Psoriatic arthritis joint fluids are characterized by CD8 and CD4 T cell clonal expansions that appear antigen driven

Journal of Immunology

Volumn 166, Issue 4, 2001, Pages 2878-2886

  Costello, P J ^a   Winchester, R J ^a   Curran, S A ^a   Peterson, K S ^a   Kane, D J ^a   Bresnihan, B ^a   FitzGerald, O M ^a  

^a ST VINCENT S UNIVERSITY HOSPITAL   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; T LYMPHOCYTE RECEPTOR;

AMINO ACID SEQUENCE; ARTICLE; BLOOD; CLINICAL ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; LYMPHOCYTE CLONE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PSORIATIC ARTHRITIS; SYNOVIAL FLUID LEVEL; SYNOVITIS; T LYMPHOCYTE SUBPOPULATION;

EID: 0035865217     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.166.4.2878     Document Type: Article

References (55)

1. Cyclosporin A in psoriatic arthritis: An open study
2. Psoriatic arthritis - Review of current concepts
3. Psoriatic arthritis
4. Cytokine and genetic regulation of psoriasis
5. Response of psoriasis to a lymphocyte-selective toxin (DAB389IL-2) suggests a primary immune, but not keratinocyte, pathogenic basis
6. T cell derived cytokines in psoriatic arthritis synovial fluids
7. Psoriatic arthritis
8. + T lymphocytes in psoriatic arthritis
9. Association between HLA-BW38 and peripheral psoriatic arthritis
10. Psoriatic arthritis: A clinical, immunologic and HLA study of 100 patients
11. HLA-Bw38 and 39 in psoriatic arthritis: Relationships and implications for peripheral and axial involvement
12. The role of HLA antigens as indicators of disease progression in psoriatic arthritis: Multivariate relative risk model
13. Acquired immunodeficiency syndrome-associated psoriasis and Reiter's syndrome
14. The co-occurrence of Reiter's syndrome and acquired immunodeficiency
15. Histocompatibility alloantigens in psoriasis and psoriatic arthritis: Evidence for the influence of multiple genes in the major histocompatibility complex
16. HLA markers and progression in psoriatic arthritis
17. Analysis of HLA class II and TAP alleles in Japanese patients with psoriasis vulgaris
18. Linked help in the cytotoxic T-cell response revealed by adoptive transfer
19. + T-helper and a T-killer cell
20. Antigen organization regulates cluster formation and induction of cytotoxic T lymphocytes by helper T cell subsets
21. Mapping T-cell receptor-peptide contacts by variant peptide immunization of single-chain transgenics
22. Specific T cell recognition of minimally homologous peptides: Evidence for multiple endogenous ligands
23. Recognition surfaces of MHC class I
24. The presumptive CDR3 regions of both T cell receptor α and β chains determine T cell specificity for myoglobin peptides
25. Sequence analysis of the human α β T-cell receptor CDR3 region
26. + subset in normal human subjects
27. + T cell clones in elderly humans
28. The sizes of the CDR3 hypervariable regions of the murine T-cell receptor β chains vary as a function of the recombined germ-line segments
29. Circulating T cell repertoire complexity in normal individuals and bone marrow recipients analyzed by CDR3 size spectratyping: Correlation with immune status
30. Molecular analysis of T cell repertoires: Spectratypes generated by multiplex polymerase chain reaction and evaluated by radioactivity or fluorescence
31. Characterization of the primary structure of T cell receptor β chains in cells infiltrating the salivary gland in the sicca syndrome of HIV-1 infection: Evidence of Ag-driven clonal selection suggested by restricted combinations of Vβ Jβ gene segment usage and shared somatically encoded amino acid residues
32. Extensive conservation of α and β chains of the human T-cell antigen receptor recognizing HLA-A2 and influenza A matrix peptide
33. Structural basis of plasticity in T cell receptor recognition of a self peptide-MHC antigen
34. + T-cells in psoriatic arthritis appears antigen-driven
35. Human T-cell receptor gene nomenclature
36. Human T-cell receptor variable gene segment families
37. Oligoclonality of tumor-infiltrating lymphocytes from human melanomas
38. + T-cell population: Analysis using a multiplex PCR assay for CDR3 length
39. Usage of human T-cell receptor Vβ,Jβ, Cβ, and V α gene segments is not proportional to gene number
40. + repertoire during antiviral therapy
41. Common intra-articular T cell expansions in patients with reactive arthritis: Identical β-chain junctional sequences and cytotoxicity toward HLA-B27
42. Clonal characteristics of T cell infiltrates in skin and synovium of patients with psoriatic arthritis
43. + T cells in rheumatoid arthritis
44. + T cell populations prepared directly from rheumatoid synovium
45. HLA-dependent peripheral T cell receptor (TCR) repertoire formation and its modification by rheumatoid arthritis (RA)
46. Perturbation of the T cell repertoire in rheumatoid arthritis
47. + T cell clones in the synovial fluid of patients with rheumatoid arthritis
48. Aberrations in the primary T-cell receptor repertoire as a predisposition for synovial inflammation in rheumatoid arthritis
49. + T cell population of rheumatoid arthritis patients
50. +) T cells in patients with rheumatoid arthritis
51. TCR β spectratyping in RA: Evidence of clonal expansions in peripheral blood lymphocytes
52. Psoriatic arthritis and the spectrum of syndromes related to the SAPHO (synovitis, acne, pustulosis, hyperostosis, and osteitis) syndrome
53. Structural features of autoreactive TCR that determine the degree of degeneracy in peptide recognition
54. The T cell repertoire against cryptic self determinants and its involvement in autoimmunity and cancer