-
1
-
-
33847629171
-
Translational mini-review series on type 1 diabetes: Systematic analysis of T cell epitopes in autoimmune diabetes
-
Di Lorenzo, T. P., Peakman, M., Roep, B. O. Translational mini-review series on type 1 diabetes: Systematic analysis of T cell epitopes in autoimmune diabetes. Clin. Exp. Immunol. 148, 1-16 (2007).
-
(2007)
Clin. Exp. Immunol.
, vol.148
, pp. 1-16
-
-
Di Lorenzo, T.P.1
Peakman, M.2
Roep, B.O.3
-
2
-
-
26444528560
-
Tetramer analysis of human autoreactive CD4-positive T cells
-
Nepom, G. T. Tetramer analysis of human autoreactive CD4-positive T cells. Adv. Immunol. 88, 51-71 (2005).
-
(2005)
Adv. Immunol.
, vol.88
, pp. 51-71
-
-
Nepom, G.T.1
-
3
-
-
77951983004
-
Simultaneous detection of circulating autoreactive CD8+ T-cells specific for different islet cell-associated epitopes using combinatorial MHC multimers
-
Velthuis, J. H. et al. Simultaneous detection of circulating autoreactive CD8+ T-cells specific for different islet cell-associated epitopes using combinatorial MHC multimers. Diabetes 59, 1721-1730 (2010).
-
(2010)
Diabetes
, vol.59
, pp. 1721-1730
-
-
Velthuis, J.H.1
-
4
-
-
84908632192
-
Blood and islet phenotypes indicate immunological heterogeneity in type 1 diabetes
-
Arif, S. et al. Blood and islet phenotypes indicate immunological heterogeneity in type 1 diabetes. Diabetes 63, 3835-3845 (2014).
-
(2014)
Diabetes
, vol.63
, pp. 3835-3845
-
-
Arif, S.1
-
5
-
-
84962422694
-
Insulitis and-cell mass in the natural history of type 1 diabetes
-
Campbell-Thompson, M. et al. Insulitis and-cell mass in the natural history of type 1 diabetes. Diabetes 65, 719-731 (2016).
-
(2016)
Diabetes
, vol.65
, pp. 719-731
-
-
Campbell-Thompson, M.1
-
6
-
-
84885707244
-
The diagnosis of insulitis in human type 1 diabetes
-
Campbell-Thompson, M. L. et al. The diagnosis of insulitis in human type 1 diabetes. Diabetologia 56, 2541-2543 (2013).
-
(2013)
Diabetologia
, vol.56
, pp. 2541-2543
-
-
Campbell-Thompson, M.L.1
-
7
-
-
0022475906
-
The histopathology of the pancreas in type 1 (insulin-dependent) diabetes mellitus: A 25-year review of deaths in patients under 20 years of age in the United Kingdom
-
Foulis, A. K., Liddle, C. N., Farquharson, M. A., Richmond, J. A., Weir, R. S. The histopathology of the pancreas in type 1 (insulin-dependent) diabetes mellitus: a 25-year review of deaths in patients under 20 years of age in the United Kingdom. Diabetologia 29, 267-274 (1986).
-
(1986)
Diabetologia
, vol.29
, pp. 267-274
-
-
Foulis, A.K.1
Liddle, C.N.2
Farquharson, M.A.3
Richmond, J.A.4
Weir, R.S.5
-
8
-
-
76549198972
-
Pathologic anatomy of the pancreas in juvenile diabetes mellitus
-
Gepts, W. Pathologic anatomy of the pancreas in juvenile diabetes mellitus. Diabetes 14, 619-633 (1965).
-
(1965)
Diabetes
, vol.14
, pp. 619-633
-
-
Gepts, W.1
-
9
-
-
84856825977
-
Demonstration of islet-autoreactive CD8 T cells in insulitic lesions from recent onset and long-term type 1 diabetes patients
-
Coppieters, K. T. et al. Demonstration of islet-autoreactive CD8 T cells in insulitic lesions from recent onset and long-term type 1 diabetes patients. J. Exp. Med. 209, 51-60 (2012).
-
(2012)
J. Exp. Med.
, vol.209
, pp. 51-60
-
-
Coppieters, K.T.1
-
10
-
-
84920024469
-
Proinsulin-specific, HLA-DQ8, HLA-DQ8-transdimer-restricted CD4+ T cells infiltrate islets in type 1 diabetes
-
Pathiraja, V. et al. Proinsulin-specific, HLA-DQ8, HLA-DQ8-transdimer-restricted CD4+ T cells infiltrate islets in type 1 diabetes. Diabetes 64, 172-182 (2015).
-
(2015)
Diabetes
, vol.64
, pp. 172-182
-
-
Pathiraja, V.1
-
11
-
-
79953189382
-
TCR bias of in vivo expanded T cells in pancreatic islets and spleen at the onset in human type 1 diabetes
-
Codina-Busqueta, E. et al. TCR bias of in vivo expanded T cells in pancreatic islets and spleen at the onset in human type 1 diabetes. J. Immunol. 186, 3787-3797 (2011).
-
(2011)
J. Immunol.
, vol.186
, pp. 3787-3797
-
-
Codina-Busqueta, E.1
-
12
-
-
0027959188
-
Evidence for superantigen involvement in insulin-dependent diabetes mellitus aetiology
-
Conrad, B. et al. Evidence for superantigen involvement in insulin-dependent diabetes mellitus aetiology. Nature 371, 351-355 (1994).
-
(1994)
Nature
, vol.371
, pp. 351-355
-
-
Conrad, B.1
-
13
-
-
0027361654
-
Mononuclear cell infiltration and its relation to the expression of major histocompatibility complex antigens and adhesion molecules in pancreas biopsy specimens from newly diagnosed insulin-dependent diabetes mellitus patients
-
Itoh, N. et al. Mononuclear cell infiltration and its relation to the expression of major histocompatibility complex antigens and adhesion molecules in pancreas biopsy specimens from newly diagnosed insulin-dependent diabetes mellitus patients. J. Clin. Invest. 92, 2313-2322 (1993).
-
(1993)
J. Clin. Invest.
, vol.92
, pp. 2313-2322
-
-
Itoh, N.1
-
14
-
-
84957437395
-
Insulitis and characterisation of infiltrating T cells in surgical pancreatic tail resections from patients at onset of type 1 diabetes
-
Krogvold, L. et al. Insulitis and characterisation of infiltrating T cells in surgical pancreatic tail resections from patients at onset of type 1 diabetes. Diabetologia 59, 492-501 (2016).
-
(2016)
Diabetologia
, vol.59
, pp. 492-501
-
-
Krogvold, L.1
-
15
-
-
79251634951
-
The pancreas in human type 1 diabetes
-
Rowe, P. A., Campbell-Thompson, M. L., Schatz, D. A., Atkinson, M. A. The pancreas in human type 1 diabetes. Semin. Immunopathol. 33, 29-43 (2011).
-
(2011)
Semin. Immunopathol.
, vol.33
, pp. 29-43
-
-
Rowe, P.A.1
Campbell-Thompson, M.L.2
Schatz, D.A.3
Atkinson, M.A.4
-
16
-
-
84872316562
-
Recognition of self and altered self by T cells in autoimmunity and allergy
-
Yin, L. et al. Recognition of self and altered self by T cells in autoimmunity and allergy. Protein Cell 4, 8-16 (2013).
-
(2013)
Protein Cell
, vol.4
, pp. 8-16
-
-
Yin, L.1
-
17
-
-
84924932110
-
Biological relevance of citrullinations: Diagnostic, prognostic and therapeutic options
-
Gudmann, N. S., Hansen, N. U., Jensen, A. C., Karsdal, M. A., Siebuhr, A. S. Biological relevance of citrullinations: diagnostic, prognostic and therapeutic options. Autoimmunity 48, 73-79 (2015).
-
(2015)
Autoimmunity
, vol.48
, pp. 73-79
-
-
Gudmann, N.S.1
Hansen, N.U.2
Jensen, A.C.3
Karsdal, M.A.4
Siebuhr, A.S.5
-
18
-
-
82955250010
-
Celiac disease and transglutaminase 2: A model for posttranslational modification of antigens and HLA association in the pathogenesis of autoimmune disorders
-
Sollid, L. M., Jabri, B. Celiac disease and transglutaminase 2: a model for posttranslational modification of antigens and HLA association in the pathogenesis of autoimmune disorders. Curr. Opin. Immunol. 23, 732-738 (2011).
-
(2011)
Curr. Opin. Immunol.
, vol.23
, pp. 732-738
-
-
Sollid, L.M.1
Jabri, B.2
-
19
-
-
84870323723
-
Diabetogenic T-cell clones recognize an altered peptide of chromogranin A
-
Delong, T. et al. Diabetogenic T-cell clones recognize an altered peptide of chromogranin A. Diabetes 61, 3239-3246 (2012).
-
(2012)
Diabetes
, vol.61
, pp. 3239-3246
-
-
Delong, T.1
-
20
-
-
27744524215
-
The insulin A-chain epitope recognized by human T cells is posttranslationally modified
-
Mannering, S. I. et al. The insulin A-chain epitope recognized by human T cells is posttranslationally modified. J. Exp. Med. 202, 1191-1197 (2005).
-
(2005)
J. Exp. Med.
, vol.202
, pp. 1191-1197
-
-
Mannering, S.I.1
-
21
-
-
84942083843
-
T cell epitopes and post-translationally modified epitopes in type 1 diabetes
-
McGinty, J. W., Marré, M. L., Bajzik, V., Piganelli, J. D., James, E. A. T cell epitopes and post-translationally modified epitopes in type 1 diabetes. Curr. Diab. Rep. 15, 90 (2015).
-
(2015)
Curr. Diab. Rep.
, vol.15
, pp. 90
-
-
McGinty, J.W.1
Marré, M.L.2
Bajzik, V.3
Piganelli, J.D.4
James, E.A.5
-
22
-
-
84921919130
-
Citrullinated glucose-regulated protein 78 is an autoantigen in type 1 diabetes
-
Rondas, D. et al. Citrullinated glucose-regulated protein 78 is an autoantigen in type 1 diabetes. Diabetes 64, 573-586 (2015).
-
(2015)
Diabetes
, vol.64
, pp. 573-586
-
-
Rondas, D.1
-
23
-
-
84946495260
-
Antibodies to post-translationally modified insulin in type 1 diabetes
-
Strollo, R. et al. Antibodies to post-translationally modified insulin in type 1 diabetes. Diabetologia 58, 2851-2860 (2015).
-
(2015)
Diabetologia
, vol.58
, pp. 2851-2860
-
-
Strollo, R.1
-
24
-
-
84891816614
-
Posttranslational modification of HLA-DQ binding islet autoantigens in type 1 diabetes
-
van Lummel, M. et al. Posttranslational modification of HLA-DQ binding islet autoantigens in type 1 diabetes. Diabetes 63, 237-247 (2014).
-
(2014)
Diabetes
, vol.63
, pp. 237-247
-
-
Van Lummel, M.1
-
25
-
-
84906661993
-
Recognition of posttranslationally modified GAD65 epitopes in subjects with type 1 diabetes
-
McGinty, J. W. et al. Recognition of posttranslationally modified GAD65 epitopes in subjects with type 1 diabetes. Diabetes 63, 3033-3040 (2014).
-
(2014)
Diabetes
, vol.63
, pp. 3033-3040
-
-
McGinty, J.W.1
-
26
-
-
84978852701
-
Human islets and dendritic cells generate post-translationally modified islet autoantigens
-
McLaughlin, R. J. et al. Human islets and dendritic cells generate post-translationally modified islet autoantigens. Clin. Exp. Immunol. 185, 133-140 (2016).
-
(2016)
Clin. Exp. Immunol.
, vol.185
, pp. 133-140
-
-
McLaughlin, R.J.1
-
27
-
-
84962406592
-
Discovery of a selective islet peptidome presented by the highest-risk HLA-DQ8trans molecule
-
van Lummel, M. et al. Discovery of a selective islet peptidome presented by the highest-risk HLA-DQ8trans molecule. Diabetes 65, 732-741 (2016).
-
(2016)
Diabetes
, vol.65
, pp. 732-741
-
-
Van Lummel, M.1
-
28
-
-
84957922058
-
Pathogenic CD4 T cells in type 1 diabetes recognize epitopes formed by peptide fusion
-
Delong, T. et al. Pathogenic CD4 T cells in type 1 diabetes recognize epitopes formed by peptide fusion. Science 351, 711-714 (2016).
-
(2016)
Science
, vol.351
, pp. 711-714
-
-
Delong, T.1
-
29
-
-
67349268443
-
Pancreatic beta cell function persists in many patients with chronic type 1 diabetes, but is not dramatically improved by prolonged immunosuppression and euglycaemia from a beta cell allograft
-
Liu, E. H. et al. Pancreatic beta cell function persists in many patients with chronic type 1 diabetes, but is not dramatically improved by prolonged immunosuppression and euglycaemia from a beta cell allograft. Diabetologia 52, 1369-1380 (2009).
-
(2009)
Diabetologia
, vol.52
, pp. 1369-1380
-
-
Liu, E.H.1
-
30
-
-
0021873134
-
Recurrent diabetes mellitus in the pancreas iso-and allograft A light and electron microscopic and immunohistochemical analysis of four cases
-
Sibley, R. K., Sutherland, D. E., Goetz, F., Michael, A. F. Recurrent diabetes mellitus in the pancreas iso-and allograft. A light and electron microscopic and immunohistochemical analysis of four cases. Lab. Invest. 53, 132-144 (1985).
-
(1985)
Lab. Invest.
, vol.53
, pp. 132-144
-
-
Sibley, R.K.1
Sutherland, D.E.2
Goetz, F.3
Michael, A.F.4
-
31
-
-
77951168859
-
Recurrence of type 1 diabetes after simultaneous pancreas-kidney transplantation, despite immunosuppression, is associated with autoantibodies and pathogenic autoreactive CD4 T-cells
-
Vendrame, F. et al. Recurrence of type 1 diabetes after simultaneous pancreas-kidney transplantation, despite immunosuppression, is associated with autoantibodies and pathogenic autoreactive CD4 T-cells. Diabetes 59, 947-957 (2010).
-
(2010)
Diabetes
, vol.59
, pp. 947-957
-
-
Vendrame, F.1
-
32
-
-
84962409093
-
Current concepts on the pathogenesis of type 1 diabetes-considerations for attempts to prevent and reverse the disease
-
Atkinson, M. A., von Herrath, M., Powers, A. C., Clare-Salzler, M. Current concepts on the pathogenesis of type 1 diabetes-considerations for attempts to prevent and reverse the disease. Diabetes Care 38, 979-988 (2015).
-
(2015)
Diabetes Care
, vol.38
, pp. 979-988
-
-
Atkinson, M.A.1
Von Herrath, M.2
Powers, A.C.3
Clare-Salzler, M.4
-
33
-
-
84872018209
-
Recent lessons learned from prevention and recent-onset type 1 diabetes immunotherapy trials
-
Staeva, T. P., Chatenoud, L., Insel, R., Atkinson, M. A. Recent lessons learned from prevention and recent-onset type 1 diabetes immunotherapy trials. Diabetes 62, 9-17 (2013).
-
(2013)
Diabetes
, vol.62
, pp. 9-17
-
-
Staeva, T.P.1
Chatenoud, L.2
Insel, R.3
Atkinson, M.A.4
-
34
-
-
84864088882
-
Isolation of human islets for autologous islet transplantation in children and adolescents with chronic pancreatitis
-
Bottino, R. et al. Isolation of human islets for autologous islet transplantation in children and adolescents with chronic pancreatitis. J. Transplant. 2012, 642787 (2012).
-
(2012)
J. Transplant.
, pp. 642787
-
-
Bottino, R.1
-
35
-
-
84856689283
-
Islet-enriched gene expression and glucose-induced insulin secretion in human and mouse islets
-
Dai, C. et al. Islet-enriched gene expression and glucose-induced insulin secretion in human and mouse islets. Diabetologia 55, 707-718 (2012).
-
(2012)
Diabetologia
, vol.55
, pp. 707-718
-
-
Dai, C.1
-
36
-
-
84942346225
-
Novel observations from next-generation RNA sequencing of highly purified human adult and fetal islet cell subsets
-
Blodgett, D. M. et al. Novel observations from next-generation RNA sequencing of highly purified human adult and fetal islet cell subsets. Diabetes 64, 3172-3181 (2015).
-
(2015)
Diabetes
, vol.64
, pp. 3172-3181
-
-
Blodgett, D.M.1
-
37
-
-
84863998008
-
Residual methylprednisolone suppresses human T-cell responses to spleen, but not islet, extracts from deceased organ donors
-
Joffe, M. et al. Residual methylprednisolone suppresses human T-cell responses to spleen, but not islet, extracts from deceased organ donors. Int. Immunol. 24, 447-453 (2012).
-
(2012)
Int. Immunol.
, vol.24
, pp. 447-453
-
-
Joffe, M.1
-
38
-
-
77954277549
-
Beta-cell replication is increased in donor organs from young patients after prolonged life support
-
In't Veld, P. et al. Beta-cell replication is increased in donor organs from young patients after prolonged life support. Diabetes 59, 1702-1708 (2010).
-
(2010)
Diabetes
, vol.59
, pp. 1702-1708
-
-
In'T Veld, P.1
-
39
-
-
84908635248
-
Increased immune cell infiltration of the exocrine pancreas: A possible contribution to the pathogenesis of type 1 diabetes
-
Rodriguez-Calvo, T., Ekwall, O., Amirian, N., Zapardiel-Gonzalo, J., von Herrath, M. G. Increased immune cell infiltration of the exocrine pancreas: a possible contribution to the pathogenesis of type 1 diabetes. Diabetes 63, 3880-3890 (2014).
-
(2014)
Diabetes
, vol.63
, pp. 3880-3890
-
-
Rodriguez-Calvo, T.1
Ekwall, O.2
Amirian, N.3
Zapardiel-Gonzalo, J.4
Von Herrath, M.G.5
-
40
-
-
57249095832
-
Protein kinase inhibitors substantially improve the physical detection of T-cells with peptide-MHC tetramers
-
Lissina, A. et al. Protein kinase inhibitors substantially improve the physical detection of T-cells with peptide-MHC tetramers. J. Immunol. Methods 340, 11-24 (2009).
-
(2009)
J. Immunol. Methods
, vol.340
, pp. 11-24
-
-
Lissina, A.1
|