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Volumn 2, Issue 10, 2001, Pages 962-970

Circumventing tolerance to a human MDM2-derived tumor antigen by TCR gene transfer

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; HLA A2 ANTIGEN; MURINE DOUBLE MINUTE ONCOPROTEIN 2; ONCOPROTEIN; T LYMPHOCYTE RECEPTOR ALPHA CHAIN; T LYMPHOCYTE RECEPTOR BETA CHAIN; TUMOR ANTIGEN; UNCLASSIFIED DRUG; VIRUS VECTOR;

EID: 0034780027     PISSN: 15292908     EISSN: None     Source Type: Journal    
DOI: 10.1038/ni1001-962     Document Type: Article
Times cited : (326)

References (44)
  • 1
    • 0033103021 scopus 로고    scopus 로고
    • A new era for cancer immunotherapy based on the genes that encode cancer antigens
    • (1999) Immunity , vol.10 , pp. 281-287
    • Rosenberg, S.A.1
  • 6
    • 0030892137 scopus 로고    scopus 로고
    • Tolerance to p53 by A2.1-restricted cytotoxic T lymphocytes
    • (1997) J. Exp. Med. , vol.185 , pp. 833-841
    • Theobald, M.1
  • 11
    • 0027980319 scopus 로고
    • Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules
    • (1994) Cell , vol.78 , pp. 761-771
    • Rock, K.L.1
  • 12
    • 0033521621 scopus 로고    scopus 로고
    • ARF with Mdm2 inhibits ubiquitin ligase activity of Mdm2 for tumor suppressor p53
    • (1999) EMBO J. , vol.18 , pp. 22-27
    • Honda, R.1    Yasuda, H.2
  • 22
    • 0030602834 scopus 로고    scopus 로고
    • Coordinated dual cleavages induced by the proteasome regulator PA28 lead to dominant MHC ligands
    • (1996) Cell , vol.86 , pp. 253-262
    • Dick, T.P.1
  • 23
    • 0033980648 scopus 로고    scopus 로고
    • Processing of some antigens by the standard proteasome but not by the immunoproteasome results in poor presentation by dendritic cells
    • (2000) Immunity , vol.12 , pp. 107-117
    • Morel, S.1
  • 24
    • 0034614889 scopus 로고    scopus 로고
    • Efficient generation of a hepatitis B virus cytotoxic T lymphocyte epitope requires the structural features of immunoproteasomes
    • (2000) J. Exp. Med. , vol.191 , pp. 503-514
    • Sijts, A.J.A.M.1
  • 26
    • 0030806085 scopus 로고    scopus 로고
    • In thymic selection, peptide diversity gives and takes away
    • (1997) Immunity , vol.7 , pp. 175-178
    • Bevan, M.J.1
  • 27
    • 0033105695 scopus 로고    scopus 로고
    • +T cells resulting in a failure to lyse tumor cells
    • (1999) Blood , vol.93 , pp. 1634-1642
    • Steinbrink, K.1
  • 33
    • 0033168142 scopus 로고    scopus 로고
    • Efficient transfer of a tumor antigen-reactive TCR to human peripheral blood lymphocytes confers anti-tumor reactivity
    • (1999) J. Immunol. , vol.163 , pp. 507-513
    • Clay, T.M.1
  • 34
    • 0033849524 scopus 로고    scopus 로고
    • Grafting primary human T lymphocytes with cancer-specific chimeric single chain and two chain TCR
    • (2000) Gene Ther. , vol.7 , pp. 1369-1377
    • Willemsen, R.A.1
  • 39
    • 0028134881 scopus 로고
    • A general method for facilitating heterodimeric pairing between two proteins: Application to expression of α and β T-cell receptor extracellular elements
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 11408-11412
    • Chang, H.-C.1
  • 42
    • 2642631750 scopus 로고    scopus 로고
    • Pro-inflammatory cytokines and prostaglandins induce maturation of potent immunostimulatory dendritic cells under fetal calf serum-free conditions
    • (1997) Eur. J. Immunol. , vol.27 , pp. 3135-3142
    • Jonuleit, H.1
  • 43
    • 0033215226 scopus 로고    scopus 로고
    • Modified vaccinia virus ankara for delivery of human tyrosinase as melanoma-associated antigen: Induction of tyrosinase- and melanoma-specific human leukocyte antigen A*0201-restricted cytotoxic T cells in vitro and in vivo
    • (1999) Cancer Res. , vol.59 , pp. 4955-4963
    • Drexler, I.1
  • 44
    • 0032555911 scopus 로고    scopus 로고
    • The sequence alteration associated with a mutational hotspot in p53 protects cells from lysis by cytotoxic T lymphocytes specific for a flanking peptide epitope
    • (1998) J. Exp. Med. , vol.188 , pp. 1017-1028
    • Theobald, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.