Bitter and sweet taste receptors regulate human upper respiratory innate immunity

Journal of Clinical Investigation

Volumn 124, Issue 3, 2014, Pages 1393-1405

  Lee, Robert J ^a   Kofonow, Jennifer M ^a   Rosen, Philip L ^a   Siebert, Adam P ^a   Chen, Bei ^a   Doghramji, Laurel ^a   Xiong, Guoxiang ^b   Adappa, Nithin D ^a   Palmer, James N ^a   Kennedy, David W ^a   Kreindler, James L ^b   Margolskee, Robert F ^c   Cohen, Noam A ^a,d  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^c MONELL CHEMICAL SENSES CENTER   (United States)

^d VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BITTER TASTE RECEPTOR; G PROTEIN COUPLED RECEPTOR; GLUCOSE; POLYPEPTIDE ANTIBIOTIC AGENT; SWEET TASTE RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BACTERIAL INFECTION; CALCIUM SIGNALING; CELL ACTIVATION; CHRONIC RHINOSINUSITIS; CONTROLLED STUDY; EPITHELIUM CELL; EXPLANT; GAP JUNCTION; GLUCOSE BLOOD LEVEL; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPERGLYCEMIA; INNATE IMMUNITY; MOUSE; NONHUMAN; NOSE SECRETION; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SURFACE PROPERTY; UPPER RESPIRATORY TRACT INFECTION;

CALCIUM SIGNALING; CELLS, CULTURED; CILIA; EPITHELIAL CELLS; GLUCOSE; HUMANS; IMMUNITY, INNATE; NASAL MUCOSA; PSEUDOMONAS AERUGINOSA; QUATERNARY AMMONIUM COMPOUNDS; RECEPTORS, G-PROTEIN-COUPLED; RHINITIS; SINUSITIS; TISSUE CULTURE TECHNIQUES;

EID: 84896770768     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI72094     Document Type: Article

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