Multiplex identification of antigen-specific T cell receptors using a combination of immune assays and immune receptor sequencing

PLoS ONE

Volumn 10, Issue 10, 2015, Pages

  Klinger, Mark ^a   Pepin, Francois ^a   Wilkins, Jen ^a   Asbury, Thomas ^a   Wittkop, Tobias ^a   Zheng, Jianbiao ^a   Moorhead, Martin ^a   Faham, Malek ^a  

^a Adaptive Biotechnologies South San Francisco   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

T LYMPHOCYTE RECEPTOR; EPITOPE; IMMUNOGLOBULIN RECEPTOR; LYMPHOCYTE ANTIGEN RECEPTOR;

ANTIGEN SPECIFICITY; ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSPOT ASSAY; IMMUNE RECEPTOR SEQUENCING; IMMUNOASSAY; INTERMETHOD COMPARISON; MEASUREMENT REPEATABILITY; MULTIPLEXED IDENTIFICATION OF T CELL RECEPTOR ANTIGEN SPECIFICITY; PREDICTION; QUANTITATIVE ANALYSIS; SENSITIVITY ANALYSIS; SEQUENCE ANALYSIS; VALIDATION PROCESS; CLONAL EVOLUTION; GENETICS; HIGH THROUGHPUT SEQUENCING; HUMAN; IMMUNOLOGY; PROCEDURES; REPRODUCIBILITY; STANDARDS;

CLONAL EVOLUTION; ENZYME-LINKED IMMUNOSPOT ASSAY; EPITOPES, T-LYMPHOCYTE; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; RECEPTORS, ANTIGEN, T-CELL; RECEPTORS, IMMUNOLOGIC; REPRODUCIBILITY OF RESULTS; T-CELL ANTIGEN RECEPTOR SPECIFICITY;

EID: 84949895433     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0141561     Document Type: Article

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