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Volumn 93, Issue 9, 2015, Pages 804-814

Paired TCRαβ analysis of virus-specific CD8+ T cells exposes diversity in a previously defined 'Narrow' repertoire

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; T LYMPHOCYTE RECEPTOR ALPHA CHAIN; T LYMPHOCYTE RECEPTOR BETA CHAIN; COMPLEMENTARITY DETERMINING REGION; LYMPHOCYTE ANTIGEN RECEPTOR;

EID: 84945466038     PISSN: 08189641     EISSN: 14401711     Source Type: Journal    
DOI: 10.1038/icb.2015.44     Document Type: Article
Times cited : (30)

References (71)
  • 1
    • 79952816254 scopus 로고    scopus 로고
    • Bias in the alphabeta t-cell repertoire: Implications for disease pathogenesis and vaccination
    • Miles JJ, Douek DC, Price DA. Bias in the alphabeta T-cell repertoire: implications for disease pathogenesis and vaccination. Immunol Cell Biol 2011; 89: 375-387
    • (2011) Immunol Cell Biol , vol.89 , pp. 375-387
    • Miles, J.J.1    Douek, D.C.2    Price, D.A.3
  • 3
    • 77953195865 scopus 로고    scopus 로고
    • Primary ctl response magnitude in mice is determined by the extent of naive t cell recruitment and subsequent clonal expansion
    • La Gruta NL, Rothwell WT, Cukalac T, Swan NG, Valkenburg SA, Kedzierska K, et al. Primary CTL response magnitude in mice is determined by the extent of naive T cell recruitment and subsequent clonal expansion. J Clin Invest 2010; 120: 1885-1894
    • (2010) J Clin Invest , vol.120 , pp. 1885-1894
    • La Gruta, N.L.1    Rothwell, W.T.2    Cukalac, T.3    Swan, N.G.4    Valkenburg, S.A.5    Kedzierska, K.6
  • 4
    • 34548038390 scopus 로고    scopus 로고
    • Naive cd4(+)frequency varies for different epitopes and predicts repertoire diversity and response magnitude
    • Moon JJ, Chu HH, Pepper M, McSorley SJ, Jameson SC, Kedl RM, et al Naive CD4(+)frequency varies for different epitopes and predicts repertoire diversity and response magnitude. Immunity 2007 27 203-213
    • (2007) Immunity , vol.27 , pp. 203-213
    • Moon, J.J.1    Chu, H.H.2    Pepper, M.3    McSorley, S.J.4    Jameson, S.C.5    Kedl, R.M.6
  • 9
    • 0033557173 scopus 로고    scopus 로고
    • T cell affinity maturation by selective expansion during infection
    • Busch DH, Pamer EG. T cell affinity maturation by selective expansion during infection. J Exp Med 1999; 189: 701-710
    • (1999) J Exp Med , vol.189 , pp. 701-710
    • Busch, D.H.1    Pamer, E.G.2
  • 10
    • 38449105478 scopus 로고    scopus 로고
    • Rapid cd8+ t cell repertoire focusing and selection of high-Affinity clones into memory following primary infection with a persistent human virus: Human cytomegalovirus
    • Day EK, Carmichael AJ, ten Berge IJ, Waller EC, Sissons JG, Wills MR. Rapid CD8+ T cell repertoire focusing and selection of high-Affinity clones into memory following primary infection with a persistent human virus: human cytomegalovirus. J Immunol 2007; 179: 3203-3213
    • (2007) J Immunol , vol.179 , pp. 3203-3213
    • Day, E.K.1    Carmichael, A.J.2    Ten Berge, I.J.3    Waller, E.C.4    Sissons, J.G.5    Wills, M.R.6
  • 11
    • 84885059505 scopus 로고    scopus 로고
    • Interrogating the relationship between naive and immune antiviral t cell repertoires
    • La Gruta NL, Thomas PG. Interrogating the relationship between naive and immune antiviral T cell repertoires. Curr Opin Virol 2013; 3: 447-451
    • (2013) Curr Opin Virol , vol.3 , pp. 447-451
    • La Gruta, N.L.1    Thomas, P.G.2
  • 12
    • 8444236620 scopus 로고    scopus 로고
    • Clonal selection of helper t cells is determined by an affinity threshold with no further skewing of tcr binding properties
    • Malherbe L, Hausl C, Teyton L, McHeyzer-Williams MG. Clonal selection of helper T cells is determined by an affinity threshold with no further skewing of TCR binding properties. Immunity 2004; 21: 669-679
    • (2004) Immunity , vol.21 , pp. 669-679
    • Malherbe, L.1    Hausl, C.2    Teyton, L.3    McHeyzer-Williams, M.G.4
  • 13
    • 27944505610 scopus 로고    scopus 로고
    • Avidity for antigen shapes clonal dominance in cd8+ t cell populations specific for persistent DNA viruses
    • Price DA, Brenchley JM, Ruff LE, Betts MR, Hill BJ, Roederer M, et al. Avidity for antigen shapes clonal dominance in CD8+ T cell populations specific for persistent DNA viruses. J Exp Med 2005; 202: 1349-1361
    • (2005) J Exp Med , vol.202 , pp. 1349-1361
    • Price, D.A.1    Brenchley, J.M.2    Ruff, L.E.3    Betts, M.R.4    Hill, B.J.5    Roederer, M.6
  • 14
    • 0028096713 scopus 로고
    • Dominant selection of an invariant t cell antigen receptor in response to persistent infection by Epstein-Barr virus
    • Argaet VP, Schmidt CW, Burrows SR, Silins SL, Kurilla MG, Doolan DL, et al. Dominant selection of an invariant T cell antigen receptor in response to persistent infection by Epstein-Barr virus. J Exp Med 1994; 180: 2335-2340
    • (1994) J Exp Med , vol.180 , pp. 2335-2340
    • Argaet, V.P.1    Schmidt, C.W.2    Burrows, S.R.3    Silins, S.L.4    Kurilla, M.G.5    Doolan, D.L.6
  • 15
    • 0032528501 scopus 로고    scopus 로고
    • The clonal composition of a peptide-specific oligoclonal ctl repertoire selected in response to persistent ebv infection is stable over time
    • Levitsky V, de Campos-Lima PO, Frisan T, Masucci MG. The clonal composition of a peptide-specific oligoclonal CTL repertoire selected in response to persistent EBV infection is stable over time. J Immunol 1998; 161: 594-601
    • (1998) J Immunol , vol.161 , pp. 594-601
    • Levitsky, V.1    De Campos-Lima, P.O.2    Frisan, T.3    Masucci, M.G.4
  • 17
    • 84866896058 scopus 로고    scopus 로고
    • Deep sequencing of antiviral t-cell responses to hcmv and ebv in humans reveals a stable repertoire that is maintained for many years
    • Klarenbeek PL, Remmerswaal EB, ten Berge IJ, Doorenspleet ME, van Schaik BD, Esveldt RE, et al. Deep sequencing of antiviral T-cell responses to HCMV and EBV in humans reveals a stable repertoire that is maintained for many years. PLoS Pathogen 2012; 8: e1002889
    • (2012) PLoS Pathogen , vol.8 , pp. e1002889
    • Klarenbeek, P.L.1    Remmerswaal, E.B.2    Ten Berge, I.J.3    Doorenspleet, M.E.4    Van Schaik, B.D.5    Esveldt, R.E.6
  • 18
    • 0035500895 scopus 로고    scopus 로고
    • Clonally diverse ctl response to a dominant viral epitope recognizes potential epitope variants
    • Charini WA, Kuroda MJ, Schmitz JE, Beaudry KR, Lin W, Lifton MA, et al. Clonally diverse CTL response to a dominant viral epitope recognizes potential epitope variants. J Immunol 2001; 167: 4996-5003
    • (2001) J Immunol , vol.167 , pp. 4996-5003
    • Charini, W.A.1    Kuroda, M.J.2    Schmitz, J.E.3    Beaudry, K.R.4    Lin, W.5    Lifton, M.A.6
  • 20
    • 77952742298 scopus 로고    scopus 로고
    • Effects of thymic selection of the t-cell repertoire on HLA class i-Associated control of HIV infection
    • Kosmrlj A, Read EL, Qi Y, Allen TM, Altfeld M, Deeks SG, et al. Effects of thymic selection of the T-cell repertoire on HLA class I-Associated control of HIV infection. Nature 2010; 465: 350-354
    • (2010) Nature , vol.465 , pp. 350-354
    • Kosmrlj, A.1    Read, E.L.2    Qi, Y.3    Allen, T.M.4    Altfeld, M.5    Deeks, S.G.6
  • 21
    • 84868143693 scopus 로고    scopus 로고
    • Limited t cell receptor repertoire diversity in tuberculosis patients correlates with clinical severity
    • Luo W, Su J, Zhang XB, Yang Z, Zhou MQ, Jiang ZM, et al. Limited T cell receptor repertoire diversity in tuberculosis patients correlates with clinical severity. PloS ONE 2012; 7: e48117
    • (2012) PloS ONE , vol.7 , pp. e48117
    • Luo, W.1    Su, J.2    Zhang, X.B.3    Yang, Z.4    Zhou, M.Q.5    Jiang, Z.M.6
  • 22
    • 2242419092 scopus 로고    scopus 로고
    • Direct link between MHC polymorphism, t cell avidity, and diversity in immune defense
    • Messaoudi I, Guevara Patino JA, Dyall R, LeMaoult J, Nikolich-Zugich J. Direct link between mhc polymorphism, T cell avidity, and diversity in immune defense. Science 2002; 298: 1797-1800
    • (2002) Science , vol.298 , pp. 1797-1800
    • Messaoudi, I.1    Guevara Patino, J.A.2    Dyall, R.3    LeMaoult, J.4    Nikolich-Zugich, J.5
  • 23
    • 10344231446 scopus 로고    scopus 로고
    • T cell receptor recognition motifs govern immune escape patterns in acute siv infection
    • Price DA, West SM, Betts MR, Ruff LE, Brenchley JM, Ambrozak DR, et al. T cell receptor recognition motifs govern immune escape patterns in acute SIV infection. Immunity 2004; 21: 793-803
    • (2004) Immunity , vol.21 , pp. 793-803
    • Price, D.A.1    West, S.M.2    Betts, M.R.3    Ruff, L.E.4    Brenchley, J.M.5    Ambrozak, D.R.6
  • 24
    • 84859485913 scopus 로고    scopus 로고
    • T cell receptor alphabeta diversity inversely correlates with pathogen-specific antibody levels in human cytomegalovirus infection
    • Wang GC, Dash P, McCullers JA, Doherty PC, Thomas PG. T cell receptor alphabeta diversity inversely correlates with pathogen-specific antibody levels in human cytomegalovirus infection. Sci Transl Med 2012; 4: 128ra42
    • (2012) Sci Transl Med , vol.4 , pp. 128ra42
    • Wang, G.C.1    Dash, P.2    McCullers, J.A.3    Doherty, P.C.4    Thomas, P.G.5
  • 25
    • 84875520974 scopus 로고    scopus 로고
    • A molecular basis for the control of preimmune escape variants by HIV-specific cd8+t cells
    • Ladell K, Hashimoto M, Iglesias MC, Wilmann PG, McLaren JE, Gras S, et al. A molecular basis for the control of preimmune escape variants by HIV-specific CD8+T cells. Immunity 2013; 38: 425-436
    • (2013) Immunity , vol.38 , pp. 425-436
    • Ladell, K.1    Hashimoto, M.2    Iglesias, M.C.3    Wilmann, P.G.4    McLaren, J.E.5    Gras, S.6
  • 26
    • 18344405559 scopus 로고    scopus 로고
    • Two human t cell receptors bind in a similar diagonal mode to the HLA-A2/tax peptide complex using different tcr amino acids
    • Ding YH, Smith KJ, Garboczi DN, Utz U, Biddison WE, Wiley DC. Two human T cell receptors bind in a similar diagonal mode to the HLA-A2/Tax peptide complex using different TCR amino acids. Immunity 1998; 8: 403-411
    • (1998) Immunity , vol.8 , pp. 403-411
    • Ding, Y.H.1    Smith, K.J.2    Garboczi, D.N.3    Utz, U.4    Biddison, W.E.5    Wiley, D.C.6
  • 27
    • 0029855347 scopus 로고    scopus 로고
    • Structure of the complex between human t-cell receptor, viral peptide and HLA-A2
    • Garboczi DN, Ghosh P, Utz U, Fan QR, Biddison WE, Wiley DC. Structure of the complex between human T-cell receptor, viral peptide and HLA-A2. Nature 1996; 384: 134-141
    • (1996) Nature , vol.384 , pp. 134-141
    • Garboczi, D.N.1    Ghosh, P.2    Utz, U.3    Fan, Q.R.4    Biddison, W.E.5    Wiley, D.C.6
  • 28
    • 18344394144 scopus 로고    scopus 로고
    • A t cell receptor cdr3beta loop undergoes conformational changes of unprecedented magnitude upon binding to a peptide/MHC class i complex
    • Reiser JB, Gregoire C, Darnault C, Mosser T, Guimezanes A, Schmitt-Verhulst AM, et al. A T cell receptor CDR3beta loop undergoes conformational changes of unprecedented magnitude upon binding to a peptide/MHC class I complex. Immunity 2002; 16: 345-354
    • (2002) Immunity , vol.16 , pp. 345-354
    • Reiser, J.B.1    Gregoire, C.2    Darnault, C.3    Mosser, T.4    Guimezanes, A.5    Schmitt-Verhulst, A.M.6
  • 31
    • 0037089649 scopus 로고    scopus 로고
    • Predominant role of t cell receptor (tcr)-Alpha chain in forming preimmune tcr repertoire revealed by clonal tcr reconstitution system
    • Yokosuka T, Takase K, Suzuki M, Nakagawa Y, Taki S, Takahashi H, et al. Predominant role of T cell receptor (TCR)-Alpha chain in forming preimmune TCR repertoire revealed by clonal TCR reconstitution system. J Exp Med 2002; 195: 991-1001
    • (2002) J Exp Med , vol.195 , pp. 991-1001
    • Yokosuka, T.1    Takase, K.2    Suzuki, M.3    Nakagawa, Y.4    Taki, S.5    Takahashi, H.6
  • 32
    • 0030443209 scopus 로고    scopus 로고
    • Tcr alpha-chain usage can determine antigenselected tcr beta-chain repertoire diversity
    • Turner SJ, Cose SC, Carbone FR. TCR alpha-chain usage can determine antigenselected TCR beta-chain repertoire diversity. J Immunol 1996; 157: 4979-4985
    • (1996) J Immunol , vol.157 , pp. 4979-4985
    • Turner, S.J.1    Cose, S.C.2    Carbone, F.R.3
  • 33
    • 0033485767 scopus 로고    scopus 로고
    • Antigen-driven selection of tcr in vivo: Related tcr alpha-chains pair with diverse tcr beta-chains
    • Mikszta JA, McHeyzer-Williams LJ, McHeyzer-Williams MG. Antigen-driven selection of TCR in vivo: related TCR alpha-chains pair with diverse TCR beta-chains. J Immunol 1999; 163: 5978-5988
    • (1999) J Immunol , vol.163 , pp. 5978-5988
    • Mikszta, J.A.1    McHeyzer-Williams, L.J.2    McHeyzer-Williams, M.G.3
  • 34
    • 0038082331 scopus 로고    scopus 로고
    • Virus infection expands a biased subset of t cells that bind tetrameric class i peptide complexes
    • Coles RM, Jones CM, Brooks AG, Cameron PU, Heath WR, Carbone FR. Virus infection expands a biased subset of T cells that bind tetrameric class I peptide complexes. Eur J Immunol 2003; 33: 1557-1567
    • (2003) Eur J Immunol , vol.33 , pp. 1557-1567
    • Coles, R.M.1    Jones, C.M.2    Brooks, A.G.3    Cameron, P.U.4    Heath, W.R.5    Carbone, F.R.6
  • 35
    • 33947242311 scopus 로고    scopus 로고
    • Analysis of tcralphabeta combinations used by simian immunodeficiency virus-specific cd8+t cells in rhesus monkeys: Implications for ctl immunodominance
    • Hasegawa A, Moriya C, Liu H, Charini WA, Vinet HC, Subbramanian RA, et al. Analysis of TCRalphabeta combinations used by simian immunodeficiency virus-specific CD8+T cells in rhesus monkeys: implications for CTL immunodominance. J Immunol 2007; 178: 3409-3417
    • (2007) J Immunol , vol.178 , pp. 3409-3417
    • Hasegawa, A.1    Moriya, C.2    Liu, H.3    Charini, W.A.4    Vinet, H.C.5    Subbramanian, R.A.6
  • 36
    • 77950541195 scopus 로고    scopus 로고
    • Comprehensive assessment of t-cell receptor beta-chain diversity in alphabeta t cells
    • Robins HS, Campregher PV, Srivastava SK, Wacher A, Turtle CJ, Kahsai O, et al. Comprehensive assessment of T-cell receptor beta-chain diversity in alphabeta T cells. Blood 2009; 114: 4099-4107
    • (2009) Blood , vol.114 , pp. 4099-4107
    • Robins, H.S.1    Campregher, P.V.2    Srivastava, S.K.3    Wacher, A.4    Turtle, C.J.5    Kahsai, O.6
  • 37
    • 76549090763 scopus 로고    scopus 로고
    • High throughput sequencing reveals a complex pattern of dynamic interrelationships among human t cell subsets
    • Wang C, Sanders CM, Yang Q, Schroeder HW Jr., Wang E, Babrzadeh F, et al. High throughput sequencing reveals a complex pattern of dynamic interrelationships among human T cell subsets. Proc Natl Acad Sci USA 2010; 107: 1518-1523
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 1518-1523
    • Wang, C.1    Sanders, C.M.2    Yang, Q.3    Schroeder, H.W.4    Wang, E.5    Babrzadeh, F.6
  • 38
    • 78650937547 scopus 로고    scopus 로고
    • Paired analysis of tcralpha and tcrbeta chains at the single-cell level in mice
    • Dash P, McClaren JL, Oguin TH 3rd, Rothwell W, Todd B, Morris MY, et al. Paired analysis of TCRalpha and TCRbeta chains at the single-cell level in mice. J Clin Invest 2011; 121: 288-295
    • (2011) J Clin Invest , vol.121 , pp. 288-295
    • Dash, P.1    McClaren, J.L.2    Oguin, T.H.3    Rothwell, W.4    Todd, B.5    Morris, M.Y.6
  • 40
    • 38649139095 scopus 로고    scopus 로고
    • Comprehensive analysis of the functional tcr repertoire at the single-cell level
    • Ozawa T, Tajiri K, Kishi H, Muraguchi A. Comprehensive analysis of the functional TCR repertoire at the single-cell level. Biochem Biophys Res Commun 2008; 367: 820-825
    • (2008) Biochem Biophys Res Commun , vol.367 , pp. 820-825
    • Ozawa, T.1    Tajiri, K.2    Kishi, H.3    Muraguchi, A.4
  • 41
    • 84863649147 scopus 로고    scopus 로고
    • Unbiased analysis of tcralpha/beta chains at the single-cell level in human cd8+ t-cell subsets
    • Sun X, Saito M, Sato Y, Chikata T, Naruto T, Ozawa T, et al. Unbiased analysis of TCRalpha/beta chains at the single-cell level in human CD8+ T-cell subsets. PloS ONE 2012; 7: e40386
    • (2012) PloS ONE , vol.7 , pp. e40386
    • Sun, X.1    Saito, M.2    Sato, Y.3    Chikata, T.4    Naruto, T.5    Ozawa, T.6
  • 42
    • 84887445200 scopus 로고    scopus 로고
    • A new cloning and expression system yields and validates tcrs from blood lymphocytes of patients with cancer within 10 days
    • Kobayashi E, Mizukoshi E, Kishi H, Ozawa T, Hamana H, Nagai T, et al. A new cloning and expression system yields and validates TCRs from blood lymphocytes of patients with cancer within 10 days. Nat Med 2013; 19: 1542-1546
    • (2013) Nat Med , vol.19 , pp. 1542-1546
    • Kobayashi, E.1    Mizukoshi, E.2    Kishi, H.3    Ozawa, T.4    Hamana, H.5    Nagai, T.6
  • 43
    • 0027163489 scopus 로고
    • Prominent usage of v beta 8.3 t cells in the h-2db-restricted response to an influenza a virus nucleoprotein epitope
    • Deckhut AM, Allan W, McMickle A, Eichelberger M, Blackman MA, Doherty PC, et al. Prominent usage of V beta 8.3 T cells in the H-2Db-restricted response to an influenza A virus nucleoprotein epitope. J Immunol 1993; 151: 2658-2666
    • (1993) J Immunol , vol.151 , pp. 2658-2666
    • Deckhut, A.M.1    Allan, W.2    McMickle, A.3    Eichelberger, M.4    Blackman, M.A.5    Doherty, P.C.6
  • 44
    • 41149084984 scopus 로고    scopus 로고
    • Epitopespecific tcrbeta repertoire diversity imparts no functional advantage on the cd8+ t cell response to cognate viral peptides
    • La Gruta NL, Thomas PG, Webb AI, Dunstone MA, Cukalac T, Doherty PC, et al. Epitopespecific TCRbeta repertoire diversity imparts no functional advantage on the CD8+ T cell response to cognate viral peptides. Proc Natl Acad Sci USA 2008; 105: 2034-2039
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 2034-2039
    • La Gruta, N.L.1    Thomas, P.G.2    Webb, A.I.3    Dunstone, M.A.4    Cukalac, T.5    Doherty, P.C.6
  • 45
    • 0034283930 scopus 로고    scopus 로고
    • Contemporary analysis of MHC-related immunodominance hierarchies in the cd8+ t cell response to influenza a viruses
    • Belz GT, Stevenson PG, Doherty PC. Contemporary analysis of MHC-related immunodominance hierarchies in the CD8+ T cell response to influenza A viruses. J Immunol 2000; 165: 2404-2409
    • (2000) J Immunol , vol.165 , pp. 2404-2409
    • Belz, G.T.1    Stevenson, P.G.2    Doherty, P.C.3
  • 46
    • 0037399343 scopus 로고    scopus 로고
    • Analysis of clonotype distribution and persistence for an influenza virus-specific cd8+ t cell response
    • Turner SJ, Diaz G, Cross R, Doherty PC. Analysis of clonotype distribution and persistence for an influenza virus-specific CD8+ T cell response. Immunity 2003; 18: 549-559
    • (2003) Immunity , vol.18 , pp. 549-559
    • Turner, S.J.1    Diaz, G.2    Cross, R.3    Doherty, P.C.4
  • 47
    • 1842687400 scopus 로고    scopus 로고
    • Conserved t cell receptor usage in primary and recall responses to an immunodominant influenza virus nucleoprotein epitope
    • Kedzierska K, Turner SJ, Doherty PC. Conserved T cell receptor usage in primary and recall responses to an immunodominant influenza virus nucleoprotein epitope. Proc Natl Acad Sci USA 2004; 101: 4942-4947
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 4942-4947
    • Kedzierska, K.1    Turner, S.J.2    Doherty, P.C.3
  • 48
    • 8344272118 scopus 로고    scopus 로고
    • In vivo selection of a tcr vbeta repertoire directed against an immunodominant influenza virus ctl epitope
    • Zhong W, Reinherz EL. In vivo selection of a TCR Vbeta repertoire directed against an immunodominant influenza virus CTL epitope. Int Immunol 2004; 16: 1549-1559
    • (2004) Int Immunol , vol.16 , pp. 1549-1559
    • Zhong, W.1    Reinherz, E.L.2
  • 49
    • 84873184482 scopus 로고    scopus 로고
    • Ecological analysis of antigen-specific ctl repertoires defines the relationship between naive and immune t-cell populations
    • Thomas PG, Handel A, Doherty PC, La Gruta NL. Ecological analysis of antigen-specific CTL repertoires defines the relationship between naive and immune T-cell populations. Proc Natl Acad Sci USA 2013; 110: 1839-1844
    • (2013) Proc Natl Acad Sci USA , vol.110 , pp. 1839-1844
    • Thomas, P.G.1    Handel, A.2    Doherty, P.C.3    La Gruta, N.L.4
  • 50
    • 34547941090 scopus 로고    scopus 로고
    • Ctl recognition of a protective immunodominant influenza a virus nucleoprotein epitope utilizes a highly restricted vbeta but diverse valpha repertoire: Functional and structural implications
    • Zhong W, Dixit SB, Mallis RJ, Arthanari H, Lugovskoy AA, Beveridge DL, et al. CTL recognition of a protective immunodominant influenza A virus nucleoprotein epitope utilizes a highly restricted Vbeta but diverse Valpha repertoire: functional and structural implications. J Mol Biol 2007; 372: 535-548
    • (2007) J Mol Biol , vol.372 , pp. 535-548
    • Zhong, W.1    Dixit, S.B.2    Mallis, R.J.3    Arthanari, H.4    Lugovskoy, A.A.5    Beveridge, D.L.6
  • 54
    • 0028169415 scopus 로고
    • Public and private v beta t cell receptor repertoires against hen egg white lysozyme (hel) in nontransgenic versus hel transgenic mice
    • Cibotti R, Cabaniols JP, Pannetier C, Delarbre C, Vergnon I, Kanellopoulos JM, et al. Public and private V beta T cell receptor repertoires against hen egg white lysozyme (HEL) in nontransgenic versus HEL transgenic mice. J Exp Med 1994; 180: 861-872
    • (1994) J Exp Med , vol.180 , pp. 861-872
    • Cibotti, R.1    Cabaniols, J.P.2    Pannetier, C.3    Delarbre, C.4    Vergnon, I.5    Kanellopoulos, J.M.6
  • 55
    • 84921488845 scopus 로고    scopus 로고
    • Fixed expression of single influenza virus-specific tcr chains demonstrates the capacity for tcr alpha- and beta-chain diversity in the face of peptide-MHC class i specificity
    • Clemens EB, Doherty PC, La Gruta NL, Turner SJ. Fixed expression of single influenza virus-specific TCR chains demonstrates the capacity for TCR alpha- and beta-chain diversity in the face of peptide-MHC class I specificity. J Immunol 2015; 194: 898-910
    • (2015) J Immunol , vol.194 , pp. 898-910
    • Clemens, E.B.1    Doherty, P.C.2    La Gruta, N.L.3    Turner, S.J.4
  • 57
    • 20144386628 scopus 로고    scopus 로고
    • Lack of prominent peptide-major histocompatibility complex features limits repertoire diversity in virus-specific cd8+ t cell populations
    • Turner SJ, Kedzierska K, Komodromou H, La Gruta NL, Dunstone MA, Webb AI, et al. Lack of prominent peptide-major histocompatibility complex features limits repertoire diversity in virus-specific CD8+ T cell populations. Nat Immunol 2005; 6: 382-389
    • (2005) Nat Immunol , vol.6 , pp. 382-389
    • Turner, S.J.1    Kedzierska, K.2    Komodromou, H.3    La Gruta, N.L.4    Dunstone, M.A.5    Webb, A.I.6
  • 58
    • 84889240444 scopus 로고    scopus 로고
    • Acute emergence and reversion of influenza a virus quasispecies within cd8+ t cell antigenic peptides
    • Valkenburg SA, Quinones-Parra S, Gras S, Komadina N, McVernon J, Wang Z, et al. Acute emergence and reversion of influenza A virus quasispecies within CD8+ T cell antigenic peptides. Nat Commun 2013; 4: 2663
    • (2013) Nat Commun , vol.4 , pp. 2663
    • Valkenburg, S.A.1    Quinones-Parra, S.2    Gras, S.3    Komadina, N.4    McVernon, J.5    Wang, Z.6
  • 59
    • 19944427950 scopus 로고    scopus 로고
    • HIV-specific cytotoxic t cells from long-Term survivors select a unique t cell receptor
    • Dong T, Stewart-Jones G, Chen N, Easterbrook P, Xu X, Papagno L, et al. HIV-specific cytotoxic T cells from long-Term survivors select a unique T cell receptor. J Exp Med 2004; 200: 1547-1557
    • (2004) J Exp Med , vol.200 , pp. 1547-1557
    • Dong, T.1    Stewart-Jones, G.2    Chen, N.3    Easterbrook, P.4    Xu, X.5    Papagno, L.6
  • 60
    • 33748581671 scopus 로고    scopus 로고
    • Strong tcr conservation and altered t cell cross-reactivity characterize a b57-restricted immune response in HIV-1 infection
    • Gillespie GM, Stewart-Jones G, Rengasamy J, Beattie T, Bwayo JJ, Plummer FA, et al. Strong TCR conservation and altered T cell cross-reactivity characterize a B57-restricted immune response in HIV-1 infection. J Immunol 2006; 177: 3893-3902
    • (2006) J Immunol , vol.177 , pp. 3893-3902
    • Gillespie, G.M.1    Stewart-Jones, G.2    Rengasamy, J.3    Beattie, T.4    Bwayo, J.J.5    Plummer, F.A.6
  • 61
    • 33846813973 scopus 로고    scopus 로고
    • Mutually exclusive t-cell receptor induction and differential susceptibility to human immunodeficiency virus type 1 mutational escape associated with a two-Amino-Acid difference between HLA class i subtypes
    • Yu XG, Lichterfeld M, Chetty S, Williams KL, Mui SK, Miura T, et al. Mutually exclusive T-cell receptor induction and differential susceptibility to human immunodeficiency virus type 1 mutational escape associated with a two-Amino-Acid difference between HLA class I subtypes. J Virol 2007; 81: 1619-1631
    • (2007) J Virol , vol.81 , pp. 1619-1631
    • Yu, X.G.1    Lichterfeld, M.2    Chetty, S.3    Williams, K.L.4    Mui, S.K.5    Miura, T.6
  • 62
    • 79251590221 scopus 로고    scopus 로고
    • Persistent survival of prevalent clonotypes within an immunodominant HIV gag-specific cd8+ t cell response
    • van Bockel DJ, Price DA, Munier ML, Venturi V, Asher TE, Ladell K, et al. Persistent survival of prevalent clonotypes within an immunodominant HIV gag-specific CD8+ T cell response. J Immunol 2011; 186: 359-371
    • (2011) J Immunol , vol.186 , pp. 359-371
    • Van Bockel, D.J.1    Price, D.A.2    Munier, M.L.3    Venturi, V.4    Asher, T.E.5    Ladell, K.6
  • 63
    • 84862621390 scopus 로고    scopus 로고
    • Tcr clonotypes modulate the protective effect of HLA class i molecules in HIV-1 infection
    • Chen H, Ndhlovu ZM, Liu D, Porter LC, Fang JW, Darko S, et al. TCR clonotypes modulate the protective effect of HLA class I molecules in HIV-1 infection. Nat Immunol 2012; 13: 691-700
    • (2012) Nat Immunol , vol.13 , pp. 691-700
    • Chen, H.1    Ndhlovu, Z.M.2    Liu, D.3    Porter, L.C.4    Fang, J.W.5    Darko, S.6
  • 64
    • 0035253434 scopus 로고    scopus 로고
    • High-Avidity ctl exploit two complementary mechanisms to provide better protection against viral infection than low-Avidity ctl
    • Derby M, Alexander-Miller M, Tse R, Berzofsky J. High-Avidity CTL exploit two complementary mechanisms to provide better protection against viral infection than low-Avidity CTL. J Immunol 2001; 166: 1690-1697
    • (2001) J Immunol , vol.166 , pp. 1690-1697
    • Derby, M.1    Alexander-Miller, M.2    Tse, R.3    Berzofsky, J.4
  • 65
    • 1542513761 scopus 로고    scopus 로고
    • Differential tumor necrosis factor receptor 2-mediated editing of virus-specific cd8+ effector t cells
    • Turner SJ, La Gruta NL, Stambas J, Diaz G, Doherty PC. Differential tumor necrosis factor receptor 2-mediated editing of virus-specific CD8+ effector T cells. Proc Natl Acad Sci USA 2004; 101: 3545-3550
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 3545-3550
    • Turner, S.J.1    La Gruta, N.L.2    Stambas, J.3    Diaz, G.4    Doherty, P.C.5
  • 66
    • 33751224154 scopus 로고    scopus 로고
    • A correlation between function and selected measures of t cell avidity in influenza virus-specific cd8+ t cell responses
    • La Gruta NL, Doherty PC, Turner SJ. A correlation between function and selected measures of T cell avidity in influenza virus-specific CD8+ T cell responses. Eur J Immunol 2006; 36: 2951-2959
    • (2006) Eur J Immunol , vol.36 , pp. 2951-2959
    • La Gruta, N.L.1    Doherty, P.C.2    Turner, S.J.3
  • 67
    • 2142815852 scopus 로고    scopus 로고
    • Hierarchies in cytokine expression profiles for acute and resolving influenza virus-specific cd8+ t cell responses: Correlation of cytokine profile and tcr avidity
    • La Gruta NL, Turner SJ, Doherty PC. Hierarchies in cytokine expression profiles for acute and resolving influenza virus-specific CD8+ T cell responses: correlation of cytokine profile and TCR avidity. J Immunol 2004; 172: 5553-5560
    • (2004) J Immunol , vol.172 , pp. 5553-5560
    • La Gruta, N.L.1    Turner, S.J.2    Doherty, P.C.3
  • 68
    • 79959353928 scopus 로고    scopus 로고
    • Structural basis for enabling t-cell receptor diversity within biased virus-specific cd8+ t-cell responses
    • Day EB, Guillonneau C, Gras S, La Gruta NL, Vignali DA, Doherty PC, et al. Structural basis for enabling T-cell receptor diversity within biased virus-specific CD8+ T-cell responses. Proc Natl Acad Sci USA 2011; 108: 9536-9541
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 9536-9541
    • Day, E.B.1    Guillonneau, C.2    Gras, S.3    La Gruta, N.L.4    Vignali, D.A.5    Doherty, P.C.6
  • 69
    • 44649127931 scopus 로고    scopus 로고
    • Endogenous naive cd8+ t cell precursor frequency regulates primary and memory responses to infection
    • Obar JJ, Khanna KM, Lefrancois L. Endogenous naive CD8+ T cell precursor frequency regulates primary and memory responses to infection. Immunity 2008; 28: 859-869
    • (2008) Immunity , vol.28 , pp. 859-869
    • Obar, J.J.1    Khanna, K.M.2    Lefrancois, L.3
  • 70
    • 0035166917 scopus 로고    scopus 로고
    • Imgt, the international immunogenetics database
    • Lefranc MP. IMGT, the International ImMunoGeneTics database. Nucleic Acids Res 2001; 29: 207-209
    • (2001) Nucleic Acids Res , vol.29 , pp. 207-209
    • Lefranc, M.P.1
  • 71
    • 53149138983 scopus 로고    scopus 로고
    • Terminal deoxynucleotidyltransferase is required for the establishment of private virusspecific cd8+ tcr repertoires and facilitates optimal ctl responses
    • Kedzierska K, Thomas PG, Venturi V, Davenport MP, Doherty PC, Turner SJ, et al. Terminal deoxynucleotidyltransferase is required for the establishment of private virusspecific CD8+ TCR repertoires and facilitates optimal CTL responses. J Immunol 2008; 181: 2556-2562
    • (2008) J Immunol , vol.181 , pp. 2556-2562
    • Kedzierska, K.1    Thomas, P.G.2    Venturi, V.3    Davenport, M.P.4    Doherty, P.C.5    Turner, S.J.6


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