메뉴 건너뛰기




Volumn 93, Issue 3, 2014, Pages 425-435

Overexpressed BAG3 is a potential therapeutic target in chronic lymphocytic leukemia

Author keywords

Apoptosis; BAG3; Cell migration; Chronic lymphocytic leukemia

Indexed keywords

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADULT; AGED; AGED, 80 AND OVER; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL MOVEMENT; FEMALE; FOLLOW-UP STUDIES; GENE SILENCING; HUMANS; LEUKEMIA, LYMPHOCYTIC, CHRONIC, B-CELL; MALE; MIDDLE AGED; NEOPLASM PROTEINS; NEOPLASM STAGING; PROGNOSIS; SURVIVAL ANALYSIS; TUMOR CELLS, CULTURED; TUMOR MARKERS, BIOLOGICAL; UP-REGULATION;

EID: 84894315232     PISSN: 09395555     EISSN: 14320584     Source Type: Journal    
DOI: 10.1007/s00277-013-1883-1     Document Type: Article
Times cited : (24)

References (45)
  • 1
    • 13844307760 scopus 로고    scopus 로고
    • Chronic lymphocytic leukemia
    • 1:CAS:528:DC%2BD2MXhsFCiu74%3D 10.1056/NEJMra041720 15728813
    • Chiorazzi N, Rai KR, Ferrarini M (2005) Chronic lymphocytic leukemia. N Engl J Med 352:804-815
    • (2005) N Engl J Med , vol.352 , pp. 804-815
    • Chiorazzi, N.1    Rai, K.R.2    Ferrarini, M.3
  • 2
    • 53449090161 scopus 로고    scopus 로고
    • Combined molecular biological and molecular cytogenetic analysis of genomic changes in 146 patients with B-cell chronic lymphocytic leukemia
    • 1:STN:280:DC%2BD1cvosFGrsQ%3D%3D 18665750
    • Berkova A, Pavlistova L, Babicka L et al (2008) Combined molecular biological and molecular cytogenetic analysis of genomic changes in 146 patients with B-cell chronic lymphocytic leukemia. Neoplasma 55:400-408
    • (2008) Neoplasma , vol.55 , pp. 400-408
    • Berkova, A.1    Pavlistova, L.2    Babicka, L.3
  • 3
    • 85027920745 scopus 로고    scopus 로고
    • Prognostic factors in chronic lymphocytic leukemia - What do we need to know?
    • 1:CAS:528:DC%2BC3cXhsF2mur3P 10.1038/nrclinonc.2010.167 20956983
    • Cramer P, Hallek M (2011) Prognostic factors in chronic lymphocytic leukemia - what do we need to know? Nat Rev Clin Oncol 8:38-47
    • (2011) Nat Rev Clin Oncol , vol.8 , pp. 38-47
    • Cramer, P.1    Hallek, M.2
  • 4
    • 77950655773 scopus 로고    scopus 로고
    • The Bcl-2 family as a rational target for the treatment of B-cell chronic lymphocytic leukaemia
    • 1:CAS:528:DC%2BC3cXksFOhsr4%3D 10.2174/092986710790712165 20156175
    • Capitani N, Baldari CT (2010) The Bcl-2 family as a rational target for the treatment of B-cell chronic lymphocytic leukaemia. Curr Med Chem 17:801-811
    • (2010) Curr Med Chem , vol.17 , pp. 801-811
    • Capitani, N.1    Baldari, C.T.2
  • 5
    • 0028847915 scopus 로고
    • Cloning and functional analysis of BAG-1: A novel Bcl-2-binding protein with anti-cell death activity
    • 1:CAS:528:DyaK2MXjtlGns74%3D 10.1016/0092-8674(95)90410-7 7834747
    • Takayama S, Sato T, Krajewski S et al (1995) Cloning and functional analysis of BAG-1: a novel Bcl-2-binding protein with anti-cell death activity. Cell 80:279-284
    • (1995) Cell , vol.80 , pp. 279-284
    • Takayama, S.1    Sato, T.2    Krajewski, S.3
  • 6
    • 0037114358 scopus 로고    scopus 로고
    • What's in the 'BAG'? - A functional domain analysis of the BAG-family proteins
    • 1:CAS:528:DC%2BD38Xot1Wqt7k%3D 10.1016/S0304-3835(02)00456-1 12406544
    • Doong H, Vrailas A, Kohn EC (2002) What's in the 'BAG'? - a functional domain analysis of the BAG-family proteins. Cancer Lett 188:25-32
    • (2002) Cancer Lett , vol.188 , pp. 25-32
    • Doong, H.1    Vrailas, A.2    Kohn, E.C.3
  • 7
    • 0034790768 scopus 로고    scopus 로고
    • Molecular chaperone targeting and regulation by BAG family proteins
    • 1:CAS:528:DC%2BD3MXnslart7c%3D 10.1038/ncb1001-e237 11584289
    • Takayama S, Reed JC (2001) Molecular chaperone targeting and regulation by BAG family proteins. Nat Cell Biol 3:E237-E241
    • (2001) Nat Cell Biol , vol.3
    • Takayama, S.1    Reed, J.C.2
  • 8
    • 33747376303 scopus 로고    scopus 로고
    • CAIR-1/BAG-3 modulates cell adhesion and migration by downregulating activity of focal adhesion proteins
    • 1:CAS:528:DC%2BD28XovVWqu7g%3D 10.1016/j.yexcr.2006.05.023 16859681
    • Kassis JN, Guancial EA, Doong H, Virador V, Kohn EC (2006) CAIR-1/BAG-3 modulates cell adhesion and migration by downregulating activity of focal adhesion proteins. Exp Cell Res 312:2962-2971
    • (2006) Exp Cell Res , vol.312 , pp. 2962-2971
    • Kassis, J.N.1    Guancial, E.A.2    Doong, H.3    Virador, V.4    Kohn, E.C.5
  • 9
    • 0033534588 scopus 로고    scopus 로고
    • An evolutionarily conserved family of Hsp70/Hsc70 molecular chaperone regulators
    • 1:CAS:528:DyaK1MXmtFGmtg%3D%3D 10.1074/jbc.274.2.781 9873016
    • Takayama S, Xie Z, Reed JC (1999) An evolutionarily conserved family of Hsp70/Hsc70 molecular chaperone regulators. J Biol Chem 274:781-786
    • (1999) J Biol Chem , vol.274 , pp. 781-786
    • Takayama, S.1    Xie, Z.2    Reed, J.C.3
  • 10
    • 10744228410 scopus 로고    scopus 로고
    • BAG3 protein regulates stress-induced apoptosis in normal and neoplastic leukocytes
    • 1:CAS:528:DC%2BD2cXlt1ahug%3D%3D 10.1038/sj.leu.2403219 14628070
    • Bonelli P, Petrella A, Rosati A et al (2004) BAG3 protein regulates stress-induced apoptosis in normal and neoplastic leukocytes. Leukemia 18:358-360
    • (2004) Leukemia , vol.18 , pp. 358-360
    • Bonelli, P.1    Petrella, A.2    Rosati, A.3
  • 11
    • 33947542628 scopus 로고    scopus 로고
    • The antiapoptotic protein BAG3 is expressed in thyroid carcinomas and modulates apoptosis mediated by tumor necrosis factor-related apoptosis-inducing ligand
    • 1:CAS:528:DC%2BD2sXjtlGmsLg%3D 10.1210/jc.2006-1712 17164298
    • Chiappetta G, Ammirante M, Basile A et al (2007) The antiapoptotic protein BAG3 is expressed in thyroid carcinomas and modulates apoptosis mediated by tumor necrosis factor-related apoptosis-inducing ligand. J Clin Endocrinol Metab 92:1159-1163
    • (2007) J Clin Endocrinol Metab , vol.92 , pp. 1159-1163
    • Chiappetta, G.1    Ammirante, M.2    Basile, A.3
  • 12
    • 0035902997 scopus 로고    scopus 로고
    • The anti-apoptotic protein BAG-3 is overexpressed in pancreatic cancer and induced by heat stress in pancreatic cancer cell lines
    • 1:CAS:528:DC%2BD3MXmtFWit78%3D 10.1016/S0014-5793(01)02728-4 11513873
    • Liao Q, Ozawa F, Friess H et al (2001) The anti-apoptotic protein BAG-3 is overexpressed in pancreatic cancer and induced by heat stress in pancreatic cancer cell lines. FEBS Lett 503:151-157
    • (2001) FEBS Lett , vol.503 , pp. 151-157
    • Liao, Q.1    Ozawa, F.2    Friess, H.3
  • 13
    • 78049509833 scopus 로고    scopus 로고
    • BAG3 protein delocalisation in prostate carcinoma
    • 1:CAS:528:DC%2BC3cXht1elt7bJ 10.1007/s13277-010-0055-3 20535599
    • Staibano S, Mascolo M, Di Benedetto M et al (2010) BAG3 protein delocalisation in prostate carcinoma. Tumour Biol 31:461-469
    • (2010) Tumour Biol , vol.31 , pp. 461-469
    • Staibano, S.1    Mascolo, M.2    Di Benedetto, M.3
  • 14
    • 35949000838 scopus 로고    scopus 로고
    • BAG3 regulates motility and adhesion of epithelial cancer cells
    • 1:CAS:528:DC%2BD2sXht1erur%2FL 10.1158/0008-5472.CAN-07-0618 17974966
    • Iwasaki M, Homma S, Hishiya A et al (2007) BAG3 regulates motility and adhesion of epithelial cancer cells. Cancer Res 67:10252-10259
    • (2007) Cancer Res , vol.67 , pp. 10252-10259
    • Iwasaki, M.1    Homma, S.2    Hishiya, A.3
  • 15
    • 79951857812 scopus 로고    scopus 로고
    • BAG3 (BCL2-associated athanogene 3) interacts with MMP-2 to positively regulate invasion by ovarian carcinoma cells
    • 1:CAS:528:DC%2BC3MXisFGms78%3D 10.1016/j.canlet.2011.01.019 21316839
    • Suzuki M, Iwasaki M, Sugio A et al (2011) BAG3 (BCL2-associated athanogene 3) interacts with MMP-2 to positively regulate invasion by ovarian carcinoma cells. Cancer Lett 303:65-71
    • (2011) Cancer Lett , vol.303 , pp. 65-71
    • Suzuki, M.1    Iwasaki, M.2    Sugio, A.3
  • 16
    • 0037621432 scopus 로고    scopus 로고
    • BAG3 protein controls B-chronic lymphocytic leukaemia cell apoptosis
    • 1:CAS:528:DC%2BD3sXivFGhtL0%3D 10.1038/sj.cdd.4401167 12700638
    • Romano MF, Festa M, Pagliuca G et al (2003) BAG3 protein controls B-chronic lymphocytic leukaemia cell apoptosis. Cell Death Differ 10:383-385
    • (2003) Cell Death Differ , vol.10 , pp. 383-385
    • Romano, M.F.1    Festa, M.2    Pagliuca, G.3
  • 17
    • 1542682413 scopus 로고    scopus 로고
    • BAG3 protein regulates cell survival in childhood acute lymphoblastic leukemia cells
    • 1:CAS:528:DC%2BD2cXhtVOitbc%3D 10.4161/cbt.2.5.524 14614315
    • Romano MF, Festa M, Petrella A et al (2003) BAG3 protein regulates cell survival in childhood acute lymphoblastic leukemia cells. Cancer Biol Ther 2:508-510
    • (2003) Cancer Biol Ther , vol.2 , pp. 508-510
    • Romano, M.F.1    Festa, M.2    Petrella, A.3
  • 18
    • 58149494120 scopus 로고    scopus 로고
    • BAG3 gene silencing sensitizes leukemic cells to Bortezomib-induced apoptosis
    • 1:CAS:528:DC%2BD1MXotlKmug%3D%3D 10.1016/j.febslet.2008.12.032 19111544
    • Liu P, Xu B, Li J, Lu H (2009) BAG3 gene silencing sensitizes leukemic cells to Bortezomib-induced apoptosis. FEBS Lett 583:401-406
    • (2009) FEBS Lett , vol.583 , pp. 401-406
    • Liu, P.1    Xu, B.2    Li, J.3    Lu, H.4
  • 19
    • 36249000085 scopus 로고    scopus 로고
    • Transcriptional upregulation of BAG3 upon proteasome inhibition
    • 1:CAS:528:DC%2BD2sXhtlCrsLjI 10.1016/j.bbrc.2007.11.001 17996194
    • Wang HQ, Liu HM, Zhang HY, Guan Y, Du ZX (2008) Transcriptional upregulation of BAG3 upon proteasome inhibition. Biochem Biophys Res Commun 365:381-385
    • (2008) Biochem Biophys Res Commun , vol.365 , pp. 381-385
    • Wang, H.Q.1    Liu, H.M.2    Zhang, H.Y.3    Guan, Y.4    Du, Z.X.5
  • 20
    • 47249099397 scopus 로고    scopus 로고
    • Altered gene expression in busulfan-resistant human myeloid leukemia
    • 1:CAS:528:DC%2BD1cXoslWmuro%3D 10.1016/j.leukres.2008.01.016 2633244 18339423
    • Valdez BC, Murray D, Ramdas L et al (2008) Altered gene expression in busulfan-resistant human myeloid leukemia. Leuk Res 32:1684-1697
    • (2008) Leuk Res , vol.32 , pp. 1684-1697
    • Valdez, B.C.1    Murray, D.2    Ramdas, L.3
  • 21
    • 80053314135 scopus 로고    scopus 로고
    • Bag3 gene expression in chronic lymphocytic leukemia and its association with patients' prognosis
    • 1:CAS:528:DC%2BC3cXhsFCmt7nN 20723284
    • Chen HY, Liu P, Sun M et al (2010) Bag3 gene expression in chronic lymphocytic leukemia and its association with patients' prognosis. Zhongguo Shi Yan Xue Ye Xue Za Zhi 18:838-842
    • (2010) Zhongguo Shi Yan Xue Ye Xue Za Zhi , vol.18 , pp. 838-842
    • Chen, H.Y.1    Liu, P.2    Sun, M.3
  • 22
    • 84863283179 scopus 로고    scopus 로고
    • BAG3: A new therapeutic target of human cancers?
    • 1:CAS:528:DC%2BC38XivFyjs74%3D 22237703
    • Zhu H, Liu P, Li J (2012) BAG3: a new therapeutic target of human cancers? Histol Histopathol 27:257-261
    • (2012) Histol Histopathol , vol.27 , pp. 257-261
    • Zhu, H.1    Liu, P.2    Li, J.3
  • 23
    • 18744366077 scopus 로고    scopus 로고
    • World Medical Association Declaration of Helsinki: Ethical principles for medical research involving human subjects
    • Anonymous
    • Anonymous (2004) World Medical Association Declaration of Helsinki: ethical principles for medical research involving human subjects. J Int Bioethique 15:124-129
    • (2004) J Int Bioethique , vol.15 , pp. 124-129
  • 24
    • 45149100665 scopus 로고    scopus 로고
    • Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: A report from the International Workshop on Chronic Lymphocytic Leukemia updating the National Cancer Institute-Working Group 1996 guidelines
    • 1:CAS:528:DC%2BD1cXnsVOktrk%3D 10.1182/blood-2007-06-093906 18216293
    • Hallek M, Cheson BD, Catovsky D et al (2008) Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: a report from the International Workshop on Chronic Lymphocytic Leukemia updating the National Cancer Institute-Working Group 1996 guidelines. Blood 111:5446-5456
    • (2008) Blood , vol.111 , pp. 5446-5456
    • Hallek, M.1    Cheson, B.D.2    Catovsky, D.3
  • 25
    • 0036335916 scopus 로고    scopus 로고
    • Results of first salvage therapy for patients refractory to a fludarabine regimen in chronic lymphocytic leukemia
    • 1:CAS:528:DC%2BD38XntVKjsb4%3D 10.1080/1042819021000006547 12685828
    • Keating MJ, O'Brien S, Kontoyiannis D et al (2002) Results of first salvage therapy for patients refractory to a fludarabine regimen in chronic lymphocytic leukemia. Leuk Lymphoma 43:1755-1762
    • (2002) Leuk Lymphoma , vol.43 , pp. 1755-1762
    • Keating, M.J.1    O'Brien, S.2    Kontoyiannis, D.3
  • 26
    • 41949084748 scopus 로고    scopus 로고
    • Prognostic significance of ATM and TP53 deletions in Chinese patients with chronic lymphocytic leukemia
    • 1:CAS:528:DC%2BD1cXkvFWkt7Y%3D 10.1016/j.leukres.2007.10.009 18035414
    • Xu W, Li JY, Wu YJ et al (2008) Prognostic significance of ATM and TP53 deletions in Chinese patients with chronic lymphocytic leukemia. Leuk Res 32:1071-1077
    • (2008) Leuk Res , vol.32 , pp. 1071-1077
    • Xu, W.1    Li, J.Y.2    Wu, Y.J.3
  • 27
    • 79956071061 scopus 로고    scopus 로고
    • The prognostic significance of TP53 mutations in Chinese patients with chronic lymphocytic leukemia is independent of del(17p13)
    • 1:CAS:528:DC%2BC3MXlslahtLg%3D 10.1007/s00277-010-1125-8 21113594
    • Dong HJ, Zhou LT, Zhu DX et al (2011) The prognostic significance of TP53 mutations in Chinese patients with chronic lymphocytic leukemia is independent of del(17p13). Ann Hematol 90:709-717
    • (2011) Ann Hematol , vol.90 , pp. 709-717
    • Dong, H.J.1    Zhou, L.T.2    Zhu, D.X.3
  • 28
    • 77952952903 scopus 로고    scopus 로고
    • The role of Bcl-2 family proteins in chronic lymphocytic leukaemia
    • 1:CAS:528:DC%2BC3cXmsVSls7s%3D 10.1016/j.leukres.2010.03.011 20359747
    • Buggins AG, Pepper CJ (2010) The role of Bcl-2 family proteins in chronic lymphocytic leukaemia. Leuk Res 34:837-842
    • (2010) Leuk Res , vol.34 , pp. 837-842
    • Buggins, A.G.1    Pepper, C.J.2
  • 29
    • 31344459761 scopus 로고    scopus 로고
    • Bis induces growth inhibition and differentiation of HL-60 cells via up-regulation of p27
    • 1:CAS:528:DC%2BD28XjvFGnsQ%3D%3D 10.1038/emm.2005.76 16391524
    • Seo YJ, Jeon MH, Lee JH et al (2005) Bis induces growth inhibition and differentiation of HL-60 cells via up-regulation of p27. Exp Mol Med 37:624-630
    • (2005) Exp Mol Med , vol.37 , pp. 624-630
    • Seo, Y.J.1    Jeon, M.H.2    Lee, J.H.3
  • 30
    • 64849101121 scopus 로고    scopus 로고
    • Identification of a Btk-BAG3 complex induced by oxidative stress
    • 1:CAS:528:DC%2BD1MXks1Sit7c%3D 10.1038/leu.2009.23 19212330
    • Rosati A, Di Salle E, Luberto L et al (2009) Identification of a Btk-BAG3 complex induced by oxidative stress. Leukemia 23:823-824
    • (2009) Leukemia , vol.23 , pp. 823-824
    • Rosati, A.1    Di Salle, E.2    Luberto, L.3
  • 31
    • 77954589714 scopus 로고    scopus 로고
    • WT1 protein is a transcriptional activator of the antiapoptotic bag3 gene
    • 1:STN:280:DC%2BC3cvotlCjsg%3D%3D 10.1038/leu.2010.68 20410921
    • Cesaro E, Montano G, Rosati A et al (2010) WT1 protein is a transcriptional activator of the antiapoptotic bag3 gene. Leukemia 24:1204-1206
    • (2010) Leukemia , vol.24 , pp. 1204-1206
    • Cesaro, E.1    Montano, G.2    Rosati, A.3
  • 32
    • 0037103212 scopus 로고    scopus 로고
    • V(H) mutation status, CD38 expression level, genomic aberrations, and survival in chronic lymphocytic leukemia
    • 1:CAS:528:DC%2BD38Xmt12iur0%3D 12149225
    • Krober A, Seiler T, Benner A et al (2002) V(H) mutation status, CD38 expression level, genomic aberrations, and survival in chronic lymphocytic leukemia. Blood 100:1410-1416
    • (2002) Blood , vol.100 , pp. 1410-1416
    • Krober, A.1    Seiler, T.2    Benner, A.3
  • 33
    • 0035679122 scopus 로고    scopus 로고
    • Analysis of clonal B-cell CD38 and immunoglobulin variable region sequence status in relation to clinical outcome for B-chronic lymphocytic leukaemia
    • 1:CAS:528:DC%2BD38XltlCksg%3D%3D 10.1046/j.1365-2141.2001.03149.x 11843819
    • Jelinek DF, Tschumper RC, Geyer SM et al (2001) Analysis of clonal B-cell CD38 and immunoglobulin variable region sequence status in relation to clinical outcome for B-chronic lymphocytic leukaemia. Br J Haematol 115:854-861
    • (2001) Br J Haematol , vol.115 , pp. 854-861
    • Jelinek, D.F.1    Tschumper, R.C.2    Geyer, S.M.3
  • 34
    • 33751102626 scopus 로고    scopus 로고
    • CD38 expression level and pattern of expression remains a reliable and robust marker of progressive disease in chronic lymphocytic leukemia
    • 1:CAS:528:DC%2BD2sXlslGlsQ%3D%3D 10.1080/10428190600947727 17107912
    • Hayat A, O'Brien D, O'Rourke P et al (2006) CD38 expression level and pattern of expression remains a reliable and robust marker of progressive disease in chronic lymphocytic leukemia. Leuk Lymphoma 47:2371-2379
    • (2006) Leuk Lymphoma , vol.47 , pp. 2371-2379
    • Hayat, A.1    O'Brien, D.2    O'Rourke, P.3
  • 35
    • 0035803371 scopus 로고    scopus 로고
    • Relation of gene expression phenotype to immunoglobulin mutation genotype in B cell chronic lymphocytic leukemia
    • 1:CAS:528:DC%2BD3MXovVOktL4%3D 10.1084/jem.194.11.1639 2193523 11733578
    • Rosenwald A, Alizadeh AA, Widhopf G et al (2001) Relation of gene expression phenotype to immunoglobulin mutation genotype in B cell chronic lymphocytic leukemia. J Exp Med 194:1639-1647
    • (2001) J Exp Med , vol.194 , pp. 1639-1647
    • Rosenwald, A.1    Alizadeh, A.A.2    Widhopf, G.3
  • 36
    • 10744222814 scopus 로고    scopus 로고
    • ZAP-70 expression identifies a chronic lymphocytic leukemia subtype with unmutated immunoglobulin genes, inferior clinical outcome, and distinct gene expression profile
    • 1:CAS:528:DC%2BD3sXkslCjsb4%3D 10.1182/blood-2002-10-3306 12595313
    • Wiestner A, Rosenwald A, Barry TS et al (2003) ZAP-70 expression identifies a chronic lymphocytic leukemia subtype with unmutated immunoglobulin genes, inferior clinical outcome, and distinct gene expression profile. Blood 101:4944-4951
    • (2003) Blood , vol.101 , pp. 4944-4951
    • Wiestner, A.1    Rosenwald, A.2    Barry, T.S.3
  • 37
    • 0028987180 scopus 로고
    • P53 gene deletion predicts for poor survival and non-response to therapy with purine analogs in chronic B-cell leukemias
    • 1:STN:280:DyaK2M7psFahtA%3D%3D 7888675
    • Dohner H, Fischer K, Bentz M et al (1995) p53 gene deletion predicts for poor survival and non-response to therapy with purine analogs in chronic B-cell leukemias. Blood 85:1580-1589
    • (1995) Blood , vol.85 , pp. 1580-1589
    • Dohner, H.1    Fischer, K.2    Bentz, M.3
  • 38
    • 0037103272 scopus 로고    scopus 로고
    • Relationship between p53 dysfunction, CD38 expression, and IgV(H) mutation in chronic lymphocytic leukemia
    • 1:CAS:528:DC%2BD38Xmt12iurw%3D 10.1182/blood-2001-11-0066 12149224
    • Lin K, Sherrington PD, Dennis M et al (2002) Relationship between p53 dysfunction, CD38 expression, and IgV(H) mutation in chronic lymphocytic leukemia. Blood 100:1404-1409
    • (2002) Blood , vol.100 , pp. 1404-1409
    • Lin, K.1    Sherrington, P.D.2    Dennis, M.3
  • 39
    • 0033523874 scopus 로고    scopus 로고
    • Bis, a Bcl-2-binding protein that synergizes with Bcl-2 in preventing cell death
    • 1:CAS:528:DyaK1MXnslKrsb8%3D 10.1038/sj.onc.1203043 10597216
    • Lee JH, Takahashi T, Yasuhara N et al (1999) Bis, a Bcl-2-binding protein that synergizes with Bcl-2 in preventing cell death. Oncogene 18:6183-6190
    • (1999) Oncogene , vol.18 , pp. 6183-6190
    • Lee, J.H.1    Takahashi, T.2    Yasuhara, N.3
  • 40
    • 66149118221 scopus 로고    scopus 로고
    • HSF1-mediated BAG3 expression attenuates apoptosis in 4-hydroxynonenal-treated colon cancer cells via stabilization of anti-apoptotic Bcl-2 proteins
    • 1:CAS:528:DC%2BD1MXjs1ymsr8%3D 10.1074/jbc.M808656200 19179333
    • Jacobs AT, Marnett LJ (2009) HSF1-mediated BAG3 expression attenuates apoptosis in 4-hydroxynonenal-treated colon cancer cells via stabilization of anti-apoptotic Bcl-2 proteins. J Biol Chem 284:9176-9183
    • (2009) J Biol Chem , vol.284 , pp. 9176-9183
    • Jacobs, A.T.1    Marnett, L.J.2
  • 41
    • 77952112425 scopus 로고    scopus 로고
    • IKKγ protein is a target of BAG3 regulatory activity in human tumor growth
    • 1:CAS:528:DC%2BC3cXlsFWhtr8%3D 10.1073/pnas.0907696107 20368414
    • Ammirante M, Rosati A, Arra C et al (2010) IKKγ protein is a target of BAG3 regulatory activity in human tumor growth. Proc Natl Acad Sci USA 107:7497-7502
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 7497-7502
    • Ammirante, M.1    Rosati, A.2    Arra, C.3
  • 42
    • 41149104785 scopus 로고    scopus 로고
    • Caspase-dependent cleavage of BAG3 in proteasome inhibitors-induced apoptosis in thyroid cancer cells
    • 1:CAS:528:DC%2BD1cXktFekt78%3D 10.1016/j.bbrc.2008.02.112 18325327
    • Du ZX, Meng X, Zhang HY, Guan Y, Wang HQ (2008) Caspase-dependent cleavage of BAG3 in proteasome inhibitors-induced apoptosis in thyroid cancer cells. Biochem Biophys Res Commun 369:894-898
    • (2008) Biochem Biophys Res Commun , vol.369 , pp. 894-898
    • Du, Z.X.1    Meng, X.2    Zhang, H.Y.3    Guan, Y.4    Wang, H.Q.5
  • 43
    • 70849086745 scopus 로고    scopus 로고
    • Inhibition of the JNK signalling pathway enhances proteasome inhibitor-induced apoptosis of kidney cancer cells by suppression of BAG3 expression
    • 1:CAS:528:DC%2BD1MXhsVSksL%2FI 10.1111/j.1476-5381.2009.00455.x 19681889
    • Wang HQ, Liu BQ, Gao YY et al (2009) Inhibition of the JNK signalling pathway enhances proteasome inhibitor-induced apoptosis of kidney cancer cells by suppression of BAG3 expression. Br J Pharmacol 158:1405-1412
    • (2009) Br J Pharmacol , vol.158 , pp. 1405-1412
    • Wang, H.Q.1    Liu, B.Q.2    Gao, Y.Y.3
  • 44
    • 80053900118 scopus 로고    scopus 로고
    • BAG1: The guardian of anti-apoptotic proteins in acute myeloid leukemia
    • 1:CAS:528:DC%2BC3MXhtl2mtb%2FI 10.1371/journal.pone.0026097 3189928 22016818
    • Aveic S, Pigazzi M, Basso G (2011) BAG1: the guardian of anti-apoptotic proteins in acute myeloid leukemia. PLoS One 6:e26097
    • (2011) PLoS One , vol.6 , pp. 26097
    • Aveic, S.1    Pigazzi, M.2    Basso, G.3
  • 45
    • 77956940128 scopus 로고    scopus 로고
    • BAG3 directly associates with guanine nucleotide exchange factor of Rap1, PDZGEF2, and regulates cell adhesion
    • 1:CAS:528:DC%2BC3cXht1WltrnI 10.1016/j.bbrc.2010.08.092 2954587 20800573
    • Iwasaki M, Tanaka R, Hishiya A et al (2010) BAG3 directly associates with guanine nucleotide exchange factor of Rap1, PDZGEF2, and regulates cell adhesion. Biochem Biophys Res Commun 400:413-418
    • (2010) Biochem Biophys Res Commun , vol.400 , pp. 413-418
    • Iwasaki, M.1    Tanaka, R.2    Hishiya, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.