolaryngol
, vol.27
, pp. 145-152
-
-
Braverman, I.1
Wright, E.D.2
Wang, C.G.3
Eidelman, D.4
Frenkiel, S.5
-
99
-
-
33746149026
-
Altered sinonasal ciliary dynamics in chronic rhinosinusitis
-
Chen, B., Shaari, J., Claire, S.E., et al. Altered sinonasal ciliary dynamics in chronic rhinosinusitis. Am J Rhinol 20 (2006), 325–329.
-
(2006)
Am J Rhinol
, vol.20
, pp. 325-329
-
-
Chen, B.1
Shaari, J.2
Claire, S.E.3
-
100
-
-
84980332255
-
Correlation of T2R38 taste phenotype and in vitro biofilm formation from nonpolypoid chronic rhinosinusitis patients
-
Adappa, N.D., Truesdale, C.M., Workman, A.D., et al. Correlation of T2R38 taste phenotype and in vitro biofilm formation from nonpolypoid chronic rhinosinusitis patients. Int Forum Allergy Rhinol 6 (2016), 783–791.
-
(2016)
Int Forum Allergy Rhinol
, vol.6
, pp. 783-791
-
-
Adappa, N.D.1
Truesdale, C.M.2
Workman, A.D.3
-
101
-
-
84891595945
-
The bitter taste receptor T2R38 is an independent risk factor for chronic rhinosinusitis requiring sinus surgery
-
Adappa, N.D., Zhang, Z., Palmer, J.N., et al. The bitter taste receptor T2R38 is an independent risk factor for chronic rhinosinusitis requiring sinus surgery. Int Forum Allergy Rhinol 4 (2014), 3–7.
-
(2014)
Int Forum Allergy Rhinol
, vol.4
, pp. 3-7
-
-
Adappa, N.D.1
Zhang, Z.2
Palmer, J.N.3
-
102
-
-
84875042411
-
Genetics of the taste receptor T2R38 correlates with chronic rhinosinusitis necessitating surgical intervention
-
Adappa, N.D., Howland, T.J., Palmer, J.N., et al. Genetics of the taste receptor T2R38 correlates with chronic rhinosinusitis necessitating surgical intervention. Int Forum Allergy Rhinol 3 (2013), 184–187.
-
(2013)
Int Forum Allergy Rhinol
, vol.3
, pp. 184-187
-
-
Adappa, N.D.1
Howland, T.J.2
Palmer, J.N.3
-
103
-
-
84953786087
-
TAS2R38 genotype predicts surgical outcome in nonpolypoid chronic rhinosinusitis
-
Adappa, N.D., Farquhar, D., Palmer, J.N., et al. TAS2R38 genotype predicts surgical outcome in nonpolypoid chronic rhinosinusitis. Int Forum Allergy Rhinol 6 (2016), 25–33.
-
(2016)
Int Forum Allergy Rhinol
, vol.6
, pp. 25-33
-
-
Adappa, N.D.1
Farquhar, D.2
Palmer, J.N.3
-
104
-
-
84991783869
-
TAS2R38 taste receptor gene and chronic rhinosinusitis: new data from an Italian population
-
Gallo, S., Grossi, S., Montrasio, G., et al. TAS2R38 taste receptor gene and chronic rhinosinusitis: new data from an Italian population. BMC Med Genet, 17, 2016, 54.
-
(2016)
BMC Med Genet
, vol.17
, pp. 54
-
-
Gallo, S.1
Grossi, S.2
Montrasio, G.3
-
105
-
-
84994681089
-
The correlation of TAS2R38 gene variants with higher risk for chronic rhinosinusitis in Polish patients
-
Dżaman, K., Zagor, M., Sarnowska, E., Krzeski, A., Kantor, I., The correlation of TAS2R38 gene variants with higher risk for chronic rhinosinusitis in Polish patients. Otolaryngol Pol 70 (2016), 13–18.
-
(2016)
Otolaryngol Pol
, vol.70
, pp. 13-18
-
-
Dżaman, K.1
Zagor, M.2
Sarnowska, E.3
Krzeski, A.4
Kantor, I.5
-
106
-
-
85019199184
-
The impact of bitter taste receptor genetics on culturable bacteria in chronic rhinosinusitis
-
Rom, D.I., Christensen, J.M., Alvarado, R., Sacks, R., Harvey, R.J., The impact of bitter taste receptor genetics on culturable bacteria in chronic rhinosinusitis. Rhinology 55 (2017), 90–94.
-
(2017)
Rhinology
, vol.55
, pp. 90-94
-
-
Rom, D.I.1
Christensen, J.M.2
Alvarado, R.3
Sacks, R.4
Harvey, R.J.5
-
107
-
-
84938505828
-
Tasting Pseudomonas aeruginosa biofilms: human neutrophils express the bitter receptor T2R38 as sensor for the quorum sensing molecule N-(3-oxododecanoyl)-L-homoserine lactone
-
Maurer, S., Wabnitz, G.H., Kahle, N.A., et al. Tasting Pseudomonas aeruginosa biofilms: human neutrophils express the bitter receptor T2R38 as sensor for the quorum sensing molecule N-(3-oxododecanoyl)-L-homoserine lactone. Front Immunol, 6, 2015, 369.
-
(2015)
Front Immunol
, vol.6
, pp. 369
-
-
Maurer, S.1
Wabnitz, G.H.2
Kahle, N.A.3
-
108
-
-
85012929713
-
Sensing developing biofilms: the bitter receptor T2R38 on myeloid cells
-
Gaida, M.M., Dapunt, U., Hänsch, G.M., Sensing developing biofilms: the bitter receptor T2R38 on myeloid cells. Pathog Dis, 74, 2016.
-
(2016)
Pathog Dis
, vol.74
-
-
Gaida, M.M.1
Dapunt, U.2
Hänsch, G.M.3
-
109
-
-
84895452125
-
Genetic variations in taste receptors are associated with chronic rhinosinusitis: a replication study
-
Mfuna, E.L., Filali-Mouhim, A., Boisvert, P., Boulet, L.P., Bossé Y., Desrosiers, M., Genetic variations in taste receptors are associated with chronic rhinosinusitis: a replication study. Int Forum Allergy Rhinol 4 (2014), 200–206.
-
(2014)
Int Forum Allergy Rhinol
, vol.4
, pp. 200-206
-
-
Mfuna, E.L.1
Filali-Mouhim, A.2
Boisvert, P.3
Boulet, L.P.4
Bossé, Y.5
Desrosiers, M.6
-
110
-
-
85031682535
-
Bitter and sweet taste tests are reflective of disease status in chronic rhinosinusitis
-
pii: S2213-2198(17)30739-0. [Epub ahead of print]
-
Workman, A.D., Brooks, S.G., Kohanski, M.A., et al. Bitter and sweet taste tests are reflective of disease status in chronic rhinosinusitis. J Allergy Clin Immunol Pract, 2017 Oct 17, 10.1016/j.jaip.2017.09.014 pii: S2213-2198(17)30739-0. [Epub ahead of print].
-
(2017)
J Allergy Clin Immunol Pract
-
-
Workman, A.D.1
Brooks, S.G.2
Kohanski, M.A.3
-
111
-
-
77649260272
-
Nasal chemosensory cells use bitter taste signaling to detect irritants and bacterial signals
-
Tizzano, M., Gulbransen, B.D., Vandenbeuch, A., et al. Nasal chemosensory cells use bitter taste signaling to detect irritants and bacterial signals. Proc Natl Acad Sci U S A 107 (2010), 3210–3215.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 3210-3215
-
-
Tizzano, M.1
Gulbransen, B.D.2
Vandenbeuch, A.3
-
112
-
-
84899050450
-
Cholinergic neurotransmission links solitary chemosensory cells to nasal inflammation
-
Saunders, C.J., Christensen, M., Finger, T.E., Tizzano, M., Cholinergic neurotransmission links solitary chemosensory cells to nasal inflammation. Proc Natl Acad Sci U S A 111 (2014), 6075–6080.
-
(2014)
Proc Natl Acad Sci U S A
, vol.111
, pp. 6075-6080
-
-
Saunders, C.J.1
Christensen, M.2
Finger, T.E.3
Tizzano, M.4
-
113
-
-
84907448696
-
Sinonasal solitary chemosensory cells “taste” the upper respiratory environment to regulate innate immunity
-
Lee, R.J., Cohen, N.A., Sinonasal solitary chemosensory cells “taste” the upper respiratory environment to regulate innate immunity. Am J Rhinol Allergy 28 (2014), 366–373.
-
(2014)
Am J Rhinol Allergy
, vol.28
, pp. 366-373
-
-
Lee, R.J.1
Cohen, N.A.2
-
114
-
-
84868513768
-
Sweet talk: insights into the nature and importance of glucose transport in lung epithelium
-
Garnett, J.P., Baker, E.H., Baines, D.L., Sweet talk: insights into the nature and importance of glucose transport in lung epithelium. Eur Respir J 40 (2012), 1269–1276.
-
(2012)
Eur Respir J
, vol.40
, pp. 1269-1276
-
-
Garnett, J.P.1
Baker, E.H.2
Baines, D.L.3
-
115
-
-
84922394858
-
Fructose transport-deficient Staphylococcus aureus reveals important role of epithelial glucose transporters in limiting sugar-driven bacterial growth in airway surface liquid
-
Garnett, J.P., Braun, D., McCarthy, A.J., et al. Fructose transport-deficient Staphylococcus aureus reveals important role of epithelial glucose transporters in limiting sugar-driven bacterial growth in airway surface liquid. Cell Mol Life Sci 71 (2014), 4665–4673.
-
(2014)
Cell Mol Life Sci
, vol.71
, pp. 4665-4673
-
-
Garnett, J.P.1
Braun, D.2
McCarthy, A.J.3
-
116
-
-
79251636742
-
Glucose depletion in the airway surface liquid is essential for sterility of the airways
-
Pezzulo, A.A., Gutiérrez, J., Duschner, K.S., et al. Glucose depletion in the airway surface liquid is essential for sterility of the airways. PLoS One, 6, 2011, e16166.
-
(2011)
PLoS One
, vol.6
, pp. e16166
-
-
Pezzulo, A.A.1
Gutiérrez, J.2
Duschner, K.S.3
-
117
-
-
34247867897
-
Hyperglycemia and cystic fibrosis alter respiratory fluid glucose concentrations estimated by breath condensate analysis
-
Baker, E.H., Clark, N., Brennan, A.L., et al. Hyperglycemia and cystic fibrosis alter respiratory fluid glucose concentrations estimated by breath condensate analysis. J Appl Physiol 2007:102 (1985), 1969–1975.
-
(1985)
J Appl Physiol
, vol.2007
, Issue.102
, pp. 1969-1975
-
-
Baker, E.H.1
Clark, N.2
Brennan, A.L.3
-
118
-
-
84930400569
-
Corticosteroid use does not alter nasal mucus glucose in chronic rhinosinusitis
-
Hatten, K.M., Palmer, J.N., Lee, R.J., Adappa, N.D., Kennedy, D.W., Cohen, N.A., Corticosteroid use does not alter nasal mucus glucose in chronic rhinosinusitis. Otolaryngol Head Neck Surg 152 (2015), 1140–1144.
-
(2015)
Otolaryngol Head Neck Surg
, vol.152
, pp. 1140-1144
-
-
Hatten, K.M.1
Palmer, J.N.2
Lee, R.J.3
Adappa, N.D.4
Kennedy, D.W.5
Cohen, N.A.6
-
119
-
-
17644389240
-
Lactisole interacts with the transmembrane domains of human T1R3 to inhibit sweet taste
-
Jiang, P., Cui, M., Zhao, B., et al. Lactisole interacts with the transmembrane domains of human T1R3 to inhibit sweet taste. J Biol Chem 280 (2005), 15238–15246.
-
(2005)
J Biol Chem
, vol.280
, pp. 15238-15246
-
-
Jiang, P.1
Cui, M.2
Zhao, B.3
-
120
-
-
84887948601
-
The taste of D- and L-amino acids: in vitro binding assays with cloned human bitter (TAS2Rs) and sweet (TAS1R2/TAS1R3) receptors
-
Bassoli, A., Borgonovo, G., Caremoli, F., Mancuso, G., The taste of D- and L-amino acids: in vitro binding assays with cloned human bitter (TAS2Rs) and sweet (TAS1R2/TAS1R3) receptors. Food Chem 150 (2014), 27–33.
-
(2014)
Food Chem
, vol.150
, pp. 27-33
-
-
Bassoli, A.1
Borgonovo, G.2
Caremoli, F.3
Mancuso, G.4
-
121
-
-
84903820663
-
Bacterial synthesis of D-amino acids
-
Radkov, A.D., Moe, L.A., Bacterial synthesis of D-amino acids. Appl Microbiol Biotechnol 98 (2014), 5363–5374.
-
(2014)
Appl Microbiol Biotechnol
, vol.98
, pp. 5363-5374
-
-
Radkov, A.D.1
Moe, L.A.2
-
122
-
-
18744369608
-
Genes and molecules involved in Aspergillus fumigatus virulence
-
Rementeria, A., López-Molina, N., Ludwig, A., et al. Genes and molecules involved in Aspergillus fumigatus virulence. Rev Iberoam Micol 22 (2005), 1–23.
-
(2005)
Rev Iberoam Micol
, vol.22
, pp. 1-23
-
-
Rementeria, A.1
López-Molina, N.2
Ludwig, A.3
-
123
-
-
84920646924
-
Mendelian genetics of human susceptibility to fungal infection
-
Lionakis, M.S., Netea, M.G., Holland, S.M., Mendelian genetics of human susceptibility to fungal infection. Cold Spring Harb Perspect Med, 4, 2014.
-
(2014)
Cold Spring Harb Perspect Med
, vol.4
-
-
Lionakis, M.S.1
Netea, M.G.2
Holland, S.M.3
-
124
-
-
84875736516
-
Genetics of chronic rhinosinusitis: state of the field and directions forward
-
993.e1–993.e5
-
Hsu, J., Avila, P.C., Kern, R.C., Hayes, M.G., Schleimer, R.P., Pinto, J.M., Genetics of chronic rhinosinusitis: state of the field and directions forward. J Allergy Clin Immunol 131 (2013), 977–993 993.e1–993.e5.
-
(2013)
J Allergy Clin Immunol
, vol.131
, pp. 977-993
-
-
Hsu, J.1
Avila, P.C.2
Kern, R.C.3
Hayes, M.G.4
Schleimer, R.P.5
Pinto, J.M.6
-
125
-
-
79953247858
-
Polymorphisms in the nitric oxide synthase 1 gene are associated with severe chronic rhinosinusitis
-
Zhang, Y., Endam, L.M., Filali-Mouhim, A., Bossé Y., Castano, R., Desrosiers, M., Polymorphisms in the nitric oxide synthase 1 gene are associated with severe chronic rhinosinusitis. Am J Rhinol Allergy 25 (2011), e49–e54.
-
(2011)
Am J Rhinol Allergy
, vol.25
, pp. e49-e54
-
-
Zhang, Y.1
Endam, L.M.2
Filali-Mouhim, A.3
Bossé, Y.4
Castano, R.5
Desrosiers, M.6
-
126
-
-
33645278974
-
Familial aggregation of sinonasal polyps correlates with severity of disease
-
Cohen, N.A., Widelitz, J.S., Chiu, A.G., Palmer, J.N., Kennedy, D.W., Familial aggregation of sinonasal polyps correlates with severity of disease. Otolaryngol Head Neck Surg 134 (2006), 601–604.
-
(2006)
Otolaryngol Head Neck Surg
, vol.134
, pp. 601-604
-
-
Cohen, N.A.1
Widelitz, J.S.2
Chiu, A.G.3
Palmer, J.N.4
Kennedy, D.W.5
-
127
-
-
85040741361
-
Bitter substances from plants used in traditional Chinese medicine exert biased activation of human bitter taste receptors
-
Behrens, M., Gu, M., Fan, S., Huang, C., Meyerhof, W., Bitter substances from plants used in traditional Chinese medicine exert biased activation of human bitter taste receptors. Chem Biol Drug Des 91 (2018), 422–433.
-
(2018)
Chem Biol Drug Des
, vol.91
, pp. 422-433
-
-
Behrens, M.1
Gu, M.2
Fan, S.3
Huang, C.4
Meyerhof, W.5
-
128
-
-
84877317364
-
Amino acid regulation of autophagy through the GPCR TAS1R1–TAS1R3
-
Wauson, E.M., Zaganjor, E., Cobb, M.H., Amino acid regulation of autophagy through the GPCR TAS1R1–TAS1R3. Autophagy 9 (2013), 418–419.
-
(2013)
Autophagy
, vol.9
, pp. 418-419
-
-
Wauson, E.M.1
Zaganjor, E.2
Cobb, M.H.3
-
129
-
-
84866846953
-
The G protein-coupled taste receptor T1R1/T1R3 regulates mTORC1 and autophagy
-
Wauson, E.M., Zaganjor, E., Lee, A.Y., et al. The G protein-coupled taste receptor T1R1/T1R3 regulates mTORC1 and autophagy. Mol Cell. 47 (2012), 851–862.
-
(2012)
Mol Cell.
, vol.47
, pp. 851-862
-
-
Wauson, E.M.1
Zaganjor, E.2
Lee, A.Y.3
-
130
-
-
84901849511
-
Role of nutrient-sensing taste 1 receptor (T1R) family members in gastrointestinal chemosensing
-
Shirazi-Beechey, S.P., Daly, K., Al-Rammahi, M., Moran, A.W., Bravo, D., Role of nutrient-sensing taste 1 receptor (T1R) family members in gastrointestinal chemosensing. Br J Nutr 111:suppl 1 (2014), S8–S15.
-
(2014)
Br J Nutr
, vol.111
, pp. S8-S15
-
-
Shirazi-Beechey, S.P.1
Daly, K.2
Al-Rammahi, M.3
Moran, A.W.4
Bravo, D.5
-
131
-
-
84859478593
-
G-protein-coupled receptors in intestinal chemosensation
-
Reimann, F., Tolhurst, G., Gribble, F.M., G-protein-coupled receptors in intestinal chemosensation. Cell Metab 15 (2012), 421–431.
-
(2012)
Cell Metab
, vol.15
, pp. 421-431
-
-
Reimann, F.1
Tolhurst, G.2
Gribble, F.M.3
-
132
-
-
79960786009
-
Gut bitter taste receptor signalling induces ABCB1 through a mechanism involving CCK
-
Jeon, T.I., Seo, Y.K., Osborne, T.F., Gut bitter taste receptor signalling induces ABCB1 through a mechanism involving CCK. Biochem J 438 (2011), 33–37.
-
(2011)
Biochem J
, vol.438
, pp. 33-37
-
-
Jeon, T.I.1
Seo, Y.K.2
Osborne, T.F.3
-
133
-
-
79960750572
-
The role of the gut sweet taste receptor in regulating GLP-1, PYY, and CCK release in humans
-
Gerspach, A.C., Steinert, R.E., Schönenberger, L., Graber-Maier, A., Beglinger, C., The role of the gut sweet taste receptor in regulating GLP-1, PYY, and CCK release in humans. Am J Physiol Endocrinol Metab 301 (2011), E317–E325.
-
(2011)
Am J Physiol Endocrinol Metab
, vol.301
, pp. E317-E325
-
-
Gerspach, A.C.1
Steinert, R.E.2
Schönenberger, L.3
Graber-Maier, A.4
Beglinger, C.5
-
134
-
-
42249094149
-
Taste cells of the gut and gastrointestinal chemosensation
-
Egan, J.M., Margolskee, R.F., Taste cells of the gut and gastrointestinal chemosensation. Mol Interv 8 (2008), 78–81.
-
(2008)
Mol Interv
, vol.8
, pp. 78-81
-
-
Egan, J.M.1
Margolskee, R.F.2
-
135
-
-
58049095069
-
Bitter taste receptors influence glucose homeostasis
-
Dotson, C.D., Zhang, L., Xu, H., et al. Bitter taste receptors influence glucose homeostasis. PLoS One, 3, 2008, e3974.
-
(2008)
PLoS One
, vol.3
, pp. e3974
-
-
Dotson, C.D.1
Zhang, L.2
Xu, H.3
-
136
-
-
35448986920
-
Gut-expressed gustducin and taste receptors regulate secretion of glucagon-like peptide-1
-
Jang, H.J., Kokrashvili, Z., Theodorakis, M.J., et al. Gut-expressed gustducin and taste receptors regulate secretion of glucagon-like peptide-1. Proc Natl Acad Sci U S A 104 (2007), 15069–15074.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 15069-15074
-
-
Jang, H.J.1
Kokrashvili, Z.2
Theodorakis, M.J.3
-
138
-
-
33751100128
-
Colocalization of the alpha-subunit of gustducin with PYY and GLP-1 in L cells of human colon
-
Rozengurt, N., Wu, S.V., Chen, M.C., Huang, C., Sternini, C., Rozengurt, E., Colocalization of the alpha-subunit of gustducin with PYY and GLP-1 in L cells of human colon. Am J Physiol Gastrointest Liver Physiol 291 (2006), G792–G802.
-
(2006)
Am J Physiol Gastrointest Liver Physiol
, vol.291
, pp. G792-G802
-
-
Rozengurt, N.1
Wu, S.V.2
Chen, M.C.3
Huang, C.4
Sternini, C.5
Rozengurt, E.6
-
139
-
-
85011923274
-
Taste and smell GPCRs in the lung: evidence for a previously unrecognized widespread chemosensory system
-
An, S.S., Liggett, S.B., Taste and smell GPCRs in the lung: evidence for a previously unrecognized widespread chemosensory system. Cell Signal 41 (2018), 82–88.
-
(2018)
Cell Signal
, vol.41
, pp. 82-88
-
-
An, S.S.1
Liggett, S.B.2
-
140
-
-
84898727600
-
Bitter taste receptor function in asthmatic and nonasthmatic human airway smooth muscle cells
-
Robinett, K.S., Koziol-White, C.J., Akoluk, A., An, S.S., Panettieri, R.A., Liggett, S.B., Bitter taste receptor function in asthmatic and nonasthmatic human airway smooth muscle cells. Am J Respir Cell Mol Biol 50 (2014), 678–683.
-
(2014)
Am J Respir Cell Mol Biol
, vol.50
, pp. 678-683
-
-
Robinett, K.S.1
Koziol-White, C.J.2
Akoluk, A.3
An, S.S.4
Panettieri, R.A.5
Liggett, S.B.6
-
141
-
-
84865126124
-
TAS2R activation promotes airway smooth muscle relaxation despite β(2)-adrenergic receptor tachyphylaxis
-
An, S.S., Wang, W.C., Koziol-White, C.J., et al. TAS2R activation promotes airway smooth muscle relaxation despite β(2)-adrenergic receptor tachyphylaxis. Am J Physiol Lung Cell Mol Physiol 303 (2012), L304–L311.
-
(2012)
Am J Physiol Lung Cell Mol Physiol
, vol.303
, pp. L304-L311
-
-
An, S.S.1
Wang, W.C.2
Koziol-White, C.J.3
-
142
-
-
78149355561
-
Bitter taste receptors on airway smooth muscle bronchodilate by localized calcium signaling and reverse obstruction
-
Deshpande, D.A., Wang, W.C., McIlmoyle, E.L., et al. Bitter taste receptors on airway smooth muscle bronchodilate by localized calcium signaling and reverse obstruction. Nat Med 16 (2010), 1299–1304.
-
(2010)
Nat Med
, vol.16
, pp. 1299-1304
-
-
Deshpande, D.A.1
Wang, W.C.2
McIlmoyle, E.L.3
-
143
-
-
79952138344
-
Bitter taste receptors and α-gustducin regulate the secretion of ghrelin with functional effects on food intake and gastric emptying
-
Janssen, S., Laermans, J., Verhulst, P.J., Thijs, T., Tack, J., Depoortere, I., Bitter taste receptors and α-gustducin regulate the secretion of ghrelin with functional effects on food intake and gastric emptying. Proc Natl Acad Sci U S A 108 (2011), 2094–2099.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 2094-2099
-
-
Janssen, S.1
Laermans, J.2
Verhulst, P.J.3
Thijs, T.4
Tack, J.5
Depoortere, I.6
-
144
-
-
70350352914
-
Epithelium, cilia, and mucus: their importance in chronic rhinosinusitis
-
Antunes, M.B., Gudis, D.A., Cohen, N.A., Epithelium, cilia, and mucus: their importance in chronic rhinosinusitis. Immunol Allergy Clin North Am 29 (2009), 631–643.
-
(2009)
Immunol Allergy Clin North Am
, vol.29
, pp. 631-643
-
-
Antunes, M.B.1
Gudis, D.A.2
Cohen, N.A.3
-
145
-
-
34247558990
-
Nitric oxide-dependent cilia regulatory enzyme localization in bovine bronchial epithelial cells
-
Stout, S.L., Wyatt, T.A., Adams, J.J., Sisson, J.H., Nitric oxide-dependent cilia regulatory enzyme localization in bovine bronchial epithelial cells. J Histochem Cytochem 55 (2007), 433–442.
-
(2007)
J Histochem Cytochem
, vol.55
, pp. 433-442
-
-
Stout, S.L.1
Wyatt, T.A.2
Adams, J.J.3
Sisson, J.H.4
|