Intestinal epithelial tuft cells initiate type 2 mucosal immunity to helminth parasites

Nature

Volumn 529, Issue 7585, 2016, Pages 226-230

  Gerbe, François ^a,b   Sidot, Emmanuelle ^a,b   Smyth, Danielle J ^c,f   Ohmoto, Makoto ^d   Matsumoto, Ichiro ^d   Dardalhon, Valérie ^b,e   Cesses, Pierre ^a,b   Garnier, Laure ^a,b   Pouzolles, Marie ^b,e   Brulin, Bénédicte ^a,b   Bruschi, Marco ^a,b   Harcus, Yvonne ^c   Zimmermann, Valérie S ^b,e   Taylor, Naomi ^b,e   Maizels, Rick M ^c,f   Jay, Philippe ^a,b  

^a INSTITUT DE GÉNOMIQUE FONCTIONNELLE   (France)

^b UNIV MONTPELLIER   (France)

^c UNIVERSITY OF EDINBURGH   (United Kingdom)

^d MONELL CHEMICAL SENSES CENTER   (United States)

^e CNRS   (France)

^f UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 13; INTERLEUKIN 25; INTERLEUKIN 4; INTERLEUKIN 4 RECEPTOR ALPHA; POU DOMAIN CLASS 2 TRANSCRIPTION FACTOR 3; PROTEIN; RESISTIN; RESISTIN LIKE BETA; UNCLASSIFIED DRUG; INTERLEUKIN 17; INTERLEUKIN 4 RECEPTOR; OCTAMER TRANSCRIPTION FACTOR; POU2F3 PROTEIN, MOUSE;

CELLS AND CELL COMPONENTS; DEFENSE MECHANISM; GENE EXPRESSION; GLOBAL PERSPECTIVE; HOST-PARASITE INTERACTION; IMMUNITY; INFECTIVITY; MUCUS; NEMATODE; PARASITE; PROTEIN; PUBLIC HEALTH; RODENT;

ADAPTIVE IMMUNITY; ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELL EXPANSION; CELL HYPERPLASIA; CELL LINEAGE; CONTROLLED STUDY; CYTOKINE RELEASE; ENTEROENDOCRINE CELL; EPITHELIAL TUFT CELL; EPITHELIUM CELL; GENE EXPRESSION; GOBLET CELL; HELIGMOSOMOIDES POLYGYRUS; HELMINTH; HELMINTHIASIS; IMMUNOCOMPETENT CELL; INTESTINE CELL; INTESTINE EPITHELIUM; MOUSE; MUCOSAL IMMUNITY; MUCUS; NONHUMAN; PANETH CELL; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STEM CELL; TYPE 2 MUCOSAL IMMUNITY; WILD TYPE; WORM EXPULSION; ANIMAL; CELL PROLIFERATION; CYTOLOGY; DEFICIENCY; FEEDBACK SYSTEM; FEMALE; IMMUNOLOGY; INTESTINE MUCOSA; MALE; METABOLISM; NIPPOSTRONGYLUS; PARASITE; STRONGYLE INFECTION; TH2 CELL;

MUS; NIPPOSTRONGYLUS BRASILIENSIS; VERMES;

ANIMALS; CELL LINEAGE; CELL PROLIFERATION; FEEDBACK, PHYSIOLOGICAL; FEMALE; GOBLET CELLS; IMMUNITY, MUCOSAL; INTERLEUKIN-13; INTERLEUKIN-17; INTESTINAL MUCOSA; MALE; MICE; NIPPOSTRONGYLUS; OCTAMER TRANSCRIPTION FACTORS; PARASITES; RECEPTORS, INTERLEUKIN-4; SIGNAL TRANSDUCTION; STEM CELLS; STRONGYLIDA INFECTIONS; TH2 CELLS;

EID: 84954561117     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature16527     Document Type: Article

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