-
1
-
-
0034443957
-
Heterogeneity of therapeutic responses in asthma
-
DOI 10.1258/0007142001903535
-
Drazen JM, Silverman EK, Lee TH. Heterogeneity of therapeutic responses in asthma. Br Med Bull 2000;56:1054-1070. (Pubitemid 32417168)
-
(2000)
British Medical Bulletin
, vol.56
, Issue.4
, pp. 1054-1070
-
-
Drazen, J.M.1
Silverman, E.K.2
Lee, T.H.3
-
2
-
-
0030907140
-
2-agonists. Is there cause for concern?
-
Lipworth BJ. Airway subsensitivity with long-acting beta 2-agonists: is there cause for concern? Drug Saf 1997;16:295-308. (Pubitemid 27268140)
-
(1997)
Drug Safety
, vol.16
, Issue.5
, pp. 295-308
-
-
Lipworth, B.J.1
-
3
-
-
0021930430
-
Changes in bronchial hyperreactivity induced by 4 weeks of treatment with antiasthmatic drugs in patients with allergic asthma: A comparison between budesonide and terbutaline
-
DOI 10.1016/0091-6749(85)90786-9
-
Kraan J, Koëter GH, vd Mark TW, Sluiter HJ, de Vries K. Changes in bronchial hyperreactivity induced by 4 weeks of treatment with antiasthmatic drugs in patients with allergic asthma: a comparison between budesonide and terbutaline. J Allergy Clin Immunol 1985;76:628-636. (Pubitemid 15245030)
-
(1985)
Journal of Allergy and Clinical Immunology
, vol.76
, Issue.4
, pp. 628-636
-
-
Kraan, J.1
Koeter, G.H.2
Van Der, M.T.3
-
4
-
-
0026786753
-
2-adrenoceptor agonist, salmeterol, on airway hyperresponsiveness in patients with mild asthma
-
2-adrenoceptor agonist, salmeterol, on airway hyperresponsiveness in patients with mild asthma. N Engl J Med 1992;327:1198-1203.
-
(1992)
N Engl J Med
, vol.327
, pp. 1198-1203
-
-
Cheung, D.1
Timmers, M.C.2
Zwinderman, A.H.3
Bel, E.H.4
Dijkman, J.H.5
Sterk, P.J.6
-
5
-
-
0032888402
-
Beta-agonists: What is the evidence that their use increases the risk of asthma morbidity and mortality?
-
DOI 10.1016/S0091-6749(99)70270-8
-
Beasley R, Pearce N, Crane J, Burgess C. Beta-agonists: what is the evidence that their use increases the risk of asthma morbidity and mortality? J Allergy Clin Immunol 1999;104:S18-S30. (Pubitemid 29426706)
-
(1999)
Journal of Allergy and Clinical Immunology
, vol.104
, Issue.2 II
-
-
Beasley, R.1
Pearce, N.2
Crane, J.3
Burgess, C.4
-
6
-
-
0028169718
-
The b2-agonist controversy: Observations, explanations and relationship to asthma epidemiology
-
Sears MR, Taylor DR. The b2-agonist controversy: observations, explanations and relationship to asthma epidemiology. Drug Saf 1994;11:259-283.
-
(1994)
Drug Saf
, vol.11
, pp. 259-283
-
-
Sears, M.R.1
Taylor, D.R.2
-
7
-
-
77950051793
-
Long-acting beta-agonists with and without inhaled corticosteroids and catastrophic asthma events
-
Salpeter SR, Wall AJ, Buckley NS. Long-acting beta-agonists with and without inhaled corticosteroids and catastrophic asthma events. Am J Med 2010;123:322-328, e2.
-
(2010)
Am J Med
, vol.123
-
-
Salpeter, S.R.1
Wall, A.J.2
Buckley, N.S.3
-
8
-
-
0033574195
-
Oral montelukast, inhaled beclomethasone, and placebo for chronic asthma: A randomized, controlled trial
-
Malmstrom K, Rodriguez-Gomez G, Guerra J, Villaran C, Piñeiro A, Wei LX, Seidenberg BC, Reiss TF; Montelukast/Beclomethasone Study Group. Oral montelukast, inhaled beclomethasone, and placebo for chronic asthma: a randomized, controlled trial. Ann Intern Med 1999;130:487-495. (Pubitemid 29135801)
-
(1999)
Annals of Internal Medicine
, vol.130
, Issue.6
, pp. 487-495
-
-
Malmstrom, K.1
Rodriguez-Gomez, G.2
Guerra, J.3
Villaran, C.4
Pineiro, A.5
Wei, L.X.6
Seidenberg, B.C.7
Reiss, T.F.8
-
9
-
-
84877865366
-
Bitter taste receptors on airway smooth muscle as targets for novel bronchodilators
-
Liggett SB. Bitter taste receptors on airway smooth muscle as targets for novel bronchodilators. Expert Opin Ther Targets 2013;17:721-731.
-
(2013)
Expert Opin Ther Targets
, vol.17
, pp. 721-731
-
-
Liggett, S.B.1
-
11
-
-
42449122192
-
Alternative splicing of the G protein-coupled receptor superfamily in human airway smooth muscle diversifies the complement of receptors
-
DOI 10.1073/pnas.0801319105
-
Einstein R, Jordan H, Zhou W, Brenner M, Moses EG, Liggett SB. Alternative splicing of the G protein-coupled receptor superfamily in human airway smooth muscle diversi fies the complement of receptors. Proc Natl Acad Sci USA 2008;105:5230-5235. (Pubitemid 351738539)
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.13
, pp. 5230-5235
-
-
Einstein, R.1
Jordan, H.2
Zhou, W.3
Brenner, M.4
Moses, E.G.5
Liggett, S.B.6
-
12
-
-
78149355561
-
Bitter taste receptors on airway smooth muscle bronchodilate by localized calcium signaling and reverse obstruction
-
Deshpande DA, Wang WCH, McIlmoyle EL, Robinett KS, Schillinger RM, An SS, Sham JSK, Liggett SB. Bitter taste receptors on airway smooth muscle bronchodilate by localized calcium signaling and reverse obstruction. Nat Med 2010;16:1299-1304.
-
(2010)
Nat Med
, vol.16
, pp. 1299-1304
-
-
Deshpande, D.A.1
Wang, W.C.H.2
McIlmoyle, E.L.3
Robinett, K.S.4
Schillinger, R.M.5
An, S.S.6
Sham, J.S.K.7
Liggett, S.B.8
-
13
-
-
84880170996
-
Transcriptome analysis reveals upregulation of bitter taste receptors in severe asthmatics
-
Orsmark-Pietras CO, James A, Konradsen JR, Nordlund B, Soderhall C, Pulkkinen V, Pedroletti C, Daham K, Kupczyk M, Dahlen B, et al. Transcriptome analysis reveals upregulation of bitter taste receptors in severe asthmatics. Eur Respir J 2012.
-
(2012)
Eur Respir J
-
-
Orsmark-Pietras, C.O.1
James, A.2
Konradsen, J.R.3
Nordlund, B.4
Soderhall, C.5
Pulkkinen, V.6
Pedroletti, C.7
Daham, K.8
Kupczyk, M.9
Dahlen, B.10
-
14
-
-
0022978869
-
In vitro responsiveness of human asthmatic bronchus to carbachol, histamine, b-adrenoceptor agonists and theophylline
-
Goldie RG, Spina D, Henry PJ, Lulich KM, Paterson JW. In vitro responsiveness of human asthmatic bronchus to carbachol, histamine, b-adrenoceptor agonists and theophylline. Br J Clin Pharmacol 1986;22:669-676. (Pubitemid 17199006)
-
(1986)
British Journal of Clinical Pharmacology
, vol.22
, Issue.6
, pp. 669-676
-
-
Goldie, R.G.1
Spina, D.2
Henry, P.J.3
-
15
-
-
48749118638
-
Dual ERK and phosphatidylinositol 3-kinase pathways control airway smooth muscle proliferation: Differences in asthma
-
Burgess JK, Lee JH, Ge Q, Ramsay EE, Poniris MH, Parmentier J, Roth M, Johnson PR, Hunt NH, Black JL, et al. Dual ERK and phosphatidylinositol 3-kinase pathways control airway smooth muscle proliferation: differences in asthma. J Cell Physiol 2008;216:673-679.
-
(2008)
J Cell Physiol
, vol.216
, pp. 673-679
-
-
Burgess, J.K.1
Lee, J.H.2
Ge, Q.3
Ramsay, E.E.4
Poniris, M.H.5
Parmentier, J.6
Roth, M.7
Johnson, P.R.8
Hunt, N.H.9
Black, J.L.10
-
16
-
-
34248175188
-
Histamine and tryptase modulate asthmatic airway smooth muscle GM-CSF and RANTES release
-
DOI 10.1183/09031936.00106306
-
Chhabra J, Li YZ, Alkhouri H, Blake AE, Ge Q, Armour CL, Hughes JM. Histamine and tryptase modulate asthmatic airway smooth muscle GM-CSF and RANTES release. Eur Respir J 2007;29:861-870. (Pubitemid 46711889)
-
(2007)
European Respiratory Journal
, vol.29
, Issue.5
, pp. 861-870
-
-
Chhabra, J.1
Li, Y.-Z.2
Alkhouri, H.3
Blake, A.E.4
Ge, Q.5
Armour, C.L.6
Hughes, J.M.7
-
17
-
-
37549041957
-
Bronchial smooth muscle remodeling involves calcium-dependent enhanced mitochondrial biogenesis in asthma
-
Trian T, Benard G, Begueret H, Rossignol R, Girodet PO, Ghosh D, Ousova O, Vernejoux JM, Marthan R, Tunon-de-Lara JM, et al. Bronchial smooth muscle remodeling involves calcium-dependent enhanced mitochondrial biogenesis in asthma. J Exp Med 2007;204:3173-3181.
-
(2007)
J Exp Med
, vol.204
, pp. 3173-3181
-
-
Trian, T.1
Benard, G.2
Begueret, H.3
Rossignol, R.4
Girodet, P.O.5
Ghosh, D.6
Ousova, O.7
Vernejoux, J.M.8
Marthan, R.9
Tunon-de-Lara, J.M.10
-
18
-
-
79956124769
-
β2-Agonist induced cAMP is decreased in asthmatic airway smooth muscle due to increased PDE4D
-
Trian T, Burgess JK, Niimi K, Moir LM, Ge Q, Berger P, Liggett SB, Black JL, Oliver BG. β2-Agonist induced cAMP is decreased in asthmatic airway smooth muscle due to increased PDE4D. PLoS ONE 2011;6:e20000.
-
(2011)
PLoS ONE
, vol.6
-
-
Trian, T.1
Burgess, J.K.2
Niimi, K.3
Moir, L.M.4
Ge, Q.5
Berger, P.6
Liggett, S.B.7
Black, J.L.8
Oliver, B.G.9
-
19
-
-
79954427461
-
TNF-a regulation of CD38 expression in human airway smooth muscle: Role of MAP kinases and NF-κB
-
Jude JA, Panettieri RA Jr, Walseth TF, Kannan MS. TNF-a regulation of CD38 expression in human airway smooth muscle: role of MAP kinases and NF-κB. Adv Exp Med Biol 2011;691:449-459.
-
(2011)
Adv Exp Med Biol
, vol.691
, pp. 449-459
-
-
Jude, J.A.1
Panettieri Jr., R.A.2
Walseth, T.F.3
Kannan, M.S.4
-
20
-
-
67649771753
-
Diminished sarco/endoplasmic reticulum Ca21 ATPase (SERCA) expression contributes to airway remodelling in bronchial asthma
-
Mahn K, Hirst SJ, Ying S, Holt MR, Lavender P, Ojo OO, Siew L, Simcock DE, McVicker CG, Kanabar V, et al. Diminished sarco/endoplasmic reticulum Ca21 ATPase (SERCA) expression contributes to airway remodelling in bronchial asthma. Proc Natl Acad Sci USA 2009;106:10775-10780.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 10775-10780
-
-
Mahn, K.1
Hirst, S.J.2
Ying, S.3
Holt, M.R.4
Lavender, P.5
Ojo, O.O.6
Siew, L.7
Simcock, D.E.8
McVicker, C.G.9
Kanabar, V.10
-
22
-
-
53049093560
-
Steroids completely reverse albuterol-induced beta(2)-adrenergic receptor tolerance in human small airways
-
Cooper PR, Panettieri RA Jr. Steroids completely reverse albuterol-induced beta(2)-adrenergic receptor tolerance in human small airways. J Allergy Clin Immunol 2008;122:734-740.
-
(2008)
J Allergy Clin Immunol
, vol.122
, pp. 734-740
-
-
Cooper, P.R.1
Panettieri Jr., R.A.2
-
23
-
-
80555156680
-
Agonistpromoted homologous desensitization of human airway smooth muscle bitter taste receptors
-
Robinett KS, Deshpande DA, Malone MM, Liggett SB. Agonistpromoted homologous desensitization of human airway smooth muscle bitter taste receptors. Am J Respir Cell Mol Biol 2011;45:1069-1074.
-
(2011)
Am J Respir Cell Mol Biol
, vol.45
, pp. 1069-1074
-
-
Robinett, K.S.1
Deshpande, D.A.2
Malone, M.M.3
Liggett, S.B.4
-
24
-
-
33745618476
-
Do biophysical properties of the airway smooth muscle in culture predict airway hyperresponsiveness?
-
DOI 10.1165/rcmb.2005-0453OC
-
An SS, Fabry B, Trepat X, Wang N, Fredberg JJ. Do biophysical properties of the airway smooth muscle in culture predict airway hyperresponsiveness? Am J Respir Cell Mol Biol 2006;35:55-64. (Pubitemid 43993154)
-
(2006)
American Journal of Respiratory Cell and Molecular Biology
, vol.35
, Issue.1
, pp. 55-64
-
-
An, S.S.1
Fabry, B.2
Trepat, X.3
Wang, N.4
Fredberg, J.J.5
-
25
-
-
0036720679
-
Stiffness changes in cultured airway smooth muscle cells
-
An SS, Laudadio RE, Lai J, Rogers RA, Fredberg JJ. Stiffness changes in cultured airway smooth muscle cells. Am J Physiol Cell Physiol 2002;283:C792-C801. (Pubitemid 34920312)
-
(2002)
American Journal of Physiology - Cell Physiology
, vol.283
, Issue.3
-
-
An, S.S.1
Laudadio, R.E.2
Lai, J.3
Rogers, R.A.4
Fredberg, J.J.5
-
27
-
-
33646386694
-
Airway smooth muscle prostaglandin-EP1 receptors directly modulate beta2-adrenergic receptors within a unique heterodimeric complex
-
McGraw DW, Mihlbachler KA, Schwarb MR, Rahman FF, Small KM, Almoosa KF, Liggett SB. Airway smooth muscle prostaglandin-EP1 receptors directly modulate beta2-adrenergic receptors within a unique heterodimeric complex. J Clin Invest 2006;116:1400-1409.
-
(2006)
J Clin Invest
, vol.116
, pp. 1400-1409
-
-
McGraw, D.W.1
Mihlbachler, K.A.2
Schwarb, M.R.3
Rahman, F.F.4
Small, K.M.5
Almoosa, K.F.6
Liggett, S.B.7
-
29
-
-
1642545168
-
IL-13 enhances agonist-evoked calcium signals and contractile responses in airway smooth muscle
-
DOI 10.1038/sj.bjp.0705558
-
Tliba O, Deshpande D, Chen H, Van Besien C, Kannan M, Panettieri RA Jr, Amrani Y. IL-13 enhances agonist-evoked calcium signals and contractile responses in airway smooth muscle. Br J Pharmacol 2003;140:1159-1162. (Pubitemid 38117418)
-
(2003)
British Journal of Pharmacology
, vol.140
, Issue.7
, pp. 1159-1162
-
-
Tliba, O.1
Deshpande, D.2
Chen, H.3
Van Besien, C.4
Kannan, M.5
Panettieri Jr., R.A.6
Amrani, Y.7
-
30
-
-
0037364452
-
CD38/cyclic ADP-ribose-mediated Ca21 signaling contributes to airway smooth muscle hyper-responsiveness
-
Deshpande DA, Walseth TF, Panettieri RA, Kannan MS. CD38/cyclic ADP-ribose-mediated Ca21 signaling contributes to airway smooth muscle hyper-responsiveness. FASEB J 2003;17:452-454.
-
(2003)
FASEB J
, vol.17
, pp. 452-454
-
-
Deshpande, D.A.1
Walseth, T.F.2
Panettieri, R.A.3
Kannan, M.S.4
-
31
-
-
68949108170
-
TLR3 activation stimulates cytokine secretion without altering agonist-induced human small airway contraction or relaxation
-
Cooper PR, Lamb R, Day ND, Branigan PJ, Kajekar R, San Mateo L, Hornby PJ, Panettieri RA Jr. TLR3 activation stimulates cytokine secretion without altering agonist-induced human small airway contraction or relaxation. Am J Physiol Lung Cell Mol Physiol 2009;297:L530-L537.
-
(2009)
Am J Physiol Lung Cell Mol Physiol
, vol.297
-
-
Cooper, P.R.1
Lamb, R.2
Day, N.D.3
Branigan, P.J.4
Kajekar, R.5
San Mateo, L.6
Hornby, P.J.7
Panettieri Jr., R.A.8
-
32
-
-
23444451466
-
CCR3 expression and function in asthmatic airway smooth muscle cells
-
Joubert P, Lajoie-Kadoch S, Labonté I, Gounni AS, Maghni K, Wellemans V, Chakir J, Laviolette M, Hamid Q, Lamkhioued B. CCR3 expression and function in asthmatic airway smooth muscle cells. J Immunol 2005;175:2702-2708. (Pubitemid 41113886)
-
(2005)
Journal of Immunology
, vol.175
, Issue.4
, pp. 2702-2708
-
-
Joubert, P.1
Lajoie-Kadoch, S.2
Labonte, I.3
Gounni, A.S.4
Maghni, K.5
Wellemans, V.6
Chakir, J.7
Laviolette, M.8
Hamid, Q.9
Lamkhioued, B.10
-
33
-
-
84870879028
-
The bitter taste receptor (TAS2R) agonists denatonium and chloroquine display distinct patterns of relaxation of the guinea pig trachea
-
Pulkkinen V, Manson ML, Säfholm J, Adner M, Dahlén SE. The bitter taste receptor (TAS2R) agonists denatonium and chloroquine display distinct patterns of relaxation of the guinea pig trachea. Am J Physiol Lung Cell Mol Physiol 2012;303:L956-L966.
-
(2012)
Am J Physiol Lung Cell Mol Physiol
, vol.303
-
-
Pulkkinen, V.1
Manson, M.L.2
Säfholm, J.3
Adner, M.4
Dahlén, S.E.5
|