Immunosequencing identifies signatures of cytomegalovirus exposure history and HLA-mediated effects on the T cell repertoire

Nature Genetics

Volumn 49, Issue 5, 2017, Pages 659-665

  Emerson, Ryan O ^a   DeWitt, William S ^a,b   Vignali, Marissa ^a   Gravley, Jenna ^b   Hu, Joyce K ^a   Osborne, Edward J ^a   Desmarais, Cindy ^a   Klinger, Mark ^a   Carlson, Christopher S ^b   Hansen, John A ^b   Rieder, Mark ^a   Robins, Harlan S ^a,b  

^a ADAPTIVE BIOTECHNOLOGIES   (United States)

^b USA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HLA A ANTIGEN; HLA B ANTIGEN; T LYMPHOCYTE RECEPTOR BETA CHAIN; EPITOPE; HLA ANTIGEN; LYMPHOCYTE ANTIGEN RECEPTOR;

ADOLESCENT; ADULT; ALLELE; ARTICLE; CHILD; COHORT ANALYSIS; CONTROLLED STUDY; CYTOMEGALOVIRUS INFECTION; EXPOSURE; FEMALE; HLA TYPING; HUMAN; IMMUNOSEQUENCING; IN VITRO STUDY; MALE; MEMORY T LYMPHOCYTE; MIDDLE AGED; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY; SEQUENCE ANALYSIS; T LYMPHOCYTE; ALGORITHM; BIOLOGICAL MODEL; CYTOMEGALOVIRUS; GENETICS; HIGH THROUGHPUT SEQUENCING; HISTOCOMPATIBILITY TEST; HOST PATHOGEN INTERACTION; IMMUNOLOGY; METABOLISM; PHYSIOLOGY; PROCEDURES; REPRODUCIBILITY; VIROLOGY;

ALGORITHMS; COHORT STUDIES; CYTOMEGALOVIRUS; EPITOPES, T-LYMPHOCYTE; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HISTOCOMPATIBILITY TESTING; HLA ANTIGENS; HLA-A ANTIGENS; HLA-B ANTIGENS; HOST-PATHOGEN INTERACTIONS; HUMANS; MODELS, IMMUNOLOGICAL; RECEPTORS, ANTIGEN, T-CELL; REPRODUCIBILITY OF RESULTS; T-LYMPHOCYTES;

EID: 85016925751     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng.3822     Document Type: Article

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