Fisetin, a dietary flavonoid, induces apoptosis of cancer cells by inhibiting HSF1 activity through blocking its binding to the hsp70 promoter

Carcinogenesis

Volumn 36, Issue 6, 2015, Pages 696-706

  Kim, Joo Ae ^a,b   Lee, Somyoung ^a,b   Kim, Da Eun ^a,b   Kim, Moonil ^a,b   Kwon, Byoung Mog ^a,b   Han, Dong Cho ^a,b  

^a Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^b University of Science and Technology (UST)   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

BCL 2 ASSOCIATED ATHANOGENE DOMAIN 3 PROTEIN; FISETIN; HEAT SHOCK PROTEIN 27; HEAT SHOCK PROTEIN 70; HEAT SHOCK TRANSCRIPTION FACTOR 1; LUCIFERASE; PROTEIN; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; APOPTOSIS REGULATORY PROTEIN; BAG3 PROTEIN, HUMAN; DNA BINDING PROTEIN; FLAVONOID; HEAT SHOCK TRANSCRIPTION FACTOR; HSPB1 PROTEIN, HUMAN; MCL1 PROTEIN, HUMAN; PROTEIN BCL 2; PROTEIN BCL X; PROTEIN BINDING; PROTEIN MCL 1; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TRANSCRIPTION FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CANCER CELL; CANCER INHIBITION; CELL DEATH; CELL PROLIFERATION; CELL SCREENING; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; FEMALE; HEAT SHOCK; HUMAN; HUMAN CELL; IC50; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; ANIMAL; ANTAGONISTS AND INHIBITORS; BAGG ALBINO MOUSE; BINDING SITE; BIOSYNTHESIS; DRUG EFFECTS; GENETICS; HCT116 CELL LINE; METABOLISM; NEOPLASMS; NUDE MOUSE; TUMOR CELL LINE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BCL-X PROTEIN; BINDING SITES; CELL LINE, TUMOR; CELL PROLIFERATION; DNA-BINDING PROTEINS; FEMALE; FLAVONOIDS; HCT116 CELLS; HSP27 HEAT-SHOCK PROTEINS; HSP70 HEAT-SHOCK PROTEINS; HUMANS; MICE; MICE, INBRED BALB C; MICE, NUDE; MYELOID CELL LEUKEMIA SEQUENCE 1 PROTEIN; NEOPLASMS; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; PROTO-ONCOGENE PROTEINS C-BCL-2; TRANSCRIPTION FACTORS;

EID: 84941618262     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgv045     Document Type: Article

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