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Volumn 47, Issue 25, 2004, Pages 6338-6348

Time-related differences in the physical property profiles of oral drugs

Author keywords

[No Author keywords available]

Indexed keywords

ANALGESIC AGENT; ANTIALLERGIC AGENT; ANTIARRHYTHMIC AGENT; ANTIASTHMATIC AGENT; ANTICONVULSIVE AGENT; ANTIDIABETIC AGENT; ANTIEMETIC AGENT; ANTIHISTAMINIC AGENT; ANTIHYPERTENSIVE AGENT; ANTIINFECTIVE AGENT; ANTIINFLAMMATORY AGENT; ANTILIPEMIC AGENT; ANTIMIGRAINE AGENT; ANTINEOPLASTIC AGENT; ANTIOBESITY AGENT; ANTIPARKINSON AGENT; ANTIRHEUMATIC AGENT; ANTITHROMBOCYTIC AGENT; ANTITUSSIVE AGENT; ANTIULCER AGENT; ANXIOLYTIC AGENT; CARDIOVASCULAR AGENT; CENTRAL NERVOUS SYSTEM AGENTS; DIURETIC AGENT; IMMUNOSUPPRESSIVE AGENT; MUSCLE RELAXANT AGENT; NEUROLEPTIC AGENT; SPASMOLYTIC AGENT; UNINDEXED DRUG; VASODILATOR AGENT;

EID: 9744232909     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm049717d     Document Type: Article
Times cited : (278)

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    • note
    • From the list in ref 1, there are an additional 8 oral drugs approved for the first time in the U.S. in 2003 that are not included in this study (miglustat, epinastine, tadalafil, gefitinib, rosuvastatin, vardenafil, aprepitant, and atazanavir). The mean (median) physical property values for these 8 drugs show increases in physical properties relative to 1983-2002 oral drugs: Mol Wt 440 (464); cLogP 3.12 (2.85); O + N 7.75 (7) and OH + NH 2.38 (2). Their inclusion in the analysis does not alter the conclusions reached in this paper.
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.