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Volumn 14, Issue 4, 2006, Pages 1007-1020
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Structure-activity relationships and enzyme inhibition of pantothenamide-type pantothenate kinase inhibitors
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Author keywords
Coenzyme A; Fatty acid synthase; Pantothenamide; Pantothenate kinase; Structure based drug design
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Indexed keywords
2,4 DIHYDROXY 3,3 DIMETHYL N (2 HEPTYLCARBAMOYLETHYL) BUTYRAMIDE;
2,4 DIHYDROXY 3,3 DIMETHYL N (2 ISOBUTYLCARBAMOYL ETHYL) BUTYRAMIDE;
2,4 DIHYDROXY 3,3 DIMETHYL N (2 PENTYLCARBAMOYLETHYL) BUTYRAMIDE;
2,4 DIHYDROXY 3,3 DIMETHYL N (2 PHENETYLCARBAMOYLETHYL) BUTYRAMIDE;
2,4 DIHYDROXY 3,3 DIMETHYL N (2 PROPYLCARBAMOYL ETHYL) BUTYRAMIDE;
2,4 DIHYDROXY 3,3 DIMETHYL N [2 (1 METHYL 3 PHENYL PROPYLCARBAMOYL) ETHYL] BUTYRAMIDE;
2,4 DIHYDROXY 3,3 DIMETHYL N [2 (2 ETHOXY ETHYLCARBAMOYL) ETHYL] BUTYRAMIDE;
2,4 DIHYDROXY 3,3 DIMETHYL N [2 (2 ETHYLSULFANYL ETHYLCARBAMOYL) ETHYL] BUTYRAMIDE;
2,4 DIHYDROXY 3,3 DIMETHYL N [2 (2 METHYLSULFANYL ETHYLCARBAMOYL) ETHYL] BUTYRAMIDE;
2,4 DIHYDROXY 3,3 DIMETHYL N [2 (2 MORPHOLIN 4 YL ETHYLCARBAMOYL) ETHYL] BUTYRAMIDE;
2,4 DIHYDROXY 3,3 DIMETHYL N [2 (2,6,6 TRIMETHYL BICYCLO[3.1.1]HEPT 3 YLCARBAMOYL) ETHYL] BUTYRAMIDE;
2,4 DIHYDROXY 3,3 DIMETHYL N [2 (3 ETHOXY PROPYLCARBAMOYL) ETHYL] BUTYRAMIDE;
2,4 DIHYDROXY 3,3 DIMETHYL N [2 (3 METHYLSULFANYL PROPYLCARBAMOYL) ETHYL] BUTYRAMIDE;
2,4 DIHYDROXY 3,3 DIMETHYL N [2 (3,4,5 TRIMETHOXY BENZYLCARBAMOYL) ETHYL] BUTYRAMIDE;
2,4 DIHYDROXY 3,3 DIMETHYL N [2 (3,7 DIMETHYL OCTA 2,6 DIENYLCARBAMOYL) ETHYL] BUTYRAMIDE;
2,4 DIHYDROXY 3,3 DIMETHYL N [2 (4 METHOXY BENZYLCARBAMOYL) ETHYL] 3,3 DIMETHYL BUTYRAMIDE;
2,4 DIHYDROXY 3,3 DIMETHYL N [2 [2(3,4 DIMETHOXY PHENYL) ETHYLCARBAMOYL]ETHYL] BUTYRAMIDE;
2,4 DIHYDROXY 3,3 DIMETHYL N [3 (4 BENZYL PIPERAZIN 1 YL) 3 OXO PROPYL] BUTYRAMIDE;
2,4 DIHYDROXY N [2 (2 HYDROXY ETHYLCARBAMOYL) ETHYL] 3,3 DIMETHYL BUTYRAMIDE;
2,4 DIHYDROXY N [2 (2 METHOXY ETHYLCARBAMOYL) ETHYL] 3,3 DIMETHYL BUTYRAMIDE;
2,4 DIHYDROXY N [2 (3 HYDROXY PROPYLCARBAMOYL) ETHYL] 3,3 DIMETHYL BUTYRAMIDE;
2,4 DIHYDROXY N [2 (3 METHOXY PROPYLCARBAMOYL) ETHYL] 3,3 DIMETHYL BUTYRAMIDE;
4 (2 AMINO 4 HYDROXY 3,3 DIMETHYL BUTYRYLAMINO) BUTYRIC ACID;
4 (2,4 DIHYDROXY 3,3 DIMETHYL BUTYRYLAMINO) BUTYRIC ACID;
PANTOTHENATE KINASE;
PHOSPHOTRANSFERASE INHIBITOR;
UNCLASSIFIED DRUG;
ANTIMICROBIAL ACTIVITY;
ARTICLE;
BINDING SITE;
CONTROLLED STUDY;
DRUG EFFECT;
DRUG INHIBITION;
DRUG MECHANISM;
DRUG SCREENING;
DRUG SYNTHESIS;
ENZYME ACTIVITY;
ENZYME INHIBITION;
LIPOPHILICITY;
NONHUMAN;
STEREOSPECIFICITY;
STRUCTURE ACTIVITY RELATION;
BINDING SITES;
ESCHERICHIA COLI;
MICROBIAL SENSITIVITY TESTS;
MODELS, MOLECULAR;
PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR);
PROTEIN KINASE INHIBITORS;
PROTEIN STRUCTURE, TERTIARY;
STAPHYLOCOCCUS AUREUS;
STRUCTURE-ACTIVITY RELATIONSHIP;
EMERICELLA NIDULANS;
ESCHERICHIA COLI;
MURINAE;
STAPHYLOCOCCUS AUREUS;
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EID: 30344458817
PISSN: 09680896
EISSN: None
Source Type: Journal
DOI: 10.1016/j.bmc.2005.09.021 Document Type: Article |
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Times cited : (58)
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References (22)
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