TiO2 nanoparticle-induced neurotoxicity may be involved in dysfunction of glutamate metabolism and its receptor expression in mice

Environmental Toxicology

Volumn 31, Issue 6, 2016, Pages 655-662

  Ze, Xiao ^a   Su, Mingyu ^b   Zhao, Xiaoyang ^a   Jiang, Hao ^a   Hong, Jie ^a   Yu, Xiaohong ^a   Liu, Dong ^a   Xu, Bingqing ^a   Sheng, Lei ^a   Zhou, Qiuping ^a   Zhou, Junling ^a   Cui, Jingwen ^a   Li, Kai ^a   Wang, Ling ^c   Ze, Yuguan ^a   Hong, Fashui ^a  

^a MEDICAL COLLEGE OF SOOCHOW UNIVERSITY   (China)

^b Suzhou Environmental Monitoring Center   (China)

^c SOOCHOW UNIVERSITY   (China)

Author keywords

Glutamate receptors; Glutamate glutamine cyclic pathway; Hippocampus; Mice; Titanium dioxide nanoparticles

Indexed keywords

AMINO ACIDS; BRAIN; ENVIRONMENTAL MANAGEMENT; MAMMALS; METABOLISM; NANOPARTICLES; OXIDES; PHYSIOLOGY; TITANIUM;

GLUTAMATE RECEPTOR; GLUTAMATE-GLUTAMINE CYCLIC PATHWAY; HIPPOCAMPUS; MICE; TITANIUM DIOXIDE NANOPARTICLES;

TITANIUM DIOXIDE;

GLUTAMATE AMMONIA LIGASE; GLUTAMATE RECEPTOR; GLUTAMIC ACID; GLUTAMINASE; GLUTAMINE; METABOTROPIC RECEPTOR 2; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 1; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2B; TITANIUM DIOXIDE NANOPARTICLE; METABOTROPIC RECEPTOR; METAL NANOPARTICLE; NEUROTOXIN; TITANIUM; TITANIUM DIOXIDE;

AMINO ACID; BRAIN; CHEMICAL COMPOUND; ENZYME ACTIVITY; GENE EXPRESSION; METABOLISM; NANOPARTICLE; NEUROLOGY; PROTEIN; RODENT; TOXICITY;

AMINO ACID METABOLISM; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BODY WEIGHT; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; HIPPOCAMPUS; MOUSE; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR GENE; ANIMAL; BRAIN; DOSE RESPONSE; DRUG EFFECTS; GENETICS; INSTITUTE FOR CANCER RESEARCH MOUSE; METABOLISM;

MUS;

ANIMALS; BRAIN; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GENE EXPRESSION; GLUTAMATE-AMMONIA LIGASE; GLUTAMIC ACID; GLUTAMINASE; GLUTAMINE; METAL NANOPARTICLES; MICE; MICE, INBRED ICR; NEUROTOXINS; RECEPTORS, METABOTROPIC GLUTAMATE; TITANIUM;

EID: 84964721884     PISSN: 15204081     EISSN: 15227278     Source Type: Journal    
DOI: 10.1002/tox.22077     Document Type: Article

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