-
2
-
-
84875432419
-
Type 1 diabetes: Translating mechanistic observations into effective clinical outcomes
-
Herold KC, Vignali DAA, Cooke A, Bluestone JA. Type 1 diabetes: translating mechanistic observations into effective clinical outcomes. Nature Rev 2013; 13:243-256.
-
(2013)
Nature Rev
, vol.13
, pp. 243-256
-
-
Herold, K.C.1
Daa, V.2
Cooke, A.3
Bluestone, J.A.4
-
3
-
-
84888439466
-
Immune mechanisms in type 1 diabetes
-
Wallberg M, Cooke A. Immune mechanisms in type 1 diabetes. Trends Immunol 2013; 34:583-591.
-
(2013)
Trends Immunol
, vol.34
, pp. 583-591
-
-
Wallberg, M.1
Cooke, A.2
-
4
-
-
79960088916
-
Insulitis in human type 1 diabetes: The quest for an elusive lesion
-
Int Veld P. Insulitis in human type 1 diabetes: the quest for an elusive lesion. Islets 2011; 3:131-138.
-
(2011)
Islets
, vol.3
, pp. 131-138
-
-
Int Veld, P.1
-
5
-
-
84930791607
-
Insulitis in human type 1 diabetes: A comparison between patients and animal models
-
Int Veld P. Insulitis in human type 1 diabetes: a comparison between patients and animal models. Semin Immunopathol 2014; 36:569-579.
-
(2014)
Semin Immunopathol
, vol.36
, pp. 569-579
-
-
Int Veld, P.1
-
6
-
-
76549198972
-
Pathologic anatomy of the pancreas in juvenile diabetes mellitus
-
Gepts W. Pathologic anatomy of the pancreas in juvenile diabetes mellitus. Diabetes 1965; 14:619-633.
-
(1965)
Diabetes
, vol.14
, pp. 619-633
-
-
Gepts, W.1
-
8
-
-
84908632192
-
Blood and islet phenotypes indicate immunological heterogeneity in type 1 diabetes
-
Asif S, Leete P, Nguyen V, et al. Blood and islet phenotypes indicate immunological heterogeneity in type 1 diabetes. Diabetes 2014; 63:3835-3845.
-
(2014)
Diabetes
, vol.63
, pp. 3835-3845
-
-
Asif, S.1
Leete, P.2
Nguyen, V.3
-
9
-
-
84896080372
-
Pancreatic biopsies by minimal tail resection in live adult patients at the onset of type 1 diabetes: Experiences from the DiViD study
-
Krogvold L, Edwin B, Buanes T, et al. Pancreatic biopsies by minimal tail resection in live adult patients at the onset of type 1 diabetes: experiences from the DiViD study. Diabetologia 2014; 57:841-843.
-
(2014)
Diabetologia
, vol.57
, pp. 841-843
-
-
Krogvold, L.1
Edwin, B.2
Buanes, T.3
-
10
-
-
84908052466
-
Antibody-validated proteins in inflamed islets of fulminant type 1 diabetes profiled by laser capture microdissection followed by mass spectrometry
-
Nishida Y, Aida K, Kihara M, Kobayashi T. Antibody-validated proteins in inflamed islets of fulminant type 1 diabetes profiled by laser capture microdissection followed by mass spectrometry. PLOS one 2014; 9:e107664.
-
(2014)
PLOS One
, vol.9
, pp. e107664
-
-
Nishida, Y.1
Aida, K.2
Kihara, M.3
Kobayashi, T.4
-
11
-
-
84898441161
-
Gene expression analysis of human islets in a subject at onset of type 1 diabetes
-
Hopfgarten J, Stenwall PA, Wilberg A, et al. Gene expression analysis of human islets in a subject at onset of type 1 diabetes. Acta Diabetol 2014; 51:199-204.
-
(2014)
Acta Diabetol
, vol.51
, pp. 199-204
-
-
Hopfgarten, J.1
Stenwall, P.A.2
Wilberg, A.3
-
12
-
-
84905018256
-
Hyaluronan and hyaluronanbinding proteins accumulate in both human type 1 diabetic islets and lymphoid tissues and associate with inflammatory cells in insulitis
-
Bogdani M, Johnson PY, Potter-Perigo RS, et al. Hyaluronan and hyaluronanbinding proteins accumulate in both human type 1 diabetic islets and lymphoid tissues and associate with inflammatory cells in insulitis. Diabetes 2014; 63:2727-2743.
-
(2014)
Diabetes
, vol.63
, pp. 2727-2743
-
-
Bogdani, M.1
Johnson, P.Y.2
Potter-Perigo, R.S.3
-
13
-
-
84891872943
-
Increased complement activation in human type 1 diabetes pancreata
-
Rowe P, Wasserfall C, Croker B, et al. Increased complement activation in human type 1 diabetes pancreata. Diabetes Care 2014; 36:3815-3817.
-
(2014)
Diabetes Care
, vol.36
, pp. 3815-3817
-
-
Rowe, P.1
Wasserfall, C.2
Croker, B.3
-
14
-
-
84873051300
-
The peri-islet basement membrane, a barrier to infiltrating leucocytes in type 1 diabetes in mouse and human
-
Korpos E, Kadri N, Kappelhoff R, et al. The peri-islet basement membrane, a barrier to infiltrating leucocytes in type 1 diabetes in mouse and human. Diabetes 2013; 62:531-542.
-
(2013)
Diabetes
, vol.62
, pp. 531-542
-
-
Korpos, E.1
Kadri, N.2
Kappelhoff, R.3
-
15
-
-
84882319996
-
Insulin-dependent diabetes induced by pancreatic beta cell expression of IL-15 and IL15-Ra
-
Chen J, Feigenbaum L, Aswashti P, et al. Insulin-dependent diabetes induced by pancreatic beta cell expression of IL-15 and IL15-Ra. Proc Natl Acad Sci USA 2013; 110:13534-13539.
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 13534-13539
-
-
Chen, J.1
Feigenbaum, L.2
Aswashti, P.3
-
16
-
-
84871607997
-
Expression of the enteroviral capsid protein VP1 in the islet cells of patients with type 1 diabetes is associated with induction of protein kinase R and downregulation of Mcl-1
-
Richardson SJ, Leete P, Bone AJ, et al. Expression of the enteroviral capsid protein VP1 in the islet cells of patients with type 1 diabetes is associated with induction of protein kinase R and downregulation of Mcl-1. Diabetologia 2013; 56:185-193.
-
(2013)
Diabetologia
, vol.56
, pp. 185-193
-
-
Richardson, S.J.1
Leete, P.2
Bone, A.J.3
-
17
-
-
84893693165
-
Evaluation of the fidelity of immunolabelling obtained with clone 5D8/1, a monoclonal antibody directed against the enteroviral capsid protein VP1, in human pancreas
-
Richardson SJ, Leete P, Dhayal S, et al. Evaluation of the fidelity of immunolabelling obtained with clone 5D8/1, a monoclonal antibody directed against the enteroviral capsid protein VP1, in human pancreas. Diabetologia 2014; 57:392-401.
-
(2014)
Diabetologia
, vol.57
, pp. 392-401
-
-
Richardson, S.J.1
Leete, P.2
Dhayal, S.3
-
18
-
-
84926648661
-
Potential viral pathogenic mechanism in human type 1 diabetes
-
Schneider DA, von Herrath MG. Potential viral pathogenic mechanism in human type 1 diabetes. Diabetologia 2014; 57:2009-2018.
-
(2014)
Diabetologia
, vol.57
, pp. 2009-2018
-
-
Schneider, D.A.1
Von Herrath, M.G.2
-
19
-
-
84856825977
-
Demonstration of islet-autoreactive CD8 T cells in insulitic lesions from recent onset and long-term type 1 diabetes patients
-
Coppieters KT, Dotta F, Amirian N, et al. Demonstration of islet-autoreactive CD8 T cells in insulitic lesions from recent onset and long-term type 1 diabetes patients. J Exp Med 2012; 209:51-60.
-
(2012)
J Exp Med
, vol.209
, pp. 51-60
-
-
Coppieters, K.T.1
Dotta, F.2
Amirian, N.3
-
20
-
-
84908635248
-
Increased immune cell infiltration of the exocrine pancreas: A possible contribution to the pathogenesis of type 1 diabetes
-
Rodriguez-Calvo T, Ekwall O, Amirian N, et al. Increased immune cell infiltration of the exocrine pancreas: a possible contribution to the pathogenesis of type 1 diabetes. Diabetes 2014; 63:3880-3890.
-
(2014)
Diabetes
, vol.63
, pp. 3880-3890
-
-
Rodriguez-Calvo, T.1
Ekwall, O.2
Amirian, N.3
-
21
-
-
84926376813
-
B-cell-specific CD8 T cell phenotype in type 1 diabetes reflects chronic autoantigen exposure
-
Epub ahead of print
-
Skowera A, Ladell K, McLaren JE, et al. b-cell-specific CD8 T cell phenotype in type 1 diabetes reflects chronic autoantigen exposure. Diabetes 2014. [Epub ahead of print]
-
(2014)
Diabetes
-
-
Skowera, A.1
Ladell, K.2
McLaren, J.E.3
-
22
-
-
84872018209
-
Recent lessons learned from prevention and recent-onset type 1 diabetes immunotherapy trials
-
Staeva TP, Chatenoud L, Insel R, Atkinson MA. Recent lessons learned from prevention and recent-onset type 1 diabetes immunotherapy trials. Diabetes 2013; 62:9-17.
-
(2013)
Diabetes
, vol.62
, pp. 9-17
-
-
Staeva, T.P.1
Chatenoud, L.2
Insel, R.3
Atkinson, M.A.4
-
24
-
-
84896077776
-
What is the role of autoimmunity in type 1 diabetes? A clinical perspective
-
Donath MY, Hess C, Palmer E. What is the role of autoimmunity in type 1 diabetes? A clinical perspective. Diabetologia 2013; 57:653-655.
-
(2013)
Diabetologia
, vol.57
, pp. 653-655
-
-
Donath, M.Y.1
Hess, C.2
Palmer, E.3
-
25
-
-
84892578610
-
Is it time to challenge the established theories surrounding type 1 diabetes?
-
Ludviggson J. Is it time to challenge the established theories surrounding type 1 diabetes? Acta Paediatr 2014; 103:120-123.
-
(2014)
Acta Paediatr
, vol.103
, pp. 120-123
-
-
Ludviggson, J.1
-
26
-
-
84875451200
-
Defining the transcriptional and cellular landscape of type 1 diabetes in the NOD mouse
-
Carrero JA, Calderon B, Towfic F, et al. Defining the transcriptional and cellular landscape of type 1 diabetes in the NOD mouse. PLoS One 2013; 8:e59701.
-
(2013)
PLoS One
, vol.8
, pp. e59701
-
-
Carrero, J.A.1
Calderon, B.2
Towfic, F.3
-
27
-
-
58149299735
-
Analysis of islet inflammation in human type 1 diabetes
-
Willcox A, Richardson SJ, Bone AJ, et al. Analysis of islet inflammation in human type 1 diabetes. Clin Exp Immunol 2008; 155:173-181.
-
(2008)
Clin Exp Immunol
, vol.155
, pp. 173-181
-
-
Willcox, A.1
Richardson, S.J.2
Bone, A.J.3
-
28
-
-
34548397755
-
Screening for insulitis in adult autoantibody-positive organ donors
-
Int Veld P, Lievens D, De Grijse J, et al. Screening for insulitis in adult autoantibody-positive organ donors. Diabetes 2007; 56:2400-2404.
-
(2007)
Diabetes
, vol.56
, pp. 2400-2404
-
-
Int Veld, P.1
Lievens, D.2
De Grijse, J.3
-
30
-
-
0027078251
-
Pancreatic beta cells in insulin-dependent diabetes
-
Pipeleers D, Ling Z. Pancreatic beta cells in insulin-dependent diabetes. Diab Metab Rev 1992; 8:209-227.
-
(1992)
Diab Metab Rev
, vol.8
, pp. 209-227
-
-
Pipeleers, D.1
Ling, Z.2
-
31
-
-
84919427535
-
New insight on human type 1 diabetes biology: NPOD and nPOD transplantation
-
Pugliese A, Vendrame F, Reijonen H, et al. New insight on human type 1 diabetes biology: nPOD and nPOD transplantation. Curr Diab Rep 2014; 14:530.
-
(2014)
Curr Diab Rep
, vol.14
, pp. 530
-
-
Pugliese, A.1
Vendrame, F.2
Reijonen, H.3
|