Mouse nasal epithelial innate immune responses to Pseudomonas aeruginosa quorum-sensing molecules require taste signaling components

Innate Immunity

Volumn 20, Issue 6, 2014, Pages 606-617

  Lee, Robert J ^a   Chen, Bei ^a   Redding, Kevin M ^b   Margolskee, Robert F ^b   Cohen, Noam A ^a,b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Acyl homoserine lactone; Chronic rhinosinusitis; Innate immunity; Mucociliary clearance; Nitric oxide; T2R bitter taste receptor

Indexed keywords

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; EGTAZIC ACID; N ACYLHOMOSERINE LACTONE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; GAMMA BUTYROLACTONE DERIVATIVE; GUSTDUCIN; PHOSPHOLIPASE C BETA; PLCB2 PROTEIN, MOUSE; TRANSDUCIN; TRANSIENT RECEPTOR POTENTIAL CHANNEL M; TRPM5 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BACTERIUM CULTURE; CALCIUM SIGNALING; CELL MEMBRANE POTENTIAL; CILIATED EPITHELIUM; CONTROLLED STUDY; EPITHELIUM CELL; INNATE IMMUNITY; MOUSE; MUCOCILIARY CLEARANCE; MUCOCILIARY TRANSPORT; NONHUMAN; NOSE MUCOSA; POLYMERASE CHAIN REACTION; PSEUDOMONAS AERUGINOSA; QUORUM SENSING; SIGNAL TRANSDUCTION; TASTE BUD; BACTERIAL CLEARANCE; BITTER TASTE; CHRONIC RHINOSINUSITIS; GRAM NEGATIVE BACTERIUM; UPPER RESPIRATORY TRACT INFECTION; ANIMAL; CHEMISTRY; DRUG EFFECTS; GENETICS; IMMUNOLOGY; KNOCKOUT MOUSE; PHYSIOLOGY; TASTE;

ACYL-BUTYROLACTONES; ANIMALS; IMMUNITY, INNATE; MICE; MICE, KNOCKOUT; NASAL MUCOSA; NITRIC OXIDE; PHOSPHOLIPASE C BETA; PSEUDOMONAS AERUGINOSA; QUORUM SENSING; SIGNAL TRANSDUCTION; TASTE; TRANSDUCIN; TRPM CATION CHANNELS;

EID: 84907058830     PISSN: 17534259     EISSN: 17534267     Source Type: Journal    
DOI: 10.1177/1753425913503386     Document Type: Article

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