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Volumn 133, Issue 10, 2011, Pages 3260-3263
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Maximizing the therapeutic window of an antimicrobial drug by imparting mitochondrial sequestration in human cells
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Author keywords
[No Author keywords available]
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Indexed keywords
ANTI-MICROBIAL AGENT;
ANTIBACTERIAL EFFICACY;
ANTIMICROBIAL DRUG;
CHEMICAL AGENT;
CLINICAL UTILITY;
CROSS-REACTIVITY;
GRAM-POSITIVE ORGANISMS;
HOST ORGANISM;
HUMAN CELLS;
INFECTIOUS DISEASE;
METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS;
NOVEL METHODOLOGY;
PROOF OF PRINCIPLES;
SMALL MOLECULE INHIBITOR;
ENZYME INHIBITION;
MICROORGANISMS;
MITOCHONDRIA;
PEPTIDES;
TOXICITY;
ANTIBIOTIC AGENT;
ANTIMETABOLITE;
METHOTREXATE;
ANTIBACTERIAL ACTIVITY;
ANTIMICROBIAL ACTIVITY;
ARTICLE;
CONJUGATE;
CONTROLLED STUDY;
CYTOTOXICITY;
DRUG DISTRIBUTION;
DRUG EFFICACY;
GRAM POSITIVE BACTERIUM;
HUMAN;
HUMAN CELL;
METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS;
MITOCHONDRION;
NONHUMAN;
PHARMACOLOGICAL PARAMETERS;
THERAPEUTIC WINDOW;
ANTI-BACTERIAL AGENTS;
BIOLOGICAL TRANSPORT;
COMMUNICABLE DISEASES;
ESCHERICHIA COLI;
HELA CELLS;
HUMANS;
METHOTREXATE;
MITOCHONDRIA;
PEPTIDES;
STREPTOCOCCUS PNEUMONIAE;
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EID: 79952578695
PISSN: 00027863
EISSN: 15205126
Source Type: Journal
DOI: 10.1021/ja110246u Document Type: Article |
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Times cited : (50)
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References (12)
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