Nasal chemosensory cells use bitter taste signaling to detect irritants and bacterial signals

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 7, 2010, Pages 3210-3215

  Tizzano, Marco ^a,b   Gulbransen, Brian D ^a,b   Vandenbeuch, Aurelie ^a,b,c   Clapp, Tod R ^a,c   Herman, Jake P ^a   Sibhatu, Hiruy M ^a   Churchill, Mair E A ^a   Silver, Wayne L ^d   Kinnamon, Sue C ^a,b,c   Finger, Thomas E ^a,b  

^a UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF COLORADO   (United States)

^c Department of Environmental and Radiological Health Sciences   (United States)

^d WAKE FOREST UNIVERSITY   (United States)

Author keywords

Gustducin; Olfactory; Quorum sensing; Respiration; Trigeminal

Indexed keywords

GREEN FLUORESCENT PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN; N ACYLHOMOSERINE LACTONE; PROTEIN G ALPHA GASTDUCIN; PROTEIN T2R; TRANSIENT RECEPTOR POTENTIAL CHANNEL 5; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BITTER TASTE; CALCIUM CELL LEVEL; CELL ISOLATION; GRAM NEGATIVE BACTERIUM; MOUSE; NONHUMAN; PRIORITY JOURNAL; QUORUM SENSING; RESPIRATORY EPITHELIUM; SENSORY NERVE CELL; SENSORY STIMULATION;

ANIMALS; CALCIUM; CHEMORECEPTOR CELLS; FLUORESCENCE; GENE DELETION; GRAM-NEGATIVE BACTERIA; HETEROTRIMERIC GTP-BINDING PROTEINS; IMMUNOHISTOCHEMISTRY; MICE; MICE, TRANSGENIC; NASAL MUCOSA; QUATERNARY AMMONIUM COMPOUNDS; RECEPTORS, G-PROTEIN-COUPLED; TASTE; TRIGEMINAL NERVE; TRPM CATION CHANNELS;

BACTERIA (MICROORGANISMS); MENTHA; NEGIBACTERIA;

EID: 77649260272     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0911934107     Document Type: Article

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