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Volumn 165, Issue 2, 2010, Pages 445-454

Nanosized titanium dioxide enhanced inflammatory responses in the septic brain of mouse

Author keywords

LPS; microglia; nanoparticle; neuroinflammation; sepsis; ultrafine TiO2

Indexed keywords

CYTOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; MESSENGER RNA; REACTIVE OXYGEN METABOLITE; RNA; TITANIUM DIOXIDE; TUMOR NECROSIS FACTOR ALPHA;

EID: 71549145597     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2009.10.057     Document Type: Article
Times cited : (87)

References (57)
  • 1
    • 0031709894 scopus 로고    scopus 로고
    • Cytotoxicity, pro-oxidant effects and antioxidant depletion in rat lung alveolar macrophages exposed to ultrafine titanium dioxide
    • Afaq F., Abidi P., Matin R., and Rahman Q. Cytotoxicity, pro-oxidant effects and antioxidant depletion in rat lung alveolar macrophages exposed to ultrafine titanium dioxide. J Appl Toxicol 18 (1998) 307-312
    • (1998) J Appl Toxicol , vol.18 , pp. 307-312
    • Afaq, F.1    Abidi, P.2    Matin, R.3    Rahman, Q.4
  • 2
    • 0025162755 scopus 로고
    • Brain microglia constitutively express beta-2 integrins
    • Akiyama H., and McGeer P.L. Brain microglia constitutively express beta-2 integrins. J Neuroimmunol 30 (1990) 81-93
    • (1990) J Neuroimmunol , vol.30 , pp. 81-93
    • Akiyama, H.1    McGeer, P.L.2
  • 4
    • 1342267646 scopus 로고    scopus 로고
    • Pulmonary responses of mice, rats, and hamsters to subchronic inhalation of ultrafine titanium dioxide particles
    • Bermudez E., Mangum J.B., Wong B.A., Asgharian B., Hext P.M., Warheit D.B., and Everitt J.I. Pulmonary responses of mice, rats, and hamsters to subchronic inhalation of ultrafine titanium dioxide particles. Toxicol Sci 77 (2004) 347-357
    • (2004) Toxicol Sci , vol.77 , pp. 347-357
    • Bermudez, E.1    Mangum, J.B.2    Wong, B.A.3    Asgharian, B.4    Hext, P.M.5    Warheit, D.B.6    Everitt, J.I.7
  • 5
    • 0032032424 scopus 로고    scopus 로고
    • Extracellular signal-regulated kinase and p38 subgroups of mitogen-activated protein kinases regulate inducible nitric oxide synthase and tumor necrosis factor-alpha gene expression in endotoxin-stimulated primary glial cultures
    • Bhat N.R., Zhang P., Lee J.C., and Hogan E.L. Extracellular signal-regulated kinase and p38 subgroups of mitogen-activated protein kinases regulate inducible nitric oxide synthase and tumor necrosis factor-alpha gene expression in endotoxin-stimulated primary glial cultures. J Neurosci 18 (1998) 1633-1641
    • (1998) J Neurosci , vol.18 , pp. 1633-1641
    • Bhat, N.R.1    Zhang, P.2    Lee, J.C.3    Hogan, E.L.4
  • 6
    • 0030008052 scopus 로고    scopus 로고
    • Superoxide production in rat hippocampal neurons: selective imaging with hydroethidine
    • Bindokas V.P., Jordan J., Lee C.C., and Miller R.J. Superoxide production in rat hippocampal neurons: selective imaging with hydroethidine. J Neurosci 16 (1996) 1324-1336
    • (1996) J Neurosci , vol.16 , pp. 1324-1336
    • Bindokas, V.P.1    Jordan, J.2    Lee, C.C.3    Miller, R.J.4
  • 8
    • 0035214647 scopus 로고    scopus 로고
    • Systemic LPS injection leads to granulocyte influx into normal and injured brain: effects of ICAM-1 deficiency
    • Bohatschek M., Werner A., and Raivich G. Systemic LPS injection leads to granulocyte influx into normal and injured brain: effects of ICAM-1 deficiency. Exp Neurol 172 (2001) 137-152
    • (2001) Exp Neurol 172 , pp. 137-152
    • Bohatschek, M.1    Werner, A.2    Raivich, G.3
  • 11
    • 0028369668 scopus 로고
    • Intracellular hydrogen peroxide and superoxide anion detection in endothelial cells
    • Carter W.O., Narayanan P.K., and Robinson J.P. Intracellular hydrogen peroxide and superoxide anion detection in endothelial cells. J Leukoc Biol 55 (1994) 253-258
    • (1994) J Leukoc Biol , vol.55 , pp. 253-258
    • Carter, W.O.1    Narayanan, P.K.2    Robinson, J.P.3
  • 12
    • 65649110160 scopus 로고    scopus 로고
    • In vivo acute toxicity of titanium dioxide nanoparticles to mice after intraperitioneal injection
    • Chen J., Dong X., Zhao J., and Tang G. In vivo acute toxicity of titanium dioxide nanoparticles to mice after intraperitioneal injection. J Appl Toxicol 29 (2009) 330-337
    • (2009) J Appl Toxicol , vol.29 , pp. 330-337
    • Chen, J.1    Dong, X.2    Zhao, J.3    Tang, G.4
  • 13
  • 14
    • 0037389801 scopus 로고    scopus 로고
    • Protective effect of glial cells against lipopolysaccharide-mediated blood-brain barrier injury
    • Descamps L., Coisne C., Dehouck B., Cecchelli R., and Torpier G. Protective effect of glial cells against lipopolysaccharide-mediated blood-brain barrier injury. Glia 42 (2003) 46-58
    • (2003) Glia , vol.42 , pp. 46-58
    • Descamps, L.1    Coisne, C.2    Dehouck, B.3    Cecchelli, R.4    Torpier, G.5
  • 15
    • 0037235805 scopus 로고    scopus 로고
    • The role of free radicals in the toxic and inflammatory effects of four different ultrafine particle types
    • Dick C.A., Brown D.M., Donaldson K., and Stone V. The role of free radicals in the toxic and inflammatory effects of four different ultrafine particle types. Inhal Toxicol 15 (2003) 39-52
    • (2003) Inhal Toxicol , vol.15 , pp. 39-52
    • Dick, C.A.1    Brown, D.M.2    Donaldson, K.3    Stone, V.4
  • 16
    • 41849120840 scopus 로고    scopus 로고
    • Tissue distribution and toxicity of intravenously administered titanium dioxide nanoparticles in rats
    • Fabian E., Landsiedel R., Ma-Hock L., Wiench K., Wohlleben W., and van Ravenzwaay B. Tissue distribution and toxicity of intravenously administered titanium dioxide nanoparticles in rats. Arch Toxicol 82 (2008) 151-157
    • (2008) Arch Toxicol , vol.82 , pp. 151-157
    • Fabian, E.1    Landsiedel, R.2    Ma-Hock, L.3    Wiench, K.4    Wohlleben, W.5    van Ravenzwaay, B.6
  • 17
    • 0032942060 scopus 로고    scopus 로고
    • Microglia as mediators of inflammatory and degenerative diseases
    • Gonzalez-Scarano F., and Baltuch G. Microglia as mediators of inflammatory and degenerative diseases. Annu Rev Neurosci 22 (1999) 219-240
    • (1999) Annu Rev Neurosci , vol.22 , pp. 219-240
    • Gonzalez-Scarano, F.1    Baltuch, G.2
  • 18
    • 23944463473 scopus 로고    scopus 로고
    • Ultrafine titanium dioxide particles in the absence of photoactivation can induce oxidative damage to human bronchial epithelial cells
    • Gurr J.R., Wang A.S., Chen C.H., and Jan K.Y. Ultrafine titanium dioxide particles in the absence of photoactivation can induce oxidative damage to human bronchial epithelial cells. Toxicology 213 (2005) 66-73
    • (2005) Toxicology , vol.213 , pp. 66-73
    • Gurr, J.R.1    Wang, A.S.2    Chen, C.H.3    Jan, K.Y.4
  • 19
    • 33845346100 scopus 로고    scopus 로고
    • Nanoparticles: health effects-pros and cons
    • Gwinn M.R., and Vallyathan V. Nanoparticles: health effects-pros and cons. Environ Health Perspect 114 (2006) 1818-1825
    • (2006) Environ Health Perspect , vol.114 , pp. 1818-1825
    • Gwinn, M.R.1    Vallyathan, V.2
  • 20
    • 23944525131 scopus 로고    scopus 로고
    • Titanium dioxide: inhalation toxicology and epidemiology
    • Hext P.M., Tomenson J.A., and Thompson P. Titanium dioxide: inhalation toxicology and epidemiology. Ann Occup Hyg 49 (2005) 461-472
    • (2005) Ann Occup Hyg , vol.49 , pp. 461-472
    • Hext, P.M.1    Tomenson, J.A.2    Thompson, P.3
  • 21
    • 40749098186 scopus 로고    scopus 로고
    • Comparison of the biological activity between ultrafine and fine titanium dioxide particles in RAW 264.7 cells associated with oxidative stress
    • Kang J.L., Moon C., Lee H.S., Lee H.W., Park E.M., Kim H.S., and Castranova V. Comparison of the biological activity between ultrafine and fine titanium dioxide particles in RAW 264.7 cells associated with oxidative stress. J Toxicol Environ Health A 71 (2008) 478-485
    • (2008) J Toxicol Environ Health A , vol.71 , pp. 478-485
    • Kang, J.L.1    Moon, C.2    Lee, H.S.3    Lee, H.W.4    Park, E.M.5    Kim, H.S.6    Castranova, V.7
  • 22
    • 42649113710 scopus 로고    scopus 로고
    • Inhaled ultrafine particulate matter affects CNS inflammatory processes and may act via MAP kinase signaling pathways
    • Kleinman M.T., Araujo J.A., Nel A., Sioutas C., Campbell A., Cong P.Q., Li H., and Bondy S.C. Inhaled ultrafine particulate matter affects CNS inflammatory processes and may act via MAP kinase signaling pathways. Toxicol Lett 178 (2008) 127-130
    • (2008) Toxicol Lett , vol.178 , pp. 127-130
    • Kleinman, M.T.1    Araujo, J.A.2    Nel, A.3    Sioutas, C.4    Campbell, A.5    Cong, P.Q.6    Li, H.7    Bondy, S.C.8
  • 23
    • 16944366242 scopus 로고    scopus 로고
    • Reduction of CuZn-superoxide dismutase activity exacerbates neuronal cell injury and edema formation after transient focal cerebral ischemia
    • Kondo T., Reaume A.G., Huang T.T., Carlson E., Murakami K., Chen S.F., Hoffman E.K., Scott R.W., Epstein C.J., and Chan P.H. Reduction of CuZn-superoxide dismutase activity exacerbates neuronal cell injury and edema formation after transient focal cerebral ischemia. J Neurosci 17 (1997) 4180-4189
    • (1997) J Neurosci , vol.17 , pp. 4180-4189
    • Kondo, T.1    Reaume, A.G.2    Huang, T.T.3    Carlson, E.4    Murakami, K.5    Chen, S.F.6    Hoffman, E.K.7    Scott, R.W.8    Epstein, C.J.9    Chan, P.H.10
  • 25
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method
    • Livak K.J., and Schmittgen T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 25 (2001) 402-408
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 26
    • 33746255334 scopus 로고    scopus 로고
    • Titanium dioxide (P25) produces reactive oxygen species in immortalized brain microglia (BV2): implications for nanoparticle neurotoxicity
    • Long T.C., Saleh N., Tilton R.D., Lowry G.V., and Veronesi B. Titanium dioxide (P25) produces reactive oxygen species in immortalized brain microglia (BV2): implications for nanoparticle neurotoxicity. Environ Sci Technol 40 (2006) 4346-4352
    • (2006) Environ Sci Technol , vol.40 , pp. 4346-4352
    • Long, T.C.1    Saleh, N.2    Tilton, R.D.3    Lowry, G.V.4    Veronesi, B.5
  • 28
    • 53649091140 scopus 로고    scopus 로고
    • Pt/TiO2 brain biocompatible nanoparticles: GBM treatment using the C6 model in Wistar rats
    • Lopez T., Recillas S., Guevara P., Sotelo J., Alvarez M., and Odriozola J.A. Pt/TiO2 brain biocompatible nanoparticles: GBM treatment using the C6 model in Wistar rats. Acta Biomater 4 (2008) 2037-2044
    • (2008) Acta Biomater , vol.4 , pp. 2037-2044
    • Lopez, T.1    Recillas, S.2    Guevara, P.3    Sotelo, J.4    Alvarez, M.5    Odriozola, J.A.6
  • 29
  • 31
    • 31944451232 scopus 로고    scopus 로고
    • Toxic potential of materials at the nanolevel
    • Nel A., Xia T., Madler L., and Li N. Toxic potential of materials at the nanolevel. Science 311 (2006) 622-627
    • (2006) Science , vol.311 , pp. 622-627
    • Nel, A.1    Xia, T.2    Madler, L.3    Li, N.4
  • 34
    • 20644449754 scopus 로고    scopus 로고
    • Nanotoxicology: an emerging discipline evolving from studies of ultrafine particles
    • Oberdorster G., Oberdorster E., and Oberdorster J. Nanotoxicology: an emerging discipline evolving from studies of ultrafine particles. Environ Health Perspect 113 (2005) 823-839
    • (2005) Environ Health Perspect , vol.113 , pp. 823-839
    • Oberdorster, G.1    Oberdorster, E.2    Oberdorster, J.3
  • 35
    • 0033596121 scopus 로고    scopus 로고
    • Activators and target genes of Rel/NF-kappaB transcription factors
    • Pahl H.L. Activators and target genes of Rel/NF-kappaB transcription factors. Oncogene 18 (1999) 6853-6866
    • (1999) Oncogene , vol.18 , pp. 6853-6866
    • Pahl, H.L.1
  • 38
    • 33847091290 scopus 로고    scopus 로고
    • Anti-inflammatory mechanisms of isoflavone metabolites in lipopolysaccharide-stimulated microglial cells
    • Park J.S., Woo M.S., Kim D.H., Hyun J.W., Kim W.K., Lee J.C., and Kim H.S. Anti-inflammatory mechanisms of isoflavone metabolites in lipopolysaccharide-stimulated microglial cells. J Pharmacol Exp Ther 320 (2007) 1237-1245
    • (2007) J Pharmacol Exp Ther , vol.320 , pp. 1237-1245
    • Park, J.S.1    Woo, M.S.2    Kim, D.H.3    Hyun, J.W.4    Kim, W.K.5    Lee, J.C.6    Kim, H.S.7
  • 40
    • 33645219531 scopus 로고    scopus 로고
    • Nanomaterial health effects-part 1: background and current knowledge
    • Powell M.C., and Kanarek M.S. Nanomaterial health effects-part 1: background and current knowledge. WMJ 105 (2006) 16-20
    • (2006) WMJ , vol.105 , pp. 16-20
    • Powell, M.C.1    Kanarek, M.S.2
  • 41
    • 33847759064 scopus 로고    scopus 로고
    • Systemic LPS causes chronic neuroinflammation and progressive neurodegeneration
    • Qin L., Wu X., Block M.L., Liu Y., Breese G.R., Hong J.S., Knapp D.J., and Crews F.T. Systemic LPS causes chronic neuroinflammation and progressive neurodegeneration. Glia 55 (2007) 453-462
    • (2007) Glia , vol.55 , pp. 453-462
    • Qin, L.1    Wu, X.2    Block, M.L.3    Liu, Y.4    Breese, G.R.5    Hong, J.S.6    Knapp, D.J.7    Crews, F.T.8
  • 43
    • 25144435958 scopus 로고    scopus 로고
    • Systemic inflammation induces apoptosis with variable vulnerability of different brain regions
    • Semmler A., Okulla T., Sastre M., Dumitrescu-Ozimek L., and Heneka M.T. Systemic inflammation induces apoptosis with variable vulnerability of different brain regions. J Chem Neuroanat 30 (2005) 144-157
    • (2005) J Chem Neuroanat , vol.30 , pp. 144-157
    • Semmler, A.1    Okulla, T.2    Sastre, M.3    Dumitrescu-Ozimek, L.4    Heneka, M.T.5
  • 44
    • 34447628891 scopus 로고    scopus 로고
    • Nanoparticles aggravate heat stress induced cognitive deficits, blood-brain barrier disruption, edema formation and brain pathology
    • Sharma H.S., and Sharma A. Nanoparticles aggravate heat stress induced cognitive deficits, blood-brain barrier disruption, edema formation and brain pathology. Prog Brain Res 162 (2007) 245-273
    • (2007) Prog Brain Res , vol.162 , pp. 245-273
    • Sharma, H.S.1    Sharma, A.2
  • 45
    • 36749027805 scopus 로고    scopus 로고
    • Air pollution, ultrafine and nanoparticle toxicology: cellular and molecular interactions
    • Stone V., Johnston H., and Clift M.J. Air pollution, ultrafine and nanoparticle toxicology: cellular and molecular interactions. IEEE Trans Nanobioscience 6 (2007) 331-340
    • (2007) IEEE Trans Nanobioscience , vol.6 , pp. 331-340
    • Stone, V.1    Johnston, H.2    Clift, M.J.3
  • 46
    • 48849108942 scopus 로고    scopus 로고
    • Safety evaluation of titanium dioxide nanoparticles by their absorption and elimination profiles
    • Sugibayashi K., Todo H., and Kimura E. Safety evaluation of titanium dioxide nanoparticles by their absorption and elimination profiles. J Toxicol Sci 33 (2008) 293-298
    • (2008) J Toxicol Sci , vol.33 , pp. 293-298
    • Sugibayashi, K.1    Todo, H.2    Kimura, E.3
  • 47
    • 0033646585 scopus 로고    scopus 로고
    • Inhalation of poorly soluble particles. II. Influence of particle surface area on inflammation and clearance
    • Tran C.L., Buchanan D., Cullen R.T., Searl A., Jones A.D., and Donaldson K. Inhalation of poorly soluble particles. II. Influence of particle surface area on inflammation and clearance. Inhal Toxicol 12 (2000) 1113-1126
    • (2000) Inhal Toxicol , vol.12 , pp. 1113-1126
    • Tran, C.L.1    Buchanan, D.2    Cullen, R.T.3    Searl, A.4    Jones, A.D.5    Donaldson, K.6
  • 48
    • 56549115351 scopus 로고    scopus 로고
    • Potential neurological lesion after nasal instillation of TiO(2) nanoparticles in the anatase and rutile crystal phases
    • Wang J., Chen C., Liu Y., Jiao F., Li W., Lao F., Li Y., Li B., Ge C., Zhou G., Gao Y., Zhao Y., and Chai Z. Potential neurological lesion after nasal instillation of TiO(2) nanoparticles in the anatase and rutile crystal phases. Toxicol Lett 183 (2008) 72-80
    • (2008) Toxicol Lett , vol.183 , pp. 72-80
    • Wang, J.1    Chen, C.2    Liu, Y.3    Jiao, F.4    Li, W.5    Lao, F.6    Li, Y.7    Li, B.8    Ge, C.9    Zhou, G.10    Gao, Y.11    Zhao, Y.12    Chai, Z.13
  • 49
    • 56049102066 scopus 로고    scopus 로고
    • Time-dependent translocation and potential impairment on central nervous system by intranasally instilled TiO(2) nanoparticles
    • Wang J., Liu Y., Jiao F., Lao F., Li W., Gu Y., Li Y., Ge C., Zhou G., Li B., Zhao Y., Chai Z., and Chen C. Time-dependent translocation and potential impairment on central nervous system by intranasally instilled TiO(2) nanoparticles. Toxicology 254 (2008) 82-90
    • (2008) Toxicology , vol.254 , pp. 82-90
    • Wang, J.1    Liu, Y.2    Jiao, F.3    Lao, F.4    Li, W.5    Gu, Y.6    Li, Y.7    Ge, C.8    Zhou, G.9    Li, B.10    Zhao, Y.11    Chai, Z.12    Chen, C.13
  • 52
    • 34447321045 scopus 로고    scopus 로고
    • Development of a base set of toxicity tests using ultrafine TiO2 particles as a component of nanoparticle risk management
    • Warheit D.B., Hoke R.A., Finlay C., Donner E.M., Reed K.L., and Sayes C.M. Development of a base set of toxicity tests using ultrafine TiO2 particles as a component of nanoparticle risk management. Toxicol Lett 171 (2007) 99-110
    • (2007) Toxicol Lett , vol.171 , pp. 99-110
    • Warheit, D.B.1    Hoke, R.A.2    Finlay, C.3    Donner, E.M.4    Reed, K.L.5    Sayes, C.M.6
  • 53
    • 0038243778 scopus 로고    scopus 로고
    • Selective modulation of lipopolysaccharide-stimulated cytokine expression and mitogen-activated protein kinase pathways by dibutyryl-cAMP in BV2 microglial cells
    • Woo M.S., Jang P.G., Park J.S., Kim W.K., Joh T.H., and Kim H.S. Selective modulation of lipopolysaccharide-stimulated cytokine expression and mitogen-activated protein kinase pathways by dibutyryl-cAMP in BV2 microglial cells. Brain Res Mol Brain Res 113 (2003) 86-96
    • (2003) Brain Res Mol Brain Res , vol.113 , pp. 86-96
    • Woo, M.S.1    Jang, P.G.2    Park, J.S.3    Kim, W.K.4    Joh, T.H.5    Kim, H.S.6
  • 54
    • 70350593880 scopus 로고    scopus 로고
    • Toxicity and penetration of TiO(2) nanoparticles in hairless mice and porcine skin after subchronic dermal exposure
    • in press, in press
    • Wu J, Liu W, Xue C, Zhou S, Lan F, Bi L, Xu H, Yang X, Zeng FD (in press) Toxicity and penetration of TiO(2) nanoparticles in hairless mice and porcine skin after subchronic dermal exposure. Toxicol Lett, in press.
    • Toxicol Lett
    • Wu, J.1    Liu, W.2    Xue, C.3    Zhou, S.4    Lan, F.5    Bi, L.6    Xu, H.7    Yang, X.8    Zeng, F.D.9
  • 55
    • 0036685522 scopus 로고    scopus 로고
    • Inflammation in neurodegenerative disease-a double-edged sword
    • Wyss-Coray T., and Mucke L. Inflammation in neurodegenerative disease-a double-edged sword. Neuron 35 (2002) 419-432
    • (2002) Neuron , vol.35 , pp. 419-432
    • Wyss-Coray, T.1    Mucke, L.2
  • 56
    • 0035970783 scopus 로고    scopus 로고
    • Effect of LPS on the permeability of the blood-brain barrier to insulin
    • Xaio H., Banks W.A., Niehoff M.L., and Morley J.E. Effect of LPS on the permeability of the blood-brain barrier to insulin. Brain Res 896 (2001) 36-42
    • (2001) Brain Res , vol.896 , pp. 36-42
    • Xaio, H.1    Banks, W.A.2    Niehoff, M.L.3    Morley, J.E.4
  • 57
    • 0031870087 scopus 로고    scopus 로고
    • Differences in the extent of inflammation caused by intratracheal exposure to three ultrafine metals: role of free radicals
    • Zhang Q., Kusaka Y., Sato K., Nakakuki K., Kohyama N., and Donaldson K. Differences in the extent of inflammation caused by intratracheal exposure to three ultrafine metals: role of free radicals. J Toxicol Environ Health A 53 (1998) 423-438
    • (1998) J Toxicol Environ Health A , vol.53 , pp. 423-438
    • Zhang, Q.1    Kusaka, Y.2    Sato, K.3    Nakakuki, K.4    Kohyama, N.5    Donaldson, K.6


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