-
1
-
-
15244341417
-
A viral epitope that mimics a self antigen can accelerate but not initiate autoimmune diabetes
-
Christen, U., K.H. Edelmann, D.B. McGavern, T. Wolfe, B. Coon, M.K. Teague, S.D. Miller, M.B. Oldstone, and M.G. von Herrath. 2004. A viral epitope that mimics a self antigen can accelerate but not initiate autoimmune diabetes. J. Clin. Invest. 114:1290-1298.
-
(2004)
J. Clin. Invest.
, vol.114
, pp. 1290-1298
-
-
Christen, U.1
Edelmann, K.H.2
McGavern, D.B.3
Wolfe, T.4
Coon, B.5
Teague, M.K.6
Miller, S.D.7
Oldstone, M.B.8
von Herrath, M.G.9
-
2
-
-
70349656802
-
Histopathology of type 1 diabetes: old paradigms and new insights
-
Coppieters, K.T., and M.G. von Herrath. 2009. Histopathology of type 1 diabetes: old paradigms and new insights. Rev. Diabet. Stud. 6:85-96. http://dx.doi.org/10.1900/RDS.2009.6.85
-
(2009)
Rev. Diabet. Stud.
, vol.6
, pp. 85-96
-
-
Coppieters, K.T.1
von Herrath, M.G.2
-
3
-
-
64749084427
-
C-peptide levels and insulin independence following autologous nonmyeloablative hematopoietic stem cell transplantation in newly diagnosed type 1 diabetes mellitus
-
Couri, C.E., M.C. Oliveira, A.B. Stracieri, D.A. Moraes, F. Pieroni, G.M. Barros, M.I. Madeira, K.C. Malmegrim, M.C. Foss-Freitas, B.P. Simões, et al. 2009. C-peptide levels and insulin independence following autologous nonmyeloablative hematopoietic stem cell transplantation in newly diagnosed type 1 diabetes mellitus. JAMA. 301:1573-1579. http://dx.doi.org/10.1001/jama.2009.470
-
(2009)
JAMA
, vol.301
, pp. 1573-1579
-
-
Couri, C.E.1
Oliveira, M.C.2
Stracieri, A.B.3
Moraes, D.A.4
Pieroni, F.5
Barros, G.M.6
Madeira, M.I.7
Malmegrim, K.C.8
Foss-Freitas, M.C.9
Simões, B.P.10
-
4
-
-
77951169178
-
Banting Lecture 2009: An unfinished journey: molecular pathogenesis to prevention of type 1A diabetes
-
Eisenbarth, G.S. 2010. Banting Lecture 2009: An unfinished journey: molecular pathogenesis to prevention of type 1A diabetes. Diabetes. 59:759-774. http://dx.doi.org/10.2337/db09-1855
-
(2010)
Diabetes
, vol.59
, pp. 759-774
-
-
Eisenbarth, G.S.1
-
5
-
-
45949111885
-
Equivalent specificity of peripheral blood and islet-infiltrating CD8+ T lymphocytes in spontaneously diabetic HLA-A2 transgenic NOD mice
-
Enée, E., E. Martinuzzi, P. Blancou, J.M. Bach, R. Mallone, and P. van Endert. 2008. Equivalent specificity of peripheral blood and islet-infiltrating CD8+ T lymphocytes in spontaneously diabetic HLA-A2 transgenic NOD mice. J. Immunol. 180:5430-5438.
-
(2008)
J. Immunol.
, vol.180
, pp. 5430-5438
-
-
Enée, E.1
Martinuzzi, E.2
Blancou, P.3
Bach, J.M.4
Mallone, R.5
van Endert, P.6
-
6
-
-
0022475906
-
The histopathology of the pancreas in type 1 (insulindependent) diabetes mellitus: a 25-year review of deaths in patients under 20 years of age in the United Kingdom
-
Foulis, A.K., C.N. Liddle, M.A. Farquharson, J.A. Richmond, and R.S. Weir. 1986. The histopathology of the pancreas in type 1 (insulindependent) diabetes mellitus: a 25-year review of deaths in patients under 20 years of age in the United Kingdom. Diabetologia. 29:267-274. http://dx.doi.org/10.1007/BF00452061
-
(1986)
Diabetologia
, vol.29
, pp. 267-274
-
-
Foulis, A.K.1
Liddle, C.N.2
Farquharson, M.A.3
Richmond, J.A.4
Weir, R.S.5
-
7
-
-
0023520177
-
Immunoreactive alphainterferon in insulin-secreting beta cells in type 1 diabetes mellitus
-
Foulis, A.K., M.A. Farquharson, and A. Meager. 1987. Immunoreactive alphainterferon in insulin-secreting beta cells in type 1 diabetes mellitus. Lancet. 2:1423-1427. http://dx.doi.org/10.1016/S0140-6736(87)91128-7
-
(1987)
Lancet
, vol.2
, pp. 1423-1427
-
-
Foulis, A.K.1
Farquharson, M.A.2
Meager, A.3
-
8
-
-
77955549725
-
Subcutaneous insulin B:9-23/IFA immunisation induces Tregs that control late-stage prediabetes in NOD mice through IL-10 and IFNgamma
-
Fousteri, G., A. Dave, A. Bot, T. Juntti, S. Omid, and M. von Herrath. 2010. Subcutaneous insulin B:9-23/IFA immunisation induces Tregs that control late-stage prediabetes in NOD mice through IL-10 and IFNgamma. Diabetologia. 53:1958-1970. http://dx.doi.org/10.1007/s00125-010-1777-x
-
(2010)
Diabetologia
, vol.53
, pp. 1958-1970
-
-
Fousteri, G.1
Dave, A.2
Bot, A.3
Juntti, T.4
Omid, S.5
von Herrath, M.6
-
9
-
-
76549198972
-
Pathologic anatomy of the pancreas in juvenile diabetes mellitus
-
Gepts, W. 1965. Pathologic anatomy of the pancreas in juvenile diabetes mellitus. Diabetes. 14:619-633.
-
(1965)
Diabetes
, vol.14
, pp. 619-633
-
-
Gepts, W.1
-
10
-
-
77949267089
-
Dimorphic histopathology of long-standing childhood-onset diabetes
-
Gianani, R., M. Campbell-Thompson, S.A. Sarkar, C. Wasserfall, A. Pugliese, J.M. Solis, S.C. Kent, B.J. Hering, E. West, A. Steck, et al. 2010. Dimorphic histopathology of long-standing childhood-onset diabetes. Diabetologia. 53:690-698. http://dx.doi.org/10.1007/s00125-009-1642-y
-
(2010)
Diabetologia
, vol.53
, pp. 690-698
-
-
Gianani, R.1
Campbell-Thompson, M.2
Sarkar, S.A.3
Wasserfall, C.4
Pugliese, A.5
Solis, J.M.6
Kent, S.C.7
Hering, B.J.8
West, E.9
Steck, A.10
-
11
-
-
34548397755
-
Screening for insulitis in adult autoantibody-positive organ donors
-
In't Veld, P., D. Lievens, J. De Grijse, Z. Ling, B. Van der Auwera, M. Pipeleers-Marichal, F. Gorus, and D. Pipeleers. 2007. Screening for insulitis in adult autoantibody-positive organ donors. Diabetes. 56:2400-2404. http://dx.doi.org/10.2337/db07-0416
-
(2007)
Diabetes
, vol.56
, pp. 2400-2404
-
-
In't Veld, P.1
Lievens, D.2
De Grijse, J.3
Ling, Z.4
Van der Auwera, B.5
Pipeleers-Marichal, M.6
Gorus, F.7
Pipeleers, D.8
-
12
-
-
78049320362
-
Residual insulin production and pancreatic ß-cell turnover after 50 years of diabetes: Joslin Medalist Study
-
Keenan, H.A., J.K. Sun, J. Levine, A. Doria, L.P. Aiello, G. Eisenbarth, S. Bonner-Weir, and G.L. King. 2010. Residual insulin production and pancreatic ß-cell turnover after 50 years of diabetes: Joslin Medalist Study. Diabetes. 59:2846-2853. http://dx.doi.org/10.2337/db10-0676
-
(2010)
Diabetes
, vol.59
, pp. 2846-2853
-
-
Keenan, H.A.1
Sun, J.K.2
Levine, J.3
Doria, A.4
Aiello, L.P.5
Eisenbarth, G.6
Bonner-Weir, S.7
King, G.L.8
-
13
-
-
0027166935
-
Determinant spreading and the dynamics of the autoimmune T-cell repertoire
-
Lehmann, P.V., E.E. Sercarz, T. Forsthuber, C.M. Dayan, and G. Gammon. 1993. Determinant spreading and the dynamics of the autoimmune T-cell repertoire. Immunol. Today. 14:203-208. http://dx.doi.org/10.1016/0167-5699(93)90163-F
-
(1993)
Immunol. Today.
, vol.14
, pp. 203-208
-
-
Lehmann, P.V.1
Sercarz, E.E.2
Forsthuber, T.3
Dayan, C.M.4
Gammon, G.5
-
14
-
-
0037478632
-
Identification of the beta cell antigen targeted by a prevalent population of pathogenic CD8+ T cells in autoimmune diabetes
-
Lieberman, S.M., A.M. Evans, B. Han, T. Takaki, Y. Vinnitskaya, J.A. Caldwell, D.V. Serreze, J. Shabanowitz, D.F. Hunt, S.G. Nathenson, et al. 2003. Identification of the beta cell antigen targeted by a prevalent population of pathogenic CD8+ T cells in autoimmune diabetes. Proc. Natl. Acad. Sci. USA. 100:8384-8388. http://dx.doi.org/10.1073/pnas.0932778100
-
(2003)
Proc. Natl. Acad. Sci. USA.
, vol.100
, pp. 8384-8388
-
-
Lieberman, S.M.1
Evans, A.M.2
Han, B.3
Takaki, T.4
Vinnitskaya, Y.5
Caldwell, J.A.6
Serreze, D.V.7
Shabanowitz, J.8
Hunt, D.F.9
Nathenson, S.G.10
-
15
-
-
0036794559
-
Molecular anatomy of antigen-specific CD8(+) T cell engagement and synapse formation in vivo
-
McGavern, D.B., U. Christen, and M.B. Oldstone. 2002. Molecular anatomy of antigen-specific CD8(+) T cell engagement and synapse formation in vivo. Nat. Immunol. 3:918-925. http://dx.doi.org/10.1038/ni843
-
(2002)
Nat. Immunol.
, vol.3
, pp. 918-925
-
-
McGavern, D.B.1
Christen, U.2
Oldstone, M.B.3
-
16
-
-
27744603796
-
Sustained beta cell apoptosis in patients with long-standing type 1 diabetes: indirect evidence for islet regeneration?
-
Meier, J.J., A. Bhushan, A.E. Butler, R.A. Rizza, and P.C. Butler. 2005. Sustained beta cell apoptosis in patients with long-standing type 1 diabetes: indirect evidence for islet regeneration? Diabetologia. 48:2221-2228. http://dx.doi.org/10.1007/s00125-005-1949-2
-
(2005)
Diabetologia
, vol.48
, pp. 2221-2228
-
-
Meier, J.J.1
Bhushan, A.2
Butler, A.E.3
Rizza, R.A.4
Butler, P.C.5
-
17
-
-
0242300571
-
Identification of a beta-cell-specific HLA class I restricted epitope in type 1 diabetes
-
Panagiotopoulos, C., H. Qin, R. Tan, and C.B. Verchere. 2003. Identification of a beta-cell-specific HLA class I restricted epitope in type 1 diabetes. Diabetes. 52:2647-2651. http://dx.doi.org/10.2337/diabetes.52.11.2647
-
(2003)
Diabetes
, vol.52
, pp. 2647-2651
-
-
Panagiotopoulos, C.1
Qin, H.2
Tan, R.3
Verchere, C.B.4
-
18
-
-
0028955372
-
Cytotoxic T cells specific for glutamic acid decarboxylase in autoimmune diabetes
-
Panina-Bordignon, P., R. Lang, P.M. van Endert, E. Benazzi, A.M. Felix, R.M. Pastore, G.A. Spinas, and F. Sinigaglia. 1995. Cytotoxic T cells specific for glutamic acid decarboxylase in autoimmune diabetes. J. Exp. Med. 181:1923-1927. http://dx.doi.org/10.1084/jem.181.5.1923
-
(1995)
J. Exp. Med.
, vol.181
, pp. 1923-1927
-
-
Panina-Bordignon, P.1
Lang, R.2
van Endert, P.M.3
Benazzi, E.4
Felix, A.M.5
Pastore, R.M.6
Spinas, G.A.7
Sinigaglia, F.8
-
19
-
-
28444489322
-
Physiopathology and genetics of vitiligo
-
Passeron, T., and J.P. Ortonne. 2005. Physiopathology and genetics of vitiligo. J. Autoimmun. 25(Suppl):63-68. http://dx.doi.org/10.1016/j.jaut.2005.10.001
-
(2005)
J. Autoimmun.
, vol.25
, Issue.SUPPL.
, pp. 63-68
-
-
Passeron, T.1
Ortonne, J.P.2
-
20
-
-
77956360380
-
Antigen-specific immunotherapy for type 1 diabetes: maximizing the potential
-
Peakman, M., and M. von Herrath. 2010. Antigen-specific immunotherapy for type 1 diabetes: maximizing the potential. Diabetes. 59:2087-2093. http://dx.doi.org/10.2337/db10-0630
-
(2010)
Diabetes
, vol.59
, pp. 2087-2093
-
-
Peakman, M.1
von Herrath, M.2
-
21
-
-
29444433680
-
Autoreactive CD8 T cells associated with beta cell destruction in type 1 diabetes
-
Pinkse, G.G., O.H. Tysma, C.A. Bergen, M.G. Kester, F. Ossendorp, P.A. van Veelen, B. Keymeulen, D. Pipeleers, J.W. Drijfhout, and B.O. Roep. 2005. Autoreactive CD8 T cells associated with beta cell destruction in type 1 diabetes. Proc. Natl. Acad. Sci. USA. 102:18425-18430. http://dx.doi.org/10.1073/pnas.0508621102
-
(2005)
Proc. Natl. Acad. Sci. USA.
, vol.102
, pp. 18425-18430
-
-
Pinkse, G.G.1
Tysma, O.H.2
Bergen, C.A.3
Kester, M.G.4
Ossendorp, F.5
van Veelen, P.A.6
Keymeulen, B.7
Pipeleers, D.8
Drijfhout, J.W.9
Roep, B.O.10
-
22
-
-
56249084560
-
The beta cell population in type 1 diabetes
-
discussion :24-31: 122-129: 202-203
-
Pipeleers, D., P. In't Veld, M. Pipeleers-Marichal, and F. Gorus. 2008. The beta cell population in type 1 diabetes. Novartis Found. Symp. 292:19-24, discussion :24-31: 122-129: 202-203. http://dx.doi.org/10.1002/9780470697405.ch3
-
(2008)
Novartis Found. Symp.
, vol.292
, pp. 19-24
-
-
Pipeleers, D.1
In't Veld, P.2
Pipeleers-Marichal, M.3
Gorus, F.4
-
23
-
-
75649134941
-
Surrogate end points in the design of immunotherapy trials: emerging lessons from type 1 diabetes
-
Roep, B.O., and M. Peakman. 2010. Surrogate end points in the design of immunotherapy trials: emerging lessons from type 1 diabetes. Nat. Rev. Immunol. 10:145-152. http://dx.doi.org/10.1038/nri2705
-
(2010)
Nat. Rev. Immunol.
, vol.10
, pp. 145-152
-
-
Roep, B.O.1
Peakman, M.2
-
24
-
-
55849116389
-
CTLs are targeted to kill beta cells in patients with type 1 diabetes through recognition of a glucose-regulated preproinsulin epitope
-
Skowera, A., R.J. Ellis, R. Varela-Calviño, S. Arif, G.C. Huang, C. Van-Krinks, A. Zaremba, C. Rackham, J.S. Allen, T.I. Tree, et al. 2008. CTLs are targeted to kill beta cells in patients with type 1 diabetes through recognition of a glucose-regulated preproinsulin epitope. J. Clin. Invest. 118:3390-3402.
-
(2008)
J. Clin. Invest.
, vol.118
, pp. 3390-3402
-
-
Skowera, A.1
Ellis, R.J.2
Varela-Calviño, R.3
Arif, S.4
Huang, G.C.5
Van-Krinks, C.6
Zaremba, A.7
Rackham, C.8
Allen, J.S.9
Tree, T.I.10
-
25
-
-
0035013090
-
Cytotoxic T cells to an epitope in the islet autoantigen IA-2 are not disease-specific
-
Takahashi, K., M.C. Honeyman, and L.C. Harrison. 2001. Cytotoxic T cells to an epitope in the islet autoantigen IA-2 are not disease-specific. Clin. Immunol. 99:360-364. http://dx.doi.org/10.1006/clim.2001.5031
-
(2001)
Clin. Immunol.
, vol.99
, pp. 360-364
-
-
Takahashi, K.1
Honeyman, M.C.2
Harrison, L.C.3
-
26
-
-
0031647592
-
A pyramid approach to subpixel registration based on intensity
-
Thévenaz, P., U.E. Ruttimann, and M. Unser. 1998. A pyramid approach to subpixel registration based on intensity. IEEE Trans. Image Process. 7:27-41. http://dx.doi.org/10.1109/83.650848
-
(1998)
IEEE Trans. Image Process.
, vol.7
, pp. 27-41
-
-
Thévenaz, P.1
Ruttimann, U.E.2
Unser, M.3
-
27
-
-
0037237655
-
Prediction of spontaneous autoimmune diabetes in NOD mice by quantification of autoreactive T cells in peripheral blood
-
Trudeau, J.D., C. Kelly-Smith, C.B. Verchere, J.F. Elliott, J.P. Dutz, D.T. Finegood, P. Santamaria, and R. Tan. 2003. Prediction of spontaneous autoimmune diabetes in NOD mice by quantification of autoreactive T cells in peripheral blood. J. Clin. Invest. 111:217-223.
-
(2003)
J. Clin. Invest.
, vol.111
, pp. 217-223
-
-
Trudeau, J.D.1
Kelly-Smith, C.2
Verchere, C.B.3
Elliott, J.F.4
Dutz, J.P.5
Finegood, D.T.6
Santamaria, P.7
Tan, R.8
-
28
-
-
34249107054
-
Human clonal CD8 autoreactivity to an IGRP islet epitope shared between mice and men
-
Unger, W.W., G.G. Pinkse, S. Mulder-van der Kracht, A.R. van der Slik, M.G. Kester, F. Ossendorp, J.W. Drijfhout, D.V. Serreze, and B.O. Roep. 2007. Human clonal CD8 autoreactivity to an IGRP islet epitope shared between mice and men. Ann. N. Y. Acad. Sci. 1103:192-195. http://dx.doi.org/10.1196/annals.1394.024
-
(2007)
Ann. N. Y. Acad. Sci.
, vol.1103
, pp. 192-195
-
-
Unger, W.W.1
Pinkse, G.G.2
Mulder-van der Kracht, S.3
van der Slik, A.R.4
Kester, M.G.5
Ossendorp, F.6
Drijfhout, J.W.7
Serreze, D.V.8
Roep, B.O.9
-
29
-
-
78751662679
-
Type 1 diabetes: etiology, immunology, and therapeutic strategies
-
van Belle, T.L., K.T. Coppieters, and M.G. von Herrath. 2011. Type 1 diabetes: etiology, immunology, and therapeutic strategies. Physiol. Rev. 91:79-118. http://dx.doi.org/10.1152/physrev.00003.2010
-
(2011)
Physiol. Rev.
, vol.91
, pp. 79-118
-
-
van Belle, T.L.1
Coppieters, K.T.2
von Herrath, M.G.3
-
30
-
-
34247154341
-
Autologous nonmyeloablative hematopoietic stem cell transplantation in newly diagnosed type 1 diabetes mellitus
-
Voltarelli, J.C., C.E. Couri, A.B. Stracieri, M.C. Oliveira, D.A. Moraes, F. Pieroni, M. Coutinho, K.C. Malmegrim, M.C. Foss-Freitas, B.P. Simões, et al. 2007. Autologous nonmyeloablative hematopoietic stem cell transplantation in newly diagnosed type 1 diabetes mellitus. JAMA. 297:1568-1576. http://dx.doi.org/10.1001/jama.297.14.1568
-
(2007)
JAMA
, vol.297
, pp. 1568-1576
-
-
Voltarelli, J.C.1
Couri, C.E.2
Stracieri, A.B.3
Oliveira, M.C.4
Moraes, D.A.5
Pieroni, F.6
Coutinho, M.7
Malmegrim, K.C.8
Foss-Freitas, M.C.9
Simões, B.P.10
-
31
-
-
58149299735
-
Analysis of islet inflammation in human type 1 diabetes
-
Willcox, A., S.J. Richardson, A.J. Bone, A.K. Foulis, and N.G. Morgan. 2009. Analysis of islet inflammation in human type 1 diabetes. Clin. Exp. Immunol. 155:173-181. http://dx.doi.org/10.1111/j.1365-2249.2008.03860.x
-
(2009)
Clin. Exp. Immunol.
, vol.155
, pp. 173-181
-
-
Willcox, A.1
Richardson, S.J.2
Bone, A.J.3
Foulis, A.K.4
Morgan, N.G.5
-
32
-
-
33846550244
-
Identical beta cell-specific CD8(+) T cell clonotypes typically reside in both peripheral blood lymphocyte and pancreatic islets
-
Wong, C.P., R. Stevens, B. Long, L. Li, Y. Wang, M.A. Wallet, K.S. Goudy, J.A. Frelinger, and R. Tisch. 2007. Identical beta cell-specific CD8(+) T cell clonotypes typically reside in both peripheral blood lymphocyte and pancreatic islets. J. Immunol. 178:1388-1395.
-
(2007)
J. Immunol.
, vol.178
, pp. 1388-1395
-
-
Wong, C.P.1
Stevens, R.2
Long, B.3
Li, L.4
Wang, Y.5
Wallet, M.A.6
Goudy, K.S.7
Frelinger, J.A.8
Tisch, R.9
-
33
-
-
79951796881
-
Prediction and prevention of Type 1 diabetes mellitus
-
Zhang, L., and G.S. Eisenbarth. 2011. Prediction and prevention of Type 1 diabetes mellitus. J Diabetes. 3:48-57. http://dx.doi.org/10.1111/j.1753-0407.2010.00102.x
-
(2011)
J Diabetes
, vol.3
, pp. 48-57
-
-
Zhang, L.1
Eisenbarth, G.S.2
|