Genetic loss or pharmacological blockade of testes-expressed taste genes causes male sterility

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 30, 2013, Pages 12319-12324

  Mosinger, Bedrich ^a   Redding, Kevin M ^a   Parker, M Rockwell ^a   Yevshayeva, Valeriya ^b   Yee, Karen K ^a   Dyomina, Katerina ^a   Li, Yan ^a   Margolskee, Robert F ^a  

^a MONELL CHEMICAL SENSES CENTER   (United States)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

Phenoxy compounds; Spermiogenesis

Indexed keywords

CLOFIBRATE; MESSENGER RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EPIDIDYMIS; EXPERIMENTAL MODEL; GENE; GENE ACTIVATION; GENE EXPRESSION; GENE INACTIVATION; GERM CELL; GNAT3 GENE; MALE; MALE INFERTILITY; MALE STERILITY; MOUSE; NONHUMAN; NULL ALLELE; PRIORITY JOURNAL; SEMEN ABNORMALITY; SIGNAL TRANSDUCTION; SPERMATID; SPERMATOGENESIS; SPERMATOZOON COUNT; SPERMATOZOON MOTILITY; TAS1R3 GENE; TESTIS; TRANSGENE;

PHENOXY COMPOUNDS; SPERMIOGENESIS;

ANIMALS; HUMANS; INFERTILITY, MALE; MALE; MICE; MICE, TRANSGENIC; MODELS, ANIMAL; RECEPTORS, G-PROTEIN-COUPLED; TASTE; TESTIS; TRANSDUCIN;

EID: 84880656949     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1302827110     Document Type: Article

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