High diversity in the TCR repertoire of GAD65 autoantigen-specific human CD4+ T cells

Journal of Immunology

Volumn 194, Issue 6, 2015, Pages 2531-2538

  Eugster, Anne ^a   Lindner, Annett ^a   Catani, Mara ^a   Heninger, Anne Kristin ^a   Dahl, Andreas ^b   Klemroth, Sylvia ^b   Kuhn, Denise ^a   Dietz, Sevina ^a   Bickle, Marc ^c   Ziegler, Anette Gabrielle ^d,e   Bonifacio, Ezio ^a,d,f  

^a CENTER FOR REGENERATIVE THERAPIES DRESDEN   (Germany)

^b DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

^c MAX PLANCK INSTITUTE OF MOLECULAR CELL BIOLOGY AND GENETICS   (Germany)

^d INSTITUTE OF EPIDEMIOLOGY   (Germany)

^e TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^f DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; AUTOANTIGEN; CD45RA ANTIGEN; GLUTAMATE DECARBOXYLASE 65; HLA DRB1 ANTIGEN; T LYMPHOCYTE RECEPTOR; T LYMPHOCYTE RECEPTOR ALPHA CHAIN; T LYMPHOCYTE RECEPTOR BETA CHAIN; COMPLEMENTARITY DETERMINING REGION; GLUTAMATE DECARBOXYLASE; GLUTAMATE DECARBOXYLASE 1; LYMPHOCYTE ANTIGEN RECEPTOR; PANCREAS ISLET CELL ANTIBODY;

ADOLESCENT; ADULT; ANTIGEN SPECIFICITY; ARTICLE; CD4+ T LYMPHOCYTE; CELL ISOLATION; CELL PROLIFERATION; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; FLUORESCENCE ACTIVATED CELL SORTING; GENE; HUMAN; HUMAN CELL; IMMUNOREACTIVITY; INNATE IMMUNITY; INSULIN DEPENDENT DIABETES MELLITUS; MALE; NEXT GENERATION SEQUENCING; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRAV GENE; TRBV GENE; COMPLEMENTARITY DETERMINING REGION; GENETIC VARIABILITY; GENETICS; HIGH THROUGHPUT SEQUENCING; IMMUNOLOGY; IMPAIRED GLUCOSE TOLERANCE; INFANT; METABOLISM; PRESCHOOL CHILD; PROCEDURES; SINGLE CELL ANALYSIS; YOUNG ADULT;

ADOLESCENT; ADULT; AUTOANTIBODIES; AUTOANTIGENS; CD4-POSITIVE T-LYMPHOCYTES; CHILD, PRESCHOOL; COMPLEMENTARITY DETERMINING REGIONS; DIABETES MELLITUS, TYPE 1; FEMALE; GENETIC VARIATION; GLUTAMATE DECARBOXYLASE; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; INFANT; MALE; PREDIABETIC STATE; RECEPTORS, ANTIGEN, T-CELL; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; SINGLE-CELL ANALYSIS; YOUNG ADULT;

EID: 84924610426     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1403031     Document Type: Article

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