Design, synthesis and microbiological evaluation of ampicillin-tetramic acid hybrid antibiotics

Journal of Antibiotics

Volumn 70, Issue 1, 2017, Pages 65-72

  Cherian, Philip T ^a   Deshpande, Aditi ^b   Cheramie, Martin N ^a   Bruhn, David F ^a   Hurdle, Julian G ^b   Lee, Richard E ^a  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b TEXAS A AND M HEALTH SCIENCE CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMPICILLIN; ANTIBIOTIC AGENT; BETA LACTAM ANTIBIOTIC; BETA LACTAMASE; CARBENICILLIN; CATECHOL; CLAVULANIC ACID; ENTEROCHELIN; FERRIC ION; IRON; MEMBRANE RECEPTOR; PENICILLIN BINDING PROTEIN; PIPERACILLIN; PYOVERDINE; SIDEROPHORE; TETRAMIC ACID DERIVATIVE; UREIDOPENICILLIN; 2 PYRROLIDONE DERIVATIVE; ANTIINFECTIVE AGENT; BETA LACTAM; TETRAMIC ACID;

ACINETOBACTER BAUMANNII; AGAR DIFFUSION; ANTIMICROBIAL ACTIVITY; ARTICLE; BACILLUS ANTHRACIS; BACILLUS SUBTILIS; BACTERIAL STRAIN; BINDING AFFINITY; BROTH DILUTION; CONTROLLED STUDY; CYTOTOXICITY; DRUG DESIGN; DRUG SCREENING; DRUG SYNTHESIS; ENTEROCOCCUS FAECALIS; ESCHERICHIA COLI; KLEBSIELLA PNEUMONIAE; MEMBRANE PERMEABILITY; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; METHICILLIN SUSCEPTIBLE STAPHYLOCOCCUS AUREUS; MINIMUM INHIBITORY CONCENTRATION; MUELLER HINTON BROTH; NONHUMAN; PRIORITY JOURNAL; PROTEUS MIRABILIS; PSEUDOMONAS AERUGINOSA; STOICHIOMETRY; STREPTOCOCCUS PNEUMONIAE; STREPTOCOCCUS PYOGENES; TAUTOMER; WILD TYPE; ANTIBIOTIC RESISTANCE; DRUG EFFECTS; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; METABOLISM; MICROBIAL SENSITIVITY TEST; SPECIES DIFFERENCE; SYNTHESIS;

AMPICILLIN; ANTI-BACTERIAL AGENTS; BETA-LACTAMASES; BETA-LACTAMS; DRUG DESIGN; DRUG RESISTANCE, BACTERIAL; GRAM-NEGATIVE BACTERIA; GRAM-POSITIVE BACTERIA; MICROBIAL SENSITIVITY TESTS; PYRROLIDINONES; SIDEROPHORES; SPECIES SPECIFICITY;

EID: 85008311832     PISSN: 00218820     EISSN: 18811469     Source Type: Journal    
DOI: 10.1038/ja.2016.52     Document Type: Article

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