-
1
-
-
20044366163
-
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
-
Stupp R, Mason WP, van den Bent MJ, Weller M, Fisher B, Taphoorn MJ, Belanger K, Brandes AA, Marosi C, Bogdahn U, Curschmann J, Janzer RC, Ludwin SK, et al. Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med. 2005; 352:987-996
-
(2005)
N Engl J Med
, vol.352
, pp. 987-996
-
-
Stupp, R.1
Mason, W.P.2
van den Bent, M.J.3
Weller, M.4
Fisher, B.5
Taphoorn, M.J.6
Belanger, K.7
Brandes, A.A.8
Marosi, C.9
Bogdahn, U.10
Curschmann, J.11
Janzer, R.C.12
Ludwin, S.K.13
-
2
-
-
84933530651
-
Cancer stem cells in glioblastoma
-
Lathia JD, Mack SC, Mulkearns-Hubert EE, Valentim CL, Rich JN. Cancer stem cells in glioblastoma. Genes Dev. 2015; 29:1203-1217
-
(2015)
Genes Dev
, vol.29
, pp. 1203-1217
-
-
Lathia, J.D.1
Mack, S.C.2
Mulkearns-Hubert, E.E.3
Valentim, C.L.4
Rich, J.N.5
-
3
-
-
70349638289
-
Tumour-initiating cells: challenges and opportunities for anticancer drug discovery
-
Zhou BB, Zhang H, Damelin M, Geles KG, Grindley JC, Dirks PB. Tumour-initiating cells: challenges and opportunities for anticancer drug discovery. Nat Rev Drug Discov. 2009; 8:806-823
-
(2009)
Nat Rev Drug Discov
, vol.8
, pp. 806-823
-
-
Zhou, B.B.1
Zhang, H.2
Damelin, M.3
Geles, K.G.4
Grindley, J.C.5
Dirks, P.B.6
-
4
-
-
84904244348
-
Sox2: masterminding the root of cancer
-
Tam WL, Ng HH. Sox2: masterminding the root of cancer. Cancer Cell. 2014; 26:3-5
-
(2014)
Cancer Cell
, vol.26
, pp. 3-5
-
-
Tam, W.L.1
Ng, H.H.2
-
5
-
-
0141842674
-
Identification of a cancer stem cell in human brain tumors
-
Singh SK, Clarke ID, Terasaki M, Bonn VE, Hawkins C, Squire J, Dirks PB. Identification of a cancer stem cell in human brain tumors. Cancer Res. 2003; 63:5821-5828
-
(2003)
Cancer Res
, vol.63
, pp. 5821-5828
-
-
Singh, S.K.1
Clarke, I.D.2
Terasaki, M.3
Bonn, V.E.4
Hawkins, C.5
Squire, J.6
Dirks, P.B.7
-
6
-
-
77957560011
-
A fluorescent rosamine compound selectively stains pluripotent stem cells
-
Im CN, Kang NY, Ha HH, Bi X, Lee JJ, Park SJ, Lee SY, Vendrell M, Kim YK, Lee JS, Li J, Ahn YH, Feng B, et al. A fluorescent rosamine compound selectively stains pluripotent stem cells. Angew Chem Int Ed Engl. 2010; 49:7497-7500
-
(2010)
Angew Chem Int Ed Engl
, vol.49
, pp. 7497-7500
-
-
Im, C.N.1
Kang, N.Y.2
Ha, H.H.3
Bi, X.4
Lee, J.J.5
Park, S.J.6
Lee, S.Y.7
Vendrell, M.8
Kim, Y.K.9
Lee, J.S.10
Li, J.11
Ahn, Y.H.12
Feng, B.13
-
7
-
-
84928194762
-
Glioblastoma stemlike cells: at the root of tumor recurrence and a therapeutic target
-
Jackson M, Hassiotou F, Nowak A. Glioblastoma stemlike cells: at the root of tumor recurrence and a therapeutic target. Carcinogenesis. 2015; 36:177-185
-
(2015)
Carcinogenesis
, vol.36
, pp. 177-185
-
-
Jackson, M.1
Hassiotou, F.2
Nowak, A.3
-
8
-
-
84940107521
-
Targeting Aggressive Cancer Stem Cells in Glioblastoma
-
Seymour T, Nowak A, Kakulas F. Targeting Aggressive Cancer Stem Cells in Glioblastoma. Front Oncol. 2015; 5:159
-
(2015)
Front Oncol
, vol.5
, pp. 159
-
-
Seymour, T.1
Nowak, A.2
Kakulas, F.3
-
9
-
-
84920573170
-
The role of STAT3 signaling in mediating tumor resistance to cancer therapy
-
Tan FH, Putoczki TL, Stylli SS, Luwor RB. The role of STAT3 signaling in mediating tumor resistance to cancer therapy. Curr Drug Targets. 2014; 15:1341-1353
-
(2014)
Curr Drug Targets
, vol.15
, pp. 1341-1353
-
-
Tan, F.H.1
Putoczki, T.L.2
Stylli, S.S.3
Luwor, R.B.4
-
10
-
-
34247600538
-
STAT3 as a central mediator of neoplastic cellular transformation
-
Frank DA. STAT3 as a central mediator of neoplastic cellular transformation. Cancer Lett. 2007; 251:199-210
-
(2007)
Cancer Lett
, vol.251
, pp. 199-210
-
-
Frank, D.A.1
-
11
-
-
84921903048
-
Notch1 induces epithelial-mesenchymal transition and the cancer stem cell phenotype in breast cancer cells and STAT3 plays a key role
-
Zhang X, Zhao X, Shao S, Zuo X, Ning Q, Luo M, Gu S, Zhao X. Notch1 induces epithelial-mesenchymal transition and the cancer stem cell phenotype in breast cancer cells and STAT3 plays a key role. Int J Oncol. 2015; 46:1141-1148
-
(2015)
Int J Oncol
, vol.46
, pp. 1141-1148
-
-
Zhang, X.1
Zhao, X.2
Shao, S.3
Zuo, X.4
Ning, Q.5
Luo, M.6
Gu, S.7
Zhao, X.8
-
12
-
-
84870873242
-
STAT3 mediates resistance of CD44(+)CD24(-/low) breast cancer stem cells to tamoxifen in vitro
-
Wang X, Wang G, Zhao Y, Liu X, Ding Q, Shi J, Ding Y, Wang S. STAT3 mediates resistance of CD44(+)CD24(-/low) breast cancer stem cells to tamoxifen in vitro. J Biomed Res. 2012; 26:325-335
-
(2012)
J Biomed Res
, vol.26
, pp. 325-335
-
-
Wang, X.1
Wang, G.2
Zhao, Y.3
Liu, X.4
Ding, Q.5
Shi, J.6
Ding, Y.7
Wang, S.8
-
13
-
-
84895756231
-
RhoC regulates cancer stem cells in head and neck squamous cell carcinoma by overexpressing IL-6 and phosphorylation of STAT3
-
Islam M, Sharma S, Teknos TN. RhoC regulates cancer stem cells in head and neck squamous cell carcinoma by overexpressing IL-6 and phosphorylation of STAT3. PLoS One. 2014; 9:e88527
-
(2014)
PLoS One
, vol.9
-
-
Islam, M.1
Sharma, S.2
Teknos, T.N.3
-
14
-
-
84949498983
-
p-21 activated kinase 4 (PAK4) maintains stem cell-like phenotypes in pancreatic cancer cells through activation of STAT3 signaling
-
Tyagi N, Marimuthu S, Bhardwaj A, Deshmukh SK, Srivastava SK, Singh AP, McClellan S, Carter JE, Singh S. p-21 activated kinase 4 (PAK4) maintains stem cell-like phenotypes in pancreatic cancer cells through activation of STAT3 signaling. Cancer Lett. 2016; 370:260-267
-
(2016)
Cancer Lett
, vol.370
, pp. 260-267
-
-
Tyagi, N.1
Marimuthu, S.2
Bhardwaj, A.3
Deshmukh, S.K.4
Srivastava, S.K.5
Singh, A.P.6
McClellan, S.7
Carter, J.E.8
Singh, S.9
-
15
-
-
84872192934
-
Upregulation of CXCR4 is functionally crucial for maintenance of stemness in drugresistant non-small cell lung cancer cells
-
Jung MJ, Rho JK, Kim YM, Jung JE, Jin YB, Ko YG, Lee JS, Lee SJ, Lee JC, Park MJ. Upregulation of CXCR4 is functionally crucial for maintenance of stemness in drugresistant non-small cell lung cancer cells. Oncogene. 2013; 32:209-221
-
(2013)
Oncogene
, vol.32
, pp. 209-221
-
-
Jung, M.J.1
Rho, J.K.2
Kim, Y.M.3
Jung, J.E.4
Jin, Y.B.5
Ko, Y.G.6
Lee, J.S.7
Lee, S.J.8
Lee, J.C.9
Park, M.J.10
-
16
-
-
0033523874
-
Bis, a Bcl-2-binding protein that synergizes with Bcl-2 in preventing cell death
-
Lee JH, Takahashi T, Yasuhara N, Inazawa J, Kamada S, Tsujimoto Y. Bis, a Bcl-2-binding protein that synergizes with Bcl-2 in preventing cell death. Oncogene. 1999; 18:6183-6190
-
(1999)
Oncogene
, vol.18
, pp. 6183-6190
-
-
Lee, J.H.1
Takahashi, T.2
Yasuhara, N.3
Inazawa, J.4
Kamada, S.5
Tsujimoto, Y.6
-
17
-
-
79960008971
-
BAG3: a multifaceted protein that regulates major cell pathways
-
Rosati A, Graziano V, De Laurenzi V, Pascale M, Turco MC. BAG3: a multifaceted protein that regulates major cell pathways. Cell Death Dis. 2011; 2:e141
-
(2011)
Cell Death Dis
, vol.2
-
-
Rosati, A.1
Graziano, V.2
De Laurenzi, V.3
Pascale, M.4
Turco, M.C.5
-
18
-
-
84863283179
-
BAG3: a new therapeutic target of human cancers?
-
Zhu H, Liu P, Li J. BAG3: a new therapeutic target of human cancers? Histol Histopathol. 2012; 27:257-261
-
(2012)
Histol Histopathol
, vol.27
, pp. 257-261
-
-
Zhu, H.1
Liu, P.2
Li, J.3
-
19
-
-
84868122918
-
Expression of the antiapoptotic protein BAG3 is a feature of pancreatic adenocarcinoma and its overexpression is associated with poorer survival
-
Rosati A, Bersani S, Tavano F, Dalla Pozza E, De Marco M, Palmieri M, De Laurenzi V, Franco R, Scognamiglio G, Palaia R, Fontana A, di Sebastiano P, Donadelli M, et al. Expression of the antiapoptotic protein BAG3 is a feature of pancreatic adenocarcinoma and its overexpression is associated with poorer survival. Am J Pathol. 2012; 181:1524-1529
-
(2012)
Am J Pathol
, vol.181
, pp. 1524-1529
-
-
Rosati, A.1
Bersani, S.2
Tavano, F.3
Dalla Pozza, E.4
De Marco, M.5
Palmieri, M.6
De Laurenzi, V.7
Franco, R.8
Scognamiglio, G.9
Palaia, R.10
Fontana, A.11
di Sebastiano, P.12
Donadelli, M.13
-
20
-
-
33947542628
-
The antiapoptotic protein BAG3 is expressed in thyroid carcinomas and modulates apoptosis mediated by tumor necrosis factorrelated apoptosis-inducing ligand
-
Chiappetta G, Ammirante M, Basile A, Rosati A, Festa M, Monaco M, Vuttariello E, Pasquinelli R, Arra C, Zerilli M, Todaro M, Stassi G, Pezzullo L, et al. The antiapoptotic protein BAG3 is expressed in thyroid carcinomas and modulates apoptosis mediated by tumor necrosis factorrelated apoptosis-inducing ligand. J Clin Endocrinol Metab. 2007; 92:1159-1163
-
(2007)
J Clin Endocrinol Metab
, vol.92
, pp. 1159-1163
-
-
Chiappetta, G.1
Ammirante, M.2
Basile, A.3
Rosati, A.4
Festa, M.5
Monaco, M.6
Vuttariello, E.7
Pasquinelli, R.8
Arra, C.9
Zerilli, M.10
Todaro, M.11
Stassi, G.12
Pezzullo, L.13
-
21
-
-
79959376413
-
BAG3 protein is overexpressed in human glioblastoma and is a potential target for therapy
-
Festa M, Del Valle L, Khalili K, Franco R, Scognamiglio G, Graziano V, De Laurenzi V, Turco MC, Rosati A. BAG3 protein is overexpressed in human glioblastoma and is a potential target for therapy. Am J Pathol. 2011; 178:2504-2512
-
(2011)
Am J Pathol
, vol.178
, pp. 2504-2512
-
-
Festa, M.1
Del Valle, L.2
Khalili, K.3
Franco, R.4
Scognamiglio, G.5
Graziano, V.6
De Laurenzi, V.7
Turco, M.C.8
Rosati, A.9
-
22
-
-
77955664680
-
Down-modulation of Bis sensitizes cell death in C6 glioma cells induced by oxygen-glucose deprivation
-
Jung SE, Kim YK, Youn DY, Lim MH, Ko JH, Ahn YS, Lee JH. Down-modulation of Bis sensitizes cell death in C6 glioma cells induced by oxygen-glucose deprivation. Brain Res. 2010; 1349:1-10
-
(2010)
Brain Res
, vol.1349
, pp. 1-10
-
-
Jung, S.E.1
Kim, Y.K.2
Youn, D.Y.3
Lim, M.H.4
Ko, J.H.5
Ahn, Y.S.6
Lee, J.H.7
-
23
-
-
58149494120
-
BAG3 gene silencing sensitizes leukemic cells to Bortezomib-induced apoptosis
-
Liu P, Xu B, Li J, Lu H. BAG3 gene silencing sensitizes leukemic cells to Bortezomib-induced apoptosis. FEBS Lett. 2009; 583:401-406
-
(2009)
FEBS Lett
, vol.583
, pp. 401-406
-
-
Liu, P.1
Xu, B.2
Li, J.3
Lu, H.4
-
24
-
-
66149118221
-
HSF1-mediated BAG3 expression attenuates apoptosis in 4-hydroxynonenal-treated colon cancer cells via stabilization of anti-apoptotic Bcl-2 proteins
-
Jacobs AT, Marnett LJ. HSF1-mediated BAG3 expression attenuates apoptosis in 4-hydroxynonenal-treated colon cancer cells via stabilization of anti-apoptotic Bcl-2 proteins. J Biol Chem. 2009; 284:9176-9183
-
(2009)
J Biol Chem
, vol.284
, pp. 9176-9183
-
-
Jacobs, A.T.1
Marnett, L.J.2
-
25
-
-
35949000838
-
BAG3 regulates motility and adhesion of epithelial cancer cells
-
Iwasaki M, Homma S, Hishiya A, Dolezal SJ, Reed JC, Takayama S. BAG3 regulates motility and adhesion of epithelial cancer cells. Cancer Res. 2007; 67:10252-10259
-
(2007)
Cancer Res
, vol.67
, pp. 10252-10259
-
-
Iwasaki, M.1
Homma, S.2
Hishiya, A.3
Dolezal, S.J.4
Reed, J.C.5
Takayama, S.6
-
26
-
-
84896817592
-
BAG3 regulates epithelialmesenchymal transition and angiogenesis in human hepatocellular carcinoma
-
Xiao H, Cheng S, Tong R, Lv Z, Ding C, Du C, Xie H, Zhou L, Wu J, Zheng S. BAG3 regulates epithelialmesenchymal transition and angiogenesis in human hepatocellular carcinoma. Lab Invest. 2014; 94:252-261
-
(2014)
Lab Invest
, vol.94
, pp. 252-261
-
-
Xiao, H.1
Cheng, S.2
Tong, R.3
Lv, Z.4
Ding, C.5
Du, C.6
Xie, H.7
Zhou, L.8
Wu, J.9
Zheng, S.10
-
27
-
-
79951857812
-
BAG3 (BCL2-associated athanogene 3) interacts with MMP-2 to positively regulate invasion by ovarian carcinoma cells
-
Suzuki M, Iwasaki M, Sugio A, Hishiya A, Tanaka R, Endo T, Takayama S, Saito T. BAG3 (BCL2-associated athanogene 3) interacts with MMP-2 to positively regulate invasion by ovarian carcinoma cells. Cancer Lett. 2011; 303:65-71
-
(2011)
Cancer Lett
, vol.303
, pp. 65-71
-
-
Suzuki, M.1
Iwasaki, M.2
Sugio, A.3
Hishiya, A.4
Tanaka, R.5
Endo, T.6
Takayama, S.7
Saito, T.8
-
28
-
-
84884588730
-
PKCdelta-mediated phosphorylation of BAG3 at Ser187 site induces epithelial-mesenchymal transition and enhances invasiveness in thyroid cancer FRO cells
-
Li N, Du ZX, Zong ZH, Liu BQ, Li C, Zhang Q, Wang HQ. PKCdelta-mediated phosphorylation of BAG3 at Ser187 site induces epithelial-mesenchymal transition and enhances invasiveness in thyroid cancer FRO cells. Oncogene. 2013; 32:4539-4548
-
(2013)
Oncogene
, vol.32
, pp. 4539-4548
-
-
Li, N.1
Du, Z.X.2
Zong, Z.H.3
Liu, B.Q.4
Li, C.5
Zhang, Q.6
Wang, H.Q.7
-
29
-
-
84896759879
-
Knockdown of BAG3 induces epithelial-mesenchymal transition in thyroid cancer cells through ZEB1 activation
-
Meng X, Kong DH, Li N, Zong ZH, Liu BQ, Du ZX, Guan Y, Cao L, Wang HQ. Knockdown of BAG3 induces epithelial-mesenchymal transition in thyroid cancer cells through ZEB1 activation. Cell Death Dis. 2014; 5:e1092
-
(2014)
Cell Death Dis
, vol.5
-
-
Meng, X.1
Kong, D.H.2
Li, N.3
Zong, Z.H.4
Liu, B.Q.5
Du, Z.X.6
Guan, Y.7
Cao, L.8
Wang, H.Q.9
-
30
-
-
51449085561
-
Generation of breast cancer stem cells through epithelial-mesenchymal transition
-
Morel AP, Lievre M, Thomas C, Hinkal G, Ansieau S, Puisieux A. Generation of breast cancer stem cells through epithelial-mesenchymal transition. PLoS One. 2008; 3:e2888
-
(2008)
PLoS One
, vol.3
-
-
Morel, A.P.1
Lievre, M.2
Thomas, C.3
Hinkal, G.4
Ansieau, S.5
Puisieux, A.6
-
31
-
-
84907977435
-
Transforming growth factor-beta1-induced epithelial-mesenchymal transition generates ALDH-positive cells with stem cell properties in cholangiocarcinoma
-
Shuang ZY, Wu WC, Xu J, Lin G, Liu YC, Lao XM, Zheng L, Li S. Transforming growth factor-beta1-induced epithelial-mesenchymal transition generates ALDH-positive cells with stem cell properties in cholangiocarcinoma. Cancer Lett. 2014; 354:320-328
-
(2014)
Cancer Lett
, vol.354
, pp. 320-328
-
-
Shuang, Z.Y.1
Wu, W.C.2
Xu, J.3
Lin, G.4
Liu, Y.C.5
Lao, X.M.6
Zheng, L.7
Li, S.8
-
32
-
-
84883069928
-
SNAIL induces epithelial-to-mesenchymal transition and cancer stem cell-like properties in aldehyde dehydroghenasenegative thyroid cancer cells
-
Yasui K, Shimamura M, Mitsutake N, Nagayama Y. SNAIL induces epithelial-to-mesenchymal transition and cancer stem cell-like properties in aldehyde dehydroghenasenegative thyroid cancer cells. Thyroid. 2013; 23:989-996
-
(2013)
Thyroid
, vol.23
, pp. 989-996
-
-
Yasui, K.1
Shimamura, M.2
Mitsutake, N.3
Nagayama, Y.4
-
33
-
-
84931378854
-
Enhancement of SOX-2 expression and ROS accumulation by culture of A172 glioblastoma cells under non-adherent culture conditions
-
Im CN, Yun HH, Yoo HJ, Park MJ, Lee JH. Enhancement of SOX-2 expression and ROS accumulation by culture of A172 glioblastoma cells under non-adherent culture conditions. Oncol Rep. 2015; 34:920-928
-
(2015)
Oncol Rep
, vol.34
, pp. 920-928
-
-
Im, C.N.1
Yun, H.H.2
Yoo, H.J.3
Park, M.J.4
Lee, J.H.5
-
34
-
-
57449095814
-
PPARgamma agonists inhibit growth and expansion of CD133+ brain tumour stem cells
-
Chearwae W, Bright JJ. PPARgamma agonists inhibit growth and expansion of CD133+ brain tumour stem cells. Br J Cancer. 2008; 99:2044-2053
-
(2008)
Br J Cancer
, vol.99
, pp. 2044-2053
-
-
Chearwae, W.1
Bright, J.J.2
-
35
-
-
84899032575
-
STAT3 phosphorylation at tyrosine 705 and serine 727 differentially regulates mouse ESC fates
-
Huang G, Yan H, Ye S, Tong C, Ying QL. STAT3 phosphorylation at tyrosine 705 and serine 727 differentially regulates mouse ESC fates. Stem Cells. 2014; 32:1149-1160
-
(2014)
Stem Cells
, vol.32
, pp. 1149-1160
-
-
Huang, G.1
Yan, H.2
Ye, S.3
Tong, C.4
Ying, Q.L.5
-
36
-
-
84927934042
-
BIS targeting induces cellular senescence through the regulation of 14-3-3 zeta/STAT3/SKP2/p27 in glioblastoma cells
-
Lee JJ, Lee JS, Cui MN, Yun HH, Kim HY, Lee SH, Lee JH. BIS targeting induces cellular senescence through the regulation of 14-3-3 zeta/STAT3/SKP2/p27 in glioblastoma cells. Cell Death Dis. 2014; 5:e1537
-
(2014)
Cell Death Dis
, vol.5
-
-
Lee, J.J.1
Lee, J.S.2
Cui, M.N.3
Yun, H.H.4
Kim, H.Y.5
Lee, S.H.6
Lee, J.H.7
-
37
-
-
43049165453
-
The epithelialmesenchymal transition generates cells with properties of stem cells
-
Mani SA, Guo W, Liao MJ, Eaton EN, Ayyanan A, Zhou AY, Brooks M, Reinhard F, Zhang CC, Shipitsin M, Campbell LL, Polyak K, Brisken C, et al. The epithelialmesenchymal transition generates cells with properties of stem cells. Cell. 2008; 133:704-715
-
(2008)
Cell
, vol.133
, pp. 704-715
-
-
Mani, S.A.1
Guo, W.2
Liao, M.J.3
Eaton, E.N.4
Ayyanan, A.5
Zhou, A.Y.6
Brooks, M.7
Reinhard, F.8
Zhang, C.C.9
Shipitsin, M.10
Campbell, L.L.11
Polyak, K.12
Brisken, C.13
-
38
-
-
84922395039
-
Epithelial to mesenchymal transition inducing transcription factors and metastatic cancer
-
Tania M, Khan MA, Fu J. Epithelial to mesenchymal transition inducing transcription factors and metastatic cancer. Tumour Biol. 2014; 35:7335-7342
-
(2014)
Tumour Biol
, vol.35
, pp. 7335-7342
-
-
Tania, M.1
Khan, M.A.2
Fu, J.3
-
39
-
-
84949294600
-
Multiple regulation pathways and pivotal biological functions of STAT3 in cancer
-
Yuan J, Zhang F, Niu R. Multiple regulation pathways and pivotal biological functions of STAT3 in cancer. Sci Rep. 2015; 5:17663
-
(2015)
Sci Rep
, vol.5
, pp. 17663
-
-
Yuan, J.1
Zhang, F.2
Niu, R.3
-
40
-
-
84901981332
-
Down-modulation of Bis reduces the invasive ability of glioma cells induced by TPA, through NF-kappaB mediated activation of MMP-9
-
Lee YD, Cui MN, Yoon HH, Kim HY, Oh IH, Lee JH. Down-modulation of Bis reduces the invasive ability of glioma cells induced by TPA, through NF-kappaB mediated activation of MMP-9. BMB Rep. 2014; 47:262-267
-
(2014)
BMB Rep
, vol.47
, pp. 262-267
-
-
Lee, Y.D.1
Cui, M.N.2
Yoon, H.H.3
Kim, H.Y.4
Oh, I.H.5
Lee, J.H.6
-
41
-
-
84893556391
-
Inhibition of STAT3 reduces astrocytoma cell invasion and constitutive activation of STAT3 predicts poor prognosis in human astrocytoma
-
Liang Q, Ma C, Zhao Y, Gao G, Ma J. Inhibition of STAT3 reduces astrocytoma cell invasion and constitutive activation of STAT3 predicts poor prognosis in human astrocytoma. PLoS One. 2013; 8:e84723
-
(2013)
PLoS One
, vol.8
-
-
Liang, Q.1
Ma, C.2
Zhao, Y.3
Gao, G.4
Ma, J.5
-
42
-
-
84880059674
-
Cancer stem-like cell marker CD44 promotes bone metastases by enhancing tumorigenicity, cell motility, and hyaluronan production
-
Hiraga T, Ito S, Nakamura H. Cancer stem-like cell marker CD44 promotes bone metastases by enhancing tumorigenicity, cell motility, and hyaluronan production. Cancer Res. 2013; 73:4112-4122
-
(2013)
Cancer Res
, vol.73
, pp. 4112-4122
-
-
Hiraga, T.1
Ito, S.2
Nakamura, H.3
-
43
-
-
38349075007
-
CD133 negative glioma cells form tumors in nude rats and give rise to CD133 positive cells
-
Wang J, Sakariassen PO, Tsinkalovsky O, Immervoll H, Boe SO, Svendsen A, Prestegarden L, Rosland G, Thorsen F, Stuhr L, Molven A, Bjerkvig R, Enger PO. CD133 negative glioma cells form tumors in nude rats and give rise to CD133 positive cells. Int J Cancer. 2008; 122:761-768
-
(2008)
Int J Cancer
, vol.122
, pp. 761-768
-
-
Wang, J.1
Sakariassen, P.O.2
Tsinkalovsky, O.3
Immervoll, H.4
Boe, S.O.5
Svendsen, A.6
Prestegarden, L.7
Rosland, G.8
Thorsen, F.9
Stuhr, L.10
Molven, A.11
Bjerkvig, R.12
Enger, P.O.13
-
44
-
-
66149152637
-
Limits of CD133 as a marker of glioma self-renewing cells
-
Clement V, Dutoit V, Marino D, Dietrich PY, Radovanovic I. Limits of CD133 as a marker of glioma self-renewing cells. Int J Cancer. 2009; 125:244-248
-
(2009)
Int J Cancer
, vol.125
, pp. 244-248
-
-
Clement, V.1
Dutoit, V.2
Marino, D.3
Dietrich, P.Y.4
Radovanovic, I.5
-
45
-
-
84930671246
-
Pigment Epithelium-Derived Factor (PEDF) Expression Induced by EGFRvIII Promotes Self-renewal and Tumor Progression of Glioma Stem Cells
-
Yin J, Park G, Kim TH, Hong JH, Kim YJ, Jin X, Kang S, Jung JE, Kim JY, Yun H, Lee JE, Kim M, Chung J, et al. Pigment Epithelium-Derived Factor (PEDF) Expression Induced by EGFRvIII Promotes Self-renewal and Tumor Progression of Glioma Stem Cells. PLoS Biol. 2015; 13:e1002152
-
(2015)
PLoS Biol
, vol.13
-
-
Yin, J.1
Park, G.2
Kim, T.H.3
Hong, J.H.4
Kim, Y.J.5
Jin, X.6
Kang, S.7
Jung, J.E.8
Kim, J.Y.9
Yun, H.10
Lee, J.E.11
Kim, M.12
Chung, J.13
-
46
-
-
84873695296
-
PI3K/Akt and Stat3 signaling regulated by PTEN control of the cancer stem cell population, proliferation and senescence in a glioblastoma cell line
-
Moon SH, Kim DK, Cha Y, Jeon I, Song J, Park KS. PI3K/Akt and Stat3 signaling regulated by PTEN control of the cancer stem cell population, proliferation and senescence in a glioblastoma cell line. Int J Oncol. 2013; 42:921-928
-
(2013)
Int J Oncol
, vol.42
, pp. 921-928
-
-
Moon, S.H.1
Kim, D.K.2
Cha, Y.3
Jeon, I.4
Song, J.5
Park, K.S.6
-
47
-
-
84879000598
-
Phosphorylation of EZH2 activates STAT3 signaling via STAT3 methylation and promotes tumorigenicity of glioblastoma stem-like cells
-
Kim E, Kim M, Woo DH, Shin Y, Shin J, Chang N, Oh YT, Kim H, Rheey J, Nakano I, Lee C, Joo KM, Rich JN, et al. Phosphorylation of EZH2 activates STAT3 signaling via STAT3 methylation and promotes tumorigenicity of glioblastoma stem-like cells. Cancer Cell. 2013; 23:839-852
-
(2013)
Cancer Cell
, vol.23
, pp. 839-852
-
-
Kim, E.1
Kim, M.2
Woo, D.H.3
Shin, Y.4
Shin, J.5
Chang, N.6
Oh, Y.T.7
Kim, H.8
Rheey, J.9
Nakano, I.10
Lee, C.11
Joo, K.M.12
Rich, J.N.13
-
48
-
-
84923376487
-
Inositol Polyphosphate-5-Phosphatase F (INPP5F) inhibits STAT3 activity and suppresses gliomas tumorigenicity
-
Kim HS, Li A, Ahn S, Song H, Zhang W. Inositol Polyphosphate-5-Phosphatase F (INPP5F) inhibits STAT3 activity and suppresses gliomas tumorigenicity. Sci Rep. 2014; 4:7330
-
(2014)
Sci Rep
, vol.4
, pp. 7330
-
-
Kim, H.S.1
Li, A.2
Ahn, S.3
Song, H.4
Zhang, W.5
-
49
-
-
84883682803
-
Constitutive activation of signal transducer and activator of transcription 3 (STAT3) and nuclear factor kappaB signaling in glioblastoma cancer stem cells regulates the Notch pathway
-
Garner JM, Fan M, Yang CH, Du Z, Sims M, Davidoff AM, Pfeffer LM. Constitutive activation of signal transducer and activator of transcription 3 (STAT3) and nuclear factor kappaB signaling in glioblastoma cancer stem cells regulates the Notch pathway. J Biol Chem. 2013; 288:26167-26176
-
(2013)
J Biol Chem
, vol.288
, pp. 26167-26176
-
-
Garner, J.M.1
Fan, M.2
Yang, C.H.3
Du, Z.4
Sims, M.5
Davidoff, A.M.6
Pfeffer, L.M.7
-
50
-
-
84943542776
-
Peptide-like Polymers Exerting Effective Glioma-Targeted siRNA Delivery and Release for Therapeutic Application
-
An S, He D, Wagner E, Jiang C. Peptide-like Polymers Exerting Effective Glioma-Targeted siRNA Delivery and Release for Therapeutic Application. Small. 2015; 11:5142-5150
-
(2015)
Small
, vol.11
, pp. 5142-5150
-
-
An, S.1
He, D.2
Wagner, E.3
Jiang, C.4
-
51
-
-
84949999070
-
Gold-nanorods-siRNA nanoplex for improved photothermal therapy by gene silencing
-
Wang BK, Yu XF, Wang JH, Li ZB, Li PH, Wang H, Song L, Chu PK, Li C. Gold-nanorods-siRNA nanoplex for improved photothermal therapy by gene silencing. Biomaterials. 2015; 78:27-39
-
(2015)
Biomaterials
, vol.78
, pp. 27-39
-
-
Wang, B.K.1
Yu, X.F.2
Wang, J.H.3
Li, Z.B.4
Li, P.H.5
Wang, H.6
Song, L.7
Chu, P.K.8
Li, C.9
-
53
-
-
79960652801
-
Molecular chaperones in protein folding and proteostasis
-
Hartl FU, Bracher A, Hayer-Hartl M. Molecular chaperones in protein folding and proteostasis. Nature. 2011; 475:324-332
-
(2011)
Nature
, vol.475
, pp. 324-332
-
-
Hartl, F.U.1
Bracher, A.2
Hayer-Hartl, M.3
-
54
-
-
79551609332
-
BAG3 mediates chaperone-based aggresome-targeting and selective autophagy of misfolded proteins
-
Gamerdinger M, Kaya AM, Wolfrum U, Clement AM, Behl C. BAG3 mediates chaperone-based aggresome-targeting and selective autophagy of misfolded proteins. EMBO Rep. 2011; 12:149-156
-
(2011)
EMBO Rep
, vol.12
, pp. 149-156
-
-
Gamerdinger, M.1
Kaya, A.M.2
Wolfrum, U.3
Clement, A.M.4
Behl, C.5
-
55
-
-
38949184241
-
HspB8 and Bag3: a new chaperone complex targeting misfolded proteins to macroautophagy
-
Carra S, Seguin SJ, Landry J. HspB8 and Bag3: a new chaperone complex targeting misfolded proteins to macroautophagy. Autophagy. 2008; 4:237-239
-
(2008)
Autophagy
, vol.4
, pp. 237-239
-
-
Carra, S.1
Seguin, S.J.2
Landry, J.3
-
56
-
-
0039172708
-
The ubiquitin-related BAG-1 provides a link between the molecular chaperones Hsc70/Hsp70 and the proteasome
-
Luders J, Demand J, Hohfeld J. The ubiquitin-related BAG-1 provides a link between the molecular chaperones Hsc70/Hsp70 and the proteasome. Journal of Biological Chemistry. 2000; 275:4613-4617
-
(2000)
Journal of Biological Chemistry
, vol.275
, pp. 4613-4617
-
-
Luders, J.1
Demand, J.2
Hohfeld, J.3
-
57
-
-
84907166419
-
BAG3 induces the sequestration of proteasomal clients into cytoplasmic puncta: implications for a proteasome-toautophagy switch
-
Minoia M, Boncoraglio A, Vinet J, Morelli FF, Brunsting JF, Poletti A, Krom S, Reits E, Kampinga HH, Carra S. BAG3 induces the sequestration of proteasomal clients into cytoplasmic puncta: implications for a proteasome-toautophagy switch. Autophagy. 2014; 10:1603-1621
-
(2014)
Autophagy
, vol.10
, pp. 1603-1621
-
-
Minoia, M.1
Boncoraglio, A.2
Vinet, J.3
Morelli, F.F.4
Brunsting, J.F.5
Poletti, A.6
Krom, S.7
Reits, E.8
Kampinga, H.H.9
Carra, S.10
-
58
-
-
65449117176
-
Protein quality control during aging involves recruitment of the macroautophagy pathway by BAG3
-
Gamerdinger M, Hajieva P, Kaya AM, Wolfrum U, Hartl FU, Behl C. Protein quality control during aging involves recruitment of the macroautophagy pathway by BAG3. Embo Journal. 2009; 28:889-901
-
(2009)
Embo Journal
, vol.28
, pp. 889-901
-
-
Gamerdinger, M.1
Hajieva, P.2
Kaya, A.M.3
Wolfrum, U.4
Hartl, F.U.5
Behl, C.6
-
59
-
-
0033534588
-
An evolutionarily conserved family of Hsp70/Hsc70 molecular chaperone regulators
-
Takayama S, Xie Z, Reed JC. An evolutionarily conserved family of Hsp70/Hsc70 molecular chaperone regulators. J Biol Chem. 1999; 274:781-786
-
(1999)
J Biol Chem
, vol.274
, pp. 781-786
-
-
Takayama, S.1
Xie, Z.2
Reed, J.C.3
-
60
-
-
66149118221
-
HSF1-mediated BAG3 Expression Attenuates Apoptosis in 4-Hydroxynonenal-treated Colon Cancer Cells via Stabilization of Anti-apoptotic Bcl-2 Proteins
-
Jacobs AT, Marnett LJ. HSF1-mediated BAG3 Expression Attenuates Apoptosis in 4-Hydroxynonenal-treated Colon Cancer Cells via Stabilization of Anti-apoptotic Bcl-2 Proteins. Journal of Biological Chemistry. 2009; 284:9176-9183
-
(2009)
Journal of Biological Chemistry
, vol.284
, pp. 9176-9183
-
-
Jacobs, A.T.1
Marnett, L.J.2
-
61
-
-
84855514725
-
BAG3 Down-Modulation Reduces Anaplastic Thyroid Tumor Growth by Enhancing Proteasome-Mediated Degradation of BRAF Protein
-
Chiappetta G, Basile A, Arra C, Califano D, Pasquinelli R, Barbieri A, De Simone V, Rea D, Giudice A, Pezzullo L, De Laurenzi V, Botti G, Losito S, et al. BAG3 Down-Modulation Reduces Anaplastic Thyroid Tumor Growth by Enhancing Proteasome-Mediated Degradation of BRAF Protein. Journal of Clinical Endocrinology & Metabolism. 2012; 97:E115-E120
-
(2012)
Journal of Clinical Endocrinology & Metabolism
, vol.97
, pp. E115-E120
-
-
Chiappetta, G.1
Basile, A.2
Arra, C.3
Califano, D.4
Pasquinelli, R.5
Barbieri, A.6
De Simone, V.7
Rea, D.8
Giudice, A.9
Pezzullo, L.10
De Laurenzi, V.11
Botti, G.12
Losito, S.13
-
62
-
-
84874817068
-
The Stress Protein BAG3 Stabilizes Mcl-1 Protein and Promotes Survival of Cancer Cells and Resistance to Antagonist ABT-737
-
Boiani M, Daniel C, Liu XY, Hogarty MD, Marnett LJ. The Stress Protein BAG3 Stabilizes Mcl-1 Protein and Promotes Survival of Cancer Cells and Resistance to Antagonist ABT-737. Journal of Biological Chemistry. 2013; 288:6980-6990
-
(2013)
Journal of Biological Chemistry
, vol.288
, pp. 6980-6990
-
-
Boiani, M.1
Daniel, C.2
Liu, X.Y.3
Hogarty, M.D.4
Marnett, L.J.5
-
63
-
-
77952112425
-
IKK gamma protein is a target of BAG3 regulatory activity in human tumor growth
-
Ammirante M, Rosati A, Arra C, Basile A, Falco A, Festa M, Pascale M, d'Avenia M, Marzullo L, Belisario MA, De Marco M, Barbieri A, Giudice A, et al. IKK gamma protein is a target of BAG3 regulatory activity in human tumor growth. Proceedings of the National Academy of Sciences of the United States of America. 2010; 107:7497-7502
-
(2010)
Proceedings of the National Academy of Sciences of the United States of America
, vol.107
, pp. 7497-7502
-
-
Ammirante, M.1
Rosati, A.2
Arra, C.3
Basile, A.4
Falco, A.5
Festa, M.6
Pascale, M.7
d'Avenia, M.8
Marzullo, L.9
Belisario, M.A.10
De Marco, M.11
Barbieri, A.12
Giudice, A.13
-
64
-
-
84885154570
-
Bcl2-associated Athanogene 3 Interactome Analysis Reveals a New Role in Modulating Proteasome Activity
-
Chen Y, Yang LN, Cheng L, Tu S, Guo SJ, Le HY, Xiong Q, Mo R, Li CY, Jeong JS, Jiang LZ, Blackshaw S, Bi LJ, et al. Bcl2-associated Athanogene 3 Interactome Analysis Reveals a New Role in Modulating Proteasome Activity. Molecular & Cellular Proteomics. 2013; 12:2804-2819
-
(2013)
Molecular & Cellular Proteomics
, vol.12
, pp. 2804-2819
-
-
Chen, Y.1
Yang, L.N.2
Cheng, L.3
Tu, S.4
Guo, S.J.5
Le, H.Y.6
Xiong, Q.7
Mo, R.8
Li, C.Y.9
Jeong, J.S.10
Jiang, L.Z.11
Blackshaw, S.12
Bi, L.J.13
-
65
-
-
85016641550
-
Myosin heavy chain is stabilized by BCL-2 interacting cell death suppressor (BIS) in skeletal muscle
-
Hong J, Park JS, Lee H, Jeong J, Hyeon Yun H, Yun Kim H, Ko YG, Lee JH. Myosin heavy chain is stabilized by BCL-2 interacting cell death suppressor (BIS) in skeletal muscle. Exp Mol Med. 2016; 48:e225
-
(2016)
Exp Mol Med
, vol.48
-
-
Hong, J.1
Park, J.S.2
Lee, H.3
Jeong, J.4
Hyeon Yun, H.5
Yun Kim, H.6
Ko, Y.G.7
Lee, J.H.8
-
66
-
-
84973617664
-
Characterization of H460R, a Radioresistant Human Lung Cancer Cell Line, and Involvement of Syntrophin Beta 2 (SNTB2) in Radioresistance
-
Im CN, Kim BM, Moon EY, Hong DW, Park JW, Hong SH. Characterization of H460R, a Radioresistant Human Lung Cancer Cell Line, and Involvement of Syntrophin Beta 2 (SNTB2) in Radioresistance. Genomics Inform. 2013; 11:245-253
-
(2013)
Genomics Inform
, vol.11
, pp. 245-253
-
-
Im, C.N.1
Kim, B.M.2
Moon, E.Y.3
Hong, D.W.4
Park, J.W.5
Hong, S.H.6
|