Bis deficiency results in early lethality with metabolic deterioration and involution of spleen and thymus

American Journal of Physiology - Endocrinology and Metabolism

Volumn 295, Issue 6, 2008, Pages

  Youn, Dong Ye ^a   Lee, Dong Hyoung ^a   Lim, Mi Hyun ^a   Yoon, Jung Sook ^a   Ji, Hee Lim ^a   Seung, Eun Jung ^a   Chung, Eun Yeum ^a   Cheol, Whee Park ^a   Youn, Ho Joong ^a   Lee, Jae Seon ^b   Lee, Seong Beom ^a   Ikawa, Masahito ^c   Okabe, Masaru ^c   Tsujimoto, Yoshihide ^d,e   Lee, Jeong Hwa ^a,f  

^a The Catholic University of Korea   (South Korea)

^b Korea Institute of Radiation and Medical Science   (South Korea)

^c OSAKA UNIVERSITY   (Japan)

^d OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

^e JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^f NONE   (South Korea)

Author keywords

bis; Hypoglycemia; Knockout

Indexed keywords

CHOLESTEROL; INHIBITOR OF APOPTOSIS PROTEIN; PROTEIN BIS; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BIS GENE; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DETERIORATION; EXON; FATTY ACID OXIDATION; FATTY LIVER; GENE; GENE DISRUPTION; GENE EXPRESSION PROFILING; GENE TARGETING; GLUCONEOGENESIS; GROWTH RETARDATION; HYPOGLYCEMIA; INVOLUTION; LETHALITY; LEUKOCYTE; LOXP SITE; MALE; METABOLISM; MOUSE; NONHUMAN; NUTRITIONAL DISORDER; POLYMERASE CHAIN REACTION; POSTNATAL GROWTH; PRIORITY JOURNAL; PROTEIN DEFICIENCY; SOUTHERN BLOTTING; SPLEEN; SPLEEN CELL; SPLEEN WEIGHT; SURVIVAL; THYMOCYTE; THYMUS; TRIACYLGLYCEROL BLOOD LEVEL; WESTERN BLOTTING; WILD TYPE;

ANIMALS; CARRIER PROTEINS; CELL COUNT; CELL DEATH; CELLS, CULTURED; EMBRYO LOSS; EMBRYO, MAMMALIAN; FEMALE; GENE TARGETING; GENES, LETHAL; MALE; METABOLIC DISEASES; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; ORGAN SIZE; SPLEEN; THYMUS GLAND;

EID: 57349143456     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.90704.2008     Document Type: Article

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