-
1
-
-
84978929772
-
-
ASM Press, Washington, DC
-
Walsh C, Wencewicz T (2016) Antibiotics: challenges, mechanisms, opportunities. ASM Press, Washington, DC
-
(2016)
Antibiotics: Challenges, Mechanisms, Opportunities
-
-
Walsh, C.1
Wencewicz, T.2
-
2
-
-
84955461306
-
Antibacterial drug discovery in the resistance era
-
Brown ED, Wright GD (2016) Antibacterial drug discovery in the resistance era. Nature 529:336–343. doi:10.1038/nature17042
-
(2016)
Nature
, vol.529
, pp. 336-343
-
-
Brown, E.D.1
Wright, G.D.2
-
3
-
-
85002341700
-
New antibiotics from nature’s chemical inventory
-
Wencewicz TA (2016) New antibiotics from nature’s chemical inventory. Bioorg Med Chem 24:6227–6252. doi:10.1016/j.bmc.2016.09.014
-
(2016)
Bioorg Med Chem
, vol.24
, pp. 6227-6252
-
-
Wencewicz, T.A.1
-
4
-
-
84951845275
-
Targeted treatment for bacterial infections: Prospects for pathogen-specific antibiotics coupled with rapid diagnostics
-
Maxson T, Mitchell DA (2016) Targeted treatment for bacterial infections: prospects for pathogen-specific antibiotics coupled with rapid diagnostics. Tetrahedron 72:3609–3624. doi:10.1016/j.tet.2015.09.069
-
(2016)
Tetrahedron
, vol.72
, pp. 3609-3624
-
-
Maxson, T.1
Mitchell, D.A.2
-
5
-
-
64649088018
-
Outer membrane permeability and antibiotic resistance
-
Delcour AH (2009) Outer membrane permeability and antibiotic resistance. Biochim Biophys Acta 1794:808–816. doi:10.1016/j.bbapap.2008.11.005
-
(2009)
Biochim Biophys Acta
, vol.1794
, pp. 808-816
-
-
Delcour, A.H.1
-
6
-
-
84963979272
-
Permeability barrier of Gram-negative cell envelopes and approaches to bypass it
-
Zgurskaya HI, Lopez CA, Gnanakaran S (2015) Permeability barrier of Gram-negative cell envelopes and approaches to bypass it. ACS Infect Dis 1:512–522. doi:10.1021/acsinfecdis. 5b00097
-
(2015)
ACS Infect Dis
, vol.1
, pp. 512-522
-
-
Zgurskaya, H.I.1
Lopez, C.A.2
Gnanakaran, S.3
-
8
-
-
84955307030
-
Tabtoxinine-β-lactam is a “stealth” β-lactam antibiotic that evades β-lactamase-mediated antibiotic resistance
-
Hart KM, Reck M, Bowman GR, Wencewicz TA (2016) Tabtoxinine-β-lactam is a “stealth” β-lactam antibiotic that evades β-lactamase-mediated antibiotic resistance. Med Chem Commun 7:118–127. doi:10.1039/C5MD00325C
-
(2016)
Med Chem Commun
, vol.7
, pp. 118-127
-
-
Hart, K.M.1
Reck, M.2
Bowman, G.R.3
Wencewicz, T.A.4
-
9
-
-
79952578695
-
Maximizing the therapeutic window of an antimicrobial drug by imparting mitochondrial sequestration in human cells
-
Pereira MP, Kelley SO (2011) Maximizing the therapeutic window of an antimicrobial drug by imparting mitochondrial sequestration in human cells. J Am Chem Soc 133:3260–3263. doi:10.1021/ja110246u
-
(2011)
J am Chem Soc
, vol.133
, pp. 3260-3263
-
-
Pereira, M.P.1
Kelley, S.O.2
-
10
-
-
0033598377
-
Glycosylation of fluoroquinolones through direct and oxygenated polymethylene linkages as a sugar-mediated active transport system for antimicrobials
-
Jung ME, Yang EC, Vu BT, Kiankarimi M, Spyrou E, Kaunitz J (1999) Glycosylation of fluoroquinolones through direct and oxygenated polymethylene linkages as a sugar-mediated active transport system for antimicrobials. J Med Chem 42:3899–3909. doi:10.1021/jm990015b
-
(1999)
J Med Chem
, vol.42
, pp. 3899-3909
-
-
Jung, M.E.1
Yang, E.C.2
Vu, B.T.3
Kiankarimi, M.4
Spyrou, E.5
Kaunitz, J.6
-
11
-
-
84940556588
-
An efficient system for intracellular delivery of beta-lactam antibiotics to overcome bacterial resistance
-
Abed N, Said-Hassane F, Zouhiri F, Mougin J, Nicolas V, Desmaele D, Gref R, Couvreur P (2015) An efficient system for intracellular delivery of beta-lactam antibiotics to overcome bacterial resistance. Sci Rep 5:13500. doi:10.1038/srep13500
-
(2015)
Sci Rep
, vol.5
-
-
Abed, N.1
Said-Hassane, F.2
Zouhiri, F.3
Mougin, J.4
Nicolas, V.5
Desmaele, D.6
Gref, R.7
Couvreur, P.8
-
12
-
-
84919698126
-
Antibiotic-containing polymers for localized, sustained drug delivery
-
Stebbins ND, Ouimet MA, Uhrich KE (2014) Antibiotic-containing polymers for localized, sustained drug delivery. Adv Drug Deliv Rev 78:77–87. doi:10.1016/j.addr.2014.04.006
-
(2014)
Adv Drug Deliv Rev
, vol.78
, pp. 77-87
-
-
Stebbins, N.D.1
Ouimet, M.A.2
Uhrich, K.E.3
-
13
-
-
84919660351
-
Delivery of antibiotics with polymeric particles
-
Xiong M-H, Bao Y, Yang X-Z, Zhu Y-H, Wang J (2014) Delivery of antibiotics with polymeric particles. Adv Drug Deliv Rev 78:63–76. doi:10.1016/j.addr.2014.02.002
-
(2014)
Adv Drug Deliv Rev
, vol.78
, pp. 63-76
-
-
Xiong, M.-H.1
Bao, Y.2
Yang, X.-Z.3
Zhu, Y.-H.4
Wang, J.5
-
14
-
-
84947751820
-
Novel antibody–antibiotic conjugate eliminates intracellular S. Aureus
-
Lehar SM, Pillow T, Xu M, Staben L, Kajihara KK, Vandlen R, DePalatis L, Raab H, Hazenbos WL, Hiroshi Morisaki J, Kim J, Park S, Darwish M, Lee B-C, Hernandez H, Loyet KM, Lupardus P, Fong R, Yan D, Chalouni C, Luis E, Khalfin Y, Plise E, Cheong J, Lyssikatos JP, Strandh M, Koefoed K, Andersen PS, Flygare JA, Wah Tan M, Brown EJ, Mariathasan S (2015) Novel antibody–antibiotic conjugate eliminates intracellular S. aureus. Nature 527:323–328. doi:10.1038/nature16057
-
(2015)
Nature
, vol.527
, pp. 323-328
-
-
Lehar, S.M.1
Pillow, T.2
Xu, M.3
Staben, L.4
Kajihara, K.K.5
Vandlen, R.6
Depalatis, L.7
Raab, H.8
Hazenbos, W.L.9
Hiroshi Morisaki, J.10
Kim, J.11
Park, S.12
Darwish, M.13
Lee, B.-C.14
Hernandez, H.15
Loyet, K.M.16
Lupardus, P.17
Fong, R.18
Yan, D.19
Chalouni, C.20
Luis, E.21
Khalfin, Y.22
Plise, E.23
Cheong, J.24
Lyssikatos, J.P.25
Strandh, M.26
Koefoed, K.27
Andersen, P.S.28
Flygare, J.A.29
Wah Tan, M.30
Brown, E.J.31
Mariathasan, S.32
more..
-
15
-
-
0034044581
-
Studies and syntheses of siderophores, microbial iron chelators, and analogs as potential drug delivery agents
-
Roosenberg II JM, Lin YM, Lu Y, Miller MJ (2000) Studies and syntheses of siderophores, microbial iron chelators, and analogs as potential drug delivery agents. Curr Med Chem 7:159–197. doi:10.2174/0929867003375353
-
(2000)
Curr Med Chem
, vol.7
, pp. 159-197
-
-
Roosenberg, J.M.1
Lin, Y.M.2
Lu, Y.3
Miller, M.J.4
-
16
-
-
85010424985
-
Wall teichoic acids mediate increased virulence in Staphylococcus aureus
-
Wanner S, Schade J, Keinh€orster D, Weller N, George SE, Kull L, Bauer J, Grau T, Winstel V, Stoy H, Kretschmer D, Kolata J, Wolz C, Br€oker BM, Weidenmaier C (2017) Wall teichoic acids mediate increased virulence in Staphylococcus aureus. Nat Microbiol 2:16257. doi:10.1038/nmicrobiol.2016.257
-
(2017)
Nat Microbiol
, vol.2
, pp. 16257
-
-
Wanner, S.1
Schade, J.2
Keinh€Orster, D.3
Weller, N.4
George, S.E.5
Kull, L.6
Bauer, J.7
Grau, T.8
Winstel, V.9
Stoy, H.10
Kretschmer, D.11
Kolata, J.12
Wolz, C.13
Br€Oker, B.M.14
Weidenmaier, C.15
-
17
-
-
75949092121
-
Anti-virulence strategies to combat bacteria-mediated disease
-
Rasko DA, Sperandio V (2010) Anti-virulence strategies to combat bacteria-mediated disease. Nat Rev Drug Discov 9:117–128. doi:10.1038/nrd3013
-
(2010)
Nat Rev Drug Discov
, vol.9
, pp. 117-128
-
-
Rasko, D.A.1
Sperandio, V.2
-
18
-
-
59449092463
-
Sideromycins: Tools and antibiotics
-
Braun V, Pramanik A, Gwinner T, Koberle M, Bohn E (2009) Sideromycins: tools and antibiotics. Biometals 22:3–13. doi:10.1007/s10534-008-9199-7
-
(2009)
Biometals
, vol.22
, pp. 3-13
-
-
Braun, V.1
Pramanik, A.2
Gwinner, T.3
Koberle, M.4
Bohn, E.5
-
19
-
-
85000838210
-
Transition metals and virulence in bacteria
-
Palmer LD, Skaar EP (2016) Transition metals and virulence in bacteria. Annu Rev Genet 50:67–91. doi:10.1146/annurev-genet-120215-035146
-
(2016)
Annu Rev Genet
, vol.50
, pp. 67-91
-
-
Palmer, L.D.1
Skaar, E.P.2
-
20
-
-
77958143617
-
The battle for iron between bacterial pathogens and their vertebrate hosts
-
Skaar EP (2010) The battle for iron between bacterial pathogens and their vertebrate hosts. PLoS Pathog 6:e1000949. doi:10.1371/journal.ppat.1000949
-
(2010)
Plos Pathog
, vol.6
-
-
Skaar, E.P.1
-
21
-
-
84963769435
-
Bacterial ferrous iron transport: The Feo system
-
Lau CK, Krewulak KD, Vogel HJ (2016) Bacterial ferrous iron transport: the Feo system. FEMS Microbiol Rev 40:273–298. doi:10.1093/femsre/fuv049
-
(2016)
FEMS Microbiol Rev
, vol.40
, pp. 273-298
-
-
Lau, C.K.1
Krewulak, K.D.2
Vogel, H.J.3
-
22
-
-
84889573712
-
Bacterial receptors for host transferrin and lactoferrin: Molecular mechanisms and role in host-microbe interactions
-
Morgenthau A, Pogoutse A, Adamiak P, Moraes TF, Schryvers AB (2013) Bacterial receptors for host transferrin and lactoferrin: molecular mechanisms and role in host-microbe interactions. Future Microbiol 8:1575–1585. doi:10.2217/fmb.13.125
-
(2013)
Future Microbiol
, vol.8
, pp. 1575-1585
-
-
Morgenthau, A.1
Pogoutse, A.2
Adamiak, P.3
Moraes, T.F.4
Schryvers, A.B.5
-
24
-
-
77951981537
-
Chemistry and biology of siderophores
-
Hider RC, Kong X (2010) Chemistry and biology of siderophores. Nat Prod Rep 27:637–657. doi:10.1039/b906679a
-
(2010)
Nat Prod Rep
, vol.27
, pp. 637-657
-
-
Hider, R.C.1
Kong, X.2
-
25
-
-
84931074436
-
Diverging roles of bacterial siderophores during infection
-
Holden VI, Bachman MA (2015) Diverging roles of bacterial siderophores during infection. Metallomics 7:986–995. doi:10.1039/c4mt00333k
-
(2015)
Metallomics
, vol.7
, pp. 986-995
-
-
Holden, V.I.1
Bachman, M.A.2
-
26
-
-
67651244131
-
Siderocalins: Siderophore-binding proteins of the innate immune system
-
Clifton MC, Corrent C, Strong RK (2009) Siderocalins: siderophore-binding proteins of the innate immune system. Biometals 22:557–564. doi:10.1007/s10534-009-9207-6
-
(2009)
Biometals
, vol.22
, pp. 557-564
-
-
Clifton, M.C.1
Corrent, C.2
Strong, R.K.3
-
27
-
-
84940527191
-
Human urinary composition controls siderocalin’s antibacterial activity
-
Shields-Cutler RR, Crowley JR, Hung CS, Stapleton AE, Aldrich CC, Marschall J, Henderson JP (2015) Human urinary composition controls siderocalin’s antibacterial activity. J Biol Chem 290:15949–15960. doi:10.1074/jbc.M115.645812
-
(2015)
J Biol Chem
, vol.290
, pp. 15949-15960
-
-
Shields-Cutler, R.R.1
Crowley, J.R.2
Hung, C.S.3
Stapleton, A.E.4
Aldrich, C.C.5
Marschall, J.6
Henderson, J.P.7
-
28
-
-
85002835024
-
Human metabolome-derived cofactors are required for the antibacterial activity of siderocalin in urine
-
Shields-Cutler RR, Crowley JR, Miller CD, Stapleton AE, Cui W, Henderson JP (2016) Human metabolome-derived cofactors are required for the antibacterial activity of siderocalin in urine. J Biol Chem 291:25901–25910. doi:10.1074/jbc.M116.759183
-
(2016)
J Biol Chem
, vol.291
, pp. 25901-25910
-
-
Shields-Cutler, R.R.1
Crowley, J.R.2
Miller, C.D.3
Stapleton, A.E.4
Cui, W.5
Henderson, J.P.6
-
29
-
-
33845504862
-
Anthrax pathogen evades the mammalian immune system through stealth siderophore production
-
Abergel RJ, Wilson MK, Arceneaux JE, Hoette TM, Strong RK, Byers BR, Raymond KN (2006) Anthrax pathogen evades the mammalian immune system through stealth siderophore production. Proc Natl Acad Sci U S A 103:18499–18503. doi:10.1073/pnas.0607055103
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 18499-18503
-
-
Abergel, R.J.1
Wilson, M.K.2
Arceneaux, J.E.3
Hoette, T.M.4
Strong, R.K.5
Byers, B.R.6
Raymond, K.N.7
-
30
-
-
33748051446
-
Microbial evasion of the immune system: Structural modifications of enterobactin impair siderocalin recognition
-
Abergel RJ, Moore EG, Strong RK, Raymond KN (2006) Microbial evasion of the immune system: structural modifications of enterobactin impair siderocalin recognition. J Am Chem Soc 128:10998–10999. doi:10.1021/ja062476+
-
(2006)
J am Chem Soc
, vol.128
, pp. 10998-10999
-
-
Abergel, R.J.1
Moore, E.G.2
Strong, R.K.3
Raymond, K.N.4
-
31
-
-
33646593180
-
How pathogenic bacteria evade mammalian sabotage in the battle for iron
-
Fischbach MA, Lin H, Liu DR, Walsh CT (2006) How pathogenic bacteria evade mammalian sabotage in the battle for iron. Nat Chem Biol 2:132–138. doi:10.1038/nchembio771
-
(2006)
Nat Chem Biol
, vol.2
, pp. 132-138
-
-
Fischbach, M.A.1
Lin, H.2
Liu, D.R.3
Walsh, C.T.4
-
32
-
-
84903457328
-
Aspergillomarasmine A overcomes metallo-β-lactamase antibiotic resistance
-
King AM, Reid-Yu SA, Wang W, King DT, De Pascale G, Strynadka NC, Walsh TR, Coombes BK, Wright GD (2014) Aspergillomarasmine A overcomes metallo-β-lactamase antibiotic resistance. Nature 510:503–506. doi:10.1038/nature13445
-
(2014)
Nature
, vol.510
, pp. 503-506
-
-
King, A.M.1
Reid-Yu, S.A.2
Wang, W.3
King, D.T.4
de Pascale, G.5
Strynadka, N.C.6
Walsh, T.R.7
Coombes, B.K.8
Wright, G.D.9
-
33
-
-
85014734991
-
Role for dithiolopyrrolones in disrupting bacterial metal homeostasis
-
Chan AN, Shiver AL, Wever WJ, Razvi SZA, Traxler MF, Li B (2017) Role for dithiolopyrrolones in disrupting bacterial metal homeostasis. Proc Natl Acad Sci U S A 114:2717–2722. doi:10.1073/pnas.1612810114
-
(2017)
Proc Natl Acad Sci U S A
, vol.114
, pp. 2717-2722
-
-
Chan, A.N.1
Shiver, A.L.2
Wever, W.J.3
Razvi, S.Z.A.4
Traxler, M.F.5
Li, B.6
-
34
-
-
84930225222
-
Breaking a pathogen’s iron will: Inhibiting siderophore production as an antimicrobial strategy
-
Lamb AL (2015) Breaking a pathogen’s iron will: inhibiting siderophore production as an antimicrobial strategy. Biochim Biophys Acta 1854:1054–1070. doi:10.1016/j.bbapap.2015. 05.001
-
(2015)
Biochim Biophys Acta
, vol.1854
, pp. 1054-1070
-
-
Lamb, A.L.1
-
35
-
-
84875696130
-
Non-nucleoside inhibitors of BasE, an adenylating enzyme in the siderophore biosynthetic pathway of the opportunistic pathogen Acinetobacter baumannii
-
Neres J, Engelhart CA, Drake EJ, Wilson DJ, Fu P, Boshoff HI, Barry 3rd CE, Gulick AM, Aldrich CC (2013) Non-nucleoside inhibitors of BasE, an adenylating enzyme in the siderophore biosynthetic pathway of the opportunistic pathogen Acinetobacter baumannii. J Med Chem 56:2385–2405. doi:10.1021/jm301709s
-
(2013)
J Med Chem
, vol.56
, pp. 2385-2405
-
-
Neres, J.1
Engelhart, C.A.2
Drake, E.J.3
Wilson, D.J.4
Fu, P.5
Boshoff, H.I.6
Barry, C.E.7
Gulick, A.M.8
Aldrich, C.C.9
-
36
-
-
84904541042
-
Identification of inhibitors of PvdQ, an enzyme involved in the synthesis of the siderophore pyoverdine
-
Wurst JM, Drake EJ, Theriault JR, Jewett IT, VerPlank L, Perez JR, Dandapani S, Palmer M, Moskowitz SM, Schreiber SL, Munoz B, Gulick AM (2014) Identification of inhibitors of PvdQ, an enzyme involved in the synthesis of the siderophore pyoverdine. ACS Chem Biol 9:1536–1544. doi:10.1021/cb5001586
-
(2014)
ACS Chem Biol
, vol.9
, pp. 1536-1544
-
-
Wurst, J.M.1
Drake, E.J.2
Theriault, J.R.3
Jewett, I.T.4
Verplank, L.5
Perez, J.R.6
Dandapani, S.7
Palmer, M.8
Moskowitz, S.M.9
Schreiber, S.L.10
Munoz, B.11
Gulick, A.M.12
-
37
-
-
84996866505
-
Inhibition of the flavin-dependent monooxygenase siderophore A (SidA) blocks siderophore biosynthesis and aspergillus fumigatus growth
-
Martín del Campo JS, Vogelaar N, Tolani K, Kizjakina K, Harich K, Sobrado P (2016) Inhibition of the flavin-dependent monooxygenase siderophore A (SidA) blocks siderophore biosynthesis and aspergillus fumigatus growth. ACS Chem Biol 11:3035–3042. doi:10.1021/acschembio.6b00666
-
(2016)
ACS Chem Biol
, vol.11
, pp. 3035-3042
-
-
Martín Del Campo, J.S.1
Vogelaar, N.2
Tolani, K.3
Kizjakina, K.4
Harich, K.5
Sobrado, P.6
-
38
-
-
77954134675
-
Inhibition studies of Mycobacterium tuberculosis salicylate synthase (MbtI)
-
Manos-Turvey A, Bulloch EM, Rutledge PJ, Baker EN, Lott JS, Payne RJ (2010) Inhibition studies of Mycobacterium tuberculosis salicylate synthase (MbtI). ChemMedChem 5:1067–1079. doi:10.1002/cmdc.201000137
-
(2010)
Chemmedchem
, vol.5
, pp. 1067-1079
-
-
Manos-Turvey, A.1
Bulloch, E.M.2
Rutledge, P.J.3
Baker, E.N.4
Lott, J.S.5
Payne, R.J.6
-
39
-
-
0037073693
-
The antibiotic activity of N-pentylpantothenamide results from its conversion to ethyldethia-coenzyme A, a coenzyme A antimetabolite
-
Strauss E, Begley TP (2002) The antibiotic activity of N-pentylpantothenamide results from its conversion to ethyldethia-coenzyme A, a coenzyme A antimetabolite. J Biol Chem 277:48205–48209. doi:10.1074/jbc.M204560200
-
(2002)
J Biol Chem
, vol.277
, pp. 48205-48209
-
-
Strauss, E.1
Begley, T.P.2
-
40
-
-
30344458817
-
Structure–activity relationships and enzyme inhibition of pantothenamide-type pantothenate kinase inhibitors
-
Virga KG, Zhang Y-M, Leonardi R, Ivey RA, Hevener K, Park H-W, Jackowski S, Rock CO, Lee RE (2006) Structure–activity relationships and enzyme inhibition of pantothenamide-type pantothenate kinase inhibitors. Bioorg Med Chem 14:1007–1020. doi:10.1016/j.bmc. 2005.09.021
-
(2006)
Bioorg Med Chem
, vol.14
, pp. 1007-1020
-
-
Virga, K.G.1
Zhang, Y.-M.2
Leonardi, R.3
Ivey, R.A.4
Hevener, K.5
Park, H.-W.6
Jackowski, S.7
Rock, C.O.8
Lee, R.E.9
-
41
-
-
84861631111
-
The antibiotic CJ-15,801 is an antimetabolite that hijacks and then inhibits CoA biosynthesis
-
van der Westhuyzen R, Hammons Justin C, Meier Jordan L, Dahesh S, Moolman Wessel JA, Pelly Stephen C, Nizet V, Burkart Michael D, Strauss E (2012) The antibiotic CJ-15,801 is an antimetabolite that hijacks and then inhibits CoA biosynthesis. Chem Biol 19:559–571. doi:10.1016/j.chembiol.2012.03.013
-
(2012)
Chem Biol
, vol.19
, pp. 559-571
-
-
van der Westhuyzen, R.1
Hammons Justin, C.2
Meier Jordan, L.3
Dahesh, S.4
Moolman Wessel, J.A.5
Pelly Stephen, C.6
Nizet, V.7
Burkart Michael, D.8
Strauss, E.9
-
42
-
-
0348141912
-
Role of siderophore biosynthesis in virulence of Staphylococcus aureus: Identification and characterization of genes involved in production of a siderophore
-
Dale SE, Doherty-Kirby A, Lajoie G, Heinrichs DE (2004) Role of siderophore biosynthesis in virulence of Staphylococcus aureus: identification and characterization of genes involved in production of a siderophore. Infect Immun 72:29–37. doi:10.1128/IAI.72.1.29-37.2004
-
(2004)
Infect Immun
, vol.72
, pp. 29-37
-
-
Dale, S.E.1
Doherty-Kirby, A.2
Lajoie, G.3
Heinrichs, D.E.4
-
43
-
-
84893499425
-
Baulamycins A and B, broad-spectrum antibiotics identified as inhibitors of siderophore biosynthesis in Staphylococcus aureus and Bacillus anthracis
-
Tripathi A, Schofield MM, Chlipala GE, Schultz PJ, Yim I, Newmister SA, Nusca TD, Scaglione JB, Hanna PC, Tamayo-Castillo G, Sherman DH (2014) Baulamycins A and B, broad-spectrum antibiotics identified as inhibitors of siderophore biosynthesis in Staphylococcus aureus and Bacillus anthracis. J Am Chem Soc 136:1579–1586. doi:10.1021/ja4115924
-
(2014)
J am Chem Soc
, vol.136
, pp. 1579-1586
-
-
Tripathi, A.1
Schofield, M.M.2
Chlipala, G.E.3
Schultz, P.J.4
Yim, I.5
Newmister, S.A.6
Nusca, T.D.7
Scaglione, J.B.8
Hanna, P.C.9
Tamayo-Castillo, G.10
Sherman, D.H.11
-
45
-
-
0016591187
-
The effect of p-aminosalicyclic acid on iron transport and assimilation in mycobacteria
-
Brown KA, Ratledge C (1975) The effect of p-aminosalicyclic acid on iron transport and assimilation in mycobacteria. Biochim Biophys Acta 385:207–220
-
(1975)
Biochim Biophys Acta
, vol.385
, pp. 207-220
-
-
Brown, K.A.1
Ratledge, C.2
-
46
-
-
0345492332
-
Synergy and contingency as driving forces for the evolution of multiple secondary metabolite production by Streptomyces species
-
Challis GL, Hopwood DA (2003) Synergy and contingency as driving forces for the evolution of multiple secondary metabolite production by Streptomyces species. Proc Natl Acad Sci U S A 100:14555–14561. doi:10.1073/pnas.1934677100
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 14555-14561
-
-
Challis, G.L.1
Hopwood, D.A.2
-
47
-
-
0032569011
-
Total syntheses of mycobactin analogues as potent antimycobacterial agents using a minimal protecting group strategy
-
Xu Y, Miller MJ (1998) Total syntheses of mycobactin analogues as potent antimycobacterial agents using a minimal protecting group strategy. J Org Chem 63:4314–4322. doi:10.1021/jo980063o
-
(1998)
J Org Chem
, vol.63
, pp. 4314-4322
-
-
Xu, Y.1
Miller, M.J.2
-
48
-
-
84865694055
-
Syntheses of mycobactin analogs as potent and selective inhibitors of Mycobacterium tuberculosis
-
Juarez-Hernandez RE, Franzblau SG, Miller MJ (2012) Syntheses of mycobactin analogs as potent and selective inhibitors of Mycobacterium tuberculosis. Org Biomol Chem 10:7584–7593. doi:10.1039/c2ob26077h
-
(2012)
Org Biomol Chem
, vol.10
, pp. 7584-7593
-
-
Juarez-Hernandez, R.E.1
Franzblau, S.G.2
Miller, M.J.3
-
49
-
-
84893468680
-
Self-poisoning of Mycobacterium tuberculosis by interrupting siderophore recycling
-
Jones CM, Wells RM, Madduri AV, Renfrow MB, Ratledge C, Moody DB, Niederweis M (2014) Self-poisoning of Mycobacterium tuberculosis by interrupting siderophore recycling. Proc Natl Acad Sci U S A 111:1945–1950. doi:10.1073/pnas.1311402111
-
(2014)
Proc Natl Acad Sci U S A
, vol.111
, pp. 1945-1950
-
-
Jones, C.M.1
Wells, R.M.2
Madduri, A.V.3
Renfrow, M.B.4
Ratledge, C.5
Moody, D.B.6
Niederweis, M.7
-
50
-
-
84899769431
-
Inhibitors of TonB function identified by a high-throughput screen for inhibitors of iron acquisition in uropathogenic Escherichia coli CFT073
-
Yep A, McQuade T, Kirchhoff P, Larsen M, Mobley HLT (2014) Inhibitors of TonB function identified by a high-throughput screen for inhibitors of iron acquisition in uropathogenic Escherichia coli CFT073. MBio 5:e01089–e01013. doi:10.1128/mBio.01089-13
-
(2014)
Mbio
, vol.5
, pp. 89
-
-
Yep, A.1
McQuade, T.2
Kirchhoff, P.3
Larsen, M.4
Mobley, H.L.T.5
-
51
-
-
84959179863
-
High-throughput screening assay for inhibitors of TonB-dependent iron transport
-
Hanson M, Jordan LD, Shipelskiy Y, Newton SM, Klebba PE (2016) High-throughput screening assay for inhibitors of TonB-dependent iron transport. J Biomol Screen 21:316–322. doi:10.1177/1087057115613788
-
(2016)
J Biomol Screen
, vol.21
, pp. 316-322
-
-
Hanson, M.1
Jordan, L.D.2
Shipelskiy, Y.3
Newton, S.M.4
Klebba, P.E.5
-
52
-
-
55949122270
-
The potential of desferrioxamine-gallium as an anti-Pseudomonas therapeutic agent
-
Banin E, Lozinski A, Brady KM, Berenshtein E, Butterfield PW, Moshe M, Chevion M, Greenberg EP, Banin E (2008) The potential of desferrioxamine-gallium as an anti-Pseudomonas therapeutic agent. Proc Natl Acad Sci U S A 105:16761–16766. doi:10.1073/pnas. 0808608105
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 16761-16766
-
-
Banin, E.1
Lozinski, A.2
Brady, K.M.3
Berenshtein, E.4
Butterfield, P.W.5
Moshe, M.6
Chevion, M.7
Greenberg, E.P.8
Banin, E.9
-
53
-
-
84899503151
-
Promises and failures of gallium as an antibacterial agent
-
Minandri F, Bonchi C, Frangipani E, Imperi F, Visca P (2014) Promises and failures of gallium as an antibacterial agent. Future Microbiol 9:379–397. doi:10.2217/fmb.14.3
-
(2014)
Future Microbiol
, vol.9
, pp. 379-397
-
-
Minandri, F.1
Bonchi, C.2
Frangipani, E.3
Imperi, F.4
Visca, P.5
-
54
-
-
34548082362
-
Inhibition of the bacterial heme oxygenases from Pseudomonas aeruginosa and Neisseria meningitidis: Novel antimicrobial targets
-
Furci LM, Lopes P, Eakanunkul S, Zhong S, MacKerell AD, Wilks A (2007) Inhibition of the bacterial heme oxygenases from Pseudomonas aeruginosa and Neisseria meningitidis: novel antimicrobial targets. J Med Chem 50:3804–3813. doi:10.1021/jm0700969
-
(2007)
J Med Chem
, vol.50
, pp. 3804-3813
-
-
Furci, L.M.1
Lopes, P.2
Eakanunkul, S.3
Zhong, S.4
Mackerell, A.D.5
Wilks, A.6
-
56
-
-
67549116897
-
Vibriobactin antibodies: A vaccine strategy
-
Bergeron RJ, Bharti N, Singh S, McManis JS, Wiegand J, Green LG (2009) Vibriobactin antibodies: a vaccine strategy. J Med Chem 52:3801–3813. doi:10.1021/jm900119q
-
(2009)
J Med Chem
, vol.52
, pp. 3801-3813
-
-
Bergeron, R.J.1
Bharti, N.2
Singh, S.3
McManis, J.S.4
Wiegand, J.5
Green, L.G.6
-
57
-
-
84996528987
-
Siderophore vaccine conjugates protect against uropathogenic Escherichia coli urinary tract infection
-
Mike LA, Smith SN, Sumner CA, Eaton KA, Mobley HL (2016) Siderophore vaccine conjugates protect against uropathogenic Escherichia coli urinary tract infection. Proc Natl Acad Sci U S A 113:13468–13473. doi:10.1073/pnas.1606324113
-
(2016)
Proc Natl Acad Sci U S A
, vol.113
, pp. 13468-13473
-
-
Mike, L.A.1
Smith, S.N.2
Sumner, C.A.3
Eaton, K.A.4
Mobley, H.L.5
-
58
-
-
84996553457
-
Siderophore-based immunization strategy to inhibit growth of enteric pathogens
-
Sassone-Corsi M, Chairatana P, Zheng T, Perez-Lopez A, Edwards RA, George MD, Nolan EM, Raffatellu M (2016) Siderophore-based immunization strategy to inhibit growth of enteric pathogens. Proc Natl Acad Sci U S A 113:13462–13467. doi:10.1073/pnas. 1606290113
-
(2016)
Proc Natl Acad Sci U S A
, vol.113
, pp. 13462-13467
-
-
Sassone-Corsi, M.1
Chairatana, P.2
Zheng, T.3
Perez-Lopez, A.4
Edwards, R.A.5
George, M.D.6
Nolan, E.M.7
Raffatellu, M.8
-
59
-
-
0023227280
-
Passive immunization with antibodies against iron-regulated outer membrane proteins protects turkeys from Escherichia coli septicemia
-
Bolin CA, Jensen AE (1987) Passive immunization with antibodies against iron-regulated outer membrane proteins protects turkeys from Escherichia coli septicemia. Infect Immun 55:1239–1242
-
(1987)
Infect Immun
, vol.55
, pp. 1239-1242
-
-
Bolin, C.A.1
Jensen, A.E.2
-
60
-
-
0037159106
-
A laboratory study of an inactivated bivalent iron restricted Salmonella enterica serovars Enteritidis and Typhimurium dual vaccine against Typhimurium challenge in chickens
-
Clifton-Hadley FA, Breslin M, Venables LM, Sprigings KA, Cooles SW, Houghton S, Woodward MJ (2002) A laboratory study of an inactivated bivalent iron restricted Salmonella enterica serovars Enteritidis and Typhimurium dual vaccine against Typhimurium challenge in chickens. Vet Microbiol 89:167–179. doi:10.1016/S0378-1135(02)00169-4
-
(2002)
Vet Microbiol
, vol.89
, pp. 167-179
-
-
Clifton-Hadley, F.A.1
Breslin, M.2
Venables, L.M.3
Sprigings, K.A.4
Cooles, S.W.5
Houghton, S.6
Woodward, M.J.7
-
61
-
-
84884264246
-
Immunization with the yersiniabactin receptor, FyuA, protects against pyelonephritis in a murine model of urinary tract infection
-
Brumbaugh AR, Smith SN, Mobley HL (2013) Immunization with the yersiniabactin receptor, FyuA, protects against pyelonephritis in a murine model of urinary tract infection. Infect Immun 81:3309–3316. doi:10.1128/iai.00470-13
-
(2013)
Infect Immun
, vol.81
, pp. 3309-3316
-
-
Brumbaugh, A.R.1
Smith, S.N.2
Mobley, H.L.3
-
62
-
-
84872476902
-
Structural and functional characterization of the Staphylococcus aureus virulence factor and vaccine candidate FhuD2
-
Mariotti P, Malito E, Biancucci M, Lo Surdo P, Mishra RP, Nardi-Dei V, Savino S, Nissum M, Spraggon G, Grandi G, Bagnoli F, Bottomley MJ (2013) Structural and functional characterization of the Staphylococcus aureus virulence factor and vaccine candidate FhuD2. Biochem J 449:683–693. doi:10.1042/bj20121426
-
(2013)
Biochem J
, vol.449
, pp. 683-693
-
-
Mariotti, P.1
Malito, E.2
Biancucci, M.3
Lo Surdo, P.4
Mishra, R.P.5
Nardi-Dei, V.6
Savino, S.7
Nissum, M.8
Spraggon, G.9
Grandi, G.10
Bagnoli, F.11
Bottomley, M.J.12
-
63
-
-
85006043730
-
Siderophore-based microbial adaptations to iron scarcity across the eastern Pacific Ocean
-
doi:10. 1073/pnas.1608594113
-
Boiteau RM, Mende DR, Hawco NJ, McIlvin MR, Fitzsimmons JN, Saito MA, Sedwick PN, DeLong EF, Repeta DJ (2016) Siderophore-based microbial adaptations to iron scarcity across the eastern Pacific Ocean. Proc Natl Acad Sci U S A 113:14237–14242. doi:10. 1073/pnas.1608594113
-
(2016)
Proc Natl Acad Sci U S A
, vol.113
, pp. 14237-14242
-
-
Boiteau, R.M.1
Mende, D.R.2
Hawco, N.J.3
McIlvin, M.R.4
Fitzsimmons, J.N.5
Saito, M.A.6
Sedwick, P.N.7
Delong, E.F.8
Repeta, D.J.9
-
64
-
-
0036280341
-
Genetics and assembly line enzymology of siderophore biosynthesis in bacteria
-
Crosa JH, Walsh CT (2002) Genetics and assembly line enzymology of siderophore biosynthesis in bacteria. Microbiol Mol Biol Rev 66:223–249. doi:10.1128/MMBR.66.2.223-249.2002
-
(2002)
Microbiol Mol Biol Rev
, vol.66
, pp. 223-249
-
-
Crosa, J.H.1
Walsh, C.T.2
-
65
-
-
38649110468
-
Terephthalamide-containing ligands: Fast removal of iron from transferrin
-
Abergel RJ, Raymond KN (2008) Terephthalamide-containing ligands: fast removal of iron from transferrin. J Biol Inorg Chem 13:229–240. doi:10.1007/s00775-007-0314-y
-
(2008)
J Biol Inorg Chem
, vol.13
, pp. 229-240
-
-
Abergel, R.J.1
Raymond, K.N.2
-
66
-
-
84941686963
-
Coordination chemistry of microbial iron transport
-
Raymond KN, Allred BE, Sia AK (2015) Coordination chemistry of microbial iron transport. Acc Chem Res 48:2496–2505. doi:10.1021/acs.accounts.5b00301
-
(2015)
Acc Chem Res
, vol.48
, pp. 2496-2505
-
-
Raymond, K.N.1
Allred, B.E.2
Sia, A.K.3
-
67
-
-
84875454942
-
Trihydroxamate siderophore-fluoroquinolone conjugates are selective sideromycin antibiotics that target Staphylococcus aureus
-
Wencewicz TA, Long TE, M€ollmann U, Miller MJ (2013) Trihydroxamate siderophore-fluoroquinolone conjugates are selective sideromycin antibiotics that target Staphylococcus aureus. Bioconjug Chem 24:473–486. doi:10.1021/bc300610f
-
(2013)
Bioconjug Chem
, vol.24
, pp. 473-486
-
-
Wencewicz, T.A.1
Long, T.E.2
M€Ollmann, U.3
Miller, M.J.4
-
68
-
-
0037317173
-
Acquisition of siderophores in Gram-negative bacteria
-
Faraldo-Gomez JD, Sansom MS (2003) Acquisition of siderophores in Gram-negative bacteria. Nat Rev Mol Cell Biol 4:105–116. doi:10.1038/nrm1015
-
(2003)
Nat Rev Mol Cell Biol
, vol.4
, pp. 105-116
-
-
Faraldo-Gomez, J.D.1
Sansom, M.S.2
-
69
-
-
84896719872
-
Transcriptional regulation by ferric uptake regulator (Fur) in pathogenic bacteria
-
Troxell B, Hassan HM (2013) Transcriptional regulation by ferric uptake regulator (Fur) in pathogenic bacteria. Front Cell Infect Microbiol 3:59. doi:10.3389/fcimb.2013.00059
-
(2013)
Front Cell Infect Microbiol
, vol.3
-
-
Troxell, B.1
Hassan, H.M.2
-
70
-
-
78649685479
-
An efflux pump is involved in secretion of newly synthesized siderophore by Pseudomonas aeruginosa
-
Hannauer M, Yeterian E, Martin LW, Lamont IL, Schalk IJ (2010) An efflux pump is involved in secretion of newly synthesized siderophore by Pseudomonas aeruginosa. FEBS Lett 584:4751–4755. doi:10.1016/j.febslet.2010.10.051
-
(2010)
FEBS Lett
, vol.584
, pp. 4751-4755
-
-
Hannauer, M.1
Yeterian, E.2
Martin, L.W.3
Lamont, I.L.4
Schalk, I.J.5
-
71
-
-
77749270483
-
The ferrichrome uptake pathway in Pseudomonas aeruginosa involves an iron release mechanism with acylation of the siderophore and recycling of the modified desferrichrome
-
Hannauer M, Barda Y, Mislin GLA, Shanzer A, Schalk IJ (2010) The ferrichrome uptake pathway in Pseudomonas aeruginosa involves an iron release mechanism with acylation of the siderophore and recycling of the modified desferrichrome. J Bacteriol 192:1212–1220. doi:10.1128/jb.01539-09
-
(2010)
J Bacteriol
, vol.192
, pp. 1212-1220
-
-
Hannauer, M.1
Barda, Y.2
Mislin, G.L.A.3
Shanzer, A.4
Schalk, I.J.5
-
72
-
-
0032545324
-
Siderophore-mediated iron transport: Crystal structure of FhuA with bound lipopolysaccharide
-
Ferguson AD, Hofmann E, Coulton JW, Diederichs K, Welte W (1998) Siderophore-mediated iron transport: crystal structure of FhuA with bound lipopolysaccharide. Science 282:2215–2220
-
(1998)
Science
, vol.282
, pp. 2215-2220
-
-
Ferguson, A.D.1
Hofmann, E.2
Coulton, J.W.3
Diederichs, K.4
Welte, W.5
-
73
-
-
84990216639
-
Structural insight into the role of the Ton complex in energy transduction
-
Celia H, Noinaj N, Zakharov SD, Bordignon E, Botos I, Santamaria M, Barnard TJ, Cramer WA, Lloubes R, Buchanan SK (2016) Structural insight into the role of the Ton complex in energy transduction. Nature 538:60–65. doi:10.1038/nature19757
-
(2016)
Nature
, vol.538
, pp. 60-65
-
-
Celia, H.1
Noinaj, N.2
Zakharov, S.D.3
Bordignon, E.4
Botos, I.5
Santamaria, M.6
Barnard, T.J.7
Cramer, W.A.8
Lloubes, R.9
Buchanan, S.K.10
-
74
-
-
77956505672
-
TonB-dependent transporters: Regulation, structure, and function
-
Noinaj N, Guillier M, Barnard TJ, Buchanan SK (2010) TonB-dependent transporters: regulation, structure, and function. Annu Rev Microbiol 64:43–60. doi:10.1146/annurev. micro.112408.134247
-
(2010)
Annu Rev Microbiol
, vol.64
, pp. 43-60
-
-
Noinaj, N.1
Guillier, M.2
Barnard, T.J.3
Buchanan, S.K.4
-
75
-
-
84867670628
-
Structure of AMP-PNP-bound vitamin B12 transporter BtuCD-F
-
Korkhov VM, Mireku SA, Locher KP (2012) Structure of AMP-PNP-bound vitamin B12 transporter BtuCD-F. Nature 490:367–372. doi:10.1038/nature11442
-
(2012)
Nature
, vol.490
, pp. 367-372
-
-
Korkhov, V.M.1
Mireku, S.A.2
Locher, K.P.3
-
76
-
-
84876665028
-
Fate of ferrisiderophores after import across bacterial outer membranes: Different iron release strategies are observed in the cytoplasm or periplasm depending on the siderophore pathways
-
Schalk IJ, Guillon L (2013) Fate of ferrisiderophores after import across bacterial outer membranes: different iron release strategies are observed in the cytoplasm or periplasm depending on the siderophore pathways. Amino Acids 44:1267–1277. doi:10.1007/s00726-013-1468-2
-
(2013)
Amino Acids
, vol.44
, pp. 1267-1277
-
-
Schalk, I.J.1
Guillon, L.2
-
77
-
-
84933510945
-
Structure and mechanism of the siderophore-interacting protein from the fuscachelin gene cluster of Thermobifida fusca
-
Li K, Chen W-H, Bruner SD (2015) Structure and mechanism of the siderophore-interacting protein from the fuscachelin gene cluster of Thermobifida fusca. Biochemistry 54:3989–4000. doi:10.1021/acs.biochem.5b00354
-
(2015)
Biochemistry
, vol.54
, pp. 3989-4000
-
-
Li, K.1
Chen, W.-H.2
Bruner, S.D.3
-
78
-
-
23744479843
-
In vitro characterization of salmochelin and enterobactin trilactone hydrolases IroD, IroE, and Fes
-
Lin H, Fischbach MA, Liu DR, Walsh CT (2005) In vitro characterization of salmochelin and enterobactin trilactone hydrolases IroD, IroE, and Fes. J Am Chem Soc 127:11075–11084. doi:10.1021/ja0522027
-
(2005)
J am Chem Soc
, vol.127
, pp. 11075-11084
-
-
Lin, H.1
Fischbach, M.A.2
Liu, D.R.3
Walsh, C.T.4
-
79
-
-
0028467772
-
Structure of a unique twofold symmetric haem-binding site
-
Frolow F, Kalb AJ, Yariv J (1994) Structure of a unique twofold symmetric haem-binding site. Nat Struct Biol 1:453–460. doi:10.1038/nsb0794-453
-
(1994)
Nat Struct Biol
, vol.1
, pp. 453-460
-
-
Frolow, F.1
Kalb, A.J.2
Yariv, J.3
-
80
-
-
84937780279
-
Recent developments in understanding the iron acquisition strategies of gram positive pathogens
-
Sheldon JR, Heinrichs DE (2015) Recent developments in understanding the iron acquisition strategies of gram positive pathogens. FEMS Microbiol Rev 39:592–630. doi:10.1093/femsre/fuv009
-
(2015)
FEMS Microbiol Rev
, vol.39
, pp. 592-630
-
-
Sheldon, J.R.1
Heinrichs, D.E.2
-
81
-
-
0034718606
-
Microbial iron transport via a siderophore shuttle: A membrane ion transport paradigm
-
Stintzi A, Barnes C, Xu J, Raymond KN (2000) Microbial iron transport via a siderophore shuttle: a membrane ion transport paradigm. Proc Natl Acad Sci U S A 97:10691–10696. doi:10.1073/pnas.200318797
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 10691-10696
-
-
Stintzi, A.1
Barnes, C.2
Xu, J.3
Raymond, K.N.4
-
82
-
-
84882747810
-
Gram-positive siderophore-shuttle with iron-exchange from Fe-siderophore to apo-siderophore by Bacillus cereus YxeB
-
Fukushima T, Allred BE, Sia AK, Nichiporuk R, Andersen UN, Raymond KN (2013) Gram-positive siderophore-shuttle with iron-exchange from Fe-siderophore to apo-siderophore by Bacillus cereus YxeB. Proc Natl Acad Sci U S A 110:13821–13826. doi:10.1073/pnas. 1304235110
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, pp. 13821-13826
-
-
Fukushima, T.1
Allred, B.E.2
Sia, A.K.3
Nichiporuk, R.4
Andersen, U.N.5
Raymond, K.N.6
-
83
-
-
84913600844
-
Direct evidence of iron uptake by the Gram-positive siderophore-shuttle mechanism without iron reduction
-
Fukushima T, Allred BE, Raymond KN (2014) Direct evidence of iron uptake by the Gram-positive siderophore-shuttle mechanism without iron reduction. ACS Chem Biol 9:2092–2100. doi:10.1021/cb500319n
-
(2014)
ACS Chem Biol
, vol.9
, pp. 2092-2100
-
-
Fukushima, T.1
Allred, B.E.2
Raymond, K.N.3
-
84
-
-
77949545789
-
Siderophores from neighboring organisms promote the growth of uncultured bacteria
-
D’Onofrio A, Crawford JM, Stewart EJ, Witt K, Gavrish E, Epstein S, Clardy J, Lewis K (2010) Siderophores from neighboring organisms promote the growth of uncultured bacteria. Chem Biol 17:254–264. doi:10.1016/j.chembiol.2010.02.010
-
(2010)
Chem Biol
, vol.17
, pp. 254-264
-
-
D’Onofrio, A.1
Crawford, J.M.2
Stewart, E.J.3
Witt, K.4
Gavrish, E.5
Epstein, S.6
Clardy, J.7
Lewis, K.8
-
85
-
-
35448937302
-
Mechanism of action of sideromycins
-
Knusel F, Nuesch J (1965) Mechanism of action of sideromycins. Nature 206:674–676. doi:10.1038/206674a0
-
(1965)
Nature
, vol.206
, pp. 674-676
-
-
Knusel, F.1
Nuesch, J.2
-
86
-
-
33744744409
-
Albomycin uptake via a ferric hydroxamate transport system of Streptococcus pneumoniae R6
-
Pramanik A, Braun V (2006) Albomycin uptake via a ferric hydroxamate transport system of Streptococcus pneumoniae R6. J Bacteriol 188:3878–3886. doi:10.1128/jb.00205-06
-
(2006)
J Bacteriol
, vol.188
, pp. 3878-3886
-
-
Pramanik, A.1
Braun, V.2
-
87
-
-
33744725409
-
Recent studies on albomycin, a new antibiotic
-
doi:10. 1136/bmj.2.4949.1177
-
Gause GF (1955) Recent studies on albomycin, a new antibiotic. BMJ 2:1177–1179. doi:10. 1136/bmj.2.4949.1177
-
(1955)
BMJ
, vol.2
, pp. 1177-1179
-
-
Gause, G.F.1
-
88
-
-
84868087343
-
Biosynthesis of albomycin δ(2) provides a template for assembling siderophore and aminoacyl-tRNA synthetase inhibitor conjugates
-
Zeng Y, Kulkarni A, Yang Z, Patil PB, Zhou W, Chi X, Van Lanen S, Chen S (2012) Biosynthesis of albomycin δ(2) provides a template for assembling siderophore and aminoacyl-tRNA synthetase inhibitor conjugates. ACS Chem Biol 7:1565–1575. doi:10. 1021/cb300173x
-
(2012)
ACS Chem Biol
, vol.7
, pp. 1565-1575
-
-
Zeng, Y.1
Kulkarni, A.2
Yang, Z.3
Patil, P.B.4
Zhou, W.5
Chi, X.6
van Lanen, S.7
Chen, S.8
-
89
-
-
84953896573
-
A branch point of Streptomyces sulfur amino acid metabolism controls the production of albomycin
-
Kulkarni A, Zeng Y, Zhou W, Van Lanen S, Zhang W, Chen S (2015) A branch point of Streptomyces sulfur amino acid metabolism controls the production of albomycin. Appl Environ Microbiol 82:467–477. doi:10.1128/aem.02517-15
-
(2015)
Appl Environ Microbiol
, vol.82
, pp. 467-477
-
-
Kulkarni, A.1
Zeng, Y.2
Zhou, W.3
van Lanen, S.4
Zhang, W.5
Chen, S.6
-
90
-
-
0034525966
-
A potent seryl tRNA synthetase inhibitor SB-217452 isolated from a Streptomyces species
-
Stefanska AL, Fulston M, Houge-Frydrych CS, Jones JJ, Warr SR (2000) A potent seryl tRNA synthetase inhibitor SB-217452 isolated from a Streptomyces species. J Antibiot 53:1346–1353. doi:10.7164/antibiotics.53.1346
-
(2000)
J Antibiot
, vol.53
, pp. 1346-1353
-
-
Stefanska, A.L.1
Fulston, M.2
Houge-Frydrych, C.S.3
Jones, J.J.4
Warr, S.R.5
-
91
-
-
70350307194
-
Characterization of two seryl-tRNA synthetases in albomycin-producing Streptomyces sp. Strain ATCC 700974
-
Zeng Y, Roy H, Patil PB, Ibba M, Chen S (2009) Characterization of two seryl-tRNA synthetases in albomycin-producing Streptomyces sp. strain ATCC 700974. Antimicrob Agents Chemother 53:4619–4627. doi:10.1128/aac.00782-09
-
(2009)
Antimicrob Agents Chemother
, vol.53
, pp. 4619-4627
-
-
Zeng, Y.1
Roy, H.2
Patil, P.B.3
Ibba, M.4
Chen, S.5
-
92
-
-
0034079929
-
Crystal structure of the antibiotic albomycin in complex with the outer membrane transporter FhuA
-
Ferguson AD, Braun V, Fiedler HP, Coulton JW, Diederichs K, Welte W (2000) Crystal structure of the antibiotic albomycin in complex with the outer membrane transporter FhuA. Protein Sci 9:956–963. doi:10.1110/ps.9.5.956
-
(2000)
Protein Sci
, vol.9
, pp. 956-963
-
-
Ferguson, A.D.1
Braun, V.2
Fiedler, H.P.3
Coulton, J.W.4
Diederichs, K.5
Welte, W.6
-
93
-
-
0037134502
-
X-ray crystallographic structures of the Escherichia coli periplasmic protein FhuD bound to hydroxamate-type siderophores and the antibiotic albomycin
-
Clarke TE, Braun V, Winkelmann G, Tari LW, Vogel HJ (2002) X-ray crystallographic structures of the Escherichia coli periplasmic protein FhuD bound to hydroxamate-type siderophores and the antibiotic albomycin. J Biol Chem 277:13966–13972. doi:10.1074/jbc.M109385200
-
(2002)
J Biol Chem
, vol.277
, pp. 13966-13972
-
-
Clarke, T.E.1
Braun, V.2
Winkelmann, G.3
Tari, L.W.4
Vogel, H.J.5
-
94
-
-
0020627683
-
Intracellular activation of albomycin in Escherichia coli and Salmonella typhimurium
-
Braun V, Gunthner K, Hantke K, Zimmermann L (1983) Intracellular activation of albomycin in Escherichia coli and Salmonella typhimurium. J Bacteriol 156:308–315
-
(1983)
J Bacteriol
, vol.156
, pp. 308-315
-
-
Braun, V.1
Gunthner, K.2
Hantke, K.3
Zimmermann, L.4
-
95
-
-
34548507968
-
Albomycin is an effective antibiotic, as exemplified with Yersinia enterocolitica and Streptococcus pneumoniae
-
Pramanik A, Stroeher UH, Krejci J, Standish AJ, Bohn E, Paton JC, Autenrieth IB, Braun V (2007) Albomycin is an effective antibiotic, as exemplified with Yersinia enterocolitica and Streptococcus pneumoniae. Int J Med Microbiol 297:459–469. doi:10.1016/j.ijmm.2007.03.002
-
(2007)
Int J Med Microbiol
, vol.297
, pp. 459-469
-
-
Pramanik, A.1
Stroeher, U.H.2
Krejci, J.3
Standish, A.J.4
Bohn, E.5
Paton, J.C.6
Autenrieth, I.B.7
Braun, V.8
-
96
-
-
0029094662
-
Salmycin A–D, antibiotika aus Streptomyces violaceus, DSM 8286, mit siderophor-aminoglycosid-struktur
-
Vértesy L, Aretz W, Fehlhaber H-W, Kogler H (1995) Salmycin A–D, antibiotika aus Streptomyces violaceus, DSM 8286, mit siderophor-aminoglycosid-struktur. Helv Chim Acta 78:46–60. doi:10.1002/hlca.19950780105
-
(1995)
Helv Chim Acta
, vol.78
, pp. 46-60
-
-
Vértesy, L.1
Aretz, W.2
Fehlhaber, H.-W.3
Kogler, H.4
-
97
-
-
0022632136
-
Stoffwechselprodukte von mikroorganismen. 233. Mitteilung. Danoxamin, der eisenbindende teil des sideromycin-antibioticums danomycin
-
Huber P, Leuenberger H, Keller-Schierlein W (1986) Stoffwechselprodukte von mikroorganismen. 233. Mitteilung. Danoxamin, der eisenbindende teil des sideromycin-antibioticums danomycin. Helv Chim Acta 69:236–245. doi:10.1002/hlca.19860690128
-
(1986)
Helv Chim Acta
, vol.69
, pp. 236-245
-
-
Huber, P.1
Leuenberger, H.2
Keller-Schierlein, W.3
-
98
-
-
78651158803
-
Danomycin, a new antibiotic
-
Tsukiura H, Okanishi M, Ohmori T, Koshiyama H, Miyaki T, Kitazima H, Kawaguchi H (1964) Danomycin, a new antibiotic. J Antibiot 17:39–47
-
(1964)
J Antibiot
, vol.17
, pp. 39-47
-
-
Tsukiura, H.1
Okanishi, M.2
Ohmori, T.3
Koshiyama, H.4
Miyaki, T.5
Kitazima, H.6
Kawaguchi, H.7
-
99
-
-
67651247598
-
Is drug release necessary for antimicrobial activity of siderophore-drug conjugates? Syntheses and biological studies of the naturally occurring salmycin “Trojan horse” antibiotics and synthetic desferridanoxamine-antibiotic conjugates
-
Wencewicz TA, M€ollmann U, Long TE, Miller MJ (2009) Is drug release necessary for antimicrobial activity of siderophore-drug conjugates? Syntheses and biological studies of the naturally occurring salmycin “Trojan horse” antibiotics and synthetic desferridanoxamine-antibiotic conjugates. Biometals 22:633–648. doi:10.1007/s10534-009-9218-3
-
(2009)
Biometals
, vol.22
, pp. 633-648
-
-
Wencewicz, T.A.1
M€Ollmann, U.2
Long, T.E.3
Miller, M.J.4
-
100
-
-
33747074333
-
Identification of genes involved in siderophore transport in Streptomyces coelicolor A3(2)
-
Bunet R, Brock A, Rexer HU, Takano E (2006) Identification of genes involved in siderophore transport in Streptomyces coelicolor A3(2). FEMS Microbiol Lett 262:57–64. doi:10.1111/j.1574-6968.2006.00362.x
-
(2006)
FEMS Microbiol Lett
, vol.262
, pp. 57-64
-
-
Bunet, R.1
Brock, A.2
Rexer, H.U.3
Takano, E.4
-
102
-
-
84866108987
-
Staphylococcus aureus FhuD2 is involved in the early phase of staphylococcal dissemination and generates protective immunity in mice
-
Mishra RP, Mariotti P, Fiaschi L, Nosari S, Maccari S, Liberatori S, Fontana MR, Pezzicoli A, De Falco MG, Falugi F, Altindis E, Serruto D, Grandi G, Bagnoli F (2012) Staphylococcus aureus FhuD2 is involved in the early phase of staphylococcal dissemination and generates protective immunity in mice. J Infect Dis 206:1041–1049. doi:10.1093/infdis/jis463
-
(2012)
J Infect Dis
, vol.206
, pp. 1041-1049
-
-
Mishra, R.P.1
Mariotti, P.2
Fiaschi, L.3
Nosari, S.4
Maccari, S.5
Liberatori, S.6
Fontana, M.R.7
Pezzicoli, A.8
de Falco, M.G.9
Falugi, F.10
Altindis, E.11
Serruto, D.12
Grandi, G.13
Bagnoli, F.14
-
103
-
-
84919467117
-
Deferoxamine mesylate enhances virulence of community-associated methicillin resistant Staphylococcus aureus
-
Arifin AJ, Hannauer M, Welch I, Heinrichs DE (2014) Deferoxamine mesylate enhances virulence of community-associated methicillin resistant Staphylococcus aureus. Microbes Infect 16:967–972. doi:10.1016/j.micinf.2014.09.003
-
(2014)
Microbes Infect
, vol.16
, pp. 967-972
-
-
Arifin, A.J.1
Hannauer, M.2
Welch, I.3
Heinrichs, D.E.4
-
104
-
-
21044449406
-
A widely distributed bacterial pathway for siderophore biosynthesis independent of nonribosomal peptide synthetases
-
Challis GL (2005) A widely distributed bacterial pathway for siderophore biosynthesis independent of nonribosomal peptide synthetases. ChemBioChem 6:601–611. doi:10.1002/cbic.200400283
-
(2005)
Chembiochem
, vol.6
, pp. 601-611
-
-
Challis, G.L.1
-
105
-
-
0034637519
-
Total synthesis of the siderophore danoxamine
-
Roosenberg II JM, Miller MJ (2000) Total synthesis of the siderophore danoxamine. J Org Chem 65:4833–4838. doi:10.1021/jo000050m
-
(2000)
J Org Chem
, vol.65
, pp. 4833-4838
-
-
Roosenberg, J.M.1
Miller, M.J.2
-
106
-
-
0037132597
-
Total synthesis of desferrisalmycin B
-
Dong L, Roosenberg II JM, Miller MJ (2002) Total synthesis of desferrisalmycin B. J Am Chem Soc 124(50):15001–15005. doi:10.1021/ja028386w
-
(2002)
J am Chem Soc
, vol.124
, Issue.50
, pp. 15001-15005
-
-
Dong, L.1
Roosenberg, J.M.2
Miller, M.J.3
-
107
-
-
34250968659
-
Metabolites of actinomycetes. 28. “In vitro” resistance to ferrimycin
-
Bachmann E, Zaehner H (1961) Metabolites of actinomycetes. 28. “In vitro” resistance to ferrimycin. Arch Mikrobiol 38:326–338
-
(1961)
Arch Mikrobiol
, vol.38
, pp. 326-338
-
-
Bachmann, E.1
Zaehner, H.2
-
108
-
-
0013834496
-
Constitution of ferrimycin A1
-
Bickel H, Mertens P, Prelog V, Seibl J, Walser A (1965) Constitution of ferrimycin A1. Antimicrob Agents Chemother 5:951–957
-
(1965)
Antimicrob Agents Chemother
, vol.5
, pp. 951-957
-
-
Bickel, H.1
Mertens, P.2
Prelog, V.3
Seibl, J.4
Walser, A.5
-
109
-
-
3242836200
-
Stoffwechselprodukte von mikroorganismen – 53: Ueber die konstitution von ferrimycin A1
-
Bickel H, Mertens P, Prelog V, Seibl J, Walser A (1966) Stoffwechselprodukte von mikroorganismen – 53: ueber die konstitution von ferrimycin A1. Tetrahedron 22:171–179. doi:10.1016/S0040-4020(01)82182-7
-
(1966)
Tetrahedron
, vol.22
, pp. 171-179
-
-
Bickel, H.1
Mertens, P.2
Prelog, V.3
Seibl, J.4
Walser, A.5
-
110
-
-
35448931532
-
Novel whole-cell antibiotic biosensors for compound discovery
-
Urban A, Eckermann S, Fast B, Metzger S, Gehling M, Ziegelbauer K, Rübsamen-Waigmann H, Freiberg C (2007) Novel whole-cell antibiotic biosensors for compound discovery. Appl Environ Microbiol 73:6436–6443. doi:10.1128/aem.00586-07
-
(2007)
Appl Environ Microbiol
, vol.73
, pp. 6436-6443
-
-
Urban, A.1
Eckermann, S.2
Fast, B.3
Metzger, S.4
Gehling, M.5
Ziegelbauer, K.6
Rübsamen-Waigmann, H.7
Freiberg, C.8
-
111
-
-
0025157461
-
Ferrioxamine transport mutants and the identification of the ferrioxamine receptor protein (FoxA) in Erwinia herbicola (Enterobacter agglomerans)
-
Berner I, Winkelmann G (1990) Ferrioxamine transport mutants and the identification of the ferrioxamine receptor protein (FoxA) in Erwinia herbicola (Enterobacter agglomerans). Biol Met 2:197–202. doi:10.1007/BF01141359
-
(1990)
Biol Met
, vol.2
, pp. 197-202
-
-
Berner, I.1
Winkelmann, G.2
-
112
-
-
35449005387
-
Ferrimycin A, a new iron-containing antibiotic
-
Sackmann W, Reusser P, Neipp L, Kradolfer F, Gross F (1962) Ferrimycin A, a new iron-containing antibiotic. Antibiot Chemother 12:34–45
-
(1962)
Antibiot Chemother
, vol.12
, pp. 34-45
-
-
Sackmann, W.1
Reusser, P.2
Neipp, L.3
Kradolfer, F.4
Gross, F.5
-
113
-
-
84870918230
-
Ribosomally synthesized and post-translationally modified peptide natural products: Overview and recommendations for a universal nomenclature
-
Arnison PG, Bibb MJ, Bierbaum G, Bowers AA, Bugni TS, Bulaj G, Camarero JA, Campopiano DJ, Challis GL, Clardy J, Cotter PD, Craik DJ, Dawson M, Dittmann E, Donadio S, Dorrestein PC, Entian K-D, Fischbach MA, Garavelli JS, Goransson U, Gruber CW, Haft DH, Hemscheidt TK, Hertweck C, Hill C, Horswill AR, Jaspars M, Kelly WL, Klinman JP, Kuipers OP, Link AJ, Liu W, Marahiel MA, Mitchell DA, Moll GN, Moore BS, Muller R, Nair SK, Nes IF, Norris GE, Olivera BM, Onaka H, Patchett ML, Piel J, Reaney MJT, Rebuffat S, Ross RP, Sahl H-G, Schmidt EW, Selsted ME, Severinov K, Shen B, Sivonen K, Smith L, Stein T, Sussmuth RD, Tagg JR, Tang G-L, Truman AW, Vederas JC, Walsh CT, Walton JD, Wenzel SC, Willey JM, van der Donk WA (2013) Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature. Nat Prod Rep 30:108–160. doi:10.1039/C2NP20085F
-
(2013)
Nat Prod Rep
, vol.30
, pp. 108-160
-
-
Arnison, P.G.1
Bibb, M.J.2
Bierbaum, G.3
Bowers, A.A.4
Bugni, T.S.5
Bulaj, G.6
Camarero, J.A.7
Campopiano, D.J.8
Challis, G.L.9
Clardy, J.10
Cotter, P.D.11
Craik, D.J.12
Dawson, M.13
Dittmann, E.14
Donadio, S.15
Dorrestein, P.C.16
Entian, K.-D.17
Fischbach, M.A.18
Garavelli, J.S.19
Goransson, U.20
Gruber, C.W.21
Haft, D.H.22
Hemscheidt, T.K.23
Hertweck, C.24
Hill, C.25
Horswill, A.R.26
Jaspars, M.27
Kelly, W.L.28
Klinman, J.P.29
Kuipers, O.P.30
Link, A.J.31
Liu, W.32
Marahiel, M.A.33
Mitchell, D.A.34
Moll, G.N.35
Moore, B.S.36
Muller, R.37
Nair, S.K.38
Nes, I.F.39
Norris, G.E.40
Olivera, B.M.41
Onaka, H.42
Patchett, M.L.43
Piel, J.44
Reaney, M.J.T.45
Rebuffat, S.46
Ross, R.P.47
Sahl, H.-G.48
Schmidt, E.W.49
Selsted, M.E.50
Severinov, K.51
Shen, B.52
Sivonen, K.53
Smith, L.54
Stein, T.55
Sussmuth, R.D.56
Tagg, J.R.57
Tang, G.-L.58
Truman, A.W.59
Vederas, J.C.60
Walsh, C.T.61
Walton, J.D.62
Wenzel, S.C.63
Willey, J.M.64
van der Donk, W.A.65
more..
-
114
-
-
34447528296
-
Microcins, gene-encoded antibacterial peptides from enterobacteria
-
Duquesne S, Destoumieux-Garzon D, Peduzzi J, Rebuffat S (2007) Microcins, gene-encoded antibacterial peptides from enterobacteria. Nat Prod Rep 24:708–734. doi:10.1039/b516237h
-
(2007)
Nat Prod Rep
, vol.24
, pp. 708-734
-
-
Duquesne, S.1
Destoumieux-Garzon, D.2
Peduzzi, J.3
Rebuffat, S.4
-
115
-
-
3142543798
-
Siderophore peptide, a new type of post-translationally modified antibacterial peptide with potent activity
-
Thomas X, Destoumieux-Garzon D, Peduzzi J, Afonso C, Blond A, Birlirakis N, Goulard C, Dubost L, Thai R, Tabet JC, Rebuffat S (2004) Siderophore peptide, a new type of post-translationally modified antibacterial peptide with potent activity. J Biol Chem 279:28233–28242. doi:10.1074/jbc.M400228200
-
(2004)
J Biol Chem
, vol.279
, pp. 28233-28242
-
-
Thomas, X.1
Destoumieux-Garzon, D.2
Peduzzi, J.3
Afonso, C.4
Blond, A.5
Birlirakis, N.6
Goulard, C.7
Dubost, L.8
Thai, R.9
Tabet, J.C.10
Rebuffat, S.11
-
116
-
-
36448952357
-
Biosynthetic tailoring of microcin E492m: Post-translational modification affords an antibacterial siderophore peptide conjugate
-
Nolan EM, Fischbach MA, Koglin A, Walsh CT (2007) Biosynthetic tailoring of microcin E492m: post-translational modification affords an antibacterial siderophore peptide conjugate. J Am Chem Soc 129:14336–14347. doi:10.1021/ja074650f
-
(2007)
J am Chem Soc
, vol.129
, pp. 14336-14347
-
-
Nolan, E.M.1
Fischbach, M.A.2
Koglin, A.3
Walsh, C.T.4
-
117
-
-
50849105102
-
Investigations of the MceIJ-catalyzed posttranslational modification of the microcin E492 C-terminus: Linkage of ribosomal and nonribosomal peptides to form “Trojan horse” antibiotics
-
Nolan EM, Walsh CT (2008) Investigations of the MceIJ-catalyzed posttranslational modification of the microcin E492 C-terminus: linkage of ribosomal and nonribosomal peptides to form “Trojan horse” antibiotics. Biochemistry 47:9289–9299. doi:10.1021/bi800826j
-
(2008)
Biochemistry
, vol.47
, pp. 9289-9299
-
-
Nolan, E.M.1
Walsh, C.T.2
-
118
-
-
84878324193
-
Tetroazolemycins A and B, two new oxazole-thiazole siderophores from deep-sea Streptomyces olivaceus FXJ8.012
-
Liu N, Shang F, Xi L, Huang Y (2013) Tetroazolemycins A and B, two new oxazole-thiazole siderophores from deep-sea Streptomyces olivaceus FXJ8.012. Mar Drugs 11:1524–1533. doi:10.3390/md11051524
-
(2013)
Mar Drugs
, vol.11
, pp. 1524-1533
-
-
Liu, N.1
Shang, F.2
Xi, L.3
Huang, Y.4
-
119
-
-
79961121513
-
Klebsiella pneumoniae yersiniabactin promotes respiratory tract infection through evasion of lipocalin 2
-
Bachman MA, Oyler JE, Burns SH, Caza M, Lepine F, Dozois CM, Weiser JN (2011) Klebsiella pneumoniae yersiniabactin promotes respiratory tract infection through evasion of lipocalin 2. Infect Immun 79:3309–3316. doi:10.1128/iai.05114-11
-
(2011)
Infect Immun
, vol.79
, pp. 3309-3316
-
-
Bachman, M.A.1
Oyler, J.E.2
Burns, S.H.3
Caza, M.4
Lepine, F.5
Dozois, C.M.6
Weiser, J.N.7
-
120
-
-
84857527566
-
Pyochelin, a siderophore of Pseudomonas aeruginosa: Physicochemical characterization of the iron(iii), copper(ii) and zinc(ii) complexes
-
Brandel J, Humbert N, Elhabiri M, Schalk IJ, Mislin GLA, Albrecht-Gary A-M (2012) Pyochelin, a siderophore of Pseudomonas aeruginosa: physicochemical characterization of the iron(iii), copper(ii) and zinc(ii) complexes. Dalton Trans 41:2820–2834. doi:10.1039/C1DT11804H
-
(2012)
Dalton Trans
, vol.41
, pp. 2820-2834
-
-
Brandel, J.1
Humbert, N.2
Elhabiri, M.3
Schalk, I.J.4
Mislin, G.L.A.5
Albrecht-Gary, A.-M.6
-
121
-
-
84856299226
-
Biosynthesis and function of gliotoxin in Aspergillus fumigatus
-
Scharf DH, Heinekamp T, Remme N, Hortschansky P, Brakhage AA, Hertweck C (2012) Biosynthesis and function of gliotoxin in Aspergillus fumigatus. Appl Microbiol Biotechnol 93:467–472. doi:10.1007/s00253-011-3689-1
-
(2012)
Appl Microbiol Biotechnol
, vol.93
, pp. 467-472
-
-
Scharf, D.H.1
Heinekamp, T.2
Remme, N.3
Hortschansky, P.4
Brakhage, A.A.5
Hertweck, C.6
-
123
-
-
84872850695
-
Siderophore conjugates
-
Page MG (2013) Siderophore conjugates. Ann N Y Acad Sci 1277:115–126. doi:10.1111/nyas.12024
-
(2013)
Ann N Y Acad Sci
, vol.1277
, pp. 115-126
-
-
Page, M.G.1
-
124
-
-
84863393586
-
Exploiting bacterial iron acquisition: Siderophore conjugates
-
Ji C, Juarez-Hernandez RE, Miller MJ (2012) Exploiting bacterial iron acquisition: siderophore conjugates. Future Med Chem 4:297–313. doi:10.4155/fmc.11.191
-
(2012)
Future Med Chem
, vol.4
, pp. 297-313
-
-
Ji, C.1
Juarez-Hernandez, R.E.2
Miller, M.J.3
-
125
-
-
84905299821
-
Siderophore–drug complexes: Potential medicinal applications of the ‘Trojan horse’ strategy
-
Górska A, Sloderbach A, Marszałł MP (2014) Siderophore–drug complexes: potential medicinal applications of the ‘Trojan horse’ strategy. Trends Pharmacol Sci 35:442–449. doi:10.1016/j.tips.2014.06.007
-
(2014)
Trends Pharmacol Sci
, vol.35
, pp. 442-449
-
-
Górska, A.1
Sloderbach, A.2
Marszałł, M.P.3
-
126
-
-
84896879592
-
Siderophore-dependent iron uptake systems as gates for antibiotic Trojan horse strategies against Pseudomonas aeruginosa
-
Mislin GL, Schalk IJ (2014) Siderophore-dependent iron uptake systems as gates for antibiotic Trojan horse strategies against Pseudomonas aeruginosa. Metallomics 6:408–420. doi:10.1039/c3mt00359k
-
(2014)
Metallomics
, vol.6
, pp. 408-420
-
-
Mislin, G.L.1
Schalk, I.J.2
-
127
-
-
84965014151
-
Microbial siderophore-based iron assimilation and therapeutic applications
-
Li K, Chen W-H, Bruner SD (2016) Microbial siderophore-based iron assimilation and therapeutic applications. Biometals 29:377–388. doi:10.1007/s10534-016-9935-3
-
(2016)
Biometals
, vol.29
, pp. 377-388
-
-
Li, K.1
Chen, W.-H.2
Bruner, S.D.3
-
128
-
-
85017495826
-
Trojan horse antibiotics – a novel way to circumvent gram-negative bacterial resistance?
-
Tillotson GS (2016) Trojan horse antibiotics – a novel way to circumvent gram-negative bacterial resistance? Infect Dis 9:45–52. doi:10.4137/idrt.s31567
-
(2016)
Infect Dis
, vol.9
, pp. 45-52
-
-
Tillotson, G.S.1
-
129
-
-
85008311832
-
Design, synthesis and microbiological evaluation of ampicillin-tetramic acid hybrid antibiotics
-
Cherian PT, Deshpande A, Cheramie MN, Bruhn DF, Hurdle JG, Lee RE (2017) Design, synthesis and microbiological evaluation of ampicillin-tetramic acid hybrid antibiotics. J Antibiot 70:65–72. doi:10.1038/ja.2016.52
-
(2017)
J Antibiot
, vol.70
, pp. 65-72
-
-
Cherian, P.T.1
Deshpande, A.2
Cheramie, M.N.3
Bruhn, D.F.4
Hurdle, J.G.5
Lee, R.E.6
-
130
-
-
84900335969
-
Siderophore receptor-mediated uptake of lactivicin analogues in Gram-negative bacteria
-
Starr J, Brown MF, Aschenbrenner L, Caspers N, Che Y, Gerstenberger BS, Huband M, Knafels JD, Lemmon MM, Li C, McCurdy SP, McElroy E, Rauckhorst MR, Tomaras AP, Young JA, Zaniewski RP, Shanmugasundaram V, Han S (2014) Siderophore receptor-mediated uptake of lactivicin analogues in Gram-negative bacteria. J Med Chem 57:3845–3855. doi:10.1021/jm500219c
-
(2014)
J Med Chem
, vol.57
, pp. 3845-3855
-
-
Starr, J.1
Brown, M.F.2
Aschenbrenner, L.3
Caspers, N.4
Che, Y.5
Gerstenberger, B.S.6
Huband, M.7
Knafels, J.D.8
Lemmon, M.M.9
Li, C.10
McCurdy, S.P.11
McElroy, E.12
Rauckhorst, M.R.13
Tomaras, A.P.14
Young, J.A.15
Zaniewski, R.P.16
Shanmugasundaram, V.17
Han, S.18
-
131
-
-
9744232909
-
Time-related differences in the physical property profiles of oral drugs
-
Leeson PD, Davis AM (2004) Time-related differences in the physical property profiles of oral drugs. J Med Chem 47:6338–6348. https://doi.org/10.1021/jm049717d
-
(2004)
J Med Chem
, vol.47
, pp. 6338-6348
-
-
Leeson, P.D.1
Davis, A.M.2
-
132
-
-
0031684186
-
Synthesis and in vitro antibacterial activity of catechol-spiramycin conjugates
-
Poras H, Kunesch G, Barriere JC, Berthaud N, Andremont A (1998) Synthesis and in vitro antibacterial activity of catechol-spiramycin conjugates. J Antibiot 51:786–794. doi:10.7164/antibiotics.51.786
-
(1998)
J Antibiot
, vol.51
, pp. 786-794
-
-
Poras, H.1
Kunesch, G.2
Barriere, J.C.3
Berthaud, N.4
Andremont, A.5
-
133
-
-
0028793908
-
Design, synthesis, and biological evaluation of isocyanurate-based antifungal and macrolide antibiotic conjugates: Iron transport-mediated drug delivery
-
Ghosh M, Miller MJ (1995) Design, synthesis, and biological evaluation of isocyanurate-based antifungal and macrolide antibiotic conjugates: iron transport-mediated drug delivery. Bioorg Med Chem 3:1519–1525. doi:10.1016/0968-0896(95)00134-3
-
(1995)
Bioorg Med Chem
, vol.3
, pp. 1519-1525
-
-
Ghosh, M.1
Miller, M.J.2
-
134
-
-
79953034977
-
An artificial pathway to 3,4-dihydroxybenzoic acid allows generation of new aminocoumarin antibiotic recognized by catechol transporters of E. Coli
-
Alt S, Burkard N, Kulik A, Grond S, Heide L (2011) An artificial pathway to 3,4-dihydroxybenzoic acid allows generation of new aminocoumarin antibiotic recognized by catechol transporters of E. coli. Chem Biol 18:304–313. doi:10.1016/j.chembiol.2010.12.016
-
(2011)
Chem Biol
, vol.18
, pp. 304-313
-
-
Alt, S.1
Burkard, N.2
Kulik, A.3
Grond, S.4
Heide, L.5
-
135
-
-
11244258728
-
Desketoneoenactin-siderophore conjugates for Candida: Evidence of iron transport-dependent species selectivity
-
Bernier G, Girijavallabhan V, Murray A, Niyaz N, Ding P, Miller MJ, Malouin F (2005) Desketoneoenactin-siderophore conjugates for Candida: evidence of iron transport-dependent species selectivity. Antimicrob Agents Chemother 49:241–248. doi:10.1128/aac. 49.1.241-248.2005
-
(2005)
Antimicrob Agents Chemother
, vol.49
, pp. 241-248
-
-
Bernier, G.1
Girijavallabhan, V.2
Murray, A.3
Niyaz, N.4
Ding, P.5
Miller, M.J.6
Malouin, F.7
-
136
-
-
0033384172
-
Syntheses and studies of multiwarhead siderophore-5-fluorouridine conjugates
-
Lu Y, Miller MJ (1999) Syntheses and studies of multiwarhead siderophore-5-fluorouridine conjugates. Bioorg Med Chem 7:3025–3038. doi:10.1016/S0968-0896(99)00248-5
-
(1999)
Bioorg Med Chem
, vol.7
, pp. 3025-3038
-
-
Lu, Y.1
Miller, M.J.2
-
138
-
-
79951816261
-
Design, synthesis, and study of a mycobactin-artemisinin conjugate that has selective and potent activity against tuberculosis and malaria
-
Miller MJ, Walz AJ, Zhu H, Wu C, Moraski G, Mollmann U, Tristani EM, Crumbliss AL, Ferdig MT, Checkley L, Edwards RL, Boshoff HI (2011) Design, synthesis, and study of a mycobactin-artemisinin conjugate that has selective and potent activity against tuberculosis and malaria. J Am Chem Soc 133:2076–2079. doi:10.1021/ja109665t
-
(2011)
J am Chem Soc
, vol.133
, pp. 2076-2079
-
-
Miller, M.J.1
Walz, A.J.2
Zhu, H.3
Wu, C.4
Moraski, G.5
Mollmann, U.6
Tristani, E.M.7
Crumbliss, A.L.8
Ferdig, M.T.9
Checkley, L.10
Edwards, R.L.11
Boshoff, H.I.12
-
139
-
-
0030014795
-
Framework-reactive siderophore analogs as potential cell-selective drugs. Design and syntheses of trimelamol-based iron chelators
-
Ramurthy S, Miller MJ (1996) Framework-reactive siderophore analogs as potential cell-selective drugs. Design and syntheses of trimelamol-based iron chelators. J Org Chem 61:4120–4124. doi:10.1021/jo9600621
-
(1996)
J Org Chem
, vol.61
, pp. 4120-4124
-
-
Ramurthy, S.1
Miller, M.J.2
-
140
-
-
84867393274
-
Syntheses of siderophore–drug conjugates using a convergent thiol–maleimide system
-
doi:10. 1021/ml300150y
-
Juárez-Hernández RE, Miller PA, Miller MJ (2012) Syntheses of siderophore–drug conjugates using a convergent thiol–maleimide system. ACS Med Chem Lett 3:799–803. doi:10. 1021/ml300150y
-
(2012)
ACS Med Chem Lett
, vol.3
, pp. 799-803
-
-
Juárez-Hernández, R.E.1
Miller, P.A.2
Miller, M.J.3
-
141
-
-
0029962175
-
Synthesis and in vitro antibacterial activity of spermidine-based mixed catechol-and hydroxamate-containing siderophore–vancomycin conjugates
-
Ghosh M, Miller MJ (1996) Synthesis and in vitro antibacterial activity of spermidine-based mixed catechol-and hydroxamate-containing siderophore–vancomycin conjugates. Bioorg Med Chem 4:43–48. doi:10.1016/0968-0896(95)00161-1
-
(1996)
Bioorg Med Chem
, vol.4
, pp. 43-48
-
-
Ghosh, M.1
Miller, M.J.2
-
142
-
-
79952773032
-
Chemical synthesis and biological evaluation of gallidermin-siderophore conjugates
-
Yoganathan S, Sit CS, Vederas JC (2011) Chemical synthesis and biological evaluation of gallidermin-siderophore conjugates. Org Biomol Chem 9:2133–2141. doi:10.1039/c0ob00846j
-
(2011)
Org Biomol Chem
, vol.9
, pp. 2133-2141
-
-
Yoganathan, S.1
Sit, C.S.2
Vederas, J.C.3
-
143
-
-
85020376124
-
Targeted antibiotic delivery: Selective siderophore conjugation with daptomycin confers potent activity against multidrug resistant Acinetobacter baumannii both in vitro and in vivo
-
Epub ahead of print
-
Ghosh M, Miller PA, M€ollmann U, Claypool WD, Schroeder VA, Wolter WR, Suckow M, Yu H, Li S, Huang W, Zajicek J, Miller MJ (2017) Targeted antibiotic delivery: selective siderophore conjugation with daptomycin confers potent activity against multidrug resistant Acinetobacter baumannii both in vitro and in vivo. J Med Chem. doi:10.1021/acs.jmedchem. 7b00102 (Epub ahead of print)
-
(2017)
J Med Chem
-
-
Ghosh, M.1
Miller, P.A.2
M€Ollmann, U.3
Claypool, W.D.4
Schroeder, V.A.5
Wolter, W.R.6
Suckow, M.7
Yu, H.8
Li, S.9
Huang, W.10
Zajicek, J.11
Miller, M.J.12
-
144
-
-
84869207420
-
Clinically relevant Gram-negative resistance mechanisms have no effect on the efficacy of MC-1, a novel siderophore-conjugated monocarbam
-
McPherson CJ, Aschenbrenner LM, Lacey BM, Fahnoe KC, Lemmon MM, Finegan SM, Tadakamalla B, O’Donnell JP, Mueller JP, Tomaras AP (2012) Clinically relevant Gram-negative resistance mechanisms have no effect on the efficacy of MC-1, a novel siderophore-conjugated monocarbam. Antimicrob Agents Chemother 56:6334–6342. doi:10.1128/aac. 01345-12
-
(2012)
Antimicrob Agents Chemother
, vol.56
, pp. 6334-6342
-
-
McPherson, C.J.1
Aschenbrenner, L.M.2
Lacey, B.M.3
Fahnoe, K.C.4
Lemmon, M.M.5
Finegan, S.M.6
Tadakamalla, B.7
O’Donnell, J.P.8
Mueller, J.P.9
Tomaras, A.P.10
-
145
-
-
0025172945
-
Synthesis and structure-activity relationships of monocarbams leading to U-78608
-
Barbachyn MR, Tuominen TC (1990) Synthesis and structure-activity relationships of monocarbams leading to U-78608. J Antibiot 43:1199–1203. doi:10.7164/antibiotics.43.1199
-
(1990)
J Antibiot
, vol.43
, pp. 1199-1203
-
-
Barbachyn, M.R.1
Tuominen, T.C.2
-
146
-
-
84859602519
-
In vitro activity of the siderophore monosulfactam BAL30072 against meropenem-non-susceptible Acinetobacter baumannii
-
Higgins PG, Stefanik D, Page MG, Hackel M, Seifert H (2012) In vitro activity of the siderophore monosulfactam BAL30072 against meropenem-non-susceptible Acinetobacter baumannii. J Antimicrob Chemother 67:1167–1169. doi:10.1093/jac/dks009
-
(2012)
J Antimicrob Chemother
, vol.67
, pp. 1167-1169
-
-
Higgins, P.G.1
Stefanik, D.2
Page, M.G.3
Hackel, M.4
Seifert, H.5
-
147
-
-
84877127230
-
Combined effects of the siderophore monosulfactam BAL30072 and carbapenems on multidrug-resistant Gram-negative bacilli
-
Hofer B, Dantier C, Gebhardt K, Desarbre E, Schmitt-Hoffmann A, Page MG (2013) Combined effects of the siderophore monosulfactam BAL30072 and carbapenems on multidrug-resistant Gram-negative bacilli. J Antimicrob Chemother 68:1120–1129. doi:10. 1093/jac/dks527
-
(2013)
J Antimicrob Chemother
, vol.68
, pp. 1120-1129
-
-
Hofer, B.1
Dantier, C.2
Gebhardt, K.3
Desarbre, E.4
Schmitt-Hoffmann, A.5
Page, M.G.6
-
148
-
-
84884700230
-
In vitro activity of the novel monosulfactam BAL30072 alone and in combination with meropenem versus a diverse collection of important Gram-negative pathogens
-
Hornsey M, Phee L, Stubbings W, Wareham DW (2013) In vitro activity of the novel monosulfactam BAL30072 alone and in combination with meropenem versus a diverse collection of important Gram-negative pathogens. Int J Antimicrob Agents 42:343–346. doi:10.1016/j.ijantimicag.2013.05.010
-
(2013)
Int J Antimicrob Agents
, vol.42
, pp. 343-346
-
-
Hornsey, M.1
Phee, L.2
Stubbings, W.3
Wareham, D.W.4
-
149
-
-
84902082853
-
In vitro activity of the siderophore monosulfactam BAL30072 against contemporary Gram-negative pathogens from New York City, including multidrug-resistant isolates
-
Landman D, Singh M, El-Imad B, Miller E, Win T, Quale J (2014) In vitro activity of the siderophore monosulfactam BAL30072 against contemporary Gram-negative pathogens from New York City, including multidrug-resistant isolates. Int J Antimicrob Agents 43:527–532. doi:10.1016/j.ijantimicag.2014.02.017
-
(2014)
Int J Antimicrob Agents
, vol.43
, pp. 527-532
-
-
Landman, D.1
Singh, M.2
El-Imad, B.3
Miller, E.4
Win, T.5
Quale, J.6
-
150
-
-
77950215859
-
Activity of the siderophore monobactam BAL30072 against multiresistant non-fermenters
-
Mushtaq S, Warner M, Livermore D (2010) Activity of the siderophore monobactam BAL30072 against multiresistant non-fermenters. J Antimicrob Chemother 65:266–270. doi:10.1093/jac/dkp425
-
(2010)
J Antimicrob Chemother
, vol.65
, pp. 266-270
-
-
Mushtaq, S.1
Warner, M.2
Livermore, D.3
-
151
-
-
77952614275
-
In vitro properties of BAL30072, a novel siderophore sulfactam with activity against multiresistant gram-negative bacilli
-
Page MG, Dantier C, Desarbre E (2010) In vitro properties of BAL30072, a novel siderophore sulfactam with activity against multiresistant gram-negative bacilli. Antimicrob Agents Chemother 54:2291–2302. doi:10.1128/aac.01525-09
-
(2010)
Antimicrob Agents Chemother
, vol.54
, pp. 2291-2302
-
-
Page, M.G.1
Dantier, C.2
Desarbre, E.3
-
152
-
-
79952795119
-
In vivo and in vitro activity of the siderophore monosulfactam BAL30072 against Acinetobacter baumannii
-
Russo TA, Page MG, Beanan JM, Olson R, Hujer AM, Hujer KM, Jacobs M, Bajaksouzian S, Endimiani A, Bonomo RA (2011) In vivo and in vitro activity of the siderophore monosulfactam BAL30072 against Acinetobacter baumannii. J Antimicrob Chemother 66:867–873. doi:10.1093/jac/dkr013
-
(2011)
J Antimicrob Chemother
, vol.66
, pp. 867-873
-
-
Russo, T.A.1
Page, M.G.2
Beanan, J.M.3
Olson, R.4
Hujer, A.M.5
Hujer, K.M.6
Jacobs, M.7
Bajaksouzian, S.8
Endimiani, A.9
Bonomo, R.A.10
-
153
-
-
84876213849
-
Involvement of Fe uptake systems and AmpC beta-lactamase in susceptibility to the siderophore monosulfactam BAL30072 in Pseudomonas aeruginosa
-
van Delden C, Page MG, Kohler T (2013) Involvement of Fe uptake systems and AmpC beta-lactamase in susceptibility to the siderophore monosulfactam BAL30072 in Pseudomonas aeruginosa. Antimicrob Agents Chemother 57:2095–2102. doi:10.1128/aac.02474-12
-
(2013)
Antimicrob Agents Chemother
, vol.57
, pp. 2095-2102
-
-
van Delden, C.1
Page, M.G.2
Kohler, T.3
-
154
-
-
84882330931
-
Adaptation-based resistance to siderophore-conjugated antibacterial agents by Pseudomonas aeruginosa
-
Tomaras AP, Crandon JL, McPherson CJ, Banevicius MA, Finegan SM, Irvine RL, Brown MF, O’Donnell JP, Nicolau DP (2013) Adaptation-based resistance to siderophore-conjugated antibacterial agents by Pseudomonas aeruginosa. Antimicrob Agents Chemother 57:4197–4207. doi:10.1128/aac.00629-13
-
(2013)
Antimicrob Agents Chemother
, vol.57
, pp. 4197-4207
-
-
Tomaras, A.P.1
Crandon, J.L.2
McPherson, C.J.3
Banevicius, M.A.4
Finegan, S.M.5
Irvine, R.L.6
Brown, M.F.7
O’Donnell, J.P.8
Nicolau, D.P.9
-
155
-
-
78650656571
-
Structural basis for effectiveness of siderophore-conjugated monocarbams against clinically relevant strains of Pseudomonas aeruginosa
-
Han S, Zaniewski RP, Marr ES, Lacey BM, Tomaras AP, Evdokimov A, Miller JR, Shanmugasundaram V (2010) Structural basis for effectiveness of siderophore-conjugated monocarbams against clinically relevant strains of Pseudomonas aeruginosa. Proc Natl Acad Sci U S A 107:22002–22007. doi:10.1073/pnas.1013092107
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 22002-22007
-
-
Han, S.1
Zaniewski, R.P.2
Marr, E.S.3
Lacey, B.M.4
Tomaras, A.P.5
Evdokimov, A.6
Miller, J.R.7
Shanmugasundaram, V.8
-
156
-
-
79956107812
-
Preparation, Gram-negative antibacterial activity, and hydrolytic stability of novel siderophore-conjugated monocarbam diols
-
Flanagan ME, Brickner SJ, Lall M, Casavant J, Deschenes L, Finegan SM, George DM, Granskog K, Hardink JR, Huband MD, Hoang T, Lamb L, Marra A, Mitton-Fry M, Mueller JP, Mullins LM, Noe MC, O’Donnell JP, Pattavina D, Penzien JB, Schuff BP, Sun J, Whipple DA, Young J, Gootz TD (2011) Preparation, Gram-negative antibacterial activity, and hydrolytic stability of novel siderophore-conjugated monocarbam diols. ACS Med Chem Lett 2:385–390. doi:10.1021/ml200012f
-
(2011)
ACS Med Chem Lett
, vol.2
, pp. 385-390
-
-
Flanagan, M.E.1
Brickner, S.J.2
Lall, M.3
Casavant, J.4
Deschenes, L.5
Finegan, S.M.6
George, D.M.7
Granskog, K.8
Hardink, J.R.9
Huband, M.D.10
Hoang, T.11
Lamb, L.12
Marra, A.13
Mitton-Fry, M.14
Mueller, J.P.15
Mullins, L.M.16
Noe, M.C.17
O’Donnell, J.P.18
Pattavina, D.19
Penzien, J.B.20
Schuff, B.P.21
Sun, J.22
Whipple, D.A.23
Young, J.24
Gootz, T.D.25
more..
-
157
-
-
84996478385
-
Siderophore cephalosporin cefiderocol utilizes ferric iron transporter systems for antibacterial activity against Pseudomonas aeruginosa
-
Ito A, Nishikawa T, Matsumoto S, Yoshizawa H, Sato T, Nakamura R, Tsuji M, Yamano Y (2016) Siderophore cephalosporin cefiderocol utilizes ferric iron transporter systems for antibacterial activity against Pseudomonas aeruginosa. Antimicrob Agents Chemother 60:7396–7401. doi:10.1128/aac.01405-16
-
(2016)
Antimicrob Agents Chemother
, vol.60
, pp. 7396-7401
-
-
Ito, A.1
Nishikawa, T.2
Matsumoto, S.3
Yoshizawa, H.4
Sato, T.5
Nakamura, R.6
Tsuji, M.7
Yamano, Y.8
-
158
-
-
84960837126
-
In vitro antimicrobial activity of S-649266, a catechol-substituted siderophore cephalosporin, when tested against non-fermenting Gram-negative bacteria
-
Ito A, Kohira N, Bouchillon SK, West J, Rittenhouse S, Sader HS, Rhomberg PR, Jones RN, Yoshizawa H, Nakamura R, Tsuji M, Yamano Y (2016) In vitro antimicrobial activity of S-649266, a catechol-substituted siderophore cephalosporin, when tested against non-fermenting Gram-negative bacteria. J Antimicrob Chemother 71:670–677. doi:10. 1093/jac/dkv402
-
(2016)
J Antimicrob Chemother
, vol.71
, pp. 670-677
-
-
Ito, A.1
Kohira, N.2
Bouchillon, S.K.3
West, J.4
Rittenhouse, S.5
Sader, H.S.6
Rhomberg, P.R.7
Jones, R.N.8
Yoshizawa, H.9
Nakamura, R.10
Tsuji, M.11
Yamano, Y.12
-
159
-
-
84957895337
-
In vitro antimicrobial activity of a siderophore cephalosporin, S-649266, against Enterobacteriaceae clinical isolates, including carbapenem-resistant strains
-
Kohira N, West J, Ito A, Ito-Horiyama T, Nakamura R, Sato T, Rittenhouse S, Tsuji M, Yamano Y (2016) In vitro antimicrobial activity of a siderophore cephalosporin, S-649266, against Enterobacteriaceae clinical isolates, including carbapenem-resistant strains. Antimicrob Agents Chemother 60:729–734. doi:10.1128/aac.01695-15
-
(2016)
Antimicrob Agents Chemother
, vol.60
, pp. 729-734
-
-
Kohira, N.1
West, J.2
Ito, A.3
Ito-Horiyama, T.4
Nakamura, R.5
Sato, T.6
Rittenhouse, S.7
Tsuji, M.8
Yamano, Y.9
-
160
-
-
9744232909
-
Time-related differences in the physical property profiles of oral drugs
-
Leeson PD, Davis AM (2004) Time-related differences in the physical property profiles of oral drugs. J Med Chem 47:6338–6348. https://doi.org/10.1021/jm049717d
-
(2004)
J Med Chem
, vol.47
, pp. 6338-6348
-
-
Leeson, P.D.1
Davis, A.M.2
-
161
-
-
0034088129
-
Antimicrobial effects of novel siderophores linked to β-lactam antibiotics
-
Kline T, Fromhold M, McKennon TE, Cai S, Treiberg J, Ihle N, Sherman D, Schwan W, Hickey MJ, Warrener P, Witte PR, Brody LL, Goltry L, Barker LM, Anderson SU, Tanaka SK, Shawar RM, Nguyen LY, Langhorne M, Bigelow A, Embuscado L, Naeemi E (2000) Antimicrobial effects of novel siderophores linked to β-lactam antibiotics. Bioorg Med Chem 8:73–93. doi:10.1016/S0968-0896(99)00261-8
-
(2000)
Bioorg Med Chem
, vol.8
, pp. 73-93
-
-
Kline, T.1
Fromhold, M.2
McKennon, T.E.3
Cai, S.4
Treiberg, J.5
Ihle, N.6
Sherman, D.7
Schwan, W.8
Hickey, M.J.9
Warrener, P.10
Witte, P.R.11
Brody, L.L.12
Goltry, L.13
Barker, L.M.14
Anderson, S.U.15
Tanaka, S.K.16
Shawar, R.M.17
Nguyen, L.Y.18
Langhorne, M.19
Bigelow, A.20
Embuscado, L.21
Naeemi, E.22
more..
-
162
-
-
84954570572
-
Pharmacodynamic profiling of a siderophore-conjugated monocarbam in Pseudomonas aeruginosa: Assessing the risk for resistance and attenuated efficacy
-
Kim A, Kutschke A, Ehmann DE, Patey SA, Crandon JL, Gorseth E, Miller AA, McLaughlin RE, Blinn CM, Chen A, Nayar AS, Dangel B, Tsai AS, Rooney MT, Murphy-Benenato KE, Eakin AE, Nicolau DP (2015) Pharmacodynamic profiling of a siderophore-conjugated monocarbam in Pseudomonas aeruginosa: assessing the risk for resistance and attenuated efficacy. Antimicrob Agents Chemother 59:7743–7752. doi:10.1128/aac.00831-15
-
(2015)
Antimicrob Agents Chemother
, vol.59
, pp. 7743-7752
-
-
Kim, A.1
Kutschke, A.2
Ehmann, D.E.3
Patey, S.A.4
Crandon, J.L.5
Gorseth, E.6
Miller, A.A.7
McLaughlin, R.E.8
Blinn, C.M.9
Chen, A.10
Nayar, A.S.11
Dangel, B.12
Tsai, A.S.13
Rooney, M.T.14
Murphy-Benenato, K.E.15
Eakin, A.E.16
Nicolau, D.P.17
-
163
-
-
0026535375
-
Iron transport-mediated antibacterial activity of and development of resistance to hydroxamate and catechol siderophore-carbacepholosporin conjugates
-
Minnick AA, McKee JA, Dolence EK, Miller MJ (1992) Iron transport-mediated antibacterial activity of and development of resistance to hydroxamate and catechol siderophore-carbacepholosporin conjugates. Antimicrob Agents Chemother 36:840–850. doi:10.1128/AAC.36.4.840
-
(1992)
Antimicrob Agents Chemother
, vol.36
, pp. 840-850
-
-
Minnick, A.A.1
McKee, J.A.2
Dolence, E.K.3
Miller, M.J.4
-
164
-
-
10344230917
-
Species selectivity of new siderophore-drug conjugates that use specific iron uptake for entry into bacteria
-
Diarra MS, Lavoie MC, Jacques M, Darwish I, Dolence EK, Dolence JA, Ghosh A, Ghosh M, Miller MJ, Malouin F (1996) Species selectivity of new siderophore-drug conjugates that use specific iron uptake for entry into bacteria. Antimicrob Agents Chemother 40:2610–2617
-
(1996)
Antimicrob Agents Chemother
, vol.40
, pp. 2610-2617
-
-
Diarra, M.S.1
Lavoie, M.C.2
Jacques, M.3
Darwish, I.4
Dolence, E.K.5
Dolence, J.A.6
Ghosh, A.7
Ghosh, M.8
Miller, M.J.9
Malouin, F.10
-
165
-
-
0030453553
-
Iron transport-mediated drug delivery using mixed-ligand siderophore-β-lactam conjugates
-
Ghosh A, Ghosh M, Niu C, Malouin F, M€ollmann U, Miller MJ (1996) Iron transport-mediated drug delivery using mixed-ligand siderophore-β-lactam conjugates. Chem Biol 3 (12):1011–1019. doi:10.1016/S1074-5521(96)90167-2
-
(1996)
Chem Biol
, vol.3
, Issue.12
, pp. 1011-1019
-
-
Ghosh, A.1
Ghosh, M.2
Niu, C.3
Malouin, F.4
M€Ollmann, U.5
Miller, M.J.6
-
166
-
-
84878035473
-
Biscatecholate-monohydroxamate mixed ligand siderophore-carbacephalosporin conjugates are selective sideromycin antibiotics that target Acinetobacter baumannii
-
Wencewicz TA, Miller MJ (2013) Biscatecholate-monohydroxamate mixed ligand siderophore-carbacephalosporin conjugates are selective sideromycin antibiotics that target Acinetobacter baumannii. J Med Chem 56:4044–4052. doi:10.1021/jm400265k
-
(2013)
J Med Chem
, vol.56
, pp. 4044-4052
-
-
Wencewicz, T.A.1
Miller, M.J.2
-
167
-
-
84874994725
-
Structure and biosynthesis of fimsbactins A-F, siderophores from Acinetobacter baumannii and Acinetobacter baylyi
-
Proschak A, Lubuta P, Grun P, Lohr F, Wilharm G, De Berardinis V, Bode HB (2013) Structure and biosynthesis of fimsbactins A-F, siderophores from Acinetobacter baumannii and Acinetobacter baylyi. ChemBioChem 14:633–638. doi:10.1002/cbic.201200764
-
(2013)
Chembiochem
, vol.14
, pp. 633-638
-
-
Proschak, A.1
Lubuta, P.2
Grun, P.3
Lohr, F.4
Wilharm, G.5
de Berardinis, V.6
Bode, H.B.7
-
168
-
-
33846208406
-
Synthesis of pyochelin-norfloxacin conjugates
-
Rivault F, Liebert C, Burger A, Hoegy F, Abdallah MA, Schalk IJ, Mislin GL (2007) Synthesis of pyochelin-norfloxacin conjugates. Bioorg Med Chem Lett 17:640–644. doi:10. 1016/j.bmcl.2006.11.005
-
(2007)
Bioorg Med Chem Lett
, vol.17
, pp. 640-644
-
-
Rivault, F.1
Liebert, C.2
Burger, A.3
Hoegy, F.4
Abdallah, M.A.5
Schalk, I.J.6
Mislin, G.L.7
-
169
-
-
84877655609
-
Staphyloferrin A as siderophore-component in fluoroquinolone-based Trojan horse antibiotics
-
Milner SJ, Seve A, Snelling AM, Thomas GH, Kerr KG, Routledge A, Duhme-Klair AK (2013) Staphyloferrin A as siderophore-component in fluoroquinolone-based Trojan horse antibiotics. Org Biomol Chem 11:3461–3468. doi:10.1039/c3ob40162f
-
(2013)
Org Biomol Chem
, vol.11
, pp. 3461-3468
-
-
Milner, S.J.1
Seve, A.2
Snelling, A.M.3
Thomas, G.H.4
Kerr, K.G.5
Routledge, A.6
Duhme-Klair, A.K.7
-
170
-
-
84870882500
-
Synthesis and antibacterial activity of conjugates between norfloxacin and analogues of the siderophore vanchrobactin
-
Souto A, Montaos MA, Balado M, Osorio CR, Rodriguez J, Lemos ML, Jimenez C (2013) Synthesis and antibacterial activity of conjugates between norfloxacin and analogues of the siderophore vanchrobactin. Bioorg Med Chem 21:295–302. doi:10.1016/j.bmc.2012.10.028
-
(2013)
Bioorg Med Chem
, vol.21
, pp. 295-302
-
-
Souto, A.1
Montaos, M.A.2
Balado, M.3
Osorio, C.R.4
Rodriguez, J.5
Lemos, M.L.6
Jimenez, C.7
-
171
-
-
0031750326
-
The synthesis and antibacterial activity of two pyoverdin-ampicillin conjugates, entering Pseudomonas aeruginosa via the pyoverdin-mediated iron uptake pathway
-
Kinzel O, Tappe R, Gerus I, Budzikiewicz H (1998) The synthesis and antibacterial activity of two pyoverdin-ampicillin conjugates, entering Pseudomonas aeruginosa via the pyoverdin-mediated iron uptake pathway. J Antibiot 51:499–507. doi:10.7164/antibiotics. 51.499
-
(1998)
J Antibiot
, vol.51
, pp. 499-507
-
-
Kinzel, O.1
Tappe, R.2
Gerus, I.3
Budzikiewicz, H.4
-
172
-
-
84903954444
-
Enterobactin-mediated delivery of β-lactam antibiotics enhances antibacterial activity against pathogenic Escherichia coli
-
Zheng T, Nolan EM (2014) Enterobactin-mediated delivery of β-lactam antibiotics enhances antibacterial activity against pathogenic Escherichia coli. J Am Chem Soc 136:9677–9691. doi:10.1021/ja503911p
-
(2014)
J am Chem Soc
, vol.136
, pp. 9677-9691
-
-
Zheng, T.1
Nolan, E.M.2
-
173
-
-
84937145609
-
Targeting virulence: salmochelin modification tunes the antibacterial activity spectrum of β-lactams for pathogen-selective killing of Escherichia coli
-
Chairatana P, Zheng T, Nolan EM (2015) Targeting virulence: salmochelin modification tunes the antibacterial activity spectrum of β-lactams for pathogen-selective killing of Escherichia coli. Chem Sci 6:4458–4471. doi:10.1039/C5SC00962F
-
(2015)
Chem Sci
, vol.6
, pp. 4458-4471
-
-
Chairatana, P.1
Zheng, T.2
Nolan, E.M.3
-
174
-
-
84934942717
-
Clostridium difficile drug pipeline: Challenges in discovery and development of new agents
-
Jarrad AM, Karoli T, Blaskovich MAT, Lyras D, Cooper MA (2015) Clostridium difficile drug pipeline: challenges in discovery and development of new agents. J Med Chem 58:5164–5185. doi:10.1021/jm5016846
-
(2015)
J Med Chem
, vol.58
, pp. 5164-5185
-
-
Jarrad, A.M.1
Karoli, T.2
Blaskovich, M.A.T.3
Lyras, D.4
Cooper, M.A.5
-
175
-
-
85021770759
-
Structure-function studies of acinetobactin analogs
-
Shapiro J, Wencewicz TA (2017) Structure-function studies of acinetobactin analogs. Metallomics. doi:10.1039/c7mt00064b
-
(2017)
Metallomics
-
-
Shapiro, J.1
Wencewicz, T.A.2
-
176
-
-
0033049572
-
Synthesis and biological evaluation of a pyoverdin-β-lactam conjugate: A new type of arginine-specific cross-linking in aqueous solution
-
Kinzel O, Budzikiewicz H (1999) Synthesis and biological evaluation of a pyoverdin-β-lactam conjugate: a new type of arginine-specific cross-linking in aqueous solution. J Pept Res 53:618–625. doi:10.1034/j.1399-3011.1999.00053.x
-
(1999)
J Pept Res
, vol.53
, pp. 618-625
-
-
Kinzel, O.1
Budzikiewicz, H.2
-
177
-
-
0035927431
-
Synthesis and activities of pyoverdin-quinolone adducts: A prospective approach to a specific therapy against Pseudomonas aeruginosa
-
Hennard C, Truong QC, Desnottes JF, Paris JM, Moreau NJ, Abdallah MA (2001) Synthesis and activities of pyoverdin-quinolone adducts: a prospective approach to a specific therapy against Pseudomonas aeruginosa. J Med Chem 44:2139–2151. doi:10.1021/jm990508g
-
(2001)
J Med Chem
, vol.44
, pp. 2139-2151
-
-
Hennard, C.1
Truong, Q.C.2
Desnottes, J.F.3
Paris, J.M.4
Moreau, N.J.5
Abdallah, M.A.6
-
178
-
-
85018507420
-
Iron release from the siderophore pyoverdine in Pseudomonas aeruginosa involves three new actors: FpvC, FpvG, and FpvH
-
Epub ahead of print
-
Ganne G, Brillet K, Basta B, Roche B, Hoegy F, Gasser V, Schalk IJ (2017) Iron release from the siderophore pyoverdine in Pseudomonas aeruginosa involves three new actors: FpvC, FpvG, and FpvH. ACS Chem Biol. doi:10.1021/acschembio.6b01077 (Epub ahead of print)
-
(2017)
ACS Chem Biol
-
-
Ganne, G.1
Brillet, K.2
Basta, B.3
Roche, B.4
Hoegy, F.5
Gasser, V.6
Schalk, I.J.7
-
179
-
-
84944150976
-
Evaluation of (Acyloxy)alkyl ester linkers for antibiotic release from siderophore–antibiotic conjugates
-
Zheng T, Nolan EM (2015) Evaluation of (acyloxy)alkyl ester linkers for antibiotic release from siderophore–antibiotic conjugates. Bioorg Med Chem Lett 25:4987–4991. doi:10.1016/j.bmcl.2015.02.034
-
(2015)
Bioorg Med Chem Lett
, vol.25
, pp. 4987-4991
-
-
Zheng, T.1
Nolan, E.M.2
-
180
-
-
84861580404
-
Chemical syntheses and in vitro antibacterial activity of two desferrioxamine B-ciprofloxacin conjugates with potential esterase and phosphatase triggered drug release linkers
-
Ji C, Miller MJ (2012) Chemical syntheses and in vitro antibacterial activity of two desferrioxamine B-ciprofloxacin conjugates with potential esterase and phosphatase triggered drug release linkers. Bioorg Med Chem 20:3828–3836. doi:10.1016/j.bmc.2012.04.034
-
(2012)
Bioorg Med Chem
, vol.20
, pp. 3828-3836
-
-
Ji, C.1
Miller, M.J.2
-
181
-
-
84940002596
-
Siderophore–fluoroquinolone conjugates containing potential reduction-triggered linkers for drug release: Synthesis and antibacterial activity
-
Ji C, Miller MJ (2015) Siderophore–fluoroquinolone conjugates containing potential reduction-triggered linkers for drug release: synthesis and antibacterial activity. Biometals 28:541–551. doi:10.1007/s10534-015-9830-3
-
(2015)
Biometals
, vol.28
, pp. 541-551
-
-
Ji, C.1
Miller, M.J.2
-
182
-
-
9744232909
-
Time-related differences in the physical property profiles of oral drugs
-
Leeson PD, Davis AM (2004) Time-related differences in the physical property profiles of oral drugs. J Med Chem 47:6338–6348. https://doi.org/10.1021/jm049717d
-
(2004)
J Med Chem
, vol.47
, pp. 6338-6348
-
-
Leeson, P.D.1
Davis, A.M.2
-
183
-
-
78649312737
-
Selective capture and identification of pathogenic bacteria using an immobilized siderophore
-
Doorneweerd DD, Henne WA, Reifenberger RG, Low PS (2010) Selective capture and identification of pathogenic bacteria using an immobilized siderophore. Langmuir 26:15424–15429. doi:10.1021/la101962w
-
(2010)
Langmuir
, vol.26
, pp. 15424-15429
-
-
Doorneweerd, D.D.1
Henne, W.A.2
Reifenberger, R.G.3
Low, P.S.4
-
184
-
-
84957566014
-
Determination of bacterial viability by selective capture using surface-bound siderophores
-
Wolfenden M, Sakamuri R, Anderson A, Prasad L, Schmidt J, Mukundan H (2012) Determination of bacterial viability by selective capture using surface-bound siderophores. Adv Biol Chem 2:396–402. doi:10.4236/abc.2012.24049
-
(2012)
Adv Biol Chem
, vol.2
, pp. 396-402
-
-
Wolfenden, M.1
Sakamuri, R.2
Anderson, A.3
Prasad, L.4
Schmidt, J.5
Mukundan, H.6
-
185
-
-
84865484360
-
Siderophore-based detection of Fe(Iii) and microbial pathogens
-
Zheng T, Nolan EM (2012) Siderophore-based detection of Fe(iii) and microbial pathogens. Metallomics 4:866–880. doi:10.1039/C2MT20082A
-
(2012)
Metallomics
, vol.4
, pp. 866-880
-
-
Zheng, T.1
Nolan, E.M.2
-
186
-
-
84957601838
-
Rapid identification of Pseudomonas spp. Via Raman spectroscopy using pyoverdine as capture probe
-
Pahlow S, St€ockel S, Pollok S, Cialla-May D, R€osch P, Weber K, Popp J (2016) Rapid identification of Pseudomonas spp. via Raman spectroscopy using pyoverdine as capture probe. Anal Chem 88:1570–1577. doi:10.1021/acs.analchem.5b02829
-
(2016)
Anal Chem
, vol.88
, pp. 1570-1577
-
-
Pahlow, S.1
St€Ockel, S.2
Pollok, S.3
Cialla-May, D.4
R€Osch, P.5
Weber, K.6
Popp, J.7
-
187
-
-
84984911619
-
Siderophores as molecular tools in medical and environmental applications
-
Kurth C, Kage H, Nett M (2016) Siderophores as molecular tools in medical and environmental applications. Org Biomol Chem 14:8212–8227. doi:10.1039/C6OB01400C
-
(2016)
Org Biomol Chem
, vol.14
, pp. 8212-8227
-
-
Kurth, C.1
Kage, H.2
Nett, M.3
-
188
-
-
84925796249
-
Beyond iron: Non-classical biological functions of bacterial siderophores
-
Johnstone TC, Nolan EM (2015) Beyond iron: non-classical biological functions of bacterial siderophores. Dalton Trans 44:6320–6339. doi:10.1039/c4dt03559c
-
(2015)
Dalton Trans
, vol.44
, pp. 6320-6339
-
-
Johnstone, T.C.1
Nolan, E.M.2
|