메뉴 건너뛰기




Volumn 17, Issue 11, 2017, Pages

T Cell Receptor Profiling in Type 1 Diabetes

Author keywords

Adaptive immunity; Autoimmunity; Human immune repertoire; Immunosequencing; T cell receptor; Type 1 diabetes

Indexed keywords

BIOLOGICAL MARKER; CHIMERIC ANTIGEN RECEPTOR; EPITOPE; HLA ANTIGEN; RIBOSOME PROTEIN; T LYMPHOCYTE RECEPTOR; LYMPHOCYTE ANTIGEN RECEPTOR;

EID: 85031429533     PISSN: 15344827     EISSN: 15390829     Source Type: Journal    
DOI: 10.1007/s11892-017-0946-4     Document Type: Review
Times cited : (29)

References (266)
  • 1
    • 27144475336 scopus 로고    scopus 로고
    • Type 1 diabetes genes and pathways shared by humans and NOD mice
    • COI: 1:CAS:528:DC%2BD2MXht1Ghs73O, PID: 16257508
    • Wicker LS, Clark J, Fraser HI, Garner VE, Gonzalez-Munoz A, Healy B, et al. Type 1 diabetes genes and pathways shared by humans and NOD mice. J Autoimmun. 2005;25(Suppl):29–33. https://doi.org/10.1016/j.jaut.2005.09.009.
    • (2005) J Autoimmun , vol.25 , pp. 29-33
    • Wicker, L.S.1    Clark, J.2    Fraser, H.I.3    Garner, V.E.4    Gonzalez-Munoz, A.5    Healy, B.6
  • 2
    • 36549038975 scopus 로고    scopus 로고
    • Animal models of spontaneous autoimmune disease: type 1 diabetes in the nonobese diabetic mouse
    • COI: 1:CAS:528:DC%2BD2sXot1agu74%3D, PID: 17876100
    • Giarratana N, Penna G, Adorini L. Animal models of spontaneous autoimmune disease: type 1 diabetes in the nonobese diabetic mouse. Methods Mol Biol. 2007;380:285–311. https://doi.org/10.1007/978-1-59745-395-0_17.
    • (2007) Methods Mol Biol , vol.380 , pp. 285-311
    • Giarratana, N.1    Penna, G.2    Adorini, L.3
  • 3
    • 84876724327 scopus 로고    scopus 로고
    • Type 1 diabetes: primary antigen/peptide/register/trimolecular complex
    • COI: 1:CAS:528:DC%2BC3sXoslOmtA%3D%3D, PID: 22956469
    • Sosinowski T, Eisenbarth GS. Type 1 diabetes: primary antigen/peptide/register/trimolecular complex. Immunol Res. 2013;55(1–3):270–6. https://doi.org/10.1007/s12026-012-8367-6.
    • (2013) Immunol Res , vol.55 , Issue.1-3 , pp. 270-276
    • Sosinowski, T.1    Eisenbarth, G.S.2
  • 4
    • 84999837765 scopus 로고    scopus 로고
    • Immune and pancreatic beta cell interactions in type 1 diabetes
    • COI: 1:CAS:528:DC%2BC28XhsVOqtbbJ, PID: 27659143
    • Boldison J, Wong FS. Immune and pancreatic beta cell interactions in type 1 diabetes. Trends Endocrinol Metab. 2016;27(12):856–67. https://doi.org/10.1016/j.tem.2016.08.007.
    • (2016) Trends Endocrinol Metab , vol.27 , Issue.12 , pp. 856-867
    • Boldison, J.1    Wong, F.S.2
  • 5
    • 0027468997 scopus 로고
    • Adoptive transfer of diabetes into immunodeficient NOD-scid/scid mice. Relative contributions of CD4+ and CD8+ T-cells from diabetic versus prediabetic NOD.NON-Thy-1a donors
    • COI: 1:STN:280:DyaK3s7jtFSrsA%3D%3D, PID: 8093606
    • Christianson SW, Shultz LD, Leiter EH. Adoptive transfer of diabetes into immunodeficient NOD-scid/scid mice. Relative contributions of CD4+ and CD8+ T-cells from diabetic versus prediabetic NOD.NON-Thy-1a donors. Diabetes. 1993;42(1):44–55.
    • (1993) Diabetes , vol.42 , Issue.1 , pp. 44-55
    • Christianson, S.W.1    Shultz, L.D.2    Leiter, E.H.3
  • 6
    • 0344338626 scopus 로고
    • Prevention of type I diabetes in nonobese diabetic mice by allogenic bone marrow transplantation
    • COI: 1:STN:280:DyaL28%2Fmsl2rsA%3D%3D, PID: 3906651
    • Ikehara S, Ohtsuki H, Good RA, Asamoto H, Nakamura T, Sekita K, et al. Prevention of type I diabetes in nonobese diabetic mice by allogenic bone marrow transplantation. Proc Natl Acad Sci U S A. 1985;82(22):7743–7.
    • (1985) Proc Natl Acad Sci U S A , vol.82 , Issue.22 , pp. 7743-7747
    • Ikehara, S.1    Ohtsuki, H.2    Good, R.A.3    Asamoto, H.4    Nakamura, T.5    Sekita, K.6
  • 7
    • 0027309516 scopus 로고
    • Transfer of insulin-dependent diabetes between HLA-identical siblings by bone marrow transplantation
    • COI: 1:STN:280:DyaK3s3mtFSrtQ%3D%3D, PID: 8098394
    • Lampeter EF, Homberg M, Quabeck K, Schaefer UW, Wernet P, Bertrams J, et al. Transfer of insulin-dependent diabetes between HLA-identical siblings by bone marrow transplantation. Lancet. 1993;341(8855):1243–4.
    • (1993) Lancet , vol.341 , Issue.8855 , pp. 1243-1244
    • Lampeter, E.F.1    Homberg, M.2    Quabeck, K.3    Schaefer, U.W.4    Wernet, P.5    Bertrams, J.6
  • 8
    • 0032554326 scopus 로고    scopus 로고
    • Transfer of diabetes type 1 by bone-marrow transplantation
    • COI: 1:STN:280:DyaK1c7ltlOhtQ%3D%3D, PID: 9492780
    • Lampeter EF, McCann SR, Kolb H. Transfer of diabetes type 1 by bone-marrow transplantation. Lancet. 1998;351(9102):568–9. https://doi.org/10.1016/s0140-6736(05)78555-x.
    • (1998) Lancet , vol.351 , Issue.9102 , pp. 568-569
    • Lampeter, E.F.1    McCann, S.R.2    Kolb, H.3
  • 10
    • 84962422694 scopus 로고    scopus 로고
    • Insulitis and beta-cell mass in the natural history of type 1 diabetes
    • COI: 1:CAS:528:DC%2BC28XhtVKltLfM, PID: 26581594
    • Campbell-Thompson M, Fu A, Kaddis JS, Wasserfall C, Schatz DA, Pugliese A, et al. Insulitis and beta-cell mass in the natural history of type 1 diabetes. Diabetes. 2016;65(3):719–31. https://doi.org/10.2337/db15-0779.
    • (2016) Diabetes , vol.65 , Issue.3 , pp. 719-731
    • Campbell-Thompson, M.1    Fu, A.2    Kaddis, J.S.3    Wasserfall, C.4    Schatz, D.A.5    Pugliese, A.6
  • 11
    • 84926299378 scopus 로고    scopus 로고
    • Rodent versus human insulitis: why the huge disconnect?
    • in't Veld P. Rodent versus human insulitis: why the huge disconnect? Curr Opin Endocrinol Diabetes Obes. 2015;22(2):86–90. https://doi.org/10.1097/med.0000000000000135.
    • (2015) Curr Opin Endocrinol Diabetes Obes. , vol.22 , Issue.2 , pp. 86-90
    • in't Veld, P.1
  • 12
    • 79960088916 scopus 로고    scopus 로고
    • Insulitis in human type 1 diabetes: the quest for an elusive lesion
    • In't Veld P. Insulitis in human type 1 diabetes: the quest for an elusive lesion. Islets. 2011;3(4):131–8.
    • (2011) Islets , vol.3 , Issue.4 , pp. 131-138
    • In't Veld, P.1
  • 13
    • 84924022501 scopus 로고    scopus 로고
    • Beta cell death and dysfunction during type 1 diabetes development in at-risk individuals
    • PID: 25642774
    • Herold KC, Usmani-Brown S, Ghazi T, Lebastchi J, Beam CA, Bellin MD, et al. Beta cell death and dysfunction during type 1 diabetes development in at-risk individuals. J Clin Invest. 2015;125(3):1163–73. https://doi.org/10.1172/jci78142.
    • (2015) J Clin Invest , vol.125 , Issue.3 , pp. 1163-1173
    • Herold, K.C.1    Usmani-Brown, S.2    Ghazi, T.3    Lebastchi, J.4    Beam, C.A.5    Bellin, M.D.6
  • 14
    • 79959386535 scopus 로고    scopus 로고
    • How does type 1 diabetes develop?: the notion of homicide or beta-cell suicide revisited
    • COI: 1:CAS:528:DC%2BC3MXmsVKltb4%3D, PID: 21525508
    • Atkinson MA, Bluestone JA, Eisenbarth GS, Hebrok M, Herold KC, Accili D, et al. How does type 1 diabetes develop?: the notion of homicide or beta-cell suicide revisited. Diabetes. 2011;60(5):1370–9. https://doi.org/10.2337/db10-1797.
    • (2011) Diabetes , vol.60 , Issue.5 , pp. 1370-1379
    • Atkinson, M.A.1    Bluestone, J.A.2    Eisenbarth, G.S.3    Hebrok, M.4    Herold, K.C.5    Accili, D.6
  • 15
    • 70350534475 scopus 로고    scopus 로고
    • Validity and reproducibility of measurement of islet autoreactivity by T-cell assays in subjects with early type 1 diabetes
    • COI: 1:CAS:528:DC%2BD1MXhsVCht77L, PID: 19675135
    • Herold KC, Brooks-Worrell B, Palmer J, Dosch HM, Peakman M, Gottlieb P, et al. Validity and reproducibility of measurement of islet autoreactivity by T-cell assays in subjects with early type 1 diabetes. Diabetes. 2009;58(11):2588–95. https://doi.org/10.2337/db09-0249.
    • (2009) Diabetes , vol.58 , Issue.11 , pp. 2588-2595
    • Herold, K.C.1    Brooks-Worrell, B.2    Palmer, J.3    Dosch, H.M.4    Peakman, M.5    Gottlieb, P.6
  • 16
    • 84908632192 scopus 로고    scopus 로고
    • Blood and islet phenotypes indicate immunological heterogeneity in type 1 diabetes
    • COI: 1:CAS:528:DC%2BC2cXhvVygsr7J, PID: 24939426
    • Arif S, Leete P, Nguyen V, Marks K, Nor NM, Estorninho M, et al. Blood and islet phenotypes indicate immunological heterogeneity in type 1 diabetes. Diabetes. 2014;63(11):3835–45. https://doi.org/10.2337/db14-0365.
    • (2014) Diabetes , vol.63 , Issue.11 , pp. 3835-3845
    • Arif, S.1    Leete, P.2    Nguyen, V.3    Marks, K.4    Nor, N.M.5    Estorninho, M.6
  • 17
    • 0032880017 scopus 로고    scopus 로고
    • Autoreactive T cell responses in insulin-dependent (type 1) diabetes mellitus. Report of the first international workshop for standardization of T cell assays
    • COI: 1:STN:280:DyaK1MvhtVamuw%3D%3D, PID: 10479395
    • Roep BO, Atkinson MA, van Endert PM, Gottlieb PA, Wilson SB, Sachs JA. Autoreactive T cell responses in insulin-dependent (type 1) diabetes mellitus. Report of the first international workshop for standardization of T cell assays. J Autoimmun. 1999;13(2):267–82. https://doi.org/10.1006/jaut.1999.0312 S0896-8411(99)90312-8.
    • (1999) J Autoimmun , vol.13 , Issue.2 , pp. 267-282
    • Roep, B.O.1    Atkinson, M.A.2    van Endert, P.M.3    Gottlieb, P.A.4    Wilson, S.B.5    Sachs, J.A.6
  • 18
    • 80855147987 scopus 로고    scopus 로고
    • Immunology of diabetes society T-cell workshop: HLA class I tetramer-directed epitope validation initiative T-cell workshop report-HLA class I tetramer validation initiative
    • COI: 1:CAS:528:DC%2BC3MXhs1Gqs73E, PID: 22069251
    • Mallone R, Scotto M, Janicki CN, James EA, Fitzgerald-Miller L, Wagner R, et al. Immunology of diabetes society T-cell workshop: HLA class I tetramer-directed epitope validation initiative T-cell workshop report-HLA class I tetramer validation initiative. Diabetes Metab Res Rev. 2011;27(8):720–6. https://doi.org/10.1002/dmrr.1243.
    • (2011) Diabetes Metab Res Rev , vol.27 , Issue.8 , pp. 720-726
    • Mallone, R.1    Scotto, M.2    Janicki, C.N.3    James, E.A.4    Fitzgerald-Miller, L.5    Wagner, R.6
  • 19
    • 78649358914 scopus 로고    scopus 로고
    • Current approaches to measuring human islet-antigen specific T cell function in type 1 diabetes
    • COI: 1:CAS:528:DC%2BC3cXhsFeqtbjN, PID: 20846160
    • Mannering SI, Wong FS, Durinovic-Belló I, Brooks-Worrell B, Tree TI, Cilio CM, et al. Current approaches to measuring human islet-antigen specific T cell function in type 1 diabetes. Clin Exp Immunol. 2010;162(2):197–209. https://doi.org/10.1111/j.1365-2249.2010.04237.x.
    • (2010) Clin Exp Immunol , vol.162 , Issue.2 , pp. 197-209
    • Mannering, S.I.1    Wong, F.S.2    Durinovic-Belló, I.3    Brooks-Worrell, B.4    Tree, T.I.5    Cilio, C.M.6
  • 20
    • 84910105185 scopus 로고    scopus 로고
    • Spatial map of human T cell compartmentalization and maintenance over decades of life
    • COI: 1:CAS:528:DC%2BC2cXhvV2msrnE, PID: 25417158
    • Thome J, Yudanin N, Ohmura Y, Kubota M, Grinshpun B, Sathaliyawala T, et al. Spatial map of human T cell compartmentalization and maintenance over decades of life. Cell. 2014;159(4):814–28.
    • (2014) Cell , vol.159 , Issue.4 , pp. 814-828
    • Thome, J.1    Yudanin, N.2    Ohmura, Y.3    Kubota, M.4    Grinshpun, B.5    Sathaliyawala, T.6
  • 21
    • 84893710050 scopus 로고    scopus 로고
    • Human memory T cells: generation, compartmentalization and homeostasis
    • COI: 1:CAS:528:DC%2BC3sXhvFart7rF
    • Farber D, Yudanin N, Restifo N. Human memory T cells: generation, compartmentalization and homeostasis. Nature Rev Immunol. 2014;14(1):24–35.
    • (2014) Nature Rev Immunol , vol.14 , Issue.1 , pp. 24-35
    • Farber, D.1    Yudanin, N.2    Restifo, N.3
  • 22
    • 73349085255 scopus 로고    scopus 로고
    • Beta cell-specific CD4+ T cell clonotypes in peripheral blood and the pancreatic islets are distinct
    • COI: 1:CAS:528:DC%2BD1MXhsVehtrjL
    • Li L, He Q, Garland A, Yi Z, Aybar LT, Kepler TB, et al. Beta cell-specific CD4+ T cell clonotypes in peripheral blood and the pancreatic islets are distinct. J Immunol (Baltimore, Md: 1950). 2009;183(11):7585–91. https://doi.org/10.4049/jimmunol.0901587.
    • (2009) J Immunol (Baltimore, Md: 1950) , vol.183 , Issue.11 , pp. 7585-7591
    • Li, L.1    He, Q.2    Garland, A.3    Yi, Z.4    Aybar, L.T.5    Kepler, T.B.6
  • 23
    • 84924610426 scopus 로고    scopus 로고
    • High diversity in the TCR repertoire of GAD65 autoantigen-specific human CD4+ T cells
    • COI: 1:CAS:528:DC%2BC2MXjvFShtrw%3D, This paper represents a comprehensive list of GAD65-reactive TCRs isolated by tetramer staining and then characterized via immuequencing
    • • Eugster A, Lindner A, Catani M, Heninger AK, Dahl A, Klemroth S, et al. High diversity in the TCR repertoire of GAD65 autoantigen-specific human CD4+ T cells. J of Immunol (Baltimore, Md: 1950). 2015;194(6):2531–8. https://doi.org/10.4049/jimmunol.1403031. This paper represents a comprehensive list of GAD65-reactive TCRs isolated by tetramer staining and then characterized via immunosequencing.
    • (2015) J of Immunol (Baltimore, Md: 1950) , vol.194 , Issue.6 , pp. 2531-2538
    • Eugster, A.1    Lindner, A.2    Catani, M.3    Heninger, A.K.4    Dahl, A.5    Klemroth, S.6
  • 24
    • 85015392227 scopus 로고    scopus 로고
    • CD8+ T cells specific for the islet autoantigen IGRP are restricted in their T cell receptor chain usage
    • PID: 28300170
    • Fuchs YF, Eugster A, Dietz S, Sebelefsky C, Kuhn D, Wilhelm C, et al. CD8+ T cells specific for the islet autoantigen IGRP are restricted in their T cell receptor chain usage. Sci Rep. 2017;7:44661. https://doi.org/10.1038/srep44661.
    • (2017) Sci Rep , vol.7 , pp. 44661
    • Fuchs, Y.F.1    Eugster, A.2    Dietz, S.3    Sebelefsky, C.4    Kuhn, D.5    Wilhelm, C.6
  • 25
    • 84962052827 scopus 로고    scopus 로고
    • Beta-cell-specific CD8 T cell phenotype in type 1 diabetes reflects chronic autoantigen exposure
    • COI: 1:CAS:528:DC%2BC2MXjvFanurs%3D, PID: 25249579
    • Skowera A, Ladell K, McLaren JE, Dolton G, Matthews KK, Gostick E, et al. Beta-cell-specific CD8 T cell phenotype in type 1 diabetes reflects chronic autoantigen exposure. Diabetes. 2015;64(3):916–25. https://doi.org/10.2337/db14-0332.
    • (2015) Diabetes , vol.64 , Issue.3 , pp. 916-925
    • Skowera, A.1    Ladell, K.2    McLaren, J.E.3    Dolton, G.4    Matthews, K.K.5    Gostick, E.6
  • 26
    • 42449144715 scopus 로고    scopus 로고
    • HLA DR-DQ haplotypes and genotypes and type 1 diabetes risk: analysis of the type 1 diabetes genetics consortium families
    • COI: 1:CAS:528:DC%2BD1cXksVGrsr4%3D, PID: 18252895
    • Erlich H, Valdes AM, Noble J, Carlson JA, Varney M, Concannon P, et al. HLA DR-DQ haplotypes and genotypes and type 1 diabetes risk: analysis of the type 1 diabetes genetics consortium families. Diabetes. 2008;57(4):1084–92. https://doi.org/10.2337/db07-1331.
    • (2008) Diabetes , vol.57 , Issue.4 , pp. 1084-1092
    • Erlich, H.1    Valdes, A.M.2    Noble, J.3    Carlson, J.A.4    Varney, M.5    Concannon, P.6
  • 27
    • 84885957703 scopus 로고    scopus 로고
    • Breakdown in peripheral tolerance in type 1 diabetes in mice and humans
    • PID: 22393537
    • Jeker LT, Bour-Jordan H, Bluestone JA. Breakdown in peripheral tolerance in type 1 diabetes in mice and humans. Cold Spring Harb Perspect Med. 2012;2(3):a007807. https://doi.org/10.1101/cshperspect.a007807.
    • (2012) Cold Spring Harb Perspect Med. , vol.2 , Issue.3 , pp. a007807
    • Jeker, L.T.1    Bour-Jordan, H.2    Bluestone, J.A.3
  • 28
    • 84937517806 scopus 로고    scopus 로고
    • Non-HLA gene effects on the disease process of type 1 diabetes: from HLA susceptibility to overt disease
    • COI: 1:CAS:528:DC%2BC2MXhtVegs7rP, PID: 26074154
    • Lempainen J, Laine AP, Hammais A, Toppari J, Simell O, Veijola R, et al. Non-HLA gene effects on the disease process of type 1 diabetes: from HLA susceptibility to overt disease. J Autoimmun. 2015;61:45–53. https://doi.org/10.1016/j.jaut.2015.05.005.
    • (2015) J Autoimmun , vol.61 , pp. 45-53
    • Lempainen, J.1    Laine, A.P.2    Hammais, A.3    Toppari, J.4    Simell, O.5    Veijola, R.6
  • 29
    • 80755135395 scopus 로고    scopus 로고
    • Genetics of the HLA region in the prediction of type 1 diabetes
    • COI: 1:CAS:528:DC%2BC3MXhsVeltLzL
    • Noble JA, Valdes AM. Genetics of the HLA region in the prediction of type 1 diabetes. Curr Diabetes Rep. 2011;11(6):533–42. https://doi.org/10.1007/s11892-011-0223-x.
    • (2011) Curr Diabetes Rep , vol.11 , Issue.6 , pp. 533-542
    • Noble, J.A.1    Valdes, A.M.2
  • 30
    • 0037386232 scopus 로고    scopus 로고
    • HLA-DPB1*0401 is associated with dominant protection against type 1 diabetes in the general Saudi population and in subjects with a high-risk DR/DQ haplotype
    • COI: 1:CAS:528:DC%2BD3sXjtlKgsLk%3D, PID: 12648278
    • Al-Hussein KA, Rama NR, Ahmad M, Rozemuller E, Tilanus MG. HLA-DPB1*0401 is associated with dominant protection against type 1 diabetes in the general Saudi population and in subjects with a high-risk DR/DQ haplotype. Eur J Immunogenet. 2003;30(2):115–9.
    • (2003) Eur J Immunogenet , vol.30 , Issue.2 , pp. 115-119
    • Al-Hussein, K.A.1    Rama, N.R.2    Ahmad, M.3    Rozemuller, E.4    Tilanus, M.G.5
  • 31
    • 84937797996 scopus 로고    scopus 로고
    • A run on the biobank: what have we learned about type 1 diabetes from the nPOD tissue repository?
    • COI: 1:CAS:528:DC%2BC2MXhtV2isLvM, PID: 26087339
    • Kaddis JS, Pugliese A, Atkinson MA. A run on the biobank: what have we learned about type 1 diabetes from the nPOD tissue repository? Curr Opin Endocrinol Diabetes Obes. 2015;22(4):290–5. https://doi.org/10.1097/med.0000000000000171.
    • (2015) Curr Opin Endocrinol Diabetes Obes , vol.22 , Issue.4 , pp. 290-295
    • Kaddis, J.S.1    Pugliese, A.2    Atkinson, M.A.3
  • 33
    • 58149299735 scopus 로고    scopus 로고
    • Analysis of islet inflammation in human type 1 diabetes
    • COI: 1:STN:280:DC%2BD1M%2FlslKltw%3D%3D, PID: 19128359
    • Willcox A, Richardson SJ, Bone AJ, Foulis AK, Morgan NG. Analysis of islet inflammation in human type 1 diabetes. Clin Exp Immunol. 2009;155(2):173–81. https://doi.org/10.1111/j.1365-2249.2008.03860.x.
    • (2009) Clin Exp Immunol , vol.155 , Issue.2 , pp. 173-181
    • Willcox, A.1    Richardson, S.J.2    Bone, A.J.3    Foulis, A.K.4    Morgan, N.G.5
  • 34
    • 84856825977 scopus 로고    scopus 로고
    • Demonstration of islet-autoreactive CD8 T cells in insulitic lesions from recent onset and long-term type 1 diabetes patients
    • COI: 1:CAS:528:DC%2BC38XhtFSqurk%3D, PID: 22213807
    • Coppieters KT, Dotta F, Amirian N, Campbell PD, Kay TW, Atkinson MA, et al. Demonstration of islet-autoreactive CD8 T cells in insulitic lesions from recent onset and long-term type 1 diabetes patients. J Exp Med. 2012;209(1):51–60. https://doi.org/10.1084/jem.20111187.
    • (2012) J Exp Med , vol.209 , Issue.1 , pp. 51-60
    • Coppieters, K.T.1    Dotta, F.2    Amirian, N.3    Campbell, P.D.4    Kay, T.W.5    Atkinson, M.A.6
  • 35
    • 32044467144 scopus 로고    scopus 로고
    • B cells are crucial for determinant spreading of T cell autoimmunity among beta cell antigens in diabetes-prone nonobese diabetic mice
    • COI: 1:CAS:528:DC%2BD28XpvFSjtQ%3D%3D, PID: 16456028
    • Tian J, Zekzer D, Lu Y, Dang H, Kaufman DL. B cells are crucial for determinant spreading of T cell autoimmunity among beta cell antigens in diabetes-prone nonobese diabetic mice. J Immunol. 2006;176(4):2654–61.
    • (2006) J Immunol , vol.176 , Issue.4 , pp. 2654-2661
    • Tian, J.1    Zekzer, D.2    Lu, Y.3    Dang, H.4    Kaufman, D.L.5
  • 36
    • 84946554983 scopus 로고    scopus 로고
    • Lessons from pancreas transplantation in type 1 diabetes: recurrence of islet autoimmunity
    • PID: 26547222, This paper provides longitudinal descriptions of autoreactive T cell clones appearing in conjunciton with autoantibodies in patients with recurring type 1 diabetes after pancreas transplant
    • • Burke GW 3rd, Vendrame F, Virdi SK, Ciancio G, Chen L, Ruiz P, et al. Lessons from pancreas transplantation in type 1 diabetes: recurrence of islet autoimmunity. Curr Diab Rep. 2015;15(12):121. https://doi.org/10.1007/s11892-015-0691-5. This paper provides longitudinal descriptions of autoreactive T cell clones appearing in conjunciton with autoantibodies in patients with recurring type 1 diabetes after pancreas transplant.
    • (2015) Curr Diab Rep , vol.15 , Issue.12 , pp. 121
    • Burke, G.W.1    Vendrame, F.2    Virdi, S.K.3    Ciancio, G.4    Chen, L.5    Ruiz, P.6
  • 37
    • 84862302663 scopus 로고    scopus 로고
    • Antigen targets of type 1 diabetes autoimmunity
    • PID: 22474615
    • Roep BO, Peakman M. Antigen targets of type 1 diabetes autoimmunity. Cold Spring Harb Perspect Med. 2012;2(4):a007781. https://doi.org/10.1101/cshperspect.a007781.
    • (2012) Cold Spring Harb Perspect Med. , vol.2 , Issue.4 , pp. a007781
    • Roep, B.O.1    Peakman, M.2
  • 38
    • 85055601298 scopus 로고    scopus 로고
    • Tissue distribution and clonal diversity of the T and B cell repertoire in type 1 diabetes
    • PID: 27942583, This paper represents the first report characterizing the adaptive immune repertoire in multiple organs and tissues isolated from type 1 diabetes versus control organ donors
    • • Seay HR, Yusko E, Rothweiler SJ, Zhang L, Posgai AL, Campbell-Thompson M, et al. Tissue distribution and clonal diversity of the T and B cell repertoire in type 1 diabetes. JCI Insight. 2016;1(20):e88242. https://doi.org/10.1172/jci.insight.88242. This paper represents the first report characterizing the adaptive immune repertoire in multiple organs and tissues isolated from type 1 diabetes versus control organ donors.
    • (2016) JCI Insight , vol.1 , Issue.20
    • Seay, H.R.1    Yusko, E.2    Rothweiler, S.J.3    Zhang, L.4    Posgai, A.L.5    Campbell-Thompson, M.6
  • 39
    • 80755153651 scopus 로고    scopus 로고
    • Discovery of low-affinity preproinsulin epitopes and detection of autoreactive CD8 T-cells using combinatorial MHC multimers
    • COI: 1:CAS:528:DC%2BC3MXhsVOltL%2FP, PID: 21636247
    • Unger WW, Velthuis J, Abreu JR, Laban S, Quinten E, Kester MG, et al. Discovery of low-affinity preproinsulin epitopes and detection of autoreactive CD8 T-cells using combinatorial MHC multimers. J Autoimmun. 2011;37(3):151–9. https://doi.org/10.1016/j.jaut.2011.05.012.
    • (2011) J Autoimmun , vol.37 , Issue.3 , pp. 151-159
    • Unger, W.W.1    Velthuis, J.2    Abreu, J.R.3    Laban, S.4    Quinten, E.5    Kester, M.G.6
  • 41
    • 0036312395 scopus 로고    scopus 로고
    • Detection of GAD65-specific T-cells by major histocompatibility complex class II tetramers in type 1 diabetic patients and at-risk subjects
    • COI: 1:CAS:528:DC%2BD38XjtlGmt70%3D, PID: 11978633
    • Reijonen H, Novak EJ, Kochik S, Heninger A, Liu AW, Kwok WW, et al. Detection of GAD65-specific T-cells by major histocompatibility complex class II tetramers in type 1 diabetic patients and at-risk subjects. Diabetes. 2002;51(5):1375–82. https://doi.org/10.2337/diabetes.51.5.1375.
    • (2002) Diabetes , vol.51 , Issue.5 , pp. 1375-1382
    • Reijonen, H.1    Novak, E.J.2    Kochik, S.3    Heninger, A.4    Liu, A.W.5    Kwok, W.W.6
  • 42
    • 33847338541 scopus 로고    scopus 로고
    • CD8+ T-cell responses identify beta-cell autoimmunity in human type 1 diabetes
    • COI: 1:CAS:528:DC%2BD2sXis12itrk%3D, PID: 17327428
    • Mallone R, Martinuzzi E, Blancou P, Novelli G, Afonso G, Dolz M, et al. CD8+ T-cell responses identify beta-cell autoimmunity in human type 1 diabetes. Diabetes. 2007;56(3):613–21. https://doi.org/10.2337/db06-1419.
    • (2007) Diabetes , vol.56 , Issue.3 , pp. 613-621
    • Mallone, R.1    Martinuzzi, E.2    Blancou, P.3    Novelli, G.4    Afonso, G.5    Dolz, M.6
  • 43
    • 84903993800 scopus 로고    scopus 로고
    • Linking T-cell receptor sequence to functional phenotype at the single-cell level
    • COI: 1:CAS:528:DC%2BC2cXhtVais7rI, PID: 24952902
    • Han A, Glanville J, Hansmann L, Davis MM. Linking T-cell receptor sequence to functional phenotype at the single-cell level. Nat Biotechnol. 2014;32(7):684–92. https://doi.org/10.1038/nbt.2938.
    • (2014) Nat Biotechnol , vol.32 , Issue.7 , pp. 684-692
    • Han, A.1    Glanville, J.2    Hansmann, L.3    Davis, M.M.4
  • 44
    • 3242768392 scopus 로고    scopus 로고
    • GAD65-specific CD4+ T-cells with high antigen avidity are prevalent in peripheral blood of patients with type 1 diabetes
    • COI: 1:CAS:528:DC%2BD2cXmtFGqsbo%3D, PID: 15277377
    • Reijonen H, Mallone R, Heninger AK, Laughlin EM, Kochik SA, Falk B, et al. GAD65-specific CD4+ T-cells with high antigen avidity are prevalent in peripheral blood of patients with type 1 diabetes. Diabetes. 2004;53(8):1987–94.
    • (2004) Diabetes , vol.53 , Issue.8 , pp. 1987-1994
    • Reijonen, H.1    Mallone, R.2    Heninger, A.K.3    Laughlin, E.M.4    Kochik, S.A.5    Falk, B.6
  • 45
    • 68949125346 scopus 로고    scopus 로고
    • Restricted autoantigen recognition associated with deletional and adaptive regulatory mechanisms
    • COI: 1:CAS:528:DC%2BD1MXnsVOqsLk%3D
    • Gebe JA, Yue BB, Unrath KA, Falk BA, Nepom GT. Restricted autoantigen recognition associated with deletional and adaptive regulatory mechanisms. J Immunol (Baltimore, Md: 1950). 2009;183(1):59–65. https://doi.org/10.4049/jimmunol.0804046.
    • (2009) J Immunol (Baltimore, Md: 1950) , vol.183 , Issue.1 , pp. 59-65
    • Gebe, J.A.1    Yue, B.B.2    Unrath, K.A.3    Falk, B.A.4    Nepom, G.T.5
  • 46
    • 79953189382 scopus 로고    scopus 로고
    • TCR bias of in vivo expanded T cells in pancreatic islets and spleen at the onset in human type 1 diabetes
    • COI: 1:CAS:528:DC%2BC3MXivVSjt70%3D
    • Codina-Busqueta E, Scholz E, Munoz-Torres PM, Roura-Mir C, Costa M, Xufre C, et al. TCR bias of in vivo expanded T cells in pancreatic islets and spleen at the onset in human type 1 diabetes. J Immunol (Baltimore, Md: 1950). 2011;186(6):3787–97. https://doi.org/10.4049/jimmunol.1002423.
    • (2011) J Immunol (Baltimore, Md: 1950) , vol.186 , Issue.6 , pp. 3787-3797
    • Codina-Busqueta, E.1    Scholz, E.2    Munoz-Torres, P.M.3    Roura-Mir, C.4    Costa, M.5    Xufre, C.6
  • 47
    • 84964987484 scopus 로고    scopus 로고
    • High-throughput sequencing reveals restricted TCR Vbeta usage and public TCRbeta clonotypes among pancreatic lymph node memory CD4(+) T cells and their involvement in autoimmune diabetes
    • COI: 1:CAS:528:DC%2BC28XnsV2ktr8%3D, PID: 27161799
    • Marrero I, Aguilera C, Hamm DE, Quinn A, Kumar V. High-throughput sequencing reveals restricted TCR Vbeta usage and public TCRbeta clonotypes among pancreatic lymph node memory CD4(+) T cells and their involvement in autoimmune diabetes. Mol Immunol. 2016;74:82–95. https://doi.org/10.1016/j.molimm.2016.04.013.
    • (2016) Mol Immunol , vol.74 , pp. 82-95
    • Marrero, I.1    Aguilera, C.2    Hamm, D.E.3    Quinn, A.4    Kumar, V.5
  • 48
    • 84860917533 scopus 로고    scopus 로고
    • Inflamed target tissue provides a specific niche for highly expanded T-cell clones in early human autoimmune disease
    • COI: 1:CAS:528:DC%2BC38XpvVSgsLs%3D, PID: 22294635
    • Klarenbeek PL, de Hair MJ, Doorenspleet ME, van Schaik BD, Esveldt RE, van de Sande MG, et al. Inflamed target tissue provides a specific niche for highly expanded T-cell clones in early human autoimmune disease. Ann Rheum Dis. 2012;71(6):1088–93. https://doi.org/10.1136/annrheumdis-2011-200612.
    • (2012) Ann Rheum Dis , vol.71 , Issue.6 , pp. 1088-1093
    • Klarenbeek, P.L.1    de Hair, M.J.2    Doorenspleet, M.E.3    van Schaik, B.D.4    Esveldt, R.E.5    van de Sande, M.G.6
  • 49
    • 84929643506 scopus 로고    scopus 로고
    • CD8+ TCR bias and immunodominance in HIV-1 infection
    • COI: 1:CAS:528:DC%2BC2MXotl2gsbo%3D, PID: 25911754
    • Kloverpris HN, McGregor R, McLaren JE, Ladell K, Harndahl M, Stryhn A, et al. CD8+ TCR bias and immunodominance in HIV-1 infection. J Immunol. 2015;194(11):5329–45. https://doi.org/10.4049/jimmunol.1400854.
    • (2015) J Immunol , vol.194 , Issue.11 , pp. 5329-5345
    • Kloverpris, H.N.1    McGregor, R.2    McLaren, J.E.3    Ladell, K.4    Harndahl, M.5    Stryhn, A.6
  • 50
    • 77954100566 scopus 로고    scopus 로고
    • Fine structural variations of alphabetaTCRs selected by vaccination with natural versus altered self-antigen in melanoma patients
    • COI: 1:CAS:528:DC%2BD1MXht1WhsbbF, PID: 19786555
    • Wieckowski S, Baumgaertner P, Corthesy P, Voelter V, Romero P, Speiser DE, et al. Fine structural variations of alphabetaTCRs selected by vaccination with natural versus altered self-antigen in melanoma patients. J Immunol. 2009;183(8):5397–406. https://doi.org/10.4049/jimmunol.0901460.
    • (2009) J Immunol , vol.183 , Issue.8 , pp. 5397-5406
    • Wieckowski, S.1    Baumgaertner, P.2    Corthesy, P.3    Voelter, V.4    Romero, P.5    Speiser, D.E.6
  • 51
    • 84928532251 scopus 로고    scopus 로고
    • Association of CD8(+) T lymphocyte repertoire spreading with the severity of DRESS syndrome
    • COI: 1:CAS:528:DC%2BC2MXhtFOrsrfM, PID: 25905582
    • Niu J, Jia Q, Ni Q, Yang Y, Chen G, Yang X, et al. Association of CD8(+) T lymphocyte repertoire spreading with the severity of DRESS syndrome. Sci Rep. 2015;5:9913. https://doi.org/10.1038/srep09913.
    • (2015) Sci Rep , vol.5 , pp. 9913
    • Niu, J.1    Jia, Q.2    Ni, Q.3    Yang, Y.4    Chen, G.5    Yang, X.6
  • 52
    • 84945466038 scopus 로고    scopus 로고
    • Paired TCRalphabeta analysis of virus-specific CD8(+) T cells exposes diversity in a previously defined ‘narrow’ repertoire
    • COI: 1:CAS:528:DC%2BC2MXotVeqsbg%3D, PID: 25804828
    • Cukalac T, Kan WT, Dash P, Guan J, Quinn KM, Gras S, et al. Paired TCRalphabeta analysis of virus-specific CD8(+) T cells exposes diversity in a previously defined ‘narrow’ repertoire. Immunol Cell Biol. 2015;93(9):804–14. https://doi.org/10.1038/icb.2015.44.
    • (2015) Immunol Cell Biol , vol.93 , Issue.9 , pp. 804-814
    • Cukalac, T.1    Kan, W.T.2    Dash, P.3    Guan, J.4    Quinn, K.M.5    Gras, S.6
  • 53
    • 84897386168 scopus 로고    scopus 로고
    • In vitro expansion of antigen-specific CD8(+) T cells distorts the T-cell repertoire
    • COI: 1:CAS:528:DC%2BC2cXivFCitL0%3D, PID: 24512815
    • Koning D, Costa AI, Hasrat R, Grady BP, Spijkers S, Nanlohy N, et al. In vitro expansion of antigen-specific CD8(+) T cells distorts the T-cell repertoire. J Immunol Methods. 2014;405:199–203. https://doi.org/10.1016/j.jim.2014.01.013.
    • (2014) J Immunol Methods , vol.405 , pp. 199-203
    • Koning, D.1    Costa, A.I.2    Hasrat, R.3    Grady, B.P.4    Spijkers, S.5    Nanlohy, N.6
  • 54
    • 79959536852 scopus 로고    scopus 로고
    • Large TCR diversity of virus-specific CD8 T cells provides the mechanistic basis for massive TCR renewal after antigen exposure
    • COI: 1:CAS:528:DC%2BC3MXntVGnurg%3D, PID: 21555537
    • Miconnet I, Marrau A, Farina A, Taffe P, Vigano S, Harari A, et al. Large TCR diversity of virus-specific CD8 T cells provides the mechanistic basis for massive TCR renewal after antigen exposure. J Immunol. 2011;186(12):7039–49. https://doi.org/10.4049/jimmunol.1003309.
    • (2011) J Immunol , vol.186 , Issue.12 , pp. 7039-7049
    • Miconnet, I.1    Marrau, A.2    Farina, A.3    Taffe, P.4    Vigano, S.5    Harari, A.6
  • 55
    • 84919433921 scopus 로고    scopus 로고
    • Clonal evolution of CD8+ T cell responses against latent viruses: relationship among phenotype, localization, and function
    • PID: 25339770
    • Remmerswaal EB, Klarenbeek PL, Alves NL, Doorenspleet ME, van Schaik BD, Esveldt RE, et al. Clonal evolution of CD8+ T cell responses against latent viruses: relationship among phenotype, localization, and function. J Virol. 2015;89(1):568–80. https://doi.org/10.1128/jvi.02003-14.
    • (2015) J Virol , vol.89 , Issue.1 , pp. 568-580
    • Remmerswaal, E.B.1    Klarenbeek, P.L.2    Alves, N.L.3    Doorenspleet, M.E.4    van Schaik, B.D.5    Esveldt, R.E.6
  • 56
    • 84991065403 scopus 로고    scopus 로고
    • Characterization of the T-cell receptor beta chain repertoire in tumor-infiltrating lymphocytes
    • COI: 1:CAS:528:DC%2BC28XhsFOktb3E, PID: 27465739
    • Nakanishi K, Kukita Y, Segawa H, Inoue N, Ohue M, Kato K. Characterization of the T-cell receptor beta chain repertoire in tumor-infiltrating lymphocytes. Cancer Med. 2016;5(9):2513–21. https://doi.org/10.1002/cam4.828.
    • (2016) Cancer Med , vol.5 , Issue.9 , pp. 2513-2521
    • Nakanishi, K.1    Kukita, Y.2    Segawa, H.3    Inoue, N.4    Ohue, M.5    Kato, K.6
  • 57
    • 18744385526 scopus 로고    scopus 로고
    • Expanded T cells from pancreatic lymph nodes of type 1 diabetic subjects recognize an insulin epitope
    • COI: 1:CAS:528:DC%2BD2MXktVWhtb0%3D, PID: 15889096
    • Kent SC, Chen Y, Bregoli L, Clemmings SM, Kenyon NS, Ricordi C, et al. Expanded T cells from pancreatic lymph nodes of type 1 diabetic subjects recognize an insulin epitope. Nature. 2005;435(7039):224–8. https://doi.org/10.1038/nature03625.
    • (2005) Nature , vol.435 , Issue.7039 , pp. 224-228
    • Kent, S.C.1    Chen, Y.2    Bregoli, L.3    Clemmings, S.M.4    Kenyon, N.S.5    Ricordi, C.6
  • 58
    • 84925428013 scopus 로고    scopus 로고
    • Narrowing of human influenza A virus-specific T cell receptor alpha and beta repertoires with increasing age
    • COI: 1:CAS:528:DC%2BC2MXlvVWlur8%3D, PID: 25609818
    • Gil A, Yassai MB, Naumov YN, Selin LK. Narrowing of human influenza A virus-specific T cell receptor alpha and beta repertoires with increasing age. J Virol. 2015;89(8):4102–16. https://doi.org/10.1128/jvi.03020-14.
    • (2015) J Virol , vol.89 , Issue.8 , pp. 4102-4116
    • Gil, A.1    Yassai, M.B.2    Naumov, Y.N.3    Selin, L.K.4
  • 59
    • 79959565627 scopus 로고    scopus 로고
    • Dominant clonotypes within HIV-specific T cell responses are programmed death-1high and CD127low and display reduced variant cross-reactivity
    • COI: 1:CAS:528:DC%2BC3MXntVGntLc%3D, PID: 21562156
    • Conrad JA, Ramalingam RK, Smith RM, Barnett L, Lorey SL, Wei J, et al. Dominant clonotypes within HIV-specific T cell responses are programmed death-1high and CD127low and display reduced variant cross-reactivity. J Immunol. 2011;186(12):6871–85. https://doi.org/10.4049/jimmunol.1004234.
    • (2011) J Immunol , vol.186 , Issue.12 , pp. 6871-6885
    • Conrad, J.A.1    Ramalingam, R.K.2    Smith, R.M.3    Barnett, L.4    Lorey, S.L.5    Wei, J.6
  • 60
    • 84949570628 scopus 로고    scopus 로고
    • Expanded CD8 T-cell sharing between periphery and CNS in multiple sclerosis
    • COI: 1:CAS:528:DC%2BC2MXhtVajurjN, PID: 26125037
    • Salou M, Garcia A, Michel L, Gainche-Salmon A, Loussouarn D, Nicol B, et al. Expanded CD8 T-cell sharing between periphery and CNS in multiple sclerosis. Ann Clin Transl Neurol. 2015;2(6):609–22. https://doi.org/10.1002/acn3.199.
    • (2015) Ann Clin Transl Neurol , vol.2 , Issue.6 , pp. 609-622
    • Salou, M.1    Garcia, A.2    Michel, L.3    Gainche-Salmon, A.4    Loussouarn, D.5    Nicol, B.6
  • 61
    • 80054748039 scopus 로고    scopus 로고
    • High clonality of virus-specific T lymphocytes defined by TCR usage in the brains of mice infected with West Nile virus
    • COI: 1:CAS:528:DC%2BC3MXht1GmsrzE, PID: 21908734
    • Kitaura K, Fujii Y, Hayasaka D, Matsutani T, Shirai K, Nagata N, et al. High clonality of virus-specific T lymphocytes defined by TCR usage in the brains of mice infected with West Nile virus. J Immunol. 2011;187(8):3919–30. https://doi.org/10.4049/jimmunol.1100442.
    • (2011) J Immunol , vol.187 , Issue.8 , pp. 3919-3930
    • Kitaura, K.1    Fujii, Y.2    Hayasaka, D.3    Matsutani, T.4    Shirai, K.5    Nagata, N.6
  • 62
    • 79251536529 scopus 로고    scopus 로고
    • Antigen-driven patterns of TCR bias are shared across diverse outcomes of human hepatitis C virus infection
    • COI: 1:CAS:528:DC%2BC3MXjs1Onsg%3D%3D, PID: 21160049
    • Miles JJ, Thammanichanond D, Moneer S, Nivarthi UK, Kjer-Nielsen L, Tracy SL, et al. Antigen-driven patterns of TCR bias are shared across diverse outcomes of human hepatitis C virus infection. J Immunol. 2011;186(2):901–12. https://doi.org/10.4049/jimmunol.1003167.
    • (2011) J Immunol , vol.186 , Issue.2 , pp. 901-912
    • Miles, J.J.1    Thammanichanond, D.2    Moneer, S.3    Nivarthi, U.K.4    Kjer-Nielsen, L.5    Tracy, S.L.6
  • 63
    • 84920065951 scopus 로고    scopus 로고
    • Islet-associated T-cell receptor-beta CDR sequence repertoire in prediabetic NOD mice reveals antigen-driven T-cell expansion and shared usage of VbetaJbeta TCR chains
    • COI: 1:CAS:528:DC%2BC2cXhvF2lsbvJ, PID: 25480393
    • Toivonen R, Arstila TP, Hanninen A. Islet-associated T-cell receptor-beta CDR sequence repertoire in prediabetic NOD mice reveals antigen-driven T-cell expansion and shared usage of VbetaJbeta TCR chains. Mol Immunol. 2015;64(1):127–35. https://doi.org/10.1016/j.molimm.2014.11.009.
    • (2015) Mol Immunol , vol.64 , Issue.1 , pp. 127-135
    • Toivonen, R.1    Arstila, T.P.2    Hanninen, A.3
  • 64
    • 77949512969 scopus 로고    scopus 로고
    • Diverse hematological malignancies including Hodgkin-like lymphomas develop in chimeric MHC class II transgenic mice
    • PID: 20046882
    • Raffegerst SH, Hoelzlwimmer G, Kunder S, Mysliwietz J, Quintanilla-Martinez L, Schendel DJ. Diverse hematological malignancies including Hodgkin-like lymphomas develop in chimeric MHC class II transgenic mice. PLoS One. 2009;4(12):e8539. https://doi.org/10.1371/journal.pone.0008539.
    • (2009) PLoS One , vol.4 , Issue.12
    • Raffegerst, S.H.1    Hoelzlwimmer, G.2    Kunder, S.3    Mysliwietz, J.4    Quintanilla-Martinez, L.5    Schendel, D.J.6
  • 65
    • 33846813973 scopus 로고    scopus 로고
    • Mutually exclusive T-cell receptor induction and differential susceptibility to human immunodeficiency virus type 1 mutational escape associated with a two-amino-acid difference between HLA class I subtypes
    • COI: 1:CAS:528:DC%2BD2sXhslKjsrY%3D, PID: 17121793
    • Yu XG, Lichterfeld M, Chetty S, Williams KL, Mui SK, Miura T, et al. Mutually exclusive T-cell receptor induction and differential susceptibility to human immunodeficiency virus type 1 mutational escape associated with a two-amino-acid difference between HLA class I subtypes. J Virol. 2007;81(4):1619–31. https://doi.org/10.1128/jvi.01580-06.
    • (2007) J Virol , vol.81 , Issue.4 , pp. 1619-1631
    • Yu, X.G.1    Lichterfeld, M.2    Chetty, S.3    Williams, K.L.4    Mui, S.K.5    Miura, T.6
  • 66
    • 84899511963 scopus 로고    scopus 로고
    • Conservation of pathogenic TCR homology across class II restrictions in anti-ribonucleoprotein autoimmunity: extended efficacy of T cell vaccine therapy
    • COI: 1:CAS:528:DC%2BC2cXmsVGruro%3D, PID: 24670800
    • Zang Y, Martinez L, Fernandez I, Pignac-Kobinger J, Greidinger EL. Conservation of pathogenic TCR homology across class II restrictions in anti-ribonucleoprotein autoimmunity: extended efficacy of T cell vaccine therapy. J Immunol. 2014;192(9):4093–102. https://doi.org/10.4049/jimmunol.1203197.
    • (2014) J Immunol , vol.192 , Issue.9 , pp. 4093-4102
    • Zang, Y.1    Martinez, L.2    Fernandez, I.3    Pignac-Kobinger, J.4    Greidinger, E.L.5
  • 67
    • 84899748384 scopus 로고    scopus 로고
    • PD-1 identifies the patient-specific CD8(+) tumor-reactive repertoire infiltrating human tumors
    • COI: 1:CAS:528:DC%2BC2cXotVSntrY%3D, PID: 24667641
    • Gros A, Robbins PF, Yao X, Li YF, Turcotte S, Tran E, et al. PD-1 identifies the patient-specific CD8(+) tumor-reactive repertoire infiltrating human tumors. J Clin Invest. 2014;124(5):2246–59. https://doi.org/10.1172/jci73639.
    • (2014) J Clin Invest , vol.124 , Issue.5 , pp. 2246-2259
    • Gros, A.1    Robbins, P.F.2    Yao, X.3    Li, Y.F.4    Turcotte, S.5    Tran, E.6
  • 68
    • 84922839762 scopus 로고    scopus 로고
    • Heterogeneous expansion of CD4+ tumor-infiltrating T-lymphocytes in clear cell renal cell carcinomas
    • COI: 1:CAS:528:DC%2BC2MXitVCmt70%3D, PID: 25637538
    • Zhang Q, Jia Q, Deng T, Song B, Li L. Heterogeneous expansion of CD4+ tumor-infiltrating T-lymphocytes in clear cell renal cell carcinomas. Biochem Biophys Res Commun. 2015;458(1):70–6. https://doi.org/10.1016/j.bbrc.2015.01.069.
    • (2015) Biochem Biophys Res Commun , vol.458 , Issue.1 , pp. 70-76
    • Zhang, Q.1    Jia, Q.2    Deng, T.3    Song, B.4    Li, L.5
  • 69
    • 79953292499 scopus 로고    scopus 로고
    • Quantitative tracking of T cell clones after haematopoietic stem cell transplantation
    • COI: 1:CAS:528:DC%2BC3MXkvVahsLo%3D, PID: 21374820
    • Mamedov IZ, Britanova OV, Bolotin DA, Chkalina AV, Staroverov DB, Zvyagin IV, et al. Quantitative tracking of T cell clones after haematopoietic stem cell transplantation. EMBO Mol Med. 2011;3(4):201–7. https://doi.org/10.1002/emmm.201100129.
    • (2011) EMBO Mol Med , vol.3 , Issue.4 , pp. 201-207
    • Mamedov, I.Z.1    Britanova, O.V.2    Bolotin, D.A.3    Chkalina, A.V.4    Staroverov, D.B.5    Zvyagin, I.V.6
  • 70
    • 77951895272 scopus 로고    scopus 로고
    • Public TCR use by herpes simplex virus-2-specific human CD8 CTLs
    • COI: 1:CAS:528:DC%2BC3cXis1yitr4%3D, PID: 20139278
    • Dong L, Li P, Oenema T, McClurkan CL, Koelle DM. Public TCR use by herpes simplex virus-2-specific human CD8 CTLs. J Immunol. 2010;184(6):3063–71. https://doi.org/10.4049/jimmunol.0903622.
    • (2010) J Immunol , vol.184 , Issue.6 , pp. 3063-3071
    • Dong, L.1    Li, P.2    Oenema, T.3    McClurkan, C.L.4    Koelle, D.M.5
  • 71
    • 0033376778 scopus 로고    scopus 로고
    • Shared structural motifs in TCR of glycopeptide-recognizing T cell hybridomas
    • COI: 1:CAS:528:DyaK1MXlvFOqt7c%3D, PID: 10508250
    • Jensen T, Hansen P, Faurskov Nielsen A, Meldal M, Komba S, Werdelin O. Shared structural motifs in TCR of glycopeptide-recognizing T cell hybridomas. Eur J Immunol. 1999;29(9):2759–68. https://doi.org/10.1002/(sici)1521-4141(199909)29:09<2759::aid-immu2759>3.0.co;2-4.
    • (1999) Eur J Immunol , vol.29 , Issue.9 , pp. 2759-2768
    • Jensen, T.1    Hansen, P.2    Faurskov Nielsen, A.3    Meldal, M.4    Komba, S.5    Werdelin, O.6
  • 72
    • 27944505610 scopus 로고    scopus 로고
    • Avidity for antigen shapes clonal dominance in CD8+ T cell populations specific for persistent DNA viruses
    • COI: 1:CAS:528:DC%2BD2MXht1KqsLnO, PID: 16287711
    • Price DA, Brenchley JM, Ruff LE, Betts MR, Hill BJ, Roederer M, et al. Avidity for antigen shapes clonal dominance in CD8+ T cell populations specific for persistent DNA viruses. J Exp Med. 2005;202(10):1349–61. https://doi.org/10.1084/jem.20051357.
    • (2005) J Exp Med , vol.202 , Issue.10 , pp. 1349-1361
    • Price, D.A.1    Brenchley, J.M.2    Ruff, L.E.3    Betts, M.R.4    Hill, B.J.5    Roederer, M.6
  • 73
    • 41149084984 scopus 로고    scopus 로고
    • Epitope-specific TCRbeta repertoire diversity imparts no functional advantage on the CD8+ T cell response to cognate viral peptides
    • PID: 18238896
    • La Gruta NL, Thomas PG, Webb AI, Dunstone MA, Cukalac T, Doherty PC, et al. Epitope-specific TCRbeta repertoire diversity imparts no functional advantage on the CD8+ T cell response to cognate viral peptides. Proc Natl Acad Sci U S A. 2008;105(6):2034–9. https://doi.org/10.1073/pnas.0711682102.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , Issue.6 , pp. 2034-2039
    • La Gruta, N.L.1    Thomas, P.G.2    Webb, A.I.3    Dunstone, M.A.4    Cukalac, T.5    Doherty, P.C.6
  • 74
    • 84866896058 scopus 로고    scopus 로고
    • Deep sequencing of antiviral T-cell responses to HCMV and EBV in humans reveals a stable repertoire that is maintained for many years
    • COI: 1:STN:280:DC%2BC3s%2FhslOgtQ%3D%3D, PID: 23028307
    • Klarenbeek PL, Remmerswaal EB, ten Berge IJ, Doorenspleet ME, van Schaik BD, Esveldt RE, et al. Deep sequencing of antiviral T-cell responses to HCMV and EBV in humans reveals a stable repertoire that is maintained for many years. PLoS Pathog. 2012;8(9):e1002889. https://doi.org/10.1371/journal.ppat.1002889.
    • (2012) PLoS Pathog , vol.8 , Issue.9
    • Klarenbeek, P.L.1    Remmerswaal, E.B.2    ten Berge, I.J.3    Doorenspleet, M.E.4    van Schaik, B.D.5    Esveldt, R.E.6
  • 75
    • 84863508785 scopus 로고    scopus 로고
    • Emergence of T cells that recognize nonpolymorphic antigens during graft-versus-host disease
    • COI: 1:CAS:528:DC%2BC38XhtFSgtLzP, PID: 22496151
    • Rangarajan H, Yassai M, Subramanian H, Komorowski R, Whitaker M, Gorski J, et al. Emergence of T cells that recognize nonpolymorphic antigens during graft-versus-host disease. Blood. 2012;119(26):6354–64. https://doi.org/10.1182/blood-2012-01-401596.
    • (2012) Blood , vol.119 , Issue.26 , pp. 6354-6364
    • Rangarajan, H.1    Yassai, M.2    Subramanian, H.3    Komorowski, R.4    Whitaker, M.5    Gorski, J.6
  • 76
    • 12244285714 scopus 로고    scopus 로고
    • Clonotype tracking of TCR repertoires during chronic virus infections
    • COI: 1:CAS:528:DC%2BD38Xps12qs7g%3D, PID: 12504586
    • Cohen GB, Islam SA, Noble MS, Lau C, Brander C, Altfeld MA, et al. Clonotype tracking of TCR repertoires during chronic virus infections. Virology. 2002;304(2):474–84.
    • (2002) Virology , vol.304 , Issue.2 , pp. 474-484
    • Cohen, G.B.1    Islam, S.A.2    Noble, M.S.3    Lau, C.4    Brander, C.5    Altfeld, M.A.6
  • 77
    • 58149314573 scopus 로고    scopus 로고
    • Despite biased TRBV gene usage against a dominant HLA B57-restricted epitope, TCR diversity can provide recognition of circulating epitope variants
    • COI: 1:CAS:528:DC%2BD1cXhtFaru7rM, PID: 18802118
    • Simons BC, Vancompernolle SE, Smith RM, Wei J, Barnett L, Lorey SL, et al. Despite biased TRBV gene usage against a dominant HLA B57-restricted epitope, TCR diversity can provide recognition of circulating epitope variants. J Immunol. 2008;181(7):5137–46.
    • (2008) J Immunol , vol.181 , Issue.7 , pp. 5137-5146
    • Simons, B.C.1    Vancompernolle, S.E.2    Smith, R.M.3    Wei, J.4    Barnett, L.5    Lorey, S.L.6
  • 78
    • 65249118742 scopus 로고    scopus 로고
    • Identification of a public CDR3 motif and a biased utilization of T-cell receptor V beta and J beta chains in HLA-A2/Melan-A-specific T-cell clonotypes of melanoma patients
    • PID: 19317896
    • Serana F, Sottini A, Caimi L, Palermo B, Natali PG, Nistico P, et al. Identification of a public CDR3 motif and a biased utilization of T-cell receptor V beta and J beta chains in HLA-A2/Melan-A-specific T-cell clonotypes of melanoma patients. J Transl Med. 2009;7:21. https://doi.org/10.1186/1479-5876-7-21.
    • (2009) J Transl Med , vol.7 , pp. 21
    • Serana, F.1    Sottini, A.2    Caimi, L.3    Palermo, B.4    Natali, P.G.5    Nistico, P.6
  • 79
    • 80052165671 scopus 로고    scopus 로고
    • Escape from highly effective public CD8+ T-cell clonotypes by HIV
    • COI: 1:CAS:528:DC%2BC3MXhtFGisrnF, PID: 21734237
    • Iglesias MC, Almeida JR, Fastenackels S, van Bockel DJ, Hashimoto M, Venturi V, et al. Escape from highly effective public CD8+ T-cell clonotypes by HIV. Blood. 2011;118(8):2138–49. https://doi.org/10.1182/blood-2011-01-328781.
    • (2011) Blood , vol.118 , Issue.8 , pp. 2138-2149
    • Iglesias, M.C.1    Almeida, J.R.2    Fastenackels, S.3    van Bockel, D.J.4    Hashimoto, M.5    Venturi, V.6
  • 80
    • 84939561812 scopus 로고    scopus 로고
    • Chronic graft-versus-host-disease in CD34(+)-humanized NSG mice is associated with human susceptibility HLA haplotypes for autoimmune disease
    • COI: 1:CAS:528:DC%2BC2MXhtFSjsbbL, PID: 26143958
    • Sonntag K, Eckert F, Welker C, Muller H, Muller F, Zips D, et al. Chronic graft-versus-host-disease in CD34(+)-humanized NSG mice is associated with human susceptibility HLA haplotypes for autoimmune disease. J Autoimmun. 2015;62:55–66. https://doi.org/10.1016/j.jaut.2015.06.006.
    • (2015) J Autoimmun , vol.62 , pp. 55-66
    • Sonntag, K.1    Eckert, F.2    Welker, C.3    Muller, H.4    Muller, F.5    Zips, D.6
  • 81
    • 77956920709 scopus 로고    scopus 로고
    • Dacarbazine treatment before peptide vaccination enlarges T-cell repertoire diversity of melan-a-specific, tumor-reactive CTL in melanoma patients
    • COI: 1:CAS:528:DC%2BC3cXhtFGqtrrJ
    • Palermo B, Del Bello D, Sottini A, Serana F, Ghidini C, Gualtieri N, et al. Dacarbazine treatment before peptide vaccination enlarges T-cell repertoire diversity of melan-a-specific, tumor-reactive CTL in melanoma patients. Cancer Rses. 2010;70(18):7084–92. https://doi.org/10.1158/0008-5472.can-10-1326.
    • (2010) Cancer Rses , vol.70 , Issue.18 , pp. 7084-7092
    • Palermo, B.1    Del Bello, D.2    Sottini, A.3    Serana, F.4    Ghidini, C.5    Gualtieri, N.6
  • 82
    • 33745116185 scopus 로고    scopus 로고
    • Early establishment of diverse T cell receptor profiles for influenza-specific CD8(+)CD62L(hi) memory T cells
    • COI: 1:CAS:528:DC%2BD28XmsVWjsbc%3D, PID: 16754852
    • Kedzierska K, Venturi V, Field K, Davenport MP, Turner SJ, Doherty PC. Early establishment of diverse T cell receptor profiles for influenza-specific CD8(+)CD62L(hi) memory T cells. Proc Natl Acad Sci U S A. 2006;103(24):9184–9. https://doi.org/10.1073/pnas.0603289103.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , Issue.24 , pp. 9184-9189
    • Kedzierska, K.1    Venturi, V.2    Field, K.3    Davenport, M.P.4    Turner, S.J.5    Doherty, P.C.6
  • 83
    • 84903638866 scopus 로고    scopus 로고
    • Superimposed epitopes restricted by the same HLA molecule drive distinct HIV-specific CD8+ T cell repertoires
    • COI: 1:CAS:528:DC%2BC2cXhtVWmsb%2FP, PID: 24899498
    • Sun X, Fujiwara M, Shi Y, Kuse N, Gatanaga H, Appay V, et al. Superimposed epitopes restricted by the same HLA molecule drive distinct HIV-specific CD8+ T cell repertoires. J Immunol. 2014;193(1):77–84. https://doi.org/10.4049/jimmunol.1400375.
    • (2014) J Immunol , vol.193 , Issue.1 , pp. 77-84
    • Sun, X.1    Fujiwara, M.2    Shi, Y.3    Kuse, N.4    Gatanaga, H.5    Appay, V.6
  • 84
    • 84939463738 scopus 로고    scopus 로고
    • Oxypurinol-specific T cells possess preferential TCR clonotypes and express granulysin in allopurinol-induced severe cutaneous adverse reactions
    • COI: 1:CAS:528:DC%2BC2MXhtlCisrrO, PID: 25946710
    • Chung WH, Pan RY, Chu MT, Chin SW, Huang YL, Wang WC, et al. Oxypurinol-specific T cells possess preferential TCR clonotypes and express granulysin in allopurinol-induced severe cutaneous adverse reactions. J Invest Dermatol. 2015;135(9):2237–48. https://doi.org/10.1038/jid.2015.165.
    • (2015) J Invest Dermatol. , vol.135 , Issue.9 , pp. 2237-2248
    • Chung, W.H.1    Pan, R.Y.2    Chu, M.T.3    Chin, S.W.4    Huang, Y.L.5    Wang, W.C.6
  • 85
    • 0025791952 scopus 로고
    • T cell receptor genes in a series of class I major histocompatibility complex-restricted cytotoxic T lymphocyte clones specific for a plasmodium berghei nonapeptide: implications for T cell allelic exclusion and antigen-specific repertoire
    • COI: 1:CAS:528:DyaK3MXmt12qt78%3D, PID: 1836010
    • Casanova JL, Romero P, Widmann C, Kourilsky P, Maryanski JL. T cell receptor genes in a series of class I major histocompatibility complex-restricted cytotoxic T lymphocyte clones specific for a plasmodium berghei nonapeptide: implications for T cell allelic exclusion and antigen-specific repertoire. J Exp Med. 1991;174(6):1371–83.
    • (1991) J Exp Med , vol.174 , Issue.6 , pp. 1371-1383
    • Casanova, J.L.1    Romero, P.2    Widmann, C.3    Kourilsky, P.4    Maryanski, J.L.5
  • 86
    • 27144474449 scopus 로고    scopus 로고
    • Selection of T cell clones expressing high-affinity public TCRs within human cytomegalovirus-specific CD8 T cell responses
    • COI: 1:CAS:528:DC%2BD2MXhtFahurfE, PID: 16237109
    • Trautmann L, Rimbert M, Echasserieau K, Saulquin X, Neveu B, Dechanet J, et al. Selection of T cell clones expressing high-affinity public TCRs within human cytomegalovirus-specific CD8 T cell responses. J Immunol. 2005;175(9):6123–32.
    • (2005) J Immunol , vol.175 , Issue.9 , pp. 6123-6132
    • Trautmann, L.1    Rimbert, M.2    Echasserieau, K.3    Saulquin, X.4    Neveu, B.5    Dechanet, J.6
  • 87
    • 84863899032 scopus 로고    scopus 로고
    • The T-cell receptor repertoire of tumor-infiltrating regulatory T lymphocytes is skewed toward public sequences
    • COI: 1:CAS:528:DC%2BC38XhtVeltbrJ, PID: 22573714
    • Sainz-Perez A, Lim A, Lemercier B, Leclerc C. The T-cell receptor repertoire of tumor-infiltrating regulatory T lymphocytes is skewed toward public sequences. Cancer Res. 2012;72(14):3557–69. https://doi.org/10.1158/0008-5472.can-12-0277.
    • (2012) Cancer Res , vol.72 , Issue.14 , pp. 3557-3569
    • Sainz-Perez, A.1    Lim, A.2    Lemercier, B.3    Leclerc, C.4
  • 88
    • 68949086507 scopus 로고    scopus 로고
    • Clonotype selection and composition of human CD8 T cells specific for persistent herpes viruses varies with differentiation but is stable over time
    • COI: 1:CAS:528:DC%2BD1MXnsVOru70%3D, PID: 19542443
    • Iancu EM, Corthesy P, Baumgaertner P, Devevre E, Voelter V, Romero P, et al. Clonotype selection and composition of human CD8 T cells specific for persistent herpes viruses varies with differentiation but is stable over time. J Immunol. 2009;183(1):319–31. https://doi.org/10.4049/jimmunol.0803647.
    • (2009) J Immunol , vol.183 , Issue.1 , pp. 319-331
    • Iancu, E.M.1    Corthesy, P.2    Baumgaertner, P.3    Devevre, E.4    Voelter, V.5    Romero, P.6
  • 89
    • 84883466251 scopus 로고    scopus 로고
    • Tumor-infiltrating lymphocytes in colorectal tumors display a diversity of T cell receptor sequences that differ from the T cells in adjacent mucosal tissue
    • COI: 1:CAS:528:DC%2BC3sXhsFKjtL7M, PID: 23771160
    • Sherwood AM, Emerson RO, Scherer D, Habermann N, Buck K, Staffa J, et al. Tumor-infiltrating lymphocytes in colorectal tumors display a diversity of T cell receptor sequences that differ from the T cells in adjacent mucosal tissue. Cancer Immunol Immunother. 2013;62(9):1453–61. https://doi.org/10.1007/s00262-013-1446-2.
    • (2013) Cancer Immunol Immunother , vol.62 , Issue.9 , pp. 1453-1461
    • Sherwood, A.M.1    Emerson, R.O.2    Scherer, D.3    Habermann, N.4    Buck, K.5    Staffa, J.6
  • 90
    • 71849094775 scopus 로고    scopus 로고
    • Persistence of lung CD8 T cell oligoclonal expansions upon smoking cessation in a mouse model of cigarette smoke-induced emphysema
    • COI: 1:CAS:528:DC%2BD1cXhtl2gsL3P, PID: 19017996
    • Motz GT, Eppert BL, Sun G, Wesselkamper SC, Linke MJ, Deka R, et al. Persistence of lung CD8 T cell oligoclonal expansions upon smoking cessation in a mouse model of cigarette smoke-induced emphysema. J Immunol. 2008;181(11):8036–43.
    • (2008) J Immunol , vol.181 , Issue.11 , pp. 8036-8043
    • Motz, G.T.1    Eppert, B.L.2    Sun, G.3    Wesselkamper, S.C.4    Linke, M.J.5    Deka, R.6
  • 91
    • 0035865217 scopus 로고    scopus 로고
    • Psoriatic arthritis joint fluids are characterized by CD8 and CD4 T cell clonal expansions appear antigen driven
    • COI: 1:CAS:528:DC%2BD3MXht1Ghsbo%3D, PID: 11160357
    • Costello PJ, Winchester RJ, Curran SA, Peterson KS, Kane DJ, Bresnihan B, et al. Psoriatic arthritis joint fluids are characterized by CD8 and CD4 T cell clonal expansions appear antigen driven. J Immunol. 2001;166(4):2878–86.
    • (2001) J Immunol , vol.166 , Issue.4 , pp. 2878-2886
    • Costello, P.J.1    Winchester, R.J.2    Curran, S.A.3    Peterson, K.S.4    Kane, D.J.5    Bresnihan, B.6
  • 92
    • 34247157411 scopus 로고    scopus 로고
    • The lymphocytic infiltration in calcific aortic stenosis predominantly consists of clonally expanded T cells
    • COI: 1:CAS:528:DC%2BD2sXjslWjtb8%3D, PID: 17404318
    • Wu HD, Maurer MS, Friedman RA, Marboe CC, Ruiz-Vazquez EM, Ramakrishnan R, et al. The lymphocytic infiltration in calcific aortic stenosis predominantly consists of clonally expanded T cells. J Immunol. 2007;178(8):5329–39.
    • (2007) J Immunol , vol.178 , Issue.8 , pp. 5329-5339
    • Wu, H.D.1    Maurer, M.S.2    Friedman, R.A.3    Marboe, C.C.4    Ruiz-Vazquez, E.M.5    Ramakrishnan, R.6
  • 93
    • 79251518600 scopus 로고    scopus 로고
    • Genetic and structural basis for selection of a ubiquitous T cell receptor deployed in Epstein-Barr virus infection
    • PID: 21124993
    • Miles JJ, Bulek AM, Cole DK, Gostick E, Schauenburg AJ, Dolton G, et al. Genetic and structural basis for selection of a ubiquitous T cell receptor deployed in Epstein-Barr virus infection. PLoS Pathog. 2010;6(11):e1001198. https://doi.org/10.1371/journal.ppat.1001198.
    • (2010) PLoS Pathog , vol.6 , Issue.11
    • Miles, J.J.1    Bulek, A.M.2    Cole, D.K.3    Gostick, E.4    Schauenburg, A.J.5    Dolton, G.6
  • 94
    • 85017590386 scopus 로고    scopus 로고
    • Sequence and structural analyses reveal distinct and highly diverse human CD8+ TCR repertoires to immunodominant viral antigens
    • COI: 1:CAS:528:DC%2BC2sXmtlWrsLg%3D, PID: 28423320
    • Chen G, Yang X, Ko A, Sun X, Gao M, Zhang Y, et al. Sequence and structural analyses reveal distinct and highly diverse human CD8+ TCR repertoires to immunodominant viral antigens. Cell Rep. 2017;19(3):569–83. https://doi.org/10.1016/j.celrep.2017.03.072.
    • (2017) Cell Rep , vol.19 , Issue.3 , pp. 569-583
    • Chen, G.1    Yang, X.2    Ko, A.3    Sun, X.4    Gao, M.5    Zhang, Y.6
  • 95
    • 0033679109 scopus 로고    scopus 로고
    • Junctional biases in the naive TCR repertoire control the CTL response to an immunodominant determinant of HSV-1
    • COI: 1:CAS:528:DC%2BD3cXjvFGiur8%3D, PID: 10843387
    • Wallace ME, Bryden M, Cose SC, Coles RM, Schumacher TN, Brooks A, et al. Junctional biases in the naive TCR repertoire control the CTL response to an immunodominant determinant of HSV-1. Immunity. 2000;12(5):547–56.
    • (2000) Immunity , vol.12 , Issue.5 , pp. 547-556
    • Wallace, M.E.1    Bryden, M.2    Cose, S.C.3    Coles, R.M.4    Schumacher, T.N.5    Brooks, A.6
  • 96
    • 0034490529 scopus 로고    scopus 로고
    • Persistence of clonal T-cell expansions following high-dose chemotherapy and autologous peripheral blood progenitor cell rescue
    • COI: 1:CAS:528:DC%2BD3MXnsVWntA%3D%3D, PID: 11122136
    • Protheroe AS, Pickard C, Johnson PW, Craddock T, Shefta J, Short K, et al. Persistence of clonal T-cell expansions following high-dose chemotherapy and autologous peripheral blood progenitor cell rescue. Br J Haematol. 2000;111(3):766–73.
    • (2000) Br J Haematol , vol.111 , Issue.3 , pp. 766-773
    • Protheroe, A.S.1    Pickard, C.2    Johnson, P.W.3    Craddock, T.4    Shefta, J.5    Short, K.6
  • 97
    • 0037105512 scopus 로고    scopus 로고
    • TCR rearrangement in lymphocytes infiltrating melanoma metastases after administration of autologous dinitrophenyl-modified vaccine
    • COI: 1:CAS:528:DC%2BD38XntFags7c%3D, PID: 12218163
    • Manne J, Mastrangelo MJ, Sato T, Berd D. TCR rearrangement in lymphocytes infiltrating melanoma metastases after administration of autologous dinitrophenyl-modified vaccine. J Immunol. 2002;169(6):3407–12.
    • (2002) J Immunol , vol.169 , Issue.6 , pp. 3407-3412
    • Manne, J.1    Mastrangelo, M.J.2    Sato, T.3    Berd, D.4
  • 98
    • 84891867784 scopus 로고    scopus 로고
    • Single-cell T-cell receptor-beta analysis of HLA-A*2402-restricted CMV- pp65-specific cytotoxic T-cells in allogeneic hematopoietic SCT
    • COI: 1:CAS:528:DC%2BC2cXmtlWiuw%3D%3D, PID: 23933763
    • Nakasone H, Tanaka Y, Yamazaki R, Terasako K, Sato M, Sakamoto K, et al. Single-cell T-cell receptor-beta analysis of HLA-A*2402-restricted CMV- pp65-specific cytotoxic T-cells in allogeneic hematopoietic SCT. Bone Marrow Transplant. 2014;49(1):87–94. https://doi.org/10.1038/bmt.2013.122.
    • (2014) Bone Marrow Transplant , vol.49 , Issue.1 , pp. 87-94
    • Nakasone, H.1    Tanaka, Y.2    Yamazaki, R.3    Terasako, K.4    Sato, M.5    Sakamoto, K.6
  • 99
    • 1842687400 scopus 로고    scopus 로고
    • Conserved T cell receptor usage in primary and recall responses to an immunodominant influenza virus nucleoprotein epitope
    • COI: 1:CAS:528:DC%2BD2cXjsFCisrY%3D, PID: 15037737
    • Kedzierska K, Turner SJ, Doherty PC. Conserved T cell receptor usage in primary and recall responses to an immunodominant influenza virus nucleoprotein epitope. Proc Natl Acad Sci U S A. 2004;101(14):4942–7. https://doi.org/10.1073/pnas.0401279101.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , Issue.14 , pp. 4942-4947
    • Kedzierska, K.1    Turner, S.J.2    Doherty, P.C.3
  • 100
    • 77956444847 scopus 로고    scopus 로고
    • Transgenic mice with a diverse human T cell antigen receptor repertoire
    • COI: 1:CAS:528:DC%2BC3cXpvVWgs7o%3D, PID: 20693993
    • Li LP, Lampert JC, Chen X, Leitao C, Popovic J, Muller W, et al. Transgenic mice with a diverse human T cell antigen receptor repertoire. Nat Med. 2010;16(9):1029–34. https://doi.org/10.1038/nm.2197.
    • (2010) Nat Med , vol.16 , Issue.9 , pp. 1029-1034
    • Li, L.P.1    Lampert, J.C.2    Chen, X.3    Leitao, C.4    Popovic, J.5    Muller, W.6
  • 101
    • 84949895433 scopus 로고    scopus 로고
    • Multiplex identification of antigen-specific T cell receptors using a combination of immune assays and immune receptor sequencing
    • PID: 26509579
    • Klinger M, Pepin F, Wilkins J, Asbury T, Wittkop T, Zheng J, et al. Multiplex identification of antigen-specific T cell receptors using a combination of immune assays and immune receptor sequencing. PLoS One. 2015;10(10):e0141561. https://doi.org/10.1371/journal.pone.0141561.
    • (2015) PLoS One , vol.10 , Issue.10
    • Klinger, M.1    Pepin, F.2    Wilkins, J.3    Asbury, T.4    Wittkop, T.5    Zheng, J.6
  • 102
    • 84978829537 scopus 로고    scopus 로고
    • Identification of shared TCR sequences from T cells in human breast cancer using emulsion RT-PCR
    • COI: 1:CAS:528:DC%2BC28XpvV2rtr4%3D, PID: 27307436
    • Munson DJ, Egelston CA, Chiotti KE, Parra ZE, Bruno TC, Moore BL, et al. Identification of shared TCR sequences from T cells in human breast cancer using emulsion RT-PCR. Proc Natl Acad Sci U S A. 2016;113(29):8272–7. https://doi.org/10.1073/pnas.1606994113.
    • (2016) Proc Natl Acad Sci U S A , vol.113 , Issue.29 , pp. 8272-8277
    • Munson, D.J.1    Egelston, C.A.2    Chiotti, K.E.3    Parra, Z.E.4    Bruno, T.C.5    Moore, B.L.6
  • 103
    • 0027523064 scopus 로고
    • Characterization of the T cell receptor repertoire causing collagen arthritis in mice
    • COI: 1:CAS:528:DyaK3sXhtVSht7s%3D, PID: 8381155
    • Osman GE, Toda M, Kanagawa O, Hood LE. Characterization of the T cell receptor repertoire causing collagen arthritis in mice. J Exp Med. 1993;177(2):387–95.
    • (1993) J Exp Med , vol.177 , Issue.2 , pp. 387-395
    • Osman, G.E.1    Toda, M.2    Kanagawa, O.3    Hood, L.E.4
  • 104
    • 71849104458 scopus 로고    scopus 로고
    • TCR beta-chain sharing in human CD8+ T cell responses to cytomegalovirus and EBV
    • COI: 1:CAS:528:DC%2BD1cXhtl2gsL%2FO, PID: 19017975
    • Venturi V, Chin HY, Asher TE, Ladell K, Scheinberg P, Bornstein E, et al. TCR beta-chain sharing in human CD8+ T cell responses to cytomegalovirus and EBV. J Immunol. 2008;181(11):7853–62.
    • (2008) J Immunol , vol.181 , Issue.11 , pp. 7853-7862
    • Venturi, V.1    Chin, H.Y.2    Asher, T.E.3    Ladell, K.4    Scheinberg, P.5    Bornstein, E.6
  • 105
    • 0031036659 scopus 로고    scopus 로고
    • Clonal expansion of T lymphocytes in human melanoma metastases after treatment with a hapten-modified autologous tumor vaccine
    • COI: 1:CAS:528:DyaK2sXhtlWhtL8%3D, PID: 9045874
    • Sensi M, Farina C, Maccalli C, Lupetti R, Nicolini G, Anichini A, et al. Clonal expansion of T lymphocytes in human melanoma metastases after treatment with a hapten-modified autologous tumor vaccine. J Clin Invest. 1997;99(4):710–7. https://doi.org/10.1172/jci119215.
    • (1997) J Clin Invest , vol.99 , Issue.4 , pp. 710-717
    • Sensi, M.1    Farina, C.2    Maccalli, C.3    Lupetti, R.4    Nicolini, G.5    Anichini, A.6
  • 106
    • 0034664023 scopus 로고    scopus 로고
    • Frequent contribution of T cell clonotypes with public TCR features to the chronic response against a dominant EBV-derived epitope: application to direct detection of their molecular imprint on the human peripheral T cell repertoire
    • COI: 1:CAS:528:DC%2BD3cXls1KmsLo%3D, PID: 10925283
    • Lim A, Trautmann L, Peyrat MA, Couedel C, Davodeau F, Romagne F, et al. Frequent contribution of T cell clonotypes with public TCR features to the chronic response against a dominant EBV-derived epitope: application to direct detection of their molecular imprint on the human peripheral T cell repertoire. J Immunol. 2000;165(4):2001–11.
    • (2000) J Immunol , vol.165 , Issue.4 , pp. 2001-2011
    • Lim, A.1    Trautmann, L.2    Peyrat, M.A.3    Couedel, C.4    Davodeau, F.5    Romagne, F.6
  • 107
    • 0026343952 scopus 로고
    • Junctional region sequences of T-cell receptor beta-chain genes expressed by pathogenic anti-DNA autoantibody-inducing helper T cells from lupus mice: possible selection by cationic autoantigens
    • COI: 1:CAS:528:DyaK38XhtVChsrs%3D, PID: 1837146
    • Adams S, Leblanc P, Datta SK. Junctional region sequences of T-cell receptor beta-chain genes expressed by pathogenic anti-DNA autoantibody-inducing helper T cells from lupus mice: possible selection by cationic autoantigens. Proc Natl Acad Sci U S A. 1991;88(24):11271–5.
    • (1991) Proc Natl Acad Sci U S A , vol.88 , Issue.24 , pp. 11271-11275
    • Adams, S.1    Leblanc, P.2    Datta, S.K.3
  • 108
    • 0031296851 scopus 로고    scopus 로고
    • Spectratyping of TCRs expressed by CTL-infiltrating minor histocompatibility antigen-disparate allografts
    • COI: 1:CAS:528:DyaK2sXnslKqsLo%3D, PID: 9548462
    • Johnston SL, Borson ND, Wettstein PJ. Spectratyping of TCRs expressed by CTL-infiltrating minor histocompatibility antigen-disparate allografts. J Immunol. 1997;159(11):5233–45.
    • (1997) J Immunol , vol.159 , Issue.11 , pp. 5233-5245
    • Johnston, S.L.1    Borson, N.D.2    Wettstein, P.J.3
  • 109
    • 0037742349 scopus 로고    scopus 로고
    • Restricted T-cell receptor repertoire in melanoma metastases regressing after cytokine therapy
    • COI: 1:CAS:528:DC%2BD3sXltVGrtLg%3D, PID: 12839930
    • Willhauck M, Scheibenbogen C, Pawlita M, Mohler T, Thiel E, Keilholz U. Restricted T-cell receptor repertoire in melanoma metastases regressing after cytokine therapy. Cancer Res. 2003;63(13):3483–5.
    • (2003) Cancer Res , vol.63 , Issue.13 , pp. 3483-3485
    • Willhauck, M.1    Scheibenbogen, C.2    Pawlita, M.3    Mohler, T.4    Thiel, E.5    Keilholz, U.6
  • 110
    • 31544467882 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis in the adjuvant modulates the balance of Th immune response to self-antigen of the CNS without influencing a “core” repertoire of specific T cells
    • COI: 1:CAS:528:DC%2BD28XovVGitw%3D%3D, PID: 16415105
    • Nicolo C, Di Sante G, Orsini M, Rolla S, Columba-Cabezas S, Romano Spica V, et al. Mycobacterium tuberculosis in the adjuvant modulates the balance of Th immune response to self-antigen of the CNS without influencing a “core” repertoire of specific T cells. Int Immunol. 2006;18(2):363–74. https://doi.org/10.1093/intimm/dxh376.
    • (2006) Int Immunol , vol.18 , Issue.2 , pp. 363-374
    • Nicolo, C.1    Di Sante, G.2    Orsini, M.3    Rolla, S.4    Columba-Cabezas, S.5    Romano Spica, V.6
  • 111
    • 80051744672 scopus 로고    scopus 로고
    • T-cell clones expressing different T-cell receptors accumulate in the brains of dying and surviving mice after peripheral infection with far eastern strain of tick-borne encephalitis virus
    • COI: 1:CAS:528:DC%2BC3MXpvFyjsrs%3D, PID: 21830901
    • Fujii Y, Hayasaka D, Kitaura K, Takasaki T, Suzuki R, Kurane I. T-cell clones expressing different T-cell receptors accumulate in the brains of dying and surviving mice after peripheral infection with far eastern strain of tick-borne encephalitis virus. Viral Immunol. 2011;24(4):291–302. https://doi.org/10.1089/vim.2011.0017.
    • (2011) Viral Immunol , vol.24 , Issue.4 , pp. 291-302
    • Fujii, Y.1    Hayasaka, D.2    Kitaura, K.3    Takasaki, T.4    Suzuki, R.5    Kurane, I.6
  • 112
    • 84907069365 scopus 로고    scopus 로고
    • Idiotype-specific Th cells support oligoclonal expansion of anti-dsDNA B cells in mice with lupus
    • COI: 1:CAS:528:DC%2BC2cXhsV2qurvO, PID: 25127856
    • Aas-Hanssen K, Funderud A, Thompson KM, Bogen B, Munthe LA. Idiotype-specific Th cells support oligoclonal expansion of anti-dsDNA B cells in mice with lupus. J Immunol. 2014;193(6):2691–8. https://doi.org/10.4049/jimmunol.1400640.
    • (2014) J Immunol , vol.193 , Issue.6 , pp. 2691-2698
    • Aas-Hanssen, K.1    Funderud, A.2    Thompson, K.M.3    Bogen, B.4    Munthe, L.A.5
  • 113
    • 84912535413 scopus 로고    scopus 로고
    • Epitope specificity delimits the functional capabilities of vaccine-induced CD8 T cell populations
    • COI: 1:CAS:528:DC%2BC2cXhvFCitbzE, PID: 25348625
    • Hill BJ, Darrah PA, Ende Z, Ambrozak DR, Quinn KM, Darko S, et al. Epitope specificity delimits the functional capabilities of vaccine-induced CD8 T cell populations. J Immunol. 2014;193(11):5626–36. https://doi.org/10.4049/jimmunol.1401017.
    • (2014) J Immunol , vol.193 , Issue.11 , pp. 5626-5636
    • Hill, B.J.1    Darrah, P.A.2    Ende, Z.3    Ambrozak, D.R.4    Quinn, K.M.5    Darko, S.6
  • 114
    • 84925487874 scopus 로고    scopus 로고
    • Qualitative differences in brain-infiltrating T cells are associated with a fatal outcome in mice infected with Japanese encephalitis virus
    • COI: 1:CAS:528:DC%2BC2MXht1Ohu7c%3D, PID: 25604524
    • Shirai K, Hayasaka D, Kitaura K, Takasaki T, Morita K, Suzuki R, et al. Qualitative differences in brain-infiltrating T cells are associated with a fatal outcome in mice infected with Japanese encephalitis virus. Arch Virol. 2015;160(3):765–75. https://doi.org/10.1007/s00705-014-2154-8.
    • (2015) Arch Virol , vol.160 , Issue.3 , pp. 765-775
    • Shirai, K.1    Hayasaka, D.2    Kitaura, K.3    Takasaki, T.4    Morita, K.5    Suzuki, R.6
  • 115
    • 84942916791 scopus 로고    scopus 로고
    • Detection and tracking of NY-ESO-1-specific CD8+ T cells by high-throughput T cell receptor beta (TCRB) gene rearrangements sequencing in a peptide-vaccinated patient
    • PID: 26291626
    • Miyai M, Eikawa S, Hosoi A, Iino T, Matsushita H, Isobe M, et al. Detection and tracking of NY-ESO-1-specific CD8+ T cells by high-throughput T cell receptor beta (TCRB) gene rearrangements sequencing in a peptide-vaccinated patient. PLoS One. 2015;10(8):e0136086. https://doi.org/10.1371/journal.pone.0136086.
    • (2015) PLoS One , vol.10 , Issue.8
    • Miyai, M.1    Eikawa, S.2    Hosoi, A.3    Iino, T.4    Matsushita, H.5    Isobe, M.6
  • 116
    • 0030788773 scopus 로고    scopus 로고
    • Epitope-dependent selection of highly restricted or diverse T cell receptor repertoires in response to persistent infection by Epstein-Barr virus
    • COI: 1:STN:280:DyaK2szltFWhsQ%3D%3D, PID: 9207000
    • Campos-Lima PO, Levitsky V, Imreh MP, Gavioli R, Masucci MG. Epitope-dependent selection of highly restricted or diverse T cell receptor repertoires in response to persistent infection by Epstein-Barr virus. J Exp Med. 1997;186(1):83–9.
    • (1997) J Exp Med , vol.186 , Issue.1 , pp. 83-89
    • Campos-Lima, P.O.1    Levitsky, V.2    Imreh, M.P.3    Gavioli, R.4    Masucci, M.G.5
  • 117
    • 0034665325 scopus 로고    scopus 로고
    • Coronary arteries from human cardiac allografts with chronic rejection contain oligoclonal T cells: persistence of identical clonally expanded TCR transcripts from the early post-transplantation period (endomyocardial biopsies) to chronic rejection (coronary arteries)
    • COI: 1:CAS:528:DC%2BD3cXmslynur0%3D, PID: 10975868
    • Slachta CA, Jeevanandam V, Goldman B, Lin WL, Platsoucas CD. Coronary arteries from human cardiac allografts with chronic rejection contain oligoclonal T cells: persistence of identical clonally expanded TCR transcripts from the early post-transplantation period (endomyocardial biopsies) to chronic rejection (coronary arteries). J Immunol. 2000;165(6):3469–83.
    • (2000) J Immunol , vol.165 , Issue.6 , pp. 3469-3483
    • Slachta, C.A.1    Jeevanandam, V.2    Goldman, B.3    Lin, W.L.4    Platsoucas, C.D.5
  • 118
    • 84903783039 scopus 로고    scopus 로고
    • The molecular and functional characterization of clonally expanded CD8+ TCR BV T cells in eosinophilic granulomatosis with polyangiitis (EGPA)
    • COI: 1:CAS:528:DC%2BC2cXmvVWltr8%3D, PID: 24632064
    • Boita M, Guida G, Circosta P, Elia AR, Stella S, Heffler E, et al. The molecular and functional characterization of clonally expanded CD8+ TCR BV T cells in eosinophilic granulomatosis with polyangiitis (EGPA). Clin Immunol. 2014;152(1–2):152–63. https://doi.org/10.1016/j.clim.2014.03.001.
    • (2014) Clin Immunol , vol.152 , Issue.1-2 , pp. 152-163
    • Boita, M.1    Guida, G.2    Circosta, P.3    Elia, A.R.4    Stella, S.5    Heffler, E.6
  • 119
    • 0025744447 scopus 로고
    • Involvement of both T cell receptor V alpha and V beta variable region domains and alpha chain junctional region in viral antigen recognition
    • COI: 1:STN:280:DyaK3MzmsVOqsA%3D%3D, PID: 1716213
    • Brandle D, Burki K, Wallace VA, Rohrer UH, Mak TW, Malissen B, et al. Involvement of both T cell receptor V alpha and V beta variable region domains and alpha chain junctional region in viral antigen recognition. Eur J Immunol. 1991;21(9):2195–202. https://doi.org/10.1002/eji.1830210930.
    • (1991) Eur J Immunol , vol.21 , Issue.9 , pp. 2195-2202
    • Brandle, D.1    Burki, K.2    Wallace, V.A.3    Rohrer, U.H.4    Mak, T.W.5    Malissen, B.6
  • 120
    • 84892386064 scopus 로고    scopus 로고
    • Deep sequencing of the T-cell receptor repertoire in CD8+ T-large granular lymphocyte leukemia identifies signature landscapes
    • COI: 1:CAS:528:DC%2BC3sXhvFOru7bJ, PID: 24149287
    • Clemente MJ, Przychodzen B, Jerez A, Dienes BE, Afable MG, Husseinzadeh H, et al. Deep sequencing of the T-cell receptor repertoire in CD8+ T-large granular lymphocyte leukemia identifies signature landscapes. Blood. 2013;122(25):4077–85. https://doi.org/10.1182/blood-2013-05-506386.
    • (2013) Blood , vol.122 , Issue.25 , pp. 4077-4085
    • Clemente, M.J.1    Przychodzen, B.2    Jerez, A.3    Dienes, B.E.4    Afable, M.G.5    Husseinzadeh, H.6
  • 121
    • 84886439024 scopus 로고    scopus 로고
    • Persistence of EBV antigen-specific CD8 T cell clonotypes during homeostatic immune reconstitution in cancer patients
    • COI: 1:CAS:528:DC%2BC3sXhslWksrrJ, PID: 24205294
    • Iancu EM, Gannon PO, Laurent J, Gupta B, Romero P, Michielin O, et al. Persistence of EBV antigen-specific CD8 T cell clonotypes during homeostatic immune reconstitution in cancer patients. PLoS One. 2013;8(10):e78686. https://doi.org/10.1371/journal.pone.0078686.
    • (2013) PLoS One , vol.8 , Issue.10
    • Iancu, E.M.1    Gannon, P.O.2    Laurent, J.3    Gupta, B.4    Romero, P.5    Michielin, O.6
  • 122
    • 84901259924 scopus 로고    scopus 로고
    • Identification of multiple public TCR repertoires in chronic beryllium disease
    • COI: 1:CAS:528:DC%2BC2cXntlGhurg%3D, PID: 24719461
    • Bowerman NA, Falta MT, Mack DG, Wehrmann F, Crawford F, Mroz MM, et al. Identification of multiple public TCR repertoires in chronic beryllium disease. J Immunol. 2014;192(10):4571–80. https://doi.org/10.4049/jimmunol.1400007.
    • (2014) J Immunol , vol.192 , Issue.10 , pp. 4571-4580
    • Bowerman, N.A.1    Falta, M.T.2    Mack, D.G.3    Wehrmann, F.4    Crawford, F.5    Mroz, M.M.6
  • 123
    • 0032911224 scopus 로고    scopus 로고
    • Analysis of T-cell-receptor beta-chain-gene usage in peripheral-blood and tumor-infiltrating lymphocytes from human non-small-cell lung carcinomas
    • COI: 1:CAS:528:DyaK1MXisVSltro%3D, PID: 10188720
    • Echchakir H, Asselin-Paturel C, Dorothee G, Vergnon I, Grunenwald D, Chouaib S, et al. Analysis of T-cell-receptor beta-chain-gene usage in peripheral-blood and tumor-infiltrating lymphocytes from human non-small-cell lung carcinomas. Int J Cancer. 1999;81(2):205–13.
    • (1999) Int J Cancer , vol.81 , Issue.2 , pp. 205-213
    • Echchakir, H.1    Asselin-Paturel, C.2    Dorothee, G.3    Vergnon, I.4    Grunenwald, D.5    Chouaib, S.6
  • 124
    • 77958134780 scopus 로고    scopus 로고
    • Discrete TCR repertoires and CDR3 features distinguish effector and Foxp3+ regulatory T lymphocytes in myelin oligodendrocyte glycoprotein-induced experimental allergic encephalomyelitis
    • COI: 1:CAS:528:DC%2BC3cXhtFyisrvN, PID: 20810983
    • Nguyen P, Liu W, Ma J, Manirarora JN, Liu X, Cheng C, et al. Discrete TCR repertoires and CDR3 features distinguish effector and Foxp3+ regulatory T lymphocytes in myelin oligodendrocyte glycoprotein-induced experimental allergic encephalomyelitis. J Immunol. 2010;185(7):3895–904. https://doi.org/10.4049/jimmunol.1001550.
    • (2010) J Immunol , vol.185 , Issue.7 , pp. 3895-3904
    • Nguyen, P.1    Liu, W.2    Ma, J.3    Manirarora, J.N.4    Liu, X.5    Cheng, C.6
  • 125
    • 0029051341 scopus 로고
    • Cytotoxic T-lymphocyte clones from different patients display limited T-cell-receptor variable-region gene usage in HLA-A2-restricted recognition of the melanoma antigen Melan-A/MART-1
    • COI: 1:CAS:528:DyaK2MXmtFOgt78%3D, PID: 7777568
    • Sensi M, Traversari C, Radrizzani M, Salvi S, Maccalli C, Mortarini R, et al. Cytotoxic T-lymphocyte clones from different patients display limited T-cell-receptor variable-region gene usage in HLA-A2-restricted recognition of the melanoma antigen Melan-A/MART-1. Proc Natl Acad Sci U S A. 1995;92(12):5674–8.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , Issue.12 , pp. 5674-5678
    • Sensi, M.1    Traversari, C.2    Radrizzani, M.3    Salvi, S.4    Maccalli, C.5    Mortarini, R.6
  • 126
    • 0033976207 scopus 로고    scopus 로고
    • Repertoire dynamics of autoreactive T cells in multiple sclerosis patients and healthy subjects: epitope spreading versus clonal persistence
    • PID: 10686174
    • Goebels N, Hofstetter H, Schmidt S, Brunner C, Wekerle H, Hohlfeld R. Repertoire dynamics of autoreactive T cells in multiple sclerosis patients and healthy subjects: epitope spreading versus clonal persistence. Brain. 2000;123(Pt 3):508–18.
    • (2000) Brain , vol.123 , pp. 508-518
    • Goebels, N.1    Hofstetter, H.2    Schmidt, S.3    Brunner, C.4    Wekerle, H.5    Hohlfeld, R.6
  • 127
    • 80052198797 scopus 로고    scopus 로고
    • High-functional-avidity cytotoxic T lymphocyte responses to HLA-B-restricted Gag-derived epitopes associated with relative HIV control
    • COI: 1:CAS:528:DC%2BC3MXhtFaqsLjI, PID: 21752903
    • Berger CT, Frahm N, Price DA, Mothe B, Ghebremichael M, Hartman KL, et al. High-functional-avidity cytotoxic T lymphocyte responses to HLA-B-restricted Gag-derived epitopes associated with relative HIV control. J Virol. 2011;85(18):9334–45. https://doi.org/10.1128/jvi.00460-11.
    • (2011) J Virol , vol.85 , Issue.18 , pp. 9334-9345
    • Berger, C.T.1    Frahm, N.2    Price, D.A.3    Mothe, B.4    Ghebremichael, M.5    Hartman, K.L.6
  • 128
    • 84961922850 scopus 로고    scopus 로고
    • Peptide/MHC tetramer-based sorting of CD8(+) T cells to a leukemia antigen yields clonotypes drawn nonspecifically from an underlying restricted repertoire
    • COI: 1:CAS:528:DC%2BC2MXjvFenu7c%3D, PID: 25576336
    • Hunsucker SA, McGary CS, Vincent BG, Enyenihi AA, Waugh JP, McKinnon KP, et al. Peptide/MHC tetramer-based sorting of CD8(+) T cells to a leukemia antigen yields clonotypes drawn nonspecifically from an underlying restricted repertoire. Cancer Immunol Res. 2015;3(3):228–35. https://doi.org/10.1158/2326-6066.cir-14-0001.
    • (2015) Cancer Immunol Res , vol.3 , Issue.3 , pp. 228-235
    • Hunsucker, S.A.1    McGary, C.S.2    Vincent, B.G.3    Enyenihi, A.A.4    Waugh, J.P.5    McKinnon, K.P.6
  • 129
    • 0032574783 scopus 로고    scopus 로고
    • On defining the rules for interactions between the T cell receptor and its ligand: a critical role for a specific amino acid residue of the T cell receptor beta chain
    • COI: 1:CAS:528:DyaK1cXivV2jtrY%3D, PID: 9560256
    • Wang F, Ono T, Kalergis AM, Zhang W, DiLorenzo TP, Lim K, et al. On defining the rules for interactions between the T cell receptor and its ligand: a critical role for a specific amino acid residue of the T cell receptor beta chain. Proc Natl Acad Sci U S A. 1998;95(9):5217–22.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , Issue.9 , pp. 5217-5222
    • Wang, F.1    Ono, T.2    Kalergis, A.M.3    Zhang, W.4    DiLorenzo, T.P.5    Lim, K.6
  • 130
    • 65549087573 scopus 로고    scopus 로고
    • Self-antigen-specific CD8+ T cell precursor frequency determines the quality of the antitumor immune response
    • COI: 1:CAS:528:DC%2BD1MXkvVSiu7w%3D, PID: 19332877
    • Rizzuto GA, Merghoub T, Hirschhorn-Cymerman D, Liu C, Lesokhin AM, Sahawneh D, et al. Self-antigen-specific CD8+ T cell precursor frequency determines the quality of the antitumor immune response. J Exp Med. 2009;206(4):849–66. https://doi.org/10.1084/jem.20081382.
    • (2009) J Exp Med , vol.206 , Issue.4 , pp. 849-866
    • Rizzuto, G.A.1    Merghoub, T.2    Hirschhorn-Cymerman, D.3    Liu, C.4    Lesokhin, A.M.5    Sahawneh, D.6
  • 131
    • 68549092730 scopus 로고    scopus 로고
    • Analysis of the conservation of T cell receptor alpha and beta chain variable regions gene in pp65 peptide-specific HLA-A*0201-restricted CD8+ T cells
    • COI: 1:CAS:528:DC%2BC3cXjtVSmtbc%3D, PID: 19403059
    • Luo W, Ma L, Wen Q, Zhou M, Wang X. Analysis of the conservation of T cell receptor alpha and beta chain variable regions gene in pp65 peptide-specific HLA-A*0201-restricted CD8+ T cells. Cell Mol Immunol. 2009;6(2):105–10. https://doi.org/10.1038/cmi.2009.14.
    • (2009) Cell Mol Immunol , vol.6 , Issue.2 , pp. 105-110
    • Luo, W.1    Ma, L.2    Wen, Q.3    Zhou, M.4    Wang, X.5
  • 132
    • 84964992838 scopus 로고    scopus 로고
    • TCR sequencing of single cells reactive to DQ2.5-glia-alpha2 and DQ2.5-glia-omega2 reveals clonal expansion and epitope-specific V-gene usage
    • COI: 1:CAS:528:DC%2BC28XhvFWitrg%3D, PID: 26838051
    • Dahal-Koirala S, Risnes LF, Christophersen A, Sarna VK, Lundin KE, Sollid LM, et al. TCR sequencing of single cells reactive to DQ2.5-glia-alpha2 and DQ2.5-glia-omega2 reveals clonal expansion and epitope-specific V-gene usage. Mucosal Immunol. 2016;9(3):587–96. https://doi.org/10.1038/mi.2015.147.
    • (2016) Mucosal Immunol , vol.9 , Issue.3 , pp. 587-596
    • Dahal-Koirala, S.1    Risnes, L.F.2    Christophersen, A.3    Sarna, V.K.4    Lundin, K.E.5    Sollid, L.M.6
  • 133
    • 0027183869 scopus 로고
    • Evidence for in situ amplification of cytotoxic T-lymphocytes with antitumor activity in a human regressive melanoma
    • COI: 1:STN:280:DyaK3szjvVKlug%3D%3D, PID: 8339262
    • Mackensen A, Ferradini L, Carcelain G, Triebel F, Faure F, Viel S, et al. Evidence for in situ amplification of cytotoxic T-lymphocytes with antitumor activity in a human regressive melanoma. Cancer Res. 1993;53(15):3569–73.
    • (1993) Cancer Res , vol.53 , Issue.15 , pp. 3569-3573
    • Mackensen, A.1    Ferradini, L.2    Carcelain, G.3    Triebel, F.4    Faure, F.5    Viel, S.6
  • 134
    • 0035459214 scopus 로고    scopus 로고
    • Epitope specificity of clonally expanded populations of CD8+ T cells found within the joints of patients with inflammatory arthritis
    • COI: 1:CAS:528:DC%2BD3MXpt12ltrw%3D, PID: 11592365
    • Fazou C, Yang H, McMichael AJ, Callan MF. Epitope specificity of clonally expanded populations of CD8+ T cells found within the joints of patients with inflammatory arthritis. Arthritis Rheum. 2001;44(9):2038–45. https://doi.org/10.1002/1529-0131(200109)44:9<2038::aid-art353>3.0.co;2-1.
    • (2001) Arthritis Rheum , vol.44 , Issue.9 , pp. 2038-2045
    • Fazou, C.1    Yang, H.2    McMichael, A.J.3    Callan, M.F.4
  • 135
    • 8344272118 scopus 로고    scopus 로고
    • In vivo selection of a TCR Vbeta repertoire directed against an immunodominant influenza virus CTL epitope
    • COI: 1:CAS:528:DC%2BD2cXos1Wqtb4%3D, PID: 15351787
    • Zhong W, Reinherz EL. In vivo selection of a TCR Vbeta repertoire directed against an immunodominant influenza virus CTL epitope. Int Immunol. 2004;16(11):1549–59. https://doi.org/10.1093/intimm/dxh156.
    • (2004) Int Immunol , vol.16 , Issue.11 , pp. 1549-1559
    • Zhong, W.1    Reinherz, E.L.2
  • 136
    • 84921488845 scopus 로고    scopus 로고
    • Fixed expression of single influenza virus-specific TCR chains demonstrates the capacity for TCR alpha- and beta-chain diversity in the face of peptide-MHC class I specificity
    • COI: 1:CAS:528:DC%2BC2MXhtVCgs7s%3D, PID: 25535284
    • Clemens EB, Doherty PC, La Gruta NL, Turner SJ. Fixed expression of single influenza virus-specific TCR chains demonstrates the capacity for TCR alpha- and beta-chain diversity in the face of peptide-MHC class I specificity. J Immunol. 2015;194(3):898–910. https://doi.org/10.4049/jimmunol.1401792.
    • (2015) J Immunol , vol.194 , Issue.3 , pp. 898-910
    • Clemens, E.B.1    Doherty, P.C.2    La Gruta, N.L.3    Turner, S.J.4
  • 137
    • 0027234466 scopus 로고
    • Multiplicity of virus-encoded helper T-cell epitopes expressed on FBL-3 tumor cells
    • COI: 1:CAS:528:DyaK2cXisVWqt7s%3D, PID: 7687300
    • Iwashiro M, Kondo T, Shimizu T, Yamagishi H, Takahashi K, Matsubayashi Y, et al. Multiplicity of virus-encoded helper T-cell epitopes expressed on FBL-3 tumor cells. J Virol. 1993;67(8):4533–42.
    • (1993) J Virol , vol.67 , Issue.8 , pp. 4533-4542
    • Iwashiro, M.1    Kondo, T.2    Shimizu, T.3    Yamagishi, H.4    Takahashi, K.5    Matsubayashi, Y.6
  • 138
    • 0027531749 scopus 로고
    • Analysis of T cell receptor variability in tumor-infiltrating lymphocytes from a human regressive melanoma. Evidence for in situ T cell clonal expansion
    • COI: 1:CAS:528:DyaK3sXitlaisLk%3D, PID: 8450047
    • Ferradini L, Mackensen A, Genevee C, Bosq J, Duvillard P, Avril MF, et al. Analysis of T cell receptor variability in tumor-infiltrating lymphocytes from a human regressive melanoma. Evidence for in situ T cell clonal expansion. J Clin Invest. 1993;91(3):1183–90. https://doi.org/10.1172/jci116278.
    • (1993) J Clin Invest , vol.91 , Issue.3 , pp. 1183-1190
    • Ferradini, L.1    Mackensen, A.2    Genevee, C.3    Bosq, J.4    Duvillard, P.5    Avril, M.F.6
  • 139
    • 0033936778 scopus 로고    scopus 로고
    • Quantitation of T-cell receptor frequencies by competitive polymerase chain reaction: dynamics of T-cell clonotype frequencies in an expanding tumor-infiltrating lymphocyte culture
    • COI: 1:CAS:528:DC%2BD3cXlsFWjtLo%3D, PID: 10916751
    • McKee MD, Clay TM, Diamond RA, Rosenberg SA, Nishimura MI. Quantitation of T-cell receptor frequencies by competitive polymerase chain reaction: dynamics of T-cell clonotype frequencies in an expanding tumor-infiltrating lymphocyte culture. J Immunother. 2000;23(4):419–29.
    • (2000) J Immunother , vol.23 , Issue.4 , pp. 419-429
    • McKee, M.D.1    Clay, T.M.2    Diamond, R.A.3    Rosenberg, S.A.4    Nishimura, M.I.5
  • 140
    • 34547662266 scopus 로고    scopus 로고
    • A public T cell clonotype within a heterogeneous autoreactive repertoire is dominant in driving EAE
    • COI: 1:CAS:528:DC%2BD2sXoslOnsrc%3D, PID: 17627303
    • Menezes JS, van den Elzen P, Thornes J, Huffman D, Droin NM, Maverakis E, et al. A public T cell clonotype within a heterogeneous autoreactive repertoire is dominant in driving EAE. J Clin Invest. 2007;117(8):2176–85. https://doi.org/10.1172/jci28277.
    • (2007) J Clin Invest , vol.117 , Issue.8 , pp. 2176-2185
    • Menezes, J.S.1    van den Elzen, P.2    Thornes, J.3    Huffman, D.4    Droin, N.M.5    Maverakis, E.6
  • 141
    • 0025731505 scopus 로고
    • T cell receptor V gene usage of islet beta cell-reactive T cells is not restricted in non-obese diabetic mice
    • COI: 1:CAS:528:DyaK3MXhvVelt7k%3D, PID: 1902501
    • Nakano N, Kikutani H, Nishimoto H, Kishimoto T. T cell receptor V gene usage of islet beta cell-reactive T cells is not restricted in non-obese diabetic mice. J Exp Med. 1991;173(5):1091–7.
    • (1991) J Exp Med , vol.173 , Issue.5 , pp. 1091-1097
    • Nakano, N.1    Kikutani, H.2    Nishimoto, H.3    Kishimoto, T.4
  • 142
    • 0028180226 scopus 로고
    • T-cell receptor usage by melanoma-specific clonal and highly oligoclonal tumor-infiltrating lymphocyte lines
    • COI: 1:CAS:528:DyaK2cXivFKiurY%3D, PID: 7511820
    • Shilyansky J, Nishimura MI, Yannelli JR, Kawakami Y, Jacknin LS, Charmley P, et al. T-cell receptor usage by melanoma-specific clonal and highly oligoclonal tumor-infiltrating lymphocyte lines. Proc Natl Acad Sci U S A. 1994;91(7):2829–33.
    • (1994) Proc Natl Acad Sci U S A , vol.91 , Issue.7 , pp. 2829-2833
    • Shilyansky, J.1    Nishimura, M.I.2    Yannelli, J.R.3    Kawakami, Y.4    Jacknin, L.S.5    Charmley, P.6
  • 143
    • 0027163489 scopus 로고
    • Prominent usage of V beta 8.3 T cells in the H-2Db-restricted response to an influenza A virus nucleoprotein epitope
    • COI: 1:CAS:528:DyaK3sXms1ynsrs%3D, PID: 7689611
    • Deckhut AM, Allan W, McMickle A, Eichelberger M, Blackman MA, Doherty PC, et al. Prominent usage of V beta 8.3 T cells in the H-2Db-restricted response to an influenza A virus nucleoprotein epitope. J Immunol. 1993;151(5):2658–66.
    • (1993) J Immunol , vol.151 , Issue.5 , pp. 2658-2666
    • Deckhut, A.M.1    Allan, W.2    McMickle, A.3    Eichelberger, M.4    Blackman, M.A.5    Doherty, P.C.6
  • 144
    • 0027199885 scopus 로고
    • T cell receptor (TCR) structure of autologous melanoma-reactive cytotoxic T lymphocyte (CTL) clones: tumor-infiltrating lymphocytes overexpress in vivo the TCR beta chain sequence used by an HLA-A2-restricted and melanocyte-lineage-specific CTL clone
    • COI: 1:CAS:528:DyaK2cXnsFelug%3D%3D, PID: 8376931
    • Sensi M, Salvi S, Castelli C, Maccalli C, Mazzocchi A, Mortarini R, et al. T cell receptor (TCR) structure of autologous melanoma-reactive cytotoxic T lymphocyte (CTL) clones: tumor-infiltrating lymphocytes overexpress in vivo the TCR beta chain sequence used by an HLA-A2-restricted and melanocyte-lineage-specific CTL clone. J Exp Med. 1993;178(4):1231–46.
    • (1993) J Exp Med , vol.178 , Issue.4 , pp. 1231-1246
    • Sensi, M.1    Salvi, S.2    Castelli, C.3    Maccalli, C.4    Mazzocchi, A.5    Mortarini, R.6
  • 145
    • 0029791352 scopus 로고    scopus 로고
    • Conserved TCR usage by HLA-Cw* 1601-restricted T cell clones recognizing melanoma antigens
    • COI: 1:CAS:528:DyaK28XlvVyrtro%3D, PID: 8921424
    • Farina C, van der Bruggen P, Boel P, Parmiani G, Sensi M. Conserved TCR usage by HLA-Cw* 1601-restricted T cell clones recognizing melanoma antigens. Int Immunol. 1996;8(9):1463–6.
    • (1996) Int Immunol , vol.8 , Issue.9 , pp. 1463-1466
    • Farina, C.1    van der Bruggen, P.2    Boel, P.3    Parmiani, G.4    Sensi, M.5
  • 146
    • 1442354894 scopus 로고    scopus 로고
    • Multiple sclerosis: brain-infiltrating CD8+ T cells persist as clonal expansions in the cerebrospinal fluid and blood
    • COI: 1:CAS:528:DC%2BD2cXhvVOisbg%3D, PID: 14983026
    • Skulina C, Schmidt S, Dornmair K, Babbe H, Roers A, Rajewsky K, et al. Multiple sclerosis: brain-infiltrating CD8+ T cells persist as clonal expansions in the cerebrospinal fluid and blood. Proc Natl Acad Sci U S A. 2004;101(8):2428–33.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , Issue.8 , pp. 2428-2433
    • Skulina, C.1    Schmidt, S.2    Dornmair, K.3    Babbe, H.4    Roers, A.5    Rajewsky, K.6
  • 147
  • 148
    • 0036093282 scopus 로고    scopus 로고
    • Characterization of human cytomegalovirus peptide-specific CD8(+) T-cell repertoire diversity following in vitro restimulation by antigen-pulsed dendritic cells
    • COI: 1:CAS:528:DC%2BD38XivF2htA%3D%3D, PID: 11756174
    • Peggs K, Verfuerth S, Pizzey A, Ainsworth J, Moss P, Mackinnon S. Characterization of human cytomegalovirus peptide-specific CD8(+) T-cell repertoire diversity following in vitro restimulation by antigen-pulsed dendritic cells. Blood. 2002;99(1):213–23.
    • (2002) Blood , vol.99 , Issue.1 , pp. 213-223
    • Peggs, K.1    Verfuerth, S.2    Pizzey, A.3    Ainsworth, J.4    Moss, P.5    Mackinnon, S.6
  • 149
    • 10344252791 scopus 로고    scopus 로고
    • Selective growth, in vitro and in vivo, of individual T cell clones from tumor-infiltrating lymphocytes obtained from patients with melanoma
    • COI: 1:CAS:528:DC%2BD2cXhtVCqurjN, PID: 15585890
    • Zhou J, Dudley ME, Rosenberg SA, Robbins PF. Selective growth, in vitro and in vivo, of individual T cell clones from tumor-infiltrating lymphocytes obtained from patients with melanoma. J Immunol. 2004;173(12):7622–9.
    • (2004) J Immunol , vol.173 , Issue.12 , pp. 7622-7629
    • Zhou, J.1    Dudley, M.E.2    Rosenberg, S.A.3    Robbins, P.F.4
  • 150
    • 84896775850 scopus 로고    scopus 로고
    • T cell repertoire following autologous stem cell transplantation for multiple sclerosis
    • COI: 1:CAS:528:DC%2BC2cXkt1Wrtr8%3D, PID: 24531550
    • Muraro PA, Robins H, Malhotra S, Howell M, Phippard D, Desmarais C, et al. T cell repertoire following autologous stem cell transplantation for multiple sclerosis. J Clin Invest. 2014;124(3):1168–72. https://doi.org/10.1172/jci71691.
    • (2014) J Clin Invest , vol.124 , Issue.3 , pp. 1168-1172
    • Muraro, P.A.1    Robins, H.2    Malhotra, S.3    Howell, M.4    Phippard, D.5    Desmarais, C.6
  • 151
    • 84940116849 scopus 로고    scopus 로고
    • The T cell repertoire-diversifying enzyme TSSP contributes to thymic selection of diabetogenic CD4 T cell specificities reactive to ChgA and IAPP autoantigens
    • COI: 1:CAS:528:DC%2BC2MXhtlOjur%2FL, PID: 26209627
    • Viret C, Mahiddine K, Baker RL, Haskins K, Guerder S. The T cell repertoire-diversifying enzyme TSSP contributes to thymic selection of diabetogenic CD4 T cell specificities reactive to ChgA and IAPP autoantigens. J Immunol. 2015;195(5):1964–73. https://doi.org/10.4049/jimmunol.1401683.
    • (2015) J Immunol , vol.195 , Issue.5 , pp. 1964-1973
    • Viret, C.1    Mahiddine, K.2    Baker, R.L.3    Haskins, K.4    Guerder, S.5
  • 152
    • 84960155048 scopus 로고    scopus 로고
    • Linking the T cell receptor to the single cell transcriptome in antigen-specific human T cells
    • COI: 1:CAS:528:DC%2BC28Xkt1CktL0%3D, PID: 26860370
    • Eltahla AA, Rizzetto S, Pirozyan MR, Betz-Stablein BD, Venturi V, Kedzierska K, et al. Linking the T cell receptor to the single cell transcriptome in antigen-specific human T cells. Immunol Cell Biol. 2016;94(6):604–11. https://doi.org/10.1038/icb.2016.16.
    • (2016) Immunol Cell Biol , vol.94 , Issue.6 , pp. 604-611
    • Eltahla, A.A.1    Rizzetto, S.2    Pirozyan, M.R.3    Betz-Stablein, B.D.4    Venturi, V.5    Kedzierska, K.6
  • 153
    • 0028574073 scopus 로고
    • HLA-DQ-restricted, islet-specific T-cell clones of a type I diabetic patient. T-cell receptor sequence similarities to insulitis-inducing T-cells of nonobese diabetic mice
    • COI: 1:STN:280:DyaK2M%2FhtFSktg%3D%3D, PID: 7926306
    • Durinovic-Bello I, Steinle A, Ziegler AG, Schendel DJ. HLA-DQ-restricted, islet-specific T-cell clones of a type I diabetic patient. T-cell receptor sequence similarities to insulitis-inducing T-cells of nonobese diabetic mice. Diabetes. 1994;43(11):1318–25.
    • (1994) Diabetes , vol.43 , Issue.11 , pp. 1318-1325
    • Durinovic-Bello, I.1    Steinle, A.2    Ziegler, A.G.3    Schendel, D.J.4
  • 154
    • 0034115382 scopus 로고    scopus 로고
    • Evidence for in situ expansion of diverse antitumor-specific cytotoxic T lymphocyte clones in a human large cell carcinoma of the lung
    • COI: 1:CAS:528:DC%2BD3cXisl2hs7k%3D, PID: 10744655
    • Echchakir H, Vergnon I, Dorothee G, Grunenwald D, Chouaib S, Mami-Chouaib F. Evidence for in situ expansion of diverse antitumor-specific cytotoxic T lymphocyte clones in a human large cell carcinoma of the lung. Int Immunol. 2000;12(4):537–46.
    • (2000) Int Immunol , vol.12 , Issue.4 , pp. 537-546
    • Echchakir, H.1    Vergnon, I.2    Dorothee, G.3    Grunenwald, D.4    Chouaib, S.5    Mami-Chouaib, F.6
  • 155
    • 0037351709 scopus 로고    scopus 로고
    • Characterization of antigen-specific repertoire diversity following in vitro restimulation by a recombinant adenovirus expressing human cytomegalovirus pp65
    • COI: 1:CAS:528:DC%2BD3sXisVChs7s%3D, PID: 12616496
    • Hamel Y, Rohrlich P, Baron V, Bonhomme D, Rieux-Laucat F, Necker A, et al. Characterization of antigen-specific repertoire diversity following in vitro restimulation by a recombinant adenovirus expressing human cytomegalovirus pp65. Eur J Immunol. 2003;33(3):760–8. https://doi.org/10.1002/eji.200323628.
    • (2003) Eur J Immunol , vol.33 , Issue.3 , pp. 760-768
    • Hamel, Y.1    Rohrlich, P.2    Baron, V.3    Bonhomme, D.4    Rieux-Laucat, F.5    Necker, A.6
  • 156
    • 19944434233 scopus 로고    scopus 로고
    • Cooperation of human tumor-reactive CD4+ and CD8+ T cells after redirection of their specificity by a high-affinity p53A2.1-specific TCR
    • COI: 1:CAS:528:DC%2BD2MXht1Cgsbo%3D, PID: 15664164
    • Kuball J, Schmitz FW, Voss RH, Ferreira EA, Engel R, Guillaume P, et al. Cooperation of human tumor-reactive CD4+ and CD8+ T cells after redirection of their specificity by a high-affinity p53A2.1-specific TCR. Immunity. 2005;22(1):117–29. https://doi.org/10.1016/j.immuni.2004.12.005.
    • (2005) Immunity , vol.22 , Issue.1 , pp. 117-129
    • Kuball, J.1    Schmitz, F.W.2    Voss, R.H.3    Ferreira, E.A.4    Engel, R.5    Guillaume, P.6
  • 157
    • 84904300682 scopus 로고    scopus 로고
    • T cell repertoire in DQ5-positive MuSK-positive myasthenia gravis patients
    • COI: 1:CAS:528:DC%2BC2cXivVKisg%3D%3D, PID: 24397960
    • Marino M, Maiuri MT, Di Sante G, Scuderi F, La Carpia F, Trakas N, et al. T cell repertoire in DQ5-positive MuSK-positive myasthenia gravis patients. J Autoimmun. 2014;52:113–21. https://doi.org/10.1016/j.jaut.2013.12.007.
    • (2014) J Autoimmun , vol.52 , pp. 113-121
    • Marino, M.1    Maiuri, M.T.2    Di Sante, G.3    Scuderi, F.4    La Carpia, F.5    Trakas, N.6
  • 158
    • 0031569521 scopus 로고    scopus 로고
    • Diversity of the cytotoxic melanoma-specific immune response: some CTL clones recognize autologous fresh tumor cells and not tumor cell lines
    • COI: 1:CAS:528:DyaK2sXisFCgsrY%3D, PID: 9103444
    • Dufour E, Carcelain G, Gaudin C, Flament C, Avril MF, Faure F. Diversity of the cytotoxic melanoma-specific immune response: some CTL clones recognize autologous fresh tumor cells and not tumor cell lines. J Immunol. 1997;158(8):3787–95.
    • (1997) J Immunol , vol.158 , Issue.8 , pp. 3787-3795
    • Dufour, E.1    Carcelain, G.2    Gaudin, C.3    Flament, C.4    Avril, M.F.5    Faure, F.6
  • 159
    • 0033035367 scopus 로고    scopus 로고
    • A shared TCR CDR3 sequence in NOD mouse autoimmune diabetes
    • COI: 1:CAS:528:DyaK1MXkt1Cjurs%3D, PID: 10360969
    • Tikochinski Y, Elias D, Steeg C, Marcus H, Kantorowitz M, Reshef T, et al. A shared TCR CDR3 sequence in NOD mouse autoimmune diabetes. Int Immunol. 1999;11(6):951–6.
    • (1999) Int Immunol , vol.11 , Issue.6 , pp. 951-956
    • Tikochinski, Y.1    Elias, D.2    Steeg, C.3    Marcus, H.4    Kantorowitz, M.5    Reshef, T.6
  • 160
    • 0036884859 scopus 로고    scopus 로고
    • CD4+ TCR repertoire heterogeneity in Schistosoma mansoni-induced granulomas
    • COI: 1:CAS:528:DC%2BD38Xpt1Klsrc%3D, PID: 12444146
    • Hogan LH, Wang M, Suresh M, Co DO, Weinstock JV, Sandor M. CD4+ TCR repertoire heterogeneity in Schistosoma mansoni-induced granulomas. J Immunol. 2002;169(11):6386–93.
    • (2002) J Immunol , vol.169 , Issue.11 , pp. 6386-6393
    • Hogan, L.H.1    Wang, M.2    Suresh, M.3    Co, D.O.4    Weinstock, J.V.5    Sandor, M.6
  • 161
    • 28844470320 scopus 로고    scopus 로고
    • T-cell grit: large clonal expansions of virus-specific CD8+ T cells can dominate in the peripheral circulation for at least 18 years
    • Miles JJ, Silins SL, Brooks AG, Davis JE, Misko I, Burrows SR. T-cell grit: large clonal expansions of virus-specific CD8+ T cells can dominate in the peripheral circulation for at least 18 years. Blood. 2005;106(13):4412–3.
    • (2005) Blood , vol.106 , Issue.13 , pp. 4412-4413
    • Miles, J.J.1    Silins, S.L.2    Brooks, A.G.3    Davis, J.E.4    Misko, I.5    Burrows, S.R.6
  • 162
    • 0025278329 scopus 로고
    • Preferential usage of V alpha 4 and V beta 10 T cell receptor genes by lymphocytic choriomeningitis virus glycoprotein-specific H-2Db-restricted cytotoxic T cells
    • COI: 1:CAS:528:DyaK3cXitlersrk%3D, PID: 2138558
    • Aebischer T, Oehen S, Hengartner H. Preferential usage of V alpha 4 and V beta 10 T cell receptor genes by lymphocytic choriomeningitis virus glycoprotein-specific H-2Db-restricted cytotoxic T cells. Eur J Immunol. 1990;20(3):523–31. https://doi.org/10.1002/eji.1830200310.
    • (1990) Eur J Immunol , vol.20 , Issue.3 , pp. 523-531
    • Aebischer, T.1    Oehen, S.2    Hengartner, H.3
  • 163
    • 0030054911 scopus 로고    scopus 로고
    • The majority of autologous cytolytic T-lymphocyte clones derived from peripheral blood lymphocytes of a melanoma patient recognize an antigenic peptide derived from gene Pmel17/gp100
    • COI: 1:CAS:528:DyaK28XkvFeisLk%3D, PID: 8752841
    • Zarour H, De Smet C, Lehmann F, Marchand M, Lethe B, Romero P, et al. The majority of autologous cytolytic T-lymphocyte clones derived from peripheral blood lymphocytes of a melanoma patient recognize an antigenic peptide derived from gene Pmel17/gp100. J Invest Dermatol. 1996;107(1):63–7.
    • (1996) J Invest Dermatol , vol.107 , Issue.1 , pp. 63-67
    • Zarour, H.1    De Smet, C.2    Lehmann, F.3    Marchand, M.4    Lethe, B.5    Romero, P.6
  • 164
    • 0034780027 scopus 로고    scopus 로고
    • Circumventing tolerance to a human MDM2-derived tumor antigen by TCR gene transfer
    • COI: 1:CAS:528:DC%2BD3MXnsVCis70%3D, PID: 11577350
    • Stanislawski T, Voss RH, Lotz C, Sadovnikova E, Willemsen RA, Kuball J, et al. Circumventing tolerance to a human MDM2-derived tumor antigen by TCR gene transfer. Nat Immunol. 2001;2(10):962–70. https://doi.org/10.1038/ni1001-962.
    • (2001) Nat Immunol , vol.2 , Issue.10 , pp. 962-970
    • Stanislawski, T.1    Voss, R.H.2    Lotz, C.3    Sadovnikova, E.4    Willemsen, R.A.5    Kuball, J.6
  • 165
    • 33644815011 scopus 로고    scopus 로고
    • The non-palindromic adaptor-PCR method for the identification of the T-cell receptor genes of an interferon-gamma-secreting T-cell hybridomaspecific for trans-sialidase, an immunodominant Trypanosoma cruzi antigen
    • COI: 1:CAS:528:DC%2BD28XjvVagsr4%3D, PID: 16501814
    • Hiyane MI, Boscardin SB, Rodrigues MM. The non-palindromic adaptor-PCR method for the identification of the T-cell receptor genes of an interferon-gamma-secreting T-cell hybridomaspecific for trans-sialidase, an immunodominant Trypanosoma cruzi antigen. Braz J Med Biol Res. 2006;39(3):345–54.
    • (2006) Braz J Med Biol Res , vol.39 , Issue.3 , pp. 345-354
    • Hiyane, M.I.1    Boscardin, S.B.2    Rodrigues, M.M.3
  • 166
    • 85016925751 scopus 로고    scopus 로고
    • Immunosequencing identifies signatures of cytomegalovirus exposure history and HLA-mediated effects on the T cell repertoire
    • COI: 1:CAS:528:DC%2BC2sXltl2rurg%3D, PID: 28369038, This paper represents an essential step toward using immuequencing data to differentiate type 1 diabetes patients from control subjects and ideally to predict disease progression. This paper identified TCRs associated with CMV serostatus, but the concept can likely be applied to type 1 diabetes research given sufficient samples and rescources
    • •• Emerson RO, WS DW, Vignali M, Gravley J, Hu JK, Osborne EJ, et al. Immunosequencing identifies signatures of cytomegalovirus exposure history and HLA-mediated effects on the T cell repertoire. Nat Genet. 2017;49(5):659–65. https://doi.org/10.1038/ng.3822. This paper represents an essential step toward using immunosequencing data to differentiate type 1 diabetes patients from control subjects and ideally to predict disease progression. This paper identified TCRs associated with CMV serostatus, but the concept can likely be applied to type 1 diabetes research given sufficient samples and rescources.
    • (2017) Nat Genet , vol.49 , Issue.5 , pp. 659-665
    • Emerson, R.O.1    Ws, D.W.2    Vignali, M.3    Gravley, J.4    Hu, J.K.5    Osborne, E.J.6
  • 167
    • 84920024469 scopus 로고    scopus 로고
    • Proinsulin-specific, HLA-DQ8, and HLA-DQ8-transdimer-restricted CD4+ T cells infiltrate islets in type 1 diabetes
    • COI: 1:CAS:528:DC%2BC2MXktVOlug%3D%3D, PID: 25157096
    • Pathiraja V, Kuehlich JP, Campbell PD, Krishnamurthy B, Loudovaris T, Coates PT, et al. Proinsulin-specific, HLA-DQ8, and HLA-DQ8-transdimer-restricted CD4+ T cells infiltrate islets in type 1 diabetes. Diabetes. 2015;64(1):172–82. https://doi.org/10.2337/db14-0858.
    • (2015) Diabetes , vol.64 , Issue.1 , pp. 172-182
    • Pathiraja, V.1    Kuehlich, J.P.2    Campbell, P.D.3    Krishnamurthy, B.4    Loudovaris, T.5    Coates, P.T.6
  • 168
    • 85018742541 scopus 로고    scopus 로고
    • Islet-derived CD4 T cells targeting proinsulin in human autoimmune diabetes
    • COI: 1:CAS:528:DC%2BC2sXpvVOhsL0%3D, PID: 27920090, This paper describes autoreactive T cell clones, including epitope reactivities, isolated from the pancreas of human type 1 diabetes organ donors
    • •• Michels AW, Landry LG, McDaniel KA, Yu L, Campbell-Thompson M, Kwok WW, et al. Islet-derived CD4 T cells targeting proinsulin in human autoimmune diabetes. Diabetes. 2017;66(3):722–34. https://doi.org/10.2337/db16-1025. This paper describes autoreactive T cell clones, including epitope reactivities, isolated from the pancreas of human type 1 diabetes organ donors.
    • (2017) Diabetes , vol.66 , Issue.3 , pp. 722-734
    • Michels, A.W.1    Landry, L.G.2    McDaniel, K.A.3    Yu, L.4    Campbell-Thompson, M.5    Kwok, W.W.6
  • 169
    • 84992699812 scopus 로고    scopus 로고
    • Analysis of self-antigen specificity of islet-infiltrating T cells from human donors with type 1 diabetes
    • COI: 1:CAS:528:DC%2BC28XhslCrsLnL, PID: 27798614, This paper describes autoreactive T cell clones, including epitope reactivities, isolated from the pancreas of human type 1 diabetes organ donors
    • •• Babon JA, DeNicola ME, Blodgett DM, Crevecoeur I, Buttrick TS, Maehr R, et al. Analysis of self-antigen specificity of islet-infiltrating T cells from human donors with type 1 diabetes. Nat Med. 2016;22(12):1482–7. https://doi.org/10.1038/nm.4203. This paper describes autoreactive T cell clones, including epitope reactivities, isolated from the pancreas of human type 1 diabetes organ donors.
    • (2016) Nat Med , vol.22 , Issue.12 , pp. 1482-1487
    • Babon, J.A.1    DeNicola, M.E.2    Blodgett, D.M.3    Crevecoeur, I.4    Buttrick, T.S.5    Maehr, R.6
  • 170
    • 84962430639 scopus 로고    scopus 로고
    • Staging presymptomatic type 1 diabetes: a scientific statement of JDRF, the Endocrine Society, and the American Diabetes Association
    • COI: 1:CAS:528:DC%2BC28XmtVCiur8%3D, PID: 26404926, This is a consensus paper describing new clinical staging criteria for the diagis of type 1 diabetes with stage 1 disease being marked by multiple autoantibody positivity without dysglycemia and stage 2 representing the development of dysglycemia without overt symptomatic disease (i.e., type 1 diabetes diagis can be made prior to the requirement for insulin therapy
    • • Insel RA, Dunne JL, Atkinson MA, Chiang JL, Dabelea D, Gottlieb PA, et al. Staging presymptomatic type 1 diabetes: a scientific statement of JDRF, the Endocrine Society, and the American Diabetes Association. Diabetes Care. 2015;38(10):1964–74. https://doi.org/10.2337/dc15-1419. This is a consensus paper describing new clinical staging criteria for the diagnosis of type 1 diabetes with stage 1 disease being marked by multiple autoantibody positivity without dysglycemia and stage 2 representing the development of dysglycemia without overt symptomatic disease (i.e., type 1 diabetes diagnosis can be made prior to the requirement for insulin therapy).
    • (2015) Diabetes Care , vol.38 , Issue.10 , pp. 1964-1974
    • Insel, R.A.1    Dunne, J.L.2    Atkinson, M.A.3    Chiang, J.L.4    Dabelea, D.5    Gottlieb, P.A.6
  • 171
    • 84892752839 scopus 로고    scopus 로고
    • Type 1 diabetes
    • PID: 23890997
    • Atkinson MA, Eisenbarth GS, Michels AW. Type 1 diabetes. Lancet. 2014;383(9911):69–82. https://doi.org/10.1016/S0140-6736(13)60591-7.
    • (2014) Lancet , vol.383 , Issue.9911 , pp. 69-82
    • Atkinson, M.A.1    Eisenbarth, G.S.2    Michels, A.W.3
  • 172
    • 0022617990 scopus 로고
    • Diabetes mellitus. A chronic autoimmune disease
    • COI: 1:STN:280:DyaL283gtlCrsw%3D%3D, PID: 3517648
    • Eisenbarth GS, Type I. Diabetes mellitus. A chronic autoimmune disease. N Engl J Med. 1986;314(21):1360–8. https://doi.org/10.1056/NEJM198605223142106.
    • (1986) N Engl J Med , vol.314 , Issue.21 , pp. 1360-1368
    • Eisenbarth, G.S.1    Type, I.2
  • 173
    • 85014513366 scopus 로고    scopus 로고
    • Autoimmunity against a defective ribosomal insulin gene product in type 1 diabetes
    • COI: 1:CAS:528:DC%2BC2sXkvFahsbs%3D, PID: 28263308, Seminal report of Defective Ribosomal Insulin Products (DRiPs) as novel autoantigens for type 1 diabetes
    • •• Kracht MJ, van Lummel M, Nikolic T, Joosten AM, Laban S, van der Slik AR, et al. Autoimmunity against a defective ribosomal insulin gene product in type 1 diabetes. Nat Med. 2017;23(4):501–7. https://doi.org/10.1038/nm.4289. Seminal report of Defective Ribosomal Insulin Products (DRiPs) as novel autoantigens for type 1 diabetes.
    • (2017) Nat Med , vol.23 , Issue.4 , pp. 501-507
    • Kracht, M.J.1    van Lummel, M.2    Nikolic, T.3    Joosten, A.M.4    Laban, S.5    van der Slik, A.R.6
  • 174
    • 84957922058 scopus 로고    scopus 로고
    • Pathogenic CD4 T cells in type 1 diabetes recognize epitopes formed by peptide fusion
    • COI: 1:CAS:528:DC%2BC28Xit1OjsLw%3D, PID: 26912858, Seminal report of hybrid insulin peptides (HIPs) as novel autoantigens for type 1 diabetes
    • •• Delong T, Wiles TA, Baker RL, Bradley B, Barbour G, Reisdorph R, et al. Pathogenic CD4 T cells in type 1 diabetes recognize epitopes formed by peptide fusion. Science. 2016;351(6274):711–4. https://doi.org/10.1126/science.aad2791. Seminal report of hybrid insulin peptides (HIPs) as novel autoantigens for type 1 diabetes.
    • (2016) Science , vol.351 , Issue.6274 , pp. 711-714
    • Delong, T.1    Wiles, T.A.2    Baker, R.L.3    Bradley, B.4    Barbour, G.5    Reisdorph, R.6
  • 175
    • 84939812788 scopus 로고    scopus 로고
    • High-throughput pairing of T cell receptor alpha and beta sequences
    • PID: 26290413, This paper describes a key stride toward the ability to pair TCR alpha and beta chain sequences for TCR reconstruction
    • •• Howie B, Sherwood AM, Berkebile AD, Berka J, Emerson RO, Williamson DW, et al. High-throughput pairing of T cell receptor alpha and beta sequences. Sci Transl Med. 2015;7(301):301ra131. https://doi.org/10.1126/scitranslmed.aac5624. This paper describes a key stride toward the ability to pair TCR alpha and beta chain sequences for TCR reconstruction.
    • (2015) Sci Transl Med , vol.7 , Issue.301 , pp. 301ra131
    • Howie, B.1    Sherwood, A.M.2    Berkebile, A.D.3    Berka, J.4    Emerson, R.O.5    Williamson, D.W.6
  • 176
    • 85031422093 scopus 로고    scopus 로고
    • Accessed 30 June 2017
    • Manual CSTU. http://www.clontech.com/xxclt_ibcGetAttachment.jsp?cItemId=114424. Accessed 30 June 2017.
    • Manual CSTU
  • 179
    • 85031405956 scopus 로고    scopus 로고
    • Accessed 30 June 2017
    • pRESTO. https://pypi.python.org/pypi/presto. Accessed 30 June 2017.
    • pRESTO
  • 180
    • 85031401326 scopus 로고    scopus 로고
    • Accessed 30 June 2017
    • IgBLAST. ftp://ftp.ncbi.nih.gov/blast/executables/igblast/release/. Accessed 30 June 2017.
    • IgBLAST
  • 182
    • 85031408190 scopus 로고    scopus 로고
    • Accessed 30 June 2017
    • MIGMAP. https://github.com/mikessh/migmap. Accessed 30 June 2017.
    • MIGMAP
  • 183
    • 85031428201 scopus 로고    scopus 로고
    • Accessed 30 June 2017
    • Decombinator. https://innate2adaptive.github.io/Decombinator/. Accessed 30 June 2017.
    • Decombinator
  • 184
    • 84874671063 scopus 로고    scopus 로고
    • Decombinator: a tool for fast, efficient gene assignment in T-cell receptor sequences using a finite state machine
    • COI: 1:CAS:528:DC%2BC3sXjtlGgtr4%3D, PID: 23303508
    • Thomas N, Heather J, Ndifon W, Shawe-Taylor J, Chain B. Decombinator: a tool for fast, efficient gene assignment in T-cell receptor sequences using a finite state machine. Bioinformatics. 2013;29(5):542–50. https://doi.org/10.1093/bioinformatics/btt004.
    • (2013) Bioinformatics , vol.29 , Issue.5 , pp. 542-550
    • Thomas, N.1    Heather, J.2    Ndifon, W.3    Shawe-Taylor, J.4    Chain, B.5
  • 185
    • 84960194523 scopus 로고    scopus 로고
    • T cell fate and clonality inference from single-cell transcriptomes
    • PID: 26950746
    • Stubbington MJ, Lonnberg T, Proserpio V, Clare S, Speak AO, Dougan G, et al. T cell fate and clonality inference from single-cell transcriptomes. Nat Methods. 2016;13(4):329–32. https://doi.org/10.1038/nmeth.3800.
    • (2016) Nat Methods , vol.13 , Issue.4 , pp. 329-332
    • Stubbington, M.J.1    Lonnberg, T.2    Proserpio, V.3    Clare, S.4    Speak, A.O.5    Dougan, G.6
  • 186
    • 85031411572 scopus 로고    scopus 로고
    • Accessed 30 June 2017
    • TraCeR. https://github.com/teichlab/tracer. Accessed 30 June 2017.
    • TraCeR
  • 188
    • 85031433100 scopus 로고    scopus 로고
    • Accessed 30 June 2017
    • MiGEC. https://github.com/mikessh/migec. Accessed 30 June 2017.
    • MiGEC
  • 189
    • 84941759089 scopus 로고    scopus 로고
    • IMSEQ--a fast and error aware approach to immunogenetic sequence analysis
    • COI: 1:CAS:528:DC%2BC28Xht1CitrfI, PID: 25987567
    • Kuchenbecker L, Nienen M, Hecht J, Neumann AU, Babel N, Reinert K, et al. IMSEQ--a fast and error aware approach to immunogenetic sequence analysis. Bioinformatics. 2015;31(18):2963–71. https://doi.org/10.1093/bioinformatics/btv309.
    • (2015) Bioinformatics , vol.31 , Issue.18 , pp. 2963-2971
    • Kuchenbecker, L.1    Nienen, M.2    Hecht, J.3    Neumann, A.U.4    Babel, N.5    Reinert, K.6
  • 190
    • 85031414458 scopus 로고    scopus 로고
    • Accessed 30 June 2017
    • ImSeq. http://www.imtools.org/. Accessed 30 June 2017.
    • ImSeq. /
  • 191
    • 84995528759 scopus 로고    scopus 로고
    • RTCR: a pipeline for complete and accurate recovery of T cell repertoires from high throughput sequencing data
    • COI: 1:CAS:528:DC%2BC2sXht1ajtb3J, PID: 27324198
    • Gerritsen B, Pandit A, Andeweg AC, de Boer RJ. RTCR: a pipeline for complete and accurate recovery of T cell repertoires from high throughput sequencing data. Bioinformatics. 2016;32(20):3098–106. https://doi.org/10.1093/bioinformatics/btw339.
    • (2016) Bioinformatics , vol.32 , Issue.20 , pp. 3098-3106
    • Gerritsen, B.1    Pandit, A.2    Andeweg, A.C.3    de Boer, R.J.4
  • 192
    • 85031429991 scopus 로고    scopus 로고
    • Accessed 30 June 2017
    • RTCR. https://github.com/uubram/RTCR. Accessed 30 June 2017.
    • RTCR
  • 194
    • 85031416755 scopus 로고    scopus 로고
    • Accessed 30 June 2017
    • MiXCR. https://mixcr.readthedocs.io/en/latest/quickstart.html. Accessed 30 June 2017.
    • MiXCR
  • 195
    • 84990817455 scopus 로고    scopus 로고
    • VDJML: a file format with tools for capturing the results of inferring immune receptor rearrangements
    • PID: 27766961
    • Toby IT, Levin MK, Salinas EA, Christley S, Bhattacharya S, Breden F, et al. VDJML: a file format with tools for capturing the results of inferring immune receptor rearrangements. BMC Bioinformatics. 2016;17(Suppl 13):333. https://doi.org/10.1186/s12859-016-1214-3.
    • (2016) BMC Bioinformatics. , vol.17 , pp. 333
    • Toby, I.T.1    Levin, M.K.2    Salinas, E.A.3    Christley, S.4    Bhattacharya, S.5    Breden, F.6
  • 196
    • 85031415341 scopus 로고    scopus 로고
    • Accessed 30 June 2017
    • VDJserver. https://vdjserver.org. Accessed 30 June 2017.
    • VDJserver
  • 197
    • 77950541195 scopus 로고    scopus 로고
    • Comprehensive assessment of T-cell receptor β-chain diversity in αβ T cells
    • COI: 1:CAS:528:DC%2BD1MXhsVGku7vN, PID: 19706884
    • Robins HS, Campregher PV, Srivastava SK, Wacher A, Turtle CJ, Kahsai O, et al. Comprehensive assessment of T-cell receptor β-chain diversity in αβ T cells. Blood. 2009;114(19):4099–107. https://doi.org/10.1182/blood-2009-04-217604.
    • (2009) Blood , vol.114 , Issue.19 , pp. 4099-4107
    • Robins, H.S.1    Campregher, P.V.2    Srivastava, S.K.3    Wacher, A.4    Turtle, C.J.5    Kahsai, O.6
  • 198
    • 85031396034 scopus 로고    scopus 로고
    • Accessed 30 June 2017
    • immunoSEQ. http://www.adaptivebiotech.com/immunoseq/. Accessed 30 June 2017.
    • immunoSEQ
  • 199
    • 85031419624 scopus 로고    scopus 로고
    • Accessed 30 June 2017
    • iPair. http://www.irepertoire.com/ipair. Accessed 30 June 2017.
    • iPair
  • 200
    • 85014633289 scopus 로고    scopus 로고
    • The repertoire dissimilarity index as a method to compare lymphocyte receptor repertoires
    • PID: 28264647
    • Bolen CR, Rubelt F, Vander Heiden JA, Davis MM. The repertoire dissimilarity index as a method to compare lymphocyte receptor repertoires. BMC Bioinformatics. 2017;18(1):155. https://doi.org/10.1186/s12859-017-1556-5.
    • (2017) BMC Bioinformatics. , vol.18 , Issue.1 , pp. 155
    • Bolen, C.R.1    Rubelt, F.2    Vander Heiden, J.A.3    Davis, M.M.4
  • 201
    • 85031433001 scopus 로고    scopus 로고
    • Accessed 30 June 2017
    • RDI. https://bitbucket.org/cbolen1/rdicore/. Accessed 30 June 2017.
    • RDI
  • 203
    • 85031400756 scopus 로고    scopus 로고
    • Accessed 30 June 2017
    • TCRdist. https://github.com/phbradley/tcr-dist. Accessed 30 June 2017.
    • TCRdist
  • 204
    • 85031414927 scopus 로고    scopus 로고
    • Accessed 30 June 2017
    • iRweb. http://www.irepertoire.com/irweb. Accessed 30 June 2017.
    • iRweb
  • 205
    • 85031427178 scopus 로고    scopus 로고
    • Accessed 30 June 2017
    • Loupe. https://support.10xgenomics.com/genome-exome/software/visualization/latest/what-is-loupe. Accessed 30 June 2017.
    • Loupe
  • 207
    • 85031433607 scopus 로고    scopus 로고
    • Accessed 30 June 2017
    • tcR. https://imminfo.github.io/tcr. Accessed 30 June 2017.
    • tcR
  • 209
    • 85031401117 scopus 로고    scopus 로고
    • Accessed 30 June 2017
    • VDJtools. https://vdjtools-doc.readthedocs.io/en/latest/intro.html. Accessed 30 June 2017.
    • VDJtools
  • 211
    • 85031395413 scopus 로고    scopus 로고
    • Accessed 30 June 2017
    • VDJviz. https://github.com/antigenomics/vdjviz. Accessed 30 June 2017.
    • VDJviz
  • 212
    • 84991687024 scopus 로고    scopus 로고
    • High throughput sequencing reveals the diversity of TRB-CDR3 repertoire in patients with psoriasis vulgaris
    • COI: 1:CAS:528:DC%2BC28Xhs1yqsLrN, PID: 27743555
    • Cao X, Wa Q, Wang Q, Li L, Liu X, An L, et al. High throughput sequencing reveals the diversity of TRB-CDR3 repertoire in patients with psoriasis vulgaris. Int Immunopharmacol. 2016;40:487–91. https://doi.org/10.1016/j.intimp.2016.10.004.
    • (2016) Int Immunopharmacol , vol.40 , pp. 487-491
    • Cao, X.1    Wa, Q.2    Wang, Q.3    Li, L.4    Liu, X.5    An, L.6
  • 213
    • 84978525300 scopus 로고    scopus 로고
    • High-throughput sequencing reveals immunological characteristics of the TRB-/IgH-CDR3 region of umbilical cord blood
    • COI: 1:CAS:528:DC%2BC28XhtFSit7nO, PID: 27373756
    • Guo C, Wang Q, Cao X, Yang Y, Liu X, An L, et al. High-throughput sequencing reveals immunological characteristics of the TRB-/IgH-CDR3 region of umbilical cord blood. J Pediatr. 2016;176:69–78.e1. https://doi.org/10.1016/j.jpeds.2016.05.078.
    • (2016) J Pediatr , vol.176 , pp. 69-78.e1
    • Guo, C.1    Wang, Q.2    Cao, X.3    Yang, Y.4    Liu, X.5    An, L.6
  • 214
    • 85014936523 scopus 로고    scopus 로고
    • ClonoCalc and ClonoPlot: immune repertoire analysis from raw files to publication figures with graphical user interface
    • PID: 28284194
    • Fahnrich A, Krebbel M, Decker N, Leucker M, Lange FD, Kalies K, et al. ClonoCalc and ClonoPlot: immune repertoire analysis from raw files to publication figures with graphical user interface. BMC Bioinformatics. 2017;18(1):164. https://doi.org/10.1186/s12859-017-1575-2.
    • (2017) BMC Bioinformatics , vol.18 , Issue.1 , pp. 164
    • Fahnrich, A.1    Krebbel, M.2    Decker, N.3    Leucker, M.4    Lange, F.D.5    Kalies, K.6
  • 215
    • 84945220306 scopus 로고    scopus 로고
    • RNA sequencing and analysis
    • PID: 25870306
    • Kukurba K, Montgomery S. RNA sequencing and analysis. Cold Spring Harb Protoc. 2015;2015(11):951–69.
    • (2015) Cold Spring Harb Protoc , vol.2015 , Issue.11 , pp. 951-969
    • Kukurba, K.1    Montgomery, S.2
  • 216
    • 84893833939 scopus 로고    scopus 로고
    • Beyond model antigens: high-dimensional methods for the analysis of antigen-specific T cells
    • COI: 1:CAS:528:DC%2BC2cXps1Kgsg%3D%3D, PID: 24441473
    • Newell EW, Davis MM. Beyond model antigens: high-dimensional methods for the analysis of antigen-specific T cells. Nat Biotechnol. 2014;32(2):149–57. https://doi.org/10.1038/nbt.2783.
    • (2014) Nat Biotechnol , vol.32 , Issue.2 , pp. 149-157
    • Newell, E.W.1    Davis, M.M.2
  • 217
    • 85009446777 scopus 로고    scopus 로고
    • Massively parallel digital transcriptional profiling of single cells
    • COI: 1:CAS:528:DC%2BC2sXht1WlsLo%3D, PID: 28091601, This paper reports single-cell immuequencing which will be an imperative step toward identifying cell function/phenotype along with TCR clone/reactivity
    • •• Zheng GXY, Terry JM, Belgrader P, Ryvkin P, Bent ZW, Wilson R, et al. Massively parallel digital transcriptional profiling of single cells. Nat Commun. 2017;8:14049. https://doi.org/10.1038/ncomms14049. This paper reports single-cell immunosequencing which will be an imperative step toward identifying cell function/phenotype along with TCR clone/reactivity.
    • (2017) Nat Commun , vol.8 , pp. 14049
    • Zheng, G.X.Y.1    Terry, J.M.2    Belgrader, P.3    Ryvkin, P.4    Bent, Z.W.5    Wilson, R.6
  • 218
    • 84879114358 scopus 로고    scopus 로고
    • Seroconversion to multiple islet autoantibodies and risk of progression to diabetes in children
    • COI: 1:CAS:528:DC%2BC3sXhtFCrsLnL, PID: 23780460
    • Ziegler AG, Rewers M, Simell O, Simell T, Lempainen J, Steck A, et al. Seroconversion to multiple islet autoantibodies and risk of progression to diabetes in children. JAMA. 2013;309(23):2473–9. https://doi.org/10.1001/jama.2013.6285.
    • (2013) JAMA , vol.309 , Issue.23 , pp. 2473-2479
    • Ziegler, A.G.1    Rewers, M.2    Simell, O.3    Simell, T.4    Lempainen, J.5    Steck, A.6
  • 219
    • 84879831638 scopus 로고    scopus 로고
    • Immunologic and metabolic biomarkers of beta-cell destruction in the diagnosis of type 1 diabetes
    • PID: 22675665
    • Lebastchi J, Herold KC. Immunologic and metabolic biomarkers of beta-cell destruction in the diagnosis of type 1 diabetes. Cold Spring Harb Perspect Med. 2012;2(6):a007708. https://doi.org/10.1101/cshperspect.a007708.
    • (2012) Cold Spring Harb Perspect Med , vol.2 , Issue.6 , pp. a007708
    • Lebastchi, J.1    Herold, K.C.2
  • 220
    • 84997284732 scopus 로고    scopus 로고
    • Minimal residual disease detection and evolved IGH clones analysis in acute B lymphoblastic leukemia using IGH deep sequencing
    • PID: 27757113, This paper supports the notion that immuequencing offers sufficient specificity and sensitivity to potentially detect minimal resisual autoimmune disease (similar to monitoring MRD in leukemia patients). This suggests that immuequencing could be used to monitor patients’ response to therapy and determine if a redose may be necessary
    • • Wu J, Jia S, Wang C, Zhang W, Liu S, Zeng X, et al. Minimal residual disease detection and evolved IGH clones analysis in acute B lymphoblastic leukemia using IGH deep sequencing. Front Immunol. 2016;7:403. https://doi.org/10.3389/fimmu.2016.00403. This paper supports the notion that immunosequencing offers sufficient specificity and sensitivity to potentially detect minimal resisual autoimmune disease (similar to monitoring MRD in leukemia patients). This suggests that immunosequencing could be used to monitor patients’ response to therapy and determine if a redose may be necessary.
    • (2016) Front Immunol , vol.7 , pp. 403
    • Wu, J.1    Jia, S.2    Wang, C.3    Zhang, W.4    Liu, S.5    Zeng, X.6
  • 221
    • 84891685285 scopus 로고    scopus 로고
    • Minimal residual disease monitoring with high-throughput sequencing of T cell receptors in cutaneous T cell lymphoma
    • PID: 24307695
    • Weng WK, Armstrong R, Arai S, Desmarais C, Hoppe R, Kim YH. Minimal residual disease monitoring with high-throughput sequencing of T cell receptors in cutaneous T cell lymphoma. Sci Transl Med. 2013;5(214):214ra171. https://doi.org/10.1126/scitranslmed.3007420.
    • (2013) Sci Transl Med , vol.5 , Issue.214 , pp. 214ra171
    • Weng, W.K.1    Armstrong, R.2    Arai, S.3    Desmarais, C.4    Hoppe, R.5    Kim, Y.H.6
  • 222
    • 84905579254 scopus 로고    scopus 로고
    • Immunoglobulin and T cell receptor gene high-throughput sequencing quantifies minimal residual disease in acute lymphoblastic leukemia and predicts post-transplantation relapse and survival
    • COI: 1:CAS:528:DC%2BC2cXhtVWrsL%2FJ, PID: 24769317
    • Logan AC, Vashi N, Faham M, Carlton V, Kong K, Buno I, et al. Immunoglobulin and T cell receptor gene high-throughput sequencing quantifies minimal residual disease in acute lymphoblastic leukemia and predicts post-transplantation relapse and survival. Biol Blood Marrow Transplant. 2014;20(9):1307–13. https://doi.org/10.1016/j.bbmt.2014.04.018.
    • (2014) Biol Blood Marrow Transplant. , vol.20 , Issue.9 , pp. 1307-1313
    • Logan, A.C.1    Vashi, N.2    Faham, M.3    Carlton, V.4    Kong, K.5    Buno, I.6
  • 223
    • 84871525322 scopus 로고    scopus 로고
    • Deep-sequencing approach for minimal residual disease detection in acute lymphoblastic leukemia
    • COI: 1:CAS:528:DC%2BC3sXms1eksA%3D%3D, PID: 23074282
    • Faham M, Zheng J, Moorhead M, Carlton VE, Stow P, Coustan-Smith E, et al. Deep-sequencing approach for minimal residual disease detection in acute lymphoblastic leukemia. Blood. 2012;120(26):5173–80. https://doi.org/10.1182/blood-2012-07-444042.
    • (2012) Blood , vol.120 , Issue.26 , pp. 5173-5180
    • Faham, M.1    Zheng, J.2    Moorhead, M.3    Carlton, V.E.4    Stow, P.5    Coustan-Smith, E.6
  • 224
    • 36448978896 scopus 로고    scopus 로고
    • Type 1 diabetes as a relapsing-remitting disease?
    • von Herrath M, Sanda S, Herold K. Type 1 diabetes as a relapsing-remitting disease? Nat Rev Immunol. 2007;7(12):988–94. https://doi.org/10.1038/nri2192.
    • (2007) Nat Rev Immunol. , vol.7 , Issue.12 , pp. 988-994
    • von Herrath, M.1    Sanda, S.2    Herold, K.3
  • 225
    • 85025671708 scopus 로고    scopus 로고
    • Thelin MA, Kissler S, Vigneault F, Watters AL, White Det al. In vivo enrichment of diabetogenic T cells. Diabetes. 2017;
    • Thelin MA, Kissler S, Vigneault F, Watters AL, White D, Koshy ST, et al. In vivo enrichment of diabetogenic T cells. Diabetes. 2017; https://doi.org/10.2337/db16-0946.
    • Koshy ST
  • 226
    • 0015161920 scopus 로고
    • Efficacy of antilymphocyte globulin in cadaver renal transplantation
    • COI: 1:STN:280:DyaE38%2Fks1ahtA%3D%3D, PID: 4941300
    • Belzer FO, Schweizer RT, Cho S, Cochrum KC, Moberg A, Kountz SL. Efficacy of antilymphocyte globulin in cadaver renal transplantation. Surg Forum. 1971;22:223–4.
    • (1971) Surg Forum , vol.22 , pp. 223-224
    • Belzer, F.O.1    Schweizer, R.T.2    Cho, S.3    Cochrum, K.C.4    Moberg, A.5    Kountz, S.L.6
  • 227
    • 0015033141 scopus 로고
    • Controlled clinical trial of antilymphocyte globulin in human renal allografts
    • COI: 1:STN:280:DyaE38%2Fgs1yitw%3D%3D, PID: 4937969
    • Birtch AG, Carpenter CB, Tilney NL, Hampers CL, Hager FB, Levine L, et al. Controlled clinical trial of antilymphocyte globulin in human renal allografts. Transplant Proc. 1971;3(1):762–5.
    • (1971) Transplant Proc , vol.3 , Issue.1 , pp. 762-765
    • Birtch, A.G.1    Carpenter, C.B.2    Tilney, N.L.3    Hampers, C.L.4    Hager, F.B.5    Levine, L.6
  • 228
  • 229
    • 0035097170 scopus 로고    scopus 로고
    • Cyclophosphamide and antithymocyte globulin to condition patients with aplastic anemia for allogeneic marrow transplantations: the experience in four centers
    • COI: 1:STN:280:DC%2BD3M3jtlWrtg%3D%3D, PID: 11215697
    • Storb R, Blume KG, O'Donnell MR, Chauncey T, Forman SJ, Deeg HJ, et al. Cyclophosphamide and antithymocyte globulin to condition patients with aplastic anemia for allogeneic marrow transplantations: the experience in four centers. Biol Blood Marrow Transplant. 2001;7(1):39–44. https://doi.org/10.1053/bbmt.2001.v7.pm11215697.
    • (2001) Biol Blood Marrow Transplant , vol.7 , Issue.1 , pp. 39-44
    • Storb, R.1    Blume, K.G.2    O'Donnell, M.R.3    Chauncey, T.4    Forman, S.J.5    Deeg, H.J.6
  • 230
    • 0011243682 scopus 로고    scopus 로고
    • Single-bolus high-dose ATG for prophylaxis of rejection in renal transplantation—a prospective, randomized study
    • PID: 11112016
    • Yussim A, Shapira Z. Single-bolus high-dose ATG for prophylaxis of rejection in renal transplantation—a prospective, randomized study. Transpl Int. 2000;13(Suppl 1):S293–4.
    • (2000) Transpl Int , vol.13 , pp. S293-S294
    • Yussim, A.1    Shapira, Z.2
  • 231
    • 84987942213 scopus 로고    scopus 로고
    • Further understanding of the immunopathology of multiple sclerosis: impact on future treatments
    • COI: 1:CAS:528:DC%2BC28XhtVGmtrvN, PID: 27191526
    • Bhise V, Dhib-Jalbut S. Further understanding of the immunopathology of multiple sclerosis: impact on future treatments. Expert Rev Clin Immunol. 2016;12(10):1069–89. https://doi.org/10.1080/1744666x.2016.1191351.
    • (2016) Expert Rev Clin Immunol , vol.12 , Issue.10 , pp. 1069-1089
    • Bhise, V.1    Dhib-Jalbut, S.2
  • 232
    • 84959105807 scopus 로고    scopus 로고
    • Novel immunotherapeutic avenues for rheumatoid arthritis
    • COI: 1:CAS:528:DC%2BC28XhvFSku7k%3D, PID: 26875450
    • Semerano L, Minichiello E, Bessis N, Boissier MC. Novel immunotherapeutic avenues for rheumatoid arthritis. Trends Mol Med. 2016;22(3):214–29. https://doi.org/10.1016/j.molmed.2016.01.005.
    • (2016) Trends Mol Med , vol.22 , Issue.3 , pp. 214-229
    • Semerano, L.1    Minichiello, E.2    Bessis, N.3    Boissier, M.C.4
  • 233
    • 84887025288 scopus 로고    scopus 로고
    • Anti-CD3 clinical trials in type 1 diabetes mellitus
    • COI: 1:CAS:528:DC%2BC3sXosVGmsr8%3D, PID: 23726024
    • Daifotis AG, Koenig S, Chatenoud L, Herold KC. Anti-CD3 clinical trials in type 1 diabetes mellitus. Clin Immunol. 2013;149(3):268–78. https://doi.org/10.1016/j.clim.2013.05.001.
    • (2013) Clin Immunol , vol.149 , Issue.3 , pp. 268-278
    • Daifotis, A.G.1    Koenig, S.2    Chatenoud, L.3    Herold, K.C.4
  • 234
    • 84865478468 scopus 로고    scopus 로고
    • Rapamycin/IL-2 combination therapy in patients with type 1 diabetes augments Tregs yet transiently impairs beta-cell function
    • Long SA, Rieck M, Sanda S, Bollyky JB, Samuels PL, Goland R, et al. Rapamycin/IL-2 combination therapy in patients with type 1 diabetes augments Tregs yet transiently impairs beta-cell function. Diabetes. 2012; https://doi.org/10.2337/db12-0049.
    • (2012) Diabetes
    • Long, S.A.1    Rieck, M.2    Sanda, S.3    Bollyky, J.B.4    Samuels, P.L.5    Goland, R.6
  • 235
    • 77950636402 scopus 로고    scopus 로고
    • Failure to preserve beta-cell function with mycophenolate mofetil and daclizumab combined therapy in patients with new- onset type 1 diabetes
    • COI: 1:CAS:528:DC%2BC3cXlsleqtLo%3D, PID: 20067954
    • Gottlieb PA, Quinlan S, Krause-Steinrauf H, Greenbaum CJ, Wilson DM, Rodriguez H, et al. Failure to preserve beta-cell function with mycophenolate mofetil and daclizumab combined therapy in patients with new- onset type 1 diabetes. Diabetes Care. 2010;33(4):826–32. https://doi.org/10.2337/dc09-1349.
    • (2010) Diabetes Care , vol.33 , Issue.4 , pp. 826-832
    • Gottlieb, P.A.1    Quinlan, S.2    Krause-Steinrauf, H.3    Greenbaum, C.J.4    Wilson, D.M.5    Rodriguez, H.6
  • 236
    • 79960912796 scopus 로고    scopus 로고
    • Co-stimulation modulation with abatacept in patients with recent-onset type 1 diabetes: a randomised, double-blind, placebo-controlled trial
    • COI: 1:CAS:528:DC%2BC3MXpsFeju70%3D, PID: 21719096
    • Orban T, Bundy B, Becker DJ, DiMeglio LA, Gitelman SE, Goland R, et al. Co-stimulation modulation with abatacept in patients with recent-onset type 1 diabetes: a randomised, double-blind, placebo-controlled trial. Lancet. 2011;378(9789):412–9. https://doi.org/10.1016/S0140-6736(11)60886-6.
    • (2011) Lancet , vol.378 , Issue.9789 , pp. 412-419
    • Orban, T.1    Bundy, B.2    Becker, D.J.3    DiMeglio, L.A.4    Gitelman, S.E.5    Goland, R.6
  • 237
    • 84879517841 scopus 로고    scopus 로고
    • Immune-directed therapy for type 1 diabetes at the clinical level: the Immune Tolerance Network (ITN) experience
    • PID: 23804273
    • Ehlers MR, Nepom GT. Immune-directed therapy for type 1 diabetes at the clinical level: the Immune Tolerance Network (ITN) experience. Rev Diabet Stud. 2012;9(4):359–71. https://doi.org/10.1900/rds.2012.9.359.
    • (2012) Rev Diabet Stud , vol.9 , Issue.4 , pp. 359-371
    • Ehlers, M.R.1    Nepom, G.T.2
  • 238
    • 84878300647 scopus 로고    scopus 로고
    • Interleukin-1 antagonism in type 1 diabetes of recent onset: two multicentre, randomised, double-blind, placebo-controlled trials
    • COI: 1:CAS:528:DC%2BC3sXls1Sit7s%3D, PID: 23562090
    • Moran A, Bundy B, Becker DJ, DiMeglio LA, Gitelman SE, Goland R, et al. Interleukin-1 antagonism in type 1 diabetes of recent onset: two multicentre, randomised, double-blind, placebo-controlled trials. Lancet. 2013;381(9881):1905–15. https://doi.org/10.1016/S0140-6736(13)60023-9.
    • (2013) Lancet , vol.381 , Issue.9881 , pp. 1905-1915
    • Moran, A.1    Bundy, B.2    Becker, D.J.3    DiMeglio, L.A.4    Gitelman, S.E.5    Goland, R.6
  • 239
    • 0022619110 scopus 로고
    • Cyclosporin increases the rate and length of remissions in insulin-dependent diabetes of recent onset: results of a multicentre double-blind trial
    • Feutren G, Assan R, Karsenty G, Du Rostu H, Sirmai J, Papos L, et al. Cyclosporin increases the rate and length of remissions in insulin-dependent diabetes of recent onset: results of a multicentre double-blind trial. Lancet. 1986;328(8499):119–24. https://doi.org/10.1016/S0140-6736(86)91943-4.
    • (1986) Lancet , vol.328 , Issue.8499 , pp. 119-124
    • Feutren, G.1    Assan, R.2    Karsenty, G.3    Du Rostu, H.4    Sirmai, J.5    Papos, L.6
  • 240
    • 0021929456 scopus 로고
    • Metabolic and immunological effects of cyclosporin in recently diagnosed type 1 diabetes mellitus
    • COI: 1:STN:280:DyaL2M%2FosFWnug%3D%3D, PID: 2857024
    • Assan R, Feutren G, Debray-Sachs M, Quiniou-Debrie MC, Laborie C, Thomas G, et al. Metabolic and immunological effects of cyclosporin in recently diagnosed type 1 diabetes mellitus. Lancet. 1985;1(8420):67–71.
    • (1985) Lancet , vol.1 , Issue.8420 , pp. 67-71
    • Assan, R.1    Feutren, G.2    Debray-Sachs, M.3    Quiniou-Debrie, M.C.4    Laborie, C.5    Thomas, G.6
  • 241
    • 77955653658 scopus 로고    scopus 로고
    • Cyclosporin and methotrexate therapy induces remission in type 1 diabetes mellitus
    • COI: 1:CAS:528:DC%2BC3cXptleit7o%3D, PID: 20440520
    • Sobel DO, Henzke A, Abbassi V. Cyclosporin and methotrexate therapy induces remission in type 1 diabetes mellitus. Acta Diabetol. 2010;47(3):243–50. https://doi.org/10.1007/s00592-010-0188-2.
    • (2010) Acta Diabetol , vol.47 , Issue.3 , pp. 243-250
    • Sobel, D.O.1    Henzke, A.2    Abbassi, V.3
  • 242
    • 84887055430 scopus 로고    scopus 로고
    • Teplizumab preserves C-peptide in recent-onset type 1 diabetes: two-year results from the randomized, placebo-controlled Protege trial
    • COI: 1:CAS:528:DC%2BC3sXhsleisr3P, PID: 23801579
    • Hagopian W, Ferry RJ Jr, Sherry N, Carlin D, Bonvini E, Johnson S, et al. Teplizumab preserves C-peptide in recent-onset type 1 diabetes: two-year results from the randomized, placebo-controlled Protege trial. Diabetes. 2013;62(11):3901–8. https://doi.org/10.2337/db13-0236.
    • (2013) Diabetes , vol.62 , Issue.11 , pp. 3901-3908
    • Hagopian, W.1    Ferry, R.J.2    Sherry, N.3    Carlin, D.4    Bonvini, E.5    Johnson, S.6
  • 243
    • 84887052291 scopus 로고    scopus 로고
    • Teplizumab (anti-CD3 mAb) treatment preserves C-peptide responses in patients with new-onset type 1 diabetes in a randomized controlled trial: metabolic and immunologic features at baseline identify a subgroup of responders
    • COI: 1:CAS:528:DC%2BC3sXhsleisr7J, PID: 23835333
    • Herold KC, Gitelman SE, Ehlers MR, Gottlieb PA, Greenbaum CJ, Hagopian W, et al. Teplizumab (anti-CD3 mAb) treatment preserves C-peptide responses in patients with new-onset type 1 diabetes in a randomized controlled trial: metabolic and immunologic features at baseline identify a subgroup of responders. Diabetes. 2013;62(11):3766–74. https://doi.org/10.2337/db13-0345.
    • (2013) Diabetes , vol.62 , Issue.11 , pp. 3766-3774
    • Herold, K.C.1    Gitelman, S.E.2    Ehlers, M.R.3    Gottlieb, P.A.4    Greenbaum, C.J.5    Hagopian, W.6
  • 244
    • 84876095279 scopus 로고    scopus 로고
    • Teplizumab treatment may improve C-peptide responses in participants with type 1 diabetes after the new-onset period: a randomised controlled trial
    • COI: 1:CAS:528:DC%2BC3sXlt1Gqsw%3D%3D, PID: 23086558
    • Herold KC, Gitelman SE, Willi SM, Gottlieb PA, Waldron-Lynch F, Devine L, et al. Teplizumab treatment may improve C-peptide responses in participants with type 1 diabetes after the new-onset period: a randomised controlled trial. Diabetologia. 2013;56(2):391–400. https://doi.org/10.1007/s00125-012-2753-4.
    • (2013) Diabetologia , vol.56 , Issue.2 , pp. 391-400
    • Herold, K.C.1    Gitelman, S.E.2    Willi, S.M.3    Gottlieb, P.A.4    Waldron-Lynch, F.5    Devine, L.6
  • 245
    • 84897851090 scopus 로고    scopus 로고
    • Costimulation modulation with abatacept in patients with recent-onset type 1 diabetes: follow-up 1 year after cessation of treatment
    • COI: 1:CAS:528:DC%2BC2cXosVSltLs%3D, PID: 24296850
    • Orban T, Bundy B, Becker DJ, Dimeglio LA, Gitelman SE, Goland R, et al. Costimulation modulation with abatacept in patients with recent-onset type 1 diabetes: follow-up 1 year after cessation of treatment. Diabetes Care. 2014;37(4):1069–75. https://doi.org/10.2337/dc13-0604.
    • (2014) Diabetes Care , vol.37 , Issue.4 , pp. 1069-1075
    • Orban, T.1    Bundy, B.2    Becker, D.J.3    Dimeglio, L.A.4    Gitelman, S.E.5    Goland, R.6
  • 246
    • 84920413163 scopus 로고    scopus 로고
    • Anti-thymocyte globulin/G-CSF treatment preserves β cell function in patients with established type 1 diabetes
    • PID: 25500887
    • Haller MJ, Gitelman SE, Gottlieb PA, Michels AW, Rosenthal SM, Shuster JJ, et al. Anti-thymocyte globulin/G-CSF treatment preserves β cell function in patients with established type 1 diabetes. J Clin Invest. 2015;125(1):448–55. https://doi.org/10.1172/JCI78492.
    • (2015) J Clin Invest , vol.125 , Issue.1 , pp. 448-455
    • Haller, M.J.1    Gitelman, S.E.2    Gottlieb, P.A.3    Michels, A.W.4    Rosenthal, S.M.5    Shuster, J.J.6
  • 247
    • 85000502393 scopus 로고    scopus 로고
    • Antithymocyte globulin plus G-CSF combination therapy leads to sustained immunomodulatory and metabolic effects in a subset of responders with established type 1 diabetes
    • COI: 1:CAS:528:DC%2BC2sXitV2htLY%3D, PID: 27669730
    • Haller MJ, Gitelman SE, Gottlieb PA, Michels AW, Perry DJ, Schultz AR, et al. Antithymocyte globulin plus G-CSF combination therapy leads to sustained immunomodulatory and metabolic effects in a subset of responders with established type 1 diabetes. Diabetes. 2016;65(12):3765–75. https://doi.org/10.2337/db16-0823.
    • (2016) Diabetes , vol.65 , Issue.12 , pp. 3765-3775
    • Haller, M.J.1    Gitelman, S.E.2    Gottlieb, P.A.3    Michels, A.W.4    Perry, D.J.5    Schultz, A.R.6
  • 248
    • 84955291992 scopus 로고    scopus 로고
    • Interleukin-1 antagonism moderates the inflammatory state associated with type 1 diabetes during clinical trials conducted at disease onset
    • COI: 1:CAS:528:DC%2BC28XhtFWhsbo%3D, PID: 26692253
    • Cabrera SM, Wang X, Chen YG, Jia S, Kaldunski ML, Greenbaum CJ, et al. Interleukin-1 antagonism moderates the inflammatory state associated with type 1 diabetes during clinical trials conducted at disease onset. Eur J Immunol. 2016;46(4):1030–46. https://doi.org/10.1002/eji.201546005.
    • (2016) Eur J Immunol , vol.46 , Issue.4 , pp. 1030-1046
    • Cabrera, S.M.1    Wang, X.2    Chen, Y.G.3    Jia, S.4    Kaldunski, M.L.5    Greenbaum, C.J.6
  • 249
    • 84962673275 scopus 로고    scopus 로고
    • Antithymocyte globulin therapy for patients with recent-onset type 1 diabetes: 2 year results of a randomised trial
    • Gitelman SE, Gottlieb PA, Felner EI, Willi SM, Fisher LK, Moran A, et al. Antithymocyte globulin therapy for patients with recent-onset type 1 diabetes: 2 year results of a randomised trial. Diabetologia. 2016; https://doi.org/10.1007/s00125-016-3917-4.
    • (2016) Diabetologia
    • Gitelman, S.E.1    Gottlieb, P.A.2    Felner, E.I.3    Willi, S.M.4    Fisher, L.K.5    Moran, A.6
  • 250
    • 84939218518 scopus 로고    scopus 로고
    • Alefacept provides sustained clinical and immunological effects in new-onset type 1 diabetes patients
    • PID: 26193635
    • Rigby MR, Harris KM, Pinckney A, DiMeglio LA, Rendell MS, Felner EI, et al. Alefacept provides sustained clinical and immunological effects in new-onset type 1 diabetes patients. J Clin Invest. 2015;125(8):3285–96. https://doi.org/10.1172/jci81722.
    • (2015) J Clin Invest , vol.125 , Issue.8 , pp. 3285-3296
    • Rigby, M.R.1    Harris, K.M.2    Pinckney, A.3    DiMeglio, L.A.4    Rendell, M.S.5    Felner, E.I.6
  • 251
    • 34247154341 scopus 로고    scopus 로고
    • Autologous nonmyeloablative hematopoietic stem cell transplantation in newly diagnosed type 1 diabetes mellitus
    • COI: 1:CAS:528:DC%2BD2sXktFeitL0%3D, PID: 17426276
    • Voltarelli JC, Couri CE, Stracieri AB, Oliveira MC, Moraes DA, Pieroni F, et al. Autologous nonmyeloablative hematopoietic stem cell transplantation in newly diagnosed type 1 diabetes mellitus. JAMA. 2007;297(14):1568–76. https://doi.org/10.1001/jama.297.14.1568.
    • (2007) JAMA , vol.297 , Issue.14 , pp. 1568-1576
    • Voltarelli, J.C.1    Couri, C.E.2    Stracieri, A.B.3    Oliveira, M.C.4    Moraes, D.A.5    Pieroni, F.6
  • 252
    • 84906674143 scopus 로고    scopus 로고
    • Autologous nonmyeloablative hematopoietic stem cell transplantation in new-onset type 1 diabetes: a multicenter analysis
    • PID: 24947362
    • D’Addio F, Valderrama Vasquez A, Ben Nasr M, Franek E, Zhu D, Li L, et al. Autologous nonmyeloablative hematopoietic stem cell transplantation in new-onset type 1 diabetes: a multicenter analysis. Diabetes. 2014;63(9):3041–6. https://doi.org/10.2337/db14-0295.
    • (2014) Diabetes , vol.63 , Issue.9 , pp. 3041-3046
    • D’Addio, F.1    Valderrama Vasquez, A.2    Ben Nasr, M.3    Franek, E.4    Zhu, D.5    Li, L.6
  • 253
    • 34250777773 scopus 로고    scopus 로고
    • Mechanisms of action of antithymocyte globulin: T-cell depletion and beyond
    • COI: 1:CAS:528:DC%2BD2sXms1Wnu7o%3D, PID: 17410187
    • Mohty M. Mechanisms of action of antithymocyte globulin: T-cell depletion and beyond. Leukemia. 2007;21(7):1387–94. https://doi.org/10.1038/sj.leu.2404683.
    • (2007) Leukemia , vol.21 , Issue.7 , pp. 1387-1394
    • Mohty, M.1
  • 254
    • 84908021698 scopus 로고    scopus 로고
    • G-CSF: from granulopoietic stimulant to bone marrow stem cell mobilizing agent
    • COI: 1:CAS:528:DC%2BC2cXhtleiurrO, PID: 25131807
    • Bendall LJ, Bradstock KF. G-CSF: from granulopoietic stimulant to bone marrow stem cell mobilizing agent. Cytokine Growth Factor Rev. 2014;25(4):355–67. https://doi.org/10.1016/j.cytogfr.2014.07.011.
    • (2014) Cytokine Growth Factor Rev , vol.25 , Issue.4 , pp. 355-367
    • Bendall, L.J.1    Bradstock, K.F.2
  • 255
    • 85016554390 scopus 로고    scopus 로고
    • Development of CAR T cells designed to improve antitumor efficacy and safety, Pharmacol Ther
    • Jaspers JE, Brentjens RJ. Development of CAR T cells designed to improve antitumor efficacy and safety. Pharmacol Ther. 2017; https://doi.org/10.1016/j.pharmthera.2017.03.012.
    • (2017) Brentjens RJ
    • Jaspers, J.E.1
  • 256
    • 85015649083 scopus 로고    scopus 로고
    • Current approaches to increase CAR T cell potency in solid tumors: targeting the tumor microenvironment
    • PID: 28331617
    • Scarfo I, Maus MV. Current approaches to increase CAR T cell potency in solid tumors: targeting the tumor microenvironment. J Immunother Cancer. 2017;5:28. https://doi.org/10.1186/s40425-017-0230-9.
    • (2017) J Immunother Cancer , vol.5 , pp. 28
    • Scarfo, I.1    Maus, M.V.2
  • 257
    • 84923019006 scopus 로고    scopus 로고
    • T cells expressing CD19 chimeric antigen receptors for acute lymphoblastic leukaemia in children and young adults: a phase 1 dose-escalation trial
    • COI: 1:CAS:528:DC%2BC2cXhslGjtLbM, PID: 25319501
    • Lee DW, Kochenderfer JN, Stetler-Stevenson M, Cui YK, Delbrook C, Feldman SA, et al. T cells expressing CD19 chimeric antigen receptors for acute lymphoblastic leukaemia in children and young adults: a phase 1 dose-escalation trial. Lancet. 2015;385(9967):517–28. https://doi.org/10.1016/s0140-6736(14)61403-3.
    • (2015) Lancet , vol.385 , Issue.9967 , pp. 517-528
    • Lee, D.W.1    Kochenderfer, J.N.2    Stetler-Stevenson, M.3    Cui, Y.K.4    Delbrook, C.5    Feldman, S.A.6
  • 258
    • 78549278144 scopus 로고    scopus 로고
    • Eradication of B-lineage cells and regression of lymphoma in a patient treated with autologous T cells genetically engineered to recognize CD19
    • COI: 1:CAS:528:DC%2BC3cXhsFCiu7fK, PID: 20668228
    • Kochenderfer JN, Wilson WH, Janik JE, Dudley ME, Stetler-Stevenson M, Feldman SA, et al. Eradication of B-lineage cells and regression of lymphoma in a patient treated with autologous T cells genetically engineered to recognize CD19. Blood. 2010;116(20):4099–102. https://doi.org/10.1182/blood-2010-04-281931.
    • (2010) Blood , vol.116 , Issue.20 , pp. 4099-4102
    • Kochenderfer, J.N.1    Wilson, W.H.2    Janik, J.E.3    Dudley, M.E.4    Stetler-Stevenson, M.5    Feldman, S.A.6
  • 259
    • 78549253550 scopus 로고    scopus 로고
    • Multiple injections of electroporated autologous T cells expressing a chimeric antigen receptor mediate regression of human disseminated tumor
    • COI: 1:CAS:528:DC%2BC3cXhsVWmsL3F, PID: 20926399
    • Zhao Y, Moon E, Carpenito C, Paulos CM, Liu X, Brennan AL, et al. Multiple injections of electroporated autologous T cells expressing a chimeric antigen receptor mediate regression of human disseminated tumor. Cancer Res. 2010;70(22):9053–61. https://doi.org/10.1158/0008-5472.can-10-2880.
    • (2010) Cancer Res , vol.70 , Issue.22 , pp. 9053-9061
    • Zhao, Y.1    Moon, E.2    Carpenito, C.3    Paulos, C.M.4    Liu, X.5    Brennan, A.L.6
  • 260
    • 67349284360 scopus 로고    scopus 로고
    • Transfer of mRNA encoding recombinant immunoreceptors reprograms CD4+ and CD8+ T cells for use in the adoptive immunotherapy of cancer
    • COI: 1:CAS:528:DC%2BD1MXosVWkuw%3D%3D, PID: 19158846
    • Birkholz K, Hombach A, Krug C, Reuter S, Kershaw M, Kampgen E, et al. Transfer of mRNA encoding recombinant immunoreceptors reprograms CD4+ and CD8+ T cells for use in the adoptive immunotherapy of cancer. Gene Ther. 2009;16(5):596–604. https://doi.org/10.1038/gt.2008.189.
    • (2009) Gene Ther , vol.16 , Issue.5 , pp. 596-604
    • Birkholz, K.1    Hombach, A.2    Krug, C.3    Reuter, S.4    Kershaw, M.5    Kampgen, E.6
  • 261
    • 77955380678 scopus 로고    scopus 로고
    • Human antigen-specific regulatory T cells generated by T cell receptor gene transfer
    • PID: 20668510
    • Brusko TM, Koya RC, Zhu S, Lee MR, Putnam AL, McClymont SA, et al. Human antigen-specific regulatory T cells generated by T cell receptor gene transfer. PLoS One. 2010;5(7):e11726. https://doi.org/10.1371/journal.pone.0011726.
    • (2010) PLoS One , vol.5 , Issue.7
    • Brusko, T.M.1    Koya, R.C.2    Zhu, S.3    Lee, M.R.4    Putnam, A.L.5    McClymont, S.A.6
  • 262
    • 84862844377 scopus 로고    scopus 로고
    • The battle against immunopathology: infectious tolerance mediated by regulatory T cells
    • COI: 1:CAS:528:DC%2BC38XotlSnu70%3D, PID: 22205213
    • Gravano DM, Vignali DA. The battle against immunopathology: infectious tolerance mediated by regulatory T cells. Cell Mol Life Sci. 2012;69(12):1997–2008. https://doi.org/10.1007/s00018-011-0907-z.
    • (2012) Cell Mol Life Sci , vol.69 , Issue.12 , pp. 1997-2008
    • Gravano, D.M.1    Vignali, D.A.2
  • 263
    • 0036481263 scopus 로고    scopus 로고
    • Epitope spreading in immune-mediated diseases: implications for immunotherapy
    • COI: 1:CAS:528:DC%2BD38XitFSnu7w%3D, PID: 11910899
    • Vanderlugt CL, Miller SD. Epitope spreading in immune-mediated diseases: implications for immunotherapy. Nat Rev Immunol. 2002;2(2):85–95. https://doi.org/10.1038/nri724.
    • (2002) Nat Rev Immunol , vol.2 , Issue.2 , pp. 85-95
    • Vanderlugt, C.L.1    Miller, S.D.2
  • 264
    • 33846681640 scopus 로고    scopus 로고
    • Multi-peptide coupled-cell tolerance ameliorates ongoing relapsing EAE associated with multiple pathogenic autoreactivities
    • COI: 1:CAS:528:DC%2BD2sXhs1ChtLg%3D, PID: 17289470
    • Smith CE, Miller SD. Multi-peptide coupled-cell tolerance ameliorates ongoing relapsing EAE associated with multiple pathogenic autoreactivities. J Autoimmun. 2006;27(4):218–31. https://doi.org/10.1016/j.jaut.2006.12.002.
    • (2006) J Autoimmun , vol.27 , Issue.4 , pp. 218-231
    • Smith, C.E.1    Miller, S.D.2
  • 265
    • 84870953123 scopus 로고    scopus 로고
    • Microparticles bearing encephalitogenic peptides induce T-cell tolerance and ameliorate experimental autoimmune encephalomyelitis
    • COI: 1:CAS:528:DC%2BC38Xhs1ymtLzN, PID: 23159881
    • Getts DR, Martin AJ, McCarthy DP, Terry RL, Hunter ZN, Yap WT, et al. Microparticles bearing encephalitogenic peptides induce T-cell tolerance and ameliorate experimental autoimmune encephalomyelitis. Nat Biotechnol. 2012;30(12):1217–24. https://doi.org/10.1038/nbt.2434.
    • (2012) Nat Biotechnol , vol.30 , Issue.12 , pp. 1217-1224
    • Getts, D.R.1    Martin, A.J.2    McCarthy, D.P.3    Terry, R.L.4    Hunter, Z.N.5    Yap, W.T.6
  • 266
    • 84926433030 scopus 로고    scopus 로고
    • Improving the safety of cell therapy products by suicide gene transfer
    • PID: 25505885
    • Jones BS, Lamb LS, Goldman F, Di Stasi A. Improving the safety of cell therapy products by suicide gene transfer. Front Pharmacol. 2014;5:254. https://doi.org/10.3389/fphar.2014.00254.
    • (2014) Front Pharmacol , vol.5 , pp. 254
    • Jones, B.S.1    Lamb, L.S.2    Goldman, F.3    Di Stasi, A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.