Proinsulin-specific, HLA-DQ8, and HLA-DQ8-transdimer-restricted CD4+ T cells infiltrate islets in type 1 diabetes

Diabetes

Volumn 64, Issue 1, 2015, Pages 172-182

  Pathiraja, Vimukthi ^a   Kuehlich, Janine P ^a   Campbell, Peter D ^a   Krishnamurthy, Balasubramanian ^a,b   Loudovaris, Thomas ^a   Coates, P Toby H ^c   Brodnicki, Thomas C ^a,b   O'Connell, Philip J ^d   Kedzierska, Katherine ^b   Rodda, Christine ^b   Bergman, Philip ^e   Hill, Erin ^e   Purcell, Anthony W ^e   Dudek, Nadine L ^e   Thomas, Helen E ^a,b   Kay, Thomas W H ^a,b   Mannering, Stuart I ^a,b  

^a ST VINCENT'S INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c UNIVERSITY OF ADELAIDE   (Australia)

^d UNIVERSITY OF SYDNEY   (Australia)

^e MONASH UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

C PEPTIDE; DIMER; HLA DQ2 ANTIGEN; HLA DQ8 ANTIGEN; PROINSULIN; T LYMPHOCYTE RECEPTOR; HLA DP ANTIGEN; HLA DQ ANTIGEN; HLA DR ANTIGEN;

ANTIGEN PRESENTING CELL; ARTICLE; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN TISSUE; INSULIN DEPENDENT DIABETES MELLITUS; LYMPHOCYTIC INFILTRATION; ORGAN DONOR; PANCREAS ISLET; PATHOGENESIS; PERIPHERAL BLOOD MONONUCLEAR CELL; AUTOIMMUNITY; CELL CULTURE; CHEMISTRY; CYTOLOGY; DIMERIZATION; EPITOPE MAPPING; GENETICS; HETEROZYGOTE; IMMUNOLOGY; PANCREAS ISLET BETA CELL;

AUTOIMMUNITY; CD4-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; DIABETES MELLITUS, TYPE 1; DIMERIZATION; EPITOPE MAPPING; HETEROZYGOTE; HLA-DP ANTIGENS; HLA-DQ ANTIGENS; HLA-DR ANTIGENS; HUMANS; INSULIN-SECRETING CELLS; ISLETS OF LANGERHANS; PROINSULIN;

EID: 84920024469     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db14-0858     Document Type: Article

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