Synthesis of pyochelin-norfloxacin conjugates

Bioorganic and Medicinal Chemistry Letters

Volumn 17, Issue 3, 2007, Pages 640-644

  Rivault, Freddy ^a   Liébert, Clémence ^a   Burger, Alain ^a   Hoegy, Françoise ^a   Abdallah, Mohamed A ^a   Schalk, Isabelle J ^a   Mislin, Gaëtan L A ^a  

^a UNIVERSITÉ DE STRASBOURG   (France)

Author keywords

Burkholderia; Cystic fibrosis; Fluoroquinolone; Iron uptake; Pseudomonas; Pyochelin; Siderophore

Indexed keywords

NORFLOXACIN; PYOCHELIN; QUINOLONE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BACTERICIDAL ACTIVITY; BIOLOGICAL ACTIVITY; BURKHOLDERIA; DRUG SYNTHESIS; NONHUMAN; PSEUDOMONAS;

ANTI-BACTERIAL AGENTS; BURKHOLDERIA CEPACIA; IRON CHELATING AGENTS; MAGNETIC RESONANCE SPECTROSCOPY; MICROBIAL SENSITIVITY TESTS; NORFLOXACIN; PHENOLS; PSEUDOMONAS AERUGINOSA; STRUCTURE-ACTIVITY RELATIONSHIP; THIAZOLES;

BURKHOLDERIA; PSEUDOMONAS;

EID: 33846208406     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2006.11.005     Document Type: Article

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24. +).
25. 3, 75 MHz): δ (ppm) = 176.8; 171.5; 171.2; 167.0; 153.4 (d, J = 252 Hz); 153.4; 147.2; 145.7 (d, J = 10 Hz); 137.1; 120.7 (d, J = 7 Hz); 112.6 (d, J = 23 Hz); 108.2; 104.4; 80.9; 80.5; 49.8; 49.6; 43.9; 43.5; 30.0; 29.2; 28.1; 14.5.
26. +).
27. 2: 857.2645. Found 857.2648.
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