메뉴 건너뛰기




Volumn 6, Issue 2, 2017, Pages 115-133

Progress of: In vivo studies on the systemic toxicities induced by titanium dioxide nanoparticles

Author keywords

[No Author keywords available]

Indexed keywords

TITANIUM DIOXIDE NANOPARTICLE;

EID: 85014839615     PISSN: 2045452X     EISSN: 20454538     Source Type: Journal    
DOI: 10.1039/c6tx00338a     Document Type: Review
Times cited : (77)

References (145)
  • 1
    • 0035647677 scopus 로고    scopus 로고
    • Inter nation strategy or nanotechnology msearehand development
    • M. C. Roco Inter nation strategy or nanotechnology msearehand development J. Toxicol. Sci. 2001 3 353 360
    • (2001) J. Toxicol. Sci. , vol.3 , pp. 353-360
    • Roco, M.C.1
  • 5
    • 2942608902 scopus 로고    scopus 로고
    • Optical characteristics of titanium oxide interference film and the film laminated with oxides and their application for cosmetics
    • T. Kaida K. Kobayashi M. Adachi F. Suzuki Optical characteristics of titanium oxide interference film and the film laminated with oxides and their application for cosmetics J. Cosmet. Sci. 2004 55 2 219 220
    • (2004) J. Cosmet. Sci. , vol.55 , Issue.2 , pp. 219-220
    • Kaida, T.1    Kobayashi, K.2    Adachi, M.3    Suzuki, F.4
  • 6
    • 0141594997 scopus 로고    scopus 로고
    • The potential environmental impact of engineerded nanomaterials
    • V. L. Colvin The potential environmental impact of engineerded nanomaterials Nat. Biotechnol. 2003 21 10 1166 1170
    • (2003) Nat. Biotechnol. , vol.21 , Issue.10 , pp. 1166-1170
    • Colvin, V.L.1
  • 7
    • 77349118986 scopus 로고    scopus 로고
    • Deposition and biokinetics of inhaled nanoparticles
    • M. Geiser W. G. Kreyling Deposition and biokinetics of inhaled nanoparticles Part. Fibre Toxicol. 2010 7 2
    • (2010) Part. Fibre Toxicol. , vol.7 , pp. 2
    • Geiser, M.1    Kreyling, W.G.2
  • 9
    • 84927649790 scopus 로고    scopus 로고
    • Critical review of public health regulations of titanium dioxide, a human food additive
    • B. Jovanović Critical review of public health regulations of titanium dioxide, a human food additive Integr. Environ. Assess. Manage. 2015 11 1 10 20
    • (2015) Integr. Environ. Assess. Manage. , vol.11 , Issue.1 , pp. 10-20
    • Jovanović, B.1
  • 10
    • 84876113687 scopus 로고    scopus 로고
    • Titanium dioxide nanoparticles: A review of current toxicological data
    • H. Shi R. Magaye V. Castranova J. Zhao Titanium dioxide nanoparticles: a review of current toxicological data Part. Fibre Toxicol. 2013 10 15
    • (2013) Part. Fibre Toxicol. , vol.10 , pp. 15
    • Shi, H.1    Magaye, R.2    Castranova, V.3    Zhao, J.4
  • 11
    • 84862277870 scopus 로고    scopus 로고
    • Toxicological effects of titanium dioxide nanoparticles: A review of in vivo studies
    • I. Iavicoli V. Leso A. Berggamschi Toxicological effects of titanium dioxide nanoparticles: A review of in vivo studies J. Nanomater. 2012 2012 36
    • (2012) J. Nanomater. , vol.2012 , pp. 36
    • Iavicoli, I.1    Leso, V.2    Berggamschi, A.3
  • 12
    • 85014827449 scopus 로고    scopus 로고
    • Prospect on Toxicity and safety of nano titanium dioxide
    • X. R. Liu M. Tang Prospect on Toxicity and safety of nano titanium dioxide J. Southeast Univ. 2011 30 6 945 952
    • (2011) J. Southeast Univ. , vol.30 , Issue.6 , pp. 945-952
    • Liu, X.R.1    Tang, M.2
  • 13
    • 78650298993 scopus 로고    scopus 로고
    • Risks from accidental exposures to engineered nanoparticles and neurological health effects: A critical review
    • M. Simko M. O. Mattsson Risks from accidental exposures to engineered nanoparticles and neurological health effects: a critical review Part. Fibre Toxicol. 2010 7 42
    • (2010) Part. Fibre Toxicol. , vol.7 , pp. 42
    • Simko, M.1    Mattsson, M.O.2
  • 14
    • 35448991054 scopus 로고    scopus 로고
    • Reevaluation of pulmonary titanium dioxide nanoparticle distribution using the relative deposition index: Evidence for clearance through microvasculature
    • C. Muhlfeld M. Geiser N. Kapp P. Gehr B. Rothen-Rutishauser Reevaluation of pulmonary titanium dioxide nanoparticle distribution using the "relative deposition index": Evidence for clearance through microvasculature Part. Fibre Toxicol. 2007 4 7
    • (2007) Part. Fibre Toxicol. , vol.4 , pp. 7
    • Muhlfeld, C.1    Geiser, M.2    Kapp, N.3    Gehr, P.4    Rothen-Rutishauser, B.5
  • 16
    • 60649113053 scopus 로고    scopus 로고
    • Pulmonary response to intratracheal instillation of ultrafine versus fine titanium dioxide: Role of particle surface area
    • T. M. Sager C. Kommineni V. Castranova Pulmonary response to intratracheal instillation of ultrafine versus fine titanium dioxide: role of particle surface area Part. Fibre Toxicol. 2008 5 17
    • (2008) Part. Fibre Toxicol. , vol.5 , pp. 17
    • Sager, T.M.1    Kommineni, C.2    Castranova, V.3
  • 17
    • 79952112961 scopus 로고    scopus 로고
    • Systematic influence induced by 3 nm titanium dioxide following intratracheal instillation of mice
    • Y. Li J. Li J. Yin W. Li C. Kang Q. Huang Q. Li Systematic influence induced by 3 nm titanium dioxide following intratracheal instillation of mice J. Nanosci. Nanotechnol. 2010 10 8544 8549
    • (2010) J. Nanosci. Nanotechnol. , vol.10 , pp. 8544-8549
    • Li, Y.1    Li, J.2    Yin, J.3    Li, W.4    Kang, C.5    Huang, Q.6    Li, Q.7
  • 18
    • 85014832560 scopus 로고    scopus 로고
    • 1H NMR based metabonomics in rat splasma
    • 1H NMR based metabonomics in rat splasma Proc. ICNT 2008 12 3 19 23
    • (2008) Proc. ICNT , vol.12 , Issue.3 , pp. 19-23
    • Wang, S.1    Tang, M.2    Zhang, T.3
  • 20
    • 0036183331 scopus 로고    scopus 로고
    • Fine and ultrafine particles of the diet: Influence on the mucosal immune response and association with Crohn's disease
    • M. C. Lomer R. P. Thompson J. J. Powell Fine and ultrafine particles of the diet: influence on the mucosal immune response and association with Crohn's disease Proc. Nutr. Soc. 2002 61 123 130
    • (2002) Proc. Nutr. Soc. , vol.61 , pp. 123-130
    • Lomer, M.C.1    Thompson, R.P.2    Powell, J.J.3
  • 22
    • 0035206137 scopus 로고    scopus 로고
    • Gastrointestinal persorption and tissue distribution of differently sized colloidal gold nanoparticles
    • J. F. Hillyer R. M. Albrecht Gastrointestinal persorption and tissue distribution of differently sized colloidal gold nanoparticles J. Pharm. Sci. 2001 90 1927 1936
    • (2001) J. Pharm. Sci. , vol.90 , pp. 1927-1936
    • Hillyer, J.F.1    Albrecht, R.M.2
  • 27
    • 33644762820 scopus 로고    scopus 로고
    • The in vitro absorption of microfine zinc oxide and titanium dioxide through porcine skin
    • A. O. Gamer E. Leibold B. van Ravenzwaay The in vitro absorption of microfine zinc oxide and titanium dioxide through porcine skin Toxicol. in Vitro 2006 20 301 307
    • (2006) Toxicol. in Vitro , vol.20 , pp. 301-307
    • Gamer, A.O.1    Leibold, E.2    Van Ravenzwaay, B.3
  • 29
    • 70049084721 scopus 로고    scopus 로고
    • The safety of nanosized particles in titanium dioxide- and zinc oxide-based sunscreens
    • M. D. Newman M. Stotland J. I. Ellis The safety of nanosized particles in titanium dioxide- and zinc oxide-based sunscreens J. Am. Acad. Dermatol. 2009 61 685 692
    • (2009) J. Am. Acad. Dermatol. , vol.61 , pp. 685-692
    • Newman, M.D.1    Stotland, M.2    Ellis, J.I.3
  • 30
    • 0033870253 scopus 로고    scopus 로고
    • Skin penetration and stabilization of formulations containing microfine titanium dioxide as physical UV filter
    • C. Bennat C. C. Müller-Goymann Skin penetration and stabilization of formulations containing microfine titanium dioxide as physical UV filter Int. J. Cosmet. Sci. 2000 22 4 271 283
    • (2000) Int. J. Cosmet. Sci. , vol.22 , Issue.4 , pp. 271-283
    • Bennat, C.1    Müller-Goymann, C.C.2
  • 31
    • 33846883504 scopus 로고    scopus 로고
    • Effects of mechanical flexion on the penetration of fullerene amino acid- derivatized peptide nanoparticles through skin
    • J. G. Rouse J. Yang J. P. Ryman-Rasmussen A. R. Barron N. A. Monteiro-Riviere Effects of mechanical flexion on the penetration of fullerene amino acid- derivatized peptide nanoparticles through skin Nano Lett. 2007 7 1 155 160
    • (2007) Nano Lett. , vol.7 , Issue.1 , pp. 155-160
    • Rouse, J.G.1    Yang, J.2    Ryman-Rasmussen, J.P.3    Barron, A.R.4    Monteiro-Riviere, N.A.5
  • 32
    • 65649110160 scopus 로고    scopus 로고
    • In vivo acute toxicity of titanium dioxide nanoparticles to mice after intraperitioneal injection
    • J. Chen X. Dong J. Zhao G. Tang In vivo acute toxicity of titanium dioxide nanoparticles to mice after intraperitioneal injection J. Appl. Toxicol. 2009 29 330 337
    • (2009) J. Appl. Toxicol. , vol.29 , pp. 330-337
    • Chen, J.1    Dong, X.2    Zhao, J.3    Tang, G.4
  • 33
  • 40
    • 85070990278 scopus 로고    scopus 로고
    • Deposition, Retention and Clearance, and Translocation of Inhaled Fine and Nano-Particles in the Respiratory Tract
    • ed. Gehr, C. Mühlfeld, B. Rothen Rutishauser and F. Blank, Informa Healthcare, USA, New York, 2nd edn, ch. 5
    • W. Möller, W. G. Kreyling, O. Schmid, M. Semmler-Behnke and H. Schulz, Deposition, Retention and Clearance, and Translocation of Inhaled Fine and Nano-Particles in the Respiratory Tract, in Particle-Lung Interactions, ed., P. Gehr, C. Mühlfeld, B. Rothen Rutishauser, and, F. Blank, Informa Healthcare, USA, New York, 2nd edn, 2009, ch. 5, pp. 79-107
    • (2009) Particle-Lung Interactions , pp. 79-107
    • Möller, W.1    Kreyling, W.G.2    Schmid, O.3    Semmler-Behnke, M.4    Schulz, H.5
  • 41
    • 34249901318 scopus 로고    scopus 로고
    • Dendritic cells and macrophages form a transepithelial network against foreign particulate antigens
    • F. Blank B. Rothen-Rutishauser P. Gehr Dendritic cells and macrophages form a transepithelial network against foreign particulate antigens Am. J. Respir. Cell Mol. Biol. 2007 36 669 677
    • (2007) Am. J. Respir. Cell Mol. Biol. , vol.36 , pp. 669-677
    • Blank, F.1    Rothen-Rutishauser, B.2    Gehr, P.3
  • 44
    • 0014002045 scopus 로고
    • High concentration of injected titanium dioxide in abdominal lymph nodes
    • C. B. Huggins J. P. Froehlich High concentration of injected titanium dioxide in abdominal lymph nodes J. Exp. Med. 1966 124 1099 1106
    • (1966) J. Exp. Med. , vol.124 , pp. 1099-1106
    • Huggins, C.B.1    Froehlich, J.P.2
  • 50
    • 79955634536 scopus 로고    scopus 로고
    • Lung exposure of titanium dioxide nanoparticles induces innate immune activation and long-lasting lymphocyte response in the Dark Agouti rat
    • Å. Gustafsson E. Lindstedt L. S. Elfsmark A. Bucht Lung exposure of titanium dioxide nanoparticles induces innate immune activation and long-lasting lymphocyte response in the Dark Agouti rat J. Immunotoxicol. 2011 8 2 111 121
    • (2011) J. Immunotoxicol. , vol.8 , Issue.2 , pp. 111-121
    • Gustafsson, Å.1    Lindstedt, E.2    Elfsmark, L.S.3    Bucht, A.4
  • 58
    • 84885728931 scopus 로고    scopus 로고
    • Histologic and apoptotic changes induced by titanium dioxide nanoparticles in the livers of rats
    • S. Alarifi D. Ali A. A. Al-Doaiss B. A. Ali M. Ahmed A. A. Al-Khedhairy Histologic and apoptotic changes induced by titanium dioxide nanoparticles in the livers of rats Int. J. Nanomed. 2013 8 3937 3943
    • (2013) Int. J. Nanomed. , vol.8 , pp. 3937-3943
    • Alarifi, S.1    Ali, D.2    Al-Doaiss, A.A.3    Ali, B.A.4    Ahmed, M.5    Al-Khedhairy, A.A.6
  • 60
    • 85014848102 scopus 로고    scopus 로고
    • (in Russian)
    • (in Russian)
  • 61
    • 84952640002 scopus 로고    scopus 로고
    • Amelioration of titanium dioxide nanoparticles-induced liver injury in mice: Possible role of some antioxidants
    • S. A. Azim H. A. Darwish M. Z. Rizk S. A. Ali M. O. Kadry Amelioration of titanium dioxide nanoparticles-induced liver injury in mice: possible role of some antioxidants Exp. Toxicol. Pathol. 2015 67 4 305 314
    • (2015) Exp. Toxicol. Pathol. , vol.67 , Issue.4 , pp. 305-314
    • Azim, S.A.1    Darwish, H.A.2    Rizk, M.Z.3    Ali, S.A.4    Kadry, M.O.5
  • 64
    • 84961783404 scopus 로고    scopus 로고
    • Toxic effects of titanium dioxide nanoparticles and titanium dioxide bulk salt in the liver and blood of male Sprague-Dawley rats assessed by different assays
    • M. Shakeel F. Jabeen A. N. Qureshi M. Fakhr-e-Alam Toxic effects of titanium dioxide nanoparticles and titanium dioxide bulk salt in the liver and blood of male Sprague-Dawley rats assessed by different assays Biol. Trace Elem. Res. 2016 173 2 1 22
    • (2016) Biol. Trace Elem. Res. , vol.173 , Issue.2 , pp. 1-22
    • Shakeel, M.1    Jabeen, F.2    Qureshi, A.N.3    Fakhr-E-Alam, M.4
  • 65
    • 84934992806 scopus 로고    scopus 로고
    • 2 nanoparticle-induced genotoxicity persistence and possible chronic gastritis-induction in mice
    • 2 nanoparticle-induced genotoxicity persistence and possible chronic gastritis-induction in mice Food Chem. Toxicol. 2015 83 76 83
    • (2015) Food Chem. Toxicol. , vol.83 , pp. 76-83
    • Ramadan, H.1    Mohamed, H.2
  • 66
    • 77953356980 scopus 로고    scopus 로고
    • Acute toxicity study of the interaction between titanium dioxide nanoparticles and lead acetate in mice
    • R. Zhang Y. Niu Y. Li C. Zhao B. Song Y. Lia Y. Zhou Acute toxicity study of the interaction between titanium dioxide nanoparticles and lead acetate in mice Environ. Toxicol. Pharmacol. 2010 30 1 52 60
    • (2010) Environ. Toxicol. Pharmacol. , vol.30 , Issue.1 , pp. 52-60
    • Zhang, R.1    Niu, Y.2    Li, Y.3    Zhao, C.4    Song, B.5    Lia, Y.6    Zhou, Y.7
  • 70
    • 84924904522 scopus 로고    scopus 로고
    • Titanium nanoparticle inhalation induces renal fibrosis in mice via an OS upregulated transforming growth factor-β pathway
    • K. T. Huang C. T. Wu K. H. Huang W. C. Lin C. M. Chen S. S. Guan C. K. Chiang S. H. Liu Titanium nanoparticle inhalation induces renal fibrosis in mice via an OS upregulated transforming growth factor-β pathway Chem. Res. Toxicol. 2015 28 3 354 364
    • (2015) Chem. Res. Toxicol. , vol.28 , Issue.3 , pp. 354-364
    • Huang, K.T.1    Wu, C.T.2    Huang, K.H.3    Lin, W.C.4    Chen, C.M.5    Guan, S.S.6    Chiang, C.K.7    Liu, S.H.8
  • 79
    • 84899136300 scopus 로고    scopus 로고
    • Systemic immune effects of titanium dioxide nanoparticles after repeated intratracheal instillation in rat
    • Y. Fu Y. Zhang X. Chang Y. Zhang S. Ma J. Sui L. Yin Y. Pu G. Liang Systemic immune effects of titanium dioxide nanoparticles after repeated intratracheal instillation in rat Int. J. Mol. Sci. 2014 15 4 6961 6973
    • (2014) Int. J. Mol. Sci. , vol.15 , Issue.4 , pp. 6961-6973
    • Fu, Y.1    Zhang, Y.2    Chang, X.3    Zhang, Y.4    Ma, S.5    Sui, J.6    Yin, L.7    Pu, Y.8    Liang, G.9
  • 80
    • 79751516728 scopus 로고    scopus 로고
    • An increase in mouse tumor growth by an in vivo immunomodulating effect of titanium dioxide nanoparticles
    • E. Y. Moon G. H. Yi J. S. Kang J. S. Lim H. M. Kim S. Pyo An increase in mouse tumor growth by an in vivo immunomodulating effect of titanium dioxide nanoparticles J. Immunotoxicol. 2011 8 1 56 67
    • (2011) J. Immunotoxicol. , vol.8 , Issue.1 , pp. 56-67
    • Moon, E.Y.1    Yi, G.H.2    Kang, J.S.3    Lim, J.S.4    Kim, H.M.5    Pyo, S.6
  • 84
    • 71549145597 scopus 로고    scopus 로고
    • Nanosized titanium dioxide enhanced inflammatory responses in the septic brain of mouse
    • J. A. Shin E. J. Lee S. M. Seo H. S. Kim J. L. Kang E. M. Park Nanosized titanium dioxide enhanced inflammatory responses in the septic brain of mouse Neurosci. 2010 165 445 454
    • (2010) Neurosci. , vol.165 , pp. 445-454
    • Shin, J.A.1    Lee, E.J.2    Seo, S.M.3    Kim, H.S.4    Kang, J.L.5    Park, E.M.6
  • 94
  • 96
    • 84887609813 scopus 로고    scopus 로고
    • Prenatal exposure to nanoparticulate titanium dioxide enhances depressive-like behaviors in adult rats
    • Y. Cui X. Chen Z. Zhou Y. Lei M. Ma R. Cao T. Sun J. Xu M. Huo C. Wen Y. Che Prenatal exposure to nanoparticulate titanium dioxide enhances depressive-like behaviors in adult rats Chemosphere 2014 96 99 104
    • (2014) Chemosphere , vol.96 , pp. 99-104
    • Cui, Y.1    Chen, X.2    Zhou, Z.3    Lei, Y.4    Ma, M.5    Cao, R.6    Sun, T.7    Xu, J.8    Huo, M.9    Wen, C.10    Che, Y.11
  • 99
    • 84961990869 scopus 로고    scopus 로고
    • Cardiac inflammation involving in PKCϵ or ERK1/2 -activated NF-κB signalling pathway in mice following exposure to titanium dioxide nanoparticles
    • X. H. Yu F. S. Hong Y. Q. Zhang Cardiac inflammation involving in PKCϵ or ERK1/2 -activated NF-κB signalling pathway in mice following exposure to titanium dioxide nanoparticles J. Hazard. Mater. 2016 313 68 77
    • (2016) J. Hazard. Mater. , vol.313 , pp. 68-77
    • Yu, X.H.1    Hong, F.S.2    Zhang, Y.Q.3
  • 101
    • 84962964628 scopus 로고    scopus 로고
    • Intratracheally instilled titanium dioxide nano-particles translocate to heart and liver and activate complement cascade in the heart of C57BL/6 mice
    • M. Husain D. Wu A. T. Saber N. Decan N. R. Jacobsen A. Williams C. L. Yauk H. Wallin U. Vogel S. Halappanavar Intratracheally instilled titanium dioxide nano-particles translocate to heart and liver and activate complement cascade in the heart of C57BL/6 mice Nanotoxicology 2015 20 1 10
    • (2015) Nanotoxicology , vol.20 , pp. 1-10
    • Husain, M.1    Wu, D.2    Saber, A.T.3    Decan, N.4    Jacobsen, N.R.5    Williams, A.6    Yauk, C.L.7    Wallin, H.8    Vogel, U.9    Halappanavar, S.10
  • 104
    • 84867502940 scopus 로고    scopus 로고
    • Nanoparticle inhalation alters systemic arteriolar vasoreactivity through sympathetic and cyclooxygenase-mediated pathways
    • T. L. Knuckles J. Yi D. G. Frazer H. D. Leonard B. T. Chen V. Castranova T. R. Nurkiewicz Nanoparticle inhalation alters systemic arteriolar vasoreactivity through sympathetic and cyclooxygenase-mediated pathways Nanotoxicology 2012 6 7 724 735
    • (2012) Nanotoxicology , vol.6 , Issue.7 , pp. 724-735
    • Knuckles, T.L.1    Yi, J.2    Frazer, D.G.3    Leonard, H.D.4    Chen, B.T.5    Castranova, V.6    Nurkiewicz, T.R.7
  • 105
    • 77951126792 scopus 로고    scopus 로고
    • Nanoparticle inhalation impairs coronary microvascular reactivity via a local reactive oxygen species-dependent mechanism
    • A. J. LeBlanc A. M. Moseley B. T. Chen D. Frazer V. Castranova T. R. Nurkiewicz Nanoparticle inhalation impairs coronary microvascular reactivity via a local reactive oxygen species-dependent mechanism Cardiovasc. Toxicol. 2010 10 1 27 36
    • (2010) Cardiovasc. Toxicol. , vol.10 , Issue.1 , pp. 27-36
    • LeBlanc, A.J.1    Moseley, A.M.2    Chen, B.T.3    Frazer, D.4    Castranova, V.5    Nurkiewicz, T.R.6
  • 111
    • 84876903851 scopus 로고    scopus 로고
    • Cardiovascular effects of pulmonary exposure to titanium dioxide nanoparticles in ApoE knockout mice
    • T. Chen J. Hu C. Chen J. Pu X. Cui G. Jia Cardiovascular effects of pulmonary exposure to titanium dioxide nanoparticles in ApoE knockout mice J. Nanosci. Nanotechnol. 2013 13 5 3214 3222
    • (2013) J. Nanosci. Nanotechnol. , vol.13 , Issue.5 , pp. 3214-3222
    • Chen, T.1    Hu, J.2    Chen, C.3    Pu, J.4    Cui, X.5    Jia, G.6
  • 114
    • 84896711604 scopus 로고    scopus 로고
    • 2 exposure on testosterone synthesis and spermatogenesis in mice
    • 2 exposure on testosterone synthesis and spermatogenesis in mice Arch. Toxicol. 2014 8 3 781 788
    • (2014) Arch. Toxicol. , vol.8 , Issue.3 , pp. 781-788
    • Jia, F.1    Sun, Z.2    Yan, X.3    Zhou, B.4    Wang, J.5
  • 119
    • 84921022915 scopus 로고    scopus 로고
    • Cytotoxic and genotoxic effects of titanium dioxide nanoparticles in testicular cells of male wistar rat
    • R. Meena K. Kajal Cytotoxic and genotoxic effects of titanium dioxide nanoparticles in testicular cells of male wistar rat Appl. Biochem. Biotechnol. 2015 175 2 825 840
    • (2015) Appl. Biochem. Biotechnol. , vol.175 , Issue.2 , pp. 825-840
    • Meena, R.1    Kajal, K.2
  • 121
    • 67349194080 scopus 로고    scopus 로고
    • Pulmonary toxicity induced by three forms of titanium dioxide nanoparticles via intra-tracheal instillation in rats
    • R. Liu L. Yin Y. Pu G. Liang J. Zhang Y. Su Z. Xiao B. Ye Pulmonary toxicity induced by three forms of titanium dioxide nanoparticles via intra-tracheal instillation in rats Prog. Nat. Sci. 2009 19 573 579
    • (2009) Prog. Nat. Sci. , vol.19 , pp. 573-579
    • Liu, R.1    Yin, L.2    Pu, Y.3    Liang, G.4    Zhang, J.5    Su, Y.6    Xiao, Z.7    Ye, B.8
  • 123
    • 84896471949 scopus 로고    scopus 로고
    • Route-dependent systemic and local immune effects following exposure to solutions prepared from titanium dioxide nanoparticles
    • W. Auttachoat C. E. McLoughlin K. L. White Jr. M. J. Smith Route-dependent systemic and local immune effects following exposure to solutions prepared from titanium dioxide nanoparticles J. Immunotoxicol. 2014 11 3 273 282
    • (2014) J. Immunotoxicol. , vol.11 , Issue.3 , pp. 273-282
    • Auttachoat, W.1    McLoughlin, C.E.2    White, K.L.3    Smith, M.J.4
  • 124
    • 84892747331 scopus 로고    scopus 로고
    • Equivalent titanium dioxide nanoparticle deposition by intratracheal instillation and whole body inhalation: The effect of dose rate on acute respiratory tract inflammation
    • B. L. Baisch N. M. Corson P. Wade-Mercer R. Gelein A. J. Kennell G. Oberdörster A. Elder Equivalent titanium dioxide nanoparticle deposition by intratracheal instillation and whole body inhalation: the effect of dose rate on acute respiratory tract inflammation Part. Fibre Toxicol. 2014 11 5
    • (2014) Part. Fibre Toxicol. , vol.11 , pp. 5
    • Baisch, B.L.1    Corson, N.M.2    Wade-Mercer, P.3    Gelein, R.4    Kennell, A.J.5    Oberdörster, G.6    Elder, A.7
  • 125
    • 79959904775 scopus 로고    scopus 로고
    • Pulmonary response to surface-coated nanotitanium dioxide particles includes induction of acute phase response genes, inflammatory cascades, and changes in microRNAs: A toxicogenomic study
    • S. Halappanavar P. Jackson A. Williams K. A. Jensen K. S. Hougaard U. Vogel C. L. Yauk H. Wallin Pulmonary response to surface-coated nanotitanium dioxide particles includes induction of acute phase response genes, inflammatory cascades, and changes in microRNAs: a toxicogenomic study Environ. Mol. Mutagen. 2011 52 425 439
    • (2011) Environ. Mol. Mutagen. , vol.52 , pp. 425-439
    • Halappanavar, S.1    Jackson, P.2    Williams, A.3    Jensen, K.A.4    Hougaard, K.S.5    Vogel, U.6    Yauk, C.L.7    Wallin, H.8
  • 126
    • 67449103004 scopus 로고    scopus 로고
    • Influence of different sizes of titanium dioxide nanoparticles on hepatic and renal functions in rats with correlation to oxidative stress
    • G. Liang Y. Pu L. Yin R. Liu B. Ye Y. Su Y. Li Influence of different sizes of titanium dioxide nanoparticles on hepatic and renal functions in rats with correlation to oxidative stress J. Toxicol. Environ. Health, Part A. 2009 72 11-12 740 745
    • (2009) J. Toxicol. Environ. Health, Part A. , vol.72 , Issue.1112 , pp. 740-745
    • Liang, G.1    Pu, Y.2    Yin, L.3    Liu, R.4    Ye, B.5    Su, Y.6    Li, Y.7
  • 130
    • 84962036343 scopus 로고    scopus 로고
    • Amelioration of titanium dioxide nanoparticles-induced liver injury in mice: Possible role of some antioxidants
    • S. A. A. Azim H. A. Darwish M. Z. Rizk S. A. Ali M. O. Kadry Amelioration of titanium dioxide nanoparticles-induced liver injury in mice: Possible role of some antioxidants Exp. Toxicol. Pathol. 2015 3 5 14
    • (2015) Exp. Toxicol. Pathol. , vol.3 , pp. 5-14
    • Azim, S.A.A.1    Darwish, H.A.2    Rizk, M.Z.3    Ali, S.A.4    Kadry, M.O.5
  • 131
    • 75749115134 scopus 로고    scopus 로고
    • Titanium dioxide induces different levels of IL-1beta production dependent on its particle characteristics through caspase-1 activation mediated by reactive oxygen species and cathepsin B
    • T. Morishige Y. Yoshioka A. Tanabe X. Yao S. Tsunoda Y. Tsutsumi Y. Mukai N. Okada S. Nakagawa Titanium dioxide induces different levels of IL-1beta production dependent on its particle characteristics through caspase-1 activation mediated by reactive oxygen species and cathepsin B Biochem. Biophys. Res. Commun. 2010 392 2 160 165
    • (2010) Biochem. Biophys. Res. Commun. , vol.392 , Issue.2 , pp. 160-165
    • Morishige, T.1    Yoshioka, Y.2    Tanabe, A.3    Yao, X.4    Tsunoda, S.5    Tsutsumi, Y.6    Mukai, Y.7    Okada, N.8    Nakagawa, S.9
  • 132
    • 84887292565 scopus 로고    scopus 로고
    • Potential impact of quercetin and idebenone against immuno-inflammatory and oxidative renal damage induced in rats by titanium dioxide nanoparticles toxicity
    • N. M. Al-Rasheed L. M. Faddah A. M. Mohamed N. A. Abdel Baky N. M. Al-Rasheed R. A. Mohammad Potential impact of quercetin and idebenone against immuno-inflammatory and oxidative renal damage induced in rats by titanium dioxide nanoparticles toxicity J. Oleo Sci. 2013 62 11 961 971
    • (2013) J. Oleo Sci. , vol.62 , Issue.11 , pp. 961-971
    • Al-Rasheed, N.M.1    Faddah, L.M.2    Mohamed, A.M.3    Abdel Baky, N.A.4    Al-Rasheed, N.M.5    Mohammad, R.A.6
  • 135
    • 71849101617 scopus 로고    scopus 로고
    • Ooxidative stress and apoptosis induced by nanosized titanium dioxide in PC12 cells
    • S. Liu L. Xu T. Zhang G. Ren Z. Yang Ooxidative stress and apoptosis induced by nanosized titanium dioxide in PC12 cells Toxicology 2010 267 1-3 172 177
    • (2010) Toxicology , vol.267 , Issue.13 , pp. 172-177
    • Liu, S.1    Xu, L.2    Zhang, T.3    Ren, G.4    Yang, Z.5
  • 140
    • 84939271702 scopus 로고    scopus 로고
    • Titanium dioxide nanoparticles increase plasma glucose via reactive oxygen species-induced insulin resistance in mice
    • H. Hu Q. Guo C. Wang X. Ma H. He Y. Oh Y. Feng Q. Wu N. Gu Titanium dioxide nanoparticles increase plasma glucose via reactive oxygen species-induced insulin resistance in mice J. Appl. Toxicol. 2015 55 10 1122 1132
    • (2015) J. Appl. Toxicol. , vol.55 , Issue.10 , pp. 1122-1132
    • Hu, H.1    Guo, Q.2    Wang, C.3    Ma, X.4    He, H.5    Oh, Y.6    Feng, Y.7    Wu, Q.8    Gu, N.9
  • 141
    • 67650457630 scopus 로고    scopus 로고
    • Titanium dioxide nanoparticles induce apoptosis through the JNK/p38-caspase-8-Bid pathway in phytohemagglutinin-stimulated human lymphocytes
    • S. J. Kang B. M. Kim Y. J. Lee S. H. Hong H. W. Chung Titanium dioxide nanoparticles induce apoptosis through the JNK/p38-caspase-8-Bid pathway in phytohemagglutinin-stimulated human lymphocytes Biochem. Biophys. Res. Commun. 2009 386 4 682 687
    • (2009) Biochem. Biophys. Res. Commun. , vol.386 , Issue.4 , pp. 682-687
    • Kang, S.J.1    Kim, B.M.2    Lee, Y.J.3    Hong, S.H.4    Chung, H.W.5
  • 144
    • 1942484815 scopus 로고    scopus 로고
    • Inhaled particles and lung cancer, part B: Paradigms and risk assessment
    • P. J. Borm R. P. Schins C. Albrecht Inhaled particles and lung cancer, part B: paradigms and risk assessment Int. J. Cancer 2004 110 3 14
    • (2004) Int. J. Cancer , vol.110 , pp. 3-14
    • Borm, P.J.1    Schins, R.P.2    Albrecht, C.3
  • 145
    • 33645793105 scopus 로고    scopus 로고
    • Carcinogenicity study with nineteen granular dusts in rats
    • F. Pott M. Roller Carcinogenicity study with nineteen granular dusts in rats Eur. J. Oncol. 2005 10 249
    • (2005) Eur. J. Oncol. , vol.10 , pp. 249
    • Pott, F.1    Roller, M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.