메뉴 건너뛰기




Volumn 7, Issue OCT, 2016, Pages

Minimal residual disease detection and evolved IGH clones analysis in acute b lymphoblastic leukemia using IGH deep sequencing

Author keywords

Acute B lymphoblast leukemia; High throughput sequencing; IGH, clonal evolution; Minimal residual disease

Indexed keywords

IMMUNOGLOBULIN; IMMUNOGLOBULIN HEAVY CHAIN; T LYMPHOCYTE RECEPTOR;

EID: 84997284732     PISSN: None     EISSN: 16643224     Source Type: Journal    
DOI: 10.3389/fimmu.2016.00403     Document Type: Article
Times cited : (32)

References (46)
  • 1
    • 77953022239 scopus 로고    scopus 로고
    • Epidemiology of childhood cancer
    • Kaatsch P. Epidemiology of childhood cancer. Cancer Treat Rev (2010) 36(4):277-85. doi:10.1016/j.ctrv.2010.02.003.
    • (2010) Cancer Treat Rev , vol.36 , Issue.4 , pp. 277-285
    • Kaatsch, P.1
  • 2
    • 84933507862 scopus 로고    scopus 로고
    • Clinical utility of sequential minimal residual disease measurements in the context of risk-based therapy in childhood acute lymphoblastic leukaemia: a prospective study
    • Pui CH, Pei D, Coustan-Smith E, Jeha S, Cheng C, Bowman WP, et al. Clinical utility of sequential minimal residual disease measurements in the context of risk-based therapy in childhood acute lymphoblastic leukaemia: a prospective study. Lancet Oncol (2015) 16(4):465-74. doi:10.1016/S1470-2045(15)70082-3.
    • (2015) Lancet Oncol , vol.16 , Issue.4 , pp. 465-474
    • Pui, C.H.1    Pei, D.2    Coustan-Smith, E.3    Jeha, S.4    Cheng, C.5    Bowman, W.P.6
  • 3
    • 80052172961 scopus 로고    scopus 로고
    • Late MRD response determines relapse risk overall and in subsets of childhood T-cell ALL: results of the AIEOP-BFM-ALL 2000 study
    • Schrappe M, Valsecchi MG, Bartram CR, Schrauder A, Panzer-Grumayer R, Moricke A, et al. Late MRD response determines relapse risk overall and in subsets of childhood T-cell ALL: results of the AIEOP-BFM-ALL 2000 study. Blood (2011) 118(8):2077-84. doi:10.1182/blood-2011-03-338707.
    • (2011) Blood , vol.118 , Issue.8 , pp. 2077-2084
    • Schrappe, M.1    Valsecchi, M.G.2    Bartram, C.R.3    Schrauder, A.4    Panzer-Grumayer, R.5    Moricke, A.6
  • 4
    • 0032576355 scopus 로고    scopus 로고
    • Prognostic value of minimal residual disease in acute lymphoblastic leukaemia in childhood
    • van Dongen JJ, Seriu T, Panzer-Grumayer ER, Biondi A, Pongers-Willemse MJ, Corral L, et al. Prognostic value of minimal residual disease in acute lymphoblastic leukaemia in childhood. Lancet (1998) 352(9142):1731-8. doi:10.1016/S0140-6736(98)04058-6.
    • (1998) Lancet , vol.352 , Issue.9142 , pp. 1731-1738
    • van Dongen, J.J.1    Seriu, T.2    Panzer-Grumayer, E.R.3    Biondi, A.4    Pongers-Willemse, M.J.5    Corral, L.6
  • 5
    • 47049093795 scopus 로고    scopus 로고
    • Clinical significance of minimal residual disease in childhood acute lymphoblastic leukemia and its relationship to other prognostic factors: a Children's Oncology Group study
    • Borowitz MJ, Devidas M, Hunger SP, Bowman WP, Carroll AJ, Carroll WL, et al. Clinical significance of minimal residual disease in childhood acute lymphoblastic leukemia and its relationship to other prognostic factors: a Children's Oncology Group study. Blood (2008) 111(12):5477-85. doi:10.1182/blood-2008-01-132837.
    • (2008) Blood , vol.111 , Issue.12 , pp. 5477-5485
    • Borowitz, M.J.1    Devidas, M.2    Hunger, S.P.3    Bowman, W.P.4    Carroll, A.J.5    Carroll, W.L.6
  • 6
    • 79955005365 scopus 로고    scopus 로고
    • Minimal residual disease in acute lymphoblastic leukemia
    • Campana D. Minimal residual disease in acute lymphoblastic leukemia. Hematology Am Soc Hematol Educ Program (2010) 2010:7-12. doi:10.1182/asheducation-2010.1.7.
    • (2010) Hematology Am Soc Hematol Educ Program , vol.2010 , pp. 7-12
    • Campana, D.1
  • 7
    • 0036009608 scopus 로고    scopus 로고
    • Molecular monitoring of residual disease using antigen receptor genes in childhood acute lymphoblastic leukaemia
    • Szczepanski T, Flohr T, van der Velden VH, Bartram CR, van Dongen JJ. Molecular monitoring of residual disease using antigen receptor genes in childhood acute lymphoblastic leukaemia. Best Pract Res Clin Haematol (2002) 15(1):37-57. doi:10.1053/beha.2002.0184.
    • (2002) Best Pract Res Clin Haematol , vol.15 , Issue.1 , pp. 37-57
    • Szczepanski, T.1    Flohr, T.2    van der Velden, V.H.3    Bartram, C.R.4    van Dongen, J.J.5
  • 8
    • 77954727839 scopus 로고    scopus 로고
    • Clinical significance of low levels of minimal residual disease at the end of remission induction therapy in childhood acute lymphoblastic leukemia
    • Stow P, Key L, Chen X, Pan Q, Neale GA, Coustan-Smith E, et al. Clinical significance of low levels of minimal residual disease at the end of remission induction therapy in childhood acute lymphoblastic leukemia. Blood (2010) 115(23):4657-63. doi:10.1182/blood-2009-11-253435.
    • (2010) Blood , vol.115 , Issue.23 , pp. 4657-4663
    • Stow, P.1    Key, L.2    Chen, X.3    Pan, Q.4    Neale, G.A.5    Coustan-Smith, E.6
  • 9
    • 84983390197 scopus 로고    scopus 로고
    • Implications of minimal residual disease by flow cytometry in pediatric acute leukemias
    • din-Cinar SA, Can Kucuksezer U, Deniz G. Implications of minimal residual disease by flow cytometry in pediatric acute leukemias. Int Trends Immunity (2013) 1(4):54-61.
    • (2013) Int Trends Immunity , vol.1 , Issue.4 , pp. 54-61
    • din-Cinar, S.A.1    Can Kucuksezer, U.2    Deniz, G.3
  • 10
    • 77952604861 scopus 로고    scopus 로고
    • Immaturity associated antigens are lost during induction for T cell lymphoblastic leukemia: implications for minimal residual disease detection
    • Roshal M, Fromm JR, Winter S, Dunsmore K, Wood BL. Immaturity associated antigens are lost during induction for T cell lymphoblastic leukemia: implications for minimal residual disease detection. Cytometry B Clin Cytom (2010) 78(3):139-46. doi:10.1002/cyto.b.20511.
    • (2010) Cytometry B Clin Cytom , vol.78 , Issue.3 , pp. 139-146
    • Roshal, M.1    Fromm, J.R.2    Winter, S.3    Dunsmore, K.4    Wood, B.L.5
  • 11
    • 19944428207 scopus 로고    scopus 로고
    • Drug-induced immunophenotypic modulation in childhood ALL: implications for minimal residual disease detection
    • Gaipa G, Basso G, Maglia O, Leoni V, Faini A, Cazzaniga G, et al. Drug-induced immunophenotypic modulation in childhood ALL: implications for minimal residual disease detection. Leukemia (2005) 19(1):49-56. doi:10.1038/sj.leu.2403559.
    • (2005) Leukemia , vol.19 , Issue.1 , pp. 49-56
    • Gaipa, G.1    Basso, G.2    Maglia, O.3    Leoni, V.4    Faini, A.5    Cazzaniga, G.6
  • 12
    • 0004783768 scopus 로고    scopus 로고
    • Cytogenetic findings in a population-based series of 787 childhood acute lymphoblastic leukemias from the Nordic countries. The NOPHO Leukemia Cytogenetic Study Group
    • Forestier E, Johansson B, Borgstrom G, Kerndrup G, Johansson J, Heim S. Cytogenetic findings in a population-based series of 787 childhood acute lymphoblastic leukemias from the Nordic countries. The NOPHO Leukemia Cytogenetic Study Group. Eur J Haematol (2000) 64(3):194-200. doi:10.1034/j.1600-0609.2000.90103.x.
    • (2000) Eur J Haematol , vol.64 , Issue.3 , pp. 194-200
    • Forestier, E.1    Johansson, B.2    Borgstrom, G.3    Kerndrup, G.4    Johansson, J.5    Heim, S.6
  • 13
    • 0038040665 scopus 로고    scopus 로고
    • Detection of minimal residual disease in hematologic malignancies by real-time quantitative PCR: principles, approaches, and laboratory aspects
    • van der Velden VH, Hochhaus A, Cazzaniga G, Szczepanski T, Gabert J, van Dongen JJ. Detection of minimal residual disease in hematologic malignancies by real-time quantitative PCR: principles, approaches, and laboratory aspects. Leukemia (2003) 17(6):1013-34. doi:10.1038/sj.leu.2402922.
    • (2003) Leukemia , vol.17 , Issue.6 , pp. 1013-1034
    • van der Velden, V.H.1    Hochhaus, A.2    Cazzaniga, G.3    Szczepanski, T.4    Gabert, J.5    van Dongen, J.J.6
  • 14
    • 33947381440 scopus 로고    scopus 로고
    • Optimization of PCR-based minimal residual disease diagnostics for childhood acute lymphoblastic leukemia in a multi-center setting
    • van der Velden VH, Panzer-Grumayer ER, Cazzaniga G, Flohr T, Sutton R, Schrauder A, et al. Optimization of PCR-based minimal residual disease diagnostics for childhood acute lymphoblastic leukemia in a multi-center setting. Leukemia (2007) 21(4):706-13. doi:10.1038/sj.leu.2404535.
    • (2007) Leukemia , vol.21 , Issue.4 , pp. 706-713
    • van der Velden, V.H.1    Panzer-Grumayer, E.R.2    Cazzaniga, G.3    Flohr, T.4    Sutton, R.5    Schrauder, A.6
  • 15
    • 15244340145 scopus 로고    scopus 로고
    • Molecular monitoring of childhood acute lymphoblastic leukemia using antigen receptor gene rearrangements and quantitative polymerase chain reaction technology
    • Cazzaniga G, Biondi A. Molecular monitoring of childhood acute lymphoblastic leukemia using antigen receptor gene rearrangements and quantitative polymerase chain reaction technology. Haematologica (2005) 90(3):382-90.
    • (2005) Haematologica , vol.90 , Issue.3 , pp. 382-390
    • Cazzaniga, G.1    Biondi, A.2
  • 16
    • 84861120541 scopus 로고    scopus 로고
    • High-throughput sequencing detects minimal residual disease in acute T lymphoblastic leukemia
    • Wu D, Sherwood A, Fromm JR, Winter SS, Dunsmore KP, Loh ML, et al. High-throughput sequencing detects minimal residual disease in acute T lymphoblastic leukemia. Sci Transl Med (2012) 4(134):134ra63. doi:10.1126/scitranslmed.3003656.
    • (2012) Sci Transl Med , vol.4 , Issue.134
    • Wu, D.1    Sherwood, A.2    Fromm, J.R.3    Winter, S.S.4    Dunsmore, K.P.5    Loh, M.L.6
  • 17
    • 84905490286 scopus 로고    scopus 로고
    • Detection of minimal residual disease in B lymphoblastic leukemia by high-throughput sequencing of IGH
    • Wu D, Emerson RO, Sherwood A, Loh ML, Angiolillo A, Howie B, et al. Detection of minimal residual disease in B lymphoblastic leukemia by high-throughput sequencing of IGH. Clin Cancer Res (2014) 20(17):4540-8. doi:10.1158/1078-0432.CCR-13-3231.
    • (2014) Clin Cancer Res , vol.20 , Issue.17 , pp. 4540-4548
    • Wu, D.1    Emerson, R.O.2    Sherwood, A.3    Loh, M.L.4    Angiolillo, A.5    Howie, B.6
  • 18
    • 84871525322 scopus 로고    scopus 로고
    • Deep-sequencing approach for minimal residual disease detection in acute lymphoblastic leukemia
    • Faham M, Zheng J, Moorhead M, Carlton VE, Stow P, Coustan-Smith E, et al. Deep-sequencing approach for minimal residual disease detection in acute lymphoblastic leukemia. Blood (2012) 120(26):5173-80. doi:10.1182/blood-2012-07-444042.
    • (2012) Blood , vol.120 , Issue.26 , pp. 5173-5180
    • Faham, M.1    Zheng, J.2    Moorhead, M.3    Carlton, V.E.4    Stow, P.5    Coustan-Smith, E.6
  • 19
    • 34447295435 scopus 로고    scopus 로고
    • Monitoring of minimal residual disease in adult acute myeloid leukemia using peripheral blood as an alternative source to bone marrow
    • Maurillo L, Buccisano F, Spagnoli A, Del Poeta G, Panetta P, Neri B, et al. Monitoring of minimal residual disease in adult acute myeloid leukemia using peripheral blood as an alternative source to bone marrow. Haematologica (2007) 92(5):605-11. doi:10.3324/haematol.10432.
    • (2007) Haematologica , vol.92 , Issue.5 , pp. 605-611
    • Maurillo, L.1    Buccisano, F.2    Spagnoli, A.3    Del Poeta, G.4    Panetta, P.5    Neri, B.6
  • 20
    • 0036786910 scopus 로고    scopus 로고
    • Use of peripheral blood instead of bone marrow to monitor residual disease in children with acute lymphoblastic leukemia
    • Coustan-Smith E, Sancho J, Hancock ML, Razzouk BI, Ribeiro RC, Rivera GK, et al. Use of peripheral blood instead of bone marrow to monitor residual disease in children with acute lymphoblastic leukemia. Blood (2002) 100(7):2399-402. doi:10.1182/blood-2002-04-1130.
    • (2002) Blood , vol.100 , Issue.7 , pp. 2399-2402
    • Coustan-Smith, E.1    Sancho, J.2    Hancock, M.L.3    Razzouk, B.I.4    Ribeiro, R.C.5    Rivera, G.K.6
  • 21
    • 0023202527 scopus 로고
    • Generation of drug-resistant variants in metastatic B16 mouse melanoma cell lines
    • Cillo C, Dick JE, Ling V, Hill RP. Generation of drug-resistant variants in metastatic B16 mouse melanoma cell lines. Cancer Res (1987) 47(10):2604-8.
    • (1987) Cancer Res , vol.47 , Issue.10 , pp. 2604-2608
    • Cillo, C.1    Dick, J.E.2    Ling, V.3    Hill, R.P.4
  • 22
    • 84872176951 scopus 로고    scopus 로고
    • Clonal evolution of acute leukemia genomes
    • Jan M, Majeti R. Clonal evolution of acute leukemia genomes. Oncogene (2013) 32(2):135-40. doi:10.1038/onc.2012.48.
    • (2013) Oncogene , vol.32 , Issue.2 , pp. 135-140
    • Jan, M.1    Majeti, R.2
  • 23
    • 84931562132 scopus 로고    scopus 로고
    • Mechanisms of clonal evolution in childhood acute lymphoblastic leukemia
    • Swaminathan S, Klemm L, Park E, Papaemmanuil E, Ford A, Kweon SM, et al. Mechanisms of clonal evolution in childhood acute lymphoblastic leukemia. Nat Immunol (2015) 16(7):766-74. doi:10.1038/ni.3160.
    • (2015) Nat Immunol , vol.16 , Issue.7 , pp. 766-774
    • Swaminathan, S.1    Klemm, L.2    Park, E.3    Papaemmanuil, E.4    Ford, A.5    Kweon, S.M.6
  • 24
    • 84869826772 scopus 로고    scopus 로고
    • Massive evolution of the immunoglobulin heavy chain locus in children with B precursor acute lymphoblastic leukemia
    • Gawad C, Pepin F, Carlton VE, Klinger M, Logan AC, Miklos DB, et al. Massive evolution of the immunoglobulin heavy chain locus in children with B precursor acute lymphoblastic leukemia. Blood (2012) 120(22):4407-17. doi:10.1182/blood-2012-05-429811.
    • (2012) Blood , vol.120 , Issue.22 , pp. 4407-4417
    • Gawad, C.1    Pepin, F.2    Carlton, V.E.3    Klinger, M.4    Logan, A.C.5    Miklos, D.B.6
  • 25
    • 84943623597 scopus 로고    scopus 로고
    • IMonitor: a robust pipeline for TCR and BCR repertoire analysis
    • Zhang W, Du Y, Su Z, Wang C, Zeng X, Zhang R, et al. IMonitor: a robust pipeline for TCR and BCR repertoire analysis. Genetics (2015) 201(2):459-72. doi:10.1534/genetics.115.176735.
    • (2015) Genetics , vol.201 , Issue.2 , pp. 459-472
    • Zhang, W.1    Du, Y.2    Su, Z.3    Wang, C.4    Zeng, X.5    Zhang, R.6
  • 26
    • 2342456308 scopus 로고    scopus 로고
    • Nonsense-mediated mRNA decay: terminating erroneous gene expression
    • Baker KE, Parker R. Nonsense-mediated mRNA decay: terminating erroneous gene expression. Curr Opin Cell Biol (2004) 16(3):293-9. doi:10.1016/j.ceb.2004.03.003.
    • (2004) Curr Opin Cell Biol , vol.16 , Issue.3 , pp. 293-299
    • Baker, K.E.1    Parker, R.2
  • 27
    • 33749057696 scopus 로고    scopus 로고
    • Nonsense-mediated mRNA decay modulates clinical outcome of genetic disease
    • Khajavi M, Inoue K, Lupski JR. Nonsense-mediated mRNA decay modulates clinical outcome of genetic disease. Eur J Hum Genet (2006) 14(10):1074-81. doi:10.1038/sj.ejhg.5201649.
    • (2006) Eur J Hum Genet , vol.14 , Issue.10 , pp. 1074-1081
    • Khajavi, M.1    Inoue, K.2    Lupski, J.R.3
  • 28
    • 0036143404 scopus 로고    scopus 로고
    • Changes in gene expression profiles in developing B cells of murine bone marrow
    • Hoffmann R, Seidl T, Neeb M, Rolink A, Melchers F. Changes in gene expression profiles in developing B cells of murine bone marrow. Genome Res (2002) 12(1):98-111. doi:10.1101/gr.201501.
    • (2002) Genome Res , vol.12 , Issue.1 , pp. 98-111
    • Hoffmann, R.1    Seidl, T.2    Neeb, M.3    Rolink, A.4    Melchers, F.5
  • 29
    • 84975137934 scopus 로고    scopus 로고
    • Eye on the B-ALL: B-cell receptor repertoires reveal persistence of numerous B-lymphoblastic leukemia subclones from diagnosis to relapse
    • Bashford-Rogers RJ, Nicolaou KA, Bartram J, Goulden NJ, Loizou L, Koumas L, et al. Eye on the B-ALL: B-cell receptor repertoires reveal persistence of numerous B-lymphoblastic leukemia subclones from diagnosis to relapse. Leukemia (2016). doi:10.1038/leu.2016.142.
    • (2016) Leukemia
    • Bashford-Rogers, R.J.1    Nicolaou, K.A.2    Bartram, J.3    Goulden, N.J.4    Loizou, L.5    Koumas, L.6
  • 30
    • 0020534965 scopus 로고
    • Somatic generation of antibody diversity
    • Tonegawa S. Somatic generation of antibody diversity. Nature (1983) 302(5909):575-81. doi:10.1038/302575a0.
    • (1983) Nature , vol.302 , Issue.5909 , pp. 575-581
    • Tonegawa, S.1
  • 31
    • 13444252473 scopus 로고    scopus 로고
    • V(H) replacement in rearranged immunoglobulin genes
    • Darlow JM, Stott DI. V(H) replacement in rearranged immunoglobulin genes. Immunology (2005) 114(2):155-65. doi:10.1111/j.1365-2567.2004.02084.x.
    • (2005) Immunology , vol.114 , Issue.2 , pp. 155-165
    • Darlow, J.M.1    Stott, D.I.2
  • 32
    • 0025365924 scopus 로고
    • Minimal residual disease in childhood B-lineage lymphoblastic leukemia. Persistence of leukemic cells during the first 18 months of treatment
    • Yamada M, Wasserman R, Lange B, Reichard BA, Womer RB, Rovera G. Minimal residual disease in childhood B-lineage lymphoblastic leukemia. Persistence of leukemic cells during the first 18 months of treatment. N Engl J Med (1990) 323(7):448-55. doi:10.1056/NEJM199008163230705.
    • (1990) N Engl J Med , vol.323 , Issue.7 , pp. 448-455
    • Yamada, M.1    Wasserman, R.2    Lange, B.3    Reichard, B.A.4    Womer, R.B.5    Rovera, G.6
  • 33
    • 42349085052 scopus 로고    scopus 로고
    • Minimal residual disease-directed risk stratification using real-time quantitative PCR analysis of immunoglobulin and T-cell receptor gene rearrangements in the international multicenter trial AIEOP-BFM ALL 2000 for childhood acute lymphoblastic leukemia
    • Flohr T, Schrauder A, Cazzaniga G, Panzer-Grumayer R, van der Velden V, Fischer S, et al. Minimal residual disease-directed risk stratification using real-time quantitative PCR analysis of immunoglobulin and T-cell receptor gene rearrangements in the international multicenter trial AIEOP-BFM ALL 2000 for childhood acute lymphoblastic leukemia. Leukemia (2008) 22(4):771-82. doi:10.1038/leu.2008.5.
    • (2008) Leukemia , vol.22 , Issue.4 , pp. 771-782
    • Flohr, T.1    Schrauder, A.2    Cazzaniga, G.3    Panzer-Grumayer, R.4    van der Velden, V.5    Fischer, S.6
  • 34
    • 65649122270 scopus 로고    scopus 로고
    • High-throughput sequencing of the zebrafish antibody repertoire
    • Weinstein JA, Jiang N, White RA III, Fisher DS, Quake SR. High-throughput sequencing of the zebrafish antibody repertoire. Science (2009) 324(5928):807-10. doi:10.1126/science.1170020.
    • (2009) Science , vol.324 , Issue.5928 , pp. 807-810
    • Weinstein, J.A.1    Jiang, N.2    White, R.A.3    Fisher, D.S.4    Quake, S.R.5
  • 35
    • 77950541195 scopus 로고    scopus 로고
    • Comprehensive assessment of T-cell receptor beta-chain diversity in alphabeta T cells
    • Robins HS, Campregher PV, Srivastava SK, Wacher A, Turtle CJ, Kahsai O, et al. Comprehensive assessment of T-cell receptor beta-chain diversity in alphabeta T cells. Blood (2009) 114(19):4099-107. doi:10.1182/blood-2009-04-217604.
    • (2009) Blood , vol.114 , Issue.19 , pp. 4099-4107
    • Robins, H.S.1    Campregher, P.V.2    Srivastava, S.K.3    Wacher, A.4    Turtle, C.J.5    Kahsai, O.6
  • 36
    • 77954601328 scopus 로고    scopus 로고
    • Measurement and clinical monitoring of human lymphocyte clonality by massively parallel VDJ pyrosequencing
    • Boyd SD, Marshall EL, Merker JD, Maniar JM, Zhang LN, Sahaf B, et al. Measurement and clinical monitoring of human lymphocyte clonality by massively parallel VDJ pyrosequencing. Sci Transl Med (2009) 1(12):12ra23. doi:10.1126/scitranslmed.3000540.
    • (2009) Sci Transl Med , vol.1 , Issue.12
    • Boyd, S.D.1    Marshall, E.L.2    Merker, J.D.3    Maniar, J.M.4    Zhang, L.N.5    Sahaf, B.6
  • 37
    • 67149110379 scopus 로고    scopus 로고
    • Determining the repertoire of IGH gene rearrangements to develop molecular markers for minimal residual disease in B-lineage acute lymphoblastic leukemia
    • Brisco MJ, Latham S, Sutton R, Hughes E, Wilczek V, van Zanten K, et al. Determining the repertoire of IGH gene rearrangements to develop molecular markers for minimal residual disease in B-lineage acute lymphoblastic leukemia. J Mol Diagn (2009) 11(3):194-200. doi:10.2353/jmoldx.2009.080047.
    • (2009) J Mol Diagn , vol.11 , Issue.3 , pp. 194-200
    • Brisco, M.J.1    Latham, S.2    Sutton, R.3    Hughes, E.4    Wilczek, V.5    van Zanten, K.6
  • 38
    • 0030780189 scopus 로고    scopus 로고
    • Early onset of immunoglobulin heavy chain gene rearrangements in normal human bone marrow CD34 + cells
    • Davi F, Faili A, Gritti C, Blanc C, Laurent C, Sutton L, et al. Early onset of immunoglobulin heavy chain gene rearrangements in normal human bone marrow CD34 + cells. Blood (1997) 90(10):4014-21.
    • (1997) Blood , vol.90 , Issue.10 , pp. 4014-4021
    • Davi, F.1    Faili, A.2    Gritti, C.3    Blanc, C.4    Laurent, C.5    Sutton, L.6
  • 39
    • 0034234756 scopus 로고    scopus 로고
    • Fates of human B-cell precursors
    • LeBien TW. Fates of human B-cell precursors. Blood (2000) 96(1):9-23.
    • (2000) Blood , vol.96 , Issue.1 , pp. 9-23
    • LeBien, T.W.1
  • 40
    • 11144247047 scopus 로고    scopus 로고
    • The pre-BCR checkpoint as a cell-autonomous proliferation switch
    • Hendriks RW, Middendorp S. The pre-BCR checkpoint as a cell-autonomous proliferation switch. Trends Immunol (2004) 25(5):249-56. doi:10.1016/j.it.2004.02.011.
    • (2004) Trends Immunol , vol.25 , Issue.5 , pp. 249-256
    • Hendriks, R.W.1    Middendorp, S.2
  • 42
    • 1542313885 scopus 로고    scopus 로고
    • The BCR-ABL1 kinase bypasses selection for the expression of a pre-B cell receptor in pre-B acute lymphoblastic leukemia cells
    • Klein F, Feldhahn N, Harder L, Wang H, Wartenberg M, Hofmann WK, et al. The BCR-ABL1 kinase bypasses selection for the expression of a pre-B cell receptor in pre-B acute lymphoblastic leukemia cells. J Exp Med (2004) 199(5):673-85. doi:10.1084/jem.20031637.
    • (2004) J Exp Med , vol.199 , Issue.5 , pp. 673-685
    • Klein, F.1    Feldhahn, N.2    Harder, L.3    Wang, H.4    Wartenberg, M.5    Hofmann, W.K.6
  • 43
    • 84938988115 scopus 로고    scopus 로고
    • The pre B cell receptor checkpoint in acute lymphoblastic leukaemia
    • Eswaran J, Sinclair P, Heidenreich O, Irving J, Russell LJ, Hall A, et al. The pre B cell receptor checkpoint in acute lymphoblastic leukaemia. Leukemia (2015) 29(8):1623-31. doi:10.1038/leu.2015.113.
    • (2015) Leukemia , vol.29 , Issue.8 , pp. 1623-1631
    • Eswaran, J.1    Sinclair, P.2    Heidenreich, O.3    Irving, J.4    Russell, L.J.5    Hall, A.6
  • 44
    • 84880880724 scopus 로고    scopus 로고
    • New insights into pre-BCR and BCR signalling with relevance to B cell malignancies
    • Rickert RC. New insights into pre-BCR and BCR signalling with relevance to B cell malignancies. Nat Rev Immunol (2013) 13(8):578-91. doi:10.1038/nri3487.
    • (2013) Nat Rev Immunol , vol.13 , Issue.8 , pp. 578-591
    • Rickert, R.C.1
  • 45
    • 84930359549 scopus 로고    scopus 로고
    • Mechanisms of pre-B-cell receptor checkpoint control and its oncogenic subversion in acute lymphoblastic leukemia
    • Buchner M, Swaminathan S, Chen Z, Muschen M. Mechanisms of pre-B-cell receptor checkpoint control and its oncogenic subversion in acute lymphoblastic leukemia. Immunol Rev (2015) 263(1):192-209. doi:10.1111/imr.12235.
    • (2015) Immunol Rev , vol.263 , Issue.1 , pp. 192-209
    • Buchner, M.1    Swaminathan, S.2    Chen, Z.3    Muschen, M.4
  • 46
    • 84919372228 scopus 로고    scopus 로고
    • Dissecting the clonal origins of childhood acute lymphoblastic leukemia by single-cell genomics
    • Gawad C, Koh W, Quake SR. Dissecting the clonal origins of childhood acute lymphoblastic leukemia by single-cell genomics. Proc Natl Acad Sci U S A (2014) 111(50):17947-52. doi:10.1073/pnas.1420822111.
    • (2014) Proc Natl Acad Sci U S A , vol.111 , Issue.50 , pp. 17947-17952
    • Gawad, C.1    Koh, W.2    Quake, S.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.