The bitter pill: Clinical drugs that activate the human bitter taste receptor TAS2R14

FASEB Journal

Volumn 28, Issue 3, 2014, Pages 1181-1197

  Levit, Anat ^a   Nowak, Stefanie ^b   Peters, Maximilian ^a   Wiener, Ayana ^a   Meyerhof, Wolfgang ^b   Behrens, Maik ^b   Niv, Masha Y ^a  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^b GERMAN INSTITUTE OF HUMAN NUTRITION   (Germany)

Author keywords

Cross reactivity; Drug repositioning; GPCRs; Multispecificity

Indexed keywords

BITTER TASTE RECEPTOR; G PROTEIN COUPLED RECEPTOR; LIGAND; POTASSIUM CHANNEL HERG; UNCLASSIFIED DRUG; TASTE RECEPTORS, TYPE 2;

AGONIST; ARTICLE; BITTER TASTE; DRUG REPOSITIONING; HEK293 CELL LINE; IN VITRO STUDY; LIPOPHILICITY; PHARMACOPHORE; PHYSICAL CHEMISTRY; PILL; PRIORITY JOURNAL; TASTE BUD; TRANSIENT TRANSFECTION; BIOLOGICAL MODEL; CELL STRAIN HEK293; CROSS-REACTIVITY; DRUG POTENTIATION; GPCRS; HUMAN; MULTISPECIFICITY; STRUCTURE ACTIVITY RELATION;

CROSS-REACTIVITY; DRUG REPOSITIONING; GPCRS; MULTISPECIFICITY;

HEK293 CELLS; HUMANS; MODELS, BIOLOGICAL; RECEPTORS, G-PROTEIN-COUPLED; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84899503308     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.13-242594     Document Type: Article

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