Glycosylation of fluoroquinolones through direct and oxygenated polymethylene linkages as a sugar-mediated active transport system for antimicrobials

Journal of Medicinal Chemistry

Volumn 42, Issue 19, 1999, Pages 3899-3909

  Jung, Michael E ^a   Yang, Eric C ^a   Vu, Binh T ^a   Kiankarimi, Mehrak ^a   Spyrou, Emmanouil ^a   Kaunitz, Jon ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 CYCLOPROPYL 1,4 DIHYDRO 6 FLUORO 7 [4 [3 [(BETA GLUCOPYRANOSYL)OXY]PROPYL]PIPERAZINYL] 4 OXOQUINOLINE 3 CARBOXYLIC ACID; CIPROFLOXACIN; CIPROFLOXACIN DERIVATIVE; QUINOLINE DERIVED ANTIINFECTIVE AGENT; UNCLASSIFIED DRUG;

ACTIVE TRANSPORT; ANTIBACTERIAL ACTIVITY; ARTICLE; DRUG SYNTHESIS; DRUG UPTAKE; GLYCOSYLATION; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ACTIVITY RELATION;

ANTI-INFECTIVE AGENTS; BIOLOGICAL TRANSPORT, ACTIVE; CIPROFLOXACIN; GALACTOSE; GLUCOSE; GLYCOSYLATION; HALF-LIFE; MAGNETIC RESONANCE SPECTROSCOPY; MICROBIAL SENSITIVITY TESTS; PIPERAZINES;

EID: 0033598377     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm990015b     Document Type: Article

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