Shared structural motifs in TCR of glycopeptide-recognizing T cell hybridomas

European Journal of Immunology

Volumn 29, Issue 9, 1999, Pages 2759-2768

  Jensen, Teis ^a,c   Hansen, Peter ^a   Nielsen, Anne Faurskov ^b   Meldal, Morten ^b   Komba, Shiro ^a   Werdelin, Ole ^b  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b CARLSBERG LABORATORY   (Denmark)

^c UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Rodent; T lymphocyte; TCR

Indexed keywords

ALANINE; EPITOPE; GLUTAMINE; GLYCINE; GLYCOPEPTIDE; SERINE; T LYMPHOCYTE RECEPTOR; TYROSINE;

AMINO ACID COMPOSITION; ANIMAL CELL; ANTIGEN SPECIFICITY; ARTICLE; CONTROLLED STUDY; DNA SEQUENCE; GENE SEQUENCE; HYBRIDOMA; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN GLYCOSYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; T LYMPHOCYTE;

EID: 0033376778     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1521-4141(199909)29:09<2759::AID-IMMU2759>3.0.CO;2-4     Document Type: Article

References (52)

1. Galli-Stampino, L., Meinjohanns, E., Frische, K., Meldal, M., Jensen, T., Werdelin, O. and Mouritsen, S., T-cell recognition of tumor-associated carbohydrates: the nature of the glycan moiety plays a decisive role in determining glycopeptide immunogenicity. Cancer Res. 1997. 57:3214-3222.
2. Jensen, T., Galli-Stampino, L., Mouritsen, S., Frische, K., Peters, S., Meldal, M. and Werdelin, O., T cell recognition of Tn-glycosylated peptide antigens. Eur. J. Immunol. 1996.26:1342-1349.
3. Ishioka, G. Y., Lamont, A. G., Thomson, D., Bulbow, N., Gaeta, F. C., Sette, A. and Grey, H. M., MHC interactiorx and T cell recognition of carbohydrates and glycopeptides. J. Immunol. 1992.148: 2446-2451.
4. Harding, C. V., Kihlberg, J., Elofsson, M., Magnusson, G. and Unanue, E. R., Glycopeptides bind MHC molecules and elicit specific T cell responses. J. Immunol. 1993.151:2419-2425.
5. Deck, B., Elofsson, M., Kihlberg, J. and Unanue, E. R., Specificity of giycopeptide-specific T cells. J. Immunol. 1995.155:1074-1078.
6. Michaelsson, E., Malmstrom, V., Reis, S., Engstrom, A., Burkhardt, H. and Holmdahl, R., T cell recognition of carbohydrates on type II collagen. J. Exp. Med. 1994. 180: 745-749.
7. Haurum, J. S., Arsequell, G., Lellouch, A. C., Wong, S. Y., Dwek, R. A., McMichael, A. J. E. and Elliott, T., Recognition of carbohydrate by major histocompatibility complex class l-restricted, giycopeptide-specific cytotoxic T lymphocytes. J. Exp. Med. 1994.180: 739-744.
8. Jensen, T., Hansen, P., Galli-Stampino, L., Mouritsen, S., Frische, K. M., Meinjohanns, E., Meldal, M. and Werdelin, O., Carbohydrate and peptide specificity of MHC class ll-restricted T cell hybridomas raised against an O-glycosylated seif peptide. J. Immunol. 1997. 158: 3769-3778.
9. Kihlberg, J. and Elofsson, M., Solid-phase synthesis of glycopeptides: Immunological studies with T cell stimulating glycopeptides. Curr. Medicinal Chem. 1997. 4: 85-113. \
10. Chicz, R. M., Urban, R. G., Gorga, J. C., Vignali, D. A., Lane, W. S. and Strominger, J. L, Specificity and promiscuity among naturally processed peptides bound to HLA-DR alleles. J. Exp. Med. 1993.178: 27-47.
11. Chicz, R. M., Lane, W. S., Robinson, R. A., Trucco, M., Strominger, J. L. and Gorga, J. C., Self-peptides bound to the type I diabetes associated class II MHC molecules HLA-DQ1 and HLA-DQ8. Int. Immunol. 1994. 6:1639-1649.
12. Fremont, D. H., Hendrickson, W. A., Marrack, P. and Kappler, J., Structures of an MHC class II molecule with covalently bound single peptides. Science 1996. 272: 1001-1004.
13. Corthay, A., Bäcklund, J., Broddefalk, J., Michaelsson, E., Goldschmidt, T. J., Kihlberg, J. and Holmdahl, R., Epitope glycosylation plays a critical role for T cell recognition of type II collagen in collagen-induced arthritis. Eur. J. Immunol. 1998. 28: 2580-2590.
14. Zisman, E., Sela, M., Ben-Nun, A. and Mozes, E., Dichotomy between the T and the B cell epitopes of the synthetic polypeptide (T, G)-A-L. Eur. J. Immunol. 1994. 24: 2497-2505.
15. Pannetier, C., Cochet, M., Darche, S., Casrouge, A., Zoller, M. and Kourilsky, P., The sizes of the CDR3 hypervariable regions of the murine T-cell receptor beta chains vary as a function of the recombined germ-line segments. Proc. Nail. Acad.-'Sci. USA 1993. 90: 4319-4323.
16. Letourneur, F. and Malissen, B., Derivation of a T cell hybridoma variant deprived of functional T cell receptor alpha and beta chain transcripts reveals a nonfunctional alpha-mRNA of BW5147 origin. Eur. J. Immunol. 1989. 19:2269-2274.
17. Hsu, B. L., Donermeyer, D. L. and Allen, P. M., TCR recognition of the Hb(64-76)/l-Ek determinant: single conservative amino acid changes in the complementarity-determining region 3 dramatically alter antigen fine specificity. J. Immunol. 1996. 157: 2291-2298.
18. Candeias, S., Katz, J., Benoist, C., Mathis, D. and Haskins, K., Islet-specific T-cell clones from nonobese diabetic mice express heterogeneous T-cell receptors. Proc. Natl. Acad. Sei. USA 1991. 88: 6167-6170.
19. Davis, M. M. and Bjorkman, P. J., T-cell antigen receptor genes and T-cell recognition. Nature 1988. 34: 395-402.
20. Engel, I. and Hedrick, S. M., Site-directed mutations in the VDJ junctional region of a T cell receptor beta chain cause changes in antigenic peptide recognition. Cell 1988.54: 473-484.
21. Danska, J. S., Livingstone, A. M., Paragas, V., Ishihara, T. and Fathman, C. G., The presumptive CDR3 regions of both T cell receptor alpha and beta chains determine T cell specificity for myoglobin peptides. J. Exp. Med. 1990.172: 27-33.
22. Hedrick, S. M., Engel, I., McElligott, D. L., Fink, P. J., Hsu, M.-L., Hansburg, D. and Matis, L. A., Selection of amino acid sequences in the beta chain of the T cell antigen receptor. Science 1988. 239:1541-1544.
23. Enrich, E. W., Devaux, B., Rock, E. P., Jorgensen, J. L., Davis, M. M. and Chien, Y. H., T cell receptor interaction with peptide/major histocompatibility complex (MHC) and superantigen/MHC ligands is dominated by antigen. J. Exp. Med. 1993.178: 713-722.
24. Casanova, J. L., Martinen, F., Gournier, H., Barra, C., Pannetier, C., Regnault, A., Kourilsky, P., Cerottini, J. C. and Maryanski, J. L., T cell receptor selection by and recognition of two class I major histocompatibility complex-restricted antigenic peptides that differ at a single position. J. Exp. Med. 1993.177: 811-820.
25. Kelly, J. M., Sterry, S. J., Cose, S., Turner, S. J., Fecondo, J., Rodda, S., Fink, P. J. C. and Capone, F. ; :R., Identification of conserved T cell receptor CR3 resi_dues contacting known exposed peptide side chains from a major histocompatibility complex class l-bound determinant. Eur. J. Immunol. 1993. 23: 3318-3326.
26. Lai, M. Z., Jang, Y. J., Chen, L. K. and Getter, M. L., Restricted V-(D)-J junctional regions in the T cell response to lambda-repressor. Identification of residues critical for antigen recognition. J. Immunol. 1990. 144: 4851-4856.
27. Jorgensen, J. L., Esser, U., Fazekas B., Reay, P. A. and Davis, M. M., Mapping T-cell receptorpeptide contacts by variant peptide immunization of single-chain transgenics. Nature 1992. 355: 224-230.
28. Sant'Angelo, D. B., Waterbury, P. G., PrestonHurlburt, P., Yoon, S. T., Medzhitov, R., Hong, S.-C. and Janeway, Jr., C. A., The specificity and orientation of a TCR to its peptide-MHC class II ligands. Immunity 1996.4:367-376.
29. Davis, M. M., Boniface, J. J., Reich, Z., Lyons, D., Hampl, J., Arden, B. and Chien, Y.-Y., Ligand recognition by a T cell receptors. Annu. Rev. Immunol. 1998. 16: 523-544.
30. Garboczi, D. N., Ghosh, P., Utz, U., Fan, Q. R., Biddison, W. E. and Wiley, D. C., Structure of the complex between human T-cell receptor, viral peptide and HLAA2. Nature 1996. 384:134-141.
31. Garcia, K. C., Degano, M., Stanfield, R. L., Brunmark, A., Jackson, M. R., Peterson, P. A., Teyton, L. and Wilson, I. A., An alpha-beta T cell receptor structure at 2.5 A and its orientation in the TCR-MHC complex. Science 1996.274:209-219.
32. Ding, Y. H., Smith, K. J., Garboczi, D. N., Utz, U., Biddison, W. E. and Wiley, D. C., Two human T cell receptors bind in a similar diagonal mode to the HLA-A2/Tax peptide complex using different TCR amino acids. Immunity 1998. 8: 403-411.
33. Garcia, K. C., Degano, M., Pease, L. R., Huang, M., Peterson, P. A., Teyton, L. and Wilson, I. A., Structural basis of plasticity in T cell receptor recognition of a self peptide-MHC antigen. Science 1998. 279:1166-1172.
34. Koop, B. F., Wilson, R. K., Wang, K., Vernooij, B., Zallwer, D., Kuo, C. L., Seto, D. T., Toda, M. and Hood, L., Organization, structure, and function of 95kb of DNA spanning the murine T-celi receptor C alpha/C delta region. Genomics 1992.13:1209-1230.
35. Arden, B., Clark, S. P., Kabelitz, D. and Mak, T. W., Mouse T-cell receptor variable gene segment families. Immunogenetics 1995.42: 501-530.
36. Heath, W. R., Carbone, F. R., Bertolino, P., Kelly, J., Cose, S. and Miller, J. F., Expression of two T cell receptor alpha chains on the surface of normal murine T cells. Eur. J. Immunol. 1995. 25:1617-1623.
37. Hardardottir, F., Baron, J. L. and Janeway Jr., C. A., T cells with two functional antigen-specific receptors. Proc. Natl. Acad. Sei. USA 1995. 92: 354-358.
38. Padovan, E., Giachino, C., Cella, M., Valitutti, S., Acuto, O. and Lanzavecchia, A., Normal T lymphocytes express two different T cell receptor beta chains: implications for the mechanism of.àllelic exclusion. J. Exp. Med. 1995.181:1587-1591
39. Davodeau, F., Peyrat, M. A., Romagne, F., Necker, A., Hallet, M. M. and Vie, H. B. M., Dual T cell receptor beta chain expression on human T lymphocytes. J. Exp. Med. 1995.181:1391-1398.
40. Gascoigne, N. R., Chien, Y., Becker, D. M., Kavalér, J. and Davis, M. M., Genomic organization and sequence of T-cell receptor beta-chain constant- and joiningregion genes. Nature 1984. 310: 387-391.
41. Carson, R. T., Vignali, K. M., Woodland, D. L. and Vignali, D. A., T cell receptor recognition of MHC class IIbound peptide flanking residues enhances immunogenicity and results in altered TCR V region usage. Immunity 1997. 7: 387-399.
42. Lemieux, R. U., How water provides the impetus for molecular recognition in aqueous solution. Ace. Chem. Res. 1996. 29:373-380.
43. Bundle, D. R., Eichler, E., Gidney, M. A., Meldal, M., Ragauskas, A., Sigurskjold, B. W., Sinnott, B., Watson,-D. C., Yaguchi, M. and Young, N. M., Molecular recognition of a Salmonella trisaccharide epitope by monoclonal antibody Se155-4. Biochemistry 1994. 33: 5172-5182.
44. Stoffer, B., Aleshin, A. E., Firsov, L. M., Svensson, B. and Honzatko, R. B., Refined structure for the complex of D-gluco-dihydroacarbose with glucoamylase from Aspergillus awamori var. X100 to 2.2 A resolution: dual conformations for extended inhibitors bound to the active site of glucoamylase. FEES Lett. 1995. 358: 57-61.
45. Haurum, J. S., Tan, L, Arsequell, G., Frodsham, P., Lellouch, A. C., Moss, P. A. H., Dwek, R. A., McMichael, A. J. and Elliott, T., Peptide anchor residue glycosylation: effect on class I major histocompatibility complex binding and cytotoxic T lymphocyte recognition. Eur. J. Immunol. 1995. 25: 3270-3276.
46. Glithero, A., Tormo, J., Haurum, J. S., Arsequell, G., Valencia, G., Edwards, J., Springer, S., Townsend, A., Ya-Lan, P., Wormald, M., Dwek, R. A., Jones, E. Y. and Elliot, T., Crystal structures of two H-2Db/giycopeptide complexes suggest a molecular basis for CTL crossreactivity. Immunity 1999.10: 63-74.
47. Speir, J. A., Abdel-Motal, U. M., Jondal, M. and Wilson, I. A., Crystal structure of an MHC class I presented glycppeptide that generates carbohydrate-specific T cells. Immunity 1999.10: 51-61.
48. Springer, G. F., Immunoreactive T and Tn epitopes in cancer diagnosis, prognosis, and immunotherapy. J. Mol. Med. 1997. 75: 594-602.
49. Frische, K., Meldal, Werdelin, O., Mouritsen, S., Jensen, T., Galli-Stampino, L. and Bock, K., Multiple column synthesis of a library of T-cell stimulating Tnantigenic glycopeptide analogues for the molecular characterization of T-cell-glycan specificity. J. Peptide Sei. 1996.2:212-222.
50. White, J., Blackman, M., Bill, J., Kappler, J., Marrack, P., Gold, D. P. and Born, W., Two better cell lines for making hybridomas expressing specific T cell receptors. J. Immunol. 1989.143:1822-1825.
51. Bassam, B. J. and Caetano-Anolles, G., Automated "hot start" PCR using mineral oil and paraffin wax. Biotechniques 1993.14: 30-34.
52. Liu, Z. G. and Schwartz, L. M., An efficient method for blunt-end ligation of PCR products. Biotechniques 1992. 12: 28-30.