Chronic graft-versus-host-disease in CD34+-humanized NSG mice is associated with human susceptibility HLA haplotypes for autoimmune disease

Journal of Autoimmunity

Volumn 62, Issue , 2015, Pages 55-66

  Sonntag, Katja ^a   Eckert, Franziska ^a   Welker, Christian ^a   Müller, Hartmut ^b   Müller, Friederike ^a   Zips, Daniel ^a   Sipos, Bence ^b   Klein, Reinhild ^a   Blank, Gregor ^a   Feuchtinger, Tobias ^c   Schumm, Michael ^a   Handgretinger, Rupert ^a   Schilbach, Karin ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

^c LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

Author keywords

Autoimmunity; CGVHD model; CGVHD pathology; Chronic graft versus host disease; Extended HLA haplotypes; Humanized mouse; T cell receptor repertoire

Indexed keywords

CD3 ANTIGEN; CD34 ANTIGEN; CD40 LIGAND; GAMMA INTERFERON; HLA ANTIGEN CLASS 1; INTERLEUKIN 10; INTERLEUKIN 13; INTERLEUKIN 17; INTERLEUKIN 4; MACROPHAGE DERIVED CHEMOKINE; MESSENGER RNA; T LYMPHOCYTE RECEPTOR; TRANSCRIPTION FACTOR FOXP3; TRANSCRIPTION FACTOR GATA 3; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; CYTOKINE; HLA ANTIGEN;

ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; AUTOIMMUNITY; B LYMPHOCYTE; CHRONIC GRAFT VERSUS HOST DISEASE; COMPARATIVE STUDY; CONTROLLED STUDY; GENE EXPRESSION; GENETIC POLYMORPHISM; GENETIC SUSCEPTIBILITY; HAPLOTYPE; HEPATITIS; HLA SYSTEM; HUMAN; HUMAN CELL; IMMUNOPATHOGENESIS; LARGE INTESTINE; LIVER; LUNG; MOUSE; NOD SCID GAMMA MOUSE; NONHUMAN; PRIORITY JOURNAL; PSORIASIS; REGULATORY T LYMPHOCYTE; SMALL INTESTINE; T CELL DEPLETION; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; THYMUS; TOOTH MALFORMATION; ALLELE; ANIMAL; AUTOIMMUNE DISEASE; CHRONIC DISEASE; DISEASE MODEL; DISEASE PREDISPOSITION; GENETICS; GRAFT VERSUS HOST REACTION; IMMUNOLOGY; IMMUNOPHENOTYPING; LYMPHOCYTE SUBPOPULATION; METABOLISM; PATHOLOGY; PHENOTYPE;

ALLELES; ANIMALS; AUTOIMMUNE DISEASES; AUTOIMMUNITY; CHRONIC DISEASE; CYTOKINES; DISEASE MODELS, ANIMAL; DISEASE SUSCEPTIBILITY; GENE EXPRESSION; GRAFT VS HOST DISEASE; HAPLOTYPES; HLA ANTIGENS; HUMANS; IMMUNOPHENOTYPING; LYMPHOCYTE SUBSETS; MICE; PHENOTYPE;

EID: 84939561812     PISSN: 08968411     EISSN: 10959157     Source Type: Journal    
DOI: 10.1016/j.jaut.2015.06.006     Document Type: Article

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