Sweet taste receptor expressed in pancreatic β-cells activates the calcium and cyclic AMP signaling systems and stimulates insulin secretion

PLoS ONE

Volumn 4, Issue 4, 2009, Pages

  Nakagawa, Yuko ^a   Nagasawa, Masahiro ^a   Yamada, Satoko ^a   Hara, Akemi ^a   Mogami, Hideo ^b   Nikolaev, Viacheslav O ^c   Lohse, Martin J ^c   Shigemura, Noriatsu ^d   Ninomiya, Yuzo ^d   Kojima, Itaru ^a  

^a GUNMA UNIVERSITY   (Japan)

^b HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c UNIVERSITY OF WÜRZBURG   (Germany)

^d KYUSHU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINOETHOXYDIPHENYLBORANE; ACESULFAME; CALCIUM; CYCLIC AMP; FURA 2; G PROTEIN COUPLED RECEPTOR; GREEN FLUORESCENT PROTEIN; HETERODIMER; INSULIN; MESSENGER RNA; NIFEDIPINE; PROTEIN KINASE C; SACCHARIN; SUCRALOSE; SWEET TASTE RECEPTOR; SWEETENING AGENT; UNCLASSIFIED DRUG; DRUG DERIVATIVE; PRIMER DNA; SUCROSE; TRICHLOROSUCROSE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CELL LINE; CONTROLLED STUDY; CYTOPLASM; ENZYME ACTIVATION; EXTRACELLULAR CALCIUM; GENE EXPRESSION REGULATION; IMMUNOHISTOCHEMISTRY; INSULIN RELEASE; MALE; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RADIOIMMUNOASSAY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TASTE BUD; ANIMAL; METABOLISM; NUCLEOTIDE SEQUENCE; PANCREAS ISLET; SECRETION; TASTE;

ANIMALS; BASE SEQUENCE; CALCIUM; CELL LINE; CYCLIC AMP; CYTOPLASM; DNA PRIMERS; ENZYME ACTIVATION; INSULIN; ISLETS OF LANGERHANS; MICE; PROTEIN KINASE C; RECEPTORS, G-PROTEIN-COUPLED; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SUCROSE; TASTE;

EID: 65249129179     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0005106     Document Type: Article

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