-
1
-
-
84950992863
-
The role of the 14-3-3 protein family in health, disease, and drug development
-
Aghazadeh, Y., and Papadopoulos, V. (2016). The role of the 14-3-3 protein family in health, disease, and drug development. Drug Discov. Today 21, 278–287. doi: 10.1016/j.drudis.2015.09.012
-
(2016)
Drug Discov. Today
, vol.21
, pp. 278-287
-
-
Aghazadeh, Y.1
Papadopoulos, V.2
-
2
-
-
84960324799
-
Ubiquitin chain diversity at a glance
-
Akutsu, M., Dikic, I., and Bremm, A. (2016). Ubiquitin chain diversity at a glance. J. Cell Sci. 129, 875–880. doi: 10.1242/jcs.183954
-
(2016)
J. Cell Sci.
, vol.129
, pp. 875-880
-
-
Akutsu, M.1
Dikic, I.2
Bremm, A.3
-
3
-
-
0344443774
-
BAG-1–a nucleotide exchange factor of Hsc70 with multiple cellular functions
-
Alberti, S., Esser, C., and Hohfeld, J. (2003). BAG-1–a nucleotide exchange factor of Hsc70 with multiple cellular functions. Cell Stress Chaperones 8, 225–231.
-
(2003)
Cell Stress Chaperones
, vol.8
, pp. 225-231
-
-
Alberti, S.1
Esser, C.2
Hohfeld, J.3
-
4
-
-
85009968750
-
Interference with the HSF1/HSP70/BAG3 pathway primes glioma cells to matrix detachment and BH3 mimetic-induced apoptosis
-
Antonietti, P., Linder, B., Hehlgans, S., Mildenberger, I. C., Burger, M. C., Fulda, S., et al. (2017). Interference with the HSF1/HSP70/BAG3 pathway primes glioma cells to matrix detachment and BH3 mimetic-induced apoptosis. Mol. Cancer Ther. 16, 156–168. doi: 10.1158/1535-7163.MCT-16-0262
-
(2017)
Mol. Cancer Ther.
, vol.16
, pp. 156-168
-
-
Antonietti, P.1
Linder, B.2
Hehlgans, S.3
Mildenberger, I.C.4
Burger, M.C.5
Fulda, S.6
-
5
-
-
81255197001
-
Dilated cardiomyopathy-associated BAG3 mutations impair Z-disc assembly and enhance sensitivity to apoptosis in cardiomyocytes
-
Arimura, T., Ishikawa, T., Nunoda, S., Kawai, S., and Kimura, A. (2011). Dilated cardiomyopathy-associated BAG3 mutations impair Z-disc assembly and enhance sensitivity to apoptosis in cardiomyocytes. Hum. Mutat. 32, 1481–1491. doi: 10.1002/humu.21603
-
(2011)
Hum. Mutat.
, vol.32
, pp. 1481-1491
-
-
Arimura, T.1
Ishikawa, T.2
Nunoda, S.3
Kawai, S.4
Kimura, A.5
-
6
-
-
74549133523
-
Chaperone-assisted selective autophagy is essential for muscle maintenance
-
Arndt, V., Dick, N., Tawo, R., Dreiseidler, M., Wenzel, D., Hesse, M., et al. (2010). Chaperone-assisted selective autophagy is essential for muscle maintenance. Curr. Biol. 20, 143–148. doi: 10.1016/j.cub.2009.11.022
-
(2010)
Curr. Biol.
, vol.20
, pp. 143-148
-
-
Arndt, V.1
Dick, N.2
Tawo, R.3
Dreiseidler, M.4
Wenzel, D.5
Hesse, M.6
-
7
-
-
85009913149
-
The contribution of intrinsically disordered regions to protein function, cellular complexity, and human disease
-
Babu, M. M. (2016). The contribution of intrinsically disordered regions to protein function, cellular complexity, and human disease. Biochem. Soc. Trans. 44, 1185–1200. doi: 10.1042/BST20160172
-
(2016)
Biochem. Soc. Trans.
, vol.44
, pp. 1185-1200
-
-
Babu, M.M.1
-
8
-
-
79959939343
-
BAG3 and friends: Co-chaperones in selective autophagy during aging and disease
-
Behl, C. (2011). BAG3 and friends: co-chaperones in selective autophagy during aging and disease. Autophagy 7, 795–798. doi: 10.4161/auto.7.7.15844
-
(2011)
Autophagy
, vol.7
, pp. 795-798
-
-
Behl, C.1
-
9
-
-
84965077472
-
Breaking BAG: The co-chaperone BAG3 in health and disease
-
Behl, C. (2016). Breaking BAG: the co-chaperone BAG3 in health and disease. Trends Pharmacol. Sci. 37, 672–688. doi: 10.1016/j.tips.2016.04.007
-
(2016)
Trends Pharmacol. Sci.
, vol.37
, pp. 672-688
-
-
Behl, C.1
-
10
-
-
35548990261
-
Transcriptional profiling of genes that are regulated by the endoplasmic reticulum-bound transcription factor AIbZIP/CREB3L4 in prostate cells
-
Ben Aicha, S., Lessard, J., Pelletier, M., Fournier, A., Calvo, E., and Labrie, C. (2007). Transcriptional profiling of genes that are regulated by the endoplasmic reticulum-bound transcription factor AIbZIP/CREB3L4 in prostate cells. Physiol. Genom. 31, 295–305. doi: 10.1152/physiolgenomics.00097.2007
-
(2007)
Physiol. Genom.
, vol.31
, pp. 295-305
-
-
Ben Aicha, S.1
Lessard, J.2
Pelletier, M.3
Fournier, A.4
Calvo, E.5
Labrie, C.6
-
11
-
-
84884520490
-
BH3 mimetics: Status of the field and new developments
-
Billard, C. (2013). BH3 mimetics: status of the field and new developments. Mol. Cancer Ther. 12, 1691–1700. doi: 10.1158/1535-7163.MCT-13-0058
-
(2013)
Mol. Cancer Ther.
, vol.12
, pp. 1691-1700
-
-
Billard, C.1
-
12
-
-
84864486839
-
The family of mammalian small heat shock proteins (HSPBs): Implications in protein deposit diseases and motor neuropathies
-
Boncoraglio, A., Minoia, M., and Carra, S. (2012). The family of mammalian small heat shock proteins (HSPBs): implications in protein deposit diseases and motor neuropathies. Int. J. Biochem. Cell Biol. 44, 1657–1669. doi: 10.1016/j.biocel.2012.03.011
-
(2012)
Int. J. Biochem. Cell Biol.
, vol.44
, pp. 1657-1669
-
-
Boncoraglio, A.1
Minoia, M.2
Carra, S.3
-
13
-
-
10744228410
-
BAG3 protein regulates stress-induced apoptosis in normal and neoplastic leukocytes
-
Bonelli, P., Petrella, A., Rosati, A., Romano, M. F., Lerose, R., Pagliuca, M. G., et al. (2004). BAG3 protein regulates stress-induced apoptosis in normal and neoplastic leukocytes. Leukemia 18, 358–360. doi: 10.1038/sj.leu.2403219
-
(2004)
Leukemia
, vol.18
, pp. 358-360
-
-
Bonelli, P.1
Petrella, A.2
Rosati, A.3
Romano, M.F.4
Lerose, R.5
Pagliuca, M.G.6
-
14
-
-
84880376355
-
Emerging regulation and functions of autophagy
-
Boya, P., Reggiori, F., and Codogno, P. (2013). Emerging regulation and functions of autophagy. Nat. Cell Biol. 15, 713–720. doi: 10.1038/ncb2788
-
(2013)
Nat. Cell Biol.
, vol.15
, pp. 713-720
-
-
Boya, P.1
Reggiori, F.2
Codogno, P.3
-
15
-
-
85021327461
-
The nucleotide exchange factors of Hsp70 molecular chaperones. Front. Mol
-
Bracher, A., and Verghese, J. (2015). The nucleotide exchange factors of Hsp70 molecular chaperones. Front. Mol. Biosci. 2:10. doi: 10.3389/fmolb.2015.00010
-
(2015)
Biosci
, vol.2
, pp. 10
-
-
Bracher, A.1
Verghese, J.2
-
16
-
-
84899116355
-
BAG3 mRNA is present in synaptosomal polysomes of rat brain
-
Bruno, A. P., Cefaliello, C., D’Auria, R., Crispino, M., Rosati, A., Giuditta, A., et al. (2014). BAG3 mRNA is present in synaptosomal polysomes of rat brain. Cell Cycle 13:1357. doi: 10.4161/cc.28655
-
(2014)
Cell Cycle
, vol.13
, pp. 1357
-
-
Bruno, A.P.1
Cefaliello, C.2
D’Auria, R.3
Crispino, M.4
Rosati, A.5
Giuditta, A.6
-
17
-
-
53649105867
-
Identification of a synaptosome-associated form of BAG3 protein
-
Bruno, A. P., Festa, M., Dal Piaz, F., Rosati, A., Turco, M. C., Giuditta, A., et al. (2008). Identification of a synaptosome-associated form of BAG3 protein. Cell Cycle 7, 3104–3105. doi: 10.4161/cc.7.19.6774
-
(2008)
Cell Cycle
, vol.7
, pp. 3104-3105
-
-
Bruno, A.P.1
Festa, M.2
Dal Piaz, F.3
Rosati, A.4
Turco, M.C.5
Giuditta, A.6
-
18
-
-
33646127577
-
Molecular chaperones and protein quality control
-
Bukau, B., Weissman, J., and Horwich, A. (2006). Molecular chaperones and protein quality control. Cell 125, 443–451. doi: 10.1016/j.cell.2006.04.014
-
(2006)
Cell
, vol.125
, pp. 443-451
-
-
Bukau, B.1
Weissman, J.2
Horwich, A.3
-
19
-
-
84921396314
-
Membrane dynamics in autophagosome biogenesis
-
Carlsson, S. R., and Simonsen, A. (2015). Membrane dynamics in autophagosome biogenesis. J. Cell Sci. 128, 193–205. doi: 10.1242/jcs.141036
-
(2015)
J. Cell Sci.
, vol.128
, pp. 193-205
-
-
Carlsson, S.R.1
Simonsen, A.2
-
20
-
-
38349105324
-
HspB8 chaperone activity toward poly(Q)-containing proteins depends on its association with Bag3, a stimulator of macroautophagy
-
Carra, S., Seguin, S. J., Lambert, H., and Landry, J. (2008a). HspB8 chaperone activity toward poly(Q)-containing proteins depends on its association with Bag3, a stimulator of macroautophagy. J. Biol. Chem. 283, 1437–1444. doi: 10.1074/jbc.M706304200
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 1437-1444
-
-
Carra, S.1
Seguin, S.J.2
Lambert, H.3
Landry, J.4
-
21
-
-
38949184241
-
HspB8 and Bag3: A new chaperone complex targeting misfolded proteins to macroautophagy
-
Carra, S., Seguin, S. J., and Landry, J. (2008b). HspB8 and Bag3: a new chaperone complex targeting misfolded proteins to macroautophagy. Autophagy 4, 237–239.
-
(2008)
Autophagy
, vol.4
, pp. 237-239
-
-
Carra, S.1
Seguin, S.J.2
Landry, J.3
-
22
-
-
21244489544
-
HspB8, a small heat shock protein mutated in human neuromuscular disorders, has in vivo chaperone activity in cultured cells
-
Carra, S., Sivilotti, M., Chavez Zobel, A. T., Lambert, H., and Landry, J. (2005). HspB8, a small heat shock protein mutated in human neuromuscular disorders, has in vivo chaperone activity in cultured cells. Hum. Mol. Genet. 14, 1659–1669. doi: 10.1093/hmg/ddi174
-
(2005)
Hum. Mol. Genet.
, vol.14
, pp. 1659-1669
-
-
Carra, S.1
Sivilotti, M.2
Chavez Zobel, A.T.3
Lambert, H.4
Landry, J.5
-
23
-
-
77954589714
-
WT1 protein is a transcriptional activator of the antiapoptotic bag3 gene
-
Cesaro, E., Montano, G., Rosati, A., Crescitelli, R., Izzo, P., Turco, M. C., et al. (2010). WT1 protein is a transcriptional activator of the antiapoptotic bag3 gene. Leukemia 24, 1204–1206. doi: 10.1038/leu.2010.68
-
(2010)
Leukemia
, vol.24
, pp. 1204-1206
-
-
Cesaro, E.1
Montano, G.2
Rosati, A.3
Crescitelli, R.4
Izzo, P.5
Turco, M.C.6
-
24
-
-
84919846033
-
Nonsense mutations in BAG3 are associated with early-onset dilated cardiomyopathy in French Canadians
-
Chami, N., Tadros, R., Lemarbre, F., Lo, K. S., Beaudoin, M., Robb, L., et al. (2014). Nonsense mutations in BAG3 are associated with early-onset dilated cardiomyopathy in French Canadians. Can. J. Cardiol. 30, 1655–1661. doi: 10.1016/j.cjca.2014.09.030
-
(2014)
Can. J. Cardiol.
, vol.30
, pp. 1655-1661
-
-
Chami, N.1
Tadros, R.2
Lemarbre, F.3
Lo, K.S.4
Beaudoin, M.5
Robb, L.6
-
25
-
-
0024514688
-
A multiubiquitin chain is confined to specific lysine in a targeted short-lived protein
-
Chau, V., Tobias, J. W., Bachmair, A., Marriott, D., Ecker, D. J., Gonda, D. K., et al. (1989). A multiubiquitin chain is confined to specific lysine in a targeted short-lived protein. Science 243, 1576–1583.
-
(1989)
Science
, vol.243
, pp. 1576-1583
-
-
Chau, V.1
Tobias, J.W.2
Bachmair, A.3
Marriott, D.4
Ecker, D.J.5
Gonda, D.K.6
-
26
-
-
84885154570
-
Bcl2-associated athanogene 3 interactome analysis reveals a new role in modulating proteasome activity
-
Chen, Y., Yang, L. N., Cheng, L., Tu, S., Guo, S. J., Le, H. Y., et al. (2013). Bcl2-associated athanogene 3 interactome analysis reveals a new role in modulating proteasome activity. Mol. Cell. Proteomics 12, 2804–2819. doi: 10.1074/mcp. M112.025882
-
(2013)
Mol. Cell. Proteomics
, vol.12
, pp. 2804-2819
-
-
Chen, Y.1
Yang, L.N.2
Cheng, L.3
Tu, S.4
Guo, S.J.5
Le, H.Y.6
-
27
-
-
0025644201
-
A 25-kilodalton ubiquitin carrier protein (E2) catalyzes multi-ubiquitin chain synthesis via lysine 48 of ubiquitin
-
Chen, Z., and Pickart, C. M. (1990). A 25-kilodalton ubiquitin carrier protein (E2) catalyzes multi-ubiquitin chain synthesis via lysine 48 of ubiquitin. J. Biol. Chem. 265, 21835–21842.
-
(1990)
J. Biol. Chem
, vol.265
, pp. 21835-21842
-
-
Chen, Z.1
Pickart, C.M.2
-
28
-
-
59649086030
-
Nonproteolytic functions of ubiquitin in cell signaling
-
Chen, Z. J., and Sun, L. J. (2009). Nonproteolytic functions of ubiquitin in cell signaling. Mol. Cell. 33, 275–286. doi: 10.1016/j.molcel.2009.01.014
-
(2009)
Mol. Cell.
, vol.33
, pp. 275-286
-
-
Chen, Z.J.1
Sun, L.J.2
-
29
-
-
84907069899
-
The anti-apoptotic BAG3 protein is expressed in lung carcinomas and regulates small cell lung carcinoma (SCLC) tumor growth
-
Chiappetta, G., Basile, A., Barbieri, A., Falco, A., Rosati, A., Festa, M., et al. (2014). The anti-apoptotic BAG3 protein is expressed in lung carcinomas and regulates small cell lung carcinoma (SCLC) tumor growth. Oncotarget 5, 6846–6853. doi: 10.18632/oncotarget.2261
-
(2014)
Oncotarget
, vol.5
, pp. 6846-6853
-
-
Chiappetta, G.1
Basile, A.2
Barbieri, A.3
Falco, A.4
Rosati, A.5
Festa, M.6
-
30
-
-
84877628647
-
Autophagy in human health and disease
-
Choi, A. M., Ryter, S. W., and Levine, B. (2013). Autophagy in human health and disease. N. Engl. J. Med. 368, 1845–1846. doi: 10.1056/NEJMc1303158
-
(2013)
N. Engl. J. Med.
, vol.368
, pp. 1845-1846
-
-
Choi, A.M.1
Ryter, S.W.2
Levine, B.3
-
31
-
-
84989284335
-
Degradation of misfolded proteins in neurodegenerative diseases: Therapeutic targets and strategies
-
Ciechanover, A., and Kwon, Y. T. (2015). Degradation of misfolded proteins in neurodegenerative diseases: therapeutic targets and strategies. Exp. Mol. Med. 47:e147. doi: 10.1038/emm.2014.117
-
(2015)
Exp. Mol. Med.
, vol.47
-
-
Ciechanover, A.1
Kwon, Y.T.2
-
32
-
-
84907055560
-
Hsp70-Bag3 interactions regulate cancer-related signaling networks
-
Colvin, T. A., Gabai, V. L., Gong, J., Calderwood, S. K., Li, H., Gummuluru, S., et al. (2014). Hsp70-Bag3 interactions regulate cancer-related signaling networks. Cancer Res. 74, 4731–4740. doi: 10.1158/0008-5472.CAN-14-0747
-
(2014)
Cancer Res
, vol.74
, pp. 4731-4740
-
-
Colvin, T.A.1
Gabai, V.L.2
Gong, J.3
Calderwood, S.K.4
Li, H.5
Gummuluru, S.6
-
33
-
-
84888404509
-
Differential autophagy power in the spinal cord and muscle of transgenic ALS mice. Front
-
Crippa, V., Boncoraglio, A., Galbiati, M., Aggarwal, T., Rusmini, P., Giorgetti, E., et al. (2013). Differential autophagy power in the spinal cord and muscle of transgenic ALS mice. Front. Cell Neurosci. 7:234. doi: 10.3389/fncel.2013.00234
-
(2013)
Cell Neurosci
, vol.7
, pp. 234
-
-
Crippa, V.1
Boncoraglio, A.2
Galbiati, M.3
Aggarwal, T.4
Rusmini, P.5
Giorgetti, E.6
-
34
-
-
77957665681
-
A role of small heat shock protein B8 (HspB8) in the autophagic removal of misfolded proteins responsible for neurodegenerative diseases
-
Crippa, V., Carra, S., Rusmini, P., Sau, D., Bolzoni, E., Bendotti, C., et al. (2010a). A role of small heat shock protein B8 (HspB8) in the autophagic removal of misfolded proteins responsible for neurodegenerative diseases. Autophagy 6, 958–960. doi: 10.4161/auto.6.7.13042
-
(2010)
Autophagy
, vol.6
, pp. 958-960
-
-
Crippa, V.1
Carra, S.2
Rusmini, P.3
Sau, D.4
Bolzoni, E.5
Bendotti, C.6
-
35
-
-
77955365630
-
The small heat shock protein B8 (HspB8) promotes autophagic removal of misfolded proteins involved in amyotrophic lateral sclerosis (ALS)
-
Crippa, V., Sau, D., Rusmini, P., Boncoraglio, A., Onesto, E., Bolzoni, E., et al. (2010b). The small heat shock protein B8 (HspB8) promotes autophagic removal of misfolded proteins involved in amyotrophic lateral sclerosis (ALS). Hum. Mol. Genet. 19, 3440–3456. doi: 10.1093/hmg/ddq257
-
(2010)
Hum. Mol. Genet.
, vol.19
, pp. 3440-3456
-
-
Crippa, V.1
Sau, D.2
Rusmini, P.3
Boncoraglio, A.4
Onesto, E.5
Bolzoni, E.6
-
36
-
-
84925944153
-
BAG3 protein in advanced-stage heart failure
-
De Marco, M., D’Auria, R., Rosati, A., Vitulano, G., Gigantino, A., Citro, R., et al. (2014). BAG3 protein in advanced-stage heart failure. JACC Heart Fail 2, 673–675. doi: 10.1016/j.jchf.2014.05.012
-
(2014)
JACC Heart Fail
, vol.2
, pp. 673-675
-
-
De Marco, M.1
D’Auria, R.2
Rosati, A.3
Vitulano, G.4
Gigantino, A.5
Citro, R.6
-
37
-
-
84875997204
-
Detection of soluble BAG3 and anti-BAG3 antibodies in patients with chronic heart failure
-
De Marco, M., Falco, A., Basile, A., Rosati, A., Festa, M., d’Avenia, M., et al. (2013). Detection of soluble BAG3 and anti-BAG3 antibodies in patients with chronic heart failure. Cell Death Dis. 4:e495. doi: 10.1038/cddis.2013.8
-
(2013)
Cell Death Dis
, vol.4
-
-
De Marco, M.1
Falco, A.2
Basile, A.3
Rosati, A.4
Festa, M.5
D’Avenia, M.6
-
38
-
-
84952874791
-
DNAJs: More than substrate delivery to HSPA. Front. Mol
-
Dekker, S. L., Kampinga, H. H., and Bergink, S. (2015). DNAJs: more than substrate delivery to HSPA. Front. Mol. Biosci. 2:35. doi: 10.3389/fmolb.2015.00035
-
(2015)
Biosci
, vol.2
, pp. 35
-
-
Dekker, S.L.1
Kampinga, H.H.2
Bergink, S.3
-
39
-
-
0035899897
-
Cooperation of a ubiquitin domain protein and an E3 ubiquitin ligase during chaperone/proteasome coupling
-
Demand, J., Alberti, S., Patterson, C., and Hohfeld, J. (2001). Cooperation of a ubiquitin domain protein and an E3 ubiquitin ligase during chaperone/proteasome coupling. Curr. Biol. 11, 1569–1577.
-
(2001)
Curr. Biol.
, vol.11
, pp. 1569-1577
-
-
Demand, J.1
Alberti, S.2
Patterson, C.3
Hohfeld, J.4
-
40
-
-
0034644474
-
Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain
-
Deng, L., Wang, C., Spencer, E., Yang, L., Braun, A., You, J., et al. (2000). Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain. Cell 103, 351–361.
-
(2000)
Cell
, vol.103
, pp. 351-361
-
-
Deng, L.1
Wang, C.2
Spencer, E.3
Yang, L.4
Braun, A.5
You, J.6
-
41
-
-
49449085504
-
A quantitative atlas of mitotic phosphorylation
-
Dephoure, N., Zhou, C., Villen, J., Beausoleil, S. A., Bakalarski, C. E., Elledge, S. J., et al. (2008). A quantitative atlas of mitotic phosphorylation. Proc. Natl. Acad. Sci. U.S.A. 105, 10762–10767. doi: 10.1073/pnas.0805139105
-
(2008)
Proc. Natl. Acad. Sci. U.S.A.
, vol.105
, pp. 10762-10767
-
-
Dephoure, N.1
Zhou, C.2
Villen, J.3
Beausoleil, S.A.4
Bakalarski, C.E.5
Elledge, S.J.6
-
42
-
-
0034618385
-
CAIR-1/BAG-3 forms an EGF-regulated ternary complex with phospholipase C-gamma and Hsp70/Hsc70
-
Doong, H., Price, J., Kim, Y. S., Gasbarre, C., Probst, J., Liotta, L. A., et al. (2000). CAIR-1/BAG-3 forms an EGF-regulated ternary complex with phospholipase C-gamma and Hsp70/Hsc70. Oncogene 19, 4385–4395. doi: 10.1038/sj.onc.1203797
-
(2000)
Oncogene
, vol.19
, pp. 4385-4395
-
-
Doong, H.1
Price, J.2
Kim, Y.S.3
Gasbarre, C.4
Probst, J.5
Liotta, L.A.6
-
43
-
-
0042208135
-
CAIR-1/BAG-3 abrogates heat shock protein-70 chaperone complex-mediated protein degradation: Accumulation of poly-ubiquitinated Hsp90 client proteins
-
Doong, H., Rizzo, K., Fang, S., Kulpa, V., Weissman, A. M., and Kohn, E. C. (2003). CAIR-1/BAG-3 abrogates heat shock protein-70 chaperone complex-mediated protein degradation: accumulation of poly-ubiquitinated Hsp90 client proteins. J. Biol. Chem. 278, 28490–28500. doi: 10.1074/jbc.M209682200
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 28490-28500
-
-
Doong, H.1
Rizzo, K.2
Fang, S.3
Kulpa, V.4
Weissman, A.M.5
Kohn, E.C.6
-
44
-
-
0037114358
-
What’s in the ’BAG’?–A functional domain analysis of the BAG-family proteins
-
Doong, H., Vrailas, A., and Kohn, E. C. (2002). What’s in the ’BAG’?–A functional domain analysis of the BAG-family proteins. Cancer Lett. 188, 25–32.
-
(2002)
Cancer Lett
, vol.188
, pp. 25-32
-
-
Doong, H.1
Vrailas, A.2
Kohn, E.C.3
-
45
-
-
84946475663
-
Targeting protein aggregation for the treatment of degenerative diseases
-
Eisele, Y. S., Monteiro, C., Fearns, C., Encalada, S. E., Wiseman, R. L., Powers, E. T., et al. (2015). Targeting protein aggregation for the treatment of degenerative diseases. Nat. Rev. Drug Discov. 14, 759–780. doi: 10.1038/nrd4593
-
(2015)
Nat. Rev. Drug Discov.
, vol.14
, pp. 759-780
-
-
Eisele, Y.S.1
Monteiro, C.2
Fearns, C.3
Encalada, S.E.4
Wiseman, R.L.5
Powers, E.T.6
-
46
-
-
84926132727
-
Versatile roles of k63-linked ubiquitin chains in trafficking
-
Erpapazoglou, Z., Walker, O., and Haguenauer-Tsapis, R. (2014). Versatile roles of k63-linked ubiquitin chains in trafficking. Cells 3, 1027–1088. doi: 10.3390/cells3041027
-
(2014)
Cells
, vol.3
, pp. 1027-1088
-
-
Erpapazoglou, Z.1
Walker, O.2
Haguenauer-Tsapis, R.3
-
47
-
-
84992560024
-
BAG3 protein is over-expressed in endometrioid endometrial adenocarcinomas
-
Esposito, V., Baldi, C., Zeppa, P., Festa, M., Guerriero, L., d’Avenia, M., et al. (2017). BAG3 protein is over-expressed in endometrioid endometrial adenocarcinomas. J. Cell. Physiol. 232, 309–311. doi: 10.1002/jcp.25489
-
(2017)
J. Cell. Physiol.
, vol.232
, pp. 309-311
-
-
Esposito, V.1
Baldi, C.2
Zeppa, P.3
Festa, M.4
Guerriero, L.5
D’Avenia, M.6
-
48
-
-
84880222772
-
BAG3 is a novel serum biomarker for pancreatic adenocarcinomas
-
Falco, A., Rosati, A., Festa, M., Basile, A., De Marco, M., d’Avenia, M., et al. (2013). BAG3 is a novel serum biomarker for pancreatic adenocarcinomas. Am. J. Gastroenterol. 108, 1178–1180. doi: 10.1038/ajg.2013.128
-
(2013)
Am. J. Gastroenterol.
, vol.108
, pp. 1178-1180
-
-
Falco, A.1
Rosati, A.2
Festa, M.3
Basile, A.4
De Marco, M.5
D’Avenia, M.6
-
49
-
-
84904909098
-
Decreased levels of BAG3 in a family with a rare variant and in idiopathic dilated cardiomyopathy
-
Feldman, A. M., Begay, R. L., Knezevic, T., Myers, V. D., Slavov, D. B., Zhu, W., et al. (2014). Decreased levels of BAG3 in a family with a rare variant and in idiopathic dilated cardiomyopathy. J. Cell. Physiol. 229, 1697–1702. doi: 10.1002/jcp.24615
-
(2014)
J. Cell. Physiol.
, vol.229
, pp. 1697-1702
-
-
Feldman, A.M.1
Begay, R.L.2
Knezevic, T.3
Myers, V.D.4
Slavov, D.B.5
Zhu, W.6
-
50
-
-
84961326093
-
BAG3 regulates contractility and Ca(2+) homeostasis in adult mouse ventricular myocytes
-
Feldman, A. M., Gordon, J., Wang, J., Song, J., Zhang, X. Q., Myers, V. D., et al. (2016). BAG3 regulates contractility and Ca(2+) homeostasis in adult mouse ventricular myocytes. J. Mol. Cell Cardiol. 92, 10–20. doi: 10.1016/j.yjmcc.2016.01.015
-
(2016)
J. Mol. Cell Cardiol.
, vol.92
, pp. 10-20
-
-
Feldman, A.M.1
Gordon, J.2
Wang, J.3
Song, J.4
Zhang, X.Q.5
Myers, V.D.6
-
51
-
-
84954310032
-
Estrogen receptor alpha regulates non-canonical autophagy that provides stress resistance to neuroblastoma and breast cancer cells and involves BAG3 function
-
Felzen, V., Hiebel, C., Koziollek-Drechsler, I., Reissig, S., Wolfrum, U., Kogel, D., et al. (2015). Estrogen receptor alpha regulates non-canonical autophagy that provides stress resistance to neuroblastoma and breast cancer cells and involves BAG3 function. Cell Death Dis. 6:e1812. doi: 10.1038/cddis.2015.181
-
(2015)
Cell Death Dis
, vol.6
-
-
Felzen, V.1
Hiebel, C.2
Koziollek-Drechsler, I.3
Reissig, S.4
Wolfrum, U.5
Kogel, D.6
-
52
-
-
84891747382
-
The machinery of macroautophagy
-
Feng, Y., He, D., Yao, Z., and Klionsky, D. J. (2014). The machinery of macroautophagy. Cell Res. 24, 24–41. doi: 10.1038/cr.2013.168
-
(2014)
Cell Res
, vol.24
, pp. 24-41
-
-
Feng, Y.1
He, D.2
Yao, Z.3
Klionsky, D.J.4
-
53
-
-
65649115267
-
Recognition and processing of ubiquitin-protein conjugates by the proteasome
-
Finley, D. (2009). Recognition and processing of ubiquitin-protein conjugates by the proteasome. Annu. Rev. Biochem. 78, 477–513. doi: 10.1146/annurev.biochem.78.081507.101607
-
(2009)
Annu. Rev. Biochem.
, vol.78
, pp. 477-513
-
-
Finley, D.1
-
54
-
-
84867176120
-
The ubiquitin-proteasome system of Saccharomyces cerevisiae
-
Finley, D., Ulrich, H. D., Sommer, T., and Kaiser, P. (2012). The ubiquitin-proteasome system of Saccharomyces cerevisiae. Genetics 192, 319–360. doi: 10.1534/genetics.112.140467
-
(2012)
Genetics
, vol.192
, pp. 319-360
-
-
Finley, D.1
Ulrich, H.D.2
Sommer, T.3
Kaiser, P.4
-
55
-
-
84903865896
-
The BAG3 gene variants in Polish patients with dilated cardiomyopathy: Four novel mutations and a genotype-phenotype correlation
-
Franaszczyk, M., Bilinska, Z. T., Sobieszczanska-Malek, M., Michalak, E., Sleszycka, J., Sioma, A., et al. (2014). The BAG3 gene variants in Polish patients with dilated cardiomyopathy: four novel mutations and a genotype-phenotype correlation. J. Transl. Med. 12:192. doi: 10.1186/1479-5876-12-192
-
(2014)
J. Transl. Med.
, vol.12
, pp. 192
-
-
Franaszczyk, M.1
Bilinska, Z.T.2
Sobieszczanska-Malek, M.3
Michalak, E.4
Sleszycka, J.5
Sioma, A.6
-
56
-
-
42949179530
-
Bag3 gene expression is regulated by heat shock factor 1
-
Franceschelli, S., Rosati, A., Lerose, R., De Nicola, S., Turco, M. C., and Pascale, M. (2008). Bag3 gene expression is regulated by heat shock factor 1. J. Cell. Physiol. 215, 575–577. doi: 10.1002/jcp.21397
-
(2008)
J. Cell. Physiol.
, vol.215
, pp. 575-577
-
-
Franceschelli, S.1
Rosati, A.2
Lerose, R.3
De Nicola, S.4
Turco, M.C.5
Pascale, M.6
-
57
-
-
72449141635
-
Identification of the key structural motifs involved in HspB8/HspB6-Bag3 interaction
-
Fuchs, M., Poirier, D. J., Seguin, S. J., Lambert, H., Carra, S., Charette, S. J., et al. (2009). Identification of the key structural motifs involved in HspB8/HspB6-Bag3 interaction. Biochem. J. 425, 245–255. doi: 10.1042/BJ20090907
-
(2009)
Biochem. J
, vol.425
, pp. 245-255
-
-
Fuchs, M.1
Poirier, D.J.2
Seguin, S.J.3
Lambert, H.4
Carra, S.5
Charette, S.J.6
-
58
-
-
84655163784
-
Emerging roles of molecular chaperones and co-chaperones in selective autophagy: Focus on BAG proteins
-
Gamerdinger, M., Carra, S., and Behl, C. (2011a). Emerging roles of molecular chaperones and co-chaperones in selective autophagy: focus on BAG proteins. J. Mol. Med. (Berl.) 89, 1175–1182. doi: 10.1007/s00109-011-0795-6
-
(2011)
J. Mol. Med. (Berl.)
, vol.89
, pp. 1175-1182
-
-
Gamerdinger, M.1
Carra, S.2
Behl, C.3
-
59
-
-
65449117176
-
Protein quality control during aging involves recruitment of the macroautophagy pathway by BAG3
-
Gamerdinger, M., Hajieva, P., Kaya, A. M., Wolfrum, U., Hartl, F. U., and Behl, C. (2009). Protein quality control during aging involves recruitment of the macroautophagy pathway by BAG3. EMBO J. 28, 889–901. doi: 10.1038/emboj.2009.29
-
(2009)
EMBO J
, vol.28
, pp. 889-901
-
-
Gamerdinger, M.1
Hajieva, P.2
Kaya, A.M.3
Wolfrum, U.4
Hartl, F.U.5
Behl, C.6
-
60
-
-
79551609332
-
BAG3 mediates chaperone-based aggresome-targeting and selective autophagy of misfolded proteins
-
Gamerdinger, M., Kaya, A. M., Wolfrum, U., Clement, A. M., and Behl, C. (2011b). BAG3 mediates chaperone-based aggresome-targeting and selective autophagy of misfolded proteins. EMBO Rep. 12, 149–156. doi: 10.1038/embor.2010.203
-
(2011)
EMBO Rep
, vol.12
, pp. 149-156
-
-
Gamerdinger, M.1
Kaya, A.M.2
Wolfrum, U.3
Clement, A.M.4
Behl, C.5
-
61
-
-
84925949985
-
Analysis of BAG3 plasma concentrations in patients with acutely decompensated heart failure
-
Gandhi, P. U., Gaggin, H. K., Belcher, A. M., Harisiades, J. E., Basile, A., Falco, A., et al. (2015). Analysis of BAG3 plasma concentrations in patients with acutely decompensated heart failure. Clin. Chim. Acta 445, 73–78. doi: 10.1016/j.cca.2015.02.048
-
(2015)
Clin. Chim. Acta
, vol.445
, pp. 73-78
-
-
Gandhi, P.U.1
Gaggin, H.K.2
Belcher, A.M.3
Harisiades, J.E.4
Basile, A.5
Falco, A.6
-
62
-
-
0344466781
-
Characterization and dynamics of aggresome formation by a cytosolic GFP-chimera
-
Garcia-Mata, R., Bebok, Z., Sorscher, E. J., and Sztul, E. S. (1999). Characterization and dynamics of aggresome formation by a cytosolic GFP-chimera. J. Cell Biol. 146, 1239–1254.
-
(1999)
J. Cell Biol.
, vol.146
, pp. 1239-1254
-
-
Garcia-Mata, R.1
Bebok, Z.2
Sorscher, E.J.3
Sztul, E.S.4
-
63
-
-
77958554334
-
Quantitative phosphoproteomics of proteasome inhibition in multiple myeloma cells
-
Ge, F., Xiao, C. L., Bi, L. J., Tao, S. C., Xiong, S., Yin, X. F., et al. (2010). Quantitative phosphoproteomics of proteasome inhibition in multiple myeloma cells. PLoS ONE 5:e13095. doi: 10.1371/journal.pone.0013095
-
(2010)
Plos ONE
, vol.5
-
-
Ge, F.1
Xiao, C.L.2
Bi, L.J.3
Tao, S.C.4
Xiong, S.5
Yin, X.F.6
-
64
-
-
72449132470
-
Autoregulation of co-chaperone BAG3 gene transcription
-
Gentilella, A., and Khalili, K. (2009). Autoregulation of co-chaperone BAG3 gene transcription. J. Cell. Biochem. 108, 1117–1124. doi: 10.1002/jcb.22343
-
(2009)
J. Cell. Biochem.
, vol.108
, pp. 1117-1124
-
-
Gentilella, A.1
Khalili, K.2
-
65
-
-
77958461254
-
BAG3 expression is sustained by FGF2 in neural progenitor cells and impacts cell proliferation
-
Gentilella, A., and Khalili, K. (2010). BAG3 expression is sustained by FGF2 in neural progenitor cells and impacts cell proliferation. Cell Cycle 9, 4245–4247. doi: 10.4161/cc.9.20.13517
-
(2010)
Cell Cycle
, vol.9
, pp. 4245-4247
-
-
Gentilella, A.1
Khalili, K.2
-
66
-
-
79953189657
-
BAG3 expression in glioblastoma cells promotes accumulation of ubiquitinated clients in an Hsp70-dependent manner
-
Gentilella, A., and Khalili, K. (2011). BAG3 expression in glioblastoma cells promotes accumulation of ubiquitinated clients in an Hsp70-dependent manner. J. Biol. Chem. 286, 9205–9215. doi: 10.1074/jbc.M110.175836
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 9205-9215
-
-
Gentilella, A.1
Khalili, K.2
-
67
-
-
50649086143
-
Activation of BAG3 by Egr-1 in response to FGF-2 in neuroblastoma cells
-
Gentilella, A., Passiatore, G., Deshmane, S., Turco, M. C., and Khalili, K. (2008). Activation of BAG3 by Egr-1 in response to FGF-2 in neuroblastoma cells. Oncogene 27, 5011–5018. doi: 10.1038/onc.2008.142
-
(2008)
Oncogene
, vol.27
, pp. 5011-5018
-
-
Gentilella, A.1
Passiatore, G.2
Deshmane, S.3
Turco, M.C.4
Khalili, K.5
-
68
-
-
84883536024
-
What renders TAU Toxic
-
Gotz, J., Xia, D., Leinenga, G., Chew, Y. L., and Nicholas, H. (2013). What renders TAU Toxic. Front. Neurol. 4:72. doi: 10.3389/fneur.2013.00072
-
(2013)
Front. Neurol
, vol.4
, pp. 72
-
-
Gotz, J.1
Xia, D.2
Leinenga, G.3
Chew, Y.L.4
Nicholas, H.5
-
69
-
-
78651322527
-
Co-chaperone BAG3 and adenovirus penton base protein partnership
-
Gout, E., Gutkowska, M., Takayama, S., Reed, J. C., and Chroboczek, J. (2010). Co-chaperone BAG3 and adenovirus penton base protein partnership. J. Cell. Biochem. 111, 699–708. doi: 10.1002/jcb.22756
-
(2010)
J. Cell. Biochem.
, vol.111
, pp. 699-708
-
-
Gout, E.1
Gutkowska, M.2
Takayama, S.3
Reed, J.C.4
Chroboczek, J.5
-
70
-
-
84901070143
-
BAG3 protein expression in melanoma metastatic lymph nodes correlates with patients’ survival
-
Guerriero, L., Chong, K., Franco, R., Rosati, A., De Caro, F., Capunzo, M., et al. (2014). BAG3 protein expression in melanoma metastatic lymph nodes correlates with patients’ survival. Cell Death Dis. 5:e1173. doi: 10.1038/cddis. 2014.143
-
(2014)
Cell Death Dis
, vol.5
-
-
Guerriero, L.1
Chong, K.2
Franco, R.3
Rosati, A.4
De Caro, F.5
Capunzo, M.6
-
71
-
-
79960652801
-
Molecular chaperones in protein folding and proteostasis
-
Hartl, F. U., Bracher, A., and Hayer-Hartl, M. (2011). Molecular chaperones in protein folding and proteostasis. Nature 475, 324–332. doi: 10.1038/nature10317
-
(2011)
Nature
, vol.475
, pp. 324-332
-
-
Hartl, F.U.1
Bracher, A.2
Hayer-Hartl, M.3
-
72
-
-
0037040541
-
Molecular chaperones in the cytosol: From nascent chain to folded protein
-
Hartl, F. U., and Hayer-Hartl, M. (2002). Molecular chaperones in the cytosol: from nascent chain to folded protein. Science 295, 1852–1858. doi: 10.1126/science. 1068408
-
(2002)
Science
, vol.295
, pp. 1852-1858
-
-
Hartl, F.U.1
Hayer-Hartl, M.2
-
73
-
-
0031657807
-
The ubiquitin system
-
Hershko, A., and Ciechanover, A. (1998). The ubiquitin system. Annu. Rev. Biochem. 67, 425–479. doi: 10.1146/annurev.biochem.67.1.425
-
(1998)
Annu. Rev. Biochem.
, vol.67
, pp. 425-479
-
-
Hershko, A.1
Ciechanover, A.2
-
74
-
-
84906794886
-
Proteostasis impairment in protein-misfolding and -aggregation diseases
-
Hipp, M. S., Park, S. H., and Hartl, F. U. (2014). Proteostasis impairment in protein-misfolding and -aggregation diseases. Trends Cell Biol. 24, 506–514. doi: 10.1016/j.tcb.2014.05.003
-
(2014)
Trends Cell Biol
, vol.24
, pp. 506-514
-
-
Hipp, M.S.1
Park, S.H.2
Hartl, F.U.3
-
75
-
-
78549244048
-
BAG3 and Hsc70 interact with actin capping protein CapZ to maintain myofibrillar integrity under mechanical stress
-
Hishiya, A., Kitazawa, T., and Takayama, S. (2010). BAG3 and Hsc70 interact with actin capping protein CapZ to maintain myofibrillar integrity under mechanical stress. Circ. Res. 107, 1220–1231. doi: 10.1161/CIRCRESAHA.110.225649
-
(2010)
Circ. Res.
, vol.107
, pp. 1220-1231
-
-
Hishiya, A.1
Kitazawa, T.2
Takayama, S.3
-
76
-
-
84877615360
-
Therapeutic induction of autophagy to modulate neurodegenerative disease progression
-
Hochfeld, W. E., Lee, S., and Rubinsztein, D. C. (2013). Therapeutic induction of autophagy to modulate neurodegenerative disease progression. Acta Pharmacol. Sin. 34, 600–604. doi: 10.1038/aps.2012.189
-
(2013)
Acta Pharmacol. Sin.
, vol.34
, pp. 600-604
-
-
Hochfeld, W.E.1
Lee, S.2
Rubinsztein, D.C.3
-
77
-
-
0033525582
-
Noncanonical MMS2-encoded ubiquitin-conjugating enzyme functions in assembly of novel polyubiquitin chains for DNA repair
-
Hofmann, R. M., and Pickart, C. M. (1999). Noncanonical MMS2-encoded ubiquitin-conjugating enzyme functions in assembly of novel polyubiquitin chains for DNA repair. Cell 96, 645–653.
-
(1999)
Cell
, vol.96
, pp. 645-653
-
-
Hofmann, R.M.1
Pickart, C.M.2
-
78
-
-
33748801507
-
BAG3 deficiency results in fulminant myopathy and early lethality
-
Homma, S., Iwasaki, M., Shelton, G. D., Engvall, E., Reed, J. C., and Takayama, S. (2006). BAG3 deficiency results in fulminant myopathy and early lethality. Am. J. Pathol. 169, 761–773. doi: 10.2353/ajpath.2006.060250
-
(2006)
Am. J. Pathol.
, vol.169
, pp. 761-773
-
-
Homma, S.1
Iwasaki, M.2
Shelton, G.D.3
Engvall, E.4
Reed, J.C.5
Takayama, S.6
-
79
-
-
84973639326
-
BIS-mediated STAT3 stabilization regulates glioblastoma stem cell-like phenotypes
-
Im, C. N., Yun, H. H., Song, B., Youn, D. Y., Cui, M. N., Kim, H. S., et al. (2016). BIS-mediated STAT3 stabilization regulates glioblastoma stem cell-like phenotypes. Oncotarget 7, 35056–35070. doi: 10.18632/oncotarget.9039
-
(2016)
Oncotarget
, vol.7
, pp. 35056-35070
-
-
Im, C.N.1
Yun, H.H.2
Song, B.3
Youn, D.Y.4
Cui, M.N.5
Kim, H.S.6
-
80
-
-
84965085185
-
BAG3 regulates formation of the SNARE complex and insulin secretion
-
Iorio, V., Festa, M., Rosati, A., Hahne, M., Tiberti, C., Capunzo, M., et al. (2015). BAG3 regulates formation of the SNARE complex and insulin secretion. Cell Death Dis. 6:e1684. doi: 10.1038/cddis.2015.53
-
(2015)
Cell Death Dis
, vol.6
-
-
Iorio, V.1
Festa, M.2
Rosati, A.3
Hahne, M.4
Tiberti, C.5
Capunzo, M.6
-
81
-
-
77956940128
-
BAG3 directly associates with guanine nucleotide exchange factor of Rap1, PDZGEF2, and regulates cell adhesion
-
Iwasaki, M., Tanaka, R., Hishiya, A., Homma, S., Reed, J. C., and Takayama, S. (2010). BAG3 directly associates with guanine nucleotide exchange factor of Rap1, PDZGEF2, and regulates cell adhesion. Biochem. Biophys. Res. Commun. 400, 413–418. doi: 10.1016/j.bbrc.2010.08.092
-
(2010)
Biochem. Biophys. Res. Commun.
, vol.400
, pp. 413-418
-
-
Iwasaki, M.1
Tanaka, R.2
Hishiya, A.3
Homma, S.4
Reed, J.C.5
Takayama, S.6
-
82
-
-
84863441874
-
BAG3 mutations: Another cause of giant axonal neuropathy
-
Jaffer, F., Murphy, S. M., Scoto, M., Healy, E., Rossor, A. M., Brandner, S., et al. (2012). BAG3 mutations: another cause of giant axonal neuropathy. J. Peripher. Nerv. Syst. 17, 210–216. doi: 10.1111/j.1529-8027.2012.00409.x
-
(2012)
J. Peripher. Nerv. Syst.
, vol.17
, pp. 210-216
-
-
Jaffer, F.1
Murphy, S.M.2
Scoto, M.3
Healy, E.4
Rossor, A.M.5
Brandner, S.6
-
83
-
-
84907525554
-
14-3-3 and aggresome formation: Implications in neurodegenerative diseases
-
Jia, B., Wu, Y., and Zhou, Y. (2014). 14-3-3 and aggresome formation: implications in neurodegenerative diseases. Prion 8, 28123.
-
(2014)
Prion
, vol.8
-
-
Jia, B.1
Wu, Y.2
Zhou, Y.3
-
84
-
-
84891738225
-
Autophagy and human diseases
-
Jiang, P., and Mizushima, N. (2014). Autophagy and human diseases. Cell Res. 24, 69–79. doi: 10.1038/cr.2013.161
-
(2014)
Cell Res
, vol.24
, pp. 69-79
-
-
Jiang, P.1
Mizushima, N.2
-
85
-
-
43049162227
-
Mechanism of ubiquitin-chain formation by the human anaphase-promoting complex
-
Jin, L., Williamson, A., Banerjee, S., Philipp, I., and Rape, M. (2008). Mechanism of ubiquitin-chain formation by the human anaphase-promoting complex. Cell 133, 653–665. doi: 10.1016/j.cell.2008.04.012
-
(2008)
Cell
, vol.133
, pp. 653-665
-
-
Jin, L.1
Williamson, A.2
Banerjee, S.3
Philipp, I.4
Rape, M.5
-
86
-
-
84904259934
-
Regulation of autophagy: Modulation of the size and number of autophagosomes
-
Jin, M., and Klionsky, D. J. (2014). Regulation of autophagy: modulation of the size and number of autophagosomes. FEBS Lett. 588, 2457–2463. doi: 10.1016/j.febslet.2014.06.015
-
(2014)
FEBS Lett
, vol.588
, pp. 2457-2463
-
-
Jin, M.1
Klionsky, D.J.2
-
87
-
-
84938289392
-
BAG3 affects the nucleocytoplasmic shuttling of HSF1 upon heat stress
-
Jin, Y. H., Ahn, S. G., and Kim, S. A. (2015). BAG3 affects the nucleocytoplasmic shuttling of HSF1 upon heat stress. Biochem. Biophys. Res. Commun. 464, 561–567. doi: 10.1016/j.bbrc.2015.07.006
-
(2015)
Biochem. Biophys. Res. Commun.
, vol.464
, pp. 561-567
-
-
Jin, Y.H.1
Ahn, S.G.2
Kim, S.A.3
-
88
-
-
79952355107
-
Selective autophagy mediated by autophagic adapter proteins
-
Johansen, T., and Lamark, T. (2011). Selective autophagy mediated by autophagic adapter proteins. Autophagy 7, 279–296.
-
(2011)
Autophagy
, vol.7
, pp. 279-296
-
-
Johansen, T.1
Lamark, T.2
-
89
-
-
0033749379
-
Formation of high molecular weight complexes of mutant Cu, Zn-superoxide dismutase in a mouse model for familial amyotrophic lateral sclerosis
-
Johnston, J. A., Dalton, M. J., Gurney, M. E., and Kopito, R. R. (2000). Formation of high molecular weight complexes of mutant Cu, Zn-superoxide dismutase in a mouse model for familial amyotrophic lateral sclerosis. Proc. Natl. Acad. Sci. U.S.A. 97, 12571–12576. doi: 10.1073/pnas.220417997
-
(2000)
Proc. Natl. Acad. Sci. U.S.A.
, vol.97
, pp. 12571-12576
-
-
Johnston, J.A.1
Dalton, M.J.2
Gurney, M.E.3
Kopito, R.R.4
-
90
-
-
0032576605
-
Aggresomes: A cellular response to misfolded proteins
-
Johnston, J. A., Ward, C. L., and Kopito, R. R. (1998). Aggresomes: a cellular response to misfolded proteins. J. Cell Biol. 143, 1883–1898.
-
(1998)
J. Cell Biol.
, vol.143
, pp. 1883-1898
-
-
Johnston, J.A.1
Ward, C.L.2
Kopito, R.R.3
-
91
-
-
43049155955
-
The BAG proteins: A ubiquitous family of chaperone regulators
-
Kabbage, M., and Dickman, M. B. (2008). The BAG proteins: a ubiquitous family of chaperone regulators. Cell Mol. Life. Sci. 65, 1390–1402. doi: 10.1007/s00018-008-7535-2
-
(2008)
Cell Mol. Life. Sci.
, vol.65
, pp. 1390-1402
-
-
Kabbage, M.1
Dickman, M.B.2
-
92
-
-
77954947810
-
The HSP70 chaperone machinery: J proteins as drivers of functional specificity
-
Kampinga, H. H., and Craig, E. A. (2010). The HSP70 chaperone machinery: J proteins as drivers of functional specificity. Nat. Rev. Mol. Cell Biol. 11, 579–592. doi: 10.1038/nrm2941
-
(2010)
Nat. Rev. Mol. Cell Biol.
, vol.11
, pp. 579-592
-
-
Kampinga, H.H.1
Craig, E.A.2
-
93
-
-
64549097439
-
Guidelines for the nomenclature of the human heat shock proteins
-
Kampinga, H. H., Hageman, J., Vos, M. J., Kubota, H., Tanguay, R. M., Bruford, E. A., et al. (2009). Guidelines for the nomenclature of the human heat shock proteins. Cell Stress Chaperones 14, 105–111. doi: 10.1007/s12192-008-0068-7
-
(2009)
Cell Stress Chaperones
, vol.14
, pp. 105-111
-
-
Kampinga, H.H.1
Hageman, J.2
Vos, M.J.3
Kubota, H.4
Tanguay, R.M.5
Bruford, E.A.6
-
94
-
-
84994201292
-
The cochaperone BAG3 coordinates protein synthesis and autophagy under mechanical strain through spatial regulation of mTORC1
-
Kathage, B., Gehlert, S., Ulbricht, A., Ludecke, L., Tapia, V. E., Orfanos, Z., et al. (2017). The cochaperone BAG3 coordinates protein synthesis and autophagy under mechanical strain through spatial regulation of mTORC1. Biochim. Biophys. Acta 1864, 62–75. doi: 10.1016/j.bbamcr.2016.10.007
-
(2017)
Biochim. Biophys. Acta
, vol.1864
, pp. 62-75
-
-
Kathage, B.1
Gehlert, S.2
Ulbricht, A.3
Ludecke, L.4
Tapia, V.E.5
Orfanos, Z.6
-
95
-
-
0346020435
-
The deacetylase HDAC6 regulates aggresome formation and cell viability in response to misfolded protein stress
-
Kawaguchi, Y., Kovacs, J. J., McLaurin, A., Vance, J. M., Ito, A., and Yao, T. P. (2003). The deacetylase HDAC6 regulates aggresome formation and cell viability in response to misfolded protein stress. Cell 115, 727–738.
-
(2003)
Cell
, vol.115
, pp. 727-738
-
-
Kawaguchi, Y.1
Kovacs, J.J.2
McLaurin, A.3
Vance, J.M.4
Ito, A.5
Yao, T.P.6
-
96
-
-
84964269948
-
The integration of autophagy and cellular trafficking pathways via RAB GAPs
-
Kern, A., Dikic, I., and Behl, C. (2015). The integration of autophagy and cellular trafficking pathways via RAB GAPs. Autophagy 11, 2393–2397. doi: 10.1080/15548627.2015.1110668
-
(2015)
Autophagy
, vol.11
, pp. 2393-2397
-
-
Kern, A.1
Dikic, I.2
Behl, C.3
-
97
-
-
33749346301
-
Modification of proteins by ubiquitin and ubiquitin-like proteins
-
Kerscher, O., Felberbaum, R., and Hochstrasser, M. (2006). Modification of proteins by ubiquitin and ubiquitin-like proteins. Annu. Rev. Cell Dev. Biol. 22, 159–180. doi: 10.1146/annurev.cellbio.22.010605.093503
-
(2006)
Annu. Rev. Cell Dev. Biol.
, vol.22
, pp. 159-180
-
-
Kerscher, O.1
Felberbaum, R.2
Hochstrasser, M.3
-
98
-
-
84955242756
-
Ubiquitin-dependent and independent signals in selective autophagy
-
Khaminets, A., Behl, C., and Dikic, I. (2016). Ubiquitin-dependent and independent signals in selective autophagy. Trends Cell Biol. 26, 6–16. doi: 10.1016/j.tcb.2015.08.010
-
(2016)
Trends Cell Biol
, vol.26
, pp. 6-16
-
-
Khaminets, A.1
Behl, C.2
Dikic, I.3
-
99
-
-
84885415875
-
The natural compound cantharidin induces cancer cell death through inhibition of heat shock protein 70 (HSP70) and Bcl-2-associated athanogene domain 3 (BAG3) expression by blocking heat shock factor 1 (HSF1) binding to promoters
-
Kim, J. A., Kim, Y., Kwon, B. M., and Han, D. C. (2013). The natural compound cantharidin induces cancer cell death through inhibition of heat shock protein 70 (HSP70) and Bcl-2-associated athanogene domain 3 (BAG3) expression by blocking heat shock factor 1 (HSF1) binding to promoters. J. Biol. Chem. 288, 28713–28726. doi: 10.1074/jbc.M113.488346
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 28713-28726
-
-
Kim, J.A.1
Kim, Y.2
Kwon, B.M.3
Han, D.C.4
-
100
-
-
84941618262
-
Fisetin, a dietary flavonoid, induces apoptosis of cancer cells by inhibiting HSF1 activity through blocking its binding to the hsp70 promoter
-
Kim, J. A., Lee, S., Kim, D. E., Kim, M., Kwon, B. M., and Han, D. C. (2015). Fisetin, a dietary flavonoid, induces apoptosis of cancer cells by inhibiting HSF1 activity through blocking its binding to the hsp70 promoter. Carcinogenesis 36, 696–706. doi: 10.1093/carcin/bgv045
-
(2015)
Carcinogenesis
, vol.36
, pp. 696-706
-
-
Kim, J.A.1
Lee, S.2
Kim, D.E.3
Kim, M.4
Kwon, B.M.5
Han, D.C.6
-
101
-
-
84878948560
-
Molecular chaperone functions in protein folding and proteostasis
-
Kim, Y. E., Hipp, M. S., Bracher, A., Hayer-Hartl, M., and Hartl, F. U. (2013). Molecular chaperone functions in protein folding and proteostasis. Annu. Rev. Biochem. 82, 323–355. doi: 10.1146/annurev-biochem-060208-092442
-
(2013)
Annu. Rev. Biochem.
, vol.82
, pp. 323-355
-
-
Kim, Y.E.1
Hipp, M.S.2
Bracher, A.3
Hayer-Hartl, M.4
Hartl, F.U.5
-
102
-
-
85013763791
-
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
-
Klionsky, D. J., Abdelmohsen, K., Abe, A., Abedin, M. J., Abeliovich, H., Acevedo Arozena, A., et al. (2016). Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy 12, 1–222. doi: 10.1080/15548627.2015.1100356
-
(2016)
Autophagy
, vol.12
, pp. 1-222
-
-
Klionsky, D.J.1
Abdelmohsen, K.2
Abe, A.3
Abedin, M.J.4
Abeliovich, H.5
Acevedo Arozena, A.6
-
103
-
-
10744225487
-
A unified nomenclature for yeast autophagy-related genes
-
Klionsky, D. J., Cregg, J. M., Dunn, W. A. Jr., Emr, S. D., Sakai, Y., Sandoval, I. V., et al. (2003). A unified nomenclature for yeast autophagy-related genes. Dev. Cell 5, 539–545.
-
(2003)
Dev. Cell
, vol.5
, pp. 539-545
-
-
Klionsky, D.J.1
Cregg, J.M.2
Dunn, W.A.3
Emr, S.D.4
Sakai, Y.5
Sandoval, I.V.6
-
104
-
-
84898757170
-
Dynamic regulation of macroautophagy by distinctive ubiquitin-like proteins
-
Klionsky, D. J., and Schulman, B. A. (2014). Dynamic regulation of macroautophagy by distinctive ubiquitin-like proteins. Nat. Struct. Mol. Biol. 21, 336–345. doi: 10.1038/nsmb.2787
-
(2014)
Nat. Struct. Mol. Biol.
, vol.21
, pp. 336-345
-
-
Klionsky, D.J.1
Schulman, B.A.2
-
105
-
-
84930871552
-
BAG3: A new player in the heart failure paradigm
-
Knezevic, T., Myers, V. D., Gordon, J., Tilley, D. G., Sharp, T. E. III, Wang, J., et al. (2015). BAG3: a new player in the heart failure paradigm. Heart Fail. Rev. 20, 423–434. doi: 10.1007/s10741-015-9487-6
-
(2015)
Heart Fail. Rev.
, vol.20
, pp. 423-434
-
-
Knezevic, T.1
Myers, V.D.2
Gordon, J.3
Tilley, D.G.4
Sharp, T.E.5
Wang, J.6
-
106
-
-
70350150000
-
The emerging complexity of protein ubiquitination
-
Komander, D. (2009). The emerging complexity of protein ubiquitination. Biochem. Soc. Trans. 37(Pt 5), 937–953. doi: 10.1042/BST0370937
-
(2009)
Biochem. Soc. Trans
, vol.37
, pp. 937-953
-
-
Komander, D.1
-
107
-
-
84861877407
-
The ubiquitin code
-
Komander, D., and Rape, M. (2012). The ubiquitin code. Annu. Rev. Biochem. 81, 203–229. doi: 10.1146/annurev-biochem-060310-170328
-
(2012)
Annu. Rev. Biochem.
, vol.81
, pp. 203-229
-
-
Komander, D.1
Rape, M.2
-
108
-
-
84927912558
-
BAG3 myofibrillar myopathy presenting with cardiomyopathy
-
Konersman, C. G., Bordini, B. J., Scharer, G., Lawlor, M. W., Zangwill, S., Southern, J. F., et al. (2015). BAG3 myofibrillar myopathy presenting with cardiomyopathy. Neuromuscul. Disord. 25, 418–422. doi: 10.1016/j.nmd.2015.01.009
-
(2015)
Neuromuscul. Disord.
, vol.25
, pp. 418-422
-
-
Konersman, C.G.1
Bordini, B.J.2
Scharer, G.3
Lawlor, M.W.4
Zangwill, S.5
Southern, J.F.6
-
109
-
-
0034578389
-
Aggresomes, inclusion bodies and protein aggregation
-
Kopito, R. R. (2000). Aggresomes, inclusion bodies and protein aggregation. Trends Cell Biol. 10, 524–530.
-
(2000)
Trends Cell Biol
, vol.10
, pp. 524-530
-
-
Kopito, R.R.1
-
110
-
-
0025051251
-
Nonselective autophagy of cytosolic enzymes by isolated rat hepatocytes
-
Kopitz, J., Kisen, G. O., Gordon, P. B., Bohley, P., and Seglen, P. O. (1990). Nonselective autophagy of cytosolic enzymes by isolated rat hepatocytes. J. Cell Biol. 111, 941–953.
-
(1990)
J. Cell Biol.
, vol.111
, pp. 941-953
-
-
Kopitz, J.1
Kisen, G.O.2
Gordon, P.B.3
Bohley, P.4
Seglen, P.O.5
-
111
-
-
84946771661
-
BAG3-related myopathy, polyneuropathy and cardiomyopathy with long QT syndrome
-
Kostera-Pruszczyk, A., Suszek, M., Ploski, R., Franaszczyk, M., Potulska-Chromik, A., Pruszczyk, P., et al. (2015). BAG3-related myopathy, polyneuropathy and cardiomyopathy with long QT syndrome. J. Muscle Res. Cell Motil. 36, 423–432. doi: 10.1007/s10974-015-9431-3
-
(2015)
J. Muscle Res. Cell Motil.
, vol.36
, pp. 423-432
-
-
Kostera-Pruszczyk, A.1
Suszek, M.2
Ploski, R.3
Franaszczyk, M.4
Potulska-Chromik, A.5
Pruszczyk, P.6
-
112
-
-
84946122397
-
Modulation of BAG3 expression and proteasomal activity by sAPPalpha does not require membrane-tethered holo-APP
-
Kundu, A., Milosch, N., Antonietti, P., Baumkotter, F., Zymny, A., Muller, U. C., et al. (2016). Modulation of BAG3 expression and proteasomal activity by sAPPalpha does not require membrane-tethered holo-APP. Mol. Neurobiol. 53, 5985–5994. doi: 10.1007/s12035-015-9501-y
-
(2016)
Mol. Neurobiol.
, vol.53
, pp. 5985-5994
-
-
Kundu, A.1
Milosch, N.2
Antonietti, P.3
Baumkotter, F.4
Zymny, A.5
Muller, U.C.6
-
113
-
-
58549086337
-
The co-chaperone BAG3 regulates herpes simplex virus replication
-
Kyratsous, C. A., and Silverstein, S. J. (2008). The co-chaperone BAG3 regulates herpes simplex virus replication. Proc. Natl. Acad. Sci. U.S.A. 105, 20912–20917. doi: 10.1073/pnas.0810656105
-
(2008)
Proc. Natl. Acad. Sci. U.S.A.
, vol.105
, pp. 20912-20917
-
-
Kyratsous, C.A.1
Silverstein, S.J.2
-
114
-
-
84880730823
-
Huntington’s disease: Underlying molecular mechanisms and emerging concepts
-
Labbadia, J., and Morimoto, R. I. (2013). Huntington’s disease: underlying molecular mechanisms and emerging concepts. Trends Biochem. Sci. 38, 378–385. doi: 10.1016/j.tibs.2013.05.003
-
(2013)
Trends Biochem. Sci.
, vol.38
, pp. 378-385
-
-
Labbadia, J.1
Morimoto, R.I.2
-
115
-
-
84930746830
-
The biology of proteostasis in aging and disease
-
Labbadia, J., and Morimoto, R. I. (2015). The biology of proteostasis in aging and disease. Annu. Rev. Biochem. 84, 435–464. doi: 10.1146/annurev-biochem-060614-033955
-
(2015)
Annu. Rev. Biochem.
, vol.84
, pp. 435-464
-
-
Labbadia, J.1
Morimoto, R.I.2
-
116
-
-
84888380983
-
The autophagosome: Origins unknown, biogenesis complex
-
Lamb, C. A., Yoshimori, T., and Tooze, S. A. (2013). The autophagosome: origins unknown, biogenesis complex. Nat. Rev. Mol. Cell Biol. 14, 759–774. doi: 10.1038/nrm3696
-
(2013)
Nat. Rev. Mol. Cell Biol.
, vol.14
, pp. 759-774
-
-
Lamb, C.A.1
Yoshimori, T.2
Tooze, S.A.3
-
117
-
-
84863283173
-
BAG3-related myofibrillar myopathy in a Chinese family
-
Lee, H. C., Cherk, S. W., Chan, S. K., Wong, S., Tong, T. W., Ho, W. S., et al. (2012). BAG3-related myofibrillar myopathy in a Chinese family. Clin. Genet. 81, 394–398. doi: 10.1111/j.1399-0004.2011.01659.x
-
(2012)
Clin. Genet.
, vol.81
, pp. 394-398
-
-
Lee, H.C.1
Cherk, S.W.2
Chan, S.K.3
Wong, S.4
Tong, T.W.5
Ho, W.S.6
-
118
-
-
0033523874
-
Bis, a Bcl-2-binding protein that synergizes with Bcl-2 in preventing cell death
-
Lee, J. H., Takahashi, T., Yasuhara, N., Inazawa, J., Kamada, S., and Tsujimoto, Y. (1999). Bis, a Bcl-2-binding protein that synergizes with Bcl-2 in preventing cell death. Oncogene 18, 6183–6190. doi: 10.1038/sj.onc.1203043
-
(1999)
Oncogene
, vol.18
, pp. 6183-6190
-
-
Lee, J.H.1
Takahashi, T.2
Yasuhara, N.3
Inazawa, J.4
Kamada, S.5
Tsujimoto, Y.6
-
119
-
-
84920420065
-
BAG3 facilitates the clearance of endogenous tau in primary neurons
-
Lei, Z., Brizzee, C., and Johnson, G. V. (2015). BAG3 facilitates the clearance of endogenous tau in primary neurons. Neurobiol. Aging 36, 241–248. doi: 10.1016/j.neurobiolaging.2014.08.012
-
(2015)
Neurobiol. Aging
, vol.36
, pp. 241-248
-
-
Lei, Z.1
Brizzee, C.2
Johnson, G.V.3
-
120
-
-
84884588730
-
PKCdelta-mediated phosphorylation of BAG3 at Ser187 site induces epithelial-mesenchymal transition and enhances invasiveness in thyroid cancer FRO cells
-
Li, N., Du, Z. X., Zong, Z. H., Liu, B. Q., Li, C., Zhang, Q., et al. (2013). PKCdelta-mediated phosphorylation of BAG3 at Ser187 site induces epithelial-mesenchymal transition and enhances invasiveness in thyroid cancer FRO cells. Oncogene 32, 4539–4548. doi: 10.1038/onc.2012.466
-
(2013)
Oncogene
, vol.32
, pp. 4539-4548
-
-
Li, N.1
Du, Z.X.2
Zong, Z.H.3
Liu, B.Q.4
Li, C.5
Zhang, Q.6
-
121
-
-
84929597660
-
Validation of the Hsp70-Bag3 protein-protein interaction as a potential therapeutic target in cancer
-
Li, X., Colvin, T., Rauch, J. N., Acosta-Alvear, D., Kampmann, M., Dunyak, B., et al. (2015). Validation of the Hsp70-Bag3 protein-protein interaction as a potential therapeutic target in cancer. Mol. Cancer Ther. 14, 642–648. doi: 10.1158/1535-7163.MCT-14-0650
-
(2015)
Mol. Cancer Ther.
, vol.14
, pp. 642-648
-
-
Li, X.1
Colvin, T.2
Rauch, J.N.3
Acosta-Alvear, D.4
Kampmann, M.5
Dunyak, B.6
-
122
-
-
0035902997
-
The anti-apoptotic protein BAG-3 is overexpressed in pancreatic cancer and induced by heat stress in pancreatic cancer cell lines
-
Liao, Q., Ozawa, F., Friess, H., Zimmermann, A., Takayama, S., Reed, J. C., et al. (2001). The anti-apoptotic protein BAG-3 is overexpressed in pancreatic cancer and induced by heat stress in pancreatic cancer cell lines. FEBS Lett. 503, 151–157.
-
(2001)
FEBS Lett
, vol.503
, pp. 151-157
-
-
Liao, Q.1
Ozawa, F.2
Friess, H.3
Zimmermann, A.4
Takayama, S.5
Reed, J.C.6
-
123
-
-
84979306721
-
The life cycle of the 26S proteasome: From birth, through regulation and function, and onto its death
-
Livneh, I., Cohen-Kaplan, V., Cohen-Rosenzweig, C., Avni, N., and Ciechanover, A. (2016). The life cycle of the 26S proteasome: from birth, through regulation and function, and onto its death. Cell Res. 26, 869–885. doi: 10.1038/cr.2016.86
-
(2016)
Cell Res
, vol.26
, pp. 869-885
-
-
Livneh, I.1
Cohen-Kaplan, V.2
Cohen-Rosenzweig, C.3
Avni, N.4
Ciechanover, A.5
-
124
-
-
84956643290
-
Knockdown of BAG3 sensitizes bladder cancer cells to treatment with the BH3 mimetic ABT-737
-
Mani, J., Antonietti, P., Rakel, S., Blaheta, R., Bartsch, G., Haferkamp, A., et al. (2016). Knockdown of BAG3 sensitizes bladder cancer cells to treatment with the BH3 mimetic ABT-737. World J. Urol. 34, 197–205. doi: 10.1007/s00345-015-1616-2
-
(2016)
World J. Urol.
, vol.34
, pp. 197-205
-
-
Mani, J.1
Antonietti, P.2
Rakel, S.3
Blaheta, R.4
Bartsch, G.5
Haferkamp, A.6
-
125
-
-
4344618621
-
Pathophysiology of chaperone-mediated autophagy
-
Massey, A., Kiffin, R., and Cuervo, A. M. (2004). Pathophysiology of chaperone-mediated autophagy. Int. J. Biochem. Cell Biol. 36, 2420–2434. doi: 10.1016/j.biocel.2004.04.010
-
(2004)
Int. J. Biochem. Cell Biol.
, vol.36
, pp. 2420-2434
-
-
Massey, A.1
Kiffin, R.2
Cuervo, A.M.3
-
126
-
-
17044387386
-
Hsp70 chaperones: Cellular functions and molecular mechanism
-
Mayer, M. P., and Bukau, B. (2005). Hsp70 chaperones: cellular functions and molecular mechanism. Cell Mol. Life. Sci. 62, 670–684. doi: 10.1007/s00018-004-4464-6
-
(2005)
Cell Mol. Life. Sci.
, vol.62
, pp. 670-684
-
-
Mayer, M.P.1
Bukau, B.2
-
127
-
-
72449190234
-
Caught in the middle: The role of Bag3 in disease
-
McCollum, A. K., Casagrande, G., and Kohn, E. C. (2009). Caught in the middle: the role of Bag3 in disease. Biochem. J. 425, e1-3. doi: 10.1042/BJ20091739
-
(2009)
Biochem. J
, vol.425
, pp. e1-e3
-
-
McCollum, A.K.1
Casagrande, G.2
Kohn, E.C.3
-
128
-
-
55949136614
-
Quantitative analysis of global ubiquitination in HeLa cells by mass spectrometry
-
Meierhofer, D., Wang, X., Huang, L., and Kaiser, P. (2008). Quantitative analysis of global ubiquitination in HeLa cells by mass spectrometry. J. Proteome Res. 7, 4566–4576. doi: 10.1021/pr800468j
-
(2008)
J. Proteome Res.
, vol.7
, pp. 4566-4576
-
-
Meierhofer, D.1
Wang, X.2
Huang, L.3
Kaiser, P.4
-
129
-
-
84919754881
-
WW domain of BAG3 is required for the induction of autophagy in glioma cells
-
Merabova, N., Sariyer, I. K., Saribas, A. S., Knezevic, T., Gordon, J., Turco, M. C., et al. (2015). WW domain of BAG3 is required for the induction of autophagy in glioma cells. J. Cell. Physiol. 230, 831–841. doi: 10.1002/jcp.24811
-
(2015)
J. Cell. Physiol.
, vol.230
, pp. 831-841
-
-
Merabova, N.1
Sariyer, I.K.2
Saribas, A.S.3
Knezevic, T.4
Gordon, J.5
Turco, M.C.6
-
130
-
-
79959999581
-
Microautophagy in mammalian cells: Revisiting a 40-year-old conundrum
-
Mijaljica, D., Prescott, M., and Devenish, R. J. (2011). Microautophagy in mammalian cells: revisiting a 40-year-old conundrum. Autophagy 7, 673–682.
-
(2011)
Autophagy
, vol.7
, pp. 673-682
-
-
Mijaljica, D.1
Prescott, M.2
Devenish, R.J.3
-
131
-
-
84907166419
-
BAG3 induces the sequestration of proteasomal clients into cytoplasmic puncta: Implications for a proteasome-to-autophagy switch
-
Minoia, M., Boncoraglio, A., Vinet, J., Morelli, F. F., Brunsting, J. F., Poletti, A., et al. (2014). BAG3 induces the sequestration of proteasomal clients into cytoplasmic puncta: implications for a proteasome-to-autophagy switch. Autophagy 10, 1603–1621. doi: 10.4161/auto.29409
-
(2014)
Autophagy
, vol.10
, pp. 1603-1621
-
-
Minoia, M.1
Boncoraglio, A.2
Vinet, J.3
Morelli, F.F.4
Brunsting, J.F.5
Poletti, A.6
-
132
-
-
80054025654
-
The role of Atg proteins in autophagosome formation
-
Mizushima, N., Yoshimori, T., and Ohsumi, Y. (2011). The role of Atg proteins in autophagosome formation. Annu. Rev. Cell Dev. Biol. 27, 107–132. doi: 10.1146/annurev-cellbio-092910-154005
-
(2011)
Annu. Rev. Cell Dev. Biol.
, vol.27
, pp. 107-132
-
-
Mizushima, N.1
Yoshimori, T.2
Ohsumi, Y.3
-
133
-
-
84868115008
-
Protein homeostasis, aging and Alzheimer’s disease
-
Morawe, T., Hiebel, C., Kern, A., and Behl, C. (2012). Protein homeostasis, aging and Alzheimer’s disease. Mol. Neurobiol. 46, 41–54. doi: 10.1007/s12035-012-8246-0
-
(2012)
Mol. Neurobiol.
, vol.46
, pp. 41-54
-
-
Morawe, T.1
Hiebel, C.2
Kern, A.3
Behl, C.4
-
134
-
-
85007614220
-
2’-Hydroxycinnamaldehyde induces apoptosis through HSF1-mediated BAG3 expression
-
Nguyen, H. A., and Kim, S. A. (2017). 2’-Hydroxycinnamaldehyde induces apoptosis through HSF1-mediated BAG3 expression. Int. J. Oncol. 50, 283–289. doi: 10.3892/ijo.2016.3790
-
(2017)
Int. J. Oncol.
, vol.50
, pp. 283-289
-
-
Nguyen, H.A.1
Kim, S.A.2
-
135
-
-
84861362268
-
NF-kappaB regulates protein quality control after heat stress through modulation of the BAG3-HspB8 complex
-
Nivon, M., Abou-Samra, M., Richet, E., Guyot, B., Arrigo, A. P., and Kretz-Remy, C. (2012). NF-kappaB regulates protein quality control after heat stress through modulation of the BAG3-HspB8 complex. J. Cell Sci. 125(Pt 5), 1141–1151. doi: 10.1242/jcs.091041
-
(2012)
J. Cell Sci
, vol.125
, pp. 1141-1151
-
-
Nivon, M.1
Abou-Samra, M.2
Richet, E.3
Guyot, B.4
Arrigo, A.P.5
Kretz-Remy, C.6
-
136
-
-
84882254367
-
The role of autophagy in neurodegenerative disease
-
Nixon, R. A. (2013). The role of autophagy in neurodegenerative disease. Nat. Med. 19, 983–997. doi: 10.1038/nm.3232
-
(2013)
Nat. Med.
, vol.19
, pp. 983-997
-
-
Nixon, R.A.1
-
137
-
-
79955929421
-
Genome-wide studies of copy number variation and exome sequencing identify rare variants in BAG3 as a cause of dilated cardiomyopathy
-
Norton, N., Li, D., Rieder, M. J., Siegfried, J. D., Rampersaud, E., Zuchner, S., et al. (2011). Genome-wide studies of copy number variation and exome sequencing identify rare variants in BAG3 as a cause of dilated cardiomyopathy. Am. J. Hum. Genet. 88, 273–282. doi: 10.1016/j.ajhg.2011.01.016
-
(2011)
Am. J. Hum. Genet.
, vol.88
, pp. 273-282
-
-
Norton, N.1
Li, D.2
Rieder, M.J.3
Siegfried, J.D.4
Rampersaud, E.5
Zuchner, S.6
-
138
-
-
77954034456
-
Inheritance patterns and phenotypic features of myofibrillar myopathy associated with a BAG3 mutation
-
Odgerel, Z., Sarkozy, A., Lee, H. S., McKenna, C., Rankin, J., Straub, V., et al. (2010). Inheritance patterns and phenotypic features of myofibrillar myopathy associated with a BAG3 mutation. Neuromuscul. Disord. 20, 438–442. doi: 10.1016/j.nmd.2010.05.004
-
(2010)
Neuromuscul. Disord.
, vol.20
, pp. 438-442
-
-
Odgerel, Z.1
Sarkozy, A.2
Lee, H.S.3
McKenna, C.4
Rankin, J.5
Straub, V.6
-
139
-
-
84856071893
-
Protein aggregates are recruited to aggresome by histone deacetylase 6 via unanchored ubiquitin C termini
-
Ouyang, H., Ali, Y. O., Ravichandran, M., Dong, A., Qiu, W., MacKenzie, F., et al. (2012). Protein aggregates are recruited to aggresome by histone deacetylase 6 via unanchored ubiquitin C termini. J. Biol. Chem. 287, 2317–2327. doi: 10.1074/jbc.M111.273730
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 2317-2327
-
-
Ouyang, H.1
Ali, Y.O.2
Ravichandran, M.3
Dong, A.4
Qiu, W.5
Mackenzie, F.6
-
140
-
-
0037464447
-
Regulation by heavy metals and temperature of the human BAG-3 gene, a modulator of Hsp70 activity
-
Pagliuca, M. G., Lerose, R., Cigliano, S., and Leone, A. (2003). Regulation by heavy metals and temperature of the human BAG-3 gene, a modulator of Hsp70 activity. FEBS Lett. 541, 11–15.
-
(2003)
FEBS Lett
, vol.541
, pp. 11-15
-
-
Pagliuca, M.G.1
Lerose, R.2
Cigliano, S.3
Leone, A.4
-
141
-
-
34548259958
-
P62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy
-
Pankiv, S., Clausen, T. H., Lamark, T., Brech, A., Bruun, J. A., Outzen, H., et al. (2007). p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy. J. Biol. Chem. 282, 24131–24145. doi: 10.1074/jbc.M702824200
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 24131-24145
-
-
Pankiv, S.1
Clausen, T.H.2
Lamark, T.3
Brech, A.4
Bruun, J.A.5
Outzen, H.6
-
142
-
-
84892569830
-
An overview of autophagy: Morphology, mechanism, and regulation
-
Parzych, K. R., and Klionsky, D. J. (2014). An overview of autophagy: morphology, mechanism, and regulation. Antioxid. Redox. Signal. 20, 460–473. doi: 10.1089/ars.2013.5371
-
(2014)
Antioxid. Redox. Signal.
, vol.20
, pp. 460-473
-
-
Parzych, K.R.1
Klionsky, D.J.2
-
143
-
-
84920393148
-
Proteomic analysis reveals a role for Bcl2-associated athanogene 3 and major vault protein in resistance to apoptosis in senescent cells by regulating ERK1/2 activation
-
Pasillas, M. P., Shields, S., Reilly, R., Strnadel, J., Behl, C., Park, R., et al. (2015). Proteomic analysis reveals a role for Bcl2-associated athanogene 3 and major vault protein in resistance to apoptosis in senescent cells by regulating ERK1/2 activation. Mol. Cell. Proteomics 14, 1–14. doi: 10.1074/mcp.M114.037697
-
(2015)
Mol. Cell. Proteomics
, vol.14
, pp. 1-14
-
-
Pasillas, M.P.1
Shields, S.2
Reilly, R.3
Strnadel, J.4
Behl, C.5
Park, R.6
-
144
-
-
0041706156
-
A proteomics approach to understanding protein ubiquitination
-
Peng, J., Schwartz, D., Elias, J. E., Thoreen, C. C., Cheng, D., Marsischky, G., et al. (2003). A proteomics approach to understanding protein ubiquitination. Nat. Biotechnol. 21, 921–926. doi: 10.1038/nbt849
-
(2003)
Nat. Biotechnol.
, vol.21
, pp. 921-926
-
-
Peng, J.1
Schwartz, D.2
Elias, J.E.3
Thoreen, C.C.4
Cheng, D.5
Marsischky, G.6
-
145
-
-
0034791090
-
Ubiquitin enters the new millennium
-
Pickart, C. M. (2001). Ubiquitin enters the new millennium. Mol. Cell 8, 499–504.
-
(2001)
Mol. Cell
, vol.8
, pp. 499-504
-
-
Pickart, C.M.1
-
146
-
-
84965085833
-
NIK is required for NF-kappaB-mediated induction of BAG3 upon inhibition of constitutive protein degradation pathways
-
Rapino, F., Abhari, B. A., Jung, M., and Fulda, S. (2015). NIK is required for NF-kappaB-mediated induction of BAG3 upon inhibition of constitutive protein degradation pathways. Cell Death Dis. 6:e1692. doi: 10.1038/cddis.2014.584
-
(2015)
Cell Death Dis
, vol.6
-
-
Rapino, F.1
Abhari, B.A.2
Jung, M.3
Fulda, S.4
-
147
-
-
85006961032
-
BAG3 is a modular, scaffolding protein that physically links heat shock protein 70 (Hsp70) to the small heat shock proteins
-
Rauch, J. N., Tse, E., Freilich, R., Mok, S. A., Makley, L. N., Southworth, D. R., et al. (2017). BAG3 is a modular, scaffolding protein that physically links heat shock protein 70 (Hsp70) to the small heat shock proteins. J. Mol. Biol. 429, 128–141. doi: 10.1016/j.jmb.2016.11.013
-
(2017)
J. Mol. Biol.
, vol.429
, pp. 128-141
-
-
Rauch, J.N.1
Tse, E.2
Freilich, R.3
Mok, S.A.4
Makley, L.N.5
Southworth, D.R.6
-
148
-
-
84922623224
-
The cleavage product of amyloid-beta protein precursor sAbetaPPalpha modulates BAG3-dependent aggresome formation and enhances cellular proteasomal activity
-
Renziehausen, J., Hiebel, C., Nagel, H., Kundu, A., Kins, S., Kogel, D., et al. (2015). The cleavage product of amyloid-beta protein precursor sAbetaPPalpha modulates BAG3-dependent aggresome formation and enhances cellular proteasomal activity. J. Alzheimers. Dis. 44, 879–896. doi: 10.3233/JAD-140600
-
(2015)
J. Alzheimers. Dis
, vol.44
, pp. 879-896
-
-
Renziehausen, J.1
Hiebel, C.2
Nagel, H.3
Kundu, A.4
Kins, S.5
Kogel, D.6
-
149
-
-
84875441083
-
The changing scene of amyotrophic lateral sclerosis
-
Robberecht, W., and Philips, T. (2013). The changing scene of amyotrophic lateral sclerosis. Nat. Rev. Neurosci. 14, 248–264. doi: 10.1038/nrn3430
-
(2013)
Nat. Rev. Neurosci.
, vol.14
, pp. 248-264
-
-
Robberecht, W.1
Philips, T.2
-
150
-
-
84964491330
-
BAG3 regulates total MAP1LC3B protein levels through a translational but not transcriptional mechanism
-
Rodriguez, A. E., Lopez-Crisosto, C., Pena-Oyarzun, D., Salas, D., Parra, V., Quiroga, C., et al. (2016). BAG3 regulates total MAP1LC3B protein levels through a translational but not transcriptional mechanism. Autophagy 12, 287–296. doi: 10.1080/15548627.2015.1124225
-
(2016)
Autophagy
, vol.12
, pp. 287-296
-
-
Rodriguez, A.E.1
Lopez-Crisosto, C.2
Pena-Oyarzun, D.3
Salas, D.4
Parra, V.5
Quiroga, C.6
-
151
-
-
84892859905
-
Interactions between autophagy receptors and ubiquitin-like proteins form the molecular basis for selective autophagy
-
Rogov, V., Dotsch, V., Johansen, T., and Kirkin, V. (2014). Interactions between autophagy receptors and ubiquitin-like proteins form the molecular basis for selective autophagy. Mol. Cell 53, 167–178. doi: 10.1016/j.molcel.2013.12.014
-
(2014)
Mol. Cell
, vol.53
, pp. 167-178
-
-
Rogov, V.1
Dotsch, V.2
Johansen, T.3
Kirkin, V.4
-
152
-
-
34447104604
-
Apoptosis inhibition in cancer cells: A novel molecular pathway that involves BAG3 protein
-
Rosati, A., Ammirante, M., Gentilella, A., Basile, A., Festa, M., Pascale, M., et al. (2007a). Apoptosis inhibition in cancer cells: a novel molecular pathway that involves BAG3 protein. Int. J. Biochem. Cell Biol. 39, 1337–1342. doi: 10.1016/j.biocel.2007.03.007
-
(2007)
Int. J. Biochem. Cell Biol.
, vol.39
, pp. 1337-1342
-
-
Rosati, A.1
Ammirante, M.2
Gentilella, A.3
Basile, A.4
Festa, M.5
Pascale, M.6
-
153
-
-
84946220080
-
BAG3 promotes pancreatic ductal adenocarcinoma growth by activating stromal macrophages
-
Rosati, A., Basile, A., D’Auria, R., d’Avenia, M., De Marco, M., Falco, A., et al. (2015). BAG3 promotes pancreatic ductal adenocarcinoma growth by activating stromal macrophages. Nat. Commun. 6:8695. doi: 10.1038/ncomms9695
-
(2015)
Nat. Commun.
, vol.6
, pp. 8695
-
-
Rosati, A.1
Basile, A.2
D’Auria, R.3
D’Avenia, M.4
De Marco, M.5
Falco, A.6
-
154
-
-
84868122918
-
Expression of the antiapoptotic protein BAG3 is a feature of pancreatic adenocarcinoma and its overexpression is associated with poorer survival
-
Rosati, A., Bersani, S., Tavano, F., Dalla Pozza, E., De Marco, M., Palmieri, M., et al. (2012). Expression of the antiapoptotic protein BAG3 is a feature of pancreatic adenocarcinoma and its overexpression is associated with poorer survival. Am. J. Pathol. 181, 1524–1529. doi: 10.1016/j.ajpath.2012.07.016
-
(2012)
Am. J. Pathol.
, vol.181
, pp. 1524-1529
-
-
Rosati, A.1
Bersani, S.2
Tavano, F.3
Dalla Pozza, E.4
De Marco, M.5
Palmieri, M.6
-
155
-
-
79960008971
-
BAG3: A multifaceted protein that regulates major cell pathways
-
Rosati, A., Graziano, V., De Laurenzi, V., Pascale, M., and Turco, M. C. (2011). BAG3: a multifaceted protein that regulates major cell pathways. Cell Death Dis. 2:e141. doi: 10.1038/cddis.2011.24
-
(2011)
Cell Death Dis
, vol.2
-
-
Rosati, A.1
Graziano, V.2
De Laurenzi, V.3
Pascale, M.4
Turco, M.C.5
-
156
-
-
33846584070
-
Evidence for BAG3 modulation of HIV-1 gene transcription
-
Rosati, A., Leone, A., Del Valle, L., Amini, S., Khalili, K., and Turco, M. C. (2007b). Evidence for BAG3 modulation of HIV-1 gene transcription. J. Cell. Physiol. 210, 676–683. doi: 10.1002/jcp.20865
-
(2007)
J. Cell. Physiol.
, vol.210
, pp. 676-683
-
-
Rosati, A.1
Leone, A.2
Del Valle, L.3
Amini, S.4
Khalili, K.5
Turco, M.C.6
-
157
-
-
84863230500
-
Assembly and function of the proteasome
-
Saeki, Y., and Tanaka, K. (2012). Assembly and function of the proteasome. Methods Mol. Biol. 832, 315–337. doi: 10.1007/978-1-61779-474-2_22
-
(2012)
Methods Mol. Biol.
, vol.832
, pp. 315-337
-
-
Saeki, Y.1
Tanaka, K.2
-
158
-
-
84886412961
-
Chaperone machines for protein folding, unfolding and disaggregation
-
Saibil, H. (2013). Chaperone machines for protein folding, unfolding and disaggregation. Nat. Rev. Mol. Cell Biol. 14, 630–642. doi: 10.1038/nrm3658
-
(2013)
Nat. Rev. Mol. Cell Biol.
, vol.14
, pp. 630-642
-
-
Saibil, H.1
-
159
-
-
84859432401
-
Mutations affecting the cytoplasmic functions of the co-chaperone DNAJB6 cause limb-girdle muscular dystrophy
-
S1–S2
-
Sarparanta, J., Jonson, P. H., Golzio, C., Sandell, S., Luque, H., Screen, M., et al. (2012). Mutations affecting the cytoplasmic functions of the co-chaperone DNAJB6 cause limb-girdle muscular dystrophy. Nat. Genet. 44, 450–455, S1–S2. doi: 10.1038/ng.1103
-
(2012)
Nat. Genet.
, vol.44
, pp. 450-455
-
-
Sarparanta, J.1
Jonson, P.H.2
Golzio, C.3
Sandell, S.4
Luque, H.5
Screen, M.6
-
160
-
-
84901833411
-
Autophagy and human disease: Emerging themes
-
Schneider, J. L., and Cuervo, A. M. (2014). Autophagy and human disease: emerging themes. Curr. Opin. Genet. Dev. 26, 16–23. doi: 10.1016/j.gde.2014.04.003
-
(2014)
Curr. Opin. Genet. Dev.
, vol.26
, pp. 16-23
-
-
Schneider, J.L.1
Cuervo, A.M.2
-
161
-
-
45849091944
-
Structure of the Hsp110:Hsc70 nucleotide exchange machine
-
Schuermann, J. P., Jiang, J., Cuellar, J., Llorca, O., Wang, L., Gimenez, L. E., et al. (2008). Structure of the Hsp110:Hsc70 nucleotide exchange machine. Mol. Cell. 31, 232–243. doi: 10.1016/j.molcel.2008.05.006
-
(2008)
Mol. Cell.
, vol.31
, pp. 232-243
-
-
Schuermann, J.P.1
Jiang, J.2
Cuellar, J.3
Llorca, O.4
Wang, L.5
Gimenez, L.E.6
-
162
-
-
84855516743
-
The HSPB8-BAG3 chaperone complex is upregulated in astrocytes in the human brain affected by protein aggregation diseases
-
Seidel, K., Vinet, J., Dunnen, W. F., Brunt, E. R., Meister, M., Boncoraglio, A., et al. (2012). The HSPB8-BAG3 chaperone complex is upregulated in astrocytes in the human brain affected by protein aggregation diseases. Neuropathol. Appl. Neurobiol. 38, 39–53. doi: 10.1111/j.1365-2990.2011.01198.x
-
(2012)
Neuropathol. Appl. Neurobiol.
, vol.38
, pp. 39-53
-
-
Seidel, K.1
Vinet, J.2
Dunnen, W.F.3
Brunt, E.R.4
Meister, M.5
Boncoraglio, A.6
-
163
-
-
77956392191
-
Myofibrillar myopathies
-
Selcen, D. (2010). Myofibrillar myopathies. Curr. Opin. Neurol. 23, 477–481. doi: 10.1097/WCO.0b013e32833d38b0
-
(2010)
Curr. Opin. Neurol.
, vol.23
, pp. 477-481
-
-
Selcen, D.1
-
164
-
-
60849131479
-
Mutation in BAG3 causes severe dominant childhood muscular dystrophy
-
Selcen, D., Muntoni, F., Burton, B. K., Pegoraro, E., Sewry, C., Bite, A. V., et al. (2009). Mutation in BAG3 causes severe dominant childhood muscular dystrophy. Ann. Neurol. 65, 83–89. doi: 10.1002/ana.21553
-
(2009)
Ann. Neurol
, vol.65
, pp. 83-89
-
-
Selcen, D.1
Muntoni, F.2
Burton, B.K.3
Pegoraro, E.4
Sewry, C.5
Bite, A.V.6
-
165
-
-
84906543280
-
Unusual multisystemic involvement and a novel BAG3 mutation revealed by NGS screening in a large cohort of myofibrillar myopathies
-
Semmler, A. L., Sacconi, S., Bach, J. E., Liebe, C., Burmann, J., Kley, R. A., et al. (2014). Unusual multisystemic involvement and a novel BAG3 mutation revealed by NGS screening in a large cohort of myofibrillar myopathies. Orphanet J. Rare Dis. 9:121. doi: 10.1186/s13023-014-0121-9
-
(2014)
Orphanet J. Rare Dis
, vol.9
, pp. 121
-
-
Semmler, A.L.1
Sacconi, S.2
Bach, J.E.3
Liebe, C.4
Burmann, J.5
Kley, R.A.6
-
166
-
-
84938974589
-
Hsp70 in cancer: Back to the future
-
Sherman, M. Y., and Gabai, V. L. (2015). Hsp70 in cancer: back to the future. Oncogene 34, 4153–4161. doi: 10.1038/onc.2014.349
-
(2015)
Oncogene
, vol.34
, pp. 4153-4161
-
-
Sherman, M.Y.1
Gabai, V.L.2
-
167
-
-
84892161646
-
The Atg8 family: Multifunctional ubiquitin-like key regulators of autophagy
-
Slobodkin, M. R., and Elazar, Z. (2013). The Atg8 family: multifunctional ubiquitin-like key regulators of autophagy. Essays Biochem. 55, 51–64. doi: 10.1042/bse0550051
-
(2013)
Essays Biochem
, vol.55
, pp. 51-64
-
-
Slobodkin, M.R.1
Elazar, Z.2
-
168
-
-
77957264378
-
Activation of heat shock factor 1 plays a role in pyrrolidine dithiocarbamate-mediated expression of the co-chaperone BAG3
-
Song, S., Kole, S., Precht, P., Pazin, M. J., and Bernier, M. (2010). Activation of heat shock factor 1 plays a role in pyrrolidine dithiocarbamate-mediated expression of the co-chaperone BAG3. Int. J. Biochem. Cell Biol. 42, 1856–1863. doi: 10.1016/j.biocel.2010.07.021
-
(2010)
Int. J. Biochem. Cell Biol.
, vol.42
, pp. 1856-1863
-
-
Song, S.1
Kole, S.2
Precht, P.3
Pazin, M.J.4
Bernier, M.5
-
169
-
-
84901815187
-
Cargo recognition and trafficking in selective autophagy
-
Stolz, A., Ernst, A., and Dikic, I. (2014). Cargo recognition and trafficking in selective autophagy. Nat. Cell Biol. 16, 495–501. doi: 10.1038/ncb2979
-
(2014)
Nat. Cell Biol.
, vol.16
, pp. 495-501
-
-
Stolz, A.1
Ernst, A.2
Dikic, I.3
-
170
-
-
0034790768
-
Molecular chaperone targeting and regulation by BAG family proteins
-
Takayama, S., and Reed, J. C. (2001). Molecular chaperone targeting and regulation by BAG family proteins. Nat. Cell Biol. 3, E237–E241. doi: 10.1038/ncb1001-e237
-
(2001)
Nat. Cell Biol
, vol.3
, pp. E237-E241
-
-
Takayama, S.1
Reed, J.C.2
-
171
-
-
0033534588
-
An evolutionarily conserved family of Hsp70/Hsc70 molecular chaperone regulators
-
Takayama, S., Xie, Z., and Reed, J. C. (1999). An evolutionarily conserved family of Hsp70/Hsc70 molecular chaperone regulators. J. Biol. Chem. 274, 781–786.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 781-786
-
-
Takayama, S.1
Xie, Z.2
Reed, J.C.3
-
172
-
-
0034602845
-
Recognition of the polyubiquitin proteolytic signal
-
Thrower, J. S., Hoffman, L., Rechsteiner, M., and Pickart, C. M. (2000). Recognition of the polyubiquitin proteolytic signal. EMBO J. 19, 94–102. doi: 10.1093/emboj/19.1.94
-
(2000)
EMBO J
, vol.19
, pp. 94-102
-
-
Thrower, J.S.1
Hoffman, L.2
Rechsteiner, M.3
Pickart, C.M.4
-
173
-
-
84978695924
-
Familial dilated cardiomyopathy caused by a novel frameshift in the BAG3 gene
-
Toro, R., Perez-Serra, A., Campuzano, O., Moncayo-Arlandi, J., Allegue, C., Iglesias, A., et al. (2016). Familial dilated cardiomyopathy caused by a novel frameshift in the BAG3 gene. PLoS ONE 11:e0158730. doi: 10.1371/journal.pone.0158730
-
(2016)
Plos ONE
, vol.11
-
-
Toro, R.1
Perez-Serra, A.2
Campuzano, O.3
Moncayo-Arlandi, J.4
Allegue, C.5
Iglesias, A.6
-
174
-
-
84881333631
-
Chaperone-assisted proteostasis is essential for mechanotransduction in mammalian cells
-
Ulbricht, A., Arndt, V., and Hohfeld, J. (2013a). Chaperone-assisted proteostasis is essential for mechanotransduction in mammalian cells. Commun. Integr. Biol. 6:e24925. doi: 10.4161/cib.24925
-
(2013)
Commun. Integr. Biol.
, vol.6
-
-
Ulbricht, A.1
Arndt, V.2
Hohfeld, J.3
-
175
-
-
84875210317
-
Cellular mechanotransduction relies on tension-induced and chaperone-assisted autophagy
-
Ulbricht, A., Eppler, F. J., Tapia, V. E., van der Ven, P. F., Hampe, N., Hersch, N., et al. (2013b). Cellular mechanotransduction relies on tension-induced and chaperone-assisted autophagy. Curr. Biol. 23, 430–435. doi: 10.1016/j.cub.2013.01.064
-
(2013)
Curr. Biol.
, vol.23
, pp. 430-435
-
-
Ulbricht, A.1
Eppler, F.J.2
Tapia, V.E.3
Van Der Ven, P.F.4
Hampe, N.5
Hersch, N.6
-
176
-
-
84943766934
-
Induction and adaptation of chaperone-assisted selective autophagy CASA in response to resistance exercise in human skeletal muscle
-
Ulbricht, A., Gehlert, S., Leciejewski, B., Schiffer, T., Bloch, W., and Hohfeld, J. (2015). Induction and adaptation of chaperone-assisted selective autophagy CASA in response to resistance exercise in human skeletal muscle. Autophagy 11, 538–546. doi: 10.1080/15548627.2015.1017186
-
(2015)
Autophagy
, vol.11
, pp. 538-546
-
-
Ulbricht, A.1
Gehlert, S.2
Leciejewski, B.3
Schiffer, T.4
Bloch, W.5
Hohfeld, J.6
-
177
-
-
80052186988
-
A genome-wide association study identifies two loci associated with heart failure due to dilated cardiomyopathy
-
Villard, E., Perret, C., Gary, F., Proust, C., Dilanian, G., Hengstenberg, C., et al. (2011). A genome-wide association study identifies two loci associated with heart failure due to dilated cardiomyopathy. Eur. Heart J. 32, 1065–1076. doi: 10.1093/eurheartj/ehr105
-
(2011)
Eur. Heart J.
, vol.32
, pp. 1065-1076
-
-
Villard, E.1
Perret, C.2
Gary, F.3
Proust, C.4
Dilanian, G.5
Hengstenberg, C.6
-
178
-
-
65249087364
-
The anti-apoptotic activity of BAG3 is restricted by caspases and the proteasome
-
Virador, V. M., Davidson, B., Czechowicz, J., Mai, A., Kassis, J., and Kohn, E. C. (2009). The anti-apoptotic activity of BAG3 is restricted by caspases and the proteasome. PLoS ONE 4:e5136. doi: 10.1371/journal.pone.0005136
-
(2009)
Plos ONE
, vol.4
-
-
Virador, V.M.1
Davidson, B.2
Czechowicz, J.3
Mai, A.4
Kassis, J.5
Kohn, E.C.6
-
179
-
-
0032867676
-
The 26S proteasome: A molecular machine designed for controlled proteolysis
-
Voges, D., Zwickl, P., and Baumeister, W. (1999). The 26S proteasome: a molecular machine designed for controlled proteolysis. Annu. Rev. Biochem. 68, 1015– 1068. doi: 10.1146/annurev.biochem.68.1.1015
-
(1999)
Annu. Rev. Biochem.
, vol.68
-
-
Voges, D.1
Zwickl, P.2
Baumeister, W.3
-
180
-
-
46849116411
-
Structural and functional diversities between members of the human HSPB, HSPH, HSPA, and DNAJ chaperone families
-
Vos, M. J., Hageman, J., Carra, S., and Kampinga, H. H. (2008). Structural and functional diversities between members of the human HSPB, HSPH, HSPA, and DNAJ chaperone families. Biochemistry 47, 7001–7011. doi: 10.1021/bi800639z
-
(2008)
Biochemistry
, vol.47
, pp. 7001-7011
-
-
Vos, M.J.1
Hageman, J.2
Carra, S.3
Kampinga, H.H.4
-
181
-
-
33644843542
-
A genomewide analysis of genes for the heat shock protein 70 chaperone system in the ascidian Ciona intestinalis
-
Wada, S., Hamada, M., and Satoh, N. (2006). A genomewide analysis of genes for the heat shock protein 70 chaperone system in the ascidian Ciona intestinalis. Cell Stress Chaperones 11, 23–33.
-
(2006)
Cell Stress Chaperones
, vol.11
, pp. 23-33
-
-
Wada, S.1
Hamada, M.2
Satoh, N.3
-
182
-
-
36249000085
-
Transcriptional upregulation of BAG3 upon proteasome inhibition
-
Wang, H. Q., Liu, H. M., Zhang, H. Y., Guan, Y., and Du, Z. X. (2008). Transcriptional upregulation of BAG3 upon proteasome inhibition. Biochem. Biophys. Res. Commun. 365, 381–385. doi: 10.1016/j.bbrc.2007.11.001
-
(2008)
Biochem. Biophys. Res. Commun.
, vol.365
, pp. 381-385
-
-
Wang, H.Q.1
Liu, H.M.2
Zhang, H.Y.3
Guan, Y.4
Du, Z.X.5
-
183
-
-
84947605462
-
Autophagy signal transduction by ATG proteins: From hierarchies to networks
-
Wesselborg, S., and Stork, B. (2015). Autophagy signal transduction by ATG proteins: from hierarchies to networks. Cell Mol. Life. Sci. 72, 4721–4757. doi: 10.1007/s00018-015-2034-8
-
(2015)
Cell Mol. Life. Sci.
, vol.72
, pp. 4721-4757
-
-
Wesselborg, S.1
Stork, B.2
-
184
-
-
84896817592
-
BAG3 regulates epithelial-mesenchymal transition and angiogenesis in human hepatocellular carcinoma
-
Xiao, H., Cheng, S., Tong, R., Lv, Z., Ding, C., Du, C., et al. (2014). BAG3 regulates epithelial-mesenchymal transition and angiogenesis in human hepatocellular carcinoma. Lab. Invest. 94, 252–261. doi: 10.1038/labinvest.2013.151
-
(2014)
Lab. Invest
, vol.94
, pp. 252-261
-
-
Xiao, H.1
Cheng, S.2
Tong, R.3
Lv, Z.4
Ding, C.5
Du, C.6
-
185
-
-
63049125531
-
Quantitative proteomics reveals the function of unconventional ubiquitin chains in proteasomal degradation
-
Xu, P., Duong, D. M., Seyfried, N. T., Cheng, D., Xie, Y., Robert, J., et al. (2009). Quantitative proteomics reveals the function of unconventional ubiquitin chains in proteasomal degradation. Cell 137, 133–145. doi: 10.1016/j.cell.2009.01.041
-
(2009)
Cell
, vol.137
, pp. 133-145
-
-
Xu, P.1
Duong, D.M.2
Seyfried, N.T.3
Cheng, D.4
Xie, Y.5
Robert, J.6
-
186
-
-
84885444527
-
14-3-3 protein targets misfolded chaperone-associated proteins to aggresomes
-
Xu, Z., Graham, K., Foote, M., Liang, F., Rizkallah, R., Hurt, M., et al. (2013). 14-3-3 protein targets misfolded chaperone-associated proteins to aggresomes. J. Cell Sci. 126(Pt 18), 4173–4186. doi: 10.1242/jcs.126102
-
(2013)
J. Cell Sci
, vol.126
, pp. 4173-4186
-
-
Xu, Z.1
Graham, K.2
Foote, M.3
Liang, F.4
Rizkallah, R.5
Hurt, M.6
-
187
-
-
84910626377
-
Identification of extracellular signal-regulated kinase 1 (ERK1) direct substrates using stable isotope labeled kinase assay-linked phosphoproteomics
-
Xue, L., Wang, P., Cao, P., Zhu, J. K., and Tao, W. A. (2014). Identification of extracellular signal-regulated kinase 1 (ERK1) direct substrates using stable isotope labeled kinase assay-linked phosphoproteomics. Mol. Cell. Proteomics 13, 3199–3210. doi: 10.1074/mcp.O114.038588
-
(2014)
Mol. Cell. Proteomics
, vol.13
, pp. 3199-3210
-
-
Xue, L.1
Wang, P.2
Cao, P.3
Zhu, J.K.4
Tao, W.A.5
-
188
-
-
70350461507
-
Building ubiquitin chains: E2 enzymes at work
-
Ye, Y., and Rape, M. (2009). Building ubiquitin chains: E2 enzymes at work. Nat. Rev. Mol. Cell Biol. 10, 755–764. doi: 10.1038/nrm2780
-
(2009)
Nat. Rev. Mol. Cell Biol.
, vol.10
, pp. 755-764
-
-
Ye, Y.1
Rape, M.2
-
189
-
-
57349143456
-
Bis deficiency results in early lethality with metabolic deterioration and involution of spleen and thymus
-
Youn, D. Y., Lee, D. H., Lim, M. H., Yoon, J. S., Lim, J. H., Jung, S. E., et al. (2008). Bis deficiency results in early lethality with metabolic deterioration and involution of spleen and thymus. Am. J. Physiol. Endocrinol. Metab. 295, E1349–E1357. doi: 10.1152/ajpendo.90704.2008
-
(2008)
Am. J. Physiol. Endocrinol. Metab
, vol.295
, pp. E1349-E1357
-
-
Youn, D.Y.1
Lee, D.H.2
Lim, M.H.3
Yoon, J.S.4
Lim, J.H.5
Jung, S.E.6
-
190
-
-
77950600645
-
Mechanisms of the Hsp70 chaperone system
-
Young, J. C. (2010). Mechanisms of the Hsp70 chaperone system. Biochem. Cell Biol. 88, 291–300. doi: 10.1139/o09-175
-
(2010)
Biochem. Cell Biol
, vol.88
, pp. 291-300
-
-
Young, J.C.1
-
191
-
-
80052830376
-
Chaperone-mediated hierarchical control in targeting misfolded proteins to aggresomes
-
Zhang, X., and Qian, S. B. (2011). Chaperone-mediated hierarchical control in targeting misfolded proteins to aggresomes. Mol. Biol. Cell 22, 3277–3288. doi: 10.1091/mbc.E11-05-0388
-
(2011)
Mol. Biol. Cell
, vol.22
, pp. 3277-3288
-
-
Zhang, X.1
Qian, S.B.2
-
192
-
-
80455122653
-
14-3-3 proteins as potential therapeutic targets
-
Zhao, J., Meyerkord, C. L., Du, Y., Khuri, F. R., and Fu, H. (2011). 14-3-3 proteins as potential therapeutic targets. Semin. Cell Dev. Biol. 22, 705–712. doi: 10.1016/j.semcdb.2011.09.012
-
(2011)
Semin. Cell Dev. Biol.
, vol.22
, pp. 705-712
-
-
Zhao, J.1
Meyerkord, C.L.2
Du, Y.3
Khuri, F.R.4
Fu, H.5
-
193
-
-
84894315232
-
Overexpressed BAG3 is a potential therapeutic target in chronic lymphocytic leukemia
-
Zhu, H., Wu, W., Fu, Y., Shen, W., Miao, K., Hong, M., et al. (2014). Overexpressed BAG3 is a potential therapeutic target in chronic lymphocytic leukemia. Ann. Hematol. 93, 425–435. doi: 10.1007/s00277-013-1883-1
-
(2014)
Ann. Hematol.
, vol.93
, pp. 425-435
-
-
Zhu, H.1
Wu, W.2
Fu, Y.3
Shen, W.4
Miao, K.5
Hong, M.6
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