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Volumn 8, Issue , 2017, Pages

Massively parallel digital transcriptional profiling of single cells

(33)  Zheng, Grace X Y a   Terry, Jessica M a   Belgrader, Phillip a   Ryvkin, Paul a   Bent, Zachary W a   Wilson, Ryan a   Ziraldo, Solongo B a   Wheeler, Tobias D a   McDermott, Geoff P a   Zhu, Junjie a   Gregory, Mark T b   Shuga, Joe a   Montesclaros, Luz a   Underwood, Jason G a,c   Masquelier, Donald A a   Nishimura, Stefanie Y a   Schnall Levin, Michael a   Wyatt, Paul W a   Hindson, Christopher M a   Bharadwaj, Rajiv a   more..


Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; MESSENGER RNA; TRANSCRIPTOME;

EID: 85009446777     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms14049     Document Type: Article
Times cited : (3936)

References (42)
  • 1
    • 84878997106 scopus 로고    scopus 로고
    • Single-cell transcriptomics reveals bimodality in expression and splicing in immune cells
    • Shalek, A. K. , et al. Single-cell transcriptomics reveals bimodality in expression and splicing in immune cells. Nature 498, 236-240 (2013).
    • (2013) Nature , vol.498 , pp. 236-240
    • Shalek, A.K.1
  • 2
    • 84882582801 scopus 로고    scopus 로고
    • Single-cell gene expression analysis reveals genetic associations masked in whole-tissue experiments
    • Wills, Q. F. , et al. Single-cell gene expression analysis reveals genetic associations masked in whole-tissue experiments. Nat. Biotechnol. 31, 748-752 (2013).
    • (2013) Nat. Biotechnol , vol.31 , pp. 748-752
    • Wills, Q.F.1
  • 4
    • 84893905629 scopus 로고    scopus 로고
    • Massively parallel single-cell RNA-seq for marker-free decomposition of tissues into cell types
    • Jaitin, D. A. , et al. Massively parallel single-cell RNA-seq for marker-free decomposition of tissues into cell types. Science 343, 776-779 (2014).
    • (2014) Science , vol.343 , pp. 776-779
    • Jaitin, D.A.1
  • 5
    • 84922321862 scopus 로고    scopus 로고
    • Low-coverage single-cell mRNA sequencing reveals cellular heterogeneity and activated signaling pathways in developing cerebral cortex
    • Pollen, A. A. , et al. Low-coverage single-cell mRNA sequencing reveals cellular heterogeneity and activated signaling pathways in developing cerebral cortex. Nat. Biotechnol. 32, 1053-1058 (2014).
    • (2014) Nat. Biotechnol , vol.32 , pp. 1053-1058
    • Pollen, A.A.1
  • 7
    • 84929684999 scopus 로고    scopus 로고
    • Highly parallel genome-wide expression profiling of individual cells using nanoliter droplets
    • Macosko, E. Z. , et al. Highly parallel genome-wide expression profiling of individual cells using nanoliter droplets. Cell 161, 1202-1214 (2015).
    • (2015) Cell , vol.161 , pp. 1202-1214
    • MacOsko, E.Z.1
  • 8
    • 84929684998 scopus 로고    scopus 로고
    • Droplet barcoding for single-cell transcriptomics applied to embryonic stem cells
    • Klein, A. M. , et al. Droplet barcoding for single-cell transcriptomics applied to embryonic stem cells. Cell 161, 1187-1201 (2015).
    • (2015) Cell , vol.161 , pp. 1187-1201
    • Klein, A.M.1
  • 10
    • 84960894307 scopus 로고    scopus 로고
    • Haplotyping germline and cancer genomes with highthroughput linked-read sequencing
    • Zheng, G. X. , et al. Haplotyping germline and cancer genomes with highthroughput linked-read sequencing. Nat. Biotechnol. 34, 303-311 (2016).
    • (2016) Nat. Biotechnol , vol.34 , pp. 303-311
    • Zheng, G.X.1
  • 11
    • 84960087088 scopus 로고    scopus 로고
    • Health and population effects of rare gene knockouts in adult humans with related parents
    • Narasimhan, V. M. , et al. Health and population effects of rare gene knockouts in adult humans with related parents. Science 352, 474-477 (2016).
    • (2016) Science , vol.352 , pp. 474-477
    • Narasimhan, V.M.1
  • 12
    • 84966549638 scopus 로고    scopus 로고
    • A hybrid approach for de novo human genome sequence assembly and phasing
    • Mostovoy, Y. , et al. A hybrid approach for de novo human genome sequence assembly and phasing. Nat. Methods 13, 587-590 (2016).
    • (2016) Nat. Methods , vol.13 , pp. 587-590
    • Mostovoy, Y.1
  • 13
    • 81255175501 scopus 로고    scopus 로고
    • High-throughput droplet digital PCR system for absolute quantitation of DNA copy number
    • Hindson, B. J. , et al. High-throughput droplet digital PCR system for absolute quantitation of DNA copy number. Anal. Chem. 83, 8604-8610 (2011).
    • (2011) Anal. Chem , vol.83 , pp. 8604-8610
    • Hindson, B.J.1
  • 14
    • 84887109584 scopus 로고    scopus 로고
    • Accounting for technical noise in single-cell RNA-seq experiments
    • Brennecke, P. , et al. Accounting for technical noise in single-cell RNA-seq experiments. Nat. Methods 10, 1093-1095 (2013).
    • (2013) Nat. Methods , vol.10 , pp. 1093-1095
    • Brennecke, P.1
  • 15
    • 0034062083 scopus 로고    scopus 로고
    • Analysis of large-scale gene expression data
    • Sherlock, G. Analysis of large-scale gene expression data. Curr. Opin. Immunol. 12, 201-205 (2000).
    • (2000) Curr. Opin. Immunol , vol.12 , pp. 201-205
    • Sherlock, G.1
  • 16
    • 57249084011 scopus 로고    scopus 로고
    • Visualizing high-dimensional data using t-SNE
    • van der Maaten, L. J. P., Hinton, G. E Visualizing high-dimensional data using t-SNE. J. Mach. Learn. Res. 9, 2579-2605 (2008).
    • (2008) J. Mach. Learn. Res , vol.9 , pp. 2579-2605
    • Van Der Maaten, L.J.P.1    Hinton, G.E.2
  • 18
    • 33845878827 scopus 로고    scopus 로고
    • The CD94/NKG2 family of receptors: From molecules and cells to clinical relevance
    • Borrego, F., Masilamani, M., Marusina, A. I., Tang, X., Coligan, J. E The CD94/NKG2 family of receptors: from molecules and cells to clinical relevance. Immunol. Res. 35, 263-278 (2006).
    • (2006) Immunol. Res , vol.35 , pp. 263-278
    • Borrego, F.1    Masilamani, M.2    Marusina, A.I.3    Tang, X.4    Coligan, J.E.5
  • 20
    • 84896360122 scopus 로고    scopus 로고
    • S S100A8 and S100A9: DAMPs at the crossroads between innate immunity, traditional risk factors, and cardiovascular disease
    • Schiopu, A., Cotoi, O. S S100A8 and S100A9: DAMPs at the crossroads between innate immunity, traditional risk factors, and cardiovascular disease. Mediat. Inflamm. 2013, 828354 (2013).
    • (2013) Mediat. Inflamm. , pp. 828354
    • Schiopu, A.1    Cotoi, O.2
  • 21
    • 0027460515 scopus 로고
    • Characterization of a novel gene (NKG7) on human chromosome 19 that is expressed in natural killer cells and T cells
    • Turman, M. A., Yabe, T., McSherry, C., Bach, F. H., Houchins, J. P Characterization of a novel gene (NKG7) on human chromosome 19 that is expressed in natural killer cells and T cells. Hum. Immunol. 36, 34-40 (1993).
    • (1993) Hum. Immunol , vol.36 , pp. 34-40
    • Turman, M.A.1    Yabe, T.2    McSherry, C.3    Bach, F.H.4    Houchins, J.P.5
  • 22
    • 84933672236 scopus 로고    scopus 로고
    • The IL-23-IL-17 axis in inflammatory arthritis
    • Lubberts, E The IL-23-IL-17 axis in inflammatory arthritis. Nat. Rev. Rheumatol. 11, 562 (2015).
    • (2015) Nat. Rev. Rheumatol. , vol.11 , pp. 562
    • Lubberts, E.1
  • 23
    • 84928777722 scopus 로고    scopus 로고
    • Glucocorticoid-induced tumour necrosis factor receptorrelated protein: A key marker of functional regulatory T cells
    • Ronchetti, S. , et al. Glucocorticoid-induced tumour necrosis factor receptorrelated protein: a key marker of functional regulatory T cells. J. Immunol. Res. 2015, 171520 (2015).
    • (2015) J. Immunol. Res. , pp. 171520
    • Ronchetti, S.1
  • 24
    • 84864117109 scopus 로고    scopus 로고
    • Transcriptional regulator Id2 is required for the CD4 T cell immune response in the development of experimental autoimmune encephalomyelitis
    • Lin, Y. Y. , et al. Transcriptional regulator Id2 is required for the CD4 T cell immune response in the development of experimental autoimmune encephalomyelitis. J. Immunol. 189, 1400-1405 (2012).
    • (2012) J. Immunol , vol.189 , pp. 1400-1405
    • Lin, Y.Y.1
  • 25
    • 84896759705 scopus 로고    scopus 로고
    • Serum IgE clearance is facilitated by human FcepsilonRI internalization
    • Greer, A. M. , et al. Serum IgE clearance is facilitated by human FcepsilonRI internalization. J. Clin. Invest. 124, 1187-1198 (2014).
    • (2014) J. Clin. Invest , vol.124 , pp. 1187-1198
    • Greer, A.M.1
  • 26
    • 84871822108 scopus 로고    scopus 로고
    • Identification of lineage relationships and novel markers of blood and skin human dendritic cells
    • Harman, A. N. , et al. Identification of lineage relationships and novel markers of blood and skin human dendritic cells. J. Immunol. 190, 66-79 (2013).
    • (2013) J. Immunol , vol.190 , pp. 66-79
    • Harman, A.N.1
  • 28
    • 85009464193 scopus 로고    scopus 로고
    • Seattle Cancer Care Alliance
    • Seattle Cancer Care Alliance. Chimerism testing/engraftment analysis. http://www. seattlecca. org/healthcare-professionals/clinical-labs/clinicalimmunogenetics-laboratory/chimerism-testing (2016).
    • (2016) Chimerism Testing/engraftment Analysis.
  • 29
    • 84902668801 scopus 로고    scopus 로고
    • Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma
    • Patel, A. P. , et al. Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma. Science 344, 1396-1401 (2014).
    • (2014) Science , vol.344 , pp. 1396-1401
    • Patel, A.P.1
  • 30
    • 84963614956 scopus 로고    scopus 로고
    • Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq
    • Tirosh, I. , et al. Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq. Science 352, 189-196 (2016).
    • (2016) Science , vol.352 , pp. 189-196
    • Tirosh, I.1
  • 31
    • 84914706587 scopus 로고    scopus 로고
    • Single-cell analyses of transcriptional heterogeneity during drug tolerance transition in cancer cells by RNA sequencing
    • Lee, M. C. , et al. Single-cell analyses of transcriptional heterogeneity during drug tolerance transition in cancer cells by RNA sequencing. Proc. Natl. Acad. Sci. USA 111, E4726-E4735 (2014).
    • (2014) Proc. Natl. Acad. Sci. USA , vol.111 , pp. E4726-E4735
    • Lee, M.C.1
  • 32
    • 84937573360 scopus 로고    scopus 로고
    • Single-cell mRNA sequencing identifies subclonal heterogeneity in anti-cancer drug responses of lung adenocarcinoma cells
    • Kim, K. T. , et al. Single-cell mRNA sequencing identifies subclonal heterogeneity in anti-cancer drug responses of lung adenocarcinoma cells. Genome Biol. 16, 127 (2015).
    • (2015) Genome Biol , vol.16 , pp. 127
    • Kim, K.T.1
  • 33
    • 70349256226 scopus 로고    scopus 로고
    • The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: Rationale and important changes
    • Vardiman, J. W. , et al. The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes. Blood 114, 937-951 (2009).
    • (2009) Blood , vol.114 , pp. 937-951
    • Vardiman, J.W.1
  • 34
    • 37349044981 scopus 로고    scopus 로고
    • A microfluidic processor for gene expression profiling of single human embryonic stem cells
    • Zhong, J. F. , et al. A microfluidic processor for gene expression profiling of single human embryonic stem cells. Lab Chip 8, 68-74 (2008).
    • (2008) Lab Chip , vol.8 , pp. 68-74
    • Zhong, J.F.1
  • 35
    • 84871809302 scopus 로고    scopus 로고
    • STAR: Ultrafast universal RNA-seq aligner
    • Dobin, A. , et al. STAR: ultrafast universal RNA-seq aligner. Bioinformatics 29, 15-21 (2013).
    • (2013) Bioinformatics , vol.29 , pp. 15-21
    • Dobin, A.1
  • 37
    • 85009481901 scopus 로고    scopus 로고
    • Barnes-Hut-SNE Preprint at arXiv: 1301. 3342 [cs. LG]
    • van der Maaten, L. Barnes-Hut-SNE Preprint at arXiv:1301. 3342 [cs. LG] (2013).
    • (2013)
    • Van Der Maaten, L.1
  • 38
    • 0034354410 scopus 로고    scopus 로고
    • Dealing with label switching in mixture models
    • Stephens, M. Dealing with label switching in mixture models. J. R. Stat. Soc. Ser. B 62, 795-809 (2000).
    • (2000) J. R. Stat. Soc. Ser. B , vol.62 , pp. 795-809
    • Stephens, M.1
  • 39
    • 84904308624 scopus 로고    scopus 로고
    • Significance of CD71 expression by flow cytometry in diagnosis of acute leukemia
    • Liu, Q. , et al. Significance of CD71 expression by flow cytometry in diagnosis of acute leukemia. Leuk. Lymphoma 55, 892-898 (2014).
    • (2014) Leuk. Lymphoma , vol.55 , pp. 892-898
    • Liu, Q.1
  • 40
    • 78651486442 scopus 로고    scopus 로고
    • Densely interconnected transcriptional circuits control cell states in human hematopoiesis
    • Novershtern, N. , et al. Densely interconnected transcriptional circuits control cell states in human hematopoiesis. Cell 144, 296-309 (2011).
    • (2011) Cell , vol.144 , pp. 296-309
    • Novershtern, N.1
  • 41
    • 84897967621 scopus 로고    scopus 로고
    • Molecular mechanisms of cell death: Central implication of ATP synthase in mitochondrial permeability transition
    • Bonora, M. , et al. Molecular mechanisms of cell death: central implication of ATP synthase in mitochondrial permeability transition. Oncogene 34, 1475-1486 (2015).
    • (2015) Oncogene , vol.34 , pp. 1475-1486
    • Bonora, M.1
  • 42
    • 84929385369 scopus 로고    scopus 로고
    • IL8-CXCR2 pathway inhibition as a therapeutic strategy against MDS and AML stem cells
    • Schinke, C. , et al. IL8-CXCR2 pathway inhibition as a therapeutic strategy against MDS and AML stem cells. Blood 125, 3144-3152 (2015).
    • (2015) Blood , vol.125 , pp. 3144-3152
    • Schinke, C.1


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