Validation of the Hsp70-Bag3 protein-protein interaction as a potential therapeutic target in cancer

Molecular Cancer Therapeutics

Volumn 14, Issue 3, 2015, Pages 642-648

  Li, Xiaokai ^a   Colvin, Teresa ^b   Rauch, Jennifer N ^a   Acosta Alvear, Diego ^c   Kampmann, Martin ^c   Dunyak, Bryan ^a   Hann, Byron ^d   Aftab, Blake T ^d   Murnane, Megan ^d   Cho, Min ^c   Walter, Peter ^c   Weissman, Jonathan S ^c   Sherman, Michael Y ^b   Gestwicki, Jason E ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; BAG 1 PROTEIN; BAG 3 PROTEIN; HEAT SHOCK PROTEIN 70; JG 98; PROTEIN P21; PROTEIN P27; UNCLASSIFIED DRUG; APOPTOSIS REGULATORY PROTEIN; BAG3 PROTEIN, HUMAN; CDKN1A PROTEIN, HUMAN; CYCLIN DEPENDENT KINASE INHIBITOR 1A; CYCLINE; FORKHEAD BOX PROTEIN M1; FORKHEAD TRANSCRIPTION FACTOR; FOXM1 PROTEIN, HUMAN; P27 ANTIGEN; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CANCER CELL LINE; CANCER THERAPY; CONTROLLED STUDY; DRUG EFFICACY; HUMAN; HUMAN CELL; MOUSE; NEOPLASM; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; VALIDATION PROCESS; ANIMAL; CELL PROLIFERATION; DRUG EFFECTS; GENE EXPRESSION REGULATION; HELA CELL LINE; HT-29 CELL LINE; MCF-7 CELL LINE; METABOLISM; PHYSIOLOGY; PROTEIN DOMAIN; TUMOR CELL LINE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS REGULATORY PROTEINS; CELL LINE, TUMOR; CELL PROLIFERATION; CYCLIN-DEPENDENT KINASE INHIBITOR P21; FORKHEAD BOX PROTEIN M1; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION, NEOPLASTIC; HELA CELLS; HSP70 HEAT-SHOCK PROTEINS; HT29 CELLS; HUMANS; MCF-7 CELLS; MICE; PROLIFERATING CELL NUCLEAR ANTIGEN; PROTEIN INTERACTION DOMAINS AND MOTIFS;

EID: 84929597660     PISSN: 15357163     EISSN: 15388514     Source Type: Journal    
DOI: 10.1158/1535-7163.MCT-14-0650     Document Type: Article

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